Brazilian Journal of Otorhinolaryngology最新文献

{"title":"Modified extracorporeal septoplasty: prospective study","authors":"Raphaella de Oliveira Migliavacca ,&nbsp;Michelle Lavinsky ,&nbsp;Olívia Egger de Souza ,&nbsp;Eduardo Priesnitz Friedrich ,&nbsp;Otávio Augusto Gonçalves Dias Cionek ,&nbsp;Leonardo Ferreira Subda ,&nbsp;Bárbara Luiza Bernardi","doi":"10.1016/j.bjorl.2024.101398","DOIUrl":"10.1016/j.bjorl.2024.101398","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to evaluate quality-of-life and satisfaction outcomes in patients undergoing the MES using the Portuguese version of the Nasal Obstruction Symptom Evaluation (NOSE-p) and Rhinoplasty Outcome Evaluation (ROE), and also to evaluate the frequency of possible complications of this technique.</p></div><div><h3>Methods</h3><p>We conducted a single-center prospective study with patients who had the indication for MES, from May 2016 to September 2020 at the Facial Plastic Surgery Clinic of Otolaryngology Department of the Hospital de Clinicas de Porto Alegre. The primary outcome was the relative postoperative change in NOSE-p. Secondary outcome was the variation in ROE, a validated quality-of-life questionnaire for rhinoplasty patients.</p></div><div><h3>Results</h3><p>Of the 31 patients submitted to extracorporeal septorhinoplasty who were evaluated, twenty-seven patients were included. Preoperative and postoperative NOSE-p scale scores were 65.2 ± 29.9 and 23.5 ± 26.7, respectively (mean differences of 42.04; [95% CI 27.35–56.73]; <em>p</em> &lt;  0.0001). Pre and postoperative ROE scores were 38.3 ± 24.3 vs. 67.29 ± 29.7, respectively (mean differences of −29.02; [95% CI −40.5 to −17.5]; <em>p</em> =  0.0001). Residual septal deviation was verified in 2 patients (7.4%).</p></div><div><h3>Conclusion</h3><p>Most of the patients submitted to modified extracorporeal septoplasty had a significant improvement in quality of life scores of nasal obstruction, with good aesthetical outcomes and low indices of postoperative complications.</p></div><div><h3>Level of evidence</h3><p>Level 3.</p></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1808869424000132/pdfft?md5=aefc7e31bfedda6b5288de2ef6f7cec6&pid=1-s2.0-S1808869424000132-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139956434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Squamous cell carcinoma arising from a cholesteatoma of the maxillary sinus: a case report⋆","authors":"Tae-Gyun Kim,&nbsp;Chang-Ho Whangbo,&nbsp;Jae-Ho Yoo,&nbsp;Hee-Jun Park,&nbsp;Sang-Yen Geum,&nbsp;Seung-Heon Shin,&nbsp;Mi Kyung Ye","doi":"10.1016/j.bjorl.2024.101408","DOIUrl":"10.1016/j.bjorl.2024.101408","url":null,"abstract":"","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1808869424000235/pdfft?md5=b79586854121f906e6f502df9785d313&pid=1-s2.0-S1808869424000235-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139949679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Position paper of diagnosis and treatment of post-extubation laryngitis in a multidisciplinary expert-based opinion","authors":"Débora Bressan Pazinatto ,&nbsp;Rebecca Maunsell ,&nbsp;Melissa Ameloti Gomes Avelino ,&nbsp;Jose Faibes Lubianca Neto ,&nbsp;Cláudia Schweiger ,&nbsp;Jamil Pedro de Siqueira Caldas ,&nbsp;Marcelo Barciela Brandão ,&nbsp;Paula Pires de Souza ,&nbsp;Fernanda Aparecida de Oliveira Peixoto ,&nbsp;Claudia Pires Ricachinevsky ,&nbsp;Rita C. Silveira ,&nbsp;Cinara Andreolio ,&nbsp;Carolina Sponchiado Miura ,&nbsp;Daniele da Silva Jordan Volpe ,&nbsp;Walusa Assad Gonçalves Ferri ,&nbsp;Fabiano Bleggi Gavazzoni ,&nbsp;Paulo Ramos David João ,&nbsp;Silmara Aparecida Possas ,&nbsp;Carlos Takahiro Chone","doi":"10.1016/j.bjorl.2024.101401","DOIUrl":"10.1016/j.bjorl.2024.101401","url":null,"abstract":"<div><h3>Objectives</h3><p>To make recommendations on the diagnosis and treatment of post-extubation laryngitis (PEL) in children with or without other comorbidities.