European Geriatric Medicine最新文献

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Predictive factors of concern about falling after hospital discharge among older adults with fragility hip fractures: a prospective cohort study. 老年人脆性髋部骨折出院后跌倒的预测因素:一项前瞻性队列研究
IF 3.5 3区 医学
European Geriatric Medicine Pub Date : 2025-03-25 DOI: 10.1007/s41999-025-01188-x
Suphawita Pliannuom, Phichayut Phinyo, Nida Buawangpong, Nopakoon Nantsupawat, Pichitchai Atthakomol, Tanawat Vaseenon, Nitchanant Kitcharanant, Peerasak Lerttrakarnnon, Kanokporn Pinyopornpanish
{"title":"Predictive factors of concern about falling after hospital discharge among older adults with fragility hip fractures: a prospective cohort study.","authors":"Suphawita Pliannuom, Phichayut Phinyo, Nida Buawangpong, Nopakoon Nantsupawat, Pichitchai Atthakomol, Tanawat Vaseenon, Nitchanant Kitcharanant, Peerasak Lerttrakarnnon, Kanokporn Pinyopornpanish","doi":"10.1007/s41999-025-01188-x","DOIUrl":"https://doi.org/10.1007/s41999-025-01188-x","url":null,"abstract":"<p><strong>Purpose: </strong>Concern about falling [CaF] is common among older adults, particularly after fragility hip fracture. This condition is associated with adverse health outcomes and a reduced quality of life. The aim of this study is to explore predictors of CaF among older patients with fragility hip fractures 2 weeks after hospital discharge.</p><p><strong>Methods: </strong>A prospective observational cohort study was conducted at a Tertiary Care Hospital in Thailand. Participants were patients aged 60 years and above who had fragility hip fractures and were admitted to the hospital from March 2023 to March 2024. CaF was assessed using the short Falls Efficacy Scale-International 2 weeks after hospital discharge. Predictors examined pre-fall characteristics, fall-related data, surgery-related data, and postoperative data. In the full model approach, the multivariable Gaussian regression was employed to identify predictive factors.</p><p><strong>Results: </strong>Of the 165 patients included in the study (mean age 78.76 ± 8.72 years), 79.39% were female. In the full model approach, pre-fracture activities of daily living (ADL) < 20 (adjusted mean difference [aMD] 3.44, 95% CI 1.04-5.85, p = 0.005) and shorter in-hospital duration of walking training (aMD - 0.66, 95% CI - 1.10 to - 0.22, p = 0.004) were identified as predictors of CaF at 2 weeks after hospital discharge.</p><p><strong>Conclusions: </strong>The findings of this study emphasize the importance of assessing pre-fracture functional status and the shorter duration of in-hospital walking training as key predictors of CaF in older adults with fragility hip fractures. Enhancing functional capacity and extending the duration of walking training during hospitalization are crucial steps in reducing CaF in this population.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex differences in sarcopenia prevalence and muscle-related outcomes among post-stroke inpatients. 卒中后住院患者肌肉减少症患病率和肌肉相关结局的性别差异
IF 3.5 3区 医学
European Geriatric Medicine Pub Date : 2025-03-23 DOI: 10.1007/s41999-025-01186-z
Yoshihiro Yoshimura, Hidetaka Wakabayashi, Fumihiko Nagano, Ayaka Matsumoto, Sayuri Shimazu, Ai Shiraishi, Yoshifumi Kido, Takahiro Bise, Takenori Hamada, Kouki Yoneda
{"title":"Sex differences in sarcopenia prevalence and muscle-related outcomes among post-stroke inpatients.","authors":"Yoshihiro Yoshimura, Hidetaka Wakabayashi, Fumihiko Nagano, Ayaka Matsumoto, Sayuri Shimazu, Ai Shiraishi, Yoshifumi Kido, Takahiro Bise, Takenori Hamada, Kouki Yoneda","doi":"10.1007/s41999-025-01186-z","DOIUrl":"https://doi.org/10.1007/s41999-025-01186-z","url":null,"abstract":"<p><strong>Background: </strong>Sex differences in sarcopenia prevalence and recovery patterns among post-stroke patients remain poorly understood. This study aimed to investigate sex differences in sarcopenia prevalence, improvement rates, and changes in muscle-related indices among post-stroke patients in rehabilitation settings.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted at a post-acute rehabilitation hospital. Sarcopenia was diagnosed using the Asian Working Group for Sarcopenia 2019 criteria. The primary outcomes were sarcopenia status and muscle-related indices (handgrip strength and skeletal muscle mass index) at discharge. Propensity score-adjusted logistic regression analysis was performed to examine the association between sex and non-sarcopenia at discharge.</p><p><strong>Results: </strong>A total of 598 patients (274 women) with a mean age of 71.6 years were analyzed. Women showed higher sarcopenia prevalence at admission compared to men (47.4% vs 34.2%, p = 0.001). After adjusting for confounders, male sex was positively associated with non-sarcopenia at discharge (OR 1.046, 95% CI 1.009-1.104, p < 0.001) and greater improvements in handgrip strength (B = 1.93, p = 0.031) and skeletal muscle mass index (B = 0.322, p = 0.019).</p><p><strong>Conclusion: </strong>This study revealed significant sex differences in sarcopenia among post-stroke rehabilitation patients. While women showed higher sarcopenia prevalence at admission, men demonstrated better improvements in muscle-related outcomes.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of geriatric syndrome burden on healthcare services utilization and mortality among community-dwelling older adults: is it still too late to do something? 老年综合征负担对社区居住老年人卫生保健服务利用和死亡率的影响:现在采取行动是否为时已晚?
