European Geriatric Medicine最新文献

{"title":"Cross-sectional and longitudinal associations between glycaemic measures and grip strength in people without diabetes in the UK Biobank cohort study.","authors":"Antoneta Granic, Rachel Cooper, Christopher Hurst, Susan J Hillman, Richard M Dodds, Miles D Witham, Avan A Sayer","doi":"10.1007/s41999-024-01119-2","DOIUrl":"10.1007/s41999-024-01119-2","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate associations between glycaemic measures (HbA1c, random glucose), and grip strength (GS) in adults without prevalent diabetes.</p><p><strong>Methods: </strong>We included 381,715 UK Biobank participants aged 38-73 years without diabetes (any type) with complete baseline measures for GS and HbA1c (main analyses), and glucose (supplementary analyses). Cross-sectional sex- and age-stratified associations between each glycaemic measure, GS, and probable sarcopenia (low GS) were examined with regression analyses. Changes in GS over 8.9 years were classified into four groups (decline, stable low, stable high, or reference (increase or maintained within the normal range)) in 36,228 participants and associations with baseline glycaemic measures explored using multinomial regression.</p><p><strong>Results: </strong>Higher HbA1c (mmol/mol) was associated with weaker mean GS (kg) (regression coefficient and 95% confidence intervals (CI): - 0.08 (- 0.09, - 0.07)), and increased odds of probable sarcopenia (odds ratio (OR) and 95% CIs: 1.02 (95% CI: 1.01, 1.02)) in males and across the age groups. In females, higher HbA1c was associated with weaker mean GS only in mid-life (e.g., 50-59 years: - 0.06 (- 0.07, - 0.05)). In males, but not in females with repeated GS, higher HbA1c was associated with decreased odds of stable high (0.97 (0.96, 0.99) and increased odds of stable low (1.03 (1.01, 1.04)) GS pattern (0.98 (0.97, 0.980)) over the follow-up. The results for glucose in supplementary analyses were mixed, especially in females.</p><p><strong>Conclusions: </strong>The associations between HbA1c and GS in people without diabetes warrant replication and consideration of the effect on muscle strength when interventions to promote normoglycaemia are trialled.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"67-77"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Healthcare costs in relation to kidney function among older people: the SCOPE study.","authors":"Francesco Balducci, Mirko Di Rosa, Regina Roller-Wirnsberger, Gerhard Wirnsberger, Francesco Mattace-Raso, Lisanne Tap, Francesc Formiga, Rafael Moreno-González, Tomasz Kostka, Agnieszka Guligowska, Rada Artzi-Medvedik, Itshak Melzer, Christian Weingart, Cornel Sieber, Johan Ärnlöv, Axel C Carlsson, Fabrizia Lattanzio, Andrea Corsonello","doi":"10.1007/s41999-024-01086-8","DOIUrl":"10.1007/s41999-024-01086-8","url":null,"abstract":"<p><strong>Purpose: </strong>In this study, a comprehensive analysis of costs of chronic kidney disease (CKD) was performed, to understand factors associated with the economic burden of the disease in a multicentre international framework.</p><p><strong>Methods: </strong>The impact on costs of demographics, socio-economics, clinical, and functional variables was tested in 2204 subjects aged 75 years or more attending outpatient clinics in Europe using a multicentre 2-year prospective cohort study. By means of collected resources consumption and unit cost data a comprehensive cost database was built and then investigated using multilevel regression modeling.</p><p><strong>Results: </strong>Overall, hospitalization, medications and specialist visits were the main cost items, with a notable variability among countries. Estimated yearly costs were 4478€ ± 9804€, rising up to 6683€ ± 10,953€ for subjects with estimated Glomerular Filtration Rate (eGFR) < 30. Costs increased significantly according to the severity of the disease, gender and age. Clinical and functional covariates were also significantly associated with CKD-related total costs, even after correcting for the inter-country variability.</p><p><strong>Conclusion: </strong>Findings corroborate the importance of multidimensional assessment of participants with CKD, as multimorbidity and functional disability produce a detrimental impact on participant's prognosis and cost of care. Preservation of functional impairment and adequate management of comorbidities may thus help decreasing the overall consumption on health care resources in CKD patients, especially in older people.