Sao Paulo Medical Journal最新文献

{"title":"Frequency of scapular dyskinesis and its relationship with disease parameters in patients with ankylosing spondylitis: a cross-sectional study.","authors":"Sertaç Ketenci, Bora Uzuner, Dilek Durmuş, Deniz Şahinkaya, Muharrem Yüksel, Ahmet Kıvanç Cengiz","doi":"10.1590/1516-3180.2024.0136.R1.13082024","DOIUrl":"https://doi.org/10.1590/1516-3180.2024.0136.R1.13082024","url":null,"abstract":"<p><strong>Background: </strong>Scapular dyskinesis (SD) is a condition associated with impaired scapular movement caused by cervical, shoulder, and postural abnormalities.</p><p><strong>Objective: </strong>The aim of this study was to determine the frequency of SD in patients with ankylosing spondylitis (AS).</p><p><strong>Design and setting: </strong>A cross-sectional study was conducted at Ondokuz Mayıs University, Samsun, Turkey.</p><p><strong>Methods: </strong>One hundred patients with AS but without shoulder involvement (74 males and 26 females) and 50 healthy controls (35 males and 15 females) were included in the study. The patients were divided into two groups: patients with and without SD. SD was assessed using the Scapular Dyskinesis Test and Lateral Scapular Slide Test. Disease activity, spinal mobility, and chest expansion were also measured. The severity of enthesitis was evaluated using the Spondyloarthritis Research Consortium of Canada index.</p><p><strong>Results: </strong>There were significant differences between the two groups of patients with AS, those with SD, and those without SD in terms of age, chest expansion, and the Bath Ankylosing Spondylitis Metrology Index (BASMI) scores (P < 0.05). The groups differed significantly in terms of hip, thoracic, and lumbar involvement (P < 0.05). The BASMI score was a significant variable affecting SD (P < 0.05). No cases of SD were observed in the control group.</p><p><strong>Conclusion: </strong>While there were no significant differences in disease activity and enthesitis scores between patients with and without SD, differences were detected in mobility parameters. Since shoulder examinations of the patients were normal, it can be inferred that SD occurred because of the involvement of the scapulothoracic joints and thoracic spine.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2024136"},"PeriodicalIF":1.3,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of healthcare-associated infections in Brazil: multi-hospital point prevalence using a matched case-control study.","authors":"Luiz Gustavo Machado, Daiane Silva Resende, Paola Amaral de Campos, Iara Rossi, Melina Lorraine Ferreira, Iolanda Alves Braga, Caio Augusto Martins Aires, Maria Tereza Freitas Tenório, Paulo Pinto Gontijo-Filho, Sabrina Royer, Rosineide Marques Ribas","doi":"10.1590/1516-3180.2023.0307.R1.03072024","DOIUrl":"https://doi.org/10.1590/1516-3180.2023.0307.R1.03072024","url":null,"abstract":"<p><strong>Background: </strong>Healthcare-associated infections (HAIs) have a significant impact on patient care worldwide and have serious implications for the Brazilian healthcare system.</p><p><strong>Objectives: </strong>This study aimed to describe the trends in HAIs in adult intensive care units (ICUs) using data from a national point-prevalence survey.</p><p><strong>Design and setting: </strong>A point-prevalence study was conducted in 2019 across adult intensive ICUs in large acute care hospitals in Brazil.</p><p><strong>Methods: </strong>A matched case-control study was performed to assess the risk factors associated with the development of infection.</p><p><strong>Results: </strong>A total of 386 patients from 15 hospitals were studied, of whom 102 (26.4%; 102/386) were infected, and 76.5% had at least one ICU-acquired infection. In clinical-surgical ICUs (CSU), the prevalence of infections acquired in the unit was 77.9%, whereas in Coronary ICUs (COU), it was 68.7%. There was a predominance of pneumonia (51.0%), mainly caused by Gram-negative non-fermenters, and bloodstream infections (34.4%), predominantly caused by coagulase-negative Staphylococcus (CoNS). In the risk factor analysis, cancer and general antimicrobial use were independently associated.</p><p><strong>Conclusion: </strong>This study found a high burden of HAIs in adult ICUs in Brazil, mainly associated with the high use of antibiotics for infections and a worse prognosis.