Journal of Voice最新文献

{"title":"The Development of Voice Quality in Second Language Speech Acquisition: A Case Study of the Parallel Speech Corpus of Chinese Natives and Arabic Natives.","authors":"Jia Guo, Wei Huang, Muhannad Alkhattabi, Jiachun Liu, Qibin Ran","doi":"10.1016/j.jvoice.2025.02.028","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.028","url":null,"abstract":"<p><strong>Objectives: </strong>The primary objective of this study is to investigate whether the voice quality in second language (L2) speech production changes over time as learners progress in their L2 acquisition.</p><p><strong>Methods: </strong>A total of 83 Arabic native speakers learning Chinese (59 males and 24 females) and 62 Chinese native speakers learning Arabic (23 males and 39 females) participated in the study. The participants had varying durations of L2 learning (DOL) experience. Each participant recorded word lists in both their first language (L1) and L2, and these recordings were analyzed for voice quality. The acoustic parameters examined included jitter, shimmer, F₀ mean, and F₀ range. A method for calculating the differences in voice quality between L2 and L1 was employed to dissipate voice difference. A linear mixed-effects model was fitted in R to analyze the effects of DOL, gender, and native language background on the L2-L1 voice quality differences.</p><p><strong>Results: </strong>A significant triple interaction effect of DOL, gender, and native language background was observed for jitter, shimmer, and F₀ mean. These findings indicate that the effect of DOL on voice quality in L2 speech production is influenced by both gender and language background. The general trend showed that, with increasing learning duration, participants exhibited greater jitter and shimmer, while F₀ mean and F₀ range progressively approached the target language.</p><p><strong>Conclusions: </strong>The findings demonstrate that voice quality in L2 speech production changes over time with learning duration. These changes are influenced by gender, and since the language-specific nature of voice quality in L2 production, the impact of learning duration on voice quality is also influenced by the learners' native language background.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Rosuvastatin and Calcitriol on Preventing Voice Change After Thyroidectomy: A Randomized Controlled Trial.","authors":"Mehdi Ghasemian, Mehrdad Karajizadeh, Mohammad Reza Yousefi, Mahnaz Yadollahi, Shahram Paydar","doi":"10.1016/j.jvoice.2025.02.033","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.033","url":null,"abstract":"<p><strong>Hypothesis: </strong>Thyroidectomy is a procedure for treatment of thyroid lesions. A common adverse effect is voice change that impairs the patient's well-being. This study aimed to investigate the effect of Rosuvastatin and Calcitriol on preventing voice change after thyroidectomy.</p><p><strong>Study design: </strong>This is a parallel, single-blinded, block-randomized controlled trial in a tertiary medical center in southern Iran, Shiraz.</p><p><strong>Methods: </strong>Adult patients scheduled for total thyroidectomy in 2023 were randomly assigned to one of three groups: Rosuvastatin, Rosuvastatin and Calcitriol, or no anti-inflammatory medication starting 14 days before surgery. The surgeon and the individuals who collected the data were blinded to the allocated groups. Voice change was evaluated 2 weeks after surgery. Written consent was obtained.</p><p><strong>Results: </strong>In total, 177 patients were included in this study, 29 (16.4%) males and 148 (83.6%) females. In total, 66 (37.3%) received Rosuvastatin and Calcitriol, 54 (30.5%) received only Rosuvastatin, and 57 (32.2%) did not receive any medication 2 weeks prior to surgery. Consequently, 123 (69.5%), 42 (23.7%), and 12 (6.8%) had minimal, moderate, and severe voice disorder. Voice change was not significantly different among patients who received Rosuvastatin and Calcitriol and Rosuvastatin alone compared with the group with no drugs (P value = 0.199 and 0.646, respectively).</p><p><strong>Conclusion: </strong>This study suggests that there was no difference in the severity of voice change or in the components of the Voice Handicap Index between patients who received medication and those who did not. Further investigations are warranted to optimize patients' outcomes and quality of life after thyroidectomy.</p><p><strong>Trial registration number: </strong>IRCT20230711058741N1.