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"135-148"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between a lower T-CD4+ /CD8+ lymphocyte ratio and cognitive impairment in older persons with HIV.","authors":"Carlos Alberto Ruiz-Manríquez, José Alberto Avila-Funes, Fátima Brañas, Brenda Crabtree-Ramírez, Hélène Amieva, Virgilio Hernández-Ruiz","doi":"10.1007/s41999-024-01079-7","DOIUrl":"10.1007/s41999-024-01079-7","url":null,"abstract":"<p><strong>Purpose: </strong>To ascertain the association between the LT-CD4 + /CD8 + ratio and cognitive impairment in older people living with HIV.</p><p><strong>Methods: </strong>A cross-sectional study was conducted, including 207 adults aged > 50 years with HIV, receiving care at a tertiary-care hospital in Mexico City. Participants underwent a standardized geriatric and neuropsychological assessment to establish the presence of HIV-associated neurocognitive disorder according to the validated Antinori criteria. Multivariate logistic regression models were performed to determine the association between T-CD4 + /CD8 + lymphocyte ratio tercile values (0.57-0.91, and < 0.56; with > 0.91 being the reference category) and cognitive impairment.</p><p><strong>Results: </strong>Participants' median age was 56 (IQR 53-62) years and 173 (83.6%) were men. The prevalence of any kind of cognitive impairment according to the Antinori criteria was 66.2% (n = 137), the highest proportion being asymptomatic neurocognitive impairment (n = 114, 83.2%). Adjusted logistic regression analyses showed that the lowest LT-CD4 + /CD8 + ratio tercile values (< 0.56) were independently associated with the presence of cognitive impairment (OR 3.16; 95% CI 1.22-8.16, p = 0.017).</p><p><strong>Conclusion: </strong>Lower LT-CD4 + /CD8 + ratios are independently associated with cognitively impaired older persons with HIV, which represents another factor that could be addressed to identify individuals at risk and focus on cognitive screening as well as correction of other modifiable risk factors.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"305-313"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142548546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating irisin levels in patients with sarcopenia: a systematic review and meta-analysis.","authors":"Liangchuan Zhang, Yating Peng, Yuan Kong, Xue Zhang, Zetian Li, Hong Jia","doi":"10.1007/s41999-024-01097-5","DOIUrl":"10.1007/s41999-024-01097-5","url":null,"abstract":"<p><strong>Objective: </strong>During the aging process, a decrease in irisin levels is associated with numerous bone and muscle diseases. This study aims to provide evidence of circulating irisin levels in patients with sarcopenia.</p><p><strong>Methods: </strong>This systematic review was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standard and the recommendations of the Cochrane Collaboration. A comprehensive search was conducted in PubMed, Embase, Web of Science databases, and other sources from their establishment until August 2023. The Review Manager software version 5.4 was used to calculate the standard mean difference (SMD). I² statistics measured heterogeneity.</p><p><strong>Results: </strong>12 studies involving 2133 participants who met the inclusion criteria were analyzed. We found that irisin levels were significantly lower in patients with sarcopenia (SMD: - 1.28; 95% CI - 1.65, - 0.90; I² = 92% P < 0.001). Sensitivity analysis confirmed the robustness of this result. The correlation results showed that there was a positive correlation between the levels of circulating irisin and muscle mass (r value 0.62, 95% CI 0.31, 0.81; P < 0.001) and strength (r value 0.47, 95% CI 0.23, 0.66; P < 0.001), but no statistical correlation between irisin and muscle function (The P-values for gait speed and chair test time are 0.5523 and 0.1467, respectively).</p><p><strong>Conclusion: </strong>No matter the study area, study design, blood samples, or diagnostic criteria, the concentration of circulating irisin in patients with sarcopenia was lower than that in the control group.