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2023307"},"PeriodicalIF":1.3,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cluster of factors related to metabolic changes in older individuals: a cross-sectional study.","authors":"Clarice Alves Dos Santos, Mariana Alves Dos Santos, Manuela Alves Dos Santos, Milena Fernandez Dias, Lélia Renata Carneiro Vasconcelos, Saulo Vasconcelos Rocha","doi":"10.1590/1516.3180.2023.0283.R1.30082024","DOIUrl":"https://doi.org/10.1590/1516.3180.2023.0283.R1.30082024","url":null,"abstract":"<p><strong>Background: </strong>Exposure to multiple risk factors related to metabolic changes can negatively affect the health status of older individuals.</p><p><strong>Objective: </strong>To investigate the clustering of factors related to metabolic changes in older individuals.</p><p><strong>Design and setting: </strong>This was a cross-sectional study involving 287 older individuals (≥ 60 years old) enrolled in the Family Health Strategy in the municipality of Ibicuí, state of Bahia.</p><p><strong>Methods: </strong>Factors associated with metabolic changes were abdominal obesity, self-reported diabetes, high blood pressure, sedentary behavior, and physical inactivity. Clustering was defined by an observed-to-expected prevalence (O/E) ratio greater than 1.20. The association between these factors was analyzed using multiple logistic regression.</p><p><strong>Results: </strong>A total of seven clusters were identified with a predominance of diabetes, hypertension, sedentary behavior, and abdominal obesity (O/E = 2.28). Older adults were more likely to present with physical inactivity, diabetes, blood pressure, and sedentary behavior simultaneously (Odds Ratio [OR] = 7.78; 95% confidence interval [CI] = 1.25-48.42). Negative health perception was associated with the combination of high blood pressure, sedentary behavior, and abdominal obesity (OR = 0.23; 95%CI = 0.25-0.92); female sex with the cluster of physical inactivity and abdominal obesity (OR = 0.12; 95%CI = 0.04-0.35); and the occurrence of physical inactivity without the presence of other factors (OR = 3.87; 95%CI = 1.66-8.99).</p><p><strong>Conclusions: </strong>The combination of risk factors related to metabolic changes represents a greater probability of health problems than individual factors. Therefore, investigating the association between these factors will help in planning targeted interventions.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2023283"},"PeriodicalIF":1.3,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of depression on patients suffering from ankylosing spondylitis: a comparative study.","authors":"Antonio Cortés-Rodríguez, Lisa Alves-Gomes, Marta Losa-Iglesias, Juan Gómez-Salgado, Ricardo Becerro-de-Bengoa-Vallejo, Miguel Ángel Saavedra-García, Daniel López-López, Ana María Jiménez-Cebrián","doi":"10.1590/1516-3180.2024.0177.R1.16102024","DOIUrl":"10.1590/1516-3180.2024.0177.R1.16102024","url":null,"abstract":"<p><strong>Background: </strong>Ankylosing spondylitis (AS) is a sustained inflammatory pathology that manifests as increasing rigidity and a continuous decline in spinal flexibility, leading to increasing lumbar pain during rest.</p><p><strong>Objectives: </strong>This study primarily aimed to evaluate depression assessments using the Beck Depression Inventory (BDI) and delineate depressive symptomatology in patients diagnosed with AS compared to those without this condition.</p><p><strong>Design and setting: </strong>A comparative study was conducted in Medical Centers in Málaga, Spain.</p><p><strong>Methods: </strong>A cohort of 102 participants, with a mean age of 46,80 ± 10,54 years, was divided into two sets: 51 individuals diagnosed with AS (cases) and another 51 without AS (controls), each harmonized across variables such as body mass index, age, and sex. Demographic variables were systematically gathered from each participant, and the BDI responses were accurately recorded and subsequently analyzed for comparison.</p><p><strong>Results: </strong>Of the total sample, the sex distribution was 29.4% male and 70.6% female. BDI scores were higher for the AS group (19.25 ± 15.5) than for the control group (5.33 ± 7). Notably, there were clear statistical differences (P < 0.01) in the BDI categories, with elevated levels observed in participants with AS.</p><p><strong>Conclusion: </strong>Individuals with AS experienced higher levels of depression than those without AS. Furthermore, there were sex differences within the case group, with a higher percentage of women than men at any level of depression. Notably, there was a moderate inverse correlation between the number of years since diagnosis and depression level.