European Geriatric Medicine最新文献

{"title":"Physical and oral frailty: two edges of Damocles' sword.","authors":"Jerzy Gąsowski, Karolina Piotrowicz","doi":"10.1007/s41999-024-01118-3","DOIUrl":"10.1007/s41999-024-01118-3","url":null,"abstract":"","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"163-164"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The 1-year trajectory of older patients transferred from an intensive care unit to an acute geriatric unit.","authors":"A Charpentier, M Garnier, G Deschasse, W Vandenberghe, J B Beuscart, F Visade","doi":"10.1007/s41999-024-01108-5","DOIUrl":"10.1007/s41999-024-01108-5","url":null,"abstract":"<p><strong>Purpose: </strong>The benefits of intensive care (in terms of the maintenance of functional independence and a reduction in the mortality rate in older patients) are still subject to debate, and the value of geriatric care of older adults discharged from an intensive care unit (ICU) has not been extensively studied. The objective of the present study was to examine the 1-year trajectory of patients transferred from an ICU to an acute geriatric unit (AGU).</p><p><strong>Methods: </strong>We conducted an ambispective, descriptive, single-center study of older adults aged 75 and over from the DAMAGE cohort and having been transferred from an ICU to an AGU. The outcomes (functional independence, according to the Katz Activities of Daily Living (ADL) scale, place of living, and mortality) were documented on discharge from the AGU and 3 and 12 months thereafter.</p><p><strong>Results: </strong>Of the 3,500 older adults in the DAMAGE cohort, 130 patients had been admitted to an ICU and transferred to an AGU. Before hospitalization, the median ADL score was 5 out of 6 (interquartile range [IQR] 4-6), with a majority of people living at home (n = 106, 82%). On discharge from the AGU, 113 patients were alive and had a median ADL score of 4 (IQR [2-5]). Fifty-nine patients (52.2%) were discharged to home. At 3 months and 12 months post-discharge, respectively, 97 (85.8%) and 79 (69.9%) patients were still alive and were functionally independent (median ADL scores: 4.5 (IQR [4; 5.5] and 5 (IQR [4-6])); 75 (66.4%) and 57 (50.4%) were still living at home.</p><p><strong>Conclusion: </strong>Our results show that many older adults transferred from ICU to an AGU maintain their functional independence, which enables them to be discharged to home and remain there for at least the following year. Further research should address the detection of geriatric syndromes at an early stage and the identification of patients who could benefit from the ICU-AGU trajectory.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"363-371"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142733644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mortality for Alzheimer's disease during the COVID-19 pandemic.","authors":"Camilla Mattiuzzi, Giuseppe Lippi","doi":"10.1007/s41999-024-01096-6","DOIUrl":"10.1007/s41999-024-01096-6","url":null,"abstract":"<p><strong>Aim: </strong>Coronavirus disease 2019 (COVID-19) negatively impacts the progression of Alzheimer's disease. The aim of this study was to determine whether mortality from Alzheimer's disease has changed during the COVID-19 pandemic.</p><p><strong>Methods: </strong>We searched the WONDER database, to obtain cumulative and sex-specific age-adjusted death rates of Alzheimer's disease between the years 2018 and 2022.</p><p><strong>Results: </strong>Cumulative age-adjusted mortality rate displayed a peak in 2020, followed by gradual decline thereafter. The data for both sexes mirror that of total population, peaking in 2020, followed by a decline thereafter. The relative increase in age-adjusted mortality for Alzheimer's disease in 2020 compared to 2019 was + 8.7% in the total population, + 6.1% in men and + 10.1% in women.</p><p><strong>Conclusions: </strong>Frail people, such as those with Alzheimer's disease, may be more vulnerable to the risk of dying during an outbreak of infectious disease, paving the way for increased preventive and protective measures in the unfortunate event of the next pandemic.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"379-381"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of structured positive feedback intervention on standing reach ability among older adults admitted to a convalescent rehabilitation ward: a small-sample pilot randomized controlled trial.","authors":"Hiroyuki Uchida, Akina Miki, Akane Ida, Takumi Igusa, Kazuki Hirao","doi":"10.1007/s41999-024-01094-8","DOIUrl":"10.1007/s41999-024-01094-8","url":null,"abstract":"<p><strong>Purpose: </strong>Interventions to improve the standing reach ability of older adults are essential for full functional independence, and structured positive feedback (PF) may be an effective intervention strategy. The purposes of this pilot randomized controlled trial (RCT) are to investigate the preliminary efficacy of structured PF for improving the standing reach ability of older patients admitted to a convalescent rehabilitation ward and evaluate the feasibility of a future full-scale RCT.