Journal of the American Society of Echocardiography最新文献

{"title":"Life Beyond ISCHEMIA in Stress Echocardiography","authors":"Eugenio Picano MD, PhD","doi":"10.1016/j.echo.2025.03.013","DOIUrl":"10.1016/j.echo.2025.03.013","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":"38 6","pages":"Pages 482-485"},"PeriodicalIF":5.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obstruction in Hypertrophic Cardiomyopathy: Don't Forget Midventricular Obstruction.","authors":"Kendra M Gilreath, Jeffrey B Geske","doi":"10.1016/j.echo.2025.05.014","DOIUrl":"https://doi.org/10.1016/j.echo.2025.05.014","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Deep learning to Predict Cardiovascular Magnetic Resonance Findings from Echocardiography Videos.","authors":"Yuki Sahashi, Milos Vukadinovic, Grant Duffy, Debiao Li, Susan Cheng, Daniel S Berman, David Ouyang, Alan C Kwan","doi":"10.1016/j.echo.2025.05.016","DOIUrl":"10.1016/j.echo.2025.05.016","url":null,"abstract":"<p><strong>Background: </strong>Echocardiography is the most common modality for assessing cardiac structure and function. While cardiac magnetic resonance (CMR) imaging is less accessible, CMR can provide unique tissue characterization including late gadolinium enhancement (LGE), T1 and T2 mapping, and extracellular volume (ECV) which are associated with tissue fibrosis, infiltration, and inflammation. Deep learning has been shown to uncover findings not recognized by clinicians, however it is unknown whether CMR-based tissue characteristics can be derived from echocardiography videos using deep learning.</p><p><strong>Objective: </strong>To assess the performance of a deep learning model applied to echocardiography to detect CMR-specific parameters including LGE presence, and abnormal T1, T2 or ECV.</p><p><strong>Methods: </strong>In a retrospective single-center study, adult patients with CMRs and echocardiography studies within 30 days were included. A video-based convolutional neural network was trained on echocardiography videos to predict CMR-derived labels including LGE presence, and abnormal T1, T2 or ECV across echocardiography views. The model was also trained to predict presence/absence of wall motion abnormality (WMA) as a positive control for model function. The model performance was evaluated in a held-out test dataset not used for training.</p><p><strong>Results: </strong>The study population included 1,453 adult patients (mean age 56±18 years, 42% female) with 2,556 paired echocardiography studies occurring at a median of 2 days after CMR (interquartile range 2 days prior to 6 days after). The model had high predictive capability for presence of WMA (AUC 0.873 [95%CI 0.816-0.922]) which was used for positive control. However, the model was unable to reliably detect the presence of LGE (AUC 0.699 [0.613-0.780]), abnormal native T1 (AUC 0.614 [0.500-0.715]), T2 0.553 [0.420-0.692], or ECV 0.564 [0.455-0.691]).</p><p><strong>Conclusions: </strong>Deep learning applied to echocardiography accurately identified CMR-based WMA, but was unable to predict tissue characteristics, suggesting that signal for these tissue characteristics may not be present within ultrasound videos, and that the use of CMR for tissue characterization remains essential within cardiology.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the J-wave as a Marker of Diastolic Dysfunction in Heart Failure with Preserved Ejection Fraction.","authors":"Tooba Alwani, Ashley P Akerman, Nora Al-Roub, Constance Angell-James, Madeline A Cassidy, Rasheed Thompson, Lorenzo Bosque, Katharine Rainer, William Hawkes, Hania Piotrowska, Paul Leeson, Gary Woodward, Patricia A Pellikka, Ross Upton, Jordan B Strom","doi":"10.1016/j.echo.2025.05.015","DOIUrl":"https://doi.org/10.1016/j.echo.2025.05.015","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Not There Yet: Rethinking the Path for Echocardiography Tissue Characterization with Artificial Intelligence.","authors":"Christina Luong, Wendy