Sao Paulo Medical Journal最新文献

{"title":"Effects of probiotics on gastrointestinal symptoms, anthropometric measurements, and breastfeeding duration in infants with colic: a randomized control trial.","authors":"Aysu Yıldız Karaahmet, Gülümser Dolgun, Metehan Özen","doi":"10.1590/1516-3180.2023.0069.R1.31052023","DOIUrl":"10.1590/1516-3180.2023.0069.R1.31052023","url":null,"abstract":"<p><strong>Background: </strong>Infantile colic has a multifactorial etiology. Recent studies have suggested that probiotics may be effective in its management.</p><p><strong>Objective: </strong>This study was carried out to evaluate the effect of the Actiregularis strain (5×106 cfuml) included in maternal nutrition on gastrointestinal problems, growth development, and breastfeeding outcomes in infantile colic.</p><p><strong>Design and setting: </strong>The study was a randomized controlled trial conducted in the neonatal outpatient clinic of a training and research hospital in Turkey.</p><p><strong>Methods: </strong>A probiotic drink containing the Actiregularis (5×106 cfuml) strain was added to the diet of mothers in the probiotics group once daily for 15 consecutive days. Data were collected for each infant's 0th (birth), 1st, 4th, and 6th months.</p><p><strong>Results: </strong>Infants whose mothers were administered Actiregularis for 15 days had decreased crying intensity (P = 0.000). When the difference in breastfeeding rates between the groups was significant at the 4th and 6th months (P = 0.044; P = 0.035). There was no difference in anthropometric values except the babies' weights at the 6th month. (P < 0.001).</p><p><strong>Conclusion: </strong>Infants treated with Actiregularis, which was added to their mothers' diet for 15 days, showed a decrease in the frequency of crying, and the difference in breastfeeding rates between the groups was significant at the 4th and 6th months. There was no difference in anthropometric values except the babies' weights at the 6th month.</p><p><strong>Clinical trials registration: </strong>NCT04374955 (https://clinicaltrials.gov/ct2/show/).</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alcohol consumption during pregnancy by women from southern Brazil: a cross-sectional study.","authors":"Laira Francielle Ferreira Zottis, Mateus Arenhardt de Souza, Jéssica Karine Hartmann, Thiago Kenji Kurogi Gama, Laís Borges Rizental, Anita Machado Maciel, Merialine Gresele, Ernani Bohrer da Rosa, Maurício Rouvel Nunes, Juliana Trevisan da Rocha, Jorge Alberto Bianchi Telles, André Campos da Cunha, Paulo Ricardo Gazzola Zen, Rafael Fabiano Machado Rosa","doi":"10.1590/1516-3180.2023.0186.R1.08022024","DOIUrl":"10.1590/1516-3180.2023.0186.R1.08022024","url":null,"abstract":"<p><strong>Background: </strong>Some maternal characteristics are related to alcohol intake during pregnancy, which irreversibly compromises the maternal-fetal binomial integrity.</p><p><strong>Objectives: </strong>To identify the frequency, impact, and factors associated with alcohol consumption during pregnancy.</p><p><strong>Design and setting: </strong>A cross-sectional study was performed at the Hospital Materno Infantil Presidente Vargas (HMIPV) in Porto Alegre/RS between March and December 2016.</p><p><strong>Methods: </strong>A structured questionnaire was administered along with a medical records review. They refer to the maternal sociodemographic and gestational status, alcohol consumption patterns, and characteristics of the fetus/newborn. In the statistical analysis, P values < 0.05 were considered significant.</p><p><strong>Results: </strong>The frequency of alcohol intake was 37.3%; this was characterized by the consumption of fermented beverages (89.3%), especially during the first trimester (79.6%). Risky consumption (high and/or early) occurred for 30.2% of participants. Risk factors associated with maternal alcohol consumption during pregnancy were tobacco use (P < 0.001) and abortion attempt (P = 0.023). Living with a partner (P = 0.002) and planning pregnancy (P = 0.009) were protective factors. Risky consumption was related to all of the aforementioned variables as well as threatened abortion (P = 0.023).</p><p><strong>Conclusions: </strong>Alcohol intake during pregnancy is common and affects nearly one-third of pregnant women. Knowledge of the population at risk and protective factors is essential for the development of campaigns that seek to reduce consumption and, therefore, its consequences for the mother and fetus.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034884/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison between use of a pleural drainage system with flutter valve and a conventional water-seal drainage system after lung resection: a randomized prospective study.","authors":"Rodrigo Caetano de Souza, Lilianne Louise Silva de Morais, Mario Claudio Ghefter, Juliana Pereira Franceschini, Fernando Campos Gomes Pinto","doi":"10.1590/1516-3180.2023.0224.R1.08022024","DOIUrl":"10.1590/1516-3180.2023.0224.R1.08022024","url":null,"abstract":"<p><strong>Background: </strong>There is still a debate regarding the most appropriate pleural collector model to ensure a short hospital stay and minimum complications.