Anales del sistema sanitario de Navarra最新文献_第3页

[Unequal impact of COVID-19 on mortality in long-term care homes across health areas of Castilla-La Mancha (Spain)]. [2019冠状病毒病对卡斯蒂利亚-拉曼恰（西班牙）各卫生地区长期护养院死亡率的不同影响]。

IF 0.6

Anales del sistema sanitario de Navarra Pub Date : 2026-04-22 DOI: 10.23938/ASSN.1160

María Victoria Zunzunegui Pastor, Iñaki Rubio Mengual, Álvaro Villar Baile, Fernando J García López

{"title":"[Unequal impact of COVID-19 on mortality in long-term care homes across health areas of Castilla-La Mancha (Spain)].","authors":"María Victoria Zunzunegui Pastor, Iñaki Rubio Mengual, Álvaro Villar Baile, Fernando J García López","doi":"10.23938/ASSN.1160","DOIUrl":"10.23938/ASSN.1160","url":null,"abstract":"Background: To assess whether inequalities existed across the eight health areas of Castilla-La Mancha (Spain) in all-cause and COVID-19 mortality in long-term care homes during 2020, and whether these differences were explained by COVID-19 incidence in the corresponding health areas.Methods: Data were obtained from the Castilla-La Mancha Transparency Portal. Care homes were classified by health area, size, ownership, and COVID-19 incidence at the health-area level. Poisson regression models were used to estimate risk ratios for all-cause and COVID-19 mortality in each health area, using Toledo as the reference, and adjusting for size, ownership, and health-area COVID-19 incidence.Results: Among 310 care homes (25,150 places), 4,460 deaths were recorded, including 2,821 attributed to COVID-19. All-cause mortality ranged from 7% in care homes in Talavera to 26% in those in Ciudad Real, while COVID-19 mortality ranged from 4% in care homes in Puertollano to 17% in care homes in Ciudad Real. In adjusted analyses, care homes in Ciudad Real, Guadalajara, Albacete, and Puertollano had higher all-cause mortality risk than those in Toledo, whereas those in Talavera showed lower risk. Only care homes in Albacete showed higher risk of COVID-19 mortality compared with those in Toledo.Conclusions: Substantial territorial inequalities in mortality risk are observed in long-term care homes in Castilla-La Mancha for 2020. These inequalities were only partially explained by the community incidence of COVID-19.","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13262767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147794176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Qualitative evaluation of a community intervention in educational centres: Opinion of the professionals involved. 对教育中心社区干预的定性评价：有关专业人员的意见。

IF 0.6

Anales del sistema sanitario de Navarra Pub Date : 2026-04-22 DOI: 10.23938/ASSN.1150

Maria Clara Vidal-Thomàs, Joana Ripoll Amengual, Maria Belén Cacereño Jiménez, Pau Sempere Andrés, Elisa Urbina Sampedro, Sebastiá March Llull

{"title":"Qualitative evaluation of a community intervention in educational centres: Opinion of the professionals involved.","authors":"Maria Clara Vidal-Thomàs, Joana Ripoll Amengual, Maria Belén Cacereño Jiménez, Pau Sempere Andrés, Elisa Urbina Sampedro, Sebastiá March Llull","doi":"10.23938/ASSN.1150","DOIUrl":"10.23938/ASSN.1150","url":null,"abstract":"Background: Consulta Joven is a community intervention developed in primary care to address adolescents´ health needs. It offers open health consultations in secondary schools within a context of trust and confidentiality and is complemented by additional health promotion activities. This study explores the perceptions of professionals involved in the programme regarding challenges and key elements influencing its implementation.Methods: A qualitative, descriptive-interpretive approach study was conducted in primary care in Mallorca (Spain) in 2017. Participants were recruited by Consulta Joven coordinators using purposive theoretical sampling. Three focus groups were conducted with ten nurses, four physicians, and six teachers. Two researchers independently coded transcripts using a general inductive approach. Categories were developed through content analysis and refined through team discussion.Results: Four categories emerged: Perceived value and usefulness of Consulta Joven, Barriers to implementation, Key elements for programme development, and Proposals for improvement. Participants described Consulta Joven as an effective strategy to reach adolescents, promote healthy behaviours, and identify health problems before they seek medical care. Trust and confidentiality are highlighted as essential for its success, along with intersectoral collaboration with community stakeholders. Conclusions, Professionals perceive Consulta Joven as a useful intervention to adolescent health promotion. Strengthening institutional support and collaboration between the health and education sectors, and introducing the programme at earlier educational stages, may enhance its preventive impact.","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13308354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147794204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discrimination of persons living with obesity by healthcare professionals. 保健专业人员对肥胖患者的歧视。

