International Braz J Urol最新文献

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The Perioperative Revolution in Muscle-Invasive Bladder Cancer - Progress, Caution, and the Latin American Perspective. 肌肉侵袭性膀胱癌围手术期的革命——进展、谨慎和拉丁美洲的观点。
IF 4.3 3区 医学
International Braz J Urol Pub Date : 2026-07-01 DOI: 10.1590/S1677-5538.IBJU.2026.0158
Caio Vinícius Suartz, Paulo Roberto Salustiano de Carvalho, Ricardo de Albuquerque Freitas, Augusto Modesto de Souza, Daher Cezar Chade, Leopoldo Alves Ribeiro, José Henrique Dallacqua Santiago, Daniel de Freitas G Soares, Karin Marise Jaeger Anzolch, Roni Fernandes de Carvalho, Fernando Korkes
{"title":"The Perioperative Revolution in Muscle-Invasive Bladder Cancer - Progress, Caution, and the Latin American Perspective.","authors":"Caio Vinícius Suartz, Paulo Roberto Salustiano de Carvalho, Ricardo de Albuquerque Freitas, Augusto Modesto de Souza, Daher Cezar Chade, Leopoldo Alves Ribeiro, José Henrique Dallacqua Santiago, Daniel de Freitas G Soares, Karin Marise Jaeger Anzolch, Roni Fernandes de Carvalho, Fernando Korkes","doi":"10.1590/S1677-5538.IBJU.2026.0158","DOIUrl":"10.1590/S1677-5538.IBJU.2026.0158","url":null,"abstract":"","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"52 4","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400065/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147516032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repositioning the Digital Rectal Examination in the Era of Risk-Adapted Prostate Cancer Diagnostics: Right Tool to the Right Patient at the Right Time. 在适应风险的前列腺癌诊断时代重新定位直肠指诊:正确的工具在正确的时间给正确的病人。
IF 4.3 3区 医学
International Braz J Urol Pub Date : 2026-07-01 DOI: 10.1590/S1677-5538.IBJU.2026.9907
Leonardo O Reis
{"title":"Repositioning the Digital Rectal Examination in the Era of Risk-Adapted Prostate Cancer Diagnostics: Right Tool to the Right Patient at the Right Time.","authors":"Leonardo O Reis","doi":"10.1590/S1677-5538.IBJU.2026.9907","DOIUrl":"10.1590/S1677-5538.IBJU.2026.9907","url":null,"abstract":"","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"52 4","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147515989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single Port Robotic Extraperitoneal Distal Ureterectomy and Ureteral Reimplantation via Lower Anterior Approach. 单端口机器人经下前路输尿管远端切除术及输尿管再植术。
IF 4.3 3区 医学
International Braz J Urol Pub Date : 2026-07-01 DOI: 10.1590/S1677-5538.IBJU.2026.0151
Arianna Biasatti, Savio D Pandolfo, Rocco Damiano, Marco De Sio, Ciro Imbimbo, Riccardo Autorino
{"title":"Single Port Robotic Extraperitoneal Distal Ureterectomy and Ureteral Reimplantation via Lower Anterior Approach.","authors":"Arianna Biasatti, Savio D Pandolfo, Rocco Damiano, Marco De Sio, Ciro Imbimbo, Riccardo Autorino","doi":"10.1590/S1677-5538.IBJU.2026.0151","DOIUrl":"10.1590/S1677-5538.IBJU.2026.0151","url":null,"abstract":"<p><strong>Purpose: </strong>Single Port (SP) Robotic Extraperitoneal approach enhances maneuverability in the narrow extraperitoneal space while preserving peritoneal integrity (1, 2). First reports show reduced postoperative pain, fewer gastrointestinal complications and shorter hospital stay compared to multiport or open techniques (3-5). Recent experiences with robotic ureteral reconstruction have further supported the feasibility of advanced reconstructive procedures in selected patients (6-8) but literature on SP platform remains limited (9, 10), therefore we present this innovative technique.</p><p><strong>Materials and methods: </strong>We report the case of a 44-year-old female (BMI 29.1 kg/m²), with medical history of fibromyalgia, who presented with right-sided back pain and nausea. CT-urogram showed severe right hydroureteronephrosis with a distal ureteral stricture and diffuse ureteral thickening, without a clear obstructing lesion. Diagnostic ureteroscopy revealed luminal narrowing due to wall thickening, without papillary masses. Biopsies and urine cytology were negative for urothelial carcinoma. A double-J stent was placed, and SP robotic distal ureterectomy with ureteral reimplantation was scheduled.</p><p><strong>Results: </strong>Low Anterior Access (LAA) was obtained through a 4-cm incision at the McBurney point. The retroperitoneal space was bluntly developed to identify the psoas muscle as anatomical landmark; the ureter was dissected caudally and resected at the level of the stricture. The bladder was then reached for cystotomy and ureteral reimplantation. Operative time was 160 minutes. No complications occurred and the patient was discharged on postoperative day 1. Final pathology revealed endometriosis. The ureteral stent was removed after 4 weeks; at 3-month follow-up the patient was asymptomatic, renal function was normal, and CT scan showed no right hydroureteronephrosis.