M. Prisciandaro , C. Bancone , G. Palazzo , C. Bonchi , C. Nobile , L. D'Amore , C. Gregorj , A. Marinucci , S. Vaccaro , D. Armiento , O. Annibali , M. Vacca
{"title":"PREDICTIVE ALGORITHM FOR HAEMATOPOIETIC STEM CELL COLLECTION AS A TOOL FOR INTERCONNECTION BETWEEN TRANSPLANT PROGRAM FACILITIES","authors":"M. Prisciandaro , C. Bancone , G. Palazzo , C. Bonchi , C. Nobile , L. D'Amore , C. Gregorj , A. Marinucci , S. Vaccaro , D. Armiento , O. Annibali , M. Vacca","doi":"10.1016/j.transci.2025.104332","DOIUrl":"10.1016/j.transci.2025.104332","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104332"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andre D. Luchessi , Thomas Sierocinski , Teenus P. Jayaprakash , Celina Montemayor Garcia
{"title":"Bioinformatic applications in blood group molecular typing","authors":"Andre D. Luchessi , Thomas Sierocinski , Teenus P. Jayaprakash , Celina Montemayor Garcia","doi":"10.1016/j.transci.2025.104300","DOIUrl":"10.1016/j.transci.2025.104300","url":null,"abstract":"<div><div>The application of molecular laboratory methods to predict the expression of red blood cell antigens is well established in today’s clinical transfusion practice. The advent of high-throughput molecular blood typing approaches – based on microarray, short-read, and long-read next generation sequencing platforms – has set the stage for widespread, high-resolution donor and patient typing, encompassing the entire breadth of known antigens and propelling swift discovery in this field. Realizing these benefits requires not only carefully designed and validated laboratory assays, but also robust computational and software infrastructures for processing, storing, and interpreting the large volume of generated data, which may represent a new challenge for blood collectors and transfusion centers. To support this practice transition and facilitate adoption of these technologies, we review recent literature on genomic blood typing approaches, outline IT infrastructure considerations, describe available software and analytical algorithms, and discuss the emerging role of artificial intelligence in this rapidly evolving space.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104300"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145879365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Carriero, E. Pennese, P. Salutari, L. Schiattone, G. Ricciuti, F. Colasante, G. De Luca, G. Albanese, F. Restuccia, F. Sborgia, R. Giancola, M. Di Ianni
{"title":"CAR-T THERAPY: EXPERIENCE OF THE PESCARA CENTRE","authors":"L. Carriero, E. Pennese, P. Salutari, L. Schiattone, G. Ricciuti, F. Colasante, G. De Luca, G. Albanese, F. Restuccia, F. Sborgia, R. Giancola, M. Di Ianni","doi":"10.1016/j.transci.2025.104351","DOIUrl":"10.1016/j.transci.2025.104351","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104351"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of online education on cardiovascular intensive care nurses’ self-efficacy in blood transfusion: A randomized controlled trial conducted in Turkey","authors":"Ahmet Songül , Arzu Bahar","doi":"10.1016/j.transci.2025.104306","DOIUrl":"10.1016/j.transci.2025.104306","url":null,"abstract":"<div><h3>Objective</h3><div>Safe transfusion of blood and blood products is a critical and complex process in cardiovascular surgical intensive care units. This study aimed to determine nurses’ self-efficacy in safe blood transfusion and to examine the effect of a structured online training program.</div></div><div><h3>Method</h3><div>This randomized controlled study included 90 nurses working in a cardiovascular surgical intensive care unit of a training and research hospital. The intervention group (n = 45) received a 40-minute theoretical and practical online training on safe blood transfusion, while the control group (n = 45) received no training. Data were collected using a Personal Information Form and the Self-Efficacy Scale for Safe Blood and Blood Product Transfusion for Nurses. Analyses were performed with independent-samples t-tests and one-way ANOVA, with a significance level of p < 0.05.