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dysbiosis Patterns in Glottic and Laryngeal Cancers: A Systematic Review of Microbiome Alterations.","authors":"Jérôme R Lechien","doi":"10.1016/j.jvoice.2025.02.036","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.036","url":null,"abstract":"<p><strong>Background: </strong>This systematic review summarized current evidence regarding the role of upper aerodigestive tract microbiomes (UAM) in laryngeal squamous cell carcinoma (LSCC) development, progression, clinical, and oncological outcomes.</p><p><strong>Methods: </strong>Two investigators systematically search PubMed, Scopus, and Cochrane Library databases for studies investigating microbiome characteristics, mechanistic roles, and associations with clinical and oncological outcomes in LSCC according to the Preferred Reporting Items For A Systematic Review And Meta-analysis statements. The bias analysis was conducted with the methodological index for nonrandomized studies.</p><p><strong>Results: </strong>Ten studies were included, accounting for 491 LSCC patients. LSCC tissues demonstrated lower bacterial diversity compared with controls. Taxonomic analyses suggested an overrepresentation of Bacteroidetes (Prevotella) and Fusobacteriota (Fusobacterium) in LSCC, while Firmicutes (Stomatobaculum longum, Abiotrophia, Gemella, and Streptococcus) and Actinobacteria (Actinomyces, Corynebacterium, and Rothia mucilaginosa) were predominant in control tissues. Firmicutes demonstrated the largest compositional variation across studies, with 30.9%-63.6% abundance in LSCC compared with 13.9%-32% in controls. Two studies explored microbiome signatures: one for LSCC diagnosis and another for prognosis. Substantial methodological heterogeneity was observed across studies regarding confounding factor analysis, UAM assessment protocols, and control tissue selection.</p><p><strong>Conclusion: </strong>The current literature supports potential distinct UAM signatures between LSCC and noncancerous tissues, with Bacteroidetes and Fusobacteriota enriched in LSCC tissues. Although emerging evidence supporting the key role of UAM in the development of LSCC, substantial methodological heterogeneity across studies necessitates standardized protocols for future investigations.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating How Age Affects Self-Perception and Voice Awareness in Parkinson's Disease.","authors":"Francisco Contreras-Ruston, Héctor Arriagada-Concha, Antonia Lagos-Villaseca, Sandra Rojas, Carla Napolitano, Sonja A Kotz, Jordi Navarra","doi":"10.1016/j.jvoice.2025.02.032","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.032","url":null,"abstract":"<p><strong>Objective: </strong>Parkinson's disease (PD) presents with voice disturbances accompanied by sensory processing and awareness deficits. Sensory feedback from the voice, which is essential in speech production, is often impaired in individuals with PD (IwPD), potentially leading to such difficulties in the self-perception and awareness of voice disorder. However, aging naturally affects sensory and motor brain systems, including those involved in voice production; therefore, it remains unclear whether the combined effects of age and PD exacerbate deficits in voice self-perception and awareness deficit. This study explored how age and sensory feedback in IwPD interact and affect self-perception and awareness of voice changes. Patient-reported outcome measures (PROMs) specific to the voice may not be efficient enough to capture voice changes in IwPD.</p><p><strong>Methods: </strong>The study included three groups of similar ages: 27 IwPD (61-79 years), 25 individuals with general voice disorders (GVD, aged 57-83 years), and 28 healthy controls (HC, aged 60-80 years). Self-perception of the voice was assessed by three PROMs: the Voice Symptoms Scale, Voice Handicap Index-10, and Voice-Related Quality of Life. Voice loudness was recorded and analyzed using univariate comparisons between the PROM scores. Further, multivariate techniques, such as principal component analysis (PCA) and cluster analysis, were used to identify intergroup differences in voice quality and voice self-awareness.</p><p><strong>Results: </strong>The IwPD group showed lower self-perception and awareness of voice problems than the GVD and HC groups. Within the IwPD group, age did not show a significant impact on self-perception of voice and awareness. This group showed slightly higher PROM scores than the HCs. In contrast, the GVD group showed marked differences in all PROMs and voice parameters compared with the HC and PD groups. PCA revealed significant differences in total scores and voice loudness between the groups.