Brazilian Journal of Otorhinolaryngology最新文献

{"title":"Isotretinoin use in rhinoplasty patients","authors":"Jholbert Cardoso Santana,&nbsp;Hugo Valter Ramos Lisboa,&nbsp;Leandro Azevedo de Camargo,&nbsp;Ricardo Araújo Meira Almeida,&nbsp;Lourival Mendes Bueno","doi":"10.1016/j.bjorl.2025.101592","DOIUrl":"10.1016/j.bjorl.2025.101592","url":null,"abstract":"<div><h3>Objective</h3><div>Presenting evidence available on perioperative isotretinoin application in, and benefits for, thick-skinned patients subjected to rhinoplasty.</div></div><div><h3>Methods</h3><div>Analysis was applied to articles available in the following databases: Cochrane, PubMed, ScienceDirect and Scielo. The analyzed corpus comprised studies published from 2004 to 2023 focused on investigating thick-skinned patients subjected to rhinoplasty and treated with isotretinoin. Inappropriate and unrelated methodologies were excluded from the analysis.</div></div><div><h3>Results</h3><div>Initially, 1,214 articles were collected, but this number dropped to 617 after duplicates’ removal. Twenty (20) articles remained in the corpus after inclusion criteria application, but 10 of them were excluded from the analysis based on exclusion criteria. Finally, 10 articles were selected for review purposes: 1 experience report, 2 case studies, 3 narrative reviews and 4 clinical trials.</div></div><div><h3>Conclusions</h3><div>The current findings suggested aesthetic improvements in patients treated with isotretinoin, although its long-term benefits remain uncertain. Thus, further research on this topic should be conducted.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 4","pages":"Article 101592"},"PeriodicalIF":1.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal study of hearing preservation and electrocochleography after cochlear implantation in adults","authors":"Marianne Schleich ,&nbsp;John J. Galvin III ,&nbsp;Fabrice Micaletti ,&nbsp;David Bakhos","doi":"10.1016/j.bjorl.2025.101584","DOIUrl":"10.1016/j.bjorl.2025.101584","url":null,"abstract":"<div><h3>Objectives</h3><div>Electrocochleography (ECOG) is a composite objective measure of the cochlea and the cochlear nerve responses. The objectives of this study were to investigate the evolution of ECOG after cochlear implantation and compare them with audiometric thresholds over a 12-month period.</div></div><div><h3>Methods</h3><div>A prospective monocentric study was conducted in Advanced Bionics cochlear implant recipients. Audiometric thresholds were recorded preoperatively and at 1-, 3-, 6-, and 12-months post cochlear implantation; ECOGs were recorded perioperatively after the electrode array insertion and at 1-, 3-, 6-, and 12-months post cochlear implantation. Cochlear Microphonic (CM) responses were measured by an apical electrode of the cochlear implant. Postoperative behavioral and ECOG thresholds were compared using Pearson correlation analyses.</div></div><div><h3>Results</h3><div>A total of 17 patients were included. At 1-year, residual hearing (≤90 dB HL at 500 Hz) was preserved for 4 out of 17 patients. Significant correlations were observed between perioperative ECOG and preoperative audiometric thresholds (<em>p</em> = 0.008), and between ECOG and audiometric thresholds at 3-months postoperative (<em>p</em> = 0.002).</div></div><div><h3>Conclusion</h3><div>ECOG can reflect changes in cochlear responses during and after implantation and may help to predict deterioration of residual hearing.</div></div><div><h3>Level of evidence</h3><div>Level 3.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 4","pages":"Article 101584"},"PeriodicalIF":1.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of the adjunctive use of photobiomodulation therapy in olfactory disorders in post-COVID-19 patients: A randomized controlled trial","authors":"Patricia Costa Oliveira ,&nbsp;Luisa Oliveira Correia ,&nbsp;Natalia Medeiros Dias Lopes ,&nbsp;Gabriel Rodrigues Suassuna ,&nbsp;Richard L. Doty ,&nbsp;Fabio de Rezende Pinna ,&nbsp;Richard Louis Voegels ,&nbsp;Marco Aurelio Fornazieri","doi":"10.1016/j.bjorl.2025.101583","DOIUrl":"10.1016/j.bjorl.2025.101583","url":null,"abstract":"<div><h3>Objectives</h3><div>Photobiomodulation Therapy (PBMT) is a non-invasive treatment that uses photons from the red to infrared spectrum to modulate cellular processes with anti-inflammatory and regenerative