European Geriatric Medicine最新文献

{"title":"Applying both the 30-s and the 5-repetition sit-to-stand tests captures dissimilar groups and a broader spectrum of physical abilities in mobility-limited older individuals: results from the BIOFRAIL study.","authors":"P Hansen, H Nygaard, J Ryg, M T Kristensen, C Suetta","doi":"10.1007/s41999-024-01115-6","DOIUrl":"https://doi.org/10.1007/s41999-024-01115-6","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to assess differences among older patients demonstrating low STS performance in the 30 s-STS and/or the 5r-STS.</p><p><strong>Methods: </strong>30 s-STS and 5r-STS were used to assess lower limb muscle strength and function in older adults. Analysis involved 376 patients (≥ 65 years) from a geriatric outpatient clinic for fall assessment.</p><p><strong>Results: </strong>The mean age of patients was 79.8 (± 6.1) years (67% female). In total, 40.6% had low STS performance with 9.3% presenting only low 30 s-STS, 9.8% only low 5r-STS, and 21.5% low STS performance in both tests. Patients with low STS performance in both tests had lower gait speed, were more often frail, and had more prior falls compared to patients with low STS performance in one test only.</p><p><strong>Conclusion: </strong>The two STS tests are not interchangeable, and the use of both STS tests capture a wider range of physical abilities in mobility-limited older adults.</p><p><strong>Clinical trial registration: </strong>NCT05795556.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wearable sensors for monitoring caregivers of people with dementia: a scoping review.","authors":"Francesco Palmese, Ylenia Druda, Vittoria Benintende, Domenico Fuda, Marcello Sicbaldi, Paola Di Florio, Abdul Haleem Butt, Giorgio Bedogni, Lorenzo Chiari, Alessandro Silvani, Marco Domenicali","doi":"10.1007/s41999-024-01113-8","DOIUrl":"https://doi.org/10.1007/s41999-024-01113-8","url":null,"abstract":"<p><strong>Purpose: </strong>Caregivers of people with dementia often face a demanding care burden that may lead to adverse physical and psychological outcomes. Wearable sensors are becoming a valuable tool for preventive care. We aimed to provide the first systematic map of the published evidence on the use of wearable sensors to monitor caregivers of people with dementia.</p><p><strong>Methods: </strong>We developed a scoping review protocol following the PRISMA-ScR guidelines. The searches were conducted on PubMed, Scopus, Web of Science, PsycInfo, and IEEE.</p><p><strong>Results: </strong>We identified 1394 articles and selected 37 reports. Sleep measures were the outcome most frequently evaluated (28/37). Among these reports, eight assessed the effectiveness of different interventions targeting both caregivers and care-receivers and found no improvement in caregivers' sleep; three compared the sleep of caregivers of people with dementia with controls, with conflicting results; five focused on depressive symptoms; and four associated these symptoms with shorter sleep duration and greater sleep fragmentation and sleep latency. A single device was used in 33 reports and sensors were most commonly placed at the wrist (33/37). Most studies monitored caregivers for 1 or more weeks (27/37).</p><p><strong>Conclusion: </strong>Wearable sensors were mainly used to monitor sleep in informal caregivers of people with dementia based on wrist accelerometry for 1 or more weeks, with conflicting results. There is a need for targeted studies with adequate control groups to identify factors associated with sleep alterations in informal and formal caregivers of people with dementia, leveraging multi-sensor setups with the inclusion of autonomic nervous system metrics.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142774009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review on dysphagia treatments for persons living with dementia.","authors":"Charis Tsz Wun Chan, Tsz Yin Wu, Ivy Cheng","doi":"10.1007/s41999-024-01107-6","DOIUrl":"10.1007/s41999-024-01107-6","url":null,"abstract":"<p><strong>Purpose: </strong>Dysphagia in persons living with dementia (PLWD) is raising concern due to the absence of swallowing treatments specific to this population. Dysphagia can result in detrimental effects, such as malnutrition, dehydration, and aspiration pneumonia. This systematic review aimed to evaluate the existing literature on dysphagia management of PLWD and reveal their limitations to facilitate clinical practitioners in decision-making.</p><p><strong>Methods: </strong>Five electronic databases were searched systematically from the date of inception to January 2024 by two independent reviewers. Eligible studies investigated any treatments with outcome measurements evaluating swallowing function. Qualitative analyses were performed.