Tao Liu, Ping Zhou, Xin Jiang, Na Wang, Jialing Shou, Yuqiang Fang
{"title":"The complete reversal effect following angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and beta-blockers after the primary diagnosis of dilated cardiomyopathy.","authors":"Tao Liu, Ping Zhou, Xin Jiang, Na Wang, Jialing Shou, Yuqiang Fang","doi":"10.4103/jrms.jrms_626_21","DOIUrl":"10.4103/jrms.jrms_626_21","url":null,"abstract":"<p><strong>Background: </strong>Whether combination administration of angiotensin-converting enzyme inhibitors (ACEIs), angiotensin receptor blockers (ARBs), and beta-blockers (BBs) has a \"reversal\" effect on cardiac structure and function for first-diagnosed idiopathic dilated cardiomyopathy (FSIDCM) patients with unclear etiologies and inducements is unknown.</p><p><strong>Materials and methods: </strong>We studied the effect of the protocol on FSIDCM patients. The effect was investigated in 26 FSIDCM patients. The criteria of \"complete reversal\" included left ventricular end-diastolic diameter (LVEDD) ≤50 mm for females or ≤55 mm for males and left ventricular ejection fraction (LVEF) ≥45%; the criteria of \"partial reversal\" was the decreased rate of LVEDD (ΔLVEDD) >10% or the increase rate of LVEF (ΔLVEF) >10%; the criteria of \"no reversal\" included LVEDD >50 mm for females or >55 mm for males and ΔLVEDD <10%, and LVEF <45% and ΔLVEF <10%.</p><p><strong>Results: </strong>Within the follow-up period, nine patients showed \"complete reversal,\" eight \"partial reversal,\" and nine \"no reversal.\" Improvements in echocardiogram parameters were the most significant in \"complete reversal\" patients (<i>P</i> < 0.001), followed by \"partial reversal\" and \"no reversal\" patients (<i>P</i> < 0.05). The QRS (Q wave, R wave, S wave) duration and symptoms duration in \"complete reversal\" patients were the shortest, followed by \"partial reversal\" and \"no reversal\" patients.</p><p><strong>Conclusion: </strong>ACEIs or ARBs and BBs have a \"complete reversal\" effect on the left ventricular size and function of some FSIDCM patients. Patients with a narrow QRS and short symptom duration may have a good response.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"1 1","pages":"67"},"PeriodicalIF":1.6,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668220/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70821041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation of biofilm formation, virulence factors, and phylogenetic groups among <i>Escherichia coli</i> strains causing urinary tract infection: A global systematic review and meta-analysis.","authors":"Hossein Karballaei Mirzahosseini, Farhad Najmeddin, Atabak Najafi, Arezoo Ahmadi, Hamidreza Sharifnia, Azad Khaledi, Mojtaba Mojtahedzadeh","doi":"10.4103/jrms.jrms_637_22","DOIUrl":"10.4103/jrms.jrms_637_22","url":null,"abstract":"<p><strong>Background: </strong>Different virulence factors are involved in the pathogenesis of urinary tract infection (UTI) caused by Uropathogenic <i>Escherichia coli</i> (UPEC); hence, this study aimed to study the prevalence of biofilm formation, virulence factors, and phylogenetic groups and their correlation with biofilm formation among UPEC isolates through a systematic review and meta-analysis.</p><p><strong>Materials and methods: </strong>A literature search was conducted from 1, 2000, to the end of 2021 in different databases for studies that reported biofilm together with virulence genes or phylogenetic groups in UPEC isolates from patients with UTI according to PRISMA protocol. Data were analyzed by Comprehensive meta-analysis software.</p><p><strong>Results: </strong>The pooled prevalence of biofilm formers was 74.7%. The combined prevalence of phylogenetic Groups A, B1, B2, and D (s) were reported at 19.6%, 11%, 50.7%, and 20.5%, respectively. The most common virulence genes reported worldwide were <i>fimA</i>, <i>ecpA</i>, and <i>fimH</i>, with a combined prevalence of 90.3%, 86.6%, and 64.9%, respectively. The pooled prevalence of biofilm formation in UPEC isolates with phylogenetic Groups A, B1, B2, D, C, and F were 12.4%, 8.7%, 33.7%, 12.4%, 2.6%, and 2.65%, respectively. Several studies showed a correlation between biofilm production and virulence genes, or phylogenetic groups.