IF 3.5 3区 医学
European Geriatric Medicine Pub Date : 2025-03-22 DOI: 10.1007/s41999-025-01189-w
Bilal Katipoglu, Suleyman Emre Kocyigit
{"title":"Impact of geriatric syndrome burden on healthcare services utilization and mortality among community-dwelling older adults: is it still too late to do something?","authors":"Bilal Katipoglu, Suleyman Emre Kocyigit","doi":"10.1007/s41999-025-01189-w","DOIUrl":"https://doi.org/10.1007/s41999-025-01189-w","url":null,"abstract":"<p><strong>Purpose: </strong>The increasing longevity of the population emphasizes the need for a deeper understanding of geriatric syndromes and their implications for healthcare usage and mortality among older adults. This study aimed to identify risk factors associated with healthcare service utilization and mortality of community-dwelling adults aged 80 and older in YASAM project.</p><p><strong>Methods: </strong>This prospective cohort study was part of the HEAT-YASAM trial, which focused on the community-based integrated healthy aging program for individuals aged 80 years and older in Balıkesir, Türkiye. The burden of geriatric syndromes was assessed based on a comprehensive evaluation at least two domains of the nutrition, cognitive, physcological and locomotor capacities. The study outcome was healthcare services utilization (inpatient, outpatient, emergency admission) and all-cause mortality data obtained during follow-up period (9 months).</p><p><strong>Results: </strong>The cohort consisted of 5018 participants with a mean age of 85.8 years, predominantly female (53.1%). On the multivariable analysis, geriatric syndrome burden and Deyo Charlson Comorbidity index (D-CCI) score significant on independent predictors of 9-month mortality (p = 0.01). Higher geriatric syndrome burden was linked to an approximately 10% lower risk for outpatient admissions (p = 0.01) and every point increase in the D-CCI score was associated with a 1.3-fold increased risk of utilizing outpatient services (p = 0.01). For multimorbidity, every point increase corresponded to a 2.6-fold higher risk of inpatient admissions (p = 0.01) and a 1.2-fold higher risk of emergency admissions (p = 0.01).</p><p><strong>Conclusions: </strong>This study demonstrate that a geriatric syndrome burden and multimorbidity has a significant impact on healthcare utilization and mortality in adults aged 80 years and older. Integrated comprehensive, coordinated, and patient-centered care models for this population facing multiple geriatric syndromes could positively impact the healthcare system.</p><p><strong>Trial registration: </strong>The trial was prospectively registered at ClinicalTrials.gov. Identifier: NCT05993572 Registered on 15 July 2023.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
eHealth in geriatric rehabilitation: an international consensus study. 老年康复中的电子健康:一项国际共识研究。
IF 3.5 3区 医学
European Geriatric Medicine Pub Date : 2025-03-21 DOI: 10.1007/s41999-025-01170-7
Jules J M Kraaijkamp, Anke Persoon, Niels H Chavannes, Wilco P Achterberg, Mohamed-Amine Choukou, Frances Dockery, Hyub Kim, Laura M Pérez, José E Pompeu, Eva Topinkova, Mark A Vassallo, Andrea B Maier, Clemens Becker, Yoshiaki Amagasa, Marije S Holstege, Jolanda van Haastregt, Eléonore F van Dam van Isselt
{"title":"eHealth in geriatric rehabilitation: an international consensus study.","authors":"Jules J M Kraaijkamp, Anke Persoon, Niels H Chavannes, Wilco P Achterberg, Mohamed-Amine Choukou, Frances Dockery, Hyub Kim, Laura M Pérez, José E Pompeu, Eva Topinkova, Mark A Vassallo, Andrea B Maier, Clemens Becker, Yoshiaki Amagasa, Marije S Holstege, Jolanda van Haastregt, Eléonore F van Dam van Isselt","doi":"10.1007/s41999-025-01170-7","DOIUrl":"https://doi.org/10.1007/s41999-025-01170-7","url":null,"abstract":"<p><strong>Purpose: </strong>Current evidence on the use of eHealth in geriatric rehabilitation is limited. This aim of this study was to achieve international consensus on three key eHealth-related topics in geriatric rehabilitation: the use, domains, and scientific evaluation of eHealth. Additionally, we developed a model that provides insight into the use of eHealth in geriatric rehabilitation.