Innovations in pharmacy最新文献

{"title":"Implementation and Evaluation of a Long term Care at Home (Home LTC) Service in a Rural Community Pharmacy Setting.","authors":"Megan Ditzman, Stevie Veach, Jessie Schaefer, Kaitlin Luett, Bryan Kendall, Matthew Witry","doi":"10.24926/iip.v16i1.6469","DOIUrl":"10.24926/iip.v16i1.6469","url":null,"abstract":"<p><p><i>Background:</i> The majority of older Americans are expected to need some level of institutional long term care. Community pharmacies are positioned to delay this need by supporting medication management. There are potential mechanisms for pharmacists to deliver long term care at home (Home LTC) services and bill insurers for services that may delay the transition to a higher level of care. <i>Objectives:</i> This project aims to evaluate the implementation of a community pharmacy delivered Home LTC service in a rural community. The objectives were to: 1) describe implementation and challenges of pharmacy-provided HOME LTC services, 2) attempt billing for Home LTC services, 3) describe pharmacist clinical interventions including drug therapy problems (DTPs) and 4) measure patient/caregiver satisfaction with the service. <i>Methods:</i> This was a pilot evaluation of a community pharmacist delivered intervention. Patient eligibility requirements include taking 6+ medications, having 3+ chronic conditions, and having 2+ limitations in activities of daily living (ADLs). All participants received a comprehensive medication review. Pharmacy staff prepared medications in monthly adherence packaging and delivery was offered. Home visits were performed by the pharmacist as needed. A post study survey assessed satisfaction and invited suggestions for improvement. Patient characteristics, DTPs, interventions, reimbursement attempts and amounts, and survey responses were documented, and analyzed descriptively. <i>Results:</i> Fourteen patients were enrolled in the study - 3 living in a group home and 7 were already receiving adherence packaging. All 14 patients received at least 1 clinical intervention, and 4 home visits were conducted. Seven patients (50%) completed the satisfaction survey and reported universally high satisfaction with the service elements. <i>Conclusion:</i> Overall, implementing a HOME LTC service was successful, however, the pharmacy failed to be reimbursed for service elements, including adherence packaging. Patients were satisfied with the service. Bridging the reimbursement gap is critical to sustainably provide patients with this desired service.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational Licensing Reform: A Step-by-Step Approach for Pharmacy Licensing Boards.","authors":"Alex Adams","doi":"10.24926/iip.v16i1.6458","DOIUrl":"10.24926/iip.v16i1.6458","url":null,"abstract":"<p><p>Occupational licensing reform is essential but challenging for state agencies. This paper presents a step-by-step framework for pharmacy licensing boards, inspired by the Idaho State Board of Pharmacy's (BOP) efforts, which achieved a 75% cut in regulatory page count while creating a more permissive practice environment. By establishing baselines, prioritizing reform areas, and setting clear reduction goals, the BOP streamlined licensing, modernized professional practice standards, and adopted technology-agnostic facility regulations. The transition to enforcement-centric accountability ensured public safety while fostering innovation and economic growth. Early results include increased pharmacy services, improved access, and significant industry investments. This framework offers a replicable approach for other licensing boards to reduce red tape, support economic growth, and enhance regulatory efficiency without compromising health and safety.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective Evaluation and Analysis of Pharmacoequity with Guideline-directed Medical Therapy in Heart Failure with Reduced Ejection Fraction (REAP-HF).","authors":"Morgan Streett, Anna Jacobs, Jennifer Twilla, Kaulin Duncan, Geeth Nadella, Drew A Wells","doi":"10.24926/iip.v16i1.6626","DOIUrl":"10.24926/iip.v16i1.6626","url":null,"abstract":"<p><p><i>Introduction:</i> Patients with heart failure with reduced ejection fraction (HFrEF) who are optimized on guideline-directed medical therapy (GDMT) have improved outcomes; however, medication access and affordability are potential barriers to achieving pharmacoequity. This study sought to compare rates of HFrEF GDMT prescribing at hospital discharge across prescription insurance status groups. <i>Methods:</i> This was a single-center, retrospective cohort study of adult HFrEF patients. Patients were grouped according to prescription insurance status. The primary outcome was the percentage of HFrEF patients prescribed quadruple GDMT at hospital discharge. Key secondary outcomes included the presence of contraindications