Tsang","doi":"10.1016/j.echo.2025.05.011","DOIUrl":"https://doi.org/10.1016/j.echo.2025.05.011","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic Evaluation of Carcinoid Heart Disease.","authors":"Chadi Ayoub, Isabel G Scalia, S Allen Luis, Juan A Crestanello, William J Mauermann, Thorvardur R Halfdanarson, Heidi Connolly, Patricia A Pellikka","doi":"10.1016/j.echo.2025.05.013","DOIUrl":"https://doi.org/10.1016/j.echo.2025.05.013","url":null,"abstract":"<p><p>Carcinoid heart disease (CaHD) is a complication that occurs in patients with metastatic neuroendocrine tumors (usually to the liver) and carcinoid syndrome. Hormonal release causes endocardial thickening, typically affecting right-sided cardiac valves. Symptomatic patients with CaHD have a poor prognosis, and management of valvular heart disease is complicated by metastasis and other associated conditions and carries a higher risk than management of other acquired valve disease. Clinical and biomarker assessment are used for screening and echocardiography is the diagnostic imaging backbone used for identification of CaHD, as well as grading of severity of valvular lesions and associated chamber dysfunction. Echocardiography is critical in the evaluation for surgical intervention, as well as in guiding surgery and postoperative surveillance. This article reviews in detail applications of echocardiography in patients with CaHD.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feeding the Diagnostic Beast that is Diastolic Dysfunction: Are LA Coupling and Stiffness Indices Core Nutrients or Impractical Supplements?","authors":"Bradley S Lander, Brian D Hoit","doi":"10.1016/j.echo.2025.05.009","DOIUrl":"https://doi.org/10.1016/j.echo.2025.05.009","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144183093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-Invasive Pressure-Volume Analysis by Three-Dimensional Echocardiography: A Novel Powerful Method for Evaluating Left Ventricular Function.","authors":"Lars-Egil R Hammersboen, Espen Boe, Jürgen Duchenne, John M Aalen, Hans Henrik Odland, Manuel Villegas-Martinez, Vetle C Frostelid, Faraz H Khan, Ole Jakob Sletten, Marit Witsoe, Helge Skulstad, Filip Rega, Olivier Gheysens, Jens-Uwe Voigt, Otto A Smiseth, Marie Stugaard, Espen W Remme","doi":"10.1016/j.echo.2025.05.008","DOIUrl":"https://doi.org/10.1016/j.echo.2025.05.008","url":null,"abstract":"<p><strong>Background: </strong>Pressure-volume (PV) analysis is the gold standard for evaluating left ventricular (LV) function but is rarely used clinically due to its invasiveness. We validated a non-invasive method for PV analysis by 3D echocardiography against invasive reference measurements and a novel index of LV efficiency against LV efficiency derived from metabolism by positron emission tomography-computed tomography (PET/CT).</p><p><strong>Methods: </strong>In 22 canines, LV volume was measured invasively using piezoelectric crystals and LV pressure by micromanometer. Echocardiography and peak pressure were used to obtain 3D LV volume traces and LV pressure trace estimates. Stroke work, single-beat contractility indices, arterial elastance and an index of LV efficiency were derived from echocardiography and compared with their invasively measured counterparts at baseline and different interventions. In 12 sheep, the LV efficiency index was compared with efficiency calculated as stroke work divided by total LV glucose metabolism from PET/CT. The sheep underwent 8 weeks of rapid dyssynchronous pacing to induce heart failure (HF). Recordings were performed during synchronous and dyssynchronous electrical activation, at baseline, and after 8 weeks pacing-induced HF.