European Geriatric Medicine最新文献

{"title":"Frailty trajectories and mortality risk in community-dwelling older adults: a 9-year follow-up study.","authors":"Gabriela Cabett Cipolli, Daniela de Assumpção, Ivan Aprahamian, Mallak Khalid Alzahrani, Ligiana Pires Corona, Yeda Aparecida de Oliveira Duarte, Mônica Sanches Yassuda, Qian-Li Xue","doi":"10.1007/s41999-025-01177-0","DOIUrl":"https://doi.org/10.1007/s41999-025-01177-0","url":null,"abstract":"<p><strong>Purpose: </strong>Frailty is a well-established risk factor for adverse health outcomes, yet its dynamic nature and predictors remain partially understood. This study aimed to investigate factors influencing frailty transitions and mortality risk among community-dwelling older adults.</p><p><strong>Methods: </strong>We conducted a longitudinal study using a 9-year follow-up data from the Health, Well-being, and Aging Study (SABE, as known in Portuguese). A Markov model, fitted via multinomial logistic regression, identified factors independently associated with frailty transitions between waves. Four trajectory groups were identified: stable, worsening, improving, and fluctuating.</p><p><strong>Results: </strong>A total of 1399 individuals aged 60 and older (61.8% female) were enrolled, with a mean age of 73.9 (SD ± 9.2) years. Among frailty transitions, 37.8% remained stable, 56.4% worsened, 1.3% improved, and 4.4% fluctuated. After adjusting for baseline variables, we found that older age, cognitive impairment, multimorbidity, and depressive symptoms were significantly linked to a higher risk of being frail at the next visit. The mortality risk was associated with male sex, older age, frailty, cognitive impairment, and multimorbidity.</p><p><strong>Conclusion: </strong>Sociodemographic and health-related factors contribute to increased risk of experiencing frailty and mortality among community-dwelling older adults. Further research is needed to identify modifiable factors influencing frailty transitions.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SURGE-ahead postoperative delirium prediction: external validation and open-source library.","authors":"Thomas Derya Kocar, Philip Wolf, Christoph Leinert, Simone Brefka, Marina L Fotteler, Adriane Uihlein, Felix Wezel, Martin Wehling, Nuh Rahbari, Hans Kestler, Florian Gebhard, Dhayana Dallmeier, Michael Denkinger","doi":"10.1007/s41999-025-01180-5","DOIUrl":"https://doi.org/10.1007/s41999-025-01180-5","url":null,"abstract":"<p><strong>Purpose: </strong>In this prospective external validation study, we examined the performance of the Supporting SURgery with GEriatric Co-Management and AI (SURGE-Ahead) postoperative delirium (POD) prediction algorithm. SURGE-Ahead is a collaborative project that aims to develop a clinical decision support system that uses predictive models to support geriatric co-management in surgical wards. Delirium is a common complication in older adults after surgery, leading to poor outcomes and increased healthcare costs. Early and accurate prediction of POD is crucial for timely intervention and prevention strategies.</p><p><strong>Methods: </strong>The SURGE-Ahead algorithm utilizes a linear support vector machine model with a comprehensive set of 15 clinical and demographic features. In our validation, we analyzed 173 study participants, of which 50 developed POD.</p><p><strong>Results: </strong>The study found that the SURGE-Ahead POD prediction algorithm yielded state-of-the-art performance, using only preoperative data, with a receiver operating characteristics area under the curve of 0.86. In addition, the SURGE-Ahead algorithm exhibited good calibration as shown by a Brier Score of 0.14. The algorithm is openly available on GitHub, facilitating its implementation and adaptation to different surgical settings.</p><p><strong>Conclusion: </strong>Our findings contribute to the development of reliable POD prediction tools, ultimately supporting the improvement of patient care in hospitalized older adults.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of prescribing and health-related quality of life in older adults: a narrative review with a special focus on patients with atrial fibrillation and multimorbidity.","authors":"Cheima Amrouch, Deirdre A Lane, Amaia Calderón-Larrañaga, Mirko Petrovic, Delphine De Smedt","doi":"10.1007/s41999-025-01175-2","DOIUrl":"https://doi.org/10.1007/s41999-025-01175-2","url":null,"abstract":"<p><strong>Purpose: </strong>To summarise the association between potentially inappropriate prescribing (PIP) and health-related quality of life (HRQOL) in older adults, with a special focus on those with atrial fibrillation (AF) and multimorbidity, while exploring potential interventions to improve prescribing quality and their impact on HRQOL.