International Braz J Urol最新文献

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Primary Retroperitoneal Lymph Node Dissection for Clinical Stage II A/B Seminomas: A Systematic Review and Meta-Analysis. 临床 II 期 A/B 半实体瘤的原发性腹膜后淋巴结清扫术:系统综述与元分析》。
IF 3.1 3区 医学
International Braz J Urol Pub Date : 2024-07-01 DOI: 10.1590/S1677-5538.IBJU.2024.0134
Bárbara Vieira Lima Aguiar Melão, Lucas Guimarães Campos Roriz de Amorim, Murilo Ribeiro Sanches, Giovanna Veiga Gomes, Douglas Mesadri Gewehr, Luis Henrique de Oliveira Moreira, Thaise Pedreira da Silva, Matheus de Melo Lobo, Gustavo Ruschi Bechara
{"title":"Primary Retroperitoneal Lymph Node Dissection for Clinical Stage II A/B Seminomas: A Systematic Review and Meta-Analysis.","authors":"Bárbara Vieira Lima Aguiar Melão, Lucas Guimarães Campos Roriz de Amorim, Murilo Ribeiro Sanches, Giovanna Veiga Gomes, Douglas Mesadri Gewehr, Luis Henrique de Oliveira Moreira, Thaise Pedreira da Silva, Matheus de Melo Lobo, Gustavo Ruschi Bechara","doi":"10.1590/S1677-5538.IBJU.2024.0134","DOIUrl":"10.1590/S1677-5538.IBJU.2024.0134","url":null,"abstract":"<p><strong>Introduction: </strong>Chemotherapy and radiation therapy are considered standard treatments for stage II seminoma patients; however, these therapies are associated with long-term toxicities. Recently, retroperitoneal lymph node dissection has emerged as an alternative strategy, and the first three phase II trials were published in 2023 with promising results. The present study conducted a systematic review and meta-analysis to evaluate this surgery as an alternative treatment for stage IIA/B seminoma patients.</p><p><strong>Purpose: </strong>Seminomas are the most common testicular tumors, often affecting young adult males. Standard treatments for stage II seminomas include chemotherapy and radiation therapy, but these therapies are associated with long-term toxicities. Thus, identifying alternative strategies is paramount. Herein, we conducted a systematic review and meta-analysis to appraise the efficacy and safety of retroperitoneal lymph node dissection (RPLND) for treating this condition.</p><p><strong>Methods: </strong>We systematically searched the PubMed, Embase, and Cochrane databases for studies evaluating RPLND as a primary treatment for stage II A/B seminomas. Using a random-effects model, single proportion and means and pooled 2-year recurrence-free survival rates with hazard rates and 95% CI were calculated.</p><p><strong>Results: </strong>Seven studies were included, comprising 331 males with stage II seminomas. In the pooled analysis, the recurrence rate was 17.69% (95% CI 12.31-24.75), and the 2-year RFS rate was 81% (95% CI 0.77-0.86). The complication rate was 9.16% (95% CI 6.16-13.42), the Clavien-Dindo > 2 complication rate was 8.83% (95% CI 5.76-13.31), and the retrograde ejaculation rate was 7.01% (95% CI 3.54-13.40). The median operative time was 174.68 min (95% CI 122.17-249.76 min), median blood loss was 105.91 mL (95% CI 46.89-239.22 mL), and patients with no evidence of lymph node involvement ranged from 0-16%.</p><p><strong>Conclusions: </strong>Primary RPLNDs for treating stage IIA/B seminomas have favorable RFS rates, with low complication and recurrence rates. These findings provide evidence that this surgery is a viable alternative therapy for these patients.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262717/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single-Port Transvesical Vesico-Vaginal Fistula Repair: An Initial Experience. 单孔经膀胱阴道瘘修补术:初步经验
IF 3.1 3区 医学
International Braz J Urol Pub Date : 2024-07-01 DOI: 10.1590/S1677-5538.IBJU.2024.0146
Donato Cannoletta, Antony Pellegrino, Greta Pettenuzzo, Matteo Pacini, Ruben Calvo Sauer, Juan R Torres-Anguiano, Luca Morgantini, Simone Crivellaro
