Sao Paulo Medical Journal最新文献

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Stroke in older people in Brazil: prevalence, associated factors, limitations and care practices. A cross-sectional study. 巴西老年人中风:患病率、相关因素、局限性和护理实践横断面研究。
IF 1.3 4区 医学
Sao Paulo Medical Journal Pub Date : 2025-05-26 eCollection Date: 2025-01-01 DOI: 10.1590/1516-3180.2024.0132.R1.13082024
Priscila Maria Stolses Bergamo Francisco, Athos Paixão Silva Santos, Daniela de Assumpção, Aldiane Gomes de Macedo Bacurau
{"title":"Stroke in older people in Brazil: prevalence, associated factors, limitations and care practices. A cross-sectional study.","authors":"Priscila Maria Stolses Bergamo Francisco, Athos Paixão Silva Santos, Daniela de Assumpção, Aldiane Gomes de Macedo Bacurau","doi":"10.1590/1516-3180.2024.0132.R1.13082024","DOIUrl":"10.1590/1516-3180.2024.0132.R1.13082024","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular diseases, especially ischemic heart disease and stroke, are the main causes of mortality in older people.</p><p><strong>Objectives: </strong>To estimate the prevalence of stroke in older people in Brazil, we investigated its associations with sociodemographic factors, health-related behaviors, chronic diseases, body mass index and self-rated health and determined the frequency of limitations related to disease and care practices.</p><p><strong>Design and setting: </strong>This population-based, cross-sectional study used data from the 2019 Brazilian National Health Survey.</p><p><strong>Methods: </strong>This study included older people aged ≥ 60 years (n = 22,728) who answered the question, \"Has any doctor ever given you a diagnosis of stroke?\" Adjusted odds ratios were estimated using logistic regression.</p><p><strong>Results: </strong>The prevalence of stroke was 5.6% (95% confidence interval = 5.1-6.1) and was higher in men, individuals aged ≥ 70 years, those with a lower income, those without health insurance, ex-smokers, physically inactive individuals, those with excess weight/obesity, those who rated their own health as fair/poor/very poor and those who reported hypertension, diabetes, kidney failure, depression and heart disease. The most adopted care practices were follow-ups by a healthcare provider (60.8%), medication use (59.3%) and diet (47.2%). Only 17.0% of patients underwent physiotherapy, and 53.7% reported limitations in habitual activities.</p><p><strong>Conclusions: </strong>Subgroups of people more affected by stroke were identified, which included older individuals, those with lower socioeconomic status, ex-smokers and those with neuroendocrine and cardiovascular comorbidities. Less than 20% of patients underwent physiotherapy, which underscores the need to expand multidisciplinary care in the health network.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 3","pages":"e2024132"},"PeriodicalIF":1.3,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12105859/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144175472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Musculoskeletal rehabilitation in controlled trials: Is it correct to compare different types of exercise? 对照试验中的肌肉骨骼康复:比较不同类型的运动是否正确?
IF 1.3 4区 医学
Sao Paulo Medical Journal Pub Date : 2025-05-19 eCollection Date: 2025-01-01 DOI: 10.1590/1516-3180.2024.0374.29012025
André Pontes-Silva
{"title":"Musculoskeletal rehabilitation in controlled trials: Is it correct to compare different types of exercise?","authors":"André Pontes-Silva","doi":"10.1590/1516-3180.2024.0374.29012025","DOIUrl":"10.1590/1516-3180.2024.0374.29012025","url":null,"abstract":"<p><strong>Background: </strong>There are several randomized controlled trials (RCTs) in the literature on musculoskeletal rehabilitation that compare different types of exercise; however, the comparison is not relevant because the groups generally perform different physical efforts, and the researchers are not aware of this, nor do they control for the confounding variables.</p><p><strong>Objectives: </strong>To discuss the methods of comparison of different types of exercises in musculoskeletal rehabilitation.