Journal of the American Society of Echocardiography最新文献

{"title":"Speckle-tracking Echocardiography Parameters Associated with Ventricular Arrhythmia Recurrence-free Survival Post-ablation in Structural Heart Disease.","authors":"Siddharth J Trivedi, Richard G Bennett, Karen Byth, Timothy Campbell, Samual Turnbull, Luke Stefani, Saurabh Kumar, Liza Thomas","doi":"10.1016/j.echo.2025.05.004","DOIUrl":"https://doi.org/10.1016/j.echo.2025.05.004","url":null,"abstract":"<p><strong>Background: </strong>Catheter ablation (CA) is indicated for drug-refractory ventricular arrhythmias (VAs). Predicting adverse outcomes (recurrent VA/mortality) post-CA is important; however current tools are imperfect. Speckle tracking echocardiography quantifies global longitudinal strain (GLS), a measure of myocardial deformation, and mechanical dispersion (MD) and delta contraction duration (DCD) (measures of myocardial contraction heterogeneity).</p><p><strong>Objectives: </strong>To examine the association between clinical, procedural, and echocardiographic parameters and subsequent VA recurrence or death.</p><p><strong>Methods: </strong>181 patients (ischemic (n=82), non-ischemic cardiomyopathy (n=99)) with VAs undergoing CA underwent echocardiography including measurements of left ventricular GLS, MD and DCD. Patients were longitudinally followed for first occurrence of VA recurrence or death; in the absence of VA recurrence or death, a patient was deemed to have VA recurrence-free survival.</p><p><strong>Results: </strong>Median follow-up was 21.0 months. After the procedure, twenty patients (11%) died without any prior VA recurrence and 77 patients (43%) experienced VA recurrence of whom 11 subsequently died. Cox proportional hazards regression analysis identified acute procedural failure, ≥2 inducible VAs, DCD, and the interaction between GLS and DCD as significant predictors of VA recurrence-free survival. When GLS and DCD were dichotomised by their median values, (GLS ≤ -11.5% versus > -11.5%; DCD≤190ms versus >190ms), DCD>190ms was a predictor of the composite end-point irrespective of GLS status. MD was not as strong a predictor as DCD.</p><p><strong>Conclusions: </strong>In patients undergoing CA for VAs, the only echocardiographic predictor of VA recurrence-free survival was a prolonged DCD, irrespective of GLS, clinical and procedural factors. Hence, DCD may facilitate risk stratification prior to CA.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144121265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic Features of Right Ventricular Reverse Remodeling in Adults with Repaired Tetralogy of Fallot after Pulmonary Valve Replacement and Impact of Age at Time of Intervention.","authors":"Rebecca L Moore, Jan Leonard, Alexis Z Tomlinson, Stephanie Fuller, Yan Wang, Laura Mercer-Rosa, Yuli Y Kim","doi":"10.1016/j.echo.2025.04.022","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.022","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of Non-invasive Measures of Ventricular Diastolic Stiffness in Single Right Ventricle Patients: A Pilot Study.","authors":"William A Harris, Eric M Graham, Carolyn L Taylor, Andrew Savage, Kimberly E McHugh, Stephanie Gaydos, Arni C Nutting, Andrew M Atz, Donald R Menick, Drew Bickel, Meara Walkley, Shahryar M Chowdhury","doi":"10.1016/j.echo.2025.04.021","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.021","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standardization of Three-Dimensional Tricuspid Valve Annular Size Among Echocardiographic Vendors: The Power of Interchangeable Three-Dimensional Echocardiography.","authors":"Emily Jimenez, Matthew Peters, Tatyanna Somsak, Benjamin Wordell, Priscilla Wessly, Renuka Jain","doi":"10.1016/j.echo.2025.04.019","DOIUrl":"10.1016/j.echo.2025.04.019","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial Right to Left Shunting after Tetralogy of Fallot Repair is Associated with Improved Atrial Function and Shorter Hospital Length of Stay - An Echocardiographic Cohort Study.","authors":"Marc A Delaney, Laura Bennett, Jennifer A Faerber, Andrea L Jones, Anh Duc Mai, Omonigho Ekhomu, Yan Wang, Elizabeth Goldmuntz, Maryam Y Naim, Monique M Gardner, Mark K Friedberg, Laura Mercer-Rosa","doi":"10.1016/j.echo.2025.04.020","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.020","url":null,"abstract":"<p><strong>Background: </strong>Atrial right to left (aRL) shunting is often identified on echocardiograms in the early postoperative period following repair of tetralogy of Fallot (TOF) and thought to reflect poor right ventricular (RV) compliance, but to be possibly beneficial in serving as a \"pop off\" for the RV. We aimed to investigate the relationship between aRL shunting to echocardiographic diastolic function and early postoperative outcomes, hypothesizing that aRL would be associated with worse diastolic function, and with post-operative length of stay (LOS).