IF 0.6

Anales del sistema sanitario de Navarra Pub Date : 2026-04-20 DOI: 10.23938/ASSN.1161

José Ignacio Baile, María José González-Calderón, María Frenzi Rabito-Alcón

{"title":"Discrimination of persons living with obesity by healthcare professionals.","authors":"José Ignacio Baile, María José González-Calderón, María Frenzi Rabito-Alcón","doi":"10.23938/ASSN.1161","DOIUrl":"10.23938/ASSN.1161","url":null,"abstract":"Obesity is a highly prevalent and complex condition with biomedical, psychological, and social dimensions that pose major challenges for healthcare systems. Beyond its clinical consequences, people living with obesity frequently experience weight-based discrimination in healthcare settings, undermining care quality and equity. This paper examines key mechanisms underlying obesity-related stigma among healthcare professionals, including attribution of excess weight to individual responsibility and the internalization of stigma by patients. Drawing on current evidence, it analyses how negative attitudes of healthcare professionals contribute to suboptimal clinical interactions, inadequate care environments, and reduced patient engagement. These processes may weaken the therapeutic relationship, hinder treatment adherence, and negatively affect physical and mental health outcomes. Addressing obesity stigma requires targeted professional training, adaptation of care environments, and inclusive health policies to ensure equitable and respectful care for this population.","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13308369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147731050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phenotype of autosomal dominant Alport syndrome with a likely pathogenic heterozygous variant in the COL4A3 gene (Gly366Arg) and incidental teratozoospermia: A case report. 常染色体显性Alport综合征伴COL4A3基因（Gly366Arg）可能致病性杂合变异和偶发性畸形精子症的表型：1例报告。

IF 0.6

Anales del sistema sanitario de Navarra Pub Date : 2026-04-20 DOI: 10.23938/ASSN.1158

Vicente Martín Moreno, Amanda Martín Fernández, Asunción García Mateos, Jorge Hurtado Gallar, Cristina Angulo García, Raquel Sánchez-Redondo Mayordomo

{"title":"Phenotype of autosomal dominant Alport syndrome with a likely pathogenic heterozygous variant in the COL4A3 gene (Gly366Arg) and incidental teratozoospermia: A case report.","authors":"Vicente Martín Moreno, Amanda Martín Fernández, Asunción García Mateos, Jorge Hurtado Gallar, Cristina Angulo García, Raquel Sánchez-Redondo Mayordomo","doi":"10.23938/ASSN.1158","DOIUrl":"10.23938/ASSN.1158","url":null,"abstract":"Autosomal dominant Alport syndrome (ADAS) is the least common form of Alport syndrome, the second most common monogenic cause of chronic kidney disease after autosomal dominant polycystic kidney disease. We report a 14-year follow-up of a patient with ADAS carrying a likely pathogenic heterozygous variant in COL4A3 (Gly366Arg substitution). The disease initially presented with microhematuria and no renal impairment on analysis or ultrasound. The patient progressively developed bilateral renal cysts and renal failure -a classic renal pattern of the syndrome- and bilateral hearing loss. Incidentally, infertility study (had not children) showed teratozoospermia and elevated levels of luteinizing hormone and progesterone, hormones associated with spermatogenesis. Long-term follow-up of rare variants of Alport syndrome helps refine genotype-phenotype correlations and disease progression. The incidental finding of teratozoospermia raises the possibility of an etiological association, that warrants further investigation as a3(IV) collagen chains involved in spermatogenesis are present in seminiferous tubules.","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13229524/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147725451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Achievement of pharmacokinetic/pharmacodynamic targets with linezolid therapeutic drug monitoring in critically ill patients]. [利奈唑胺治疗药物监测危重患者药代动力学/药效学目标的实现]。

IF 0.6

Anales del sistema sanitario de Navarra Pub Date : 2026-03-31 DOI: 10.23938/ASSN.1151

Irati Irigoyen Rodriguez, Leire Leache, Julen Fernández-González, Amaia Egües, Julián Librero López