</p><p><strong>Design and settings: </strong>Short communication developed at the Universidade Federal de São Carlos (UFSCar), São Carlos (SP), Brazil.</p><p><strong>Methods: </strong>A narrative review of the motion cadence, time-under-tension, actual duration of an exercise session, and total physical effort was conducted.</p><p><strong>Results: </strong>To compare the different types of exercise, it is crucial that the parameters of the proposed exercises are the same between the groups, i.e., the exercise intensity, total physical effort, and actual duration of the exercise session.</p><p><strong>Conclusion: </strong>It is correct to compare different types of exercise, however, in the field of musculoskeletal rehabilitation, RCTs adequately controlled for these variables are lacking.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 3","pages":"e2024374"},"PeriodicalIF":1.3,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088647/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The urgent need for well-being programs in medical residencies in Brazil. 迫切需要在巴西的医疗住院医师福利计划。
IF 1.3 4区 医学
Sao Paulo Medical Journal Pub Date : 2025-05-19 eCollection Date: 2025-01-01 DOI: 10.1590/1516-3180.2023.0274.R1.29012025
Marcelo Bruno Generoso, Pedro Shiozawa, Ricardo Uchida, Marsal Sanches
{"title":"The urgent need for well-being programs in medical residencies in Brazil.","authors":"Marcelo Bruno Generoso, Pedro Shiozawa, Ricardo Uchida, Marsal Sanches","doi":"10.1590/1516-3180.2023.0274.R1.29012025","DOIUrl":"10.1590/1516-3180.2023.0274.R1.29012025","url":null,"abstract":"","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 3","pages":"e2023274"},"PeriodicalIF":1.3,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12088648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges in the integration of palliative care for patients with hematologic malignancies: an analysis of the surprise question in a prospective cohort study. 血液恶性肿瘤患者姑息治疗整合的挑战:一项前瞻性队列研究中意外问题的分析。
IF 1.3 4区 医学
Sao Paulo Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.1590/1516-3180.2024.0263.29012025
Alini Maria Orathes Ponte Silva, Diego Lopes Paim Miranda, David Pereira Ferreira, Camilla Correia de Araujo Pereira Campos, Edvan de Queiroz Crusoé, Felipe Feistauer Gomes, Thiago Favano, Marco Aurélio Salvino
{"title":"Challenges in the integration of palliative care for patients with hematologic malignancies: an analysis of the surprise question in a prospective cohort study.","authors":"Alini Maria Orathes Ponte Silva, Diego Lopes Paim Miranda, David Pereira Ferreira, Camilla Correia de Araujo Pereira Campos, Edvan de Queiroz Crusoé, Felipe Feistauer Gomes, Thiago Favano, Marco Aurélio Salvino","doi":"10.1590/1516-3180.2024.0263.29012025","DOIUrl":"https://doi.org/10.1590/1516-3180.2024.0263.29012025","url":null,"abstract":"<p><strong>Background: </strong>The Surprise Question (SQ), \"Would I be surprised if this patient were to die in the next 12 months?\", identifies patients at high risk of death who might benefit from palliative care (PC). However, little is known about its application in oncohematology.</p><p><strong>Objectives: </strong>To evaluate the performance of the SQ among inpatients with hematologic malignancies.</p><p><strong>Design and setting: </strong>A prospective cohort study was conducted between September and December 2021, including patients admitted to the Hematology Ward of the University Hospital in Salvador, Brazil.</p><p><strong>Methods: </strong>Physicians answered the SQ (not surprised (SQ+) or surprised (SQ-)). Mortality data were assessed after one year.</p><p><strong>Results: </strong>Eighty-one patients were included (56% SQ+ and 44% SQ-). At study closure, 36 patients (44%) had died. Median survival was 10.8 months (95%CI = 9.7-11.8) for SQ- and 5.6 months (95%CI = 4.1-7.1) for SQ+. Sensitivity was 86.1%, specificity 68.9%, positive predictive value 68.8%, negative predictive value 86.1%, and accuracy 76.5%. At the time of the interview, only 15 (18.5%) patients had consulted a PC specialist. By the study's end, 48% had been referred to PC. These patients had poorer performance status (82% vs. 40%, P < 0.001) and more advance care planning records (87% vs. 14%, P < 0.001).</p><p><strong>Conclusions: </strong>Despite the prognostic uncertainty of hematologic malignancies, the SQ effectively estimates mortality and serves as a valuable tool for early PC integration in oncohematology.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 3","pages":"e2024263"},"PeriodicalIF":1.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052263/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adherence to Guideline-Directed Medical Therapy Target in patients with heart failure and reduced ejection fraction: a cross-sectional study. 心力衰竭和射血分数降低患者坚持指南指导的药物治疗目标:一项横断面研究