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2024177"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11974190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of alcohol consumption and the associated factors among students at a Brazilian public university: a cross-sectional study.","authors":"Lucas Carrara do Amaral, Lucas Lima Galvão, Douglas Assis Teles Santos, Gustavo Conti Teixeira Costa, Marilia Santos Andrade, Rodrigo Luiz Vancini, Katja Weiss, Beat Knechtle, Marciana Gonçalves Farinha, Claudio Andre Barbosa de Lira","doi":"10.1590/1516-3138.2023.0383.R1.03072024","DOIUrl":"10.1590/1516-3138.2023.0383.R1.03072024","url":null,"abstract":"<p><strong>Background: </strong>The World Health Organization estimated that approximately 43% of the global population consumes alcohol, with an average annual consumption of 4.6 L per person. However, little is known about the factors influencing alcohol intake among students.</p><p><strong>Objectives: </strong>This study aimed to determine the factors that influence alcohol intake in students at a Brazilian public institution.</p><p><strong>Design and setting: </strong>This cross-sectional study was conducted at a public university in the Brazilian Midwest.</p><p><strong>Methods: </strong>In total, 348 Brazilian university students (124 men and 224 women; convenience sample) were recruited. The alcohol use disorder identification test (AUDIT) was used to examine alcohol use, the habitual physical activity questionnaire (Baecke) was used to assess physical activity levels, and the Brazil Economic Classification Standard Criterion was used to assess socioeconomic status. A generalized linear model (GLM) with a 95% confidence interval (CI) and odds ratio (OR) estimation was constructed using the Tweedie probability distribution and log link function, with AUDIT questionnaire scores as the dependent variable.</p><p><strong>Results: </strong>The prevalence of excessive alcohol consumption was 18.7% (9.8% in men and 8.9% in women). The GLM analysis indicated that being single and attending an agricultural science course increased the likelihood of excessive alcohol intake; however, living with family or alone had a protective effect. Being single and pursuing a course in agricultural science increased the likelihood of binge drinking.</p><p><strong>Conclusion: </strong>Universities and families can use the study findings to develop initiatives aimed at enhancing students' understanding of the harmful effects of alcohol, particularly among agricultural science students.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2023383"},"PeriodicalIF":1.3,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11974194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hostages to Social Networks and Mental Health.","authors":"Carmita Helena Najjar Abdo, Paulo Manuel Pêgo-Fernandes","doi":"10.1590/1516-3180.2025.1432.13122024","DOIUrl":"10.1590/1516-3180.2025.1432.13122024","url":null,"abstract":"","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e20251432"},"PeriodicalIF":1.3,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rating of perceived exertion versus heart rate for isometric exercise prescription: Reliability and agreement study.","authors":"Paulo Henrique de Melo, Anderson Cavalcante, Jessika Karla Tavares do Nascimento Faustino Silva, José Lucas Porto Aguiar, Jefferson Maxwell De Farias Silva, Theo Victor Alves Soares Rêgo, Raphael Mendes Ritti-Dias, Breno Quintella Farah","doi":"10.1590/1516-3180.2024.0092.R1.29072024","DOIUrl":"10.1590/1516-3180.2024.0092.R1.29072024","url":null,"abstract":"<p><strong>Background: </strong>Previous studies have shown that isometric exercise training reduces systolic blood pressure by approximately 8 mmHg and diastolic blood pressure by approximately 4 mmHg in both normotensive and hypertensive individuals. However, the prescription of isometric exercises can be based on the rating of perceived exertion (RPE) or heart rate (HR) obtained during the maximal incremental isometry test. The reliability and agreement of this test have not been assessed.</p><p><strong>Objectives: </strong>To analyze the reliability and agreement indicators of HR and RPE during isometric wall squat incremental tests.