Journal of Research in Medical Sciences最新文献

{"title":"Evaluation of the new modified apnea test in confirmation of brain death.","authors":"Parviz Kashefi, Saeed Abbasi, Koosha Kiani, Maryam Khalifehsoltani Khajoei, Mojtaba Akbari","doi":"10.4103/jrms.jrms_913_22","DOIUrl":"https://doi.org/10.4103/jrms.jrms_913_22","url":null,"abstract":"<p><strong>Background: </strong>Apnea testing is mandatory to confirm brain death; however, it is unsafe for patients who have substantial hypoxemia without ventilator support. We used a new modified apnea test without the need to disconnect the patient from the ventilator in the present study and compared the outcomes and complications of the new method to the widely used old method.</p><p><strong>Materials and methods: </strong>The current study was conducted on people suspected of having brain death. Both the old and new apnea tests were carried out on the same individual. In the new modified method, instead of hyperventilating and then separating the brain death from the ventilator, the induced hypercapnia method was used, and instead of performing repeated arterial blood gas (ABG), the target ETCO₂ was obtained, and at the time of the target ETCO₂, ABG was also checked followed by comparing ETCO₂ with PaCO₂.</p><p><strong>Results: </strong>Thirty patients, including 25 (83.3%) males and 5 (16.75%) females, were included in the study. The results showed significant improvement in terms of O₂ saturation and heart rate (HR) using the new modified apnea test compared to the common test. Systolic blood pressure, diastolic blood pressure, and the frequency of complications were improved in the new modified test.</p><p><strong>Conclusion: </strong>The modified apnea test produced better results in terms of O₂ saturation, HR, and other clinical factors, while it does not require disconnection from the ventilator and repeated ABG assessment. Therefore, it can be used to successfully diagnose brain death in high-risk individuals suffering from severe hypoxia.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"29 ","pages":"48"},"PeriodicalIF":1.5,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of laparoscopic pneumoperitoneum on patient's respiratory variation of inferior vena cava and stroke volume index: A randomized controlled study.","authors":"Dawei Liu, Jingfei Sun, Kun Chen, Yanfeng Yao, Fan Zhang","doi":"10.4103/jrms.jrms_526_22","DOIUrl":"https://doi.org/10.4103/jrms.jrms_526_22","url":null,"abstract":"<p><strong>Background: </strong>The establishment of pneumoperitoneum has impacts on patient's cardiovascular function. In this study, the respiratory variation of inferior vena cava (IVC), stroke volume (SV) index, and other parameters was monitored to determine how the pneumoperitoneum affects the patient's hemodynamic and acknowledge how to resolve it.</p><p><strong>Materials and methods: </strong>Fifty-five patients were randomly divided into Group A (8 mmHg), Group B (10 mmHg), Group C (12 mmHg), Group D (14 mmHg), and Group E (12 mmHg, infusion with 7 mL/kg crystalloid solution). The parameters including IVC variability, SV index, mean artery pressure (MAP), heart rate (HR), cardiac output index (CI), and airway pressure were measured, to compare the changes before and after pneumoperitoneum.</p><p><strong>Results: </strong>Among Group A, Group B, Group C, and Group D, there were no significant differences in patients' prepneumoperitoneum information. Compare with prepneumoperitoneum, the difference in IVC variability, SV index, MAP, HR, CI, and airway pressure was statistically significant (<i>P</i> < 0.05). After the establishment of pneumoperitoneum, the difference in IVC variability, SV index, and airway pressure among Group A, Group B, Group C, and Group D was statistically significant (<i>P</i> < 0.05). Compare with Group C, the change rates of IVC variability, SV index, MAP, HR, and CI were smaller in Group E (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>The establishment of pneumoperitoneum could increase the patient's IVC variability and reduce SV index, and with the increase of pressure, IVC variability had an increasing trend, SV index had a decreasing trend. Fluid transfusion could reduce the relative influence of the pneumoperitoneum.