{"title":"Biography of the guest editor for this issue's theme papers on \"Green\" methodology in blood purification techniques","authors":"Ioannis Griveas","doi":"10.1016/j.transci.2025.104225","DOIUrl":"10.1016/j.transci.2025.104225","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 5","pages":"Article 104225"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A place for plasmapheresis","authors":"Lise Sofie H. Nissen-Meyer","doi":"10.1016/j.transci.2025.104234","DOIUrl":"10.1016/j.transci.2025.104234","url":null,"abstract":"<div><div>The increased need for source plasma in the production of plasma-derived medical products has received attention and elicited diverse actions in Europe lately. The discrepancy between production and utilization poses ethical as well as medical questions to be discussed in the international community. The contribution of non-remunerated voluntary donors should be encouraged, and several nations have addressed the problem in national plasma strategy documents. Independent of this, blood centers have increased their plasmapheresis activity in efforts to increase plasma donation and retain valuable donors, in parallel with decreased use of cellular blood products. In Oslo Blood Center we have encouraged our whole blood donors to also donate plasma, by which we keep them active and prepared for whole blood donation if an urgent situation rises. In this commentary I describe the change of mind set necessary to increase the number of plasmaphereses within the current frameworks.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 5","pages":"Article 104234"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144781725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Citrate, a green alternative to heparin","authors":"Ioannis Griveas","doi":"10.1016/j.transci.2025.104229","DOIUrl":"10.1016/j.transci.2025.104229","url":null,"abstract":"<div><div>An alternative to systemic heparin anticoagulation for HD is citrate dialysate (CD) which contains a small amount of citric acid. The nephrology community demands an environmentally sustainable kidney care and among others, heparin is a threat to planetary health. Citrate is the green alternative to heparin in HD and it is most likely better for the internal enviromment since it simultaneously provokes increased hemoglobin with a fixed dose of erythropoietin and reduced iron administration.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 5","pages":"Article 104229"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144773185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"\"Green\" methodology: An overview and basic principles","authors":"Ioannis Griveas","doi":"10.1016/j.transci.2025.104226","DOIUrl":"10.1016/j.transci.2025.104226","url":null,"abstract":"<div><div>Annual carbon emissions for dialysis treatments in different regions range from 3818–10,200 kgrs for haemodialysis (HD) and 1450–4503 CO2 eq/pt/year which correlates to the carbon foot print of production of 2727–7285 lits or driving a car for 27,291–72,909 km. In order to communicate as a scientific team and to understand each other we have to use terms that actually describe our “problem”. There is also need of a full environmental assessment concerning blood purification technology.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 5","pages":"Article 104226"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144779646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ascorbic acid in dialysates, a novel defensive mechanism","authors":"Ioannis Griveas","doi":"10.1016/j.transci.2025.104230","DOIUrl":"10.1016/j.transci.2025.104230","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 5","pages":"Article 104230"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144781723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The ecological footprint of therapeutic plasmapheresis methods","authors":"Paraskevi Tseke , Petros Tsekes , Ioannis Griveas","doi":"10.1016/j.transci.2025.104227","DOIUrl":"10.1016/j.transci.2025.104227","url":null,"abstract":"<div><div>Global warming is one of the most pressing issues of our century with negative impacts on human health. Healthcare services are vital for human well-being. At the same time healthcare systems have been recognized as major contributors to the climate crisis. As health and health equity are the ultimate goals for humanity, evaluation of the ecological footprint in different areas of medical practice enhances knowledge and information needed to mitigate negative health effects of climate change. Although numerous studies have clearly demonstrated the ecological effects of hemodialysis there is no data regarding the ecologic impact of apheresis procedures. We aimed to summarize some of the available information regarding the key sources of apheresis carbon emissions hoping to make a first step towards pragmatic assessments.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 5","pages":"Article 104227"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144750514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pratham D. Patel , Ethan A. Simpson , Jason P. Acker
{"title":"Irradiation and beyond: Mitigating TA-GVHD in transfusion","authors":"Pratham D. Patel , Ethan A. Simpson , Jason P. Acker","doi":"10.1016/j.transci.2025.104237","DOIUrl":"10.1016/j.transci.2025.104237","url":null,"abstract":"<div><div>Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare but often fatal complication of allogeneic transfusion, caused by the activation and expansion of donor T lymphocytes in susceptible recipients. Prevention focuses on reducing these immune cells through leukoreduction and irradiation. While leukoreduction of blood components decreases white blood cell content and improves overall transfusion safety, it does not fully prevent TA-GVHD, as viable T cells may persist. Irradiation using gamma or X-ray methods remain the most effective strategy, inactivating donor T cells by inducing DNA damage and suppressing proliferation. However, it also compromises red blood cell quality by increasing hemolysis, oxidative injury, membrane damage, extracellular potassium, and reducing storage duration. As an alternative, hypothermic storage of leukoreduced red blood cells is gaining attention. Evidence suggests that extending storage beyond 21 days significantly reduces T cell viability and proliferation without compromising red blood cell integrity. Further research is needed to directly compare the efficacy of hypothermic storage to irradiation.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 5","pages":"Article 104237"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144750508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New WAA member: The Spanish Apheresis Group 2","authors":"Joan Cid","doi":"10.1016/j.transci.2025.104224","DOIUrl":"10.1016/j.transci.2025.104224","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 5","pages":"Article 104224"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144781722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial Commentary - Expert insights on advancing innovations in modernised blood components therapy and a shift from conventional storage using hypoxic/hypothermic storage of red blood cells, in select clinical scenarios, to improve patient-centred transfusion care","authors":"Jerard Seghatchian","doi":"10.1016/j.transci.2025.104233","DOIUrl":"10.1016/j.transci.2025.104233","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 5","pages":"Article 104233"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144763969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Norway: Blood donors and the innovative research and development on some unmet challenges","authors":"Tor Audun Hervig","doi":"10.1016/j.transci.2025.104236","DOIUrl":"10.1016/j.transci.2025.104236","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"64 5","pages":"Article 104236"},"PeriodicalIF":1.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144763968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}