</p><p><strong>Methods: </strong>Thirty-two eligible older adults (83.3 ± 5.9 years, 23 women) out of 587 potential participants were randomly assigned 1:1 to structured PF (experimental) and conventional rehabilitation (control) groups. Only the experimental group received PF intervention for standing reach ability once every 3 days. Both groups engaged in conventional rehabilitation programs for 2-3 h every day. The primary outcome was change in Functional Reach Test (FRT) performance after 5 weeks of the indicated intervention compared to baseline. Secondary outcomes were change in Short Falls Efficacy Scale International (Short FES-I), a self-reported measure of fear of falling, and Functional Independence Measure (FIM) scores after the 5-week intervention.</p><p><strong>Results: </strong>The estimated difference in mean FRT change (∆) between experimental and control groups was - 4.1 cm (P = 0.07) according to a linear mixed model, supporting the potential efficacy of PF for improving standing reach ability. Further, Hedge's g value was 0.71, consistent with a moderate effect size. However, the estimated mean change in Short FES-I between groups also indicated greater fear of falling in the experimental group (∆ = - 4.5, P = 0.009, g = 1.0). In contrast, the intervention effect on FIM was negligible (∆ = 2.0, P = 0.66, g = - 0.1).</p><p><strong>Conclusions: </strong>These results support the preliminary effectiveness of structured PF for improving the standing reach ability of older adults. A larger-sample RCT is warranted for validation and optimization of the structured PF protocol.</p><p><strong>Trial registration: </strong>The University Hospital Medical Information Network (UMIN) Registered 31 May 2022 (UMIN000047647).</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"325-336"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting neurocognitive decline in older persons living with VIH: a spotlight on the T-CD4 + /CD8 + ratio.","authors":"Sergio Serrano-Villar, Santiago Moreno","doi":"10.1007/s41999-024-01144-1","DOIUrl":"10.1007/s41999-024-01144-1","url":null,"abstract":"","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"315-316"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association between sarcopenic obesity, sarcopenia and functional dependence, malnutrition, and mortality: the phenomenon of obesity paradox in sarcopenic obesity.","authors":"Yuexing Zhou, Chi Sun, Rui Zhao, Chen Dong, Zhifeng Gu, Jianlin Gao","doi":"10.1007/s41999-024-01139-y","DOIUrl":"10.1007/s41999-024-01139-y","url":null,"abstract":"<p><p>The aim of this study is to investigate the association between four phenotypes of sarcopenia/obesity in older individuals and functional disability, malnutrition, and all-cause mortality. This study is a cross-sectional study, survival is 3 years. A total of 487 Chinese older adults were included with 283 (58.1%) females, a median age of 77 (69, 99) years. Sarcopenia was diagnosed according to skeletal muscle mass index, grip strength (GS), 5-time chair stand test, and gait speed test; obesity was diagnosed according to waist circumference, body mass index (BMI), and the percentage of body fat (PBF). Nutritional status was estimated with the Mini Nutritional Assessment short-form (MNA-SF) and functional health status was assessed using the Barthel Index (BI). The binary logistic regression analysis and the multivariate Cox regression analysis were utilized to investigate the association between sarcopenic/obesity phenotype and functional impairment, nutritional deficiency, and all-cause mortality. In the final-adjusted model, compared to patients with non-sarcopenic non-obesity phenotype, sarcopenic obesity is significantly associated with functional dependence (odds ratio [OR]: 3.83, 95% CI 1.47-9.97; P = 0.006), malnutrition (OR: 0.48, 95% CI 0.24-0.99; P = 0.047), and all-cause mortality (hazard ratio[HR]: 2.78, 95% CI 1.57-4.94; P = 0.001); sarcopenia is significantly associated with malnutrition (OR: 2.48, 95% CI 1.09-5.65; P = 0.030), and all-cause mortality (HR:3.06, 95% CI 1.69-5.56; P < 0.001); obesity is significantly associated with malnutrition (OR:0.11, 95% CI 0.05-0.22; P < 0.001). Consequently, it is advisable to incorporate sarcopenia and sarcopenic obesity into the screening and treatment protocols for older adults in the community to effectively mitigate the adverse health consequences.