</p><p><strong>Results: </strong>A total of 10 studies, involving 1360 participants, were included in the systematic review. They were analyzed qualitatively and evaluated for quality. Studies included were observational (n = 5) with prospective or retrospective designs, and randomized controlled trials (n = 5). Compensatory, rehabilitative, stimulation, and pharmacological treatments were addressed.</p><p><strong>Conclusion: </strong>There is currently limited evidence available revealing the efficacy of dysphagia treatments for PLWD. Based on the current evidence, no definitive conclusions can be drawn on which treatments are more effective for this population. In the future, more randomized controlled trials with large sample sizes investigating the long-term effects of treatments are warranted.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"1573-1585"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632040/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment tools addressing avoidable care transitions in older adults: a systematic literature review.","authors":"Rustem Makhmutov, Alicia Calle Egusquiza, Cristina Roqueta Guillen, Eva-Maria Amor Fernandez, Gabriele Meyer, Moriah E Ellen, Steffen Fleischer, Anna Renom Guiteras","doi":"10.1007/s41999-024-01106-7","DOIUrl":"10.1007/s41999-024-01106-7","url":null,"abstract":"<p><strong>Purpose: </strong>The phenomenon of avoidable care transitions has received increasing attention over the last decades due to its frequency and associated burden for the patients and the healthcare system. A number of assessment tools to identify avoidable transitions have been designed and implemented. The selection of the most appropriate tool appears to be challenging and time-consuming. This systematic review aimed to identify and comprehensively describe the assessment tools that can support stakeholders´ care transition decisions on older adults.</p><p><strong>Methods: </strong>This study was conducted as part of the TRANS-SENIOR research network. A systematic search was conducted in MEDLINE via PubMed, CINAHL, and CENTRAL. No restrictions regarding publication date and language were applied.</p><p><strong>Results: </strong>The search in three electronic databases revealed 1266 references and screening for eligibility resulted in 58 articles for inclusion. A total of 48 assessment tools were identified covering different concepts, judgement processes, and transition destinations. We found variation in the comprehensiveness of the tools with regard to dimensions used in the judgement process.</p><p><strong>Conclusion: </strong>All tools are not comprehensive with respect to the dimensions covered, as they address only one or a few perspectives. Although assessment tools can be useful in clinical practice, it is worth it to bear in mind that they are meant to support decision-making and supplement the care professional´s judgement, instead of replacing it. Our review might guide clinicians and researchers in choosing the right tool for identification of avoidable care transitions, and thus support informed decision-making.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"1587-1601"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632047/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between medication use and health-related quality of life in multimorbid older patients with polypharmacy.","authors":"Charlotte Falke, Fatma Karapinar, Marcel Bouvy, Mariëlle Emmelot, Svetlana Belitser, Benoit Boland, Denis O'Mahony, Kevin D Murphy, Moa Haller, Paola Salari, Matthias Schwenkglenks, Nicolas Rodondi, Toine Egberts, Wilma Knol","doi":"10.1007/s41999-024-01036-4","DOIUrl":"10.1007/s41999-024-01036-4","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the association between medication use-related factors and health-related quality of life (HRQoL) in older hospitalised multimorbid patients with polypharmacy.</p><p><strong>Methods: </strong>This cross-sectional study used the intervention arm data of the OPERAM trial (hospitalised patients ≥ 70 years with polypharmacy). HRQoL was assessed using the visual analogue scale (EQ-VAS) and the EQ-5D index score of the EuroQol questionnaire (EQ-5D-5L). Lower or higher EQ-VAS/EQ-5D was based on the median of the study population. Medication use-related factors included hyperpolypharmacy (≥ 10 medications), anticholinergic and sedative burden, appropriateness of medication (STOPP/START criteria), high-risk medication for hospital (re)admission, medication complexity and adherence. Multivariable logistic regression analysis was used to assess the association between medication use-related factors and HRQoL.</p><p><strong>Results: </strong>A total of 955 patients were included (mean age 79 years, 46% female, median EQ-VAS of 60, median EQ-5D of 0.60). Opioids use was associated with lower EQ-5D and EQ-VAS (aOR EQ-5D: 2.10; 95% CI 1.34-3.32, EQ-VAS: 1.59; 1.11-2.30). Hyperpolypharmacy (aOR 1.37; 1.05-1.80), antibiotics (aOR 1.64; 1.01-2.68) and high medication complexity (aOR 1.53; 1.10-2.15) were associated with lower EQ-VAS. A high anticholinergic and sedative burden (aOR 1.73; 1.11-2.69), presence of multiple prescribing omissions (aOR 1.94; 1.19-3.17) and benzodiazepine use (aOR 2.01; 1.22-3.35) were associated with lower EQ-5D. Especially in hyperpolypharmacy patients, high anticholinergic and sedative burden and medication complexity were associated with a lower HRQoL.