Beatriz Heras Cazorla, Jorge Bedia García, Irene Gómez Gregoris, Miguel Víctor Grijalba Uche, Pablo Crespo Escudero
{"title":"[Parapharyngeal abscess caused by a foreign body in a paediatric patient: A case report and literature review].","authors":"Beatriz Heras Cazorla, Jorge Bedia García, Irene Gómez Gregoris, Miguel Víctor Grijalba Uche, Pablo Crespo Escudero","doi":"10.23938/ASSN.1172","DOIUrl":"10.23938/ASSN.1172","url":null,"abstract":"<p><p>Deep neck infections in pediatric patients are increasingly frequent and may lead to severe complications due to nonspecific early symptoms. We report the case of a 12-month-old infant who developed a parapharyngeal abscess with mediastinal extension following accidental fish bone ingestion, requiring combined surgical and conservative management with favorable outcome. The primary aim of this article is to present a representative clinical case to describe clinical presentation, physical examination, diagnostic evaluation, treatment, clinical course, and follow-up of this condition. Additionally, this study reviews the available literature to compare different diagnostic and therapeutic approaches and contrast them with our clinical practice, providing practical guidance to support the management of similar cases in the future.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13548294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148763083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aurora López-Llames, Paula Hernández-Ruiz, Vicente García-Román, Elena Ronda-Perez
{"title":"[Patient-reported reasons for missed otolaryngology outpatient appointments].","authors":"Aurora López-Llames, Paula Hernández-Ruiz, Vicente García-Román, Elena Ronda-Perez","doi":"10.23938/ASSN.1166","DOIUrl":"10.23938/ASSN.1166","url":null,"abstract":"<p><strong>Background: </strong>Non-attendance at hospital outpatient clinics disrupts continuity of care and reduces healthcare efficiency, particularly in high-demand specialties. This study analyzes patient-reported reasons for non-attendance at otolaryngology (ENT) outpatient clinics, classifies them according to their potential avoidability, and assesses the frequency of subsequent appointment rescheduling.</p><p><strong>Methods: </strong>A retrospective observational study was conducted at a secondary-level public hospital. Among 1,117 missed outpatient appointments recorded in 2024, a random sample of 299 was selected. Structured telephone interviews were carried out between February and June 2025. Reasons for non-attendance were categorized using a predefined classification and grouped as avoidable or unavoidable. Descriptive analyses were performed, together with ?² and Mann-Whitney U tests. Open-ended responses underwent descriptive thematic analysis and were mapped to the dimensions of Levesque's access-to-care framework.</p><p><strong>Results: </strong>The final analyses included 232 appointments (77.5%). Failure to receive appointment notification was the most frequently reported reason for non-attendance (32.3%), followed by work-related or personal scheduling conflicts (19.4%). Overall, 42.2% of missed appointments were considered potentially avoidable, whereas only 25.0% of them were subsequently rescheduled. Neither avoidability nor rescheduing was associated with age, sex, or nationality. The approachability dimension accounted for 44.6% of all reported reasons.</p><p><strong>Conclusions: </strong>Non-attendance at ENT outpatient clinics is largely attributable to potentially modifiable factors, particularly failures in the appointment notification process. Despite missed appointments, only one quarter of patients subsequently rescheduled their appointment.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13548295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148760690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabel San Martín-Erice, Cristina García-Vivar, Sara Furtado-Eraso, Ibai Tamayo-Rodríguez, Leticia San Martín-Rodríguez, Nelia Soto-Ruiz, Paula Escalada-Hernández
