Brazilian Journal of Otorhinolaryngology最新文献

{"title":"A novel cochlear implant assessment tool: Audiometric and speech recognition analysis","authors":"Fernanda Ferreira Caldas ,&nbsp;Byaka Cagnacci Buzo ,&nbsp;Bruno Sanches Masiero ,&nbsp;Alice Andrade Takeuti ,&nbsp;Carolina Costa Cardoso ,&nbsp;Fabiane de Castro Vaz ,&nbsp;Fayez Bahmad Jr.","doi":"10.1016/j.bjorl.2025.101559","DOIUrl":"10.1016/j.bjorl.2025.101559","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the results of Pure Tone Audiometry (PTA) and speech recognition, of users of Cochlear Implant (CI) between CLABOX with Direct Audio Input (DAI) and the Sound Booth (SB).</div></div><div><h3>Methods</h3><div>Fifty individuals with CIs, 33 adults and 17 children, were included. Speech recognition tests in noise fixed and adaptive were applied with the Hearing in Noise Test (HINT), Ling test, and PTA, in the SB (in free field) and in CLABOX.</div></div><div><h3>Results</h3><div>For speech recognition in noise, averages were better in the CLABOX; for PTA, they were higher in the CLABOX; and for Ling test, there was no significant change in the categories between SB and CLABOX. The fixed noise were higher in the CLABOX (88.3%) than in the SB (78.9%), <em>p</em>-value &lt; 0.001. In the HINT with adaptive noise, the results were significant (<em>p</em>-value = 0.007); the S/N ratio was 2.14 dB in the CLABOX and 3.42 dB in the SB. For the four-tone average, the average thresholds for the CLABOX and the SB were 29.8 dB and 23 dB, respectively (<em>p-</em>values &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>CLABOX was an effective tool to evaluate the PTA and speech recognition tests when compared to the conventional evaluation with a SB in the CI user population.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101559"},"PeriodicalIF":1.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143550260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensorineural hearing loss and CT abnormalities in otosclerosis: Insights from otopathological specimens","authors":"Rafael da Costa Monsanto ,&nbsp;Cassiano Mangini Dias Malpaga ,&nbsp;Hélio Kiitiro Yamashita ,&nbsp;Flávia Barros Suzuki ,&nbsp;Norma de Oliveira Penido","doi":"10.1016/j.bjorl.2025.101569","DOIUrl":"10.1016/j.bjorl.2025.101569","url":null,"abstract":"<div><h3>Objective</h3><div>To identify audiometric profiles of otosclerosis patients and present Computed Tomography (CT) findings with their otopathological correlates using human temporal bone specimens.</div></div><div><h3>Methods</h3><div>We analyzed sequential patients diagnosed with otosclerosis at a university hospital. Each patient underwent hearing evaluations and CT scans. We assessed the type and severity of hearing loss and the presence and location of otosclerotic foci. Audiometric results and CT images were compared. Additionally, representative otopathological specimens from the Paparella Otopathology &amp; Pathogenesis Laboratory were examined to understand the impact of otosclerotic foci on cochlear and inner ear structures.</div></div><div><h3>Results</h3><div>The study included 40 patients (25 female, 15 male; mean age 50.9 years, range 24–72). Most patients were white (62.5%), with others being black (35%) or Asian (2.5%). Symptoms typically began at age 36.4 years, with an average disease duration of 14.3 years. Audiometric analysis of 71 ears (excluding 9 previously operated) showed mixed hearing loss in 64.78%, sensorineural loss in 23.94%, conductive loss in 2.81%, and normal hearing in 8.45%. Our data revealed a significantly higher prevalence of sensorineural hearing loss among patients with otosclerosis compared to previous reports. This disparity may be due to our higher diagnostic rate, as CT scans were used for patients with unexplained sensorineural hearing loss, and the longer disease course related to delayed specialist access caused by structural issues in the Brazilian health system. Relevant CT findings are presented and compared with similar otopathology specimens.</div></div><div><h3>Conclusions</h3><div>Our study highlights a higher prevalence of mixed and sensorineural hearing loss in patients with otosclerosis than previously reported, suggesting that otosclerosis may be associated with more significant auditory impairment than commonly recognized. However, given the limitations of our retrospective design and the potential influence of co-morbidities, these findings should be interpreted with caution.</div></div><div><h3>Level of evidence</h3><div>2.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101569"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Docetaxel and cisplatin induction chemotherapy with or without fluorouracil in locoregionally advanced head and neck squamous cell carcinoma: A real-world data study","authors":"Matheus Yung Perin ,&nbsp;Vivian Naomi Horita ,&nbsp;Daniel Naves Araújo Teixeira ,&nbsp;Joyce Gruenwaldt ,&nbsp;Eduardo Baldon Pereira ,&nbsp;Carlos Takahiro Chone ,&nbsp;Gustavo Jacob Lourenço ,&nbsp;Ligia Traldi Macedo ,&nbsp;Carmen Silvia Passos Lima","doi":"10.1016/j.bjorl.2025.101572","DOIUrl":"10.1016/j.bjorl.2025.101572","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate outcomes of locoregionally advanced patients with Head and Neck Squamous Cell Carcinoma (HNSCC) treated with Induction Therapy (ICT).