{"title":"Single-Port Transvesical Vesico-Vaginal Fistula Repair: An Initial Experience.","authors":"Donato Cannoletta, Antony Pellegrino, Greta Pettenuzzo, Matteo Pacini, Ruben Calvo Sauer, Juan R Torres-Anguiano, Luca Morgantini, Simone Crivellaro","doi":"10.1590/S1677-5538.IBJU.2024.0146","DOIUrl":"10.1590/S1677-5538.IBJU.2024.0146","url":null,"abstract":"<p><strong>Introduction: </strong>Vesicovaginal fistula (VVF) is the most common urogenital fistula due to iatrogenic cause, primarily associated with gynecologic surgery (1). Although both conservative and surgical management may be considered, the optimal treatment is still uncertain and several studies were published using different techniques (open, laparoscopic or robotic) and approaches (extravesical, transvesical or transvaginal) (2-5). In this context, we aim to report our initial experience repairing VVF with Single-Port (SP) Transvesical (TV) access.</p><p><strong>Materials and methods: </strong>Four patients with a diagnosis of VVF underwent SP-TV VVF repair between May 2022 and December 2023. Diagnosis was confirmed by cystoscopy, cystogram and in two cases by CT Urogram. Under general anesthesia, before robotic time, patients were placed in lithotomy position and a preliminary cystoscopy was performed. Fistula was noted and a 5fr stent was placed through the fistulous tract. Two ureteral stents were placed. Then, with patient supine, a transverse suprapubic 3cm incision and 2cm cystotomy were made for SP access. First step was to mark and remove fistula tract to the vagina. The edges of the vagina and bladder were dissected in order to have a closure free of tension and to create three different layers to close: vagina, muscularis layer of the bladder and mucosal layer of the bladder. A bladder catheter was placed, and the two ureteral stents were removed at the end of procedure.</p><p><strong>Results: </strong>Mean age was 53 years old and three out of 4 patients developed VVF after gynecologic surgery. Two patients underwent VVF repair 6 and 8 months after total hysterectomy. One patient developed VVF after total hysterectomy and oophorectomy followed by radiation therapy. Last patient developed VVF after previous urological procedure. Fistula diameter was between 11 and 15mm. Operative time was 211 min, including preliminary cystoscopy, stents placement and SP-access. All patients were discharged on the same day with a bladder catheter, successfully removed between post-operative day 14-18 after negative cystogram. Only in one case a ureteral stent was left because the fistula was closed to the ureteral orifice and we reported one case of UTI twelve days after surgery, treated with outpatient antibiotics. Mean follow-up was 8 months, patients were scheduled for regular follow-up visits and no recurrence was reported. All patients have at least 3 months of post-operative follow-up.</p><p><strong>Conclusions: </strong>Our experience suggests that SP Transvesical VVF repair may be considered as a safe and feasible minimally invasive treatment for small/medium fistulae (10-15mm).</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Moment of induction and duration of experimental varicocele in rats: effects on semen quality. 大鼠实验性精索静脉曲张的诱导时刻和持续时间:对精液质量的影响。
IF 3.1 3区 医学
International Braz J Urol Pub Date : 2024-07-01 DOI: 10.1590/S1677-5538.IBJU.2023.0412
Renata Cristina de Carvalho, Rhayza Roberta Andretta, Jheysson Alfredo Cordeiro de Moura, Ricardo Pimenta Bertolla, Fatima Kazue Okada
{"title":"Moment of induction and duration of experimental varicocele in rats: effects on semen quality.","authors":"Renata Cristina de Carvalho, Rhayza Roberta Andretta, Jheysson Alfredo Cordeiro de Moura, Ricardo Pimenta Bertolla, Fatima Kazue Okada","doi":"10.1590/S1677-5538.IBJU.2023.0412","DOIUrl":"10.1590/S1677-5538.IBJU.2023.0412","url":null,"abstract":"<p><strong>Purpose: </strong>Varicocele is a condition known to cause damage to seminal parameters and sperm function. Furthermore, it has been hypothesized that the varicocele effect on fertility is time-dependent; however, little is known about the consequences of its establishment time on reproductive organs and/or sperm function. This study aimed to evaluate the effect of the duration of experimental varicocele on reproductive organs, sperm parameters, and sperm function.