</p><p><strong>Conclusion: </strong>Robotic SP extraperitoneal approach appears safe, feasible, and promising for ureteral reconstruction, combining retroperitoneal access with SP system dexterity and potentially reducing postoperative morbidity and hospital stay.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"52 4","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400075/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147437131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial Comment: Analysis of the Current Surgical Anatomical Knowledge of Radical Prostatectomy: An Updated Review. 编辑评论:根治性前列腺切除术的当前外科解剖学知识分析:最新综述。
IF 4.3 3区 医学
International Braz J Urol Pub Date : 2026-07-01 DOI: 10.1590/S1677-5538.IBJU.2026.9909
Luciano A Favorito
{"title":"Editorial Comment: Analysis of the Current Surgical Anatomical Knowledge of Radical Prostatectomy: An Updated Review.","authors":"Luciano A Favorito","doi":"10.1590/S1677-5538.IBJU.2026.9909","DOIUrl":"10.1590/S1677-5538.IBJU.2026.9909","url":null,"abstract":"","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"52 4","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400066/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147934983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robot-Assisted Sigmoid Colon Conduit for Urinary Diversion: Avoiding Bowel Anasto-mosis in a Patient with Prior Loop Colostomy and Pelvic Radiation. 机器人辅助乙状结肠导管用于尿分流:避免先前结肠环形造口和盆腔放疗患者的肠吻合。
IF 4.3 3区 医学
International Braz J Urol Pub Date : 2026-07-01 DOI: 10.1590/S1677-5538.IBJU.2026.0133
Éder Silveira Brazão, Caroline Almeida Gonçalves, Rodrigo Coelho Carvalho, Victor Espinheira Santos, Paulo Roberto Stevanato, Stênio Cássio Zequi
{"title":"Robot-Assisted Sigmoid Colon Conduit for Urinary Diversion: Avoiding Bowel Anasto-mosis in a Patient with Prior Loop Colostomy and Pelvic Radiation.","authors":"Éder Silveira Brazão, Caroline Almeida Gonçalves, Rodrigo Coelho Carvalho, Victor Espinheira Santos, Paulo Roberto Stevanato, Stênio Cássio Zequi","doi":"10.1590/S1677-5538.IBJU.2026.0133","DOIUrl":"10.1590/S1677-5538.IBJU.2026.0133","url":null,"abstract":"<p><strong>Purpose: </strong>Late radiation-induced genitourinary and gastrointestinal complications after multimodal treatment for pelvic malignancies frequently require complex reconstructive surgery, often necessitating both urinary and fecal diversion (1). In this setting, a colonic segment may provide an effective option for urinary diversion while avoiding bowel anastomosis (2, 3). Minimally invasive robotic approaches have increasingly expanded the feasibility of these complex reconstructions and may reduce morbidity, particularly in frail or previously irradiated patients (4-7). We describe a single-stage robot-assisted sigmoid colon conduit urinary diversion in a patient with a pre-existing loop colostomy.</p><p><strong>Materials and methods: </strong>A 46-year-old woman with prior pelvic chemoradiation developed a rectovaginal fistula requiring loop colostomy, followed by bilateral distal ureteral strictures, radiation cystitis, recurrent pyelonephritis, and a large parastomal hernia. After failed conservative management and preoperative nephrostomy placement, a single-stage robot-assisted procedure was performed. The operation included adhesiolysis, parastomal hernia repair, conversion of the loop to a terminal colostomy, and construction of a sigmoid colon urinary conduit. Ureterointestinal anastomoses were completed intracorporeally under indocyanine green fluorescence guidance.</p><p><strong>Results: </strong>The procedure was completed robotically without intraoperative complications. Total operative time was 95 minutes, with an estimated blood loss of 100 mL. Oral intake resumed on postoperative day 1, and the patient was discharged on day 3. At 6-month follow-up, renal function was preserved, with no recurrent infections or evidence of ureteral obstruction.</p><p><strong>Conclusion: </strong>Robot-assisted sigmoid colon conduit is a safe and reproducible option for urinary diversion in selected patients requiring concomitant bowel diversion, avoiding bowel anastomosis and reducing reconstructive morbidity.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"52 4","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400072/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147934980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transvesical Clipless Robot-Assisted Radical Prostatectomy Using a Multiport Plat-form: Technical Feasibility and Early Outcomes. 使用多通道平台的经膀胱无夹机器人辅助根治性前列腺切除术:技术可行性和早期结果。
