European Geriatric Medicine最新文献

{"title":"Bridging the gap: improving the long-term management of very old patients in intensive care.","authors":"Hélène Vallet, Hidenori Arai, Jeremy M Jacobs","doi":"10.1007/s41999-025-01190-3","DOIUrl":"https://doi.org/10.1007/s41999-025-01190-3","url":null,"abstract":"","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144009782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dyspepsia in nonagenarian women.","authors":"Ersin Kuloglu, Ilker Sengul, Demet Sengul, Ali Muhtaroglu, Sefer Aslan, Kubilay Issever, Ahmet Cumhur Dulger","doi":"10.1007/s41999-025-01197-w","DOIUrl":"https://doi.org/10.1007/s41999-025-01197-w","url":null,"abstract":"<p><strong>Purpose: </strong>Dyspeptic complaints are common across all age groups, but limited research explores their characteristics and underlying pathologies in nonagenarians. This pioneering study aims to investigate the clinical, laboratory, and histopathological features in women nonagenarians vs. middle-aged.</p><p><strong>Methods: </strong>A cross-sectional study included 93 female nonagenarians and 90 under 65 years (control), all presenting with dyspeptic complaints to general surgery, internal medicine, and gastroenterology outpatient clinics. Both groups underwent comprehensive evaluations, including laboratory parameters, upper gastric endoscopic examinations, and histopathological assessments of gastric biopsies. Statistical analysis compared the two groups' demographic, laboratory, and histopathological findings.</p><p><strong>Results: </strong>Of the patients included in the study, 49.8% were under 65 years, and 50.2% were nonagenarians. The mean age of the control group was 54.8 years, while nonagenarians had a mean age of 92.7 years. Significant differences were observed in several laboratory biomarkers such as leukocytes, neutrophils, glucose, creatinine, sodium, potassium, albumin, alanine transaminase, C-reactive protein, etc. between the groups (p < 0.05). Nonagenarians were less infected with Helicobacter pylori, whereas they had a higher frequency of intestinal metaplasia.</p><p><strong>Conclusions: </strong>Nonagenarians group has a higher rate of intestinal metaplasia and displasia, while a lower rate of Helicobacter pylori infection in their gastric mucosal specimens. More extensive randomized controlled trials should illuminate the possible pathophysiological mechanisms for this association.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Make us a priority, rather than just a tool for work\": the drive to attract future geriatricians.","authors":"Karolina Piotrowicz, Robert Kupis, Jerzy Gąsowski","doi":"10.1007/s41999-025-01196-x","DOIUrl":"https://doi.org/10.1007/s41999-025-01196-x","url":null,"abstract":"","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical appraisal of: the effect of intravenous vitamin C administration on postoperative pain and intraoperative blood loss in older patients after intramedullary nailing of trochanteric fractures.","authors":"Muhammad Zarrar","doi":"10.1007/s41999-025-01203-1","DOIUrl":"https://doi.org/10.1007/s41999-025-01203-1","url":null,"abstract":"","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strengthening recovery: the impact of paired exercises in geriatric hip fracture rehabilitation-the PaLMe project.","authors":"Eyal Yaacobi, Shanny Gur, Adi Berliner Senderey, Ben Kapner, Tom Mushkat, Gili Golan, Smadar Pasand Van-Stee, Tova Farjun, Nissim Ohana","doi":"10.1007/s41999-025-01192-1","DOIUrl":"https://doi.org/10.1007/s41999-025-01192-1","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effectiveness of the PaLMe concept, which incorporates paired exercises into rehabilitation for old patients recovering from hip fracture surgery, and to assess the feasibility of implementing an online rehabilitation program in this population.