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"29 ","pages":"46"},"PeriodicalIF":1.5,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The predictive value of neutrophil-lymphocyte ratio combined with the Global Registry of Acute Coronary Events score for inhospital adverse cardiovascular events in patients with acute ST-elevation myocardial infarction.","authors":"Caoyang Fang, Zhenfei Chen, Jing Zhang, Xiaoqin Jin, Mengsi Yang","doi":"10.4103/jrms.jrms_485_22","DOIUrl":"https://doi.org/10.4103/jrms.jrms_485_22","url":null,"abstract":"<p><strong>Background: </strong>The research explores the predictive efficacy of the neutrophil-to-lymphocyte ratio (NLR) in conjunction with the Global Registry of Acute Coronary Events (GRACEs) score for inhospital major adverse cardiovascular events (MACEs) among acute ST-segment elevation myocardial infarction (STEMI) subjects with primary percutaneous coronary intervention (PCI) history.</p><p><strong>Materials and methods: </strong>Patients were categorized into MACE (<i>n</i> = 58) and non-MACE cohorts (<i>n</i> = 184) based on MACE occurrence events during hospitalization. The predictive value of the NLR, GRACE score, and their combination for inhospital MACE events in STEMI subjects was assessed by the receiver operating characteristic curve (ROC).</p><p><strong>Results: </strong>NLR (8.99 [5.06, 12.01] vs. 5.15 [3.13, 7.66]) and GRACE scores (159.62 ± 43.39 vs. 116.96 ± 28.15) within MACE group notably surpassed the non-MACE group (<i>P</i> < 0.05). ROC curve analysis demonstrated that the area under the curve (AUC) for NLR in forecasting inhospital MACE events was 0. 72 (95% confidence interval [CI]: 0.645-0.795), with 0.655 sensitivity and 0.723 specificity, and optimal cutoff value as 7.01. The AUC for the GRACE score was 0.791 (95% CI: 0.717-0.865), with 0.862 sensitivity and 0.598 specificity, and the optimal cutoff value was 121.5. The combined AUC of NLR and GRACE score was 0.814 (95% CI: 0.745-0.884), with 0.707 sensitivity and 0.837 specificity.</p><p><strong>Conclusion: </strong>Both NLR and GRACE score independently predict inhospital MACE events in STEMI patients post-PCI. Integration of the NLR and GRACE score enhances accuracy in forecasting inhospital MACE event occurrences.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"29 ","pages":"41"},"PeriodicalIF":1.5,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992410/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regenerative mechanisms of stem cells and their clinical applications for degenerative eye diseases.","authors":"Baodong Zhang, Shusong Gao, Shibo Liu, Xuewu Gong, Jing Wu, Yu Zhang, Li Ma, Lijie Sheng","doi":"10.4103/jrms.jrms_358_23","DOIUrl":"https://doi.org/10.4103/jrms.jrms_358_23","url":null,"abstract":"<p><p>There are different types of treatment for eye diseases. Although the majority of eye diseases are curable with primary treatments and surgery, some of degenerative eye damages need regeneration that is not gained by conventional procedures. Stem cells, such as mesenchymal stem cells, human embryonic stem cell-derived retinal pigmented epithelium, and inducible pluripotent stem cells, are now considered one of the most important and safe methods for regeneration of various damaged tissues or organs. However, how will stem cell therapy contribute to regeneration and overcome degenerative eye diseases? This review discusses the regenerative mechanisms, clinical applications, and advantages of different types of stem cells for restoring degenerative eye diseases.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"29 ","pages":"42"},"PeriodicalIF":1.5,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992415/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of diagnostic performance between diffusion models parameters and mono-exponential apparent diffusion coefficient in patients with prostate cancer: A systematic review and meta-analysis.","authors":"Hamide Nematollahi, Mohammad Reza Maracy, Masoud Moslehi, Daryoush Shahbazi-Gahrouei","doi":"10.4103/jrms.jrms_359_23","DOIUrl":"https://doi.org/10.4103/jrms.jrms_359_23","url":null,"abstract":"<p><strong>Background: </strong>The importance of diffusion in prostate cancer (PCa) diagnosis has been widely proven. Several studies investigated diffusion models in PCa diagnosis.</p><p><strong>Materials and methods: </strong>This systematic review and meta-analysis study was performed to evaluate the ability of three diffusion models to diagnose PCa from the scientific electronic databases Embase, PubMed, Scopus, and Web of Science (ISI) for the period up to March 2022 to identify all relevant articles.