</p><p><strong>Conclusion: </strong>Several medication use-related factors are significantly associated with a lower HRQoL in hospitalised older patients. Medication complexity is a novel factor, which should be considered when evaluating medication use of older patients with hyperpolypharmacy.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"1713-1723"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142005687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive geriatric assessment, and related interventions, to improve outcomes for older patients undergoing transcatheter aortic valve implantation (TAVI): a systematic review.","authors":"Katherine Chin, Rosalind Jones, Eleni Lester, Alice Hegarty, Lieze Thielemans, Rebekah Schiff","doi":"10.1007/s41999-024-01035-5","DOIUrl":"10.1007/s41999-024-01035-5","url":null,"abstract":"<p><strong>Introduction: </strong>Transcatheter aortic valve implantation (TAVI) is a treatment for people with severe symptomatic aortic stenosis, particularly those living with frailty. Increasing frailty is associated with poorer outcomes post-TAVI. Comprehensive Geriatric Assessment (CGA) has been shown in other settings to improve outcomes in those with frailty, including perioperatively. This systematic review aims to determine whether CGA, or interventions targeting its components, improves outcomes for older people undergoing TAVI.</p><p><strong>Methods: </strong>EMBASE, MEDLINE, CINAHL and Cochrane CENTRAL were searched on 09/01/23 and then the search was rerun on the 16/04/24. The review was registered on PROSPERO (CRD42022299955). Included studies had to evaluate either CGA, or a single- or multi-domain intervention targeting components of CGA, in those aged ≥ 65.</p><p><strong>Results: </strong>From 4091 papers, 24 met the inclusion criteria. Two studies assessed CGA pre-TAVI and reported mixed improvements in functional independence but no change in length of stay or post-operative delirium, although both studies had a serious risk of bias. Fifteen papers described an exercise-based intervention, and 1 paper detailed a Cognitive Behavioural Therapy-based intervention. Seven studies evaluated a multi-component intervention. There were conflicting results reported for the multi-component and single-component interventions. All studies had at least a moderate risk of bias.</p><p><strong>Conclusion(s): </strong>There is a lack of evidence to determine whether CGA, or related interventions, improve outcomes for older adults undergoing-TAVI. The evidence for perioperative CGA, and the results of this review, support the need for well-designed trials evaluating whether CGA improves outcomes post-TAVI for older adults living with frailty.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"1615-1630"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631815/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142330775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Artificial Intelligence ageist?","authors":"Yanira Aranda Rubio, Juan José Baztán Cortés, Fernando Canillas Del Rey","doi":"10.1007/s41999-024-01070-2","DOIUrl":"10.1007/s41999-024-01070-2","url":null,"abstract":"<p><strong>Introduction: </strong>Generative Artificial Intelligence (AI) is a technological innovation with wide applicability in daily life, which could help elderly people. However, it raises potential conflicts, such as biases, omissions and errors.</p><p><strong>Methods: </strong>Descriptive study through the negative stereotypes towards aging questionnaire (CENVE) conducted on chatbots ChatGPT, Gemini, Perplexity, YOUChat, and Copilot was conducted.</p><p><strong>Results: </strong>Of the chatbots studied, three were above 50% in responses with negative stereotypes, Copilot with high ageism level results, followed by Perplexity. In the health section, Copilot was the chatbot with the most negative connotations regarding old age (13 out of 20 points). In the personality section, Copilot scored 14 out of 20, followed by YOUChat.</p><p><strong>Conclusion: </strong>The Copilot chatbot responded to the statements more ageistically than the other platforms. These results highlight the importance of addressing any potential biases in AI to ensure that the responses provided are fair and respectful for all potential users.