IF 1.3 4区 医学
Sao Paulo Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.1590/1516-3180.2023.0315.R2.13082024
Fábio Figueirêdo Costa, Andréa Karoline Reis Chagas, Anna Cláudia Monteiro Luz Santos, Lívia Brito Oliveira, Alex Cleber Improta-Caria, Adriana Lopes Latado, Roque Aras Júnior
{"title":"Adherence to Guideline-Directed Medical Therapy Target in patients with heart failure and reduced ejection fraction: a cross-sectional study.","authors":"Fábio Figueirêdo Costa, Andréa Karoline Reis Chagas, Anna Cláudia Monteiro Luz Santos, Lívia Brito Oliveira, Alex Cleber Improta-Caria, Adriana Lopes Latado, Roque Aras Júnior","doi":"10.1590/1516-3180.2023.0315.R2.13082024","DOIUrl":"10.1590/1516-3180.2023.0315.R2.13082024","url":null,"abstract":"<p><strong>Background: </strong>Heart failure with reduced ejection fraction (HFrEF) represents a compelling cause of hospital morbidity and mortality in Brazil. There is low adherence to guideline-directed medical therapy (GDMT), which in turn, can result in higher morbidity and mortality.</p><p><strong>Objectives: </strong>The present study aims to evaluate adherence to GDMT in patients with HFrEF in a Brazilian University hospital service.</p><p><strong>Design and settings: </strong>Observational, cross-sectional, single-center study conducted at the Hospital Universitário Professor Edgard Santos (HUPES), Salvador, BA, Brazil.</p><p><strong>Methods: </strong>The study was conducted with convenience sampling at the cardiology outpatient clinic of a university hospital service. Patients with left ventricular ejection fraction (LVEF) < 40% who had reverse remodeling were excluded.</p><p><strong>Results: </strong>289 patients were included, with mean age 63 years, 54.7% were male, 56,4% mixed-race and 27,7% had Chagasic cardiomyopathy. 93.1% were prescribed ACEi, ARB or ARNi, 95.8% betablockers, 69.2% spironolactone and 8% the combination hydralazine/isosorbide-dinitrate. 71,7% were using enalapril, losartan or ARNi above 50% of GDMT target doses; 81,2% were using beta-blockers and 100% were using spironolactone. Only 21,2% were prescribed GDMT target doses of enalapril, losartan or ARNi and 52,3% of beta-blockers. 98,5% of spironolactone prescriptions reached GDMT target doses.</p><p><strong>Conclusions: </strong>We found high frequencies of prescription of GDMT for HFrEF, considering the therapeutic goals recommended by cardiology guidelines, but, prescription of target doses were low in ACEi, ARB or ARNi and beta-blockers.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 3","pages":"e2023315"},"PeriodicalIF":1.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practice of oxygen administration in patients hospitalized in internal medicine wards and intensive care units: A single-center prospective, observational study. 内科病房和重症监护病房住院患者给氧的实践:一项单中心前瞻性观察性研究
IF 1.3 4区 医学
Sao Paulo Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.1590/1516-3180.2024.0323.29012025
Saliha Bozkurt Esengul, Arzu Topeli, Burcin Halacli