</p><p><strong>Results: </strong>Eighteen studies were included in the systematic review section (7 diffusion kurtosis imaging [DKI] studies, 4 diffusion tensor imaging [DTI] studies, 4 intravoxel incoherent motion [IVIM] studies, and 3 IVIM-DKI studies). Pooled sensitivity, specificity, accuracy, and summary area under each diffusion model's curve (AUC) and 95% confidence intervals (CIs) were calculated. The pooled accuracy and 95% CI on detection (differentiation of tumor from normal tissue and benign prostatic hyperplasia/prostatitis) were obtained for apparent diffusion coefficient (ADC) at 87.97% (84.56%-91.38%) for DKI parameters (Gaussian diffusion [DK] 87.94% [78.71%-97.16%] and deviation from Gaussian diffusion [K] 86.84% [81.83%-91.85%]) and IVIM parameters (true molecular diffusion [DIVIM] 81.73% [72.54%-90.91%], perfusion-related diffusion [D*] 65% [48.47%-81.53%] and perfusion fraction [f] 80.36% [64.23%-96.48%]). The AUC values and 95% CI in the detection of PCa were obtained for ADC at 0.95 (0.92-0.97), for DKI parameters (DK 0.94 [0.89-0.99] and K 0.93 [0.90-0.96]) and for IVIM parameters (DIVIM 0.85 [0.80-0.91], D* 0.60 [0.43-0.77] and f 0.73 [0.63-0.84]). Two studies showed that the DTI accuracy values were 97.34% and 85%. For IVIM-kurtosis model in PCa detection, two studies stated that the DIVIM-K and KIVIM-K accuracy values were 85% and 84.44% (the pooled accuracy; 84.64% with 95% CI 75.78%-93.50%), and 72.50% and 71.11% (the pooled accuracy, 72.10% with 95% CI 64.73%-79.48%), respectively.</p><p><strong>Conclusion: </strong>Our findings showed that among the DKI, IVIM, and ADC parameters, it seems that ADC, Dk, DIVIM, and K are the most important, which can be used as an indicator to distinguish PCa from normal tissue. The DKI model probably has a higher ability to detect PCa from normal tissue than the IVIM model. DKI probably has the same diagnostic performance in PCa detection and grading compared to diffusion-weighted imaging and ADC.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"29 ","pages":"43"},"PeriodicalIF":1.5,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of preoperative frailty on perioperative neurocognitive disorders in elderly patients: A systematic review and meta-analysis.","authors":"Shan Zhao, Bei Wang, Meinv Liu, Dongdong Yu, Jianli Li","doi":"10.4103/jrms.jrms_694_23","DOIUrl":"https://doi.org/10.4103/jrms.jrms_694_23","url":null,"abstract":"<p><strong>Background: </strong>Perioperative neurocognitive disorders (PNDs) were the most common complication in elderly patients undergoing surgery. Early identification of risk factors for PNDs and implementation of preventive measures were critical to improve prognosis. We performed this systematic review and meta-analysis to explore the impact of preoperative frailty on PNDs in elderly surgical patients.</p><p><strong>Materials and methods: </strong>Systematic searches were performed in PubMed, Embase, and Web of Science. A fixed-effect model in RevMan5.3 software was conducted due to the low heterogeneity. The potential risk bias was assessed through Funnel plot and Egger's test. Sensitivity analysis was used to examine the robustness of the outcomes.</p><p><strong>Results: </strong>Sixteen cohort studies enrolling 4805 elderly patients were qualified for meta-analysis. Pooled results showed that preoperative frailty was linked to the development of PNDs (pooled odds ratio [OR]: 2.40, 95% confidence interval [CI]: 2.05-2.80, <i>P</i> < 0.001) without obvious heterogeneity (<i>P</i> = 0.19, <i>I</i> ² = 22%). Subgroup analyses revealed that the correlation between preoperative frailty and PNDs was more remarkable in prospective cohort studies (OR: 3.11, 95% CI: 2.47-3.91, <i>P</i> < 0.001) compared to retrospective cohort studies (OR: 1.94, 95% CI: 1.57-2.39, <i>P</i> < 0.001; test for subgroup difference, <i>P</i> = 0.003). In addition, the correlation in patients with cardiac surgery (OR: 3.38, 95% CI: 2.44-4.68, <i>P</i> < 0.001) was more noticeable than noncardiac surgery (OR: 2.17, 95% CI: 1.82-2.59, <i>P</i> < 0.001; test for subgroup difference <i>P</i> = 0.02).</p><p><strong>Conclusion: </strong>Our results demonstrated that preoperative frailty was independently associated with PNDs in geriatric patients undergoing elective surgery.