Ana González-Díaz, Cristina Canals-Garzón, Juan Gómez-Salgado, Nora Suleiman-Martos, José Luis Gómez-Urquiza
{"title":"[Therapeutic play as a strategy to reduce pain and anxiety in pediatric emergency care].","authors":"Ana González-Díaz, Cristina Canals-Garzón, Juan Gómez-Salgado, Nora Suleiman-Martos, José Luis Gómez-Urquiza","doi":"10.23938/ASSN.1142","DOIUrl":"https://doi.org/10.23938/ASSN.1142","url":null,"abstract":"","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"48 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Musculoskeletal pain and health-related quality of life in Spanish health sciences university students.","authors":"Beatriz Rodríguez-Romero, Lucía López-López, Inés Fernández-Fraga, Sonia Pértega Díaz","doi":"10.23938/ASSN.1115","DOIUrl":"https://doi.org/10.23938/ASSN.1115","url":null,"abstract":"<p><strong>Background: </strong>University students are not exempt from physical and mental health problems. This study aimed to analyze the prevalence of musculoskeletal pain, central sensitization, health-related quality of life, and associated factors among health sciences students.</p><p><strong>Methods: </strong>Cross-sectional study conducted in Spanish health sciences students using anonymous, self-administered questionnaires. Data included sociodemographic characteristics of participants, health-related quality of life (SF-12), frequency and location of musculoskeletal pain (Nordic Musculoskeletal Questionnaire, Numeric Pain Rating Scale), and central sensitization (Central Sensitization Inventory, CSI). Factors associated with the SF-12 physical and mental component summaries (PCS and MCS) were identified using multiple lineal regression analysis.</p><p><strong>Results: </strong>Of the 338 participants, 76.3% were female. A high prevalence of musculoskeletal pain was observed, particularly in the back region (e.g., 59% reported neck pain in the past month), with higher frequency in women. The mean PCS exceeded the Spanish adult population mean for both sexes (54.6 vs. 55.9; p =0.02), whereas the mean MCS was lower than the population mean (36.7 vs. 42.8; p <0.001), even after comparing them with age- and sex-matched population standardized scores. Female sex, disability, chronic musculoskeletal pain, and CSI = 40 were associated with poorer physical health, while only CSI scores were associated with poorer mental health.</p><p><strong>Conclusions: </strong>Health sciences students show a high prevalence of musculoskeletal pain and significant deterioration in mental health. Central sensitization is strongly linked to worse outcomes. Women have poorer mental health and greater prevalence, severity, and chronification of musculoskeletal pain.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"48 3","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Noelia Vera-Punzano, Ana Navascués, Leticia Armendáriz, Natividad Viguria, Mercedes Herranz-Aguirre, Manuel García Cenoz, Camino Trobajo-Sanmartín, Aitziber Echeverria, Iván Martínez-Baz, Carmen Ezpeleta, Guillermo Ezpeleta, Jesús Castilla
{"title":"[Nirsevimab immunization effectiveness against respiratory syncytial virus hospitalization in newborns: two season of use in Navarre, Spain].","authors":"Noelia Vera-Punzano, Ana Navascués, Leticia Armendáriz, Natividad Viguria, Mercedes Herranz-Aguirre, Manuel García Cenoz, Camino Trobajo-Sanmartín, Aitziber Echeverria, Iván Martínez-Baz, Carmen Ezpeleta, Guillermo Ezpeleta, Jesús Castilla","doi":"10.23938/ASSN.1133","DOIUrl":"10.23938/ASSN.1133","url":null,"abstract":"<p><strong>Background: </strong>Respiratory syncytial virus (RSV) is the leading cause of infant hospitalisation. In 2022, nirsevimab was approved in the European Union to prevent severe respiratory disease due to RSV during the first year of life. Our aim is to evaluate the effectiveness of nirsevimab immunoprophylaxis in new-borns for preventing RSV -related hospitalisations in Navarre, Spain, during its first two seasons of use.</p><p><strong>Methods: </strong>Nirsevimab was offered free of charge to infants born from October to December 2023 and from September to December 2024. Each cohort was followed until February of the following year. Cases were infants hospitalised for PCR-confirmed RSV infection. Cox regression was used to estimate the hazard ratio of hospitalisation for immunised versus non-immunised children.</p><p><strong>Results: </strong>Nirsevimab was offered to 2,699 new-borns; of them, 2,541 (94.1%) received nirsevimab. In the 2023-2024 season, 17 RSV-related hospitalisations were recorded and 24 in the 2024-2025 season. The average risk of RSV hospitalisation was 7.6% in non-immunised new-borns versus 1.1% in immunised ones. Overall, effectiveness of nirsevimab was 79.5% (95% CI: 59.2 - 89.7), with estimates of 89.9% in 2023-2024 and 52.8% in 2024-2025, with no significant differences between seasons (p=0.055). On average, one RSV hospitalisation was prevented per 22.6 immunised infants.</p><p><strong>Conclusions: </strong>Nirsevimab immunoprophylaxis substantially reduces RSV hospitalisations, helping ease paediatric hospital burden. However, as some immunised infants were still hospitalised, additional preventive measures remain necessary.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"48 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481417/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The importance of life stories in the care for a good death].","authors":"Geno Ochando Ortiz","doi":"10.23938/ASSN.1134","DOIUrl":"10.23938/ASSN.1134","url":null,"abstract":"","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"48 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eduardo Tejedor-Tejada, Jesús Miguel Tejedor Muñoz
