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DESENSITIZATION IN KIDNEY TRANSPLANT PATIENTS PRESENTING ANTIBODY-MEDIATED REJECTION, THROUGH THERAPEUTIC PLASMA EXCHANGE 通过治疗性血浆交换，出现抗体介导排斥反应的肾移植患者脱敏
IF 1.2 4区 医学
Transfusion and Apheresis Science Pub Date : 2026-02-01 Epub Date: 2026-01-30 DOI: 10.1016/j.transci.2025.104327
A. Rughetti , V. Del Greco , O. Staltari , C. Cervelli , O. Valdez , M.G. Tupone , R. Azzarone , A. Panarese , F. Pisani , F. Papola
{"title":"DESENSITIZATION IN KIDNEY TRANSPLANT PATIENTS PRESENTING ANTIBODY-MEDIATED REJECTION, THROUGH THERAPEUTIC PLASMA EXCHANGE","authors":"A. Rughetti , V. Del Greco , O. Staltari , C. Cervelli , O. Valdez , M.G. Tupone , R. Azzarone , A. Panarese , F. Pisani , F. Papola","doi":"10.1016/j.transci.2025.104327","DOIUrl":"10.1016/j.transci.2025.104327","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104327"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THROMBOTIC MICROANGIOPATHY (TMA): THE HEMATOLOGICAL PERSPECTIVE 血栓性微血管病（tma）：血液学的观点
IF 1.2 4区 医学
Transfusion and Apheresis Science Pub Date : 2026-02-01 Epub Date: 2026-01-30 DOI: 10.1016/j.transci.2025.104366
F. Schieppati , A. Falanga
{"title":"THROMBOTIC MICROANGIOPATHY (TMA): THE HEMATOLOGICAL PERSPECTIVE","authors":"F. Schieppati , A. Falanga","doi":"10.1016/j.transci.2025.104366","DOIUrl":"10.1016/j.transci.2025.104366","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104366"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IMPACT OF CAPLACIZUMAB IN THE MANAGEMENT OF THROMBOTIC THROMBOCYTOPENIC PURPURA 卡普拉珠单抗在治疗血栓性血小板减少性紫癜中的作用
IF 1.2 4区 医学
Transfusion and Apheresis Science Pub Date : 2026-02-01 Epub Date: 2026-01-30 DOI: 10.1016/j.transci.2025.104309
M. Napolitano , M. Mattana , R. Tomasello R. , S. Siragusa , M. Ciaccio , E. Scirè
{"title":"IMPACT OF CAPLACIZUMAB IN THE MANAGEMENT OF THROMBOTIC THROMBOCYTOPENIC PURPURA","authors":"M. Napolitano , M. Mattana , R. Tomasello R. , S. Siragusa , M. Ciaccio , E. Scirè","doi":"10.1016/j.transci.2025.104309","DOIUrl":"10.1016/j.transci.2025.104309","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104309"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A CASE OF IMMUNE THROMBOCYTOPENIA WITH THROMBOSIS (VITT-LIKE) INDUCED BY ADENOVIRUS INFECTION TREATED WITH PLASMA EXCHANGE 血浆置换治疗腺病毒感染引起的免疫性血小板减少伴血栓形成1例
IF 1.2 4区 医学
Transfusion and Apheresis Science Pub Date : 2026-02-01 Epub Date: 2026-01-30 DOI: 10.1016/j.transci.2025.104312
Colpo A , Sartori M.T. , Hoxha A. , Munari M. , Campello E. , Simioni P. , D'Amore F. , Leahu A.I. , Pavanello F. , Tison T.