</p><p><strong>Conclusions: </strong>These findings suggest that age-related changes in sensory feedback are not significant factors affecting reduced self-perception and awareness of voice changes in IwPD. PCA and cluster analysis revealed distinct patterns among the groups, with GVD forming a separate cluster and IwPD displaying variability, partially overlapping with HC and GVD. This variability underscores the limited diagnostic utility of PROMs used to identify voice problems in IwPD compared with older individuals without PD, who generally exhibit greater awareness of voice disorders. Future studies should focus on developing tailored PROMs to better capture these challenges in IwPD.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Medialization Procedures on Laryngopharyngeal Reflux in Patients With Glottic Insufficiency: A Preliminary Study.","authors":"Sriprachodaya Gaddam, Trevor DeSilva, Zachary Funk, Adam Gardi, Katherine Mullen, Hye Rhee Chi, Mary J Hawkshaw, Omar Ramadan, Robert T Sataloff","doi":"10.1016/j.jvoice.2025.02.035","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.035","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate whether medialization procedures performed for management of glottic insufficiency also reduce patients' concurrent laryngopharyngeal reflux (LPR) signs.</p><p><strong>Study design: </strong>Retrospective chart review.</p><p><strong>Methods: </strong>A retrospective chart review was conducted of patients who visited the office of the senior author, received a diagnosis of glottic insufficiency and LPR, and were offered medialization procedures. Patients were categorized into two groups: those who received medialization surgery (n = 39) and those who did not (n = 40). Reflux finding scores (RFS) collected pretreatment and post treatment were compared between groups. 24-hour pH-impedance results also were evaluated pretreatment and post treatment when available.</p><p><strong>Results: </strong>No significant changes were found in RFS between preintervention and postintervention within either the medialization group or the non-medialization group. Between-group comparisons showed no significant differences in RFS pre-and postintervention for each of the subcategories. Patients in the medialization group showed improvement in 24-hour pH-impedance testing with decreased total reflux events (mean reflux events pre = 59; mean reflux events post = 39) as well as total upright reflux events (mean reflux events pre = 47; mean reflux events post = 16) at the proximal sensor. However, these improvements were not statistically significant (P = 0.12, P = 0.17, respectively).</p><p><strong>Conclusion: </strong>Medialization procedures in patients with glottic insufficiency may not improve the laryngeal effects of LPR. Further research with more subjects is encouraged to determine whether treating glottic insufficiency may also improve LPR symptoms.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maximum Phonation Time: Relationship Between Different Measurement Methods, Sex, and Body Mass Index.","authors":"Maria Fernanda de Queiroz Prado Bittencourt, Marta Assumpção de Andrada E Silva","doi":"10.1016/j.jvoice.2024.10.008","DOIUrl":"https://doi.org/10.1016/j.jvoice.2024.10.008","url":null,"abstract":"<p><strong>Objective: </strong>To associate different methods of measuring maximum phonation time (MPT) according to sex and body mass index (BMI).</p><p><strong>Methods: </strong>The study included 30 men and 30 women aged between 18 and 45years. Four different methods of measuring MPT were tested, and the obtained values were compared between sexes and BMI.</p><p><strong>Results: </strong>There was no statistically significant difference between the different methods of measuring MPT. Comparisons between sexes showed significant differences between men and women. Regarding BMI, overweight subjects had higher MPT values than eutrophic subjects.</p><p><strong>Conclusion: </strong>No differences were found between the possible methods of measuring MPT. Men had higher MPT values than women, and overweight subjects also obtained higher MPT values.