</p><p><strong>Methods: </strong>A prospective, randomized interventional study was conducted in a hospital setting. A total of 93 participants (mean age: 80.5 years, 66% women) were enrolled and randomized into an intervention group (PaLMe, paired exercises, n = 44) or a control group (individual exercises, n = 49). The study intervention lasted for the duration of the hospital stay, with an average length of 5.6 days. In the PaLMe group, participants were paired using a custom algorithm developed to match patients based on similar clinical and demographic characteristics, fostering interaction and mutual motivation during synchronized exercises. Walking ability was measured by distance walked and level of assistance required, while self-efficacy and motivation were assessed using validated scales. Feasibility was evaluated through recruitment and retention rates, adherence to prescribed sessions, and participant feedback on usability and satisfaction. Data were analyzed using independent t-tests and qualitative feedback.</p><p><strong>Results: </strong>The PaLMe group demonstrated significantly greater improvements in walking distance, with 66% achieving ≥ 21 m at discharge compared to 43% in the control group (p < .05). Self-efficacy and motivation also improved more in the PaLMe group. Feasibility metrics indicated high program acceptability, with recruitment and retention rates of 37% and 89%, respectively. Adherence to the program was moderate, with 47% of PaLMe participants completing more than 50% of prescribed sessions. Participant feedback highlighted increased confidence, motivation, and satisfaction with the paired exercise format, despite logistical challenges such as scheduling conflicts.</p><p><strong>Conclusion: </strong>The PaLMe program significantly enhances physical and psychological recovery in senior patients after hip fracture surgery, demonstrating its potential as an effective rehabilitation strategy. Feasibility findings indicate strong acceptability but highlight logistical barriers, such as scheduling conflicts and adherence challenges, which must be addressed to optimize implementation. Further research is warranted to explore long-term outcomes and scalability across broader settings.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of falls with risk of dementia and all-cause mortality: a cohort study of Japanese older adults with a 9-year follow-up.","authors":"Xiangbin Zhong, Keyang Liu, Yao Yao, Honglin Cai, Baoqing Huang, Xiaojing Yuan, Kokoro Shirai, Katsunori Kondo, Liqi Guan, Qiqing Chen, Xinlei Wang, Yuting Li","doi":"10.1007/s41999-024-01149-w","DOIUrl":"10.1007/s41999-024-01149-w","url":null,"abstract":"<p><strong>Objective: </strong>Many risk factors affect dementia and all-cause mortality. However, whether falls are a risk factor for dementia and all-cause mortality is unclear. The study examines the association of falls with the risk of dementia and all-cause mortality, and whether dementia mediates the association of falls with all-cause mortality.</p><p><strong>Methods: </strong>Data were taken from the Japanese Gerontological Evaluation Study (JAGES) with a 9-year follow-up. Falls information was collected through a questionnaire and categorized into no falls, single and multiple falls. Dementia and all-cause mortality data were obtained from the long-term care insurance (LTCI) system. The Cox proportional hazard models were used to calculate the hazard ratios (HRs) and 95% confidence intervals (95% CIs), and causal mediation analysis (CMA) was used to assess the mediating effects of dementia.</p><p><strong>Results: </strong>A total of 52,076 participants were included in the study. Compared to participants with no falls, participants with single and multiple falls had an increased risk of dementia (single fall, HRs = 1.18, 95% CIs 1.12-1.24; multiple falls, HRs = 1.66, 95% CIs 1.56-1.77) and all-cause mortality (single fall, HRs = 1.09, 95% CIs 1.04-1.15; multiple falls, HRs = 1.34, 95% CIs 1.26-1.43), and the risk increased with the number of falls (P for trend < 0.01). In addition, dementia significantly mediated the association between falls and risk of all-cause mortality (NIE: HRs = 1.02, 95% CIs 1.00-1.04, PM = 15.0%).</p><p><strong>Conclusion: </strong>Falls are associated with the risk of dementia and all-cause mortality. Dementia has important mediating effects in the association between falls and the risk of all-cause mortality.