</p><p><strong>Methods: </strong>An international, two-round Delphi study was conducted. Two models served as a framework for the initial statement draft, with a total of 28 statements based on our systematic review results, an international survey, and expert opinion. Eligible healthcare professionals working in geriatric rehabilitation facilities were recruited across 10 countries.</p><p><strong>Results: </strong>Eighty healthcare professionals participated in round one and 47 in round two. In the first round, consensus was obtained for 20 of the 28 statements (71%). Prior to round two, four statements were revised, two statements were combined, and one statement was removed. In round two, consensus was obtained on six statements, bringing the total to 26: three related to the use of eHealth, five to the domains of eHealth, and 18 related to the scientific evaluation of eHealth.</p><p><strong>Conclusion: </strong>International consensus has been reached on the use, domains, and scientific evaluation of eHealth in geriatric rehabilitation. This first step in generating reliable knowledge and understandable information will help promote a consistent approach to the development, implementation, and scientific evaluation of eHealth in geriatric rehabilitation.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The perceptions of European geriatricians on the co-occurrence and links between dementia, delirium and frailty. 欧洲老年病学家对痴呆、谵妄和虚弱之间的共同发生和联系的看法。
IF 3.5 3区 医学
European Geriatric Medicine Pub Date : 2025-03-15 DOI: 10.1007/s41999-025-01173-4
Mary Faherty, Catriona Curtin, Giuseppe Bellelli, Enrico Brunetti, Mario Bo, Alessandro Morandi, Antonio Cherubini, Massimiliano Fedecostante, Maria Cristina Ferrara, Alessandra Coin, Susan D Shenkin, Pinar Soysal, Suzanne Timmons
{"title":"The perceptions of European geriatricians on the co-occurrence and links between dementia, delirium and frailty.","authors":"Mary Faherty, Catriona Curtin, Giuseppe Bellelli, Enrico Brunetti, Mario Bo, Alessandro Morandi, Antonio Cherubini, Massimiliano Fedecostante, Maria Cristina Ferrara, Alessandra Coin, Susan D Shenkin, Pinar Soysal, Suzanne Timmons","doi":"10.1007/s41999-025-01173-4","DOIUrl":"https://doi.org/10.1007/s41999-025-01173-4","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to explore the perceptions of geriatricians and experienced geriatric trainees in Europe of the complex relationship between dementia, delirium and frailty, including their relative prevalence, overlaps and causality.</p><p><strong>Methods: </strong>An online anonymous survey was administered across 30 European countries, via the mailing list of the European Geriatric Medicine Society (EuGMS), national member groups and the authors' professional networks. Questions were framed in the context of recently hospitalised 80-year-old patients.</p><p><strong>Results: </strong>Within the 440 included surveys, respondents particularly over-estimated frailty prevalence in older hospitalised patients, with two-thirds choosing between 41 and 80% prevalence, when the literature suggests only 23-46%, but paradoxically underestimated the frequency of frailty in people with delirium (more than three quarters of responses across 21-80%; literature suggests 71-93%). Severe dementia and previous delirium were correctly considered the strongest risks for future inpatient delirium. However, many considered pre-frailty a moderate (44%) or even strong (19%) risk for future delirium, while a minority considered severe dementia a low risk. Respondents viewed delirium superimposed on dementia (DSD) as having the strongest influence on in-hospital mortality and discharge to residential care, dementia as having the strongest influence on future residential care admission, and frailty as the condition most strongly influencing future mortality.</p><p><strong>Conclusion: </strong>Geriatricians and experienced geriatric trainees across Europe gave varied responses to questions about delirium, dementia and frailty prevalence, co-occurrence and consequences. This indicates a need for the performance and wide dissemination of robust, prospective research examining all three conditions in older hospital cohorts. We suggest a merging of selective delirium-frailty and dementia-delirium interests to the dementia-delirium-frailty triumvirate.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The perspectives on advance care planning of older people with psychotic illnesses and their carers. 老年精神病患者及其照护者预先照护计划的观点。