to therapy and 30-day all-cause readmission rates. The study was approved by the Institutional Review Board at the University of Tennessee Health Science Center. <i>Results:</i> Among the 200 included patients, 63% were male and 92% were black. Discharge on quadruple GDMT across insurance groups was 18% for Medicare Part D, 24% for Medicaid, 24% for commercial, and 33% for uninsured. There was no difference between insurance groups in rates of prescribed quadruple GDMT at hospital discharge (p=0.302) or 30-day hospital readmission (p=0.665). Additionally, there was a significant increase in the number of uninsured patients on quadruple GDMT after hospitalization compared to pre-hospitalization (13% vs 33%, p=0.002). Eighty percent of all patients had a contraindication to at least one GDMT agent. <i>Conclusion:</i> There was no difference in rates of prescribed quadruple GDMT at hospital discharge based on insurance status. However, this study did elucidate the impact of medication access programs improving pharmacoequity in the uninsured patient population.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing Astropharmacy and Sports Pharmacy.","authors":"Ashley Anderson, Ahmer Raza, Shireen Aziz, Misbah Noreen","doi":"10.24926/iip.v16i1.6548","DOIUrl":"10.24926/iip.v16i1.6548","url":null,"abstract":"","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Pharmacy Student-Led Medication Counseling for New Start Anticoagulants on Patient Outcomes and Healthcare Utilization.","authors":"Hannah P McCullough, Gracie K Daniels, Andrew Diaz, Tiffany A LaDow, Sarah Westbrook","doi":"10.24926/iip.v16i1.6368","DOIUrl":"10.24926/iip.v16i1.6368","url":null,"abstract":"<p><p><i>Purpose:</i> While there is evidence that pharmacist-led medication counseling improves patient safety and outcomes, there is conflicting evidence of the impact of pharmacy students on patient care outcomes. The objective of this study is to investigate if pharmacy student-led new-start anticoagulant medication counseling has a similar effect on healthcare utilization compared to pharmacist-led new start anticoagulant medication counseling. <i>Methods:</i> This study is a multicenter retrospective cohort study. The primary outcome is a composite of unplanned patient contact (phone call or MyChart message) with healthcare providers, emergency department (ED) visits, and hospital readmission within 30 days of discharge. Patients at least 18 years old that are newly started on apixaban, rivaroxaban, or warfarin for a new pulmonary embolism or deep vein thrombosis were included. Student- and pharmacist-led counseling data was collected from seven medical centers in central Texas between January 1, 2022 and June 30, 2023 via chart review on Epic. <i>Results:</i> There were 575 patients included in this study. Of these, 165 (29%) patients were counseled by students, 84 (15%) patients were counseled by pharmacists, and 326 (57%) patients were not counseled at all. 440 (77%) patients had unplanned patient contact, ED visit, and/or readmission within 30 days of discharge. There was no difference in all-cause (p = 0.78) or bleeding-related (p = 0.23) composite unplanned patient contact, ED visits, and readmissions within 30 days of discharge between student- and pharmacist-led counseling. <i>Conclusion:</i> This study suggests that student-led versus pharmacist-led anticoagulant counseling shows no difference in patient outcomes and healthcare utilization.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Forensic Cases to Introduce First Year Pharmacy Students to Forensic Pharmacy and Strengthen Student Learning in Basic Sciences.","authors":"Reza Karimi, Huy Hoang, Fawzy Elbarbry, Anita Cleven","doi":"10.24926/iip.v16i1.6312","DOIUrl":"10.24926/iip.v16i1.6312","url":null,"abstract":"<p><p><i>Description of the problem:</i> Forensic pharmacy is a scientific field in which trained forensic pharmacists apply their knowledge to assist law enforcement agencies in solving criminal cases. The role of forensic pharmacists is not emphasized in the pharmacy curriculum, and there is limited information about how faculty can introduce pharmacy students to this field. <i>The innovation:</i> A unique curricular activity was created to introduce first-year pharmacy students to the craft of forensic pharmacy and promote student learning of basic sciences. Thirteen teams (68 students total) participated in this activity. Each team watched an episode of a TV show, <i>Forensic Files</i>; prepared a report; and presented data covering factors contributing to the incident, safety measures, the roles a forensic pharmacist plays in various criminal cases, mechanisms of action, major toxicities, and indications for the drug or compound that contributed to the harm. <i>Critical analysis:</i> An anonymous survey tool was administered, with a 57% respondent rate, to assess the effectiveness of the activity. Approximately 70% of students agreed that the activity strengthened their knowledge in basic sciences, 75% agreed it promoted presentation and critical-thinking skills, and 80% agreed that the activity encouraged teamwork and self-directed learning. In addition, the activity promoted the six levels of Bloom's taxonomy to support student learning. <i>Next steps:</i> Faculty can generate elective courses to introduce pharmacy students to forensic pharmacy and use real-life forensic cases to strengthen student learning.