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"645-654"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of determining gait independence using adductor pollicis muscle thickness and skeletal muscle mass index in community-dwelling older adults undergoing outpatient rehabilitation.","authors":"Taisei Ishimoto, Takehiro Fujimoto, Ken Hisamatsu, Nozomi Matsudaira, Hikaru Hayashi, Risako Hashimoto, Yoshio Toyota, Naoki Akazawa","doi":"10.1007/s41999-024-01145-0","DOIUrl":"10.1007/s41999-024-01145-0","url":null,"abstract":"<p><strong>Objective: </strong>The accuracy of determining gait independence using adductor pollicis muscle thickness (APMT) and skeletal muscle mass index (SMI) in community-dwelling older adults undergoing outpatient rehabilitation remains unclear. The purpose of this study was to compare the accuracy of determining gait independence using APMT and SMI in community-dwelling older adults undergoing outpatient rehabilitation.</p><p><strong>Methods: </strong>This study included 98 older adults (mean age: 85.2 years). Participants received outpatient rehabilitation one to three times a week. The main outcomes were gait independence (functional independence measure gait score: 6 or 7), skeletal muscle mass index (SMI), and APMT. Receiver operating characteristic (ROC) curves of APMT and SMI for gait independence were created, and cut-off values were calculated using the Youden index. Additionally, the area under the curve (AUC) s of the APMT model and the SMI model were compared using the Delong test.</p><p><strong>Results: </strong>Among the 98 participants (male; 19, female; 79), 53 (54.1%) were in the gait independent group. The cut-off value of APMT calculated from the ROC curve was 13 mm; the sensitivity and specificity were 67.9% and 86.7%, respectively; and the AUC was 0.800. The cut-off value of SMI calculated from the ROC curve was 4.6 kg/m²; the sensitivity and specificity were 90.6% and 26.7%, respectively; and the AUC was 0.582. The AUC for the APMT model was significantly higher than the SMI model (P < 0.001).</p><p><strong>Conclusions: </strong>The results of this study show that the cut-off value of APMT for determining the gait independence was 13 mm. In addition, APMT had a higher accuracy of determining gait independence than SMI. This indicates that measuring APMT is more useful for predicting gait independence than SMI in community-dwelling older adults undergoing outpatient rehabilitation.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"615-623"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systemic inflammation is associated with gut microbiota diversity in post-stroke patients.","authors":"Yoshihiro Yoshimura, Hidetaka Wakabayashi, Fumihiko Nagano, Ayaka Matsumoto, Sayuri Shimazu, Ai Shiraishi, Yoshifumi Kido, Takahiro Bise, Takenori Hamada, Kouki Yoneda, Keisuke Maeda","doi":"10.1007/s41999-025-01159-2","DOIUrl":"10.1007/s41999-025-01159-2","url":null,"abstract":"<p><strong>Background: </strong>There is growing interest in gut microbiota and health outcomes. However, the relationship between systemic inflammation and gut microbiota diversity in hospitalized patients remains unclear. This study aimed to investigate the association in post-stroke rehabilitation patients.</p><p><strong>Methods: </strong>A cross-sectional study was conducted on post-stroke patients admitted to a rehabilitation hospital. Systemic inflammation was assessed using the modified Glasgow Prognostic Score (mGPS). Gut microbiota diversity was evaluated using three indices: Shannon index, Operational Taxonomic Unit (OTU) richness, and Faith's Phylogenetic Diversity (PD). Multiple linear regression analyses were performed to examine the relationship between mGPS and gut microbiota diversity indices, adjusting for potential confounders.</p><p><strong>Results: </strong>A total of 156 patients (mean age 78.4 years; 55.7% men) were analyzed. The median mGPS was 0 (interquartile range: 0-1), with GPS distribution: 61.8% scored 0, 25.7% scored 1, and 12.5% scored 2. After adjusting for confounders, mGPS was significantly and negatively associated with the Shannon index (B = -0.143, 95% CI -0.288 to -0.002, β = -0.177) and OTU richness (B = -17.832, 95% CI -24.349 to -3.951, β = -0.208). However, no significant association was observed between mGPS and Faith's PD (B = -1.155, 95% CI -2.464 to 0.189, β = -0.155).</p><p><strong>Conclusion: </strong>This study demonstrates a significant negative association between systemic inflammation and both quantitative and qualitative gut microbiota diversity in post-stroke patients.