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"29 ","pages":"47"},"PeriodicalIF":1.5,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression, anxiety, quality of life, and its relationship with some demographic characteristics of patients with lung neoplasm candidate for surgery.","authors":"Nasrin Masaeli, Gholamreza Kheirabadi, Setayesh Sindarreh, Hamid Talebzadeh, Atefeh Ebrahimzadeh, Mohammad Reza Maraci","doi":"10.4103/jrms.jrms_309_23","DOIUrl":"https://doi.org/10.4103/jrms.jrms_309_23","url":null,"abstract":"<p><strong>Background: </strong>In this study, we decided to investigate the state of depression, anxiety, and quality of life and its relationship with some demographic characteristics of lung neoplasm patients who were candidates for surgery.</p><p><strong>Materials and methods: </strong>In a cross-sectional study, all patients with lung neoplasm who were referred to medical centers affiliated to Isfahan University of Medical Sciences and were candidate for lung surgery in 2020-2021. Based on the inclusion and exclusion criteria, 52 people were assigned to the study consecutively. Then, the patients completed the demographic information questionnaire, the Hospital Anxiety and Depression Scale, and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (QLQ-C30) (EORTC QLQ-C30).</p><p><strong>Results: </strong>The score of depression and anxiety was normal (range 7-0) and the score of quality of life was in the relatively good range (50-175). As the patient's age increases (<i>P</i> = 0.014) and the duration of the disease increases (<i>P</i> = 0.041), the level of depression increases significantly. People with higher education had lower depression (<i>P</i> = 0.001) and anxiety (<i>P</i> = 0.003). People living in the city had a significantly better quality of life (<i>P</i> = 0.039). The higher the depression (<i>P</i> < 0.0001) and anxiety (<i>P</i> = 0.037) of the people, the lower the quality of life of the patients.</p><p><strong>Conclusion: </strong>As anxiety and depression increase, the quality of life of lung neoplasm patients decreases. Some demographic characteristics such as old age, insufficient education, rurality, and increased duration of the disease can be the risk factors for depression, anxiety, and reduced quality of life of patients with lung neoplasm.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"29 ","pages":"44"},"PeriodicalIF":1.5,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the effect of warmwater footbath with effleurage and petrissage massages on fatigue of patients undergoing hemodialysis.","authors":"Ardashir Afrasiabifar, Shekoofeh Hamzhiekia, Sima Mohammadhossini, Asadolah Mosavi","doi":"10.4103/jrms.jrms_418_22","DOIUrl":"https://doi.org/10.4103/jrms.jrms_418_22","url":null,"abstract":"<p><strong>Background: </strong>Few comparative studies have been carried out into the effects of nonpharmacological interventions on reducing fatigue in hemodialysis patients. This study compared the effect of warm footbath with effleurage and petrissage massages on fatigue in hemodialysis patients.</p><p><strong>Materials and methods: </strong>Seventy patients undergoing hemodialysis referring to two dialysis centers in 2016 were included in this clinical trial study. However, 62 hemodialysis patients finally completed the study. The patients were selected through a nonrandom sampling method, but were later assigned to one of the three groups of warmwater footbath, effleurage, and petrissage massages based on randomized blocked allocation. Using a multidimensional inventory, fatigue was assessed before the commencement of the interventions, at the end of the first and the 2^nd month of the interventions. The data were analyzed using statistical software of SPSS, version 25, through descriptive statistics by running median and Friedman tests with considering 95% confidence interval.</p><p><strong>Results: </strong>Warmwater footbath, effleurage, and petrissage resulted in a significant reduction or improvement in global fatigue and types of fatigue of patients undergoing hemodialysis at the end of the first and 2^nd month of the interventions (<i>P</i> = 0.001). The results of the between-groups comparison showed that there was no significant difference (<i>P</i> > 0.05) in fatigue reduction among the three groups of warmwater footbath, effleurage, and petrissage massages in terms of the median index of fatigue scores.</p><p><strong>Conclusion: </strong>Warmwater footbath, effleurage, and petrissage massages have similar positive effects on fatigue in patients undergoing hemodialysis.