</p><p><strong>Design and setting: </strong>A reliability and agreement study was conducted at Universidade Federal de Pernambuco.</p><p><strong>Methods: </strong>Twenty-eight healthy subjects (54% men, 26 ± 5 years) performed two isometric wall squat incremental tests. The test began with a knee joint angle of 135° (knee and leg) progressively reduced by 10° at each stage. Each stage lasts 2 minutes or until voluntary exhaustion. The HR and RPE were obtained during the tests. Reliability and agreement were established using test-retest (paired t-test or Wilcoxon test), intraclass correlation coefficient (ICC), standard error of measurement (SEM), coefficient of variation (CV), and Bland-Altman plots.</p><p><strong>Results: </strong>The HR and RPE increased significantly during both tests. The HR and RPE at each stage were similar between the two test sessions (P > 0.05). Both HRmax (ICC: 0.695, P = 0.002, SEM = 8.1 bpm and CV = 5.8%) and RPEmax (ICC: 0.525, P = 0.036, SEM = 0.4 and CV = 3.6%) presented similar reliability indicators, and no statistically significant differences were obtained between the two test sessions (P > 0.05). The Bland-Altman plots indicated good agreement between HRmax and RPEmax.</p><p><strong>Conclusion: </strong>HR and RPE showed similar reliability and agreement during the isometric wall squat incremental test.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2024092"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922297/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical activity and factors associated with the costs of low back pain among adults after 18 months of follow-up: a cohort study.","authors":"Everton Alex Carvalho Zanuto, Valter Penna, Cristiano Rocha da Silva, Enio Ricardo Vaz Ronque, Ruben de Faria Negrão Filho, Robson Chacon Castoldi, Jamile Sanches Codogno, Rômulo Araújo Fernandes","doi":"10.1590/1516-3180.2023.0343.R1.03072024","DOIUrl":"10.1590/1516-3180.2023.0343.R1.03072024","url":null,"abstract":"<p><strong>Background: </strong>Chronic low back pain (CLBP) is a substantial health problem that causes considerable economic losses. Several studies have demonstrated the protective effect of habitual physical activity; however, little data are available regarding its impact on the costs associated with CLBP.</p><p><strong>Objectives: </strong>The primary aim of this study was to analyze the costs of CLBP in the Brazilian Health System and associated factors among adults.</p><p><strong>Design and setting: </strong>An 18-month cohort study was conducted in two basic health units in Presidente Prudente (SP), Brazil.</p><p><strong>Methods: </strong>A total of 198 patients were interviewed and evaluated four times: at baseline, with retrospective data covering the previous 12 months, and at six, 12, and 18 months. The Nordic and Baecke questionnaires were used to classify CLBP, and the Baecke questionnaire was used for physical activity assessment. The costs were calculated by reviewing the demand for services from medical records. Body mass index (kg/m2) was determined using body mass and height values collected during the interviews. The questionnaire included confounding variables, such as sex, age, ethnicity, and socioeconomic status.</p><p><strong>Results: </strong>A high prevalence of CLBP was observed, which was associated with female sex and younger age. CLBP resulted in high costs for medical consultations (without: US$ 34.25 ± 23.21; with: US$ 39.62 ± 27.25; P = 0.049), while cycling was negatively associated with costs (rho = -0.289; P = 0.049).</p><p><strong>Conclusion: </strong>Lower back pain was associated with higher costs of medical consultations, while cycling was associated with reduced costs.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2023343"},"PeriodicalIF":1.3,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11922298/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short version of the Problem Areas in Diabetes scale(PAID-13) in Brazilian patients with diabetes: a structural and criterion validity study.","authors":"Daniel Santos Rocha, Almir Vieira Dibai-Filho, Abraão Albino Mendes Júnior, Nataly Borges da Costa Pinto, Kaiser Salgado Neves, Carlos Eduardo Neves Amorim, Plínio da Cunha Leal, Janaina de Oliveira Brito-Monzani, Daniela Bassi-Dibai","doi":"10.1590/1516-3180.2024.0109.R1.03072024","DOIUrl":"10.1590/1516-3180.2024.0109.R1.03072024","url":null,"abstract":"<p><strong>Background: </strong>The Problem Areas in Diabetes scale (PAID) is used to measure emotional distress levels related to diabetes mellitus (DM). However, consensus on its internal structure is lacking.