{"title":"[Cannabinoid content in seized hashish joints from Castilla y León (Spain)].","authors":"Eduardo Tejedor-Tejada, Jesús Miguel Tejedor Muñoz","doi":"10.23938/ASSN.1126","DOIUrl":"10.23938/ASSN.1126","url":null,"abstract":"<p><strong>Background: </strong>Cannabis, in both its herbal form and resin-derived products, is the most widely consumed illicit drug worldwide. This study aimed to determine the potency and dosage of the primary cannabinoids present in cannabis resin from joints circulating in the region.</p><p><strong>Methods: </strong>A descriptive study was conducted on seized joints confiscated by law enforcement agencies in the Autonomous Community of Castilla y León (Spain) between 2017 and 2020. Gross (whole joint) and net (filler) weights were recorded. Gas chromatography was used to quantify cannabinoids delta-9-tetrahydrocannabinol, cannabidiol, and cannabinol. Potency (percentage content) and dosage (mg) were calculated and bioavailability was estimated at 10% and 25%.</p><p><strong>Results: </strong>A total of 639 joints containing a mixture of cannabis resin and tobacco were analyzed (34.3% of confiscated samples). Both gross and net weights showed a decreasing trend over time (6.5-8.5%). Median potency values for delta-9-tetrahydrocannabinol, cannabidiol, and cannabinol were 7.58%, 0.62%, and 0.60%, respectively, while corresponding dosages were 57.04 mg, 4.57 mg, and 4.46 mg. Overall potency and dosage declined across the study period for THC (13.5%), CBN (73%) and CBD (52-67%).</p><p><strong>Conclusions: </strong>The delta-9-tetrahydrocannabinol potency and dosage found in confiscated cannabis resin joints during the study period were higher than those typically reported for herbal cannabis joints, suggesting greater user exposure and increased potential health risks.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"48 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[May you benefit from what you see: A humanistic reflection on the palliative gaze].","authors":"Juan Luis Torres-Tenor","doi":"10.23938/ASSN.1130","DOIUrl":"10.23938/ASSN.1130","url":null,"abstract":"<p><p>This essay, written from the clinical experience of a physician specialized in palliative care, reflects on the need to reframe this discipline within both medical practice and social culture. Through a personal lens, and using the lyrics of Spanish singer-songwriter Joaquín Sabina as a guiding thread, it argues that institutional and emotional resistance to palliative care - palliphobia - arises not only from structural barriers, but also from a medical narrative focused almost exclusively on cure. The text underscores the essential role of healthcare professionals in fostering this paradigm shift and the importance of reclaiming person-centered care: a way of seeing, listening, and accompanying, even when cure is no longer possible. Against the backdrop of technological noise and clinical haste, the essay proposes refining our gaze so that, on both sides of the consultation desk, we may rediscover meaning and value in what we see.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"48 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Estefany Romero-Freile, Darwin Ortiz-Cerchar, David A Hernández-Páez, Ornella Fiorillo-Moreno, Yelson Alejandro Picón-Jaimes, Tulia Beltrán-Venegas, Johana Galván-Barrios, Ivan David Lozada-Martinez
{"title":"Six Sigma research in healthcare is associated with global health, research and development indicators: A scientometrics study based on countries by income groups.","authors":"Estefany Romero-Freile, Darwin Ortiz-Cerchar, David A Hernández-Páez, Ornella Fiorillo-Moreno, Yelson Alejandro Picón-Jaimes, Tulia Beltrán-Venegas, Johana Galván-Barrios, Ivan David Lozada-Martinez","doi":"10.23938/ASSN.1124","DOIUrl":"10.23938/ASSN.1124","url":null,"abstract":"<p><strong>Background: </strong>Six Sigma is widely implemented in healthcare to enhance efficiency, minimize medical errors, and improve patient safety. However, the global distribution and impact of Six Sigma research in healthcare remain underexplored. This study conducts a scientometrics analysis of Six Sigma research in healthcare, examining its association with global health, research, and development indicators across income groups.</p><p><strong>Methodology: </strong>A mixed-methods scientometrics study was employed, utilizing data from Scopus, PubMed, and other databases. Regression models and meta-analyses were applied to evaluate associations between Six Sigma research productivity and global health, research and development indicators. Publications were categorized by World Bank income groups, and bibliometric parameters such as impact were analysed.</p><p><strong>Results: </strong>A total of 804 Six Sigma-related publications in healthcare were identified, with high-income countries contributing 70.8% of the total output. The number of publications was significantly associated with adult mortality reduction in high- and upper-middle income countries (p <0.01). Research and development expenditure showed a strong positive correlation with Six Sigma research output across all income groups. However, low-income countries exhibited minimal research activity, with no significant associations detected.</p><p><strong>Conclusions: </strong>Six Sigma research in healthcare is predominantly concentrated in high-income countries, with increasing but uneven growth in upper-middle and low-middle income countries. The limited engagement of low-income countries underscores a critical research gap.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"48 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145002449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Coro Velasco Gametxogoikoetxea, Irene Fernández De Los Reyes, Fermín Jiménez Bermejo