</p></div><div><h3>Methods</h3><p>A three-iterative modified Delphi method was applied. Specialists were recruited representing pediatric otolaryngologists, pediatric and neonatal intensivists. Questions and statements approached topics encompassing definition, diagnosis, endoscopic airway evaluation, risk factors, comorbidities, management, and follow-up. A consensus was defined as a supermajority &gt;70%.</p></div><div><h3>Results</h3><p>Stridor was considered the most frequent symptom and airway endoscopy was recommended for definitive diagnosis. Gastroesophageal reflux and previous history of intubation were considered risk factors. Specific length of intubation did not achieve a consensus as a risk factor. Systemic corticosteroids should be part of the medical treatment and dexamethasone was the drug of choice. No consensus was achieved regarding dosage of corticosteroids, although endoscopic findings help defining dosage and length of treatment. Non-invasive ventilation, laryngeal rest, and use of comfort sedation scales were recommended. Indications for microlaryngoscopy and bronchoscopy under anesthesia were symptoms progression or failure to improve after the first 72-h of medical treatment post-extubation, after two failed extubations, and/or suspicion of severe lesions on flexible fiberoptic laryngoscopy.</p></div><div><h3>Conclusions</h3><p>Management of post-extubation laryngitis is challenging and can be facilitated by a multidisciplinary approach. Airway endoscopy is mandatory and impacts decision-making, although there is no consensus regarding dosage and length of treatment.</p></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1808869424000168/pdfft?md5=3c23be883b01b0590d22cdf9236f17ff&pid=1-s2.0-S1808869424000168-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139949609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A non-traditional endoscopic approach to laryngeal schwannoma","authors":"Petru Gurău","doi":"10.1016/j.bjorl.2024.101400","DOIUrl":"10.1016/j.bjorl.2024.101400","url":null,"abstract":"","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1808869424000156/pdfft?md5=f7302a1b2c197d92aaf37a5c226237e8&pid=1-s2.0-S1808869424000156-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139949680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New variants of ALMS1 gene and familial Alström syndrome case series","authors":"Isabela Carvalho de Queiroz,&nbsp;Natália Carasek,&nbsp;Luiza Costa Villela Ferreira,&nbsp;Lucas Alves Teixeira Oliveira,&nbsp;Fernando Massa Correia,&nbsp;Thaís Gomes Abrahão Elias,&nbsp;Fayez Bahmad Jr","doi":"10.1016/j.bjorl.2024.101402","DOIUrl":"10.1016/j.bjorl.2024.101402","url":null,"abstract":"<div><h3>Objectives</h3><p>To report two new variants of ALMS1 gene and to discuss the audiological evolution and clinical phenotype in two pairs of siblings with Alström syndrome.</p></div><div><h3>Report</h3><p>This paper is a multi-disciplinary diagnostic evaluation, with genetic and audiological analysis that aims to report two new variants of the ALMS1 gene and to discuss the audiological evolution and clinical phenotype in a case series of patients with familial Alström syndrome. Therefore, we describe 4 cases presenting a complete audiometric profile of two pairs of unrelated siblings, to provide a better understanding of this very rare disease. Additionally, the present study identified two heterozygous mutations in the ALMS1 gene.</p></div><div><h3>Conclusion</h3><p>This Clinical Capsule Report highlights the importance of audiological monitoring throughout the development of patients with Alström syndrome. The two variants found were not previously reported in the literature, which expands the spectrum of ALMS1 variants in Alström syndrome.</p></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S180886942400017X/pdfft?md5=4aa8cc8fb33f3d20138b38bf54bed606&pid=1-s2.0-S180886942400017X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139949989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of labetalol and lidocaine in induction of controlled hypotension in tympanoplasty: a randomized clinical trial","authors":"Ali Karami ,&nbsp;Zeinabsadat Fattahi Saravi ,&nbsp;Hossein Hosseini ,&nbsp;Mehdi Rahmati ,&nbsp;Reza Jahangiri ,&nbsp;Naeimehossadat Asmarian ,&nbsp;Mahsa Banifatemi","doi":"10.1016/j.bjorl.2024.101403","DOIUrl":"10.1016/j.bjorl.2024.101403","url":null,"abstract":"<div><h3>Objectives</h3><p>This study aimed to compare the efficacy of labetalol and lidocaine in tympanoplasty surgery, specifically evaluating their impact on hemodynamic changes and perioperative outcomes.