</p><p><strong>Methods: </strong>A comprehensive search strategy was conducted in MEDLINE using the PubMed interface on August 16th, 2024, focusing on key terms related to \"potentially inappropriate prescribing\" and \"quality of life\". Additionally, the reference lists of included studies were screened. Only studies utilising validated assessment tools for HRQOL or measuring global self-perceived health status were considered. Studies involving populations with an average age of  ≥ 65 years were included.</p><p><strong>Results: </strong>Of the 1810 articles screened, 35 studies were included. The findings indicate that the quality of prescribing, independent of polypharmacy, may negatively influence HRQOL. The review identified a range of interventions aimed at improving prescribing quality among older adults, including pharmacist-driven, general practitioner-driven, and multidisciplinary approaches. Interventions were assessed among distinct population groups and specifically in residential care homes. While some interventions demonstrated improvements in prescribing quality, the overall evidence regarding their impact on HRQOL remains limited.</p><p><strong>Conclusion: </strong>The relationship between prescribing quality and HRQOL remains underexplored in older adults with AF and multimorbidity, despite the high prevalence of PIP. Effective pharmacotherapy should be coupled with a comprehensive assessment of patients' clinical and functional parameters, considering their HRQOL. Adopting a multidisciplinary, integrated, patient-centred approach is essential for sustainable and appropriate prescribing practices and may enhance HRQOL.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of mood disturbance in older adults: a longitudinal cohort study.","authors":"Feng-Yi Wang, Ling-Jie Fan, Lin-Nan Huo, Yang Lin, Ren-Gang Zhang, Yong-Hong Yang, Quan Wei","doi":"10.1007/s41999-025-01178-z","DOIUrl":"https://doi.org/10.1007/s41999-025-01178-z","url":null,"abstract":"<p><strong>Purpose: </strong>Given the significant mental health challenges faced by the aging population, this study aimed to identify key predictors of mood disturbances among older adults, focusing on socioeconomic, health, and cognitive factors.</p><p><strong>Methods: </strong>This post-hoc analysis utilized publicly available data from the National Health and Aging Trends Study (NHATS), a nationally representative longitudinal cohort study conducted in the United States. The analysis included 2,820 adults aged 65 years and above who were followed for three years (age average range 75-79 years, 54.7% female).</p><p><strong>Results: </strong>During the follow-up period, 21.8% of participants developed new-onset mood disturbances. High-income status is associated with decreased risk (OR 0.71, 95% CI 0.52-0.96), while being Black showed a risk effect compared to White participants (OR 1.38, 95% CI 1.06-1.29). With not good health status (OR 1.58, 95% CI 1.04-2.41), without presence of diabetes (OR 0.74, 95% CI 0.58-0.95), and poor memory status (OR 2.14, 95% CI 1.10-4.15) were significant predictors. Without fear of falling (OR 0.77, 95% CI 0.61-0.97) and increased physical performance (OR 0.94, 95% CI 0.91-0.98) also decreased risk. Income-stratified analysis revealed that low-income groups were particularly affected by cognitive function, middle-income by health status, and high-income by physical activity levels.</p><p><strong>Conclusion: </strong>Socioeconomic status, race, health conditions, and cognitive function are significant predictors of mood disturbances in older adults. These findings suggest the importance of developing targeted interventions based on income levels and addressing modifiable risk factors.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Approaches to characterising multimorbidity in older people accessing hospital care: a scoping review.","authors":"Jonathan G Bunn, Lewis Steell, Susan J Hillman, Miles D Witham, Avan A Sayer, Rachel Cooper","doi":"10.1007/s41999-025-01166-3","DOIUrl":"https://doi.org/10.1007/s41999-025-01166-3","url":null,"abstract":"<p><strong>Purpose: </strong>An increasing proportion of older adults accessing hospital care are living with multimorbidity, with a high degree of complexity of multimorbidity in older hospital populations expected. We aimed to assess approaches taken to characterise multimorbidity in older adults accessing hospital care, including how complexity is considered.