</p><p><strong>Materials and methods: </strong>Varicocele induction surgeries were performed in Wistar rats aged 40 or 100 days old. At 160-day-old, analyses were performed, including biometry of reproductive organs (prostate, seminal vesicles, epididymis, and testis), sperm parameters (vitality, morphology, and motility), and sperm function tests (nuclear DNA integrity, acrosome integrity, and mitochondrial activity).</p><p><strong>Results: </strong>The analysis of the biometry of reproductive organs showed no differences between distinct ages in which varicocele was induced. The total abnormal sperm morphology was bigger in animals with varicocele induced to 100 days old than in animals with varicocele induced to 40 days old. Regarding nuclear DNA integrity, animals of varicocele induced to 100 days old showed worse results compared to animals of varicocele induced to 40 days old. Other parameters analyzed showed no differences between varicocele groups.</p><p><strong>Conclusion: </strong>In this study conducted on rats, we conclude that varicocele adversely affects sperm, particularly its function. However, we did not observe a negative progressive effect on sperm.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental Model Exposed to Bisphenol and Submitted to a High-Fat Diet and Related Morphologic Testicular Parameters Alterations Analysis. 暴露于双酚并接受高脂饮食的实验模型及相关睾丸形态学参数变化分析。
IF 3.1 3区 医学
International Braz J Urol Pub Date : 2024-07-01 DOI: 10.1590/S1677-5538.IBJU.2024.9911
Jorge Luiz Alves Pereira, Luiz Carlos Schrotke Pires, Eliete Dalla Corte Frantz, Dangelo Carlo Magliano, Luciano Alves Favorito
{"title":"Experimental Model Exposed to Bisphenol and Submitted to a High-Fat Diet and Related Morphologic Testicular Parameters Alterations Analysis.","authors":"Jorge Luiz Alves Pereira, Luiz Carlos Schrotke Pires, Eliete Dalla Corte Frantz, Dangelo Carlo Magliano, Luciano Alves Favorito","doi":"10.1590/S1677-5538.IBJU.2024.9911","DOIUrl":"10.1590/S1677-5538.IBJU.2024.9911","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the morphological and stereological parameters of the testicles in mice exposed to bisphenol S and/or high-fat diet-induced obesity.</p><p><strong>Material and methods: </strong>Forty adult male C57BL/6 mice were fed a standard diet (SC) or high-fat diet (HF) for a total of 12 weeks. The sample was randomly divided into 4 experimental groups with 10 mices as follows: a) SC - animals fed a standard diet; b) SC-B - animals fed a standard diet and administration of BPS (25 μg/kg of body mass/day) in drinking water; c) HF: animals fed a high-fat diet; d) HF-B - animals fed a high-fat diet and administration of BPS (25 μg/Kg of body mass/day) in drinking water. BPS administration lasted 12 weeks, following exposure to the SC and HF diets. BPS was diluted in absolute ethanol (0.1%) and added to drinking water (concentration of 25 μg/kg body weight/day). The animals were euthanized, and the testes were processed and stained with hematoxylin and eosin (H&E) for morphometric and stereological parameters, including density of seminiferous tubules per area, length density and total length of seminiferous tubules, height of the tunica albuginea and the diameter of the seminiferous tubules. The images were captured with an Olympus BX51 microscope and Olympus DP70 camera. The stereological analysis was done with the Image Pro and Image J programs. Means were statistically compared using ANOVA and the Holm-Sidak post-test (p<0.05).</p><p><strong>Results: </strong>The seminiferous tubule density per area reduced in all groups when compared with SC samples (p<0.001): HF (40%), SC-B 3(2%), and HF-B (36%). Length density was reduced significantly (p<0.001) in all groups when compared with SC group: HF (40%), SC-B (32%), and HF-B (36%). The seminiferous tubule total length was reduced (p<0.001) when compared to f HF (28%) and SC-B (26%) groups. The tubule diameter increased significantly (p<0.001) only when we compared the SC group with SC (54%) an SC-B (25%) groups and the tunica thickness increased significantly only in HF group (117%) when compared with SC-B (20%) and HF-B 31%.</p><p><strong>Conclusion: </strong>Animals exposed to bisphenol S and/or high-fat diet-induced obesity presented important structural alterations in testicular morphology.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140923594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