</p><p><strong>Conclusion: </strong>Regarding data obtained, the high level of combined biofilm formation (74.7%) and the presence of a positive correlation between biofilm production and virulence genes, or phylogenetic groups as reported by the most studies included in the present review, indicates an important role of biofilm in the persistence of UPEC in the UTI.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"1 1","pages":"66"},"PeriodicalIF":1.6,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70821095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The reverse association of dietary antioxidant index with osteoporosis in postmenopausal iranian women: A case-control study.","authors":"Shakiba Solgi, Farid Zayeri, Behnood Abbasi","doi":"10.4103/jrms.jrms_143_22","DOIUrl":"10.4103/jrms.jrms_143_22","url":null,"abstract":"Background: Osteoporosis, a prevalent bone malady, is prevalent in Iran. Several studies have represented the role of dietary antioxidants on osteoporosis. The dietary antioxidant index (DAI) is a valid and reliable index, which indicates a comprehensive view of dietary antioxidant capacity. This study aimed to survey the relationship of the DAI with the risk of osteoporosis in postmenopausal women in Iran. This research aimed to examine the association between the DAI and the risk of osteoporosis among postmenopausal women in Iran. Materials and Methods: In this case–control study, 440 postmenopausal women (220 cases and 220 controls) were enrolled. The dietary intake of contributors was evaluated using a 147-item food frequency questionnaire. To estimate the DAI, the amount of six antioxidant micronutrients such as Vitamins A, C, and E, selenium, manganese, and zinc was standardized. Then, the DAI was estimated by collecting the standardized consumption of these antioxidant micronutrients. Results: Our findings represented the participants in the first (crude odds ratio [OR] = 1.79, 95% confidence interval [CI]: 1.13–2.85, P = 0.013) and second (crude OR = 1.60, 95% CI: 1.01–2.55, P = 0.043) tertiles of the DAI scores had significantly higher odds of osteoporosis compared to those in the third one; while after modifying for confounding factors, this significant reverse relationship was observed just between women in the first and third tertiles of the DAI scores (adjusted OR = 1.90, 95% CI: 1.34–3.18, P = 0.015). Conclusion: The consequence of this study suggested that adherence to a diet rich in antioxidant compounds may have protective effects against osteoporosis.","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"1 1","pages":"64"},"PeriodicalIF":1.6,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70821375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Urinary iodine excretion after using povidone iodine or chlorhexidine gluconate for topical disinfectant in patients undergoing thyroidectomy due to thyroid carcinoma: When to do radio active iodine therapy?","authors":"Soheila Shokrollahi Yancheshmeh, Alireza Firouzfar, Masoud Nazem, Simin Shokrollahi Yancheshmeh, Alireza Pouramini, Marjan Mansourian, Bijan Iraj","doi":"10.4103/jrms.jrms_191_22","DOIUrl":"10.4103/jrms.jrms_191_22","url":null,"abstract":"<p><strong>Background: </strong>Povidone Iodine (PI) is the most frequent antiseptic used as a topical disinfectant in surgery. It has been reported high transcutaneous iodine absorption due to topical PI usage, but there is a lack of data in periods of excess iodine depletion.</p><p><strong>Materials and methods: </strong>This is a cross-sectional study designed to assess serial urinary iodine concentration (UIC) after topical administration of PI to evaluate the transcutaneous iodine absorption and the proper iodine depletion time for safe administration of Radio Active Iodine (RAI) therapy as ablative or adjuvant therapy.</p><p><strong>Results: </strong>Thirty-seven patients with papillary thyroid carcinoma undergoing total thyroidectomy were assigned to the PI group (<i>n</i> = 20) or chlorhexidine gluconate (CHG) group (<i>n</i> = 17). In the PI group, the UIC levels rose to a maximum of 2 times in the 4<sup>th</sup> week after administration and returned to pre-operative levels in the 8<sup>th</sup> week after. In the CHG group, there was a decrease in UIC levels due to a low iodine diet (LID) with a significant P-value of 0.001, <0.001, and 0.001 in the 2<sup>nd</sup>, 4<sup>th</sup>, and 8<sup>th</sup> weeks follow up respectively compared to the PI group. The urinary excretion of excess iodine lasts about 8 weeks after total thyroidectomy until iodine levels turn back to pre-operative values.