{"title":"Practice of oxygen administration in patients hospitalized in internal medicine wards and intensive care units: A single-center prospective, observational study.","authors":"Saliha Bozkurt Esengul, Arzu Topeli, Burcin Halacli","doi":"10.1590/1516-3180.2024.0323.29012025","DOIUrl":"https://doi.org/10.1590/1516-3180.2024.0323.29012025","url":null,"abstract":"<p><strong>Background: </strong>Oxygen is widely used to treat hypoxemia.</p><p><strong>Objective: </strong>To determine the frequency of inappropriate oxygen administration in patients admitted to Internal Medicine (IM) wards and intensive care units (ICU).</p><p><strong>Design and setting: </strong>Single-center prospective, observational study in a tertiary university hospital in Ankara, Türkiye.</p><p><strong>Methods: </strong>Patients who were hospitalized in the IM wards and ICU and were receiving oxygen were recruited. Every 6 hours, the oxygenation parameters were noted, and the averages over the first 24 hours of oxygen usage were recorded. Inappropriate usage was defined as oxygen flow rates > 6 L/min in the nasal cannula and < 5 L/min and > 10 L/min in the simple face mask, application of the simple face mask in chronic obstructive lung disease (COPD) exacerbation, SpO2 > 98% in general, or SpO2 > 92% in COPD exacerbation.</p><p><strong>Results: </strong>Of the 397 patients, 20% in the IM wards and 50% of 124 in the ICU received oxygen. The oxygen method used was nasal cannula in 51%, simple face mask in 21%, and high-flow nasal cannula in 4% of the patients. Among the simple face mask applications, 46% were < 5 L/min and 5% were > 10 L/min. Among the 62% of patients with COPD exacerbations, the SpO2 was > 92%.</p><p><strong>Conclusion: </strong>The frequency of oxygen use was 20% among patients hospitalized in IM wards and 50% among patients in the ICU. Almost half of the simple face mask applications were inappropriate.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 3","pages":"e2024323"},"PeriodicalIF":1.3,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Latin American Integration Route and infectious diseases. 拉丁美洲一体化路线和传染病。
IF 1.3 4区 医学
Sao Paulo Medical Journal Pub Date : 2025-04-28 eCollection Date: 2025-01-01 DOI: 10.1590/1516-3180.2024.0049.R1.09092024
Inara Pereira da Cunha, Sandra Maria do Valle Leone de Oliveira, James Venturini, Ruberval Franco Maciel, Antonio Jose Grande
{"title":"The Latin American Integration Route and infectious diseases.","authors":"Inara Pereira da Cunha, Sandra Maria do Valle Leone de Oliveira, James Venturini, Ruberval Franco Maciel, Antonio Jose Grande","doi":"10.1590/1516-3180.2024.0049.R1.09092024","DOIUrl":"https://doi.org/10.1590/1516-3180.2024.0049.R1.09092024","url":null,"abstract":"","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2024049"},"PeriodicalIF":1.3,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frequency of scapular dyskinesis and its relationship with disease parameters in patients with ankylosing spondylitis: a cross-sectional study. 强直性脊柱炎患者肩胛骨运动障碍的频率及其与疾病参数的关系:一项横断面研究
IF 1.3 4区 医学
Sao Paulo Medical Journal Pub Date : 2025-04-28 eCollection Date: 2025-01-01 DOI: 10.1590/1516-3180.2024.0136.R1.13082024
Sertaç Ketenci, Bora Uzuner, Dilek Durmuş, Deniz Şahinkaya, Muharrem Yüksel, Ahmet Kıvanç Cengiz
{"title":"Frequency of scapular dyskinesis and its relationship with disease parameters in patients with ankylosing spondylitis: a cross-sectional study.","authors":"Sertaç Ketenci, Bora Uzuner, Dilek Durmuş, Deniz Şahinkaya, Muharrem Yüksel, Ahmet Kıvanç Cengiz","doi":"10.1590/1516-3180.2024.0136.R1.13082024","DOIUrl":"https://doi.org/10.1590/1516-3180.2024.0136.R1.13082024","url":null,"abstract":"<p><strong>Background: </strong>Scapular dyskinesis (SD) is a condition associated with impaired scapular movement caused by cervical, shoulder, and postural abnormalities.</p><p><strong>Objective: </strong>The aim of this study was to determine the frequency of SD in patients with ankylosing spondylitis (AS).</p><p><strong>Design and setting: </strong>A cross-sectional study was conducted at Ondokuz Mayıs University, Samsun, Turkey.</p><p><strong>Methods: </strong>One hundred patients with AS but without shoulder involvement (74 males and 26 females) and 50 healthy controls (35 males and 15 females) were included in the study. The patients were divided into two groups: patients with and without SD. SD was assessed using the Scapular Dyskinesis Test and Lateral Scapular Slide Test. Disease activity, spinal mobility, and chest expansion were also measured. The severity of enthesitis was evaluated using the Spondyloarthritis Research Consortium of Canada index.