IF 3.5 3区 医学
European Geriatric Medicine Pub Date : 2025-03-14 DOI: 10.1007/s41999-025-01161-8
Anne Wand, Aspasia Karageorge, Yucheng Zeng, Roisin Browne, Meg Sands, Daniella Kanareck, Vasi Naganathan, Anne Meller, Carolyn Smith, Carmelle Peisah
{"title":"The perspectives on advance care planning of older people with psychotic illnesses and their carers.","authors":"Anne Wand, Aspasia Karageorge, Yucheng Zeng, Roisin Browne, Meg Sands, Daniella Kanareck, Vasi Naganathan, Anne Meller, Carolyn Smith, Carmelle Peisah","doi":"10.1007/s41999-025-01161-8","DOIUrl":"https://doi.org/10.1007/s41999-025-01161-8","url":null,"abstract":"<p><strong>Purpose: </strong>To examine the attitudes, experiences, and perceived facilitators and barriers to Advance Care Planning (ACP), of older people with schizophrenia and other psychotic illness and their carers.</p><p><strong>Methods: </strong>Older people with a psychotic illness and carers were recruited from public mental health services in Sydney, Australia. Semi-structured interviews to explore attitudes, experiences, and perceived barriers and facilitators to ACP were conducted by an external clinician. Consumers' medical, psychiatric and drug health diagnoses were recorded and they completed cognitive and symptom rating scales. Reflexive thematic analysis was used to analyse the transcripts of interviews, within an interpretive description framework.</p><p><strong>Results: </strong>Thematic saturation was achieved with 12 consumers and 5 carers. Emergent themes from consumer interviews were (i) 'What is ACP?'; (ii) 'I have not done ACP because…..'; (iii) 'I want to do ACP'; (iv) 'If I was to do ACP I would need..'; and (v) 'Mental health clinicians have the skills to help me with ACP'. Carer themes included (i) 'We do not participate in ACP', (ii) 'I want to participate in ACP', and (iii) 'Key clinician skills are needed'. There was convergence of themes from both groups.</p><p><strong>Conclusion: </strong>This study demonstrates that older people with a psychotic illness can express views regarding ACP, despite ongoing symptoms of psychosis, cognitive impairment and mild-moderate severity of illness. The emergent themes highlight opportunities to intervene to overcome barriers to ACP, including education for both participant groups and clinicians, practical considerations and the need for all to collaborate, including with primary care.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of the nurse directed frailty assessment tool, to identify patients at risk of emergency department visits, hospitalisation, and 1-year all-cause mortality. 验证护士指导的衰弱评估工具,以确定有急诊就诊、住院和1年全因死亡率风险的患者。
IF 3.5 3区 医学
European Geriatric Medicine Pub Date : 2025-03-14 DOI: 10.1007/s41999-025-01182-3
P H Drop, C van Ham, A C M Mulder, P A Veeken-Dijkstra, J O Daal, L A R Zwart
{"title":"Validation of the nurse directed frailty assessment tool, to identify patients at risk of emergency department visits, hospitalisation, and 1-year all-cause mortality.","authors":"P H Drop, C van Ham, A C M Mulder, P A Veeken-Dijkstra, J O Daal, L A R Zwart","doi":"10.1007/s41999-025-01182-3","DOIUrl":"https://doi.org/10.1007/s41999-025-01182-3","url":null,"abstract":"<p><strong>Methods: </strong>This is a validation study of a new frailty assessment that can be administered by outpatient care nurses. The nurse directed frailty assessment (NDFA) encompasses the medical, psychological, social, and functional domain, based on standard care, and can be performed without any specialised equipment. Performance of the NDFA is compared to a comprehensive geriatric assessment (CGA)-based frailty index (FI), with generalised linear model with reporting of hazard ratios (HR) and 95% confidence intervals (95% CI). The best cutoff value for the NDFA was assessed by Youden index and the area under the receiver operator curve (ROC).