properties. This study aimed to evaluate the use of PBMT applied intranasally in patients with an impaired sense of smell after COVID-19. Methods: This proof-of-concept study was a randomized, placebo-controlled clinical trial that recruited 81 patients with olfactory disorders after SARS-CoV-2 infection (1–12 months), randomly assigned to 3 groups: controls, red light and infrared light exposure groups. PBMT was applied twice a week for five weeks, associated with prednisolone 40 mg for five days and olfactory training for 90 days from the first day of laser application. UPSIT® and subjective chemosensory scores were the outcomes collected before the first session and three months thereafter.</div></div><div><h3>Results</h3><div>Compared to controls, patients undergoing infrared PBMT showed more improvement in UPSIT® scores (+4.6 points, 95% CI: 1.5–7.8, <em>p</em> =  0.004) and a tendency towards reporting a better subjective smell score at the three-month follow-up. Response rates were 26.1% (95% CI: 6.7–45.5), 43.5% (95% CI: 21.6–65.4), and 68% (95% CI: 48.3–87.7) in the control, red and infrared groups, respectively. No major adverse events were reported.</div></div><div><h3>Conclusion</h3><div>Therapy with PBMT in the infrared frequency appears to be a safe option in treating post-COVID olfactory disorders when combined with a five-day use of systemic corticosteroid and 90 days of olfactory training.</div></div><div><h3>Level of evidence</h3><div>2.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 4","pages":"Article 101583"},"PeriodicalIF":1.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the frontal recess pneumatization pattern in patients with chronic frontal sinusopathy","authors":"Krystal Calmeto Negri ,&nbsp;Rogério Hamerschmidt ,&nbsp;Cassio Iwamoto ,&nbsp;Carolina Rodrigues Laranjeira Vilar","doi":"10.1016/j.bjorl.2025.101593","DOIUrl":"10.1016/j.bjorl.2025.101593","url":null,"abstract":"<div><h3>Objectives</h3><div>To analyze the pneumatization pattern of the frontal recess using CT scans and to determine the prevalence of frontoethmoidal cells and their possible correlation with the development of sinusopathy.</div></div><div><h3>Methods</h3><div>By means of a retrospective, analytical and cross-sectional study, 300 CT scans of patients with clinical suspicion of chronic rhinosinusitis were examined, separately on the right and left sides, totaling a sample of 600 paranasal sinuses, with regard to the presence of frontal cells, the presence of blockage or veiling of the recess and frontal sinus.</div></div><div><h3>Results</h3><div>Frontoethmoidal cells were present in 85.8% of cases; the most frequent cells were supra bulla cells, in 43.8%, and the least frequent were supraorbital ethmoid cells, in 11% of cases. There was a 35% prevalence of supra-Agger cells, 15.8% of supra-Agger frontal cells, 20.2% of supra bulla frontal cells and 12.3% of frontal septal cells. A significant relationship was found between the presence of supra-Agger frontal cells and supra bulla frontal cells and the development of sinusopathy.</div></div><div><h3>Conclusion</h3><div>The supra-Agger frontal cells and supra bulla frontal cells, when present in the frontal recess, predispose to the development of frontal sinusopathy. Therefore, preoperative tomographic analysis allows a three-dimensional anatomical understanding of the recess and frontal sinus based on determining the pneumatization pattern of this region.</div></div><div><h3>Level of evidence</h3><div>Level 3.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 4","pages":"Article 101593"},"PeriodicalIF":1.7,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital glossocervical fistula of presumed branchial origin: A unique anatomical pathway","authors":"Kento Koda ,&nbsp;Kenji Kondo ,&nbsp;Yuki Saito ,&nbsp;Tatsuya Yamasoba","doi":"10.1016/j.bjorl.2025.101567","DOIUrl":"10.1016/j.bjorl.2025.101567","url":null,"abstract":"","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101567"},"PeriodicalIF":1.7,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The pitfalls of positional dizziness: Not everything is crystal","authors":"Lucas Resende Lucinda Mangia ,&nbsp;Raquel Mezzalira ,&nbsp;Roseli Saraiva Moreira Bittar","doi":"10.1016/j.bjorl.2025.101575","DOIUrl":"10.1016/j.bjorl.2025.101575","url":null,"abstract":"","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101575"},"PeriodicalIF":1.7,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality-of-life