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"689-699"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teaching Comprehensive Geriatric Assessment (CGA) in medical education: a scoping review.","authors":"Regina Roller-Wirnsberger, Carolin Herzog, Sonja Lindner-Rabl, Mathias Schlögl, Maddalena Illario, Maria Cristina Polidori, Katrin Singler","doi":"10.1007/s41999-025-01157-4","DOIUrl":"10.1007/s41999-025-01157-4","url":null,"abstract":"<p><strong>Purpose: </strong>To gather and summarize evidence on educational and training formats for medical doctors in performing Comprehensive Geriatric Assessment (CGA) in under- and postgraduate medical education.</p><p><strong>Methods: </strong>A comprehensive literature review was conducted using the databases Medline, CINAHL, Cochrane and Embase to identify educational intervention studies and cohort studies related to CGA education and training for medical professionals. Additional references were incorporated through reference tracking. Studies included were then grouped according to competence level addressed during CGA trainings to create a current competence-based framework on educational tools to teach CGA to medical students and doctors.</p><p><strong>Results: </strong>Sixty eligible studies were identified, with 42 addressing the full implementation of CGA and 18 focusing on specific CGA domains. High variability in duration, intervention design and evaluation methods was consistently observed across the included studies.</p><p><strong>Conclusion: </strong>The findings underscore the need for further coordinated research in CGA education and training to consolidate evidence and pave the way to more innovative, high-quality healthcare systems capable of addressing the complexities of an aging society.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"425-433"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12014708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harmonious ageing: a narrative review of music therapy in the biomedical literature.","authors":"Shaz Raja, Ciara Barry, Rohit Upadhyay, Rana Alash, Méabh O'Raghallaigh, Róisín Hayes, Roman Romero-Ortuno","doi":"10.1007/s41999-024-01146-z","DOIUrl":"10.1007/s41999-024-01146-z","url":null,"abstract":"<p><strong>Purpose: </strong>As the global population of older adults rises, the United Nations Decade of Healthy Ageing (2021-2030) advocates for disease prevention, management, and enhancing overall wellbeing in older adults. We reviewed the MEDLINE literature under the MeSH term \"music therapy\" (MT), for its role in promoting healthy ageing.</p><p><strong>Methods: </strong>A systematic search of the MEDLINE biomedical database (Ovid) was conducted using \"MT\" and \"Ageing\" as keywords, retrieving relevant full-text studies in English. Preference was given to more recent studies with higher levels of evidence. The studies were categorised according to the biopsychosocial framework into physical, cognitive and social domains, and further subcategorised based on their relevance to disease prevention and management.</p><p><strong>Results: </strong>The initial search identified 1147 articles, of which 75 met inclusion criteria. Studies encompassed both MT and music interventions delivered by non-music therapists. Overall, studies showed benefits in the promotion of physical health, including enhancing exercise capacity and improving fitness among older adults. Results were promising in managing conditions such as Parkinson's disease and frailty. In the area of brain health, studies showed cognitive benefits, particularly in attention and processing speed among older adults. Socially, there was evidence of enhanced quality of life, reduced anxiety and depression, and improved social engagement, including in people living with dementia, underscoring the role of music in fostering emotional connections and mitigating caregiver stress.</p><p><strong>Conclusion: </strong>MT and interventions can enhance biopsychosocial health outcomes in older adults. Research should prioritise isolating MT's specific effects, standardising definitions and methodologies, and exploring therapeutic mechanisms.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"461-472"},"PeriodicalIF":3.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12014829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}