European Geriatric Medicine最新文献_第10页

Associations of nutritional intake and inflammatory factors with sarcopenia in community-dwelling older adults: a cross-sectional study. 营养摄入和炎症因子与社区老年人肌肉减少症的关联：一项横断面研究。

IF 3.5 3区医学

European Geriatric Medicine Pub Date : 2025-02-01 Epub Date: 2025-01-11 DOI: 10.1007/s41999-024-01147-y

Jiaqian Xu, Shuangshuang Jia, Ruining Xie, Xin Yan, Lingzhi Chen, Xiaoyu Cheng, Li Bai, Yaqing Li, Yujing Wang, Yi Qiao

{"title":"Associations of nutritional intake and inflammatory factors with sarcopenia in community-dwelling older adults: a cross-sectional study.","authors":"Jiaqian Xu, Shuangshuang Jia, Ruining Xie, Xin Yan, Lingzhi Chen, Xiaoyu Cheng, Li Bai, Yaqing Li, Yujing Wang, Yi Qiao","doi":"10.1007/s41999-024-01147-y","DOIUrl":"10.1007/s41999-024-01147-y","url":null,"abstract":"Purpose: Sarcopenia is an age-related disease that is related to nutritional intake and chronic low-grade inflammation. The aim of this study was to investigate the association of dietary intake, inflammatory markers and sarcopenia among the community-dwelling older adults.Methods: A total of 1001 older adults aged 60 and above were recruited. According to the criteria established by the Asian Working Group for Sarcopenia 2019, this paper assessed the presence of sarcopenia and using a Food Frequency Questionnaire to evaluate daily dietary intake. Serum levels of inflammatory markers were measured using the ELISA method.Results: A total of 1001 participants took part in the study (mean 70.6 years), comprising 396 males and 605 females, the prevalence of sarcopenia was 19.6%. Multivariate analysis revealed that high levels of leucine, methionine, threonine, histidine, aspartic acid, calcium, zinc, and vitamin C were associated with a lower risk of sarcopenia. Higher dietary inflammatory index scores were associated with a higher risk of sarcopenia (OR 1.67, 95% CI 1.12-2.47). Higher tumor necrosis factor-like weak inducer of apoptosis (TWEAK) (OR 1.04, 95% CI 1.02-1.07) was associated with a higher risk of sarcopenia, and a lower skeletal muscle mass, strength, and physical function. Conversely, higher insulin-like growth factor-1 (IGF-1) (OR 0.83, 95% CI 0.74-0.94) and glutathione S-transferase (GST) (OR 0.75, 95% CI 0.61-0.91) were associated with a lower risk of sarcopenia.Conclusions: This cross-sectional study revealed alterations in amino acid and micronutrient intake among older adults with sarcopenia. The levels of TWEAK were associated with an increased risk of sarcopenia, whereas IGF-1 and GST were associated with a reduced risk of sarcopenia.","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"33-44"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the efficacy of AI-enhanced telerehabilitation in sarcopenic older individuals. 研究人工智能增强型远程康复对肌肉疏松老年人的疗效。

IF 3.5 3区医学

European Geriatric Medicine Pub Date : 2025-02-01 Epub Date: 2024-10-25 DOI: 10.1007/s41999-024-01082-y

Meiqi Wei, Deyu Meng, Shichun He, Zongnan Lv, Hongzhi Guo, Guang Yang, Ziheng Wang

{"title":"Investigating the efficacy of AI-enhanced telerehabilitation in sarcopenic older individuals.","authors":"Meiqi Wei, Deyu Meng, Shichun He, Zongnan Lv, Hongzhi Guo, Guang Yang, Ziheng Wang","doi":"10.1007/s41999-024-01082-y","DOIUrl":"10.1007/s41999-024-01082-y","url":null,"abstract":"Objective: This study explores the effectiveness of 3D pose estimation technology in Yi Jin Jing (a traditional Chinese exercise) interventions for sarcopenic older individuals.Design: A randomized controlled trial involving 93 participants (mean age: 71.64 ± 7.09 years; 41 males and 52 females) divided into three groups: a face-to-face offline traditional training group (OFFG), a general remote online training group (ONG), and an AI-based online remote training group (AIONG).Methods: Participants in each group underwent their respective training programs. The effectiveness of the interventions was measured using Appendicular Skeletal Muscle Mass Index, Grip Strength, 6-meter Walking Speed, Timed-Up-and-Go Test, and Quality of Life assessments.Results: Significant improvements were observed across all groups in ASMI, Grip Strength, 6-meter Walking Speed, TUGT, and QoL. However, there were no statistically significant differences between the groups in terms of the magnitude of these improvements. AIONG showed outcomes comparable to OFFG and ONG methods.Conclusions: AI-based telerehabilitation with 3D pose estimation is a viable and effective alternative for remote exercise interventions. It offers precise guidance and enhances the quality of rehabilitation training, demonstrating outcomes comparable to traditional and general online methods.","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"115-123"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Artificial Intelligence ageist? Correspondence. 人工智能是年龄歧视吗？信件。