</div></div><div><h3>Results</h3><div>The post-test mean score of the intervention group (215.22 ± 10.17) was significantly higher than that of the control group (197.11 ± 24.47) (p < 0.05). All sub-dimensions—knowledge, procedural skills, and transfusion safety confidence—showed significant improvement in the intervention group. Nurses with higher education levels and younger age demonstrated greater improvements in self-efficacy scores.</div></div><div><h3>Discussion</h3><div>The structured online training was effective in increasing nurses’ self-efficacy for safe transfusion practices. Demographic factors influenced the learning outcomes.</div></div><div><h3>Conclusion</h3><div>Structured online training programs improve the knowledge, skills, and confidence of cardiovascular intensive care nurses. It is recommended that such programs be conducted regularly and tailored to demographic differences.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104306"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145884458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jingwei Zhang , Yujie Kong , Siwei Liu , Liqi Lu , Li Tian
{"title":"Association between platelet transfusion units and platelet transfusion refractoriness in patients with hematological disease: A cohort study in China","authors":"Jingwei Zhang , Yujie Kong , Siwei Liu , Liqi Lu , Li Tian","doi":"10.1016/j.transci.2025.104368","DOIUrl":"10.1016/j.transci.2025.104368","url":null,"abstract":"<div><h3>Purpose</h3><div>Patients with hematologic diseases frequently receive platelet transfusions and exhibit a higher incidence of platelet transfusion refractoriness (PTR). This study assessed whether platelet transfusion units are a risk factor for PTR.</div></div><div><h3>Methods</h3><div>We enrolled 598 patients from the Hematology Department of Chengdu Second People's Hospital (Feb 2020-Feb 2023). Based on CCI values, patients were categorized into PTR (n = 207) and non-PTR (n = 391) groups. The relationship between platelet transfusion units and PTR risk was analyzed using logistic regression, with adjustments for confounders.</div></div><div><h3>Results</h3><div>The PTR incidence was 34.61 %. Platelet transfusion units were significantly associated with increased PTR risk (OR=1.93, 95 % CI 1.67–2.24, p < 0.001); after adjusting for age, sex, infection, body mass index, disease classification, red blood cell transfusion units, and routine blood test results, this correlation increased higher (OR=2.35, 95 % CI 1.89–2.91, p < 0.001). The fitting curve between the platelet transfusion units and risk of PTR show a positive linear relationship(p = 0.472) Furthermore, when dividing platelet transfusion units into < 3 Units and ≥ 3 Units, patients receiving ≥ 3 Units had a significantly higher risk of PTR (OR=6.17, 95 % CI 4.24–8.97, p < 0.001) compared to those receiving < 3 Units; similarly, after adjusting for covariates, the risk of PTR in patients receiving ≥ 3 Units was still higher (OR=7.38, 95 % CI 4.29–12.69, p < 0.001). After propensity score matching, the risk remained robust (OR=4.59, 95 % CI 2.77–7.61, p < 0.001) across various model corrections.</div></div><div><h3>Conclusion</h3><div>Platelet transfusion units independently correlate with PTR incidence, suggesting the need for careful assessment and reduction of unnecessary transfusions.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104368"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Battista, C. Citarella, M. Colonna, R. Frappampina, R. Galasso, M. Giannoccaro, C. Lippolis, R. Procacci, A. Tullo, A. Ostuni
{"title":"RETROSPECTIVE EVALUATION OF TWO CELL SEPARATORS FOR COLLECTION OF AUTOLOGOUS AND ALLOGENEIC PERIPHERAL HSCS.","authors":"C. Battista, C. Citarella, M. Colonna, R. Frappampina, R. Galasso, M. Giannoccaro, C. Lippolis, R. Procacci, A. Tullo, A. Ostuni","doi":"10.1016/j.transci.2025.104347","DOIUrl":"10.1016/j.transci.2025.104347","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104347"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}