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"5-13"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142677636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on the predictive model of delirium risk after surgery for elderly hip fractures based on meta-analysis.","authors":"Weiliang Wan, Liyun Li, Zhuan Zou, Wenjie Chen","doi":"10.1007/s41999-024-01095-7","DOIUrl":"10.1007/s41999-024-01095-7","url":null,"abstract":"<p><strong>Objective: </strong>To develop and validate a risk prediction model for postoperative delirium in elderly patients with hip fractures, aiming to identify high-risk patients and implement preventive measures.</p><p><strong>Methods: </strong>A systematic search of five authoritative medical databases was conducted, retrieving a total of 1368 relevant articles. After screening, 44 high-quality studies were included in the meta-analysis, analyzing 13 potential risk factors, such as age, gender, diabetes, and history of stroke. A risk prediction model was constructed and validated in a cohort of 189 elderly hip fracture patients. The model's predictive performance was evaluated using ROC curves, with calibration assessed through the Hosmer-Lemeshow test, and clinical utility examined via Decision Curve Analysis (DCA) and Clinical Impact Curves (CIC).</p><p><strong>Results: </strong>The meta-analysis identified the following as independent risk factors for postoperative delirium: age (≥ 70 years), male gender, diabetes, history of stroke, preoperative comorbidities (≥ 2), previous delirium, preoperative cognitive impairment, low preoperative albumin levels (≤ 40 g/L), prolonged preoperative waiting time (≥ 48 h), anemia (≤ 100 g/L), ASA classification (≥ 3), use of general anesthesia, and prolonged surgery duration (≥ 2 h). The prediction model demonstrated strong efficiency in the validation cohort, with an AUC of 0.956, sensitivity of 87.3%, specificity of 94.8%, and a Brier score of 0.144, indicating high predictive accuracy and calibration. DCA and CIC analyses showed the model to have strong clinical decision-making value and impact across most thresholds.</p><p><strong>Conclusion: </strong>The risk prediction model developed in this study shows high predictive accuracy and clinical utility, making it valuable for identifying high-risk patients and implementing preventive measures in clinical practice. However, the study has limitations, such as potential retrospective bias, and further validation in larger, multicenter prospective studies is needed to confirm the model's broader applicability and stability.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"245-270"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of oral frailty with falls in long-term care residents.","authors":"Taija Puranen, Kaija Hiltunen, Kaisu H Pitkälä, Hanna-Maria Roitto, Päivi Mäntylä, Riitta K T Saarela","doi":"10.1007/s41999-024-01088-6","DOIUrl":"10.1007/s41999-024-01088-6","url":null,"abstract":"<p><strong>Purpose: </strong>We investigated the relationship between oral frailty (OFr) and falls among long-term care residents.</p><p><strong>Methods: </strong>Residents (N = 254, mean age 84 y, 79% women) participated in this longitudinal cohort study in 2018-2021. OFr was defined by six signs. Demographics, diagnoses, and medications were retrieved from the medical records. Frailty phenotype, sarcopenia and disability were assessed. Number of falls was collected from medical records over 12 months following baseline assessment.</p><p><strong>Results: </strong>Of participants, 35% fell during follow-up. Of the fallers, 28% were bedridden or needed a wheelchair; among non-fallers, this figure was 73%. In logistic regression analysis after adjusting for age, sex, BMI, stroke, dementia, diabetes, coronary heart disease, number of medications, mobility, walking speed and sarcopenia, OFr did not predict falls (OR for severe OFr 0.13 (95% CI 0.01-1.27). Male sex predicted falls.</p><p><strong>Conclusions: </strong>No association was found between severe OFr and falls over a 12-month follow-up.