IF 4.3 3区 医学
International Braz J Urol Pub Date : 2026-07-01 DOI: 10.1590/S1677-5538.IBJU.2025.0762
Thiago Camelo Mourão, Plínio Ramos Pinto, Jayme Quirino Caon Nobre, Ivan Augusto Agudo Miranda, Eduardo Zanotta Rodrigues, Gustavo de Pádua Brazão, Stênio de Cássio Zequi
{"title":"Transvesical Clipless Robot-Assisted Radical Prostatectomy Using a Multiport Plat-form: Technical Feasibility and Early Outcomes.","authors":"Thiago Camelo Mourão, Plínio Ramos Pinto, Jayme Quirino Caon Nobre, Ivan Augusto Agudo Miranda, Eduardo Zanotta Rodrigues, Gustavo de Pádua Brazão, Stênio de Cássio Zequi","doi":"10.1590/S1677-5538.IBJU.2025.0762","DOIUrl":"10.1590/S1677-5538.IBJU.2025.0762","url":null,"abstract":"<p><strong>Introduction: </strong>Robot-assisted radical prostatectomy (RARP) continues to evolve with surgical approaches aimed at preserving continence-related anatomy and optimizing postoperative recovery (1). Transvesical RARP has gained increasing interest, particularly with the advent of single-port platforms (2, 3). Building on our prior experience with clipless techniques and functional outcome optimization (4), we evaluated a multiport transvesical approach.</p><p><strong>Objective: </strong>To describe, step-by-step, a clipless transvesical RARP technique and to report its feasibility and early functional and oncologic outcomes.</p><p><strong>Materials and methods: </strong>An intravesical, line-of-sight technique was employed, with abdominal trocars positioned similarly to conventional transperitoneal RARP. The surgical sequence included: posterior release; longitudinal cystotomy with suspension sutures; semicircumferential bladder neck incision; bilateral clipless lateral dissection (blunt and sharp); anterior and apical release with dorsal venous complex control; urethral transection; urethrovesical anastomosis using two 3-0 barbed sutures; and single-layer cystotomy closure. Three consecutive patients with localized prostate cancer and moderate prostate volumes were included.</p><p><strong>Results: </strong>All procedures were completed as planned. Perioperative morbidity was low; one Clavien-Dindo grade II complication was managed conservatively. Early continence was observed in all patients, including at the first postoperative evaluation (45 days). One patient (Case 3) presented with a focal apical positive surgical margin on final pathology; prostate-specific antigen levels were undetectable in all cases during early follow-up. The approach was technically feasible and familiar to surgeons experienced in anterior RARP. Larger prostate volume may limit intravesical working space and apical visualization.</p><p><strong>Conclusions: </strong>We describe a reproducible clipless transvesical RARP performed using a multiport platform, addressing a body of literature predominantly focused on single-port systems. The technique demonstrated encouraging early functional outcomes in carefully selected patients (5); however, larger prostate volumes and longer follow-up are required to further define its oncologic and functional durability. This video complements our previous publication on alternative RARP approaches supporting anterior-preserving strategies (6).</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"52 3","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400064/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Which is the best laser for ureteroscopy? A Comprehensive Review. 输尿管镜的最佳激光是哪一种?全面审查。
IF 4.3 3区 医学
International Braz J Urol Pub Date : 2026-07-01 DOI: 10.1590/S1677-5538.IBJU.2026.0195
Vinícius Ravena Lourenço, João Pedro Leal Puppin, Fábio Carvalho Vicentini, Alexandre Danilovic, Giovanni Scala Marchini, Fábio César Miranda Torricelli, Carlos Alfredo Battagello, Rodrigo Perrella, Anderson Pellanda, William Carlos Nahas, Eduardo Mazzucchi