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"1957-1960"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142330788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Averting older adults' memory function decline via meaningful activities: a follow-up longitudinal study.","authors":"Shoma Akaida, Takayuki Tabira, Mana Tateishi, Daijo Shiratsuchi, Suguru Shimokihara, Ryota Kuratsu, Yoshihiko Akasaki, Yuma Hidaka, Hyuma Makizako","doi":"10.1007/s41999-024-01044-4","DOIUrl":"10.1007/s41999-024-01044-4","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of the study was to investigate the effects of satisfaction with meaningful activities and their performance on the memory function among community-dwelling older adults 3 years later.</p><p><strong>Methods: </strong>A longitudinal analysis was conducted on 288 community-dwelling older adults aged 65 years and more who had completed the survey in 2019 and 2022 as participants in the Tarumizu Study. Meaningful activities were assessed in 2019 using the Aid for Decision-Making in Occupation Choice for activities. Satisfaction with and performance of meaningful activities were assessed, and the bottom 25% were classified into two groups: low satisfaction and low performance. Memory function was assessed using the National Center for Geriatrics and Gerontology-Functional Assessment Tool in 2019 and 2022. Changes in memory function over 3 years were analyzed by satisfaction and performance of meaningful activities.</p><p><strong>Results: </strong>Two-way analysis of variance with group (satisfaction with and performance of meaningful activities) and time (2019 and 2022) as factors showed no statistically significant group-time interaction for memory in the satisfaction with meaningful activities group (F = 1.4, p = 0.24). Meanwhile, a statistically significant group-time interaction was observed for memory in the meaningful activity performance group, indicating that high performance of meaningful activities may play a protective role against memory decline (F = 7.4, p = 0.007).</p><p><strong>Conclusion: </strong>Higher performance of meaningful activities may protect against age-related changes in memory. A careful assessment of meaningful activities, and engagement that enhances performance may be useful in designing health support against memory decline.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"1793-1801"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of the SARC-F, SARC-CalF, and calf circumference for sarcopenia case finding in community-dwelling older adults.","authors":"Hanna Kerminen, Satu Jyväkorpi, Annele Urtamo, Heini Huhtala, Hanna Öhman, Riccardo Calvani, Emanuele Marzetti, Kaisu Pitkälä, Timo Strandberg","doi":"10.1007/s41999-024-01060-4","DOIUrl":"10.1007/s41999-024-01060-4","url":null,"abstract":"<p><strong>Purpose: </strong>We compared the performance of SARC-F, SARC-CalF, calf circumference (CC), and body mass index (BMI)-adjusted CC for sarcopenia case-finding in community-dwelling older adults.</p><p><strong>Methods: </strong>Data of Finnish participants (women/men n = 192/36, mean age (SD) of 76.9 (4.8) years) recruited in the SPRINTT trial (NCT02582138) were used. Sarcopenia was determined as a combination of low muscle function (chair-stand-test) and low appendicular lean mass (ALM) detected by whole-body dual-energy X-ray absorptiometry. Associations of case-finding tools with sarcopenia were analysed using ROC curves and logistic regression.</p><p><strong>Results: </strong>The rates of probable and confirmed sarcopenia were 95% and 18% in women and 94% and 36% in men, respectively. Performance of CC for sarcopenia (women AUC 0.85 [95% CI 0.78-0.92]/ men 0.85 [95% CI 0.71-1.0]) was superior to that of other tools; (AUC in women/men for SARC-F was 0.57/0.50, for SARC-CalF 0.76/0.79, and for BMI-adjusted CC 0.68/0.66). The best performance was found for a CC cut-off point of ≤ 34 cm in women with sensitivity/specificity 82.4/75.3% and ≤ 36 cm in men with sensitivity/specificity 76.9/87.0%. For each cm decrease in CC, adjusted for age and BMI, there was a 30% increase in the odds of sarcopenia in women (OR 1.30, 95% CI 1.09─1.56). Although there was a similar pattern in men, the results did not reach statistical significance (OR 1.34, 95% CI 0.84- 2.14).</p><p><strong>Conclusions: </strong>CC was superior to other tools for sarcopenia case-finding. The best performance was found for a CC cut-off point of ≤ 34 cm in women and ≤ 36 cm in men.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"1817-1826"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: The association between medication use and health-related quality of life in multimorbid older patients with polypharmacy.","authors":"Charlotte Falke, Fatma Karapinar, Marcel Bouvy, Mariëlle Emmelot, Svetlana Belitser, Benoit Boland, Denis O'Mahony, Kevin D Murphy, Moa Haller, Paola Salari, Matthias Schwenkglenks, Nicolas Rodondi, Toine Egberts, Wilma Knol","doi":"10.1007/s41999-024-01072-0","DOIUrl":"10.1007/s41999-024-01072-0","url":null,"abstract":"","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"1725-1730"},"PeriodicalIF":3.5,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11631812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}