IF 3.5 3区医学

European Geriatric Medicine Pub Date : 2025-02-01 Epub Date: 2025-02-11 DOI: 10.1007/s41999-024-01116-5

Amnuay Kleebayoon, Hinpetch Daungsupawong, Viroj Wiwanitkit

引用次数: 0

Response to the letter to the editor following the article 'Is artificial intelligence ageist?' 对《人工智能是年龄歧视吗？》一文后致编辑的信的回应

IF 3.5 3区医学

European Geriatric Medicine Pub Date : 2025-02-01 Epub Date: 2024-11-22 DOI: 10.1007/s41999-024-01110-x

Yanira Aranda Rubio

引用次数: 0

Cross-sectional and longitudinal associations between glycaemic measures and grip strength in people without diabetes in the UK Biobank cohort study. 在英国生物银行队列研究中，无糖尿病患者血糖测量和握力之间的横断面和纵向关联。

IF 3.5 3区医学

European Geriatric Medicine Pub Date : 2025-02-01 Epub Date: 2024-11-29 DOI: 10.1007/s41999-024-01119-2

Antoneta Granic, Rachel Cooper, Christopher Hurst, Susan J Hillman, Richard M Dodds, Miles D Witham, Avan A Sayer

{"title":"Cross-sectional and longitudinal associations between glycaemic measures and grip strength in people without diabetes in the UK Biobank cohort study.","authors":"Antoneta Granic, Rachel Cooper, Christopher Hurst, Susan J Hillman, Richard M Dodds, Miles D Witham, Avan A Sayer","doi":"10.1007/s41999-024-01119-2","DOIUrl":"10.1007/s41999-024-01119-2","url":null,"abstract":"Purpose: To investigate associations between glycaemic measures (HbA1c, random glucose), and grip strength (GS) in adults without prevalent diabetes.Methods: We included 381,715 UK Biobank participants aged 38-73 years without diabetes (any type) with complete baseline measures for GS and HbA1c (main analyses), and glucose (supplementary analyses). Cross-sectional sex- and age-stratified associations between each glycaemic measure, GS, and probable sarcopenia (low GS) were examined with regression analyses. Changes in GS over 8.9 years were classified into four groups (decline, stable low, stable high, or reference (increase or maintained within the normal range)) in 36,228 participants and associations with baseline glycaemic measures explored using multinomial regression.Results: Higher HbA1c (mmol/mol) was associated with weaker mean GS (kg) (regression coefficient and 95% confidence intervals (CI): - 0.08 (- 0.09, - 0.07)), and increased odds of probable sarcopenia (odds ratio (OR) and 95% CIs: 1.02 (95% CI: 1.01, 1.02)) in males and across the age groups. In females, higher HbA1c was associated with weaker mean GS only in mid-life (e.g., 50-59 years: - 0.06 (- 0.07, - 0.05)). In males, but not in females with repeated GS, higher HbA1c was associated with decreased odds of stable high (0.97 (0.96, 0.99) and increased odds of stable low (1.03 (1.01, 1.04)) GS pattern (0.98 (0.97, 0.980)) over the follow-up. The results for glucose in supplementary analyses were mixed, especially in females.Conclusions: The associations between HbA1c and GS in people without diabetes warrant replication and consideration of the effect on muscle strength when interventions to promote normoglycaemia are trialled.","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"67-77"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Healthcare costs in relation to kidney function among older people: the SCOPE study. 与老年人肾功能有关的医疗费用：SCOPE 研究。

IF 3.5 3区医学

European Geriatric Medicine Pub Date : 2025-02-01 Epub Date: 2024-11-13 DOI: 10.1007/s41999-024-01086-8