{"title":"A CASE OF IMMUNE THROMBOCYTOPENIA WITH THROMBOSIS (VITT-LIKE) INDUCED BY ADENOVIRUS INFECTION TREATED WITH PLASMA EXCHANGE","authors":"Colpo A , Sartori M.T. , Hoxha A. , Munari M. , Campello E. , Simioni P. , D'Amore F. , Leahu A.I. , Pavanello F. , Tison T.","doi":"10.1016/j.transci.2025.104312","DOIUrl":"10.1016/j.transci.2025.104312","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104312"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146073718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Granulocyte apheresis in donors: A comparative study of spectra optia and cobe spectra apheresis systems 供体粒细胞单采：光谱光学和cobe光谱单采系统的比较研究
IF 1.2 4区 医学
Transfusion and Apheresis Science Pub Date : 2026-02-01 Epub Date: 2025-11-25 DOI: 10.1016/j.transci.2025.104284
Linda John , Arif Vaheedu A.A , Pavithra Ramanadhan , Mohandoss Murugesan , Veena Shenoy
{"title":"Granulocyte apheresis in donors: A comparative study of spectra optia and cobe spectra apheresis systems","authors":"Linda John ,&nbsp;Arif Vaheedu A.A ,&nbsp;Pavithra Ramanadhan ,&nbsp;Mohandoss Murugesan ,&nbsp;Veena Shenoy","doi":"10.1016/j.transci.2025.104284","DOIUrl":"10.1016/j.transci.2025.104284","url":null,"abstract":"<div><h3>Background</h3><div>Granulocyte transfusion (GTX) is a significant adjunctive treatment for patients with refractory infections and severe neutropenia. High-dose granulocyte concentrates are best collected by optimized mobilization and apheresis techniques. Among the most popular platforms, COBE Spectra and Spectra Optia differ in terms of technology and operational characteristics; however, comparative data from Indian settings are limited.</div></div><div><h3>Methods</h3><div>This retrospective study evaluated 316 granulocyte apheresis sessions conducted between 2013 and 2022 in a tertiary care centre in Kerala, India. G-CSF (450 μg) and dexamethasone (8 mg) were used to mobilize the donors. COBE Spectra (n = 112) or Spectra Optia (n = 204) were used to conduct the apheresis. Demographics, pre-procedural haematological parameters, granulocyte product characteristics, and procedural variables, such as the collection efficiency (CE), were compared.</div></div><div><h3>Results</h3><div>Donor demographics were comparable between groups. COBE Spectra yielded significantly higher granulocyte counts (49.7 ± 20.6 vs. 36.2 ± 19.2 × 10⁹; p &lt; 0.001), but required larger volumes of processed blood (9359 ± 1588 vs. 5740 ± 475 ml; p &lt; 0.001) and greater anticoagulant usage. Spectra Optia demonstrated a greater collection efficiency (24.9 ± 14.9 % vs. 19.3 ± 6.7 %; p &lt; 0.001), albeit with lower yields and product volumes. Spectra Optia had less contamination of RBC and platelets. Procedure duration was comparable between systems (p = 0.670).</div></div><div><h3>Conclusion</h3><div>The two systems demonstrated clinically acceptable granulocyte yields; however, the Spectra Optia had greater collection efficiency with less red cell contamination, suggesting it as a preferred choice.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104284"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145624877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COUNSELING IN APHERESIS FIELD 血液分离领域的咨询
IF 1.2 4区 医学
Transfusion and Apheresis Science Pub Date : 2026-02-01 Epub Date: 2026-01-30 DOI: 10.1016/j.transci.2025.104311
Cipriani R , Reali P , Frediani P , Conte A , Manzardo C , Bernabò T , Basso L , Spurio S , Spalluto M , Ponte E , Pierelli L
{"title":"COUNSELING IN APHERESIS FIELD","authors":"Cipriani R ,&nbsp;Reali P ,&nbsp;Frediani P ,&nbsp;Conte A ,&nbsp;Manzardo C ,&nbsp;Bernabò T ,&nbsp;Basso L ,&nbsp;Spurio S ,&nbsp;Spalluto M ,&nbsp;Ponte E ,&nbsp;Pierelli L","doi":"10.1016/j.transci.2025.104311","DOIUrl":"10.1016/j.transci.2025.104311","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104311"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146076923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP): PLASMA EXCHANGE (PEX) AND HOSPITALIZATION IN PRE- AND POST-CAPLACIZUMAB ERA AT PESCARA HOSPITAL 佩斯卡拉医院血栓性血小板减少性紫癜（ttp）：血浆置换（pex）和卡普拉珠单抗前后住院治疗
