L. Carriero, E. Pennese, P. Salutari, L. Schiattone, G. Ricciuti, F. Colasante, G. De Luca, G. Albanese, F. Restuccia, F. Sborgia, R. Giancola, M. Di Ianni
{"title":"CAR-T THERAPY: EXPERIENCE OF THE PESCARA CENTRE","authors":"L. Carriero, E. Pennese, P. Salutari, L. Schiattone, G. Ricciuti, F. Colasante, G. De Luca, G. Albanese, F. Restuccia, F. Sborgia, R. Giancola, M. Di Ianni","doi":"10.1016/j.transci.2025.104351","DOIUrl":"10.1016/j.transci.2025.104351","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104351"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of online education on cardiovascular intensive care nurses’ self-efficacy in blood transfusion: A randomized controlled trial conducted in Turkey","authors":"Ahmet Songül , Arzu Bahar","doi":"10.1016/j.transci.2025.104306","DOIUrl":"10.1016/j.transci.2025.104306","url":null,"abstract":"<div><h3>Objective</h3><div>Safe transfusion of blood and blood products is a critical and complex process in cardiovascular surgical intensive care units. This study aimed to determine nurses’ self-efficacy in safe blood transfusion and to examine the effect of a structured online training program.</div></div><div><h3>Method</h3><div>This randomized controlled study included 90 nurses working in a cardiovascular surgical intensive care unit of a training and research hospital. The intervention group (n = 45) received a 40-minute theoretical and practical online training on safe blood transfusion, while the control group (n = 45) received no training. Data were collected using a Personal Information Form and the Self-Efficacy Scale for Safe Blood and Blood Product Transfusion for Nurses. Analyses were performed with independent-samples t-tests and one-way ANOVA, with a significance level of p < 0.05.</div></div><div><h3>Results</h3><div>The post-test mean score of the intervention group (215.22 ± 10.17) was significantly higher than that of the control group (197.11 ± 24.47) (p < 0.05). All sub-dimensions—knowledge, procedural skills, and transfusion safety confidence—showed significant improvement in the intervention group. Nurses with higher education levels and younger age demonstrated greater improvements in self-efficacy scores.</div></div><div><h3>Discussion</h3><div>The structured online training was effective in increasing nurses’ self-efficacy for safe transfusion practices. Demographic factors influenced the learning outcomes.</div></div><div><h3>Conclusion</h3><div>Structured online training programs improve the knowledge, skills, and confidence of cardiovascular intensive care nurses. It is recommended that such programs be conducted regularly and tailored to demographic differences.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104306"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145884458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jingwei Zhang , Yujie Kong , Siwei Liu , Liqi Lu , Li Tian
{"title":"Association between platelet transfusion units and platelet transfusion refractoriness in patients with hematological disease: A cohort study in China","authors":"Jingwei Zhang , Yujie Kong , Siwei Liu , Liqi Lu , Li Tian","doi":"10.1016/j.transci.2025.104368","DOIUrl":"10.1016/j.transci.2025.104368","url":null,"abstract":"<div><h3>Purpose</h3><div>Patients with hematologic diseases frequently receive platelet transfusions and exhibit a higher incidence of platelet transfusion refractoriness (PTR). This study assessed whether platelet transfusion units are a risk factor for PTR.</div></div><div><h3>Methods</h3><div>We enrolled 598 patients from the Hematology Department of Chengdu Second People's Hospital (Feb 2020-Feb 2023). Based on CCI values, patients were categorized into PTR (n = 207) and non-PTR (n = 391) groups. The relationship between platelet transfusion units and PTR risk was analyzed using logistic regression, with adjustments for confounders.</div></div><div><h3>Results</h3><div>The PTR incidence was 34.61 %. Platelet transfusion units were significantly associated with increased PTR risk (OR=1.93, 95 % CI 1.67–2.24, p < 0.001); after adjusting for age, sex, infection, body mass index, disease classification, red blood cell transfusion units, and routine blood test results, this correlation increased higher (OR=2.35, 95 % CI 1.89–2.91, p < 0.001). The fitting curve between the platelet transfusion units and risk of PTR show a positive linear relationship(p = 0.472) Furthermore, when dividing platelet transfusion units into < 3 Units and ≥ 3 Units, patients receiving ≥ 3 Units had a significantly higher risk of PTR (OR=6.17, 95 % CI 4.24–8.97, p < 0.001) compared to those receiving < 3 Units; similarly, after adjusting for covariates, the risk of PTR in patients receiving ≥ 3 Units was still higher (OR=7.38, 95 % CI 4.29–12.69, p < 0.001). After propensity score matching, the risk remained robust (OR=4.59, 95 % CI 2.77–7.61, p < 0.001) across various model corrections.</div></div><div><h3>Conclusion</h3><div>Platelet transfusion units independently correlate with PTR incidence, suggesting the need for careful assessment and reduction of unnecessary transfusions.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104368"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Battista, C. Citarella, M. Colonna, R. Frappampina, R. Galasso, M. Giannoccaro, C. Lippolis, R. Procacci, A. Tullo, A. Ostuni
{"title":"RETROSPECTIVE EVALUATION OF TWO CELL SEPARATORS FOR COLLECTION OF AUTOLOGOUS AND ALLOGENEIC PERIPHERAL HSCS.","authors":"C. Battista, C. Citarella, M. Colonna, R. Frappampina, R. Galasso, M. Giannoccaro, C. Lippolis, R. Procacci, A. Tullo, A. Ostuni","doi":"10.1016/j.transci.2025.104347","DOIUrl":"10.1016/j.transci.2025.104347","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104347"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Putzulu , F. Fatone , G. Massini , P. Chiusolo , S. Giammarco , E. Metafuni , M.A. Limongiello , N. Piccirillo
{"title":"PERFORMANCE EVALUATION OF THE FRESENIUS AMICUS BLUE EXTRACORPOREAL PHOTOPHERESIS SYSTEM IN THE TREATMENT OF PATIENTS AFFECTED BY GVHD.","authors":"R. Putzulu , F. Fatone , G. Massini , P. Chiusolo , S. Giammarco , E. Metafuni , M.A. Limongiello , N. Piccirillo","doi":"10.1016/j.transci.2025.104343","DOIUrl":"10.1016/j.transci.2025.104343","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104343"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Fedele , L. Di Noto , R. Saldamarco , G. Sapienza , C. Spinelli , N. Agosto , V. Ditta , R. Bono , S. Tringali , C. Rotolo , C. Patti , F. Accardi , L. Castagna
{"title":"STEM CELL COLLECTION AFTER DARATUMUMAB – BASED INDUCTION THERAPY IN MULTIPLE MYELOMA PATIENTS: SINGLE-CENTER EXPERIENCE","authors":"R. Fedele , L. Di Noto , R. Saldamarco , G. Sapienza , C. Spinelli , N. Agosto , V. Ditta , R. Bono , S. Tringali , C. Rotolo , C. Patti , F. Accardi , L. Castagna","doi":"10.1016/j.transci.2025.104333","DOIUrl":"10.1016/j.transci.2025.104333","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104333"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}