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Expanded Pharmacist Prescriptive Authority on COVID-19 Vaccine Rates.","authors":"Taylor Le, Thomas Kelly","doi":"10.24926/iip.v16i1.6126","DOIUrl":"10.24926/iip.v16i1.6126","url":null,"abstract":"<p><p><i>Background</i>: Recent legislatures have granted expanded prescriptive authority to pharmacists with a collaborative practice agreement with a physician. This authority could include prescribing tobacco cessation products, birth controls, and antivirals for COVID-19. Although closely associated with providing preventative measures for COVID-19 in the forms of testing and vaccinations, the relationship between pharmacist prescriptive power and rate of COVID-19 vaccination remains unexplored. The objective of the study is to determine the association between pharmacist prescriptive authority and the rate of COVID-19 vaccinations between neighboring counties along state lines of states with differing laws on this prescriptive power. <i>Methods</i>: States with expanded pharmacist prescriptive authority include: New Mexico, Oregon, Idaho, Florida, California, North Carolina, Montana, New York, Iowa, Massachusetts, and Ohio. Counties are selected if the center of the county is within 30 miles from a state border that divides a state with expanded pharmacist prescriptive authority from a state without. Monthly vaccination data from January 2021 to December 2021 was acquired from the Centers for Disease Control and Prevention and linear regression was performed and state-border-pair fixed effects was used as a control. <i>Results</i>: The estimated effect of expanded prescriptive authority is an increase of five percentage points in the share of the adult population that completed the initial COVID-19 vaccine series. <i>Conclusion</i>: The relationship between pharmacist prescriptive authority and increased COVID-19 vaccination rates is statistically significant. The results showed that allowing pharmacist to have prescriptive powers could potentially aid in reducing vaccine hesitancy for future pandemics.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509719/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influenza Vaccination Rates, Perceptions, and Vaccine Hesitancy in K-12 Teachers and Staff.","authors":"Kevin Cleveland, Kathy Eroschenko, Dalys Davenport, Elaine Nguyen","doi":"10.24926/iip.v16i1.6302","DOIUrl":"10.24926/iip.v16i1.6302","url":null,"abstract":"<p><p><i>BACKGROUND:</i> Vaccination misinformation can contribute to vaccine hesitancy and decreased vaccination. Previous influenza immunization events at various K-12 schools carried out by Idaho State University L.S. Skaggs College of Pharmacy have noticed a small turn out of teachers and staff getting immunized during these events. Given the prominent role that teachers/staff serve in communities, we surveyed K-12 teachers and staff to determine their perceptions, knowledge, and reasons surrounding vaccine hesitancy. Our survey focused on the influenza vaccine, but also inquired about vaccine knowledge in general. <i>METHODS:</i> A Qualtrics survey was distributed online throughout the West Ada School District, located in southwestern Idaho. Demographics, receipt of influenza vaccine, vaccination motivation, knowledge and reasons for hesitancy were collected. Surveys were distributed July 2020 and analyzed using descriptive statistics. Response differences between those who most recently received their influenza vaccine and those who did not were also compared using chi-square or Mann-Whitney U tests when appropriate. RESULTS: A total of 503 surveys were completed, with all respondents teaching throughout the K-12 curriculum. A majority of respondents (n=409;81%) received a yearly influenza vaccination. Reasons for vaccination included: avoidance of flu, reduction of spread, and prevention of complications. Reasons against vaccination included: lack of efficacy, side effects, and numerous \"other\" responses. When comparing general influenza vaccine knowledge between those who received their influenza vaccine vs. those that did not, those who had been vaccinated displayed responses that more closely coincided with scientific data. <i>CONCLUSIONS:</i> The majority of surveyed K-12 teachers/staff received their influenza vaccine during the 2019-2020 season. However, ~20% of teachers/staff are still hesitant due to misinformation regarding vaccinations. Resources and partnerships between health organizations and school districts may increase vaccine acceptance.