</div></div><div><h3>Methods</h3><div>Toxicity, response rate, and Event-Free Survival (EFS) and Overall Survival (OS) were evaluated in patients treated with docetaxel, cisplatin, and 5-Fluorouracil (TPF) or docetaxel and Cisplatin (TP).</div></div><div><h3>Results</h3><div>ICT regimens did not alter response to ICT, and patients’ EFS and OS. Cox multivariate analysis identified stable or progressive disease (HR = 5.56) and interval between cycles ≥28 days (HR = 2.79) as predictors of lower EFS, and ECOG ≥ 1 (HR = 3.42), stable or progressive disease (HR = 4.67), and interval between cycles ≥28 days (HR = 2.73) as predictors of lower OS.</div></div><div><h3>Conclusion</h3><div>Our findings indicate TP as a good treatment option for locoregionally advanced HNSCC, especially in socioeconomically limited settings.</div></div><div><h3>Level of evidence</h3><div>3.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101572"},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical study of the diagnosis of thyroid tumours using Raman spectroscopy","authors":"Qingjian He ,&nbsp;Lianjin Qin ,&nbsp;Yongqiang Yao ,&nbsp;WenJuan Wang","doi":"10.1016/j.bjorl.2025.101568","DOIUrl":"10.1016/j.bjorl.2025.101568","url":null,"abstract":"<div><h3>Objective</h3><div>The feasibility of the RS for the clinical diagnosis of thyroid tumours was explored.</div></div><div><h3>Methods</h3><div>The tumour specimens from 30 benign patients and 30 malignant patients were collected. The collected specimens were subjected to RS and histopathological analysis. The Raman peak intensities of all the specimens were calculated, and the data were analysed using discriminant analysis.</div></div><div><h3>Results</h3><div>(1) The prevalence rate of malignant tumours in females was as high as 76.7%. Central lymph node metastasis of malignant thyroid tumours accounted for 33.3% of cases, and lateral cervical lymph node metastasis accounted for only 6.7%. (2) The spectral intensity of malignant thyroid tumours was significantly greater than benign thyroid tumours at 1309 cm⁻¹, which should be the characteristic peak of thyroid cancer. The accuracy, sensitivity, and specificity of the RS for differentiating benign from malignant thyroid tumours were 95%, 83.3% and 89.2%.</div></div><div><h3>Conclusion</h3><div>RS is feasible for the diagnosis of thyroid tumours. This study provides experimental and clinical support for the wider application of RS in the evaluation of thyroid tissue.</div></div><div><h3>Levels of evidence</h3><div>: Levels 4.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101568"},"PeriodicalIF":1.7,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143512241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of TMEM71 as a hub NLRP3-related gene suppressing malignant behavior in nasopharyngeal carcinoma via the NLRP3/Caspase-1/GSDMD signaling pathway","authors":"Dan Liu,&nbsp;Yuanzhou Liu ,&nbsp;Ruixiang Cen","doi":"10.1016/j.bjorl.2025.101566","DOIUrl":"10.1016/j.bjorl.2025.101566","url":null,"abstract":"<div><h3>Objective</h3><div>NLRP3 plays a key role in cellular pyroptosis and tumor progression. However, research on NLRP3-Related Genes (NRGs) in Nasopharyngeal Carcinoma (NPC) is limited.</div></div><div><h3>Methods</h3><div>We analyzed the GSE53819 dataset to identify genes positively correlated with NLRP3 mRNA and downregulated in NPC tumors, termed NRGs. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were used to characterize their biological functions. Validation was performed using the GSE64634 and GSE102349 datasets. The GSE102349 dataset was used to evaluate the impact of NRGs on the Progression-Free Survival (PFS) and their association with immune cell infiltration. A cohort of 421 NPC patients from a local hospital underwent multivariate Cox regression to assess the prognostic significance of hub NRGs. Cellular experiments further investigated the role of hub NRGs in NPC.</div></div><div><h3>Results</h3><div>In the GSE53819 dataset, 26 NRGs were identified, correlated with NLRP3 expression, and downregulated in tumor tissues. GO and KEGG analyses linked these 26 NRGs to the inflammasome complex. TMEM71, identified in the GSE64634 and GSE102349 datasets, was downregulated in tumor tissues and positively correlated with NLRP3 expression. It was the only NRG with prognostic value, with higher expression correlating with improved PFS. Immune cell infiltration analysis showed significant differences between high and low TMEM71 expression groups (e.g., naïve B cells). Local analysis confirmed that positive TMEM71 expression in tumor serves as an independent prognostic marker for NPC (HR = 0.53, 95% CI 0.366‒0.780). in vitro, TMEM71 activation of the NLRP3/caspase-1/GSDMD pathway suppressed malignant behaviors in NPC cell.