{"title":"Guide for Authors","authors":"","doi":"10.1016/S0894-7317(24)00623-0","DOIUrl":"10.1016/S0894-7317(24)00623-0","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages A11-A20"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143165970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dobutamine in Low-Flow, Low-Gradient Severe Aortic Stenosis With Preserved Ejection Fraction: Is Exercise Testing the Key?","authors":"Eirini Beneki MD, MSc, PhD(c), Kyriakos Dimitriadis MD, PhD, Konstantinos Zisimos MD, PhD, Argyro Kalompatsou MD, MSc, PhD(c), Konstantinos Tsioufis MD, PhD, Constantina Aggeli MD, PhD","doi":"10.1016/j.echo.2024.09.015","DOIUrl":"10.1016/j.echo.2024.09.015","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 54-55"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142564774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hector I. Michelena MD , Joseph J. Maleszewski MD , Jeremy D. Collins MD
{"title":"Mitral Annular Disjunction: An Approximation to the Truth","authors":"Hector I. Michelena MD , Joseph J. Maleszewski MD , Jeremy D. Collins MD","doi":"10.1016/j.echo.2024.11.004","DOIUrl":"10.1016/j.echo.2024.11.004","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 12-15"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mustafa Suppah MD, Hesham Abdalla MD, Kaitlin Roehl PA-C, Juan Farina MD, Reza Arsanjani MD, Jeffrey Geske MD, Steve Ommen MD, Said Alsidawi MD
{"title":"Sustained Benefits of Mavacamten in Patients With Obstructive Hypertrophic Cardiomyopathy: Long-Term Assessment Using Artificial Intelligence–Electrocardiogram and Echocardiographic Data","authors":"Mustafa Suppah MD, Hesham Abdalla MD, Kaitlin Roehl PA-C, Juan Farina MD, Reza Arsanjani MD, Jeffrey Geske MD, Steve Ommen MD, Said Alsidawi MD","doi":"10.1016/j.echo.2024.10.001","DOIUrl":"10.1016/j.echo.2024.10.001","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 47-49"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan R. Lindner MD, FASE, Daniel Forsha MD, FASE, Raymond Stainback MD, FASE
{"title":"The Indispensable and Diverse Role of Clinician-Scientists in Echo Innovation","authors":"Jonathan R. Lindner MD, FASE, Daniel Forsha MD, FASE, Raymond Stainback MD, FASE","doi":"10.1016/j.echo.2024.11.001","DOIUrl":"10.1016/j.echo.2024.11.001","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages A21-A22"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
James N. Kirkpatrick MD, Nova Panebianco MD, MPH, Jose L. Diaz-Gomez MD, MAS, Jimmy C. Lu MD
{"title":"Reply to “Hemodynamic Consultation in the Neonatal Intensive Care Unit: Subspecialty Evolution in Neonatology”","authors":"James N. Kirkpatrick MD, Nova Panebianco MD, MPH, Jose L. Diaz-Gomez MD, MAS, Jimmy C. Lu MD","doi":"10.1016/j.echo.2024.10.006","DOIUrl":"10.1016/j.echo.2024.10.006","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 53-54"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142569585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachael M. Hyland MD, Philip T. Levy MD, Wyman W. Lai MD, Patrick J. McNamara MB, BCh, BAO, MSc, MRCPCH, DCh
{"title":"Targeted Neonatal Echocardiography Based Hemodynamic Consultation in the Neonatal Intensive Care Unit: Subspecialty Evolution in Neonatology","authors":"Rachael M. Hyland MD, Philip T. Levy MD, Wyman W. Lai MD, Patrick J. McNamara MB, BCh, BAO, MSc, MRCPCH, DCh","doi":"10.1016/j.echo.2024.09.014","DOIUrl":"10.1016/j.echo.2024.09.014","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 52-53"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giorgio Fiore MD , Vincenzo Rizza MD , Giacomo Ingallina MD , Francesco Ancona MD , Stefano Stella MD , Federico Biondi MD , Paola Cunsolo MD , Carlo Gaspardone MD , Davide Romagnolo MD , Annamaria Tavernese MD , Martina Belli MD , Davide Margonato MD , Anna Palmisano MD , Antonio Esposito MD , Francesco Maisano MD , Francesco Fulvio Faletra MD , Eustachio Agricola MD
{"title":"Prevalence of Diastolic and Systolic Mitral Annular Disjunction in Patients With Mitral Valve Prolapse","authors":"Giorgio Fiore MD , Vincenzo Rizza MD , Giacomo Ingallina MD , Francesco Ancona MD , Stefano Stella MD , Federico Biondi MD , Paola Cunsolo MD , Carlo Gaspardone MD , Davide Romagnolo MD , Annamaria Tavernese MD , Martina Belli MD , Davide Margonato MD , Anna Palmisano MD , Antonio Esposito MD , Francesco Maisano MD , Francesco Fulvio Faletra MD , Eustachio Agricola MD","doi":"10.1016/j.echo.2024.10.004","DOIUrl":"10.1016/j.echo.2024.10.004","url":null,"abstract":"<div><h3>Backgrounds</h3><div>Mitral annular disjunction (MAD) is commonly evaluated at end systole. However, a systolic-only disjunction is merely apparent, and 2 distinct phenotypes have been identified: True-MAD (atrial displacement of the posterior leaflet in diastole and systole) and Pseudo-MAD (apparent displacement in systole only). The prevalence of True-MAD and Pseudo-MAD in mitral valve prolapse (MVP) is not known. The aim of this study was to assess the prevalence of True-MAD and Pseudo-MAD in myxomatous MVP patients by transthoracic echocardiography (TTE) and to validate TTE compared to cardiac magnetic resonance (CMR; reference standards).