IF 1.2 4区 医学
Transfusion and Apheresis Science Pub Date : 2026-02-01 Epub Date: 2026-01-30 DOI: 10.1016/j.transci.2025.104316
G. Albanese , P. Salutari , F. Colasante , G. De Luca , R. Giancola , O. Iuliani , C. Passeri , F. Restuccia , L. Carriero , M. Di Ianni , P. Accorsi
{"title":"THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP): PLASMA EXCHANGE (PEX) AND HOSPITALIZATION IN PRE- AND POST-CAPLACIZUMAB ERA AT PESCARA HOSPITAL","authors":"G. Albanese ,&nbsp;P. Salutari ,&nbsp;F. Colasante ,&nbsp;G. De Luca ,&nbsp;R. Giancola ,&nbsp;O. Iuliani ,&nbsp;C. Passeri ,&nbsp;F. Restuccia ,&nbsp;L. Carriero ,&nbsp;M. Di Ianni ,&nbsp;P. Accorsi","doi":"10.1016/j.transci.2025.104316","DOIUrl":"10.1016/j.transci.2025.104316","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104316"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146077326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial commentary – Reflections on integrating some rapidly evolving essential developments into blood transfusion practice, with fresh eyes on innovation and operational excellence: Current status and future opportunities 编辑评论-关于将一些快速发展的基本发展纳入输血实践的思考，以新的眼光看待创新和卓越运营：现状和未来机遇。
IF 1.2 4区 医学
Transfusion and Apheresis Science Pub Date : 2026-02-01 Epub Date: 2025-12-20 DOI: 10.1016/j.transci.2025.104302
Jerard Seghatchian
{"title":"Editorial commentary – Reflections on integrating some rapidly evolving essential developments into blood transfusion practice, with fresh eyes on innovation and operational excellence: Current status and future opportunities","authors":"Jerard Seghatchian","doi":"10.1016/j.transci.2025.104302","DOIUrl":"10.1016/j.transci.2025.104302","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104302"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145829039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The case for universal leukoreduction of blood transfusions 输血中普遍白细胞诱导的案例。
IF 1.2 4区 医学
Transfusion and Apheresis Science Pub Date : 2026-02-01 Epub Date: 2025-12-20 DOI: 10.1016/j.transci.2025.104305
Nicholas Tong , Debra Masel , Phuong-Lan Nguyen , Akua Asante , Majed Refaai , Neil Blumberg
{"title":"The case for universal leukoreduction of blood transfusions","authors":"Nicholas Tong ,&nbsp;Debra Masel ,&nbsp;Phuong-Lan Nguyen ,&nbsp;Akua Asante ,&nbsp;Majed Refaai ,&nbsp;Neil Blumberg","doi":"10.1016/j.transci.2025.104305","DOIUrl":"10.1016/j.transci.2025.104305","url":null,"abstract":"<div><div>Leukoreduction is the process by which most donor leukocytes are removed from blood components either at the time of blood product manufacture or prior to transfusion. It has been shown to reduce the incidence of febrile nonhemolytic transfusion reactions, transfusion transmitted CMV infections, HLA alloimmunization and platelet refractoriness. Despite the reported benefits of leukoreduction, the FDA has not taken action to implement universal leukoreduction. In this review, we discuss the evidence from observational, retrospective and randomized controlled trials for and against leukoreduction. We advocate for the adoption of universal leukoreduction, which would improve patient outcomes and pay for itself.</div></div>","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104305"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145821855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A STEM CELL DONATION WITH A COVID-19 POSITIVE MATCHED UNRELATED DONOR 与COVID-19阳性匹配的非亲属捐赠者的干细胞捐赠
IF 1.2 4区 医学
Transfusion and Apheresis Science Pub Date : 2026-02-01 Epub Date: 2026-01-30 DOI: 10.1016/j.transci.2025.104330
M.M. Polisi , M. Bevini , D. Venturelli
{"title":"A STEM CELL DONATION WITH A COVID-19 POSITIVE MATCHED UNRELATED DONOR","authors":"M.M. Polisi ,&nbsp;M. Bevini ,&nbsp;D. Venturelli","doi":"10.1016/j.transci.2025.104330","DOIUrl":"10.1016/j.transci.2025.104330","url":null,"abstract":"","PeriodicalId":49422,"journal":{"name":"Transfusion and Apheresis Science","volume":"65 1","pages":"Article 104330"},"PeriodicalIF":1.2,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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