</p><p><strong>Methods: </strong>Following established scoping review guidelines, all published studies that characterised multimorbidity in a hospital population, with average age ≥ 65 years, were identified via a prespecified search strategy. Six electronic databases were searched to identify peer-reviewed literature published to September 2023 meeting eligibility criteria. Screening was undertaken by two independent reviewers, and data extracted using a standard proforma.</p><p><strong>Results: </strong>Of 5305 titles and abstracts screened, 75 papers, reporting on 72 unique study populations across 24 countries, met inclusion criteria. There was heterogeneity in most aspects of characterisation. Multimorbidity was defined in 43% (n = 31/72) of studies; most (n = 59/72, 82%) aimed to describe a multimorbidity-outcome association. Number of conditions considered ranged from 2 to 285 and weighted indices were used as a measure of multimorbidity in 75% (n = 54/72) of studies, with 56% (n = 40/72) using a version of the Charlson Comorbidity Index. Complexity was explicitly studied in 17% (n = 12/72) of studies.</p><p><strong>Discussion: </strong>Our review highlights heterogeneity in characterisation of multimorbidity in older adults accessing hospital care, with limited consideration of complexity. As the proportion of older adults accessing hospital care who are living with multimorbidity increases, better characterisation of their multiple conditions and associated complexity is a priority to ensure delivery of appropriately tailored care.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of long-term prognosis of older patients after a first fall according to economic status.","authors":"Ana García-Martínez, Lourdes Artajona, Sergio García-Rosa, Victoria Torres Machado, Adriana Gil-Rodrigo, Carmen Pérez-Fonseca, Javier Jacob, Pere Llorens, Pablo Herrero, Francisco J Martín-Sánchez, Andrea Bellido, Montserrat Lázaro Del Nogal, Òscar Miró","doi":"10.1007/s41999-025-01174-3","DOIUrl":"https://doi.org/10.1007/s41999-025-01174-3","url":null,"abstract":"<p><strong>Purpose: </strong>Accidental falls are sentinel events of poor outcomes and future healthcare needs in older individuals. Understanding the effect of socioeconomic status (SES) on these needs is important for healthcare planning. The study aimed to investigate the association between SES and outcomes in a cohort of older fallers.</p><p><strong>Methods: </strong>A multicentre study was conducted including patients aged 65 years or older attending the emergency department (ED) of five Spanish hospitals after a first fall from September 1st, 2014, to August 31st, 2015. Sociodemographic features and past medical history were recorded. SES was evaluated using a proxy based on the mean income level at patients' zip code area. Outcomes after 5 years of the index fall included all-cause death, new fall-related visits to the ED, and fall-related fractures. Logistic regression was used to investigate the association between SES and outcomes.</p><p><strong>Results: </strong>The cohort included 716 patients (median age 79 years [IQR 72-85], 68% female). There were 439 patients (61.3%) with low and 277 (38.7%) with high SES. The group with low SES had significantly higher prevalence of depression (31.3% vs. 23%), polypharmacy (57.5% vs. 45.5%), or visual impairment (58.7% vs. 50.6%), whereas the percentage of patients with dependency (42.3% vs. 53.1%) or living alone (15.1% vs. 22.4%) was higher in the group with high SES. At the end of the 5-year follow-up, 250 patients (35.4%) died, 271 (49.3%) had a new fall-related visit, and 104 (20.6%) suffered a fall with fracture. None of these outcomes was associated with SES, irrespective of whether SES was considered as a dichotomous or a continuous variable.</p><p><strong>Conclusion: </strong>There are significant clinical differences based on SES in older patients attending the ED after a first fall. However, living in areas with lower SES was not associated with long-term outcomes in the context of a universal healthcare system. Further research is necessary to understand the interplay between SES and prognosis in this population.