</p></div><div><h3>Methods</h3><p>A randomized controlled trial was conducted with 64 patients scheduled for tympanoplasty. Patients were randomly assigned to receive either 0.5–2 mg/min labetalol or 1.5 mg/kg/h lidocaine 1% to achieve controlled hypotension during surgery. The efficacy of the drugs was assessed by comparing the Mean Arterial Pressure (MAP), surgeon's satisfaction, time to target MAP, bleeding volume, postoperative pain scores, the need for analgesic medication in recovery, sedation, and other additional parameters.</p></div><div><h3>Results</h3><p>The hemodynamic parameters showed a similar trend over time in both the labetalol and lidocaine groups. The median bleeding volume in the labetalol group (10 cc) was lower than that in the lidocaine group (30 cc), although this difference was not statistically significant (<em>p</em> = 0.11). Similarly, surgeon's satisfaction level, pain intensity, and sedation level in the recovery room did not show statistically significant differences between the two groups (<em>p</em> &gt; 0.05). The duration of surgery, recovery stay, and extubation time also did not significantly differ between the groups. Both medications took approximately the same time (20 min) to reach the target MAP and exhibited comparable hemodynamic responses (<em>p</em> &gt; 0.05).</p></div><div><h3>Conclusion</h3><p>Both labetalol and lidocaine effectively achieved controlled hypotension during tympanoplasty surgery, thereby improving surgical conditions. The choice of medication should be based on individual patient characteristics and the anesthesiologist's judgment.</p></div><div><h3>Level of evidence</h3><p>II.</p></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1808869424000181/pdfft?md5=75a62796ef886873db68629f515a8861&pid=1-s2.0-S1808869424000181-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139949983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Total laryngectomy vs. non-surgical organ preservation in advanced laryngeal cancer: a metanalysis","authors":"Elio Gilberto Pfuetzenreiter Jr. ,&nbsp;Gabriela Feltrini Ferreron ,&nbsp;Julia Zumerkorn Sadka ,&nbsp;Ana Beatriz Pádua de Souza ,&nbsp;Leandro Luongo Matos ,&nbsp;Luiz Paulo Kowalski ,&nbsp;Rogério Aparecido Dedivitis","doi":"10.1016/j.bjorl.2024.101404","DOIUrl":"10.1016/j.bjorl.2024.101404","url":null,"abstract":"<div><h3>Objective</h3><p>To compare the oncological results and the functional outcomes of patients undergoing Total Laryngectomy (TL) with the non-surgical treatment (organ preservation protocol) in the treatment of advanced laryngeal carcinomas through systematic review and meta-analysis.</p></div><div><h3>Methods</h3><p>A literature survey strategy was employed in order to perform a systematic review of the available evidence. Success rate and functional outomes after oncological treatment of patients with advanced laryngeal carcinomas was evaluated through systematic review and metanalysis, comparing TL and organ preservation protocol.</p></div><div><h3>Results</h3><p>The surgical treatment was associated with better survival outcomes. When stratifying by T stage, while patients with T4 staging have less risk of mortality with TL, there is no difference between the different treatments for patients with T3 tumors. Surgery is related to a lower chance of recurrence, late dysphagia and feeding tube dependence.</p></div><div><h3>Conclusion</h3><p>Patients with T4 tumors should undergo TL as their treatment of choice. For patients with T3 tumors, there is no differences on the risk of mortality according to the therapeutic option, however, there is a greater chance of recurrence and dysphagia when surgery is not performed.