</p><p><strong>Objectives: </strong>To compare the different internal structures of the PAID and propose a shortened version for Brazilian patients with diabetes.</p><p><strong>Design and setting: </strong>Structural and criterion validity study.</p><p><strong>Methods: </strong>We included Brazilian patients with type 1 DM (DM1) and type 2 DM (DM2) in this study. In accordance with the international consensus recommendations, we assessed the structural validity using confirmatory factor analysis (CFA) and used the following indices to evaluate model fit: root mean square error of approximation (RMSEA), comparative fit index (CFI), Tucker-Lewis index (TLI), standardized root mean square residual (SRMR), chi-square/degrees of freedom (DF), Akaike information criterion (AIC) and sample-size adjusted Bayesian information criterion (SABIC). Modification indices and factor loadings were used to reduce the number of items.</p><p><strong>Results: </strong>One hundred eighty-five patients, most of whom included women with DM2, participated in the study. The reduction in the PAID generated a unidimensional structure with 13 items (PAID-13). The PAID-13 presented the best-fit indices (chi-square/DF = 2.15, CFI = 0.989, TLI = 0.986, RMSEA = 0.079, and SRMR = 0.049). When the PAID versions with 13 and 20 items (original version) were correlated, a strong correlation was observed (rho = 0.941, P < 0.001).</p><p><strong>Conclusion: </strong>The short version of the PAID scale with 13 items presented a more appropriate internal structure for Brazilian patients with diabetes.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2024109"},"PeriodicalIF":1.3,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11913428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis prediction of prostate and testicular cancer mortality using machine learning: accuracy study.","authors":"Aurélio Gomes de Albuquerque Neto, David Medeiros Nery, João Paulo Araújo Braz, Carla Ferreira do Nascimento, Tiago Almeida de Oliveira, Brígida Gabriele Albuquerque Barra, Leonardo Thiago Duarte Barreto Nobre, Diego Bonfada, Janine Karla França da Silva Braz","doi":"10.1590/1516-3180.2024.0080.03072024","DOIUrl":"10.1590/1516-3180.2024.0080.03072024","url":null,"abstract":"<p><strong>Background: </strong>The mortality rates of prostate and testicular cancer are higher mortality in the northeast region.</p><p><strong>Objective: </strong>We aimed to compare the efficacy of machine learning libraries in predicting testicular and prostate cancer mortality.</p><p><strong>Design and setting: </strong>A comparative analysis of the pyMannKendall and Prophet machine-learning algorithms was conducted to develop predictive models using data from DATASUS (TabNet) to Caicó (Brazil) and Rio Grande do Norte (Brazil).</p><p><strong>Methods: </strong>Data on prostate and testicular cancer mortality in men from 2000 to 2019 were collected. The prediction accuracy of the Prophet algorithm was evaluated using the mean squared error (MSE), the root mean squared error and analyzed using the pyMannKendall, and Prophet libraries.</p><p><strong>Results: </strong>The research data were made publicly available on GitHub. The machine test confirmed the accuracy of the predictions, with the root MSE (RMSE) values closely matching the observed data for Caicó (RMSE = 2.46) and Rio Grande do Norte (RMSE = 22.85). The Prophet algorithm predicted an increase in prostate cancer mortality by 2030 in Caicó and Rio Grande do Norte. This prediction was corroborated by the pyMannKendall analysis, which indicated a 99% probability of a rising mortality trend in Caicó (P < 0.01; tau = 0.586; intercept = 2.59) and Rio Grande do Norte (P = 2.06; tau = 0.84, and intercept = 119.63). For testicular cancer, no significant mortality trend was identified by Prophet or pyMann-Kendall.</p><p><strong>Conclusions: </strong>Libraries are reliable tools for predicting mortality, providing support for strategic health planning, and implementing preventive measures to ensure men's health. Addressing the gender gap in DATASUS is essential.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2024080"},"PeriodicalIF":1.3,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143505707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}