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"29 ","pages":"45"},"PeriodicalIF":1.5,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11992412/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of 5-year Survival of Elderly with Hypertension. A Prospective Cohort Study.","authors":"Fatemeh Naghdi Babaei, Ali Bijani, Seyed Reza Hosseini, Reza Ghadimi, Simin Mouodi","doi":"10.4103/jrms.jrms_859_22","DOIUrl":"10.4103/jrms.jrms_859_22","url":null,"abstract":"<p><strong>Background: </strong>Given the high prevalence of hypertension in older adults, this study was conducted to identify the factors affecting the 5-year survival of older people with hypertension.</p><p><strong>Materials and methods: </strong>In this cohort study, individuals aged 60 and over living in Amirkola, north of Iran who were diagnosed with hypertension were followed up for 5 years, and the effect of various factors on their survival was analyzed.</p><p><strong>Results: </strong>Among 1439 older people, 892 individuals (61.99%) had hypertension. Age (adjusted hazard ratio [aHR] =1.052, 95% confidence interval [CI] =1.019-1.086, <i>P</i> = 0.002), diabetes mellitus (aHR = 2.166, 95% CI = 1.398-3.354, <i>P</i> = 0.001), serum creatinine (aHR = 2.163, 95% CI = 1.391-3.363, <i>P</i> = 0.001), female gender (aHR = 0.460, 95% CI = 0.276-0.766, <i>P</i> = 0.003), body mass index ≥30 kg/m² (aHR = 0.386, 95% CI = 0.212-0.701, <i>P</i> = 0.002), physical activity score >150 (aHR = 0.382, 95% CI = 0.162-0.898, <i>P</i> = 0.027), each one unit increase of social support score (aHR = 0.914, 95% CI = 0.861-0.970, <i>P</i> = 0.003), and instrumental functional ability score (aHR = 0.907, 95% CI = 0.843-0.974, <i>P</i> = 0.009) showed a significant effect on 5-year survival of older people.</p><p><strong>Conclusion: </strong>Multiple factors (such as age, gender, social support, lifestyle behaviors, and comorbidities including diabetes mellitus and renal function) might predict the 5-year survival of the elderly with hypertension. They should be considered in health-care package of these patients.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"29 ","pages":"36"},"PeriodicalIF":1.5,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11376721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of phase angle with sarcopenia in patients undergoing maintenance hemodialysis: A case-control study.","authors":"Amirhesam Alirezaei, Amirhossein Miladipour, Navid Asgari, Marzieh Latifi, Seyed Amirhossein Fazeli","doi":"10.4103/jrms.jrms_38_24","DOIUrl":"10.4103/jrms.jrms_38_24","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia, characterized by reduced muscle strength and mass, is commonly observed in patients with kidney disease. This study aimed to investigate the factors that influence sarcopenia in patients undergoing maintenance hemodialysis (HD patients).</p><p><strong>Materials and methods: </strong>A case-control study was conducted from 2022 to 2023, involving a total of 137 HD patients receiving regular dialysis. Relevant data were collected, and based on diagnostic criteria, patients were classified into sarcopenia and nonsarcopenia groups. All patients received polysulfone membrane HD at a flow rate of 500 mL/min. Bioelectrical impedance analysis was used to evaluate phase angle (PhA), muscle volume, and body composition.</p><p><strong>Results: </strong>The prevalence of sarcopenia among maintenance HD patients was found to be 40.14%. There was a higher proportion of women (76.36%) with sarcopenia compared to men (<i>P</i> < 0.001). Furthermore, a significant difference was observed in PhA (<i>P</i> < 0.006) between patients undergoing maintenance HD with and without sarcopenia. PhA was positively associated with body mass index, body cell mass, basal metabolic rate, fat-free mass, soft lean mass, and minerals, whereas age and skeletal muscle index showed an inverse significant correlation.</p><p><strong>Conclusion: </strong>Sarcopenia, a condition associated with increased mortality risk, affects a considerable proportion of dialysis patients. It is imperative to urgently identify and develop preventive and therapeutic strategies to counteract the detrimental effects of sarcopenia on the health outcomes of kidney patients.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"29 ","pages":"40"},"PeriodicalIF":1.5,"publicationDate":"2024-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11376717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}