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"89-97"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Survey on current clinical practice in geriatric oncology: the individual experience in five European Cancer Centers.","authors":"M Javier-González, R Boulahssass, L Dal Lago, N M González-Senac, S Nair, M Vetter","doi":"10.1007/s41999-024-01041-7","DOIUrl":"10.1007/s41999-024-01041-7","url":null,"abstract":"<p><strong>Purpose: </strong>To gather information from clinicians on how geriatric oncology models of care have emerged in different European countries and describe current practice in this clinical area.</p><p><strong>Methods: </strong>A semi-structured online interview was performed, exploring aspects related to implementation, perceived quality of care, and professional satisfaction.</p><p><strong>Results: </strong>The centers participating in this interview showed significant differences in terms of resource allocation, team members, components of the comprehensive geriatric assessment (CGA), and CGA-driven interventions. High levels of professional satisfaction were expressed by all participants. This was deemed a consequence of a perception of increased quality in the provision of care and enhanced educational and academic opportunities.</p><p><strong>Conclusion: </strong>Interdisciplinary models of care in geriatric oncology, regardless of implementation details, seem to provide grounds for increased professional satisfaction and perception of better provision of quality of care. These characteristics could support promoting and further developing similar collaborations on a wider scale.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"125-133"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On-site physiotherapy in older emergency department patients following a fall: a randomized controlled trial.","authors":"Jonathan Benhamou, Tanguy Espejo, Henk B Riedel, Thomas Dreher-Hummel, Ana García-Martínez, Barbara Gubler-Gut, Joris Kirchberger, Jan-Arie Overberg, Guido Perrot, Roland Bingisser, Christian H Nickel","doi":"10.1007/s41999-024-01091-x","DOIUrl":"10.1007/s41999-024-01091-x","url":null,"abstract":"<p><strong>Purpose: </strong>Greater fear of falling (FOF) is associated with an increased risk of falling in patients aged 65 and older. This study aims to assess the impact of physiotherapy on FOF in older patients and investigates the feasibility of such an intervention in the emergency department (ED) setting.</p><p><strong>Methods: </strong>All patients aged 65 or older, who presented to the ED of the University Hospital Basel after a fall between January 2022 and June 2023 were screened for inclusion. Participants were assigned to an intervention or control group depending on the randomized presence or absence of a physiotherapist at inclusion. Both groups received the same fall prevention booklet. Physiotherapists instructed and performed exercises with patients in the intervention group. The primary outcome was the difference in FOF between groups 7 days post inclusion, assessed by short Falls Efficacy Scale International (sFES-I). Secondary outcomes included feasibility, overall reduction of FOF, patient satisfaction, the occurrence of falls post inclusion and the use of medical resources.</p><p><strong>Results: </strong>Of the 1204 patients screened for inclusion, 104 older adults with a recent fall were enrolled (intervention: n = 44, control: n = 60); median age was 81 years and 59.1% were female. There was no between-group difference in FOF as measured by sFES-I within a week of inclusion (p = 0.663, effect size = 0.012 [95% confidence interval (CI) - 0.377 to 0.593]). Despite the intervention being deemed feasible from the physiotherapist's perspective, the study encountered challenges, such as low recruitment (with the planned sample size not being reached) and a notable dropout rate before the first follow-up.</p><p><strong>Conclusion: </strong>A physiotherapy intervention in the ED showed no improvement in FOF when compared to a control group.</p><p><strong>Trial registration: </strong>Trial registration number and date NCT05156944, 01.12.2021.