{"title":"High-risk profiles for functional and cognitive decline following COVID-19 confinement in nursing home residents: A multicentre observational study","authors":"Isabel San Martín-Erice, Cristina García-Vivar, Sara Furtado-Eraso, Ibai Tamayo-Rodríguez, Leticia San Martín-Rodríguez, Nelia Soto-Ruiz, Paula Escalada-Hernández","doi":"10.23938/ASSN.1165","DOIUrl":"10.23938/ASSN.1165","url":null,"abstract":"<p><strong>Background: </strong>To examine changes in functional and cognitive status among nursing home residents following COVID-19 confinement and to identify personal and clinical resident characteristics associated with greater decline.</p><p><strong>Methods: </strong>A multicentre retrospective observational study was conducted in nursing homes in Navarra, Spain. Functional and cognitive status were assessed before and after the confinement using the Barthel Index (BI), Mini Cognitive Examination (MEC), and Global Deterioration Scale (GDS). Resident characteristics, nursing home characteristics, and the nursing diagnosis Disrupted Thought Processes were analysed. Univariate and multivariable linear mixed-effects models were used to identify factors associated with changes in BI, MEC, and GDS scores.</p><p><strong>Results: </strong>The final analytical sample comprised 178 residents. All three outcomes deteriorated significantly following confinement. Mean BI and MEC scores decreased by 5.0 and 2.0 points, respectively, whereas mean GDS scores increased by 0.24 points. In multivariable analyses, Disrupted Thought Processes was associated with greater cognitive decline measured by MEC (B = 1.29; 95% CI: 0.40-2.18; p = 0.005). Difficulties in instrumental activities of daily living were associated with greater deterioration in GDS (B = 0.19; 95% CI: 0.02-0.37; p = 0.030) and BI scores (B = 3.60; 95% CI: 0.01-7.19; p = 0.049). Male sex was associated with greater BI decline (B = 4.07; 95% CI: -7.68 to -0.45; p = 0.028).</p><p><strong>Conclusions: </strong>COVID-19 confinement associates with functional and cognitive decline among nursing home residents. Disrupted Thought Processes may be a useful clinical indicator for identifying residents at increased risk of cognitive deterioration during prolonged isolation.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alba Sánchez Valverde, Rocío Abarca Dotor, Carlos Lopez Muley, Ximena Soledad Samaniego Vasquez, Neus Parellada Esquius
{"title":"[Prevalence of cannabis use in Primary Care].","authors":"Alba Sánchez Valverde, Rocío Abarca Dotor, Carlos Lopez Muley, Ximena Soledad Samaniego Vasquez, Neus Parellada Esquius","doi":"10.23938/ASSN.1170","DOIUrl":"10.23938/ASSN.1170","url":null,"abstract":"<p><strong>Background: </strong>To estimate the prevalence of cannabis use among adults attending primary care, identify the age of initiation and associated sociodemographic characteristics, and describe patterns of dependence risk.</p><p><strong>Methods: </strong>A cross-sectional descriptive study was conducted in three primary healthcare centres in the Barcelona metropolitan area. Adults aged 18 - 45 years were selected by simple random sampling. Telephone interviews used cannabis related questions from the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST), validated by the World Health Organization. Cannabis use prevalence and dependence risk were analysed by sociodemographic characteristics using multiple logistic regression.</p><p><strong>Results: </strong>Of 237 individuals contacted, 221 participated (93.25%). Among the participants, 58.8% were women, with a mean age of 33.5 years (SD = 8.1). Overall, 53.4% had used cannabis at least once in their lifetime, with a mean age of initiation of 18.4 years (SD = 4.1). Among lifetime users, 25.4% had a moderate risk of dependence. After adjustment for age and socioeconomic status, cannabis use was more likely among men than women (OR = 2.11; 95% CI: 1.21-3.72). Overall, 22.9% had used cannabis within the previous three months, and 81.5% of these users had a moderate risk of dependence. Moderate dependence risk was more frequent with lower educational attainment.</p><p><strong>Conclusions: </strong>Cannabis use prevalence exceeded that reported in previous studies and was higher in men. One-quarter of lifetime cannabis users had a moderate risk of dependence according to the ASSIST, particularly those with lower educational attainment.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148586488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alicia Hernando Larroy, Alicia Frías Herrero, José Luis Peña Segura, Daniel Palanca Arias