</p><p><strong>Results: </strong>Within 1 year, 15 patients (5%) died, 57 (18%) had an unplanned hospital admission, and 83 (26%) visited the emergency department (ED). Based on the Youden index and ROC curve, the best cutoff value for the NDFA was 4 points. With a binary logistic regression model, an HR of 3.59 (95% CI 1.16-11.15, p < 0.001) was found for mortality. In the general mixed model with Poisson logistic regression, an HR of 1.78 (95% CI 1.06-2.97, p 0.028) was found for unplanned hospital and an HR of 1.87 (95% CI 1.25-2.78, p 0.002) was found for ED visits. The HR and 95% CI of the FI were similar for all three outcome measures.</p><p><strong>Conclusions: </strong>The NDFA identifies patients at risk for hospitalisation, emergency department visits, and mortality within 12 months equally well as the FI. Further research is necessary to determine the effectiveness of the NDFA in other settings than the geriatric medicine outpatient population.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychomotor disadaptation syndrome: a scoping review. 精神运动性适应障碍综合征:范围综述。
IF 3.5 3区 医学
European Geriatric Medicine Pub Date : 2025-03-13 DOI: 10.1007/s41999-025-01176-1
Antonella Merendino, France Mourey, Thomas Renoncourt, Sofia Da Silva, Mélanie Dipanda, Fabrice Larosa, Alain Putot, Patrick Manckoundia
{"title":"Psychomotor disadaptation syndrome: a scoping review.","authors":"Antonella Merendino, France Mourey, Thomas Renoncourt, Sofia Da Silva, Mélanie Dipanda, Fabrice Larosa, Alain Putot, Patrick Manckoundia","doi":"10.1007/s41999-025-01176-1","DOIUrl":"https://doi.org/10.1007/s41999-025-01176-1","url":null,"abstract":"<p><strong>Background: </strong>Clinical features of psychomotor disadaptation syndrome (PDS) include posture, gait, psycho-behavioral, and neurological disorders, which increase the risk of falling. Psychomotor regression syndrome, described in 1986, was renamed PDS following improvements in its pathophysiological understanding, including the preeminent role of subcortical-frontal lesions. Because frailty in aging contributes to the appearance of PDS, the geriatric professionals need to be aware of its existence.</p><p><strong>Purpose: </strong>This article aims to provide a scoping review on PDS. Moreover, we searched for epidemiological studies and assessed whether or not all the aspects of PDS are recognized.</p><p><strong>Methods: </strong>The studies were retrieved from three electronic databases (PubMed, Science Direct, and Google Scholar) using these terms: psychomotor disadaptation syndrome, psychomotor regression syndrome, frontal-sub-cortical dysfunction syndrome, backward disequilibrium, retropulsion, post-fall syndrome, reactional hypertonia, axial akinesia, and older adults.</p><p><strong>Results: </strong>Out of 456 shortlisted articles, 45 met the inclusion criteria. Our results show that PDS is poorly known, especially outside of France, which had the largest number of published studies on this syndrome. Abroad, only three aspects have been described (post-fall syndrome, retropulsion, and fear of falling). Often, they are not recognized as belonging to a real syndrome, but rather an association of signs. Post-fall syndrome, found in 14 studies, is the best known and most studied aspect of PDS. There were no epidemiological studies.</p><p><strong>Conclusion: </strong>With the increasing number of frail older adults, there will be an inevitable growth in the incidence of PDS. Raising awareness about PDS among medical and paramedical geriatrics professionals is essential.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fndc5/irisin mediates the benefits of aerobic exercise intervention on aging-associated sarcopenia in mice. Fndc5/鸢尾素介导有氧运动干预对小鼠衰老相关肌肉减少症的益处。
IF 3.5 3区 医学
European Geriatric Medicine Pub Date : 2025-03-13 DOI: 10.1007/s41999-025-01181-4
Yuxia Ma, Yi Liu, Jiachuang Zheng, Zhixia Zheng, Jingjing Li