{"title":"[Achievement of pharmacokinetic/pharmacodynamic targets with linezolid therapeutic drug monitoring in critically ill patients].","authors":"Irati Irigoyen Rodriguez, Leire Leache, Julen Fernández-González, Amaia Egües, Julián Librero López","doi":"10.23938/ASSN.1151","DOIUrl":"10.23938/ASSN.1151","url":null,"abstract":"Background: Standard dosing of linezolid regimen frequently results in suboptimal exposure in critically ill patients. This study aimed to analyze the association between dosing regimens (total daily dose and infusion duration) and the probability of achieving pharmacokinetic/pharmacodynamic targets, as well as their microbiological and clinical impact.Methods: A retrospective observational study was conducted in critically ill patients admitted to intensive care units who underwent therapeutic drug monitoring of linezolid between May 2021 and December 2023. Achievement of pharmacokinetic/pharmacodynamic targets (Cmin: 2-7 mg/L, AUC: 0-24/MIC: 80-120 mg*h/L, and T>MIC =85%) was evaluated according to the initial regimens (1,200 or 1,800 mg/day) and infusion duration (1 or 3 hours). Risk subgroups included obesity, augmented creatinine clearance, renal replacement therapy, and age <65 years.Results: Seventy patients were included. At the first monitoring, only 18.6% achieved all three pharmacokinetic/pharmacodynamic targets and 40% achieved the Cmin target. No statistically significant differences were observed in target attainment according to dose or infusion duration, including within risk subgroups. However, the 1,800 mg/day regime showed a numerically higher proportion of patients achieving the Cmin target (54.5% vs. 37.3%). No significant differences in microbiological or clinical outcomes were observed between patients with Cmin within the target range and those outside it.Conclusions: Fewer than 20% of critically ill patients achieve all pharmacokinetic/pharmacodynamic targets with the initial regimen. These findings support the need for individualized dosing and therapeutic drug monitoring to optimize linezolid treatment in this population, particularly in high-risk patients.","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13131037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147583275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Technical quality of cardiopulmonary resuscitation after a training intervention and its association with anthropometric variables]. [训练干预后心肺复苏的技术质量及其与人体测量变量的关系]。

IF 0.6

Anales del sistema sanitario de Navarra Pub Date : 2026-03-31 DOI: 10.23938/ASSN.1156

David Peña-Otero, Pedro Gil-López, Miguel Ángel Iglesias-Blanco, Sergio Galarreta-Aperte, Piedad Gómez-Torres

{"title":"[Technical quality of cardiopulmonary resuscitation after a training intervention and its association with anthropometric variables].","authors":"David Peña-Otero, Pedro Gil-López, Miguel Ángel Iglesias-Blanco, Sergio Galarreta-Aperte, Piedad Gómez-Torres","doi":"10.23938/ASSN.1156","DOIUrl":"10.23938/ASSN.1156","url":null,"abstract":"Background: Owing to their capacity for rapid response, members of the Spanish Guardia Civil constitute a key resource for out-of-hospital cardiopulmonary resuscitation, particularly in rural or hard-to-reach areas. This study aimed to evaluate cardiopulmonary resuscitation technical quality following a training intervention and to examine its association with anthropometric variables.Methods: A quasi-experimental study with repeated measures and no control group was conducted in 41 members of the Rapid Intervention Section. Sociodemographic, anthropometric, and cardiopulmonary resuscitation quality variables were collected, including a composite total score (0-100 points) derived from compression quality, chest compression fraction, and ventilation performance. The simulation-based intervention, performed using a manikin, followed European Resuscitation Council guidelines.Results: Only one participant was a woman. Median BMI was 27.4 kg/m², and 70.7% of participants had a body fat percentage =25%. Post-intervention, significant improvements were observed in median total score (64 to 93 points), proportion of correct ventilations (33% to 90%), compression/ventilation ratio (12.2% to 46.3%), and mean compression rate (134 to 109/min). Height was negatively associated with post-intervention performance (ß = -1.024; p = 0.001).Conclusions: The training intervention significantly improved cardiopulmonary resuscitation quality. Height was inversely associated with performance, whereas body fat percentage showed no significant association. These findings should be interpreted with caution given the study design limitations.","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13137758/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147583210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful dissolution of a giant bezoar after enzyme complex therapy 用酶复合物处理后，一个巨大的甜菜成功溶解。

IF 0.6

Anales del sistema sanitario de Navarra Pub Date : 2026-03-09 DOI: 10.23938/ASSN.1154