</div></div><div><h3>Methods</h3><div>Consecutive patients who underwent TTE for MVP were included. Mitral annular phenotype was evaluated in the TTE parasternal long-axis view. Accuracy (against CMR) and intra-/interrater reliability of TTE were also assessed.</div></div><div><h3>Results</h3><div>Six hundred three consecutive patients were included. The prevalence of True-MAD and Pseudo-MAD was 7% (42) and 37% (221) (<em>P</em> < .05), respectively. Accordingly, 221 of 263 (84%) patients classically classified as “MAD” would have been reclassified as Pseudo-MAD. Pseudo-MAD prevalence and systolic length increased with higher mitral regurgitation (MR) severity (23% for mild MR, 36% for moderate MR, 44% for severe MR [<em>P</em> < .05]; 6 ± 2 mm for mild MR; 8 ± 2 mm for moderate MR; 10 ± 2 mm for severe MR [<em>P</em> < .05]), while True-MAD prevalence was consistent across MR grades. Pseudo-MAD was linked to systolic curling and Pickelhaube. Transthoracic echocardiography showed an overall accuracy of 0.89 (Cohen <em>k</em> 0.80), a substantial interrater agreement of 0.87 (<em>k</em> = 0.76), and an almost perfect intrarater agreement of 0.93 (<em>k</em> = 0.85).</div></div><div><h3>Conclusions</h3><div>True-MAD, unlike Pseudo-MAD, is rare in patients with MVP. Pseudo-MAD is associated with the grade of MR and other echocardiographic features of advanced myxomatous degeneration. Transthoracic echocardiography is an accurate and reliable first-line method to assess mitral annulus morphology in MVP.</div></div>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 1","pages":"Pages 1-11"},"PeriodicalIF":5.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tom Meyer, Brunhilde Wellge, Gina Barzen, Stefan Klemmer Chandia, Fabian Knebel, Katrin Hahn, Thomas Elgeti, Thomas Fischer, Jürgen Braun, Heiko Tzschätzsch, Ingolf Sack
{"title":"Cardiac Elastography With External Vibration for Quantification of Diastolic Myocardial Stiffness.","authors":"Tom Meyer, Brunhilde Wellge, Gina Barzen, Stefan Klemmer Chandia, Fabian Knebel, Katrin Hahn, Thomas Elgeti, Thomas Fischer, Jürgen Braun, Heiko Tzschätzsch, Ingolf Sack","doi":"10.1016/j.echo.2024.11.009","DOIUrl":"10.1016/j.echo.2024.11.009","url":null,"abstract":"<p><strong>Objectives: </strong>Heart failure is an increasing global health problem. Approximately 50% of patients with heart failure have heart failure with preserved ejection fraction (HFpEF) and concomitant diastolic dysfunction (DD), in part caused by increased myocardial stiffness not detectable by standard echocardiography. While elastography can map tissue stiffness, cardiac applications are currently limited, especially in patients with a higher body mass index. Therefore, we developed cardiac time-harmonic elastography (THE) to detect abnormal diastolic myocardial stiffness associated with DD.</p><p><strong>Material and methods: </strong>Cardiac THE was developed using standard medical ultrasound and continuous external vibration for regionally resolved mapping of diastolic shear wave speed as a proxy for myocardial stiffness. The method was prospectively applied to 54 healthy controls (26 women), 10 patients with moderate left ventricular hypertrophy (mLVH; 5 women), and 45 patients with wild-type transthyretin amyloidosis (wTTR; 4 women), 20 of whom were treated with tafamidis. Ten healthy participants were reinvestigated after 2 to 6 months to analyze test-retest reproducibility by intraclass correlation coefficients.</p><p><strong>Results: </strong>Myocardial shear wave speed was measured with good reproducibility (intraclass correlation coefficient = 0.82) and showed higher values in wTTR (3.0 ± 0.7 m/sec) than in mLVH (2.1 ± 0.6 m/sec) and healthy controls (1.8 ± 0.3 m/sec, all P < .05). Area under the curve values were 0.991 and 0.737 for discriminating wTTR and mLVH from healthy controls, respectively. Shear wave speed was reduced in patients after tafamidis treatment (2.6 ± 0.6 m/sec, P = .04), suggesting the potential value of THE for therapy monitoring. Shear wave speed was quantified in the septum, posterior wall, and an automatically masked region (here stated for the septal region).</p><p><strong>Conclusions: </strong>Cardiac THE detects abnormal myocardial stiffness in patients with DD with high penetration depth, independent of body mass index and region selection. Based on standard ultrasound components, cardiac THE is cost-effective and has the potential to become a point-of-care method for stiffness-sensitive echocardiography.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Information for Readers","authors":"","doi":"10.1016/S0894-7317(24)00534-0","DOIUrl":"10.1016/S0894-7317(24)00534-0","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"37 12","pages":"Pages A11-A12"},"PeriodicalIF":5.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143154646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}