</p></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1808869424000193/pdfft?md5=24398b57bcd4df319043b6f40adfed87&pid=1-s2.0-S1808869424000193-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139949741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Giant laryngopharyngeal lipoma","authors":"Bo Li ,&nbsp;Xiaoming Fan ,&nbsp;Delong Liu ,&nbsp;Yang Song ,&nbsp;Cuiping She","doi":"10.1016/j.bjorl.2024.101407","DOIUrl":"10.1016/j.bjorl.2024.101407","url":null,"abstract":"","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1808869424000223/pdfft?md5=7dcb7d65592a98cebcdd8b7468ff53e7&pid=1-s2.0-S1808869424000223-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139956430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of treatment efficacy of omega-3 fish oil and montelukast in ovalbumin-protease-induced allergic rhinitis model in rats","authors":"Alper Tabaru ,&nbsp;Sahin Ogreden ,&nbsp;Salih Akyel ,&nbsp;Mehmet Faruk Oktay ,&nbsp;Kemal Uslu ,&nbsp;Funda Kaya Emre","doi":"10.1016/j.bjorl.2024.101399","DOIUrl":"10.1016/j.bjorl.2024.101399","url":null,"abstract":"<div><h3>Objectives</h3><p>Montelukast is a well-known leukotriene receptor antagonist commonly used in treating allergic rhinitis and asthma. Omega-3 fatty acid is also known as an antiallergic and immunomodulator molecule. This study aimed to elucidate the efficacy of systemic montelukast and omega-3 fatty acid treatment in allergic rhinitis models in Wistar Hannover rats.</p></div><div><h3>Methods</h3><p>This research was conducted on 28 healthy Wistar Hannover rats weighing 250–350 g. After establishing the allergic rhinitis model, nasal symptoms were observed and scored, and the nasal mucosa of all rats was investigated histologically. Light microscopy was utilized to evaluate the degree of ciliary loss, goblet cell hyperplasia, vascular congestion, vascular proliferation, inflammatory cell infiltration, eosinophil infiltration, and hypertrophy in chondrocytes.</p></div><div><h3>Results</h3><p>As a result of the analysis of the data obtained from the study, it was determined that typical allergic rhinitis symptoms such as nasal scratching and sneezing were significantly reduced in the rats in the montelukast and omega-3 treated group, and these symptoms did not increase after repeated intranasal OVA-protease applications. Histological examinations after fish oil treatment did not reveal typical inflammatory changes in allergic rhinitis. None of the rats in the montelukast and omega-3 groups had any increase in goblet cells, whereas 14.3% of the rats in the control group and 28.6% of the rats in the allergic rhinitis group had mild increase. Last but not least, 71.4% of rats in the allergic rhinitis group had a moderate increase. The difference between the groups was statistically significant (<em>p</em> &lt; 0.001).</p></div><div><h3>Conclusion</h3><p>Regarding the outcomes of this research, it was observed that w-3 fatty acids had antiallergic effects, both histopathological and clinical, in the allergic rhinitis model. We believe that further randomized controlled trials incorporating larger cohorts are warranted to verify the use of omega-3 fatty acids in treating allergic rhinitis.</p><p>The level of evidence of this article is Level 2.</p></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1808869424000144/pdfft?md5=34eecb07eea516194103344377b11c81&pid=1-s2.0-S1808869424000144-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139949604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Positional vertigo ‒ beyond benign paroxysmal positional vertigo: Case report","authors":"Lucas Scatolin Partezani,&nbsp;Raquel Mezzalira,&nbsp;Luis Augusto Guedes de Mello Dias,&nbsp;Daniela Akemi Souza Saito,&nbsp;Marina Saes Rays,&nbsp;Durval de Paula Chagas Neto","doi":"10.1016/j.bjorl.2024.101406","DOIUrl":"10.1016/j.bjorl.2024.101406","url":null,"abstract":"","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S1808869424000211/pdfft?md5=1dde935aa91d8f420c4d2afa03daff68&pid=1-s2.0-S1808869424000211-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139949677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}