{"title":"Isolated splenic sarcoidosis: A case report.","authors":"Coro Velasco Gametxogoikoetxea, Irene Fernández De Los Reyes, Fermín Jiménez Bermejo","doi":"10.23938/ASSN.1131","DOIUrl":"10.23938/ASSN.1131","url":null,"abstract":"<p><p>Isolated splenic sarcoidosis is a rare entity, but clinicians should consider it in patients with compatible clinical features. Its diagnosis is challenging due to the broad differential diagnosis, which includes hematologic and splenic neoplasms, infiltrative and inflammatory disorders, autoimmune diseases, and infections. We report the case of a 15-year-old female diagnosed with isolated splenic sarcoidosis during hospitalization for fever of unknown origin. Histopathological examination revealed non-caseating granulomas and necrotizing granulomas. The patient showed marked clinical and radiological improvement following corticosteroid therapy, supporting the diagnosis. Despite its atypical presentation, this case highlights the importance of including sarcoidosis in the diagnostic evaluation of prolonged fever, even in young patients without respiratory symptoms.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"48 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sixtina Perarnau-Pauner, Carmen Gomar-Sancho, Tània Estapé-Madinabeitia, Marina Mateu-Capell
{"title":"[Quality of process records in the surgical area and possible consequences for patient safety].","authors":"Sixtina Perarnau-Pauner, Carmen Gomar-Sancho, Tània Estapé-Madinabeitia, Marina Mateu-Capell","doi":"10.23938/ASSN.1120","DOIUrl":"10.23938/ASSN.1120","url":null,"abstract":"<p><strong>Background: </strong>The objective is to detect defects in the completion of surgical records (omissions/illegibility), assess their severity and potential consequences, and design improvement strategies.</p><p><strong>Methods: </strong>The clinical records of nursing and anaesthesia (paper-based) and surgical records (electronic) for major surgical procedures performed over a three-month period at Martorell Hospital (Spain) were reviewed. Deficiencies (omissions and illegibility) were identified, and variables with completion deficiencies in more than 50% of the records or with potential impact on patient safety were selected. A panel of experts used a questionnaire to assess severity (high = 70-89%, very high = >90%) and possible consequences (pre-, intra-, post-surgical, and administrative), and proposed for improvement measures.</p><p><strong>Results: </strong>Medical records from 491 patients were analysed. Illegibility was almost non-existent, except for four variables (=10%). The overall completion rate was 98%. Forty-three variables with defects in >50% of records or with potential impact were included in the questionnaire, which was sent to 29 experts. The reliability of their responses was very high (a=0.995; intraclass correlation coefficients: individual=0.880 and average=0.995). Omissions of nearly all variables were considered of high or very high severity, with postoperative consequences outweighing intraoperative ones. Face-to-face team training and record adaptation were the most frequently recommended improvement strategies.</p><p><strong>Conclusions: </strong>Surgical records show serious to very serious omissions with potential postoperative consequences for patient safety. Simulation-based training was considered the most effective tool for improvement.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"48 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476199/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abel Alejandro Sanabria Sanchinel, Byron Daniel Bol Marroquín
{"title":"[Clinical response to brivaracetam in two cases of drug-resistant juvenile absence epilepsy].","authors":"Abel Alejandro Sanabria Sanchinel, Byron Daniel Bol Marroquín","doi":"10.23938/ASSN.1132","DOIUrl":"10.23938/ASSN.1132","url":null,"abstract":"<p><p>Although only around 20% of individuals with idiopathic generalized epilepsy are drug-resistant, this minority presents a significant therapeutic challenge due to the limited number of approved medications for this condition. For absence seizures, only valproic acid and ethosuximide are approved by both the U.S. Food and Drug administration and the European Medicines Agency, with lamotrigine additionally approved by the European Medicines Agency. Evidence supporting the use of levetiracetam in this seizure type is limited, and brivaracetam has not yet been approved for generalized epilepsy. We report two cases of juvenile absence epilepsy in women with incomplete response and intolerance to first-line treatments, who demonstrated marked clinical improvement following treatment with brivaracetam.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"48 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12481415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}