Francesco Balducci, Mirko Di Rosa, Regina Roller-Wirnsberger, Gerhard Wirnsberger, Francesco Mattace-Raso, Lisanne Tap, Francesc Formiga, Rafael Moreno-González, Tomasz Kostka, Agnieszka Guligowska, Rada Artzi-Medvedik, Itshak Melzer, Christian Weingart, Cornel Sieber, Johan Ärnlöv, Axel C Carlsson, Fabrizia Lattanzio, Andrea Corsonello

{"title":"Healthcare costs in relation to kidney function among older people: the SCOPE study.","authors":"Francesco Balducci, Mirko Di Rosa, Regina Roller-Wirnsberger, Gerhard Wirnsberger, Francesco Mattace-Raso, Lisanne Tap, Francesc Formiga, Rafael Moreno-González, Tomasz Kostka, Agnieszka Guligowska, Rada Artzi-Medvedik, Itshak Melzer, Christian Weingart, Cornel Sieber, Johan Ärnlöv, Axel C Carlsson, Fabrizia Lattanzio, Andrea Corsonello","doi":"10.1007/s41999-024-01086-8","DOIUrl":"10.1007/s41999-024-01086-8","url":null,"abstract":"Purpose: In this study, a comprehensive analysis of costs of chronic kidney disease (CKD) was performed, to understand factors associated with the economic burden of the disease in a multicentre international framework.Methods: The impact on costs of demographics, socio-economics, clinical, and functional variables was tested in 2204 subjects aged 75 years or more attending outpatient clinics in Europe using a multicentre 2-year prospective cohort study. By means of collected resources consumption and unit cost data a comprehensive cost database was built and then investigated using multilevel regression modeling.Results: Overall, hospitalization, medications and specialist visits were the main cost items, with a notable variability among countries. Estimated yearly costs were 4478€ ± 9804€, rising up to 6683€ ± 10,953€ for subjects with estimated Glomerular Filtration Rate (eGFR) < 30. Costs increased significantly according to the severity of the disease, gender and age. Clinical and functional covariates were also significantly associated with CKD-related total costs, even after correcting for the inter-country variability.Conclusion: Findings corroborate the importance of multidimensional assessment of participants with CKD, as multimorbidity and functional disability produce a detrimental impact on participant's prognosis and cost of care. Preservation of functional impairment and adequate management of comorbidities may thus help decreasing the overall consumption on health care resources in CKD patients, especially in older people.","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"135-148"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Moving from just measuring, to acting on frailty in specialties outside geriatrics. 从仅仅测量，到在老年医学以外的专业中对虚弱采取行动。

IF 3.5 3区医学

European Geriatric Medicine Pub Date : 2025-02-01 DOI: 10.1007/s41999-025-01154-7

John S M Houghton

引用次数: 0

Exploring how falls prevention practitioners assess and manage concerns about falling. 探索跌倒预防从业人员如何评估和管理对跌倒的担忧。

IF 3.5 3区医学

European Geriatric Medicine Pub Date : 2025-02-01 Epub Date: 2024-12-17 DOI: 10.1007/s41999-024-01127-2

Bianca Nicklen, Kim Delbaere, Toby J Ellmers

{"title":"Exploring how falls prevention practitioners assess and manage concerns about falling.","authors":"Bianca Nicklen, Kim Delbaere, Toby J Ellmers","doi":"10.1007/s41999-024-01127-2","DOIUrl":"10.1007/s41999-024-01127-2","url":null,"abstract":"Background: Concerns about falling (CaF) are common in older adults. They can lead to various negative outcomes, including an increased risk for future falls. The Worlds Falls Guidelines recently published recommendations for assessing and treating CaF. However, the extent to which these guidelines have been adopted into falls prevention practice (in addition to the barriers preventing implementation) are currently unknown.Methods: A cross-sectional survey was completed by 114 healthcare professionals working in falls prevention and rehabilitation services in the UK and Ireland. The survey explored their experiences and perceptions regarding the management and assessment of CaF.Results: Only 39% of respondents reported using the Falls Efficacy Scale-International (FES-I), a tool recommended by the World Falls Guidelines for assessing CaF. Healthcare professionals in hospital settings were significantly less likely to use the FES-I compared to those working in the community (X2 = 6.324, p = 0.043). While there was no significant difference between settings regarding the type of intervention used to manage CaF, only about 50% of participants adopted a holistic approach combining physical and psychological strategies as recommended by the World Falls Guidelines. The most commonly identified barriers to clinical management of CaF were a lack of both time and perceived effective interventions, particularly for those working within hospital settings (X2 = 6.209, p = 0.013 and X2 = 3.752, p = 0.053, respectively).Conclusion: These findings indicate low levels of adoption of the World Falls Guidelines recommendations for assessing and managing CaF, especially in hospital settings. Future work should focus on addressing these barriers to maximise the clinical adoption of these recommendations.","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"219-227"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Circulating irisin levels in patients with sarcopenia: a systematic review and meta-analysis. 肌肉疏松症患者的循环鸢尾素水平：系统回顾与荟萃分析。