</div></div><div><h3>Conclusion</h3><div>TMEM71 may serve as a prognostic biomarker for NPC and influence immune cell infiltration. Its overexpression could exert anticancer effects via the NLRP3/caspase-1/GSDMD pathway, highlight its potential as a therapeutic target in NPC.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101566"},"PeriodicalIF":1.7,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143402977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Audiological findings in Brown Vialetto-Van-Laere Syndrome: A scoping review","authors":"Débora de Oliveira Rolim ,&nbsp;Leticia Cristina Vicente ,&nbsp;Hugo Amilton Santos de Carvalho ,&nbsp;Rebeca Lorrane Santana Santos ,&nbsp;Rivadávio Fernandes Batista de Amorim ,&nbsp;Fayez Bahmad Jr","doi":"10.1016/j.bjorl.2025.101558","DOIUrl":"10.1016/j.bjorl.2025.101558","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to characterize audiological porfile in inviduals with Brown-Vialetto-Van Laere syndrome (BVVLS).</div></div><div><h3>Methods</h3><div>This is a scoping review following the methodological structure developed by the Joana Briggs Institute (JBI). The PCC mnemonic was used to elaborate the research question, which resulted in the research question: “What are the audiological findings in individuals with BVVLS?”.</div></div><div><h3>Results</h3><div>All of the studies included in this review were case reports. The main audiological findings are sensorineural hearing loss and Auditory Neuropathy Spectrum Disorder (ANSD).</div></div><div><h3>Conclusion</h3><div>All individuals presented a severe to profound bilateral hearing loss, related to ANSD.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101558"},"PeriodicalIF":1.7,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143350069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Who’s afraid of Dura Mater?","authors":"Mario Emilio Zernotti ,&nbsp;Javier Gavilán","doi":"10.1016/j.bjorl.2024.101554","DOIUrl":"10.1016/j.bjorl.2024.101554","url":null,"abstract":"<div><h3>Objectives</h3><div>To overcome the fear associated with conventional nomenclature related to different anatomic positions for Bonebridge.</div></div><div><h3>Methods</h3><div>Bonebridge is an active transcutaneous semi-implantable bone conduction device available for clinical use since 2012. Bonebridge is indicated in patients with conductive and mild mixed hearing loss and a bone conduction threshold above 45 dB. This situation can be mainly found in patients with aural atresia, radical cavities, chronic otitis media and selected cases of otosclerosis not suitable for stapedectomy or hearing aids. The initial proposal was to position the implant in the mastoid, adjacent to the external ear canal. This position cannot be used in patients with radical cavities and should not be used in patients with aural atresia to avoid complications of future ear reconstructive surgery. New positions were soon implemented in the retrosigmoid and the middle fossa areas. However, the terms “retrosigmoid” and “middle fossa” are clearly linked to skull base surgery and create reluctancy among a large number of potential users.</div></div><div><h3>Results</h3><div>To avoid the negative reaction of otologic surgeons to these names we propose the use of easy to remember names related to the anatomic location of the implant. These names have been presented to the scientific community in meetings over the last decade and are now published in this short paper.</div></div><div><h3>Conclusion</h3><div>The new nomenclature proposed for the different anatomic positions available for Bonebridge is designed to stop the association between Bonebridge and skull base surgery.</div></div><div><h3>Level of evidence</h3><div>Level 2.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101554"},"PeriodicalIF":1.7,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143196934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochlear implantation in vestibular schwannoma: A game changer? A narrative review","authors":"Luis Lassaletta ,&nbsp;Miryam Calvino ,&nbsp;Isabel Sánchez-Cuadrado ,&nbsp;José Manuel Morales-Puebla ,&nbsp;Javier Gavilán","doi":"10.1016/j.bjorl.2025.101563","DOIUrl":"10.1016/j.bjorl.2025.101563","url":null,"abstract":"<div><h3>Objectives</h3><div>In recent years, indications for Cochlear Implants (CIs) have been on the rise, with Vestibular Schwannoma (VS) patients among these emerging indications. On the other hand, there is growing evidence in favor of the 'wait and see' approach as opposed to surgery or irradiation for most small VS. The aim of this paper is to discuss the current role of CIs in patients with VS, addressing the most controversial topics such as the variability of outcomes, the emerging clinical scenarios, the lack of consistent prognostic factors, and the need for an intraoperative tool to aid decision-making in challenging cases.