Citrate, a green alternative to heparin

IF 1.2 4区医学 Q4 HEMATOLOGY

Transfusion and Apheresis Science Pub Date : 2025-07-28 DOI:10.1016/j.transci.2025.104229

Ioannis Griveas

引用次数: 0

Abstract

An alternative to systemic heparin anticoagulation for HD is citrate dialysate (CD) which contains a small amount of citric acid. The nephrology community demands an environmentally sustainable kidney care and among others, heparin is a threat to planetary health. Citrate is the green alternative to heparin in HD and it is most likely better for the internal enviromment since it simultaneously provokes increased hemoglobin with a fixed dose of erythropoietin and reduced iron administration.

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柠檬酸盐，肝素的绿色替代品

一种替代系统性肝素抗凝治疗HD的方法是柠檬酸透析液（CD），它含有少量的柠檬酸。肾脏病学界要求环境可持续的肾脏护理，其中肝素是对地球健康的威胁。在HD中，柠檬酸盐是肝素的绿色替代品，它很可能对内环境更好，因为它在固定剂量的促红细胞生成素和减少铁的使用的同时，会引起血红蛋白的增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Transfusion and Apheresis Science 医学-血液学

CiteScore

3.60

自引率

5.30%

发文量

181

审稿时长

42 days

期刊介绍： Transfusion and Apheresis Science brings comprehensive and up-to-date information to physicians and health care professionals involved in the rapidly changing fields of transfusion medicine, hemostasis and apheresis. The journal presents original articles relating to scientific and clinical studies in the areas of immunohematology, transfusion practice, bleeding and thrombotic disorders and both therapeutic and donor apheresis including hematopoietic stem cells. Topics covered include the collection and processing of blood, compatibility testing and guidelines for the use of blood products, as well as screening for and transmission of blood-borne diseases. All areas of apheresis - therapeutic and collection - are also addressed. We would like to specifically encourage allied health professionals in this area to submit manuscripts that relate to improved patient and donor care, technical aspects and educational issues. Transfusion and Apheresis Science features a "Theme" section which includes, in each issue, a group of papers designed to review a specific topic of current importance in transfusion and hemostasis for the discussion of topical issues specific to apheresis and focuses on the operators'' viewpoint. Another section is "What''s Happening" which provides informal reporting of activities in the field. In addition, brief case reports and Letters to the Editor, as well as reviews of meetings and events of general interest, and a listing of recent patents make the journal a complete source of information for practitioners of transfusion, hemostasis and apheresis science. Immediate dissemination of important information is ensured by the commitment of Transfusion and Apheresis Science to rapid publication of both symposia and submitted papers.