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges, current innovations, and opportunities for managing type 2 diabetes in frail older adults: a position paper of the European Geriatric Medicine Society (EuGMS)-Special Interest Group in Diabetes.","authors":"Virginia Boccardi, Gülistan Bahat, Cafer Balci, Isabelle Bourdel-Marchasson, Antoine Christiaens, Lorenzo Maria Donini, Sibel Cavdar, Stefania Maggi, Serdar Özkök, Tajana Pavic, Stany Perkisas, Stefano Volpato, Muhammad Shoaib Zaidi, Andrej Zeyfang, Alan J Sinclair","doi":"10.1007/s41999-025-01168-1","DOIUrl":"https://doi.org/10.1007/s41999-025-01168-1","url":null,"abstract":"<p><strong>Purpose: </strong>This position paper aims to address the challenges of managing type 2 diabetes mellitus (T2DM) in frail older adults, a diverse and growing demographic with significant variability in health status. The primary research questions are: How can frailty assessment be effectively integrated into diabetes care? What strategies can optimize glycaemic control and outcomes for frail older adults? How can innovative tools and technologies, including artificial intelligence (AI), improve the management of this population?</p><p><strong>Methods: </strong>The paper uses the 5 I's framework (Identification, Innovation, Individualization, Integration, Intelligence) to integrate frailty into diabetes care, proposing strategies such as frailty tools, novel therapies, digital technologies, and AI systems. It also examines metabolic heterogeneity, highlighting anorexic-malnourished and sarcopenic-obese phenotypes.</p><p><strong>Results: </strong>The proposed framework highlights the importance of tailoring glycaemic targets to frailty levels, prioritizing quality of life, and minimizing treatment burden. Strategies such as leveraging AI tools are emphasized for their potential to enhance personalized care. The distinct management needs of the two metabolic phenotypes are outlined, with specific recommendations for each group.</p><p><strong>Conclusion: </strong>This paper calls for a holistic, patient-centered approach to diabetes care for frail older adults, ensuring equity in access to innovations and prioritizing quality of life. It highlights the need for research to fill evidence gaps, refine therapies, and improve healthcare integration for better outcomes in this vulnerable group.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying long-term patterns and predictors of concurrent psychotropic medicine use in residential aged care using group-based multi-trajectory modelling: the 'MEDTRAC-Psychotropics' longitudinal cohort study.","authors":"Nasir Wabe, Isabelle Meulenbroeks, Desiree Chantelle Firempong, Rachel Urwin, Andrea Timothy, Magdalena Z Raban, Virginia Mumford, Johanna Westbrook","doi":"10.1007/s41999-025-01171-6","DOIUrl":"https://doi.org/10.1007/s41999-025-01171-6","url":null,"abstract":"<p><strong>Purpose: </strong>Psychotropic medicines are commonly used in residential aged care facilities (RACFs) despite notable safety concerns. No prior studies have examined the longitudinal concurrent use of psychotropic medicines. We aimed to identify trajectories of concurrent use of three psychotropic medication classes over time and determine predictors of trajectory group membership for residents with and without dementia.</p><p><strong>Methods: </strong>A retrospective longitudinal cohort study including 30 RACFs in Sydney, Australia. The study participants included 2837 newly admitted permanent residents (n = 1344 with dementia) aged ≥ 65 years. We monitored weekly exposure to three psychotropic classes-antidepressants, antipsychotics, and anxiolytics/hypnotics-over three years. We used group-based multi-trajectory modelling to identify concurrent psychotropic medicine use.</p><p><strong>Results: </strong>At baseline, 38.5%, 19.6%, and 16.7% of residents with dementia received antidepressants, antipsychotics, and anxiolytics/hypnotics, respectively, compared to 32.8%, 7.1%, and 16.5% in residents without dementia. The concurrent use of multiple psychotropic classes occurred in 23.3% of non-dementia and 31.6% of dementia cohorts. The model identified 6-group and 4-group trajectories as the optimal fit for dementia and non-dementia cohorts, respectively. Psychotropic use trajectories mostly remained stable over time in non-dementia cohorts, while dementia cohorts showed more diverse and fluctuating use. Multinomial logistic regressions identified eleven predictors of trajectory membership in dementia and nine in non-dementia cohorts.</p><p><strong>Conclusion: </strong>One in three residents with dementia and one in five without dementia concurrently use multiple psychotropics often for extended periods, which may put residents at risk. Further research should assess the appropriateness of such use and consider strategies for improving health outcomes.