</p><p><strong>Methods: </strong>Single center cohort study of patients who underwent repair of TOF. Echocardiograms were obtained 2-5 days after repair. Patients were grouped as \"elective\" if repaired after 30 days of age without prior palliation, \"staged\" if they had a neonatal palliation prior to repair, or as \"neonatal\" repair if repaired <30 days age. aRL shunting was compared to all others: bidirectional, left to right, and no atrial shunt detected. Linear regression tested the relationship of aRL with right atrial volumes and right atrial emptying fraction (RAEF), RV inflow/tissue Doppler velocities, and RA peak longitudinal strain and early strain rate. Multivariable negative binomial regression tested the association between aRL with LOS, stratified by repair group.</p><p><strong>Results: </strong>There were 197 TOF patients (60% male, 74% White), most (127, 64%) had elective, 41 (21%) staged, and 29 (15%) neonatal repair. aRL was present in 68 patients (35%). In the overall cohort, aRL shunting was associated with lower RA end diastolic volume, higher RAEF, higher A wave peak velocity, and higher RA peak longitudinal strain. In the subgroup analysis, aRL was associated with higher RAEF and peak longitudinal strain in the elective repair group only, where aRL was also associated with shorter LOS.</p><p><strong>Conclusions: </strong>aRL after TOF repair is associated with better atrial function, and possibly with a combination of robust atrial function in the presence of RV noncompliance, and shorter LOS in patients undergoing elective rTOF, but not in those undergoing a neonatal intervention.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distance Between the Anterior Papillary Muscle and Interventricular Septum Evaluated by Echocardiography to Diagnose Mid-ventricular Obstruction in Hypertrophic Cardiomyopathy.","authors":"Minghu Xiao, Jingjin Wang, Changrong Nie, Changsheng Zhu, Xin Sun, Yanhai Meng, Zhenhui Zhu, Hao Wang, Shuiyun Wang","doi":"10.1016/j.echo.2025.04.018","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.018","url":null,"abstract":"<p><strong>Background: </strong>Left ventricular mid-ventricular obstruction (MVO) is thought to be dynamic with hypertrophic cardiomyopathy (HCM). Therefore, the distance between the anterior papillary muscle and interventricular septum was employed as a parameter named APM-IVS distance for assessing MVO by rest echocardiography.</p><p><strong>Methods: </strong>MVO was defined as a mid-ventricular gradient of ≥ 30 mmHg at rest or after being provoked. APM-IVS distance was analyzed on apical three chamber view at end-diastole.</p><p><strong>Results: </strong>A total of 2125 patients with HCM were enrolled in this study. Among these, data from 1453 patients with measurable APM-IVS distances were analyzed. Of the 1453 patients, 596 had MVO, while 857 did not exhibit MVO. Multivariate logistic regression analyses showed that APM-IVS distance was an independent indicator of MVO (adjusted odds ratio [95% confidence interval (CI)]: 0.487 [0.448-0.529]). The APM-IVS distance demonstrated the highest diagnostic accuracy in identifying MVO, exhibiting an area under the receiver operating characteristic curve of 0.949 (95% CI: 0.937-0.960). The presence of a smaller APM-IVS distance was correlated with increased incidence of left ventricular apical aneurysm and MVO, elevated levels of N-terminal pro brain natriuretic peptide, as well as higher New York Heart Association functional class. Among those with MVO, 198 patients underwent surgical myectomy and were followed up after a median time of 12 months. APM-IVS distance increased from 7.6±2.2 mm to 18.9±4.9 mm, and the peak mid-ventricular gradient decreased from 50 mm Hg (36-57 mmHg) to 3 mmHg (3-7 mmHg) at follow-up.