</p><p><strong>Objectives: </strong>To study aimed to compare the time of air leak, time to drain removal, and length of hospital stay between a standard water-seal drainage system and a pleural collector system with a unidirectional flutter valve and rigid chamber.</p><p><strong>Design and setting: </strong>A randomized prospective clinical trial was conducted at a high-complexity hospital in São Paulo, Brazil.</p><p><strong>Methods: </strong>Sixty-three patients who underwent open or video-assisted thoracoscopic lung wedge resection or lobectomy were randomized into two groups, according to the drainage system used: the control group (WS), which used a conventional water-seal pleural collector, and the study group (V), which used a flutter valve device (Sinapi® Model XL1000®). Variables related to the drainage system, time of air leak, time to drain removal, and time spent in hospital were compared between the groups.</p><p><strong>Results: </strong>Most patients (63%) had lung cancer. No differences were observed between the groups in the time of air leak or time spent hospitalized. The time to drain removal was slightly shorter in the V group; however, the difference was not statistically significant. Seven patients presented with surgery-related complications: five and two in the WS and V groups, respectively.</p><p><strong>Conclusions: </strong>Air leak, time to drain removal, and time spent in the hospital were similar between the groups. The system used in the V group resulted in no adverse events and was safe.</p><p><strong>Registration: </strong>RBR-85qq6jc (https://ensaiosclinicos.gov.br/rg/RBR-85qq6jc).</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140861174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive and social adaptation in autism spectrum disorder: A prospective cohort study.","authors":"Márcia Regina Fumagalli Marteleto, Jacy Perissinoto","doi":"10.1590/1516-3180.2023.0184.R1.16022024","DOIUrl":"10.1590/1516-3180.2023.0184.R1.16022024","url":null,"abstract":"<p><strong>Background: </strong>During development, children face a number of demands and cognitive, behavioral, and social challenges necessary for growth. Cognitive skills make individuals competent and allow them to interact with their environment.</p><p><strong>Objective: </strong>To identify the cognitive skills that promote better social insertion in children with autism spectrum disorder within 12 months.</p><p><strong>Design and setting: </strong>Prospective cohort study.</p><p><strong>Methods: </strong>In this study, 21 children aged 3-12 years were assessed, and their mothers were interviewed. Children were enrolled in regular or special autistic schools. Twelve months after the first assessment, the same children participated in the second assessment. In individual interviews, mothers provided data by answering the Vineland Adaptive Behavior Scale. Each child was assessed individually using the fourth edition of the Stanford Binet Intelligence Scale 4th Edition.</p><p><strong>Results: </strong>In the first assessment, the Stanford Binet areas and total scores correlated with the communication domains, daily life abilities, socialization, and total score of the Vineland Scale. After 12 months, a correlation was observed between the Stanford Binet areas and the total and communication domains, daily life abilities, socialization, motor abilities, and total score on the Vineland Scale.</p><p><strong>Conclusion: </strong>Logic mathematics and memory promote better social insertion in children with autism spectrum disorder. General cognitive ability promotes communication.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11034700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140866995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Organ donation consent after death.","authors":"Valter Duro Garcia, José Osmar Medina de Abreu Pestana, Paulo Manuel Pêgo-Fernandes","doi":"10.1590/1516-3180.2024.1422.120324","DOIUrl":"https://doi.org/10.1590/1516-3180.2024.1422.120324","url":null,"abstract":"","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140873345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Portuguese Advance Directives-a twist against futility? A cross sectional study.","authors":"Catarina Sampaio Martins, Rui Nunes","doi":"10.1590/1516-3180.2022.0537.R2.201023","DOIUrl":"10.1590/1516-3180.2022.0537.R2.201023","url":null,"abstract":"<p><strong>Background: </strong>Advance Directive documents allow citizens to choose the treatments they want for end-of-life care without considering therapeutic futility.</p><p><strong>Objectives: </strong>To analyze patients' and caregivers' answers to Advance Directives and understand their expectations regarding their decisions.</p><p><strong>Design and setting: </strong>This study analyzed participants' answers to a previously published trial, conceived to test the document's efficacy as a communication tool.</p><p><strong>Methods: </strong>Sixty palliative patients and 60 caregivers (n = 120) registered their preferences in the Advance Directive document and expressed their expectations regarding whether to receive the chosen treatments.