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"191-195"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11850447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, associated factors, and impact of vitamin B12 deficiency in older medical inpatients.","authors":"Ioanna Papakitsou, Andria Papazachariou, Theodosios Filippatos","doi":"10.1007/s41999-024-01093-9","DOIUrl":"10.1007/s41999-024-01093-9","url":null,"abstract":"<p><strong>Purpose: </strong>This retrospective cohort study aims to explore the prevalence of vitamin B12 deficiency in older hospitalized adults and identify key factors associated with this deficiency, as well as its impact on frailty and functional decline.</p><p><strong>Methods: </strong>Data were collected from older adults (≥65 years) sequentially admitted to the Internal Medicine Department of a tertiary university hospital. Clinical and laboratory characteristics, including age, sex, somatometric data, cause of admission, past medical history, chronic medication use, and laboratory tests, were recorded. Frailty and functional status were assessed using the Fried Frailty Scale (FFS), Clinical Frailty Scale (CFS), Barthel Index, and Katz Index. Vitamin B12 levels on admission were categorised as deficient (<200 pg/ml), borderline (200-300 pg/ml), normal (300-999 pg/ml), and high (≥1000 pg/ml).</p><p><strong>Results: </strong>A total of 894 patients were included. The median age was 83 years and 487 (54.5%) were females. The prevalence of vitamin B12 deficiency was found in 9.1%, while 17.3% of the sample had borderline levels. Multivariate analysis identified polypharmacy (≥5 drugs), low albumin levels/Geriatric Nutritional Risk Index (GNRI), and nursing home residency as independent factors associated with low B12 levels. Multivariate analyses showed that B12 deficiency was significantly associated with higher frailty rates and lower functional status.</p><p><strong>Conclusion: </strong>Vitamin B12 deficiency is prevalent among hospitalized older patients and is significantly associated with increased frailty and reduced functional status. These findings underscore the importance of routine screening for B12 deficiency in this vulnerable population to improve clinical outcomes and quality of life.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"337-346"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New onset seizures in Octogenarians.","authors":"Lakshmi Priya Lalitha, Ashalatha Radhakrishnan","doi":"10.1007/s41999-024-01105-8","DOIUrl":"10.1007/s41999-024-01105-8","url":null,"abstract":"<p><strong>Purpose: </strong>The occurrence of new seizure(s) in older adults is two- to three-fold higher as compared to the younger population, and previous studies have characterized the clinical features of seizures in patients beyond 60 or 65 years. This study, in response to the recent ILAE task force on epilepsy in the elderly (2023), has assessed the clinical characteristics of individuals who are over 85 years old.</p><p><strong>Methods: </strong>Data was collected from prospectively maintained electronic medical records, and the participants were divided into seizure-free and seizure-recurrence groups, and their clinical characteristics were compared.</p><p><strong>Results: </strong>Over a 30-year period, a single comprehensive epilepsy care center included a total of 40 patients, with a mean age of 88.7 ± 2.79 years - most common seizure type was generalized tonic-clonic seizures (45%), with a positive neuroimaging yield of 42.5% and an EEG showing specific abnormalities in 50% of cases. Etiology was unidentified in 50%, while stroke was the most common among identified etiologies (27.5%). Over a mean follow-up of 1.4 [0.2-5.8] years, monotherapy effectively controlled 62.5% of patients, but 47.5% experienced recurrence. When compared to the non-recurrence group, these patients showed significant risk factors such as a history of prior stroke [47.3% versus 23.8%, p = 0.031], use of phenytoin [68.4% versus 33.3%, p = 0.056], and clobazam [42.1% vs. 19%, p = 0.049].</p><p><strong>Conclusion: </strong>This study contributes to better identification and improved characterization of late-onset seizures and adds that appropriate, timely management results in better outcomes.