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Effect on Total Daily Insulin Dose in Adult Patients with Type 1 Diabetes Managed with Metformin and/or GLP-1 or GLP-1/GIP Receptor Agonists.","authors":"Mayeesha Ahmed, Emily Pierson, Molly Webster","doi":"10.24926/iip.v16i1.6450","DOIUrl":"10.24926/iip.v16i1.6450","url":null,"abstract":"<p><p><i>Purpose</i>: There are few studies that have assessed the utility of metformin and glucagon-like peptide-1 receptor agonists (GLP-1 RA) in type 1 diabetes (T1D), specifically looking at glucose control indices. These studies have largely evaluated the impact of agents within the class that are not routinely used. Limited data exist on the use of the dual glucagon-like peptide-1/glucose-dependent insulinotropic polypeptide receptor agonist (GLP-1/GIP RA) in T1D. The objective of this study was to evaluate the effect of this growing practice in utilizing these common non-insulin therapies in T1D. <i>Methods</i>: This single-center, retrospective cohort study evaluated adult patients with T1D who received standard insulin therapy plus the following non-insulin therapies for at least 3 months: metformin; GLP-1 RA or GLP-1/GIP RA; or metformin and a GLP-1 RA or GLP-1/GIP RA (combination group). Data points were collected on starting dates of the first and second (if applicable) non-insulin agents, and the first office visit of at least 3 months on maximum tolerated doses. The primary endpoint was change in total daily insulin dose (TDD). Secondary and safety endpoints were evaluated in A1c, weight, and hypoglycemia. <i>Results</i>: A total of 110 of 366 patients met inclusion criteria. Changes in average insulin TDD were +4.06, -5.9 and -6.9 units for the metformin, GLP-1RA or GLP-1/GIP RA, and combination groups respectively (P =0.013). TDD after non-insulin therapy addition decreased in all patients on average 3.54 units (P =0.02). Non-insulin therapies showed a significant decrease in A1c by 0.62%, weight by 3.8kg, and hypoglycemia was seen in 76% of patients. <i>Conclusions</i>: Non-insulin therapies added to standard insulin therapy in T1D resulted in decreased insulin requirement, increased glycemic control, and decreased body weight. While statistically significant, it remains unclear if the decreased insulin requirement is clinically significant. Further prospective studies are warranted to validate these findings.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serial Blood Pressures Versus a Single Repeat Blood Pressure in a Family Medicine Clinic.","authors":"Ann M Philbrick, Caroline S Carlin, Christopher Fallert","doi":"10.24926/iip.v16i1.6438","DOIUrl":"10.24926/iip.v16i1.6438","url":null,"abstract":"<p><p><i>Purpose</i>. The best method to measure blood pressure (BP) in a clinic setting is debatable. This study was conducted to compare serial BPs to a single repeat BP after an initial elevated reading. <i>Methods</i>. For this quality improvement process, instead of obtaining a second BP measurement after an initially elevated BP, medical assistants (MA) obtained serial BP readings two minutes apart. Rooming BP was compared to the first serial BP reading (current process), and to the average of the last two BP readings. <i>Results</i>. Seventy-eight patients were included. The average rooming BP was 155.5 ± 15.3 mmHg systolic (mean ± standard deviation) and 88.7 ± 11.8 mmHg diastolic, which decreased to 146.05 ± 18.2 mmHg systolic and 85.7 ± 11.8 mmHg diastolic for the first BP and 147.5 ± 16.2 mmHg systolic and 86.9 ± 12.1 mmHg diastolic for the average BP. Compared to the rooming BP, both readings were significantly decreased (first BP: p<0.001 SBP, p=0.006 DBP; average BP: p<0.001 SBP, p=0.011 DBP), but results were not significant when first BP was compared to average BP (p=0.756 SBP, p=0.278 DBP). A total of 26.9% and 23.1% of patients reached a BP goal of <140/90 mmHg with the first BP (p<0.001), and average BP (p<0.001), respectively. <i>Conclusion</i>. In patients presenting to an outpatient clinic with an initial elevated BP reading, simply repeating a single BP measurement shortly after completing the rooming process resulted in significantly reduced BP readings, and was equal to obtaining serial readings. In a busy clinic or pharmacy setting, healthcare providers can be reasonably confident that a single repeat blood pressure is an accurate reflection of a patient's true BP.</p>","PeriodicalId":501014,"journal":{"name":"Innovations in pharmacy","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12509717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145282504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}