{"title":"Which is the best laser for ureteroscopy? A Comprehensive Review.","authors":"Vinícius Ravena Lourenço, João Pedro Leal Puppin, Fábio Carvalho Vicentini, Alexandre Danilovic, Giovanni Scala Marchini, Fábio César Miranda Torricelli, Carlos Alfredo Battagello, Rodrigo Perrella, Anderson Pellanda, William Carlos Nahas, Eduardo Mazzucchi","doi":"10.1590/S1677-5538.IBJU.2026.0195","DOIUrl":"10.1590/S1677-5538.IBJU.2026.0195","url":null,"abstract":"<p><strong>Purpose: </strong>The landscape of ureteroscopy has been transformed by rapid advancements in laser technology. The transition from the standard Holmium:YAG (Ho:YAG) to Thulium Fiber Laser (TFL) and emerging hybrid technologies (Magneto/Tm:YAG) creates decisional uncertainty. This review analyzes the physical principles, safety, and clinical outcomes of available lasers, proposing a context-based decision-making framework.</p><p><strong>Materials and methods: </strong>A literature review using PubMed and Embase (2014-2025) yielded 1,902 records. Search terms included \"holmium laser nephrolithotripsy,\" \"thulium fiber laser,\" and \"ureteroscopy laser.\" Fourteen seminal high-quality studies were selected for expert narrative synthesis, focusing on ablation efficiency, stone-free rates (SFR), complications, and cost-effectiveness.</p><p><strong>Results: </strong>Literature heterogeneity, particularly inconsistent SFR definitions and imaging modalities, challenges comparative analysis. Clinically, TFL demonstrates superior ablation speeds and dusting capabilities compared to standard Ho:YAG, with equivalent safety. However, High-Power Ho:YAG remains unmatched in versatility for complex stones. Emerging pulsed Tm:YAG and Magneto Cyber Ho systems theoretically combine peak power with dusting efficiency but require further validation. Economically, TFL and High-Power systems demand significantly higher capital investment than Low-Power alternatives.</p><p><strong>Conclusions: </strong>No universally superior laser exists; selection must be guided by institutional context. We propose a four-scenario framework: (1) Low-Power Ho:YAG is ideal for cost-sensitive, low-volume centers; (2) High-Power Ho:YAG is the standard for high-volume centers treating complex cases; (3) TFL is the choice for maximizing operative efficiency and dusting; and (4) Emerging Hybrid Technologies suit academic centers driving innovation. Future studies must prioritize standardized reporting to solidify the evidence base.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"52 4","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400078/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147935025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient-reported Outcomes of Transperineal Reanastomosis for Recurrent or Obliterative Post-prostatectomy Vesicourethral Anastomotic Stenosis. 经会阴吻合术治疗复发性或闭塞性前列腺切除术后膀胱尿道吻合术狭窄的患者报告结果。
IF 4.3 3区 医学
International Braz J Urol Pub Date : 2026-07-01 DOI: 10.1590/S1677-5538.IBJU.2026.0112
Jakob Klemm, Katharina Oberneder, Navid Roessler, Robert J Schulz, Max C Wagner, Victor M Schuettfort, Tim A Ludwig, Margit Fisch, Roland Dahlem, Malte W Vetterlein
{"title":"Patient-reported Outcomes of Transperineal Reanastomosis for Recurrent or Obliterative Post-prostatectomy Vesicourethral Anastomotic Stenosis.","authors":"Jakob Klemm, Katharina Oberneder, Navid Roessler, Robert J Schulz, Max C Wagner, Victor M Schuettfort, Tim A Ludwig, Margit Fisch, Roland Dahlem, Malte W Vetterlein","doi":"10.1590/S1677-5538.IBJU.2026.0112","DOIUrl":"10.1590/S1677-5538.IBJU.2026.0112","url":null,"abstract":"<p><strong>Purpose: </strong>Post-prostatectomy vesicourethral anastomotic stenosis (VUAS) affects up to 5% of patients. A subset of cases remains refractory to endoscopic treatment, significantly impacting quality of life in the long-term. This study presents 15-year follow-up data on patients undergoing open reanastomosis for refractory or obliterative VUAS.</p><p><strong>Patients and methods: </strong>We included patients who underwent transperineal vesicourethral reanastomosis from 2009-2023. The procedure was often staged, with artificial urinary sphincter (AUS) implantation three months later. Co-primary endpoints included retreatment-free survival (RFS) and patient-reported outcome measures (PROMs). RFS was analyzed with Kaplan-Meier estimators, and PROMs were evaluated per scoring manuals. Additionally, we conducted a scoping review of all studies reporting outcomes following complex VUAS reconstruction.</p><p><strong>Results: </strong>Among 46 patients with VUAS, prior endoscopic interventions included dilation (17%), incision (61%), and resection (80%). Median time from prostatectomy to reanastomosis was 23 months (IQR 16-42). At a median follow-up of 80 months (IQR 41-149), RFS rates were 91% at two years and 88% at five years. 