</p><p><strong>Conclusions: </strong>A small APM-IVS distance was associated with MVO, which was alleviated after myectomy following an increase in APM-IVS distance.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144037967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Body Surface Area a Good Anthropometric Scaling Variable for Detecting Differences in Right Atrial and Right Ventricular Structural Parameters in Adults Born Term Versus Preterm?","authors":"Curt G DeGroff","doi":"10.1016/j.echo.2025.04.015","DOIUrl":"10.1016/j.echo.2025.04.015","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144023782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flow State in Aortic Stenosis: \"Whatever the Parameters, as Long as We Identify the Risk\".","authors":"Marie-Annick Clavel, Lionel Tastet","doi":"10.1016/j.echo.2025.04.014","DOIUrl":"10.1016/j.echo.2025.04.014","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echo-Diastology Prediction of Heart Failure Outcomes: Are We Closer to Finding the Rosetta Stone?","authors":"Garred S Greenberg, Mario J Garcia","doi":"10.1016/j.echo.2025.04.013","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.013","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144038419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Elastography With External Vibration for Quantification of Diastolic Myocardial Stiffness","authors":"Tom Meyer MSc ,&nbsp;Brunhilde Wellge ,&nbsp;Gina Barzen MD ,&nbsp;Stefan Klemmer Chandia MSc ,&nbsp;Fabian Knebel MD ,&nbsp;Katrin Hahn MD ,&nbsp;Thomas Elgeti MD ,&nbsp;Thomas Fischer MD ,&nbsp;Jürgen Braun PhD ,&nbsp;Heiko Tzschätzsch PhD ,&nbsp;Ingolf Sack PhD","doi":"10.1016/j.echo.2024.11.009","DOIUrl":"10.1016/j.echo.2024.11.009","url":null,"abstract":"<div><h3>Objectives</h3><div>Heart failure is an increasing global health problem. Approximately 50% of patients with heart failure have heart failure with preserved ejection fraction (HFpEF) and concomitant diastolic dysfunction (DD), in part caused by increased myocardial stiffness not detectable by standard echocardiography. While elastography can map tissue stiffness, cardiac applications are currently limited, especially in patients with a higher body mass index. Therefore, we developed cardiac time-harmonic elastography (THE) to detect abnormal diastolic myocardial stiffness associated with DD.</div></div><div><h3>Material and Methods</h3><div>Cardiac THE was developed using standard medical ultrasound and continuous external vibration for regionally resolved mapping of diastolic shear wave speed as a proxy for myocardial stiffness. The method was prospectively applied to 54 healthy controls (26 women), 10 patients with moderate left ventricular hypertrophy (mLVH; 5 women), and 45 patients with wild-type transthyretin amyloidosis (wTTR; 4 women), 20 of whom were treated with tafamidis. Ten healthy participants were reinvestigated after 2 to 6 months to analyze test-retest reproducibility by intraclass correlation coefficients.</div></div><div><h3>Results</h3><div>Myocardial shear wave speed was measured with good reproducibility (intraclass correlation coefficient = 0.82) and showed higher values in wTTR (3.0 ± 0.7 m/sec) than in mLVH (2.1 ± 0.6 m/sec) and healthy controls (1.8 ± 0.3 m/sec, all <em>P</em> &lt; .05). Area under the curve values were 0.991 and 0.737 for discriminating wTTR and mLVH from healthy controls, respectively. Shear wave speed was reduced in patients after tafamidis treatment (2.6 ± 0.6 m/sec, <em>P</em> = .04), suggesting the potential value of THE for therapy monitoring. Shear wave speed was quantified in the septum, posterior wall, and an automatically masked region (here stated for the septal region).</div></div><div><h3>Conclusions</h3><div>Cardiac THE detects abnormal myocardial stiffness in patients with DD with high penetration depth, independent of body mass index and region selection. Based on standard ultrasound components, cardiac THE is cost-effective and has the potential to become a point-of-care method for stiffness-sensitive echocardiography.</div></div>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 5","pages":"Pages 431-442"},"PeriodicalIF":5.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}