{"title":"Fndc5/irisin mediates the benefits of aerobic exercise intervention on aging-associated sarcopenia in mice.","authors":"Yuxia Ma, Yi Liu, Jiachuang Zheng, Zhixia Zheng, Jingjing Li","doi":"10.1007/s41999-025-01181-4","DOIUrl":"https://doi.org/10.1007/s41999-025-01181-4","url":null,"abstract":"<p><strong>Methods: </strong>In this study, 24-month-old (aged) mice were used as a naturally occurring model of aging-associated sarcopenia, while 2-month-old (young) mice served as the normal control. Six weeks of treadmill training was employed as an aerobic exercise intervention. The mRNA and protein levels of fibronectin type III domain-containing protein 5 (Fndc5/irisin), MuRF1, and Atrogin-1 in gastrocnemius muscles were analyzed using qRT-PCR and Western blot. Oxidative stress was assessed using relevant detection kits. Skeletal muscle function was evaluated through the four-paw hanging test, rotarod test, grip strength assay, and measurements of quadriceps, tibialis anterior, and gastrocnemius muscle mass.</p><p><strong>Results: </strong>Aerobic exercise interventions enhanced skeletal muscle function by increasing hanging time, maximum speed, grip strength, and increased quadriceps, gastrocnemius, and tibialis anterior muscle mass. On the other hand, aerobic exercise reduced MuRF1 and Atrogin-1 expression in the gastrocnemius muscles of sarcopenia mice, along with lower malondialdehyde levels, and higher superoxide dismutase activity, T-ATPase, and glutathione peroxidase activity. A decline in Fndc5/irisin expression was further detected in the gastrocnemius muscles with aging. In Fndc5-knockout aged mice, aerobic exercise failed to improve skeletal muscle function compared to wild-type aged mice, as evaluated by hanging time, grip strength, maximum speed, and quadriceps, gastrocnemius, and tibialis anterior muscle mass, further validating the involvement of Fndc5 in the improvement of aging-associated sarcopenia.</p><p><strong>Conclusion: </strong>Aerobic exercise improves aging-associated sarcopenia in mice, with Fndc5/irisin playing a role in this process.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of psychiatric vulnerability and neurocognitive disorders in nursing homes: impact on care levels. 疗养院中精神脆弱性和神经认知障碍的患病率:对护理水平的影响。
IF 3.5 3区 医学
European Geriatric Medicine Pub Date : 2025-03-13 DOI: 10.1007/s41999-025-01179-y
Katrin Gillis, Hanne Van Herbruggen, Marianne De Witte, Lore Baeck, Melanie Elisabeth Benoit Van Bogaert, Hilde Lahaye, Linda van Diermen
{"title":"Prevalence of psychiatric vulnerability and neurocognitive disorders in nursing homes: impact on care levels.","authors":"Katrin Gillis, Hanne Van Herbruggen, Marianne De Witte, Lore Baeck, Melanie Elisabeth Benoit Van Bogaert, Hilde Lahaye, Linda van Diermen","doi":"10.1007/s41999-025-01179-y","DOIUrl":"https://doi.org/10.1007/s41999-025-01179-y","url":null,"abstract":"<p><strong>Purpose: </strong>There is an increasing number of residents with more complex needs in nursing homes. Due to the deinstitutionalisation of mental health care, more individuals with psychiatric vulnerabilities are being referred to nursing homes. The aim of this study is to gain insight into the prevalence of psychiatric vulnerability in Belgian nursing homes and its impact on care levels.</p><p><strong>Methods: </strong>After screening 3238 patient files of residents in twenty-four Belgian nursing homes, informed consent was obtained from 1155 of the 1608 residents or their legal representatives with a neurocognitive and/or psychiatric diagnosis. Residents were classified into three groups: residents with only a psychiatric diagnosis, with only a neurocognitive diagnosis, and both a psychiatric and neurocognitive diagnosis. The Health of Nations Outcome Scale 65 + was used to assess residents' behaviour, limitations, symptoms, and functioning.</p><p><strong>Results: </strong>Of all residents, 17.5% had a lifetime psychiatric diagnosis and 41.8% had a neurocognitive disorder. Most prevalent were depressive disorder (8.2%) and Alzheimer's disease (19.3%). Scores for behavioural problems (1.4 and 1.4 versus 0.9, p < 0.0001) and symptoms (5.5 and 5.1 versus 4.4, p < 0,0001) were higher in residents with only a psychiatric or both diagnoses compared to those with only neurocognitive disorders. Conversely, scores for limitations were higher in residents with only a neurocognitive disorder (3.6 versus 2.2 and 3.1, p < 0.0001).</p><p><strong>Conclusion: </strong>With almost 1 in 5 nursing home residents having a psychiatric vulnerability with higher levels of symptoms and behavioural problems, more attention towards improving nursing home caregivers' competence in psychiatric care is recommended.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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