{"title":"[Stroke mimic after wasp sting in a child with Charcot-Marie-Tooth neuropathy X type 1].","authors":"Alicia Hernando Larroy, Alicia Frías Herrero, José Luis Peña Segura, Daniel Palanca Arias","doi":"10.23938/ASSN.1157","DOIUrl":"10.23938/ASSN.1157","url":null,"abstract":"<p><p>Charcot-Marie-Tooth syndrome type X1 (CMTX1) is an inherited motor and sensory neuropathy caused by mutations in the GJB1 gene located in the X chromosome. Although uncommon, stroke-like episodes have been reported in patients with CMTX1, typically triggered by stress and characterized by distinctive magnetic resonance imaging findings with complete spontaneous resolution. We report the case of a 13-year-old boy with CMTX1 and no prior neurological symptoms who developed right hemiparesis, dysarthria, and facial deviation following a wasp sting. After activation of the stroke code, brain magnetic resonance revealed bilateral hyperintense lesions in the centrum semiovale without evidence of thrombosis. To our knowledge, this is the first paediatric case of CMTX1 in which an insect sting acted as a trigger, mimicking stroke. Prompt activation of stroke protocols and neuroimaging is essential to establish the diagnosis and exclude other conditions.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148538062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ramón Santonja Alarcón, Carlos González Guitián, Jose Tuells
{"title":"[The origins of smallpox vaccination in Navarre: The contribution of the physician Manuel Gil y Albéniz (1801-1836)].","authors":"Ramón Santonja Alarcón, Carlos González Guitián, Jose Tuells","doi":"10.23938/ASSN.1167","DOIUrl":"10.23938/ASSN.1167","url":null,"abstract":"<p><strong>Background: </strong>The introduction of smallpox vaccination in the early nineteenth century marked a major milestone in the history of public health in Spain. Although its early dissemination has been mainly studied from an institutional perspective, the contribution of local physicians to its implementation remains less well understood.</p><p><strong>Methods: </strong>Historical study based on documentary sources conducted using primary sources, including archival records, historical newspapers, and medical memoirs, together with relevant secondary literature. The study focuses on the career of the Navarrese physician Manuel Gil y Albéniz (1767-1849), who practised in the town of Cascante (Navarre).</p><p><strong>Results: </strong>Gil y Albéniz introduced smallpox vaccination in Cascante in 1801, during the early stage of its adoption in Spain. He carried out hundreds of vaccinations and played an important role in disseminating vaccine material throughout Navarre. His writings describe methods for preserving and transmitting vaccine material and document strategies that enabled vaccination to continue during the Peninsular War. He also participated in scientific networks as a corresponding member of the Royal Academy of Medicine of Barcelona (1803) and the Medical-Surgical Society of Cádiz (1820). His Colección de memorias médicas (1820) brings together his principal clinical observations.</p><p><strong>Conclusions: </strong>Manuel Gil y Albéniz was among the earliest physicians to introduce smallpox vaccination in Navarre. His career highlights the important contribution of local physicians in the dissemination of vaccination and the early development of public health in nineteenth-century Spain.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148538052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Subacute meningoencephalitis following intravesical BCG instillation immunotherapy].","authors":"Edurne Bidegain Garbala, Miren Arteaga Mazuelas, Vanesa Jarne Betrán, María Luisa Abínzano Guillén","doi":"10.23938/ASSN.1145","DOIUrl":"10.23938/ASSN.1145","url":null,"abstract":"<p><p>Intravesical instillation of Bacillus Calmette-Guérin (BCG), a live attenuated strain of Mycobacterium bovis, is the standard adjuvant treatment following transurethral resection of intermediate- and high-risk non-muscle-invasive urothelial carcinoma. Its therapeutic effect relies on intense local immune activation, reducing recurrence and progression rates and thereby improving patient outcomesand quality of life. Although generally well tolerated, both local and systemic infections and inflammatory complications may occur. We report a case of central nervous system BCG dissemination following intravesical BCG immunotherapy. The insidious onset and non-specific neurological manifestations complicated the diagnostic process and delayed the initiation of appropriate treatment. This case highlights the importance of thorough medical history assessment and maintaining a high index of suspicion in patients presenting neurological symptoms after intravesical BCG therapy.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13386459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148379315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arturo Gámiz Rejano, Ana Isabel Gago Sánchez, Rosa María Rodríguez Alonso