</p><p><strong>Results: </strong>In the patient and caregiver groups, 30% and 23.3% wanted to receive cardiorespiratory resuscitation; 23.3% and 25% wanted to receive artificial organ support; and 40% and 35% chose to receive artificial feeding and hydration, respectively. The participants ignored the concept of therapeutic futility and expected to receive invasive treatments. The concept of therapeutic futility should be addressed and discussed with both the patients and caregivers. Legal Advanced Directive documents should be made clear to reduce misinterpretations and potential legal conflicts.</p><p><strong>Conclusion: </strong>The authors suggest that all citizens should be clarified regarding the futility concept before filling out the Advance Directives and propose a grammatical change in the document, replacing the phrase \"Health Care to Receive / Not to Receive\" with the sentence \"Health Care to Accept / Refuse\" so that patients cannot demand treatments, but instead accept or refuse the proposed therapeutic plans.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov ID NCT05090072.</p><p><strong>Url: </strong>https://clinicaltrials.gov/ct2/show/NCT05090072.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10962926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translation and cultural adaptation of the Positive Aspects of Caregiving Scale for caregivers of people living with dementia in Brazilian context: a methodological study.","authors":"Sofia Cristina Iost Pavarini, Aline Cristina Martins Gratão, Camila Rafael Ferreira Campos, Diana Quirino Monteiro, Elizabeth Joan Barham, Fabiana de Souza Orlandi, Gabriela Martins, Gustavo Carrijo Barbosa, Keila Cristianne Trindade da Cruz, Larissa Corrêa, Luana Aparecida da Rocha, Ludmyla Caroline de Souza Alves, Ana Carolina Ottaviani","doi":"10.1590/1516-3180.2023.0325.R1.23012024","DOIUrl":"10.1590/1516-3180.2023.0325.R1.23012024","url":null,"abstract":"<p><strong>Background: </strong>The Positive Aspects of Caregiving (PAC) scale is used to assess psychosocial benefits provided to caregivers by the task of caring. The PAC scale consists of nine items, assessed using a five-point Likert scale, with higher values indicating greater positive perceptions and gains from the caregiving experience.</p><p><strong>Objective: </strong>To translate and culturally adapt the PAC scale for informal Brazilian caregivers of people with dementia.</p><p><strong>Design and setting: </strong>A methodological study was conducted at the Federal University of São Carlos.</p><p><strong>Methods: </strong>The following stages were carried out: Translation; Synthesis of the translations; Back-translation; Evaluation by an experts' committee; and Pre-test.</p><p><strong>Results: </strong>Two independent professionals translated the PAC scale. The consensus version was obtained by merging both translations, which were back-translated into English by a third translator. The expert committee comprised three specialists in the area and project researchers. All scale items presented a Content Validity Index of 1 (CVI = 1.0), and thus remained in the pre-final version of the instrument. The instrument was pre-tested with seven caregivers of people with dementia, the majority of whom were women (57.1%), with a degree of kinship corresponding to sons/daughters (57.1%) and an average age of 55.2 (± 4.1) years. The caregivers considered it clear and understandable and made no suggestions for changes.</p><p><strong>Conclusion: </strong>The PAC scale was translated and culturally adapted for use by informal caregivers of people with dementia in Brazil. However, a psychometric analysis of the instrument is necessary to provide normative data for this population group.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10950309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140177375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isotemporal substitution analysis of time between sleep, sedentary behavior, and physical activity on depressive symptoms in older adults: a cross-sectional study.","authors":"Joilson Meneguci, Lucas Lima Galvão, Sheilla Tribess, Cíntia Aparecida Garcia Meneguci, Jair Sindra Virtuoso Júnior","doi":"10.1590/1516-3180.2023.0144.R2.04122023","DOIUrl":"10.1590/1516-3180.2023.0144.R2.04122023","url":null,"abstract":"<p><strong>Background: </strong>Compared to young individuals, older adults participate more in sedentary behavior (SB) and less in physical activity (PA). These behaviors are associated with numerous adverse health factors.</p><p><strong>Objective: </strong>The purpose of the study was to examine the hypothetical effects of substituting time spent sleeping, performing SB, and performing moderate-to-vigorous physical activity (MVPA) on depressive symptomatology in older adults.</p><p><strong>Design and setting: </strong>An analytical cross-sectional study employing exploratory survey methods was conducted in the city of Alcobaça in the state of Bahia, Brazil.