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"205-217"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceptions of sarcopenia in patients, health and care professionals, and the public: a scoping review of studies from different countries.","authors":"Emma Grace Lewis, Christopher Hurst, Linda Errington, Avan A Sayer","doi":"10.1007/s41999-024-01132-5","DOIUrl":"10.1007/s41999-024-01132-5","url":null,"abstract":"<p><strong>Rationale and objective: </strong>Perceptions of sarcopenia have rarely been explored, yet understanding these will be key for successful translation of sarcopenia research findings into meaningful benefits for patients and the public. This scoping review aimed to explore how sarcopenia is perceived amongst patients, health and care professionals (HCP), and the public in different countries.</p><p><strong>Methods: </strong>Seven electronic databases were searched from inception up to December 2023 with no geographical or language limitations. Studies were included if they were peer-reviewed research of any design where the focus related to perceptions of sarcopenia. Studies using alternative descriptors only, such as \"skeletal muscle weakness/loss\" were excluded. Study characteristics were charted, and thematic synthesis conducted.</p><p><strong>Results: </strong>Following independent screening of 11,533 records, 20 articles were included in this review representing 19 countries. Five studies focused on patient perceptions, 11 investigated HCP, and four the public. Three key themes were identified: (1) Low awareness of sarcopenia-among all groups, its nature as a disease was contested. (2) The \"know-do\" gap in healthcare-even where knowledge among HCP existed, this had not translated into clinical practice, in part, due to perceptions of sarcopenia and its management. (3) Experiencing weakness-living with sarcopenia had physical and psychological sequalae.</p><p><strong>Key conclusions: </strong>These findings reveal perceptions that may be contributing to the slow adoption of sarcopenia prevention, screening, diagnosis, and management. Addressing these areas has the potential to aid translation of sarcopenia research findings into improved clinical care and benefits for patients and the public.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"99-113"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between serum sodium level ranges with geriatric syndromes.","authors":"Mehmet Ası Oktan, Cihan Heybeli, Ozcan Uzun, Lee Smith, Andre Hajek, Pinar Soysal","doi":"10.1007/s41999-024-01104-9","DOIUrl":"10.1007/s41999-024-01104-9","url":null,"abstract":"<p><strong>Purpose: </strong>To determine prevalences of common geriatric syndromes in the setting of different normal ranges of serum sodium.</p><p><strong>Methods: </strong>In this cross-sectional study, 2048 older adults (aged ≥ 60) who underwent comprehesive geriatric assessment between 2016 and 2023 in one geriatric outpatient clinic were evaluated. Patient groups included moderate hyponatremia (< 130 mEq/L, n = 28, 1.6%), mild hyponatremia (130-134 mEq/L, n = 130, 7.3%), lower-normal range (135-140 mEq/L, n = 904, 50.4%), upper normal range (141-145 mEq/L, n = 702, 39.2%), and hypernatremia (> 145 mEq/L, n = 29, 1.6%). A separate analysis was also performed according to the following classification: borderline hyponatremia (133-137 mEq/L), normal (138-142 mEq/L), and borderline hypernatremia (143-147 mEq/L). Logistic regression analysis was performed to determine associations between serum sodium groups and geriatric syndromes.</p><p><strong>Results: </strong>After applying the inclusion/ exclusion criteria a total of 1792 patients were included, with a mean age of 81 ± 8 years and 71% were female. With the exception of geriatric depression, all other syndromes were more prevalent in the lower-normal range than the upper normal range. After adjustments for age, sex, comorbidities, functional status, and drug exposures, upper normal range of serum sodium was associated with lower risks of dependency (OR 0.72, 95% CI 0.53-0.99, p = 0.043) and malnutrition (OR 0.69, 95% CI 0.51-0.94, p = 0.018). Compared to borderline hyponatremia, borderline hypernatremia was associated with lower risks of polypharmacy (OR 0.58, 95% CI 0.37-0.89, p = 0.014), dependency based on basic activities of daily living (OR 0.55, 95% CI 0.31-0.98, p = 0.042), malnutrition (OR 0.55 95% CI 0.33-0.91, p = 0.020), and frailty (OR 0.65, 95% CI 0.44-0.96, p = 0.031).</p><p><strong>Conclusions: </strong>Compared to a lower normal level of sodium, an upper normal level of sodium was associated with a lower risks of dependency and malnutrition. Borderline hypernatremia was associated with lower prevalences of polypharmacy, dependency, frailty, and malnutrition compared to borderline hyponatremia among geriatric outpatients in this single-center study.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"347-357"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}