{"title":"[Treatment with dabrafenib and trametinib in an intrahepatic cholangiocarcinoma harboring a BRAF V600E mutation].","authors":"Arturo Gámiz Rejano, Ana Isabel Gago Sánchez, Rosa María Rodríguez Alonso","doi":"10.23938/ASSN.1159","DOIUrl":"10.23938/ASSN.1159","url":null,"abstract":"<p><p>Intrahepatic cholangiocarcinoma is a poor prognosis malignancy with limited therapeutic options in advanced stages. Identification of actionable molecular alterations may enable targeted therapies in selected patients. We describe a 74-year-old man with metastatic intrahepatic cholangiocarcinoma harboring a BRAF V600E mutation, treated off-label in the second-line setting with dabrafenib (150 mg twice daily) plus trametinib (2 mg once daily) after progression on platinum-based chemotherapy. Treatment resulted in stable disease, a reduction in CA 19-9, and mild adverse events. Progression-free survival was 12.8 months and overall survival reached 44.4 months. This case underscores the importance of early molecular profiling and supports the integration of targeted therapies into routine clinical practice for tumors with limited effective therapeutic options.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 2","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13386458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148321413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mateo Cacho Uzal, Juan Cueva Ares, Fe Lopez-Juiz, Francisco Reyes Santías
{"title":"[Efficiency after integrating a hospital with a 'new management model'].","authors":"Mateo Cacho Uzal, Juan Cueva Ares, Fe Lopez-Juiz, Francisco Reyes Santías","doi":"10.23938/ASSN.1162","DOIUrl":"10.23938/ASSN.1162","url":null,"abstract":"<p><strong>Background: </strong>This study evaluates the efficiency of a hospital under two management models, private (2015-2018) and public (2019-2022), and examines the impact of the COVID-19 pandemic (2020-2021).</p><p><strong>Methods: </strong>Hospital efficiency was evaluated using an output-oriented data envelopment analysis model with variable returns to scale. Outputs included consultations, emergency visits, surgical procedures, admissions, and inpatient stays, assuming a constant input (=1). Robustness was assessed using a parametric bootstrap (1,500 replications) to obtain bias-corrected efficiency scores and confidence intervals. An interrupted time series analysis was conducted to estimate a counterfactual scenario under continued private management and compare it with observed outcomes under public management.</p><p><strong>Results: </strong>Efficiency under private management remained consistently close to the frontier during 2015-2018. Under public management, efficiency declined sharply during the pandemic, reaching near-zero values in 2020-2021. Bootstrap results confirmed that these reductions were statistically significant and not random. A partial recovery was observed in 2022; however, efficiency remained below counterfactual projections.</p><p><strong>Conclusions: </strong>While efficiency performed stably under private management, the public model was markedly affected by the pandemic, though showing signs of resilience thereafter. These findings highlight the sensitivity of hospital efficiency to external crises and governance structures, underscoring the need to strengthen resilience, digitalization, and sustainability to maintain efficiency and equity in future health system disruptions.</p>","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13227081/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147794219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Anales del Sistema Sanitario de Navarra in 2025: Progress continues].","authors":"Pere Godoy, Carmen Beorlegui","doi":"10.23938/ASSN.1163","DOIUrl":"10.23938/ASSN.1163","url":null,"abstract":"","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13233062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147794223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}