</p><p><strong>Conclusion: </strong>If the thyroidectomy was prepared with PI, RAI is better to be performed 6-8 weeks after surgery rather than the standard prescription of 4 weeks.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"1 1","pages":"63"},"PeriodicalIF":1.6,"publicationDate":"2023-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70821316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of two ellipsoidal models for the estimation of left ventricular end-systolic stress in patients with significant coronary artery disease.","authors":"Zeinab Alsadat Ahmadi, Manijhe Mokhtari Dizaji, Anita Sadeghpour, Hamideh Khesali, Ata Firouzi","doi":"10.4103/jrms.jrms_4_21","DOIUrl":"10.4103/jrms.jrms_4_21","url":null,"abstract":"<p><strong>Background: </strong>The shape of the left ventricle (LV) is an important index to explore cardiac pathophysiology. A comparison was provided to estimate circumferential, longitudinal, and radial wall stress in LV based on the thick-walled ellipsoidal models of Mirsky and Ghista-Sandler for discriminating significant coronary artery disease (CAD) patients from no CAD patients.</p><p><strong>Materials and methods: </strong>According to the angiography findings, 82 patients with CAD were divided into two groups: 25 patients without significant CAD and 57 patients with significant CAD of single vessel and multivessel. An ellipsoidal LV geometry was used to calculate end-systolic passive stress as the mechanical behavior of LV. Echocardiographic views-based measurements of LV diameters used to estimate the end-systolic wall stress.</p><p><strong>Results: </strong>Circumferential wall stress between the control group and significant CAD groups was significantly elevated for the Ghista model (<i>P</i> = 0.008); also, radial and longitudinal stress of the multi-vessel CAD group was significantly higher than the control group (<i>P</i> = 0.01 and <i>P</i> = 0.005, respectively). All stress parameters of the multi-vessel CAD group were statistically significant compared to the control group for the Mirsky model. Receiver operating characteristics curve analysis was shown the circumferential stress of multi-vessel CAD with an area under the curve (AUC) of 0.736 for the Ghista model and an AUC of 0.742 for the Mirsky model.</p><p><strong>Conclusion: </strong>These results indicated that Ghista and Mirsky model estimates of circumferential passive stress were the potential biomechanical markers to predict patients with multi-vessel CAD. It could be a noninvasive and helpful tool to quantify the contractility of LV.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"1 1","pages":"62"},"PeriodicalIF":1.6,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70820917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The side effect profile of sirolimus and its relationship with some variables: A retrospective study of Iranian renal transplant patients.","authors":"Shahrzad Shahidi, Sahar Vahdat, Abdolamir Atatpour, Shirin Meshkinfar","doi":"10.4103/jrms.jrms_531_22","DOIUrl":"10.4103/jrms.jrms_531_22","url":null,"abstract":"<p><strong>Background: </strong>Sirolimus is a potent immunosuppressive in renal transplantation. However, its use is limited by some reported side effects. The objective of this study was to determine the side effect profile of sirolimus in renal transplant patients.</p><p><strong>Materials and methods: </strong>In the present study, we retrospectively reviewed the medical records of 116 renal transplant patients treated with sirolimus alone or in combination with other immunosuppressive agents at private therapeutic centers in Isfahan, Iran, between March 2009 and February 2020. A checklist was used to collect data on demographic and clinical variables. Data were analyzed with independent samples <i>t</i>-test and Chi-squared test.