assessment instruments for patients with vestibular schwannoma: A systematic review","authors":"Katarzyna Bieńkowska,&nbsp;Barbara Kostecka,&nbsp;Andrzej Kokoszka","doi":"10.1016/j.bjorl.2025.101585","DOIUrl":"10.1016/j.bjorl.2025.101585","url":null,"abstract":"<div><h3>Objective</h3><div>The European Association of Neuro-Oncology (EANO) indicated that different study designs and methodologies led to inconsistent conclusions about treatment methods and QoL in patients with Vestibular Schwannoma (VS). This study systematically reviews recent findings about QoL assessment instruments for patients with VS and provides recommendations for the measurement of QoL with standardized psychometric tools.</div></div><div><h3>Methods</h3><div>This study was conducted based on the PRISMA 2020 guideline for reporting systematic reviews. The key words used were as follows: quality of life, health-related quality of life, vestibular schwannomas, acoustic neuroma. Studies were included when the following eligibility criteria were met.</div></div><div><h3>Results</h3><div>Our search finally yielded 48 articles published in years 2014–2024 that measured QoL in patients with VS using standardized psychometric tools. The studies examined various dimensions of QoL. The most frequently used disease-specific questionnaire was the Penn Acoustic Neuroma Quality of Life (PANQOL). As a generic tool, authors preferred to use the Short-Form 36-Item Health Survey (SF-36).</div></div><div><h3>Conclusion</h3><div>Recent findings and data on Quality of Life (QoL) tools for patients with VS emphasize the importance of using standardized and disease specific tool like PANQOL, due to their frequent use and large amount of patient data. Although the SF-36 is commonly used for general assessments, it may not be sensitive enough for a complete QoL evaluation and should not be the only tool used. The GBI is effective for assessing changes after specific medical treatments. Using methods similar to those in past studies helps medical professionals make reliable conclusions about QoL and evaluate the effects of different treatments in VS patients.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101585"},"PeriodicalIF":1.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced age is not a predictor for cochlear implantation outcomes in adults with moderate to profound sensorineural hearing loss","authors":"Dayse Távora-Vieira ,&nbsp;Andre Wedekind ,&nbsp;Aanand Acharya ,&nbsp;Jafri Kuthubutheen ,&nbsp;Marcus Voola ,&nbsp;Vinicius Cavalheri ,&nbsp;Peter Friedland","doi":"10.1016/j.bjorl.2025.101571","DOIUrl":"10.1016/j.bjorl.2025.101571","url":null,"abstract":"<div><h3>Objective</h3><div>Hearing impairment is a common disability in elderly people. With an ageing population, it is expected that the number of people with age-related hearing loss will grow, and a proportion are likely to become Cochlear Implant (CI) candidates. The aim of this study is to investigate whether the age at which a person receives a CI has an impact on their objective speech understanding outcomes and subjective, self-reported outcomes within the first 12-months of CI use.</div></div><div><h3>Methods</h3><div>242 CI recipients participated in this study. Participants were divided into 3 groups according to age at implantation: 72 younger adults (18–60 years); 109 older adults (60–75 years); and 65 elderly adults (&gt;75-years). Benefit of CI use was assessed via speech understanding and patient-reported measures. Speech understanding in quiet was assessed via the Consonant-Nucleus-Consonant words test. Speech understanding in noise was assessed via the Bamford-Kowal-Bench Adaptive speech-in-noise test. Self-perceived hearing ability was assessed via the short from of the Speech, Spatial and Qualities of Hearing scale. Tinnitus reduction, if applicable, was assessed via the Tinnitus Reaction Questionnaire. All 4 assessments were completed at 4 intervals: preoperatively, 3-, 6-, and 12-months of CI use.</div></div><div><h3>Results</h3><div>For the entire cohort over time, significant improvements were found for speech understanding in quiet (<em>p</em> &lt; 0.0001), and self-perceived hearing ability (<em>p</em> &lt; 0.0001). Between the three groups, there were no significant differences in any postoperative (post-Op) assessment for all study outcomes.