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomized Controlled Trial Comparing the Effect of Anti-Fog Agents on Flexible Nasendoscopy View.","authors":"Holly Hendron, Stephanie Germain, Prodip Das, Philippe Bowles","doi":"10.1016/j.jvoice.2025.02.012","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.012","url":null,"abstract":"<p><strong>Objectives: </strong>Flexible nasendoscopy (FNE) is an essential part of otolaryngological examination, and accurate visualization of the upper aerodigestive tract is crucial in order to detect pathological findings and guide further management. Fogging of the endoscopic lens poses a threat to picture quality. Studies comparing the efficacy of anti-fog agents for FNE are lacking. The aim of this study was to assess whether the choice of commercial versus natural anti-fog agents versus no anti-fog agents had an impact on picture quality obtained from FNE.</p><p><strong>Methods: </strong>178 patients undergoing assessment for laryngeal pathology were randomly allocated to one of three groups to receive commercial anti-fog spray, natural anti-fog (patient's own saliva), or no anti-fog agent prior to FNE examination. Video recordings of the larynx from each participant were collected, which were independently assessed by two consultant otolaryngologists blinded to the patient groups, with visual analogue scale (VAS) scores assigned as outcome measures, ranging from 0 to 10. The VAS scores were analyzed with one-way ANOVA.</p><p><strong>Results: </strong>No significant difference in mean VAS scores was observed by either consultant otolaryngologist in picture quality when comparing anti-fog spray, saliva and no agent (ANOVA, P = 0.09 for Consultant A and P = 0.06 for Consultant B). There was inter-rater reliability between Consultant A and B with percentage agreement of 75%.</p><p><strong>Conclusions: </strong>The choice between commercial anti-fog spray, saliva and no anti-fog agent does not affect view obtained from FNE. This study's findings have the potential to inform FNE guidelines, thereby minimizing the economical and environmental impacts of unnecessary additional equipment.</p><p><strong>Level of evidence: </strong>Level II evidence.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Insights Into the Role of Personality in Adherence to Voice Rest After Phonomicrosurgery.","authors":"Marianna Rubino, Ruiqing Stephanie Fan, Yin Yiu, Nelson Roy, Abigail Dueppen, Teresa Procter, Maurice E Goodwin, Apurva A Thekdi, Stephanie K Daniels, Ashwini Joshi","doi":"10.1016/j.jvoice.2025.01.031","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.01.031","url":null,"abstract":"<p><strong>Objectives/hypothesis: </strong>The purpose of this preliminary investigation was to explore the relationship between personality and adherence to voice rest in individuals following phonosurgery for benign mucosal or submucosal/lamina propria lesions. We hypothesized that adherence to voice rest would be inversely related to Extraversion and directly related to Conscientiousness, two superfactor traits of the Big Five personality model.</p><p><strong>Study design: </strong>This was a prospective, longitudinal, cohort study.</p><p><strong>Methods: </strong>Twenty-five patients (eight men, 17 women; mean age = 46.25 years; SD = 14.38) of Houston Methodist Hospital's Department of Otolaryngology, Head and Neck Surgery underwent microflap phonosurgery. Each participant provided demographic information, completed the Ten Item Personality Inventory (a brief Big Five personality instrument), and wore a vocal dosimeter to objectively measure voice rest adherence during a seven-day, postoperative period.</p><p><strong>Results: </strong>The participants' mean personality scores were higher than reported norms across all Big Five traits. Contrary to our hypotheses, (1) Extraversion related directly to voice rest adherence, and (2) no other personality traits (including Conscientiousness) related to voice rest adherence.</p><p><strong>Conclusions: </strong>Although extraverts have been described as talkative, assertive, and outgoing, we found that high Extraversion was related to less vocalizing during the voice rest period. Our results are compatible with the health psychology literature that describes a positive relation between Extraversion and adherence to preventive healthcare practices. Future research should employ a larger, single-sex sample, potentially with greater similarity between patient diagnoses. Clinically, such data could inform counseling approaches to facilitate voice rest adherence and potentially improve surgical outcomes.