</p><p><strong>Results: </strong>Our findings indicated that the most prevalent sirolimus-related side effects were edema (42.3%), proteinuria (37.5%), cytopenia (26.9%), abnormal level of liver enzymes (11.7%), and pneumonitis (9.7%). Stratification of side effects by sirolimus dose (<2 mg and ≥2 mg) demonstrated their dose-independent occurrence (<i>P</i> > 0.05). Pneumonitis was the most frequent reason for sirolimus cessation (58.7%). No significant differences were observed between males and females regarding the frequency of reasons for sirolimus cessation (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>Edema, proteinuria, cytopenia, abnormal level of liver enzymes, and pneumonitis were the most prevalent sirolimus-related side effects in renal transplant patients. Further prospective cohort studies are warranted to detect underlying mechanisms and determinants of these side effects in renal transplant patients treated with sirolimus.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"1 1","pages":"58"},"PeriodicalIF":1.6,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70820994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can monkeypox be a sexually transmitted infection?","authors":"Fatemeh Azarkish, Roksana Janghorban","doi":"10.4103/jrms.jrms_439_22","DOIUrl":"10.4103/jrms.jrms_439_22","url":null,"abstract":"","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"1 1","pages":"61"},"PeriodicalIF":1.6,"publicationDate":"2023-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10668216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70820930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehdi Teimouri, Mehdi Motififard, Sahar Sadat Lalehzar, Mohammad Shahsavan, Tala Khayam, Amir Mohammad Taravati, Amirhossein Sadeghian
{"title":"Persistent pain following total knee arthroplasty: The role of underlying diseases.","authors":"Mehdi Teimouri, Mehdi Motififard, Sahar Sadat Lalehzar, Mohammad Shahsavan, Tala Khayam, Amir Mohammad Taravati, Amirhossein Sadeghian","doi":"10.4103/jrms.jrms_190_23","DOIUrl":"10.4103/jrms.jrms_190_23","url":null,"abstract":"<p><strong>Background: </strong>With increasing age and joint-destructive diseases, the need for novel surgeries such as total knee arthroplasty (TKA) has increased. Complications such as pain exacerbation and persistent pain after surgery may occur which increases rehabilitation programs. Factors such as body mass index (BMI), psychiatric disorders, spine diseases, and comorbidities diseases can affect outcomes. Our study was conducted to evaluate the effect of BMI, psychiatric disorders, spine diseases, and underlying diseases on persistent and annoying pain after TKA.</p><p><strong>Materials and methods: </strong>This is a case-control study that was conducted on patients who underwent TKA in Kashani Hospital in Isfahan City in 2020-2022. Demographic data of patients including age and BMI, diabetes mellitus (DM), history of psychiatric disorders, spine disorders such as spondylolisthesis or disc herniation, and other underlying diseases were obtained. Patients were assigned to case or control groups based on pain complaints after surgery. All patients were evaluated 6 months after the initial surgery. After collecting the study data, they were entered into SPSS software (version 25, IBM Corporation, Armonk, NY, USA) and analyzed.</p><p><strong>Results: </strong>We enrolled 35 patients in the case group and 39 patients in the control group between June 2020 and September 2022, based on the severity of pain measured using a Visual Analog Scale score. Our results show that BMI and DM had a meaningful relationship with pain after surgery (<i>P</i> ≤ 0.01). Other factors did not show a significant difference between groups.</p><p><strong>Conclusion: </strong>Underlying diseases, psychiatric diseases, and spine disorders did not significantly affect the pain after TKA. Patients with DM and higher BMI experienced more persistent pain after TKA.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"28 ","pages":"57"},"PeriodicalIF":1.5,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/af/7c/JRMS-28-57.PMC10366980.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9872665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The physical and psychological outcomes of art therapy in pediatric palliative care: A systematic review.","authors":"Elahe Ghayebie Motlagh, Mahmoud Bakhshi, Nayyereh Davoudi, Ali Ghasemi, Hossein Karimi Moonaghi","doi":"10.4103/jrms.jrms_268_22","DOIUrl":"10.4103/jrms.jrms_268_22","url":null,"abstract":"<p><strong>Background: </strong>The integration of art therapy in health care is a growing trend in the care of cancer patients. Therefore, this study aimed to identify the physical and mental benefits of art in children with cancer.