30 patients (65%) required staged AUS implantation for stress urinary incontinence. PROMs, assessed in 28 patients (61%), indicated restored voiding function, absence of fecal incontinence, high treatment satisfaction, and low decision regret. Limitations include the absence of preoperative PROMs for baseline comparisons. The scoping review revealed varying success rates ranging from 60% to 92% and a significant underuse of validated PROMs.</p><p><strong>Conclusions: </strong>Transperineal reanastomosis offers an effective and lasting solution for treating recurrent or obliterative VUAS, with encouraging long-term results and favorable patient-reported outcomes, underscoring its critical role in salvage posterior urethral reconstruction after prostatectomy.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"52 4","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147935062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robot-Assisted Partial Nephrectomy is the Hot Topic in this Number of International Brazilian Journal of Urology. 机器人辅助部分肾切除术是本年度巴西国际泌尿外科杂志的热门话题。
IF 4.3 3区 医学
International Braz J Urol Pub Date : 2026-07-01 DOI: 10.1590/S1677-5538.IBJU.2026.04.01
Luciano A Favorito
{"title":"Robot-Assisted Partial Nephrectomy is the Hot Topic in this Number of International Brazilian Journal of Urology.","authors":"Luciano A Favorito","doi":"10.1590/S1677-5538.IBJU.2026.04.01","DOIUrl":"10.1590/S1677-5538.IBJU.2026.04.01","url":null,"abstract":"","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"52 4","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147934995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multicentre Validation of the 2019 Briganti Nomogram: One Threshold Does Not Fit All. 2019年布里甘蒂Nomogram多中心验证:一个阈值并不适合所有。
IF 4.3 3区 医学
International Braz J Urol Pub Date : 2026-07-01 DOI: 10.1590/S1677-5538.IBJU.2026.0023
Arthur Peyrottes, Fanny Orlhac, Alexandre Colau, Maxime Pattou, Yann Neuzillet, Fayek Taha, Stéphane Larré, François Desgrandchamps, Pierre Mongiat-Artus, Yves Allory, Alexandra Masson-Lecomte
{"title":"Multicentre Validation of the 2019 Briganti Nomogram: One Threshold Does Not Fit All.","authors":"Arthur Peyrottes, Fanny Orlhac, Alexandre Colau, Maxime Pattou, Yann Neuzillet, Fayek Taha, Stéphane Larré, François Desgrandchamps, Pierre Mongiat-Artus, Yves Allory, Alexandra Masson-Lecomte","doi":"10.1590/S1677-5538.IBJU.2026.0023","DOIUrl":"10.1590/S1677-5538.IBJU.2026.0023","url":null,"abstract":"<p><strong>Purpose: </strong>The 2019 Briganti nomogram is widely used to guide the indication for pelvic lymph node dissection (LND) at the time of radical prostatectomy in patients with localized prostate cancer. Although previously validated, its generalizability across distinct clinical settings remains uncertain.</p><p><strong>Materials and methods: </strong>We conducted a multicentre external validation of the nomogram in 481 patients from three French academic institutions (Centre A n=198, Centre B n=183 and Centre C n=100). Discrimination, calibration, and clinical utility were assessed. Spared LNDs and missed lymph node invasions (LNIs) were evaluated across risk thresholds.</p><p><strong>Results: </strong>The overall area under the receiver operating characteristics curve (AUC) was 0.733 but varied across centres (0.580-0.768). Calibration was acceptable overall but showed systematic overestimation in low-prevalence centres. At the 7% recommended threshold, the proportion of spared LNDs ranged from 51% to 76%, while missed LNIs ranged from 0% to 8.9%. Decision curve analysis revealed that the optimal threshold differed between centres.</p><p><strong>Conclusions: </strong>These results underscore the need for local validation and population-specific threshold adjustment before clinical implementation. Fixed thresholds may lead to under- or overtreatment depending on institutional case mix. Nomogram-based decision-making should be individualized based on local performance and patient-centred risk tolerance.</p>","PeriodicalId":49283,"journal":{"name":"International Braz J Urol","volume":"52 4","pages":""},"PeriodicalIF":4.3,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13400071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147934973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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