</p><p><strong>Results: </strong>There were significant differences between the two groups of patients with AS, those with SD, and those without SD in terms of age, chest expansion, and the Bath Ankylosing Spondylitis Metrology Index (BASMI) scores (P < 0.05). The groups differed significantly in terms of hip, thoracic, and lumbar involvement (P < 0.05). The BASMI score was a significant variable affecting SD (P < 0.05). No cases of SD were observed in the control group.</p><p><strong>Conclusion: </strong>While there were no significant differences in disease activity and enthesitis scores between patients with and without SD, differences were detected in mobility parameters. Since shoulder examinations of the patients were normal, it can be inferred that SD occurred because of the involvement of the scapulothoracic joints and thoracic spine.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2024136"},"PeriodicalIF":1.3,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The burden of healthcare-associated infections in Brazil: multi-hospital point prevalence using a matched case-control study. 巴西卫生保健相关感染的负担:采用匹配病例对照研究的多医院点流行率
IF 1.3 4区 医学
Sao Paulo Medical Journal Pub Date : 2025-04-28 eCollection Date: 2025-01-01 DOI: 10.1590/1516-3180.2023.0307.R1.03072024
Luiz Gustavo Machado, Daiane Silva Resende, Paola Amaral de Campos, Iara Rossi, Melina Lorraine Ferreira, Iolanda Alves Braga, Caio Augusto Martins Aires, Maria Tereza Freitas Tenório, Paulo Pinto Gontijo-Filho, Sabrina Royer, Rosineide Marques Ribas
{"title":"The burden of healthcare-associated infections in Brazil: multi-hospital point prevalence using a matched case-control study.","authors":"Luiz Gustavo Machado, Daiane Silva Resende, Paola Amaral de Campos, Iara Rossi, Melina Lorraine Ferreira, Iolanda Alves Braga, Caio Augusto Martins Aires, Maria Tereza Freitas Tenório, Paulo Pinto Gontijo-Filho, Sabrina Royer, Rosineide Marques Ribas","doi":"10.1590/1516-3180.2023.0307.R1.03072024","DOIUrl":"https://doi.org/10.1590/1516-3180.2023.0307.R1.03072024","url":null,"abstract":"<p><strong>Background: </strong>Healthcare-associated infections (HAIs) have a significant impact on patient care worldwide and have serious implications for the Brazilian healthcare system.</p><p><strong>Objectives: </strong>This study aimed to describe the trends in HAIs in adult intensive care units (ICUs) using data from a national point-prevalence survey.</p><p><strong>Design and setting: </strong>A point-prevalence study was conducted in 2019 across adult intensive ICUs in large acute care hospitals in Brazil.</p><p><strong>Methods: </strong>A matched case-control study was performed to assess the risk factors associated with the development of infection.</p><p><strong>Results: </strong>A total of 386 patients from 15 hospitals were studied, of whom 102 (26.4%; 102/386) were infected, and 76.5% had at least one ICU-acquired infection. In clinical-surgical ICUs (CSU), the prevalence of infections acquired in the unit was 77.9%, whereas in Coronary ICUs (COU), it was 68.7%. There was a predominance of pneumonia (51.0%), mainly caused by Gram-negative non-fermenters, and bloodstream infections (34.4%), predominantly caused by coagulase-negative Staphylococcus (CoNS). In the risk factor analysis, cancer and general antimicrobial use were independently associated.</p><p><strong>Conclusion: </strong>This study found a high burden of HAIs in adult ICUs in Brazil, mainly associated with the high use of antibiotics for infections and a worse prognosis.</p>","PeriodicalId":49574,"journal":{"name":"Sao Paulo Medical Journal","volume":"143 2","pages":"e2023307"},"PeriodicalIF":1.3,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12037148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144019657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cluster of factors related to metabolic changes in older individuals: a cross-sectional study. 与老年人代谢变化相关的一组因素:一项横断面研究。
IF 1.3 4区 医学
Sao Paulo Medical Journal Pub Date : 2025-04-28 eCollection Date: 2025-01-01 DOI: 10.1590/1516.3180.2023.0283.R1.30082024
Clarice Alves Dos Santos, Mariana Alves Dos Santos, Manuela Alves Dos Santos, Milena Fernandez Dias, Lélia Renata Carneiro Vasconcelos, Saulo Vasconcelos Rocha
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