International Brazilian Journal of Urology highlights experimental studies in Infertility in this number. 巴西国际泌尿学杂志》在本期中重点介绍了不孕不育方面的实验研究。
IF 3.1 3区 医学
International Braz J Urol Pub Date : 2024-07-01 DOI: 10.1590/S1677-5538.IBJU.2024.04.01
Luciano A Favorito
{"title":"International Brazilian Journal of Urology highlights experimental studies in Infertility in this number.","authors":"Luciano A Favorito","doi":"10.1590/S1677-5538.IBJU.2024.04.01","DOIUrl":"10.1590/S1677-5538.IBJU.2024.04.01","url":null,"abstract":"","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comprehensive Review of the Current State of Robot-assisted Laparoscopic Salvage Prostatectomy. 机器人辅助腹腔镜前列腺切除术现状全面回顾
IF 3.1 3区 医学
International Braz J Urol Pub Date : 2024-07-01 DOI: 10.1590/S1677-5538.IBJU.2024.0126
Parth U Thakker, Maxwell Sandberg, Ashok K Hemal, Alejandro R Rodriguez
{"title":"A Comprehensive Review of the Current State of Robot-assisted Laparoscopic Salvage Prostatectomy.","authors":"Parth U Thakker, Maxwell Sandberg, Ashok K Hemal, Alejandro R Rodriguez","doi":"10.1590/S1677-5538.IBJU.2024.0126","DOIUrl":"10.1590/S1677-5538.IBJU.2024.0126","url":null,"abstract":"<p><strong>Background and objective: </strong>Salvage robot assisted radical prostatectomy (sRARP) is performed for patients with biochemical or biopsy proven, localized prostate cancer recurrences after radiation or ablative therapies. Traditionally, sRARP has been avoided by lower volume surgeons due to technical demand and high complication rates. Post-radiation sRARP outcomes studies exist but remain few in number. With increasing use of whole gland and focal ablative therapies, updates on sRARP in this setting are needed. The aim of this narrative review is to provide an overview of recently reviewed studies on the oncologic outcomes, functional outcomes, and complications after post-radiation and post-ablative sRARP. Tips and tricks are provided to guide surgeons who may perform sRARP.</p><p><strong>Materials and methods: </strong>We performed a non-systematic literature search of PubMed and MEDLINE for the most relevant articles pertaining to the outlined topics from 2010-2022 without limitation on study design. Only case reports, editorial comments, letters, and manuscripts in non-English languages were excluded. Key Content and Findings: Salvage robotic radical prostatectomy is performed in cases of biochemical recurrence after radiation or ablative therapies. Oncologic outcomes after sRARP are worse compared to primary surgery (pRARP) though improvements have been made with the robotic approach when compared to open salvage prostatectomy. Higher pre-sRARP PSA levels and more advanced pathologic stage portend worse oncologic outcomes. Patients meeting low-risk, EAU-biochemical recurrence criteria have improved oncologic outcomes compared to those with high-risk BCR. While complication rates in sRARP are higher compared to pRARP, Retzius sparing approaches may reduce complication rates, particularly rectal injuries. In comparison to the traditional open approach, sRARP is associated with a lower rate of bladder neck contracture. In terms of functional outcomes, potency rates after sRARP are poor and continence rates are low, though Retzius sparing approaches demonstrate acceptable recovery of urinary continence by 1 year, post-operatively.