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143505221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute readmissions among care home residents aged 65+ years: a register-based study.","authors":"Gitte Schultz Kristensen, Jens Søndergaard, Karen Andersen-Ranberg, Christian Backer Mogensen","doi":"10.1007/s41999-025-01162-7","DOIUrl":"https://doi.org/10.1007/s41999-025-01162-7","url":null,"abstract":"<p><strong>Purpose: </strong>Care home residents are characterised by multimorbidity, cognitive impairment, and physical disabilities, resulting in a high risk of acute admissions and readmissions. The risk factors for acute readmissions may differ from those affecting older adults in the community. This study aims to identify risk factors associated with acute readmissions among care home residents within 30 days of discharge from an acute hospital admission.</p><p><strong>Methods: </strong>We included all care home residents aged 65 + years living in Southern Jutland in Denmark from 2014 to 2019 who were discharged from their first acute hospital admission (lasting 12 + h) in the study period. Data on baseline characteristics, index admissions, 30-day readmissions, and mortality were obtained from the highly valid Danish national health registries. Cox regression was employed to identify factors associated with acute readmissions.</p><p><strong>Results: </strong>The care home residents had a mean age of 83.9-86.2 at index admission, and 57.0-62.3% were women. Of 2108 initial admissions, 328 (15.6%) resulted in an acute readmission, and 302 (14.3%) died within 30 days of follow-up. Notably, nearly half of the readmissions occurred within 1 week of discharge. Being a new care home resident (care home residency < 3 months) was associated with acute readmission (HR 1.40), as was a medical history of cancer (HR 1.31), diabetes (HR 1.45), atrial fibrillation (HR 1.54), and COPD/asthma (HR 1.36). Conversely, dementia was associated with a significantly lower risk of acute readmission (HR 0.71).</p><p><strong>Conclusion: </strong>Our findings can help identify care home residents at elevated risk of readmission shortly after discharge.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of behavioural and psychological symptoms of dementia: a pragmatic scoping review of European guidelines and literature.","authors":"Alessandra Coin, Elsa Brew-Girard, Ellen Tracey, Vincenza Frisardi, Federica Piccione, Costanza Muraro, Eleonora Mizzon, Susan D Shenkin, Pinar Soysal, Tomas Welsh, Hanna-Maria Roitto","doi":"10.1007/s41999-025-01155-6","DOIUrl":"https://doi.org/10.1007/s41999-025-01155-6","url":null,"abstract":"<p><strong>Purpose: </strong>Dementia prevalence within the European Union (EU) is expected to double by 2050. Behavioural and Psychological Symptoms of Dementia (BPSD) are common, causing burden to patients and caregivers. This pragmatic scoping review aims to synthesize recommendations of European BPSD management guidelines and literature, highlighting areas of consensus and disagreement.</p><p><strong>Methods: </strong>An electronic literature search, including Medline, PsychINFO, and CINAHL, and Internet search for grey literature were undertaken to identify published BPSD guidelines from the EU, European Economic Area (EEA) and UK, supplemented by contacting EU member countries of European Geriatric Medicine Society (EuGMS).</p><p><strong>Results: </strong>The literature search found 11 papers describing BPSD management. Of the 32 countries of interest, 22 guidelines were sourced (five confirmed no guidelines, five did not respond). There was a general consensus between the guidelines, as all recommended comprehensive assessment and individualised approaches, with non-pharmacological therapies as first line, but there was disagreement around specific therapies. Psycho-education was most commonly recommended (15 countries). There was general agreement that pharmacological treatment should be used as an adjunct to non-pharmacological interventions, but recommendations differed between medication groups. Short-term atypical antipsychotics were most commonly recommended, especially risperidone (18 countries). 15 countries recommended acetylcholinesterase inhibitors and 12 memantine. 16 countries recommended the use of SSRIs. Recommendations for the use of sedative medications and antiepileptics varied.</p><p><strong>Conclusions: </strong>This study provides a broad, inclusive overview of current European guidelines for the management of BPSD, demonstrating significant variability. Clinical practice in dementia care throughout Europe needs to be optimised and standardised.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}