</p><p><strong>Materials and methods: </strong>A systematic review of English articles using Google Scholar, MEDLINE via PubMed, Scopus, the Cochrane Database of Systematic Reviews, and the Web of Science was conducted. Relevant keywords for cancer, child, art therapy and their synonyms were used accordingly. All searches were conducted to December 31, 2021.Relevant articles were included studies published in English and involving children aged 0-18 years. Studies evaluated the effects of art therapy in children with cancer.</p><p><strong>Results: </strong>Seventeen studies had inclusion criteria, of which 12 studies were performed by clinical trial and 5 studies were performed by quasi-experimental method. Sixteen studies evaluated one type of art-therapy intervention, while one study used a combination of art-therapy approaches.The results showed that art-based interventions in the physical dimension lead to more physical activity, stability in breathing, and heart rate, and these children reported less pain. In the dimensions of psychology had less anxiety, depression, and anger but at the same time had a better quality of life and more coping-related behaviors.</p><p><strong>Conclusion: </strong>It seems that the use of art therapy in pediatric palliative care with cancer can have good physical and psychological results for the child, but it is suggested to evaluate the effects of these interventions in children at the end of life.</p>","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"28 ","pages":"13"},"PeriodicalIF":1.5,"publicationDate":"2023-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/59/JRMS-28-13.PMC10098136.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9316595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Grace, Masoumeh Sadeghi, K. Turk-Adawi, M. Supervia, M. Fard, Fereydoun Noohi, H. Roohafza, N. Sarrafzadegan
{"title":"Availability and nature of cardiac rehabilitation by province in Iran: A 2018 update of ICCPR's global audit","authors":"S. Grace, Masoumeh Sadeghi, K. Turk-Adawi, M. Supervia, M. Fard, Fereydoun Noohi, H. Roohafza, N. Sarrafzadegan","doi":"10.4103/jrms.jrms_68_21","DOIUrl":"https://doi.org/10.4103/jrms.jrms_68_21","url":null,"abstract":"Background: Cardiac rehabilitation (CR) is scantly available in Iran, although it is the cost-benefit strategy in cardiac patients, It has not been established how CR is delivered within Iran. This study aimed to determine: (a) availability, density and unmet need for CR, and (b) nature of CR services in Iran by province. Materials and Methods: In this cross-sectional sub-study of the global CR audit, program availability was determined through cardiovascular networks. An online survey was then disseminated to these programs in June 2016–2017 which assessed capacity and characteristics; a paper-based survey was disseminated in 2018 to nonresponding and any new programs. CR density and need was computed based on annual incidence of acute myocardial infarction (AMI) in each province. Results: Of the 31 provinces, 12 (38.7%) had CR services. There were 30 programs nationally, all in capital cities; of these, programs in 9 (75.0%) provinces, specifically 22 (73.3%) programs, participated. The national CR density is 1 spot per 7 incident AMI patients/year. Unmet need is greatest in Khuzestan, Tehran and west Azerbaijan, with 44,816 more spots needed/year. Most programs assessed cardiovascular risk factors, and offered comprehensive services, delivered by a multi-disciplinary team, comprised chiefly of nurses, dietitians and cardiologists. Median dose is 14 sessions/program in supervised programs. A third of programs offered home-based services. Conclusion: Where programs do exist in IRAN, they are generally delivered in accordance with guidelines. Therefore, we must increase capacity in CR services in all provinces to improve secondary prevention services.","PeriodicalId":50062,"journal":{"name":"Journal of Research in Medical Sciences","volume":"10 1","pages":""},"PeriodicalIF":1.6,"publicationDate":"2023-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73634756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}