</p><p><strong>Conclusions: </strong>Advances in the robotic platform and improvement in robotic experience have resulted in acceptable complication rates after sRARP. However, oncologic and functional outcomes after sRARP in both the post-radiation and post-ablation settings are worse compared to pRARP. Thus, when engaging in shared decision making with patients regarding the initial management of localized prostate cancer, patients should be educated regarding oncologic and functional outcomes and complications in the case of biochemically recurrent prostate cancer that may require sRARP.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140853058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of erectile dysfunction by intracavernosal administration of mesenchymal stem cells in patients with diabetes mellitus. 通过海绵体内注射间充质干细胞治疗糖尿病患者的勃起功能障碍。
IF 3.1 3区 医学
International Braz J Urol Pub Date : 2024-07-01 DOI: 10.1590/S1677-5538.IBJU.2024.0100
Yerbol Iskakov, Rustam Omarbayev, Rinat Nugumanov, Timur Turgunbayev, Yerkebulan Yermaganbetov
{"title":"Treatment of erectile dysfunction by intracavernosal administration of mesenchymal stem cells in patients with diabetes mellitus.","authors":"Yerbol Iskakov, Rustam Omarbayev, Rinat Nugumanov, Timur Turgunbayev, Yerkebulan Yermaganbetov","doi":"10.1590/S1677-5538.IBJU.2024.0100","DOIUrl":"10.1590/S1677-5538.IBJU.2024.0100","url":null,"abstract":"<p><p>Erectile dysfunction is observed in about 50% of men. It has been found that diabetes mellitus increases its prevalence to 19-86.3%, necessitating attention to a therapeutic strategy. Among the available treatment methods, intracavernosal injections of mesenchymal stem cells have proven to be particularly effective.</p><p><strong>Objective: </strong>The purpose of study is to assess and analyse the effectiveness of their use in the treatment of erectile dysfunction in patients with diabetes mellitus.</p><p><strong>Materials and methods: </strong>The literature search was conducted using systematic methods and analysis in databases such as Web of Science, Scopus, PubMed, Elsevier, and Springer, with 41 sources included for further review.</p><p><strong>Results: </strong>The study highlights microangiopathic and neuropathic links as key factors in erectile dysfunction development in diabetic patients, stemming from endothelial dysfunction and conductivity disturbances. Mesenchymal stem cell therapy from bone marrow, adipose tissue, and umbilical cord mitigates pathogenic impact through regenerative and anti-apoptotic effects. Due to this, most studies indicate high efficacy of the treatment and rapid therapeutic action through intracavernosal administration. Some studies suggest an increase in the body's receptor sensitivity to other drugs, such as sildenafil.</p><p><strong>Conclusion: </strong>From the perspective of further research on this issue, standardising the preparation of stem cells and the treatment method using a large sample size is essential to introduce such a method as an extremely promising therapy for this delicate issue in men into practical medicine. The practical value of the study lies in the systematisation of information on different sources of mesenchymal stem cells for treating erectile dysfunction.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262727/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140853307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Comment: Proximal Urethrostomy Versus Urethroplasty for Complex Urethral Strictures 巴西国际泌尿学杂志》在本期中重点介绍了不孕不育方面的实验研究。
IF 3.1 3区 医学
International Braz J Urol Pub Date : 2024-07-01 DOI: 10.1590/S1677-5538.IBJU.2024.9912
Luciano A Favorito
{"title":"Editorial Comment: Proximal Urethrostomy Versus Urethroplasty for Complex Urethral Strictures","authors":"Luciano A Favorito","doi":"10.1590/S1677-5538.IBJU.2024.9912","DOIUrl":"10.1590/S1677-5538.IBJU.2024.9912","url":null,"abstract":"","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141089183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Comment: What Adults Teach Urologists About Hypospadias? 社论评论:成人如何向泌尿科医生传授尿道下裂知识?