</p><p><strong>Results: </strong>In canines, there was a very good correlation and agreement between non-invasive and invasive measurements of LV stroke work (r=0.98, P<0.0001; difference 237±212 mmHg×ml, mean±SD). The non-invasive and invasive efficiency indices also showed very good agreement (r=0.95, P<0.0001; difference 0.4±3.4%). The changes in LV function by the different interventions resulted in similar changes in the non-invasive and invasive PV indices (both P<0.005). In sheep, the efficiency index showed similar decline compared to efficiency by PET/CT after induction of HF and after switching from synchronous to dyssynchronous electrical activation (r=0.67, P<0.001 for all interventions).</p><p><strong>Conclusions: </strong>Non-invasive PV analysis by 3D echocardiography is feasible and accurate, making PV-loop parameters for evaluating LV function accessible for clinical use. Further studies should explore the clinical utility of this method.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safe Sedation in the Echo Lab Using Intranasal Dexmedetomidine Does Not Require Fasting.","authors":"Meaghan Boeker, Deborah Walbergh, Sara Shreve, Sravya Bagli, Peter Frommelt, David Saudek","doi":"10.1016/j.echo.2025.04.017","DOIUrl":"https://doi.org/10.1016/j.echo.2025.04.017","url":null,"abstract":"","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144133309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Semi-invasive Pressure-flow Plots Obtained Using Exercise Echocardiography Relate to Clinical Status and Exercise Capacity in Patients with a Fontan Circulation.","authors":"Aleksandra Cieplucha, Hannah Van Belle, William R Miranda, Youri Bekhuis, Elise Decorte, Mathijs Michielsen, Pieter De Meester, Els Troost, Irene Cattapan, Thomas Rosseel, Jan Verwerft, Guido Claessen, Véronique A Cornelissen, Kaatje Goetschalckx, Marc Gewillig, Werner Budts, Alexander Van De Bruaene","doi":"10.1016/j.echo.2025.05.007","DOIUrl":"https://doi.org/10.1016/j.echo.2025.05.007","url":null,"abstract":"<p><strong>Aims: </strong>Exercise echocardiography with peripheral venous pressure measurement (CPETecho-PVP) may provide superior insights into the pathophysiology of Fontan failure compared to standard cardiopulmonary exercise testing. Accordingly, we assessed (1) the clinical and hemodynamic correlates of pressure-flow plots obtained from CPETecho-PVP in Fontan patients and (2) the relationship between pressure-flow plots and exercise capacity.</p><p><strong>Methods: </strong>Forty-one consecutive Fontan patients underwent CPETecho-PVP. PVP was measured in the distal upper extremity using an 18-20-gauge intravenous line. A multipoint PVP/cardiac output (CO) slope was calculated as a linear approximation using linear regression analysis from individual pressure-flow plots. A PVP/CO >3 mmHg/L/min was considered elevated.</p><p><strong>Results: </strong>Median age was 28 (range 17-60) years; LV dominance was present in 32 (78%) patients. Compared to patients with a PVP/CO slope ≤3 mmHg/L/min (n=29), those with a PVP/CO slope >3 mmHg/L/min were more likely to have a NYHA functional class III-IV (p=0.005), lung pathology (p=0.004), a history of atrial arrhythmia (p=0.009) or thrombo-embolism (p=0.02). Additionally, a PVP/CO slope >3 mmHg/L/min was associated with higher NT pro-BNP levels (325.0 [176.3-590.0] vs. 150.5 [61.3 - 255.0] ng/L, p=0.034), lower peak oxygen consumption (peak VO₂) 48.7±13.3 vs 65.2±15.3 % predicted, p=0.003), heart rate reserve (65 [42-105] vs. 100 [75-127] % predicted, p=0.010) and peak cardiac index (CI) (3.8±0.8 vs 6.3±1.5 L/min.m², p<0.001). Rest-to-peak change in HR (p<0.001) and CI (p=0.006), %predicted forced vital capacity (p=0.044) and PVP/CO slope (p=0.009) were all related to % predicted peak VO₂.</p><p><strong>Conclusions: </strong>A steeper PVP/CO plot is associated with worse clinical status, including lower exercise capacity. This supports the notion of implementing the CPETecho-PVP in the standard of care for Fontan patients.</p>","PeriodicalId":50011,"journal":{"name":"Journal of the American Society of Echocardiography","volume":" ","pages":""},"PeriodicalIF":5.4,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144133314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}