</div></div><div><h3>Methods</h3><div>A Pubmed search was performed, with a selection of relevant citations, and critical appraisal of selected studies. Articles written in English on VS and cochlear implantation were eligible for inclusion. Pictures of illustrative cases from a tertiary center were included.</div></div><div><h3>Results</h3><div>The discussed topics were the following: (1) Variability in audiological outcomes; (2) Prognostic factors including tumor size, preoperative hearing, previous irradiation, extent of resection, and Neurofibromatosis type II <strong>(</strong>NF2) status; (3) Postoperative imaging; (4) The role of intraoperative testing; and (5) The current indication of CIs in different clinical scenarios.</div></div><div><h3>Conclusions</h3><div>CIs have become a useful solution for certain patients with VS. Audiological outcomes are variable, but worse than those of conventional CI candidates. Small and medium-sized tumors and those with a better preoperative hearing are more likely to benefit from a CI. The effect of irradiation is uncertain. Outcomes in NF2 patients may decrease in the long term. The auditory nerve test system is a useful intraoperative tool in most scenarios. The variability of the outcomes still precludes routine CI in VS with normal contralateral hearing. In addition to VS undergoing surgical resection and CI placement, some observed and irradiated VS cases also benefit from a CI.</div></div><div><h3>Level of evidence</h3><div>5.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101563"},"PeriodicalIF":1.7,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143196882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concentrated growth factors promote epithelization in the mastoid obliteration after canal wall down mastoidectomy","authors":"Mengyi Liu,&nbsp;Lue Zhang,&nbsp;Quanming Zhang,&nbsp;Nan Zeng,&nbsp;Shuo Li,&nbsp;Shuyue Guo,&nbsp;Yaqin Zhao,&nbsp;Mingxing Tang,&nbsp;Qiong Yang","doi":"10.1016/j.bjorl.2025.101561","DOIUrl":"10.1016/j.bjorl.2025.101561","url":null,"abstract":"<div><h3>Objective</h3><div>This retrospective study aimed at comparing the extent of epithelialization in mastoid obliteration after Canal Wall Down (CWD) mastoidectomy using Hydroxyapatite (HA) alone or using HA in combination with Concentrated Growth Factor (CGF) extracted from autologous blood.</div></div><div><h3>Methods</h3><div>A total of 56 patients undergoing the CWD mastoidectomy were enrolled. One group was treated by HA, while the other group received HA and CGF for mastoid obliteration (CGF/HA). A review of the medical follow-up records of all patients was conducted, with a primary focus on the otoendoscopic imaging materials. Complete epithelialization was determined by the absence of granulation, discharge, and swelling. The requisite period for complete epithelialization of the mastoid cavity was thus calculated, scored, and analyzed between treatments.</div></div><div><h3>Results</h3><div>Ear discharge, graft swelling, and poor blood supply were more frequently observed in the HA group. The proportion of patients group that achieved complete epithelialization within 60 days post operation was significantly higher in the CGF/HA group than the HA group. According to the scoring system for complete epithelialization, the median score of the CGF/HA group was 2, significantly higher than that of the HA treatment group (median score = 1, <em>p</em> = 0.032). Altogether, our results indicated that duration needed for complete epithelialization in the CGF/HA group was shorter than the control group.</div></div><div><h3>Conclusion</h3><div>The application of CGF to surgical cavity obliteration following a CWD mastoidectomy significantly promotes epithelialization, thereby achieving satisfactory results. Randomized controlled trials with a larger number of patients enrolled were worth launching in the future to better substantiate the value of CGF in obliteration of mastoid cavity.</div></div><div><h3>Level of evidence</h3><div>Level 2-Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101561"},"PeriodicalIF":1.7,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143196936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unilateral conductive hearing loss due to hydrocystoma in the external auditory canal: A rare case report","authors":"Francisco Campelo da Fonseca Neto,&nbsp;Renan Vieira de Brito,&nbsp;Eder Barbosa Muranaka,&nbsp;Arthur Menino Castilho","doi":"10.1016/j.bjorl.2025.101564","DOIUrl":"10.1016/j.bjorl.2025.101564","url":null,"abstract":"","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101564"},"PeriodicalIF":1.7,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143196883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}