IF 3.7 3区 医学
International Braz J Urol Pub Date : 2024-05-01 DOI: 10.1590/S1677-5538.IBJU.2024.9910
Luciano A Favorito
{"title":"Editorial Comment: What Adults Teach Urologists About Hypospadias?","authors":"Luciano A Favorito","doi":"10.1590/S1677-5538.IBJU.2024.9910","DOIUrl":"10.1590/S1677-5538.IBJU.2024.9910","url":null,"abstract":"","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lower Urinary Tract Symptoms in a prospective cohort of COVID-19 survivors. COVID-19幸存者前瞻性队列中的下尿路症状。
IF 3.7 3区 医学
International Braz J Urol Pub Date : 2024-05-01 DOI: 10.1590/S1677-5538.IBJU.2023.0546
Cristiano M Gomes, Marcelo Hisano, Julia D Souza, João Victor T Henriques, Jose de Bessa, Julyana Moromizato, Thulio Bosi, Rachel Mazoni, João Gismondi, Bruno Camargo, Zein M Sammour, Homero Bruschini, Linamara R Battistella, William C Nahas
{"title":"Lower Urinary Tract Symptoms in a prospective cohort of COVID-19 survivors.","authors":"Cristiano M Gomes, Marcelo Hisano, Julia D Souza, João Victor T Henriques, Jose de Bessa, Julyana Moromizato, Thulio Bosi, Rachel Mazoni, João Gismondi, Bruno Camargo, Zein M Sammour, Homero Bruschini, Linamara R Battistella, William C Nahas","doi":"10.1590/S1677-5538.IBJU.2023.0546","DOIUrl":"10.1590/S1677-5538.IBJU.2023.0546","url":null,"abstract":"<p><strong>Purpose: </strong>To analyze the prevalence of lower urinary tract symptoms (LUTS) in patients who survived moderate and severe forms of COVID-19 and the risk factors for LUTS six months after hospitalization.</p><p><strong>Materials and methods: </strong>In this prospective cohort study, patients were evaluated six months after hospitalization due to COVID-19. LUTS were assessed using the International Prostate Symptom Score. General health was assessed through the Hospital Anxiety and Depression Scale and the EQ5D-L5 scale, which evaluates mobility, ability to perform daily activities, pain and discomfort and completed a self-perception health evaluation.</p><p><strong>Results: </strong>Of 255 participants, 54.1% were men and the median age was 57.3 [44.3 - 66.6] years. Pre-existing comorbidities included diabetes (35.7%), hypertension (54.5%), obesity (30.2%) and physical inactivity (65.5%). One hundred and twenty-four patients (48.6%) had a hospital stay >15 days, 181 (71.0%) were admitted to an ICU and 124 (48.6%) needed mechanical ventilation. Median IPSS was 6 [3-11] and did not differ between genders. Moderate to severe LUTS affected 108 (42.4%) patients (40.6% men and 44.4% women; p=0.610). Nocturia (58.4%) and frequency (45.9%) were the most prevalent symptoms and urgency was the only symptom that affected men (29.0%) and women (44.4%) differently (p=0.013). LUTS impacted the quality of life of 60 (23.5%) patients with women more severely affected (p=0.004). Diabetes, hypertension, and self-perception of worse general health were associated with LUTS.</p><p><strong>Conclusions: </strong>LUTS are highly prevalent and bothersome six months after hospitalization due to COVID-19. Assessment of LUTS may help ensure appropriate diagnosis and treatment in these patients.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":null,"pages":null},"PeriodicalIF":3.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11152335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140159290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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