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Group Speech-Language Pathology Therapy for Teachers With Voice Disorders.","authors":"Mariane Maião Pereira, Léslie Piccolotto Ferreira, Emilse Aparecida Merlin Servilha, Maria Cristina de Menezes Borrego, Marta Assumpção de Andrada E Silva, Susana Pimentel Pinto Giannini","doi":"10.1016/j.jvoice.2025.02.019","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.019","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the effects of implementing a Voice Program in a group setting, focusing on the record of vocal symptoms and self-reporting by teachers with voice disorders.</p><p><strong>Method: </strong>This is a longitudinal study with preintervention and postintervention assessments. The study included 23 female teachers with voice disorders who participated in the Voice Program at a municipal hospital. All participants underwent otorhinolaryngological assessment (diagnosis) and speech-language evaluation of voice (assessment of health aspects and treatments, GRBAS Scale (classifies hoarseness, roughness, breathiness, asthenia [weakness] and tension), pitch, loudness, resonance, respiratory type, and pneumophonoarticulatory coordination) and completed the Voice Handicap Index (VHI-10) and Vocal Production Condition-Teacher instruments. The Screening Index for Voice Disorder (SIVD), Vocal Fatigue Index (VFI), and Voice Self-Report (VSR-Initial and VSR-Final) instruments were used for group comparison of preintervention and postintervention data collection. Effects were recorded by analyzing these instruments and participant self-reports. Statistical analysis compared SIVD and VFI scores before and after the intervention. The VSR-I and VSR-F analysis was conducted by reviewing the material to establish objective categories for record classification.</p><p><strong>Results: </strong>Preintervention and postintervention data analysis showed a statistically significant reduction in SIVD scores postintervention and a decrease in the total symptoms reported (notably for clearing throat, dry cough, cough with secretion, and pain while swallowing), as well as in the overall average of VFI domains. Upon completing the program, self-reports showed that teachers noted changes in their voices, reporting aspects related to their vocal care and habits.</p><p><strong>Conclusion: </strong>The analyzed program proved effective in reducing vocal symptoms, especially those related to vocal fatigue, accompanied by positive self-reports on habit changes.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vocal Function Changes in Patients With Benign Thyroid Nodules After Radiofrequency Ablation.","authors":"Cheng-Hsun Hsieh, Yu-Fen Lin, Yu-Chi Huang, Po-Cheng Chen, Hsin-Yen Tsai, Wei-Che Lin","doi":"10.1016/j.jvoice.2025.02.024","DOIUrl":"https://doi.org/10.1016/j.jvoice.2025.02.024","url":null,"abstract":"<p><strong>Objective: </strong>To objectively evaluate changes in vocal function in patients with benign thyroid nodules following radiofrequency ablation (RFA).</p><p><strong>Methods: </strong>Seventy-five patients diagnosed with benign thyroid nodules who underwent RFA were included in the study. These patients received thyroid sonography both preRFA and 3 months postRFA. Additionally, vocal function assessments, including aerodynamic and acoustic evaluations, were performed at specific time points: preRFA, immediately postRFA, and 3 months postRFA.</p><p><strong>Results: </strong>The results indicated a significant decrease in maximum phonation time (MPT) immediately postRFA (MPT = 11.25; P < 0.001) and 3 months postRFA (MPT = 12.40; P = 0.007) compared with preRFA (MPT = 13.88), suggesting potential dysphonia. Additionally, compared with preRFA (jitter = 0.86; shimmer = 0.35), transient increases in jitter (jitter = 1.19; P = 0.013) and shimmer (shimmer = 0.37; P = 0.039) were observed immediately postRFA, returning to baseline at 3 months, indicating vocal recovery of the vibratory characteristics. No significant correlations were found between preRFA nodule volume (correlation coefficient = 0.002; P = 0.991) or volume reduction ratio (VRR; correlation coefficient = -0.129; P = 0.415) and MPT changes.</p><p><strong>Conclusions: </strong>In patients with benign thyroid nodules, RFA affects both acoustic and aerodynamic vocal function. Regardless of initial nodule volume or high VRR at 3 months postablation, a significant decrease in MPT was observed. This study underscores the importance of objective vocal assessment for monitoring and guiding interventions for vocal recovery postRFA.</p><p><strong>Data availability: </strong>The datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.</p>","PeriodicalId":49954,"journal":{"name":"Journal of Voice","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}