</p><p><strong>Methods: </strong>The study included 473 older adults who answered a structured questionnaire during an interview. Exposure time to SB and PA level were assessed using the International Physical Activity Questionnaire, and depressive symptoms were analyzed using the short version of the Geriatric Depression Scale. An isotemporal replacement model was used to evaluate the effects of different SB sessions on depressive symptomatology.</p><p><strong>Results: </strong>An increase in the risk of depressive symptoms was observed when MVPA and sleep time were substituted for the same SB time at all times tested, with maximum values of 40% and 20%, respectively. Opposite substitution of MVPA and sleep time increments reduced the risk of depressive symptomatology by 28% and 17%, respectively.</p><p><strong>Conclusions: </strong>The results of the present study indicate that replacing SB with the same amount of sleep or MVPA may reduce depressive symptoms. The longer the reallocation time, the greater are the benefits.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10950321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140177374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report of scrub typhus complicated by hypokalemia and multiple organ dysfunction syndrome.","authors":"Li Chen, Yi Deng, Peiying Huang, Sisi Lei, Shuling Liu, Weitao Lin, Zhishang Li, Jing Zeng, Miaochun Huang, Qiuping Huang, Qihua Wu, Haobo Zhang, Bojun Chen","doi":"10.1590/1516-3180.2023.0142.R1.08122023","DOIUrl":"10.1590/1516-3180.2023.0142.R1.08122023","url":null,"abstract":"<p><strong>Context: </strong>Scrub typhus, caused by Orientia tsutsugamushi, has a wide range of clinical manifestations, including meningoencephalitis, acute renal failure, pneumonitis, myocarditis, and septic shock. However, there are no documented cases of scrub typhus with hypokalemia. In this report, we present a case of scrub typhus with hypokalemia and multiple organ failure syndrome, highlighting the importance of electrolyte imbalance in patients with scrub typhus.</p><p><strong>Case report: </strong>A 59-year-old woman presented to the emergency department with abdominal pain that had been present for 1 day. On admission, the physical examination and laboratory test results indicated that the patient had renal, liver, and circulatory failure, and hypokalemia. She developed meningitis and disseminated intravascular coagulation during hospitalization. She recovered with appropriate management, and was discharged on day 17.</p><p><strong>Conclusion: </strong>This report highlights the potential for atypical presentations of scrub typhus, including a previously undocumented association with hypokalemia. Although the contribution of hypokalemia to the patient's clinical course remains uncertain, this case underscores the importance of considering electrolyte imbalance in the management of patients with scrub typhus. Further research is warranted to better understand the relationship between scrub typhus and electrolyte imbalance.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10926963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the effect of the structural model of active aging on the self-assessment of quality of life among older people: A cross-sectional and analytical study.","authors":"Nayara Gomes Nunes Oliveira, Alisson Fernandes Bolina, Vanderlei José Haas, Darlene Mara Dos Santos Tavares","doi":"10.1590/1516-3180.2022.0609.R1.230523","DOIUrl":"10.1590/1516-3180.2022.0609.R1.230523","url":null,"abstract":"<p><strong>Background: </strong>Although studies have examined the relationship between variables associated with active aging and quality of life (QoL), no studies have been identified to have investigated the effect of a structural model of active aging on QoL in a representative sample of older people in the community.</p><p><strong>Objective: </strong>To measure the domains and facets of QoL in older people and identify the effect of the structural model of active aging on the self-assessment of QoL.</p><p><strong>Design and setting: </strong>This cross-sectional analytical study included 957 older people living in urban areas. Data were collected from households using validated instruments between March and June 2018. Descriptive, confirmatory factor, and structural equation modeling analyses were performed.</p><p><strong>Results: </strong>Most older people self-rated their QoL as good (58.7%), and the highest mean scores were for the social relationships domain (70.12 ± 15.4) and the death and dying facet (75.43 ± 26.7). In contrast, the lowest mean scores were for the physical domains (64.41 ± 17.1) and social participation (67.20 ± 16.2) facets. It was found that active aging explained 50% of the variation in self-assessed QoL and directly and positively affected this outcome (λ = 0.70; P < 0.001).</p><p><strong>Conclusion: </strong>Active aging had a direct and positive effect on the self-assessment of QoL, indicating that the more individuals actively aged, the better the self-assessment of QoL.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10926965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140111999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}