IF 3.5 3区医学

European Geriatric Medicine Pub Date : 2025-02-01 Epub Date: 2024-11-19 DOI: 10.1007/s41999-024-01097-5

Liangchuan Zhang, Yating Peng, Yuan Kong, Xue Zhang, Zetian Li, Hong Jia

{"title":"Circulating irisin levels in patients with sarcopenia: a systematic review and meta-analysis.","authors":"Liangchuan Zhang, Yating Peng, Yuan Kong, Xue Zhang, Zetian Li, Hong Jia","doi":"10.1007/s41999-024-01097-5","DOIUrl":"10.1007/s41999-024-01097-5","url":null,"abstract":"Objective: During the aging process, a decrease in irisin levels is associated with numerous bone and muscle diseases. This study aims to provide evidence of circulating irisin levels in patients with sarcopenia.Methods: This systematic review was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standard and the recommendations of the Cochrane Collaboration. A comprehensive search was conducted in PubMed, Embase, Web of Science databases, and other sources from their establishment until August 2023. The Review Manager software version 5.4 was used to calculate the standard mean difference (SMD). I2 statistics measured heterogeneity.Results: 12 studies involving 2133 participants who met the inclusion criteria were analyzed. We found that irisin levels were significantly lower in patients with sarcopenia (SMD: - 1.28; 95% CI - 1.65, - 0.90; I2 = 92% P < 0.001). Sensitivity analysis confirmed the robustness of this result. The correlation results showed that there was a positive correlation between the levels of circulating irisin and muscle mass (r value 0.62, 95% CI 0.31, 0.81; P < 0.001) and strength (r value 0.47, 95% CI 0.23, 0.66; P < 0.001), but no statistical correlation between irisin and muscle function (The P-values for gait speed and chair test time are 0.5523 and 0.1467, respectively).Conclusion: No matter the study area, study design, blood samples, or diagnostic criteria, the concentration of circulating irisin in patients with sarcopenia was lower than that in the control group.","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"5-13"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of oral frailty with falls in long-term care residents. 长期护理居民口腔虚弱与跌倒的关系。

IF 3.5 3区医学

European Geriatric Medicine Pub Date : 2025-02-01 Epub Date: 2024-11-06 DOI: 10.1007/s41999-024-01088-6

Taija Puranen, Kaija Hiltunen, Kaisu H Pitkälä, Hanna-Maria Roitto, Päivi Mäntylä, Riitta K T Saarela

{"title":"Association of oral frailty with falls in long-term care residents.","authors":"Taija Puranen, Kaija Hiltunen, Kaisu H Pitkälä, Hanna-Maria Roitto, Päivi Mäntylä, Riitta K T Saarela","doi":"10.1007/s41999-024-01088-6","DOIUrl":"10.1007/s41999-024-01088-6","url":null,"abstract":"Purpose: We investigated the relationship between oral frailty (OFr) and falls among long-term care residents.Methods: Residents (N = 254, mean age 84 y, 79% women) participated in this longitudinal cohort study in 2018-2021. OFr was defined by six signs. Demographics, diagnoses, and medications were retrieved from the medical records. Frailty phenotype, sarcopenia and disability were assessed. Number of falls was collected from medical records over 12 months following baseline assessment.Results: Of participants, 35% fell during follow-up. Of the fallers, 28% were bedridden or needed a wheelchair; among non-fallers, this figure was 73%. In logistic regression analysis after adjusting for age, sex, BMI, stroke, dementia, diabetes, coronary heart disease, number of medications, mobility, walking speed and sarcopenia, OFr did not predict falls (OR for severe OFr 0.13 (95% CI 0.01-1.27). Male sex predicted falls.Conclusions: No association was found between severe OFr and falls over a 12-month follow-up.","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"191-195"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0