Lucas Sabatella, Juan José Gascón Jiménez, Nuria Blanco, Fernando Rotellar, Víctor Valentí

引用次数: 0

[Knowledge of first aid for epileptic seizures among the general population and relatives of patients with epilepsy]. [普通人群和癫痫患者亲属对癫痫发作的急救知识]。

IF 0.6

Anales del sistema sanitario de Navarra Pub Date : 2026-03-06 DOI: 10.23938/ASSN.1147

Alejandro Viloria-Alebesque, Ángela Bono-Velilla, Elena Bellosta-Diago, María Pilar Navarro-Pérez, Nuria Reyes-Perera, Sonia Santos-Lasaosa

{"title":"[Knowledge of first aid for epileptic seizures among the general population and relatives of patients with epilepsy].","authors":"Alejandro Viloria-Alebesque, Ángela Bono-Velilla, Elena Bellosta-Diago, María Pilar Navarro-Pérez, Nuria Reyes-Perera, Sonia Santos-Lasaosa","doi":"10.23938/ASSN.1147","DOIUrl":"10.23938/ASSN.1147","url":null,"abstract":"Background: Epileptic seizures are typically paroxysmal and self-limiting events that are frequently witnessed and managed by laypersons. This study aimed to assess knowledge of first aid for epileptic seizures in two groups: the general population and relatives of patients with epilepsy.Methods: A structured survey was administered to members of the general population and to family members of patients with epilepsy. The questionnaire assessed knowledge of appropriate management and first aid maneuvers during a seizure. It included 16 questions: one open-ended item, eight multiple-choice questions, and seven additional questions directed specifically to family members.Results: Of the 434 respondents, 39.2% were family members of patients with epilepsy. Appropriate measures - such as remaining with the patient, timing the seizure, and cleaning secretions - were reported significantly more often by family members. Inappropriate actions - including placing objects in the patient´s mouth and restraining movements - were more common among the general population. No significant differences were observed regarding patient positioning. Family members most frequently identified healthcare professionals as their primary source of information, whereas the general population cited social media and mass media. Among family members, 51.1% would not administer medication; 62% would call emergency services in specific situations, and 54.5% would do so if the seizure lasted more than five minutes.Conclusions: Knowledge of seizure first aid was suboptimal in both groups, particularly in the general population. Targeted education strategies are needed to improve first aid training for both relatives and the broader community.","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[A case report of severe hypocalcemia secondary to Fahr's syndrome]. [Fahr综合征继发严重低钙血症1例报道]。

IF 0.6

Anales del sistema sanitario de Navarra Pub Date : 2026-02-18 DOI: 10.23938/ASSN.1138

Miren Vallejo Ruiz, Inés Moral Presa

{"title":"[A case report of severe hypocalcemia secondary to Fahr's syndrome].","authors":"Miren Vallejo Ruiz, Inés Moral Presa","doi":"10.23938/ASSN.1138","DOIUrl":"10.23938/ASSN.1138","url":null,"abstract":"Fahr's syndrome is a rare neurological disease characterized by bilateral intracranial calcifications associated with disturbances in calcium-phosphate metabolism, most commonly due to hypoparathyroidism. We report a 56-year-old man presenting with generalized seizures and behavioral changes. Laboratory evaluation revealed severe hypocalcemia, hyperphosphatemia, and low parathyroid hormone levels. Brain computed tomography demonstrated symmetrical calcifications involving the basal ganglia and other subcortical structures, consistent with Fahr's syndrome. Diagnosis was established through the integration of clinical features, biochemical abnormalities, and neurological findings, after excluding alternative causes of intracranial calcifications, including infectious, autoimmune, and genetic conditions. Management focused on prompt correction of hypocalcemia and long-term metabolic control with close biochemical monitoring. Early recognition of hypoparathyroidism is essential to prevent neurological complications and improve outcomes. This case highlights the pivotal role of laboratory assessment in the diagnosis and management of Fahr´s syndrome.","PeriodicalId":500996,"journal":{"name":"Anales del sistema sanitario de Navarra","volume":"49 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146215401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Fire management in hospitals: Structural limitations and operational solutions]. [医院消防管理：结构限制和操作解决方案]。

IF 0.6

Anales del sistema sanitario de Navarra Pub Date : 2026-02-17 DOI: 10.23938/ASSN.1155

Juan Carlos Camacho-Vega, Juan Gómez-Salgado, Javier Fagundo-Rivera

引用次数: 0