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"373-378"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of pelvic floor muscles in community-dwelling women aged over 60: its relationship with urinary incontinence.","authors":"Yeşim Akkoç, Necmettin Yıldız, Bilge Yılmaz, Murat Ersöz, Ayşe Nur Bardak, Belgin Erhan, Kurtuluş Köklü, Hakan Tunç, Nurdan Paker, Aysun Özlü, Selcen Kanyilmaz, Engin Koyuncu, Ebru Alemdaroğlu, Hakan Alkan, Yasemin Yumuşakhuylu, Esra Cansu Selbes, Ezgi Yıldız, Nurdan Korkmaz, Zuhal Özişler, Gökhan Yardımcı, Meltem Güneş Akıncı, Saadet Nur Sena Öztekin, Tuğçe Aksungur, Ahmet Tarık Canbulat","doi":"10.1007/s41999-024-01083-x","DOIUrl":"10.1007/s41999-024-01083-x","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the awareness of the pelvic floor muscles (PFMs) and PFM exercises (PFME) knowledge, training and experience in community-dwelling women aged 60 and over and its relationship with urinary incontinence (UI).</p><p><strong>Methods: </strong>This is a questionnaire based study which was carried out in 9 Physical Medicine and Rehabilitation Centers, including a total of 500 women aged 60 and over and living in the community. The questionnaire included questions about awareness of PFMs, UI complaints and PFME knowledge, training and experience. Knowledge and awareness of PFMs and PFME knowledge, training and experience were compared in subgroups with or without urinary incontinence.</p><p><strong>Results: </strong>The mean age of the women included in the study was 67.8 ± 6.1 (60-88). Knowledge and awareness of PFMs and PFME knowledge, training and experience were low in the study population. Knowledge and awareness of PFMs were significantly low in the subgroup with urinary incontinence (p < 0.05). Kegel exercise training and experience were significantly low in the subgroup without urinary incontinence (p = 0.01, p < 0.01).</p><p><strong>Conclusion: </strong>Knowledge and awareness of PFMs and PFME knowledge, training and experience are low in community-dwelling women aged 60 and over and training programs should be organized to teach the function of the PFMs and to perform PFME correctly in this population.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"317-323"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep quality, daytime sleepiness, and risk of falling: results from an exploratory cross-sectional study.","authors":"Francesco Salis, Rosamaria Lecca, Maristella Belfiori, Michela Figorilli, Elisa Casaglia, Patrizia Congiu, Martina Mulas, Monica Maria Francesca Puligheddu, Antonella Mandas","doi":"10.1007/s41999-024-01092-w","DOIUrl":"10.1007/s41999-024-01092-w","url":null,"abstract":"<p><strong>Purpose: </strong>There is growing recognition of the importance of managing sleep disorders in the elderly, particularly given their complexity within a multidimensional framework. The aim of the present study is to investigate whether sleep quality and daytime sleepiness are associated with the risk of falls in older adults.</p><p><strong>Methods: </strong>This study included patients aged 75 years or older who were consecutively evaluated at the Geriatric Service, University Hospital of Monserrato, Cagliari, Italy. Participants underwent geriatric assessment, including sleep analysis using the Pittsburgh Sleep Quality Index (PSQI), and the Epworth Sleepiness Scale (ESS), as well as an assessment of risk of falls with Performance Oriented Mobility Assessment (POMA).</p><p><strong>Results: </strong>The study included 206 subjects, of whom 70.4% were women, with a median age of 83 years. A total of 141 participants (68.4%) had poor sleep quality, and 43 (20.9%) had excessive daytime sleepiness (EDS). Among people at high risk of falls, 85 participants had bad sleep quality, and 24 a satisfying one (χ²: 8.23, p = 0.0029); additionally, 77 participants did not exhibit daytime sleepiness, while 32 did (χ²: 9.03, p = 0.0027). To further explore these results, we designed logistic regressions, considering dichotomized PSQI and dichotomized ESS as independent variables, and dichotomized POMA as the dependent variable, and finally adjusted them for confounders. The adjusted model for PSQI yielded OR: 2.04 (95%CI 1.02-4.10), and the adjusted model for ESS yielded OR: 2.56 (95%CI 1.17-5.91).</p><p><strong>Conclusions: </strong>Our study demonstrated that an increased estimated risk of falling is associated with poor sleep quality and EDS in older adults, independently of the confounders.</p>","PeriodicalId":49287,"journal":{"name":"European Geriatric Medicine","volume":" ","pages":"197-204"},"PeriodicalIF":3.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}