</div></div><div><h3>Conclusion</h3><div>Each age group had improved speech understanding and self-perceived hearing abilities after 12-months of CI use. No significant differences were found between groups at all post-Op test intervals. We therefore conclude that elderly people (&gt;75-years) who are acceptable CI candidates should be offered the same opportunity to benefit from CI use as younger adult candidates.</div></div><div><h3>Level of evidence</h3><div>Level 3.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101571"},"PeriodicalIF":1.7,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143679893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel cochlear implant assessment tool: Audiometric and speech recognition analysis","authors":"Fernanda Ferreira Caldas ,&nbsp;Byaka Cagnacci Buzo ,&nbsp;Bruno Sanches Masiero ,&nbsp;Alice Andrade Takeuti ,&nbsp;Carolina Costa Cardoso ,&nbsp;Fabiane de Castro Vaz ,&nbsp;Fayez Bahmad Jr.","doi":"10.1016/j.bjorl.2025.101559","DOIUrl":"10.1016/j.bjorl.2025.101559","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the results of Pure Tone Audiometry (PTA) and speech recognition, of users of Cochlear Implant (CI) between CLABOX with Direct Audio Input (DAI) and the Sound Booth (SB).</div></div><div><h3>Methods</h3><div>Fifty individuals with CIs, 33 adults and 17 children, were included. Speech recognition tests in noise fixed and adaptive were applied with the Hearing in Noise Test (HINT), Ling test, and PTA, in the SB (in free field) and in CLABOX.</div></div><div><h3>Results</h3><div>For speech recognition in noise, averages were better in the CLABOX; for PTA, they were higher in the CLABOX; and for Ling test, there was no significant change in the categories between SB and CLABOX. The fixed noise were higher in the CLABOX (88.3%) than in the SB (78.9%), <em>p</em>-value &lt; 0.001. In the HINT with adaptive noise, the results were significant (<em>p</em>-value = 0.007); the S/N ratio was 2.14 dB in the CLABOX and 3.42 dB in the SB. For the four-tone average, the average thresholds for the CLABOX and the SB were 29.8 dB and 23 dB, respectively (<em>p-</em>values &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>CLABOX was an effective tool to evaluate the PTA and speech recognition tests when compared to the conventional evaluation with a SB in the CI user population.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101559"},"PeriodicalIF":1.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143550260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensorineural hearing loss and CT abnormalities in otosclerosis: Insights from otopathological specimens","authors":"Rafael da Costa Monsanto ,&nbsp;Cassiano Mangini Dias Malpaga ,&nbsp;Hélio Kiitiro Yamashita ,&nbsp;Flávia Barros Suzuki ,&nbsp;Norma de Oliveira Penido","doi":"10.1016/j.bjorl.2025.101569","DOIUrl":"10.1016/j.bjorl.2025.101569","url":null,"abstract":"<div><h3>Objective</h3><div>To identify audiometric profiles of otosclerosis patients and present Computed Tomography (CT) findings with their otopathological correlates using human temporal bone specimens.</div></div><div><h3>Methods</h3><div>We analyzed sequential patients diagnosed with otosclerosis at a university hospital. Each patient underwent hearing evaluations and CT scans. We assessed the type and severity of hearing loss and the presence and location of otosclerotic foci. Audiometric results and CT images were compared. Additionally, representative otopathological specimens from the Paparella Otopathology &amp; Pathogenesis Laboratory were examined to understand the impact of otosclerotic foci on cochlear and inner ear structures.</div></div><div><h3>Results</h3><div>The study included 40 patients (25 female, 15 male; mean age 50.9 years, range 24–72). Most patients were white (62.5%), with others being black (35%) or Asian (2.5%). Symptoms typically began at age 36.4 years, with an average disease duration of 14.3 years. Audiometric analysis of 71 ears (excluding 9 previously operated) showed mixed hearing loss in 64.78%, sensorineural loss in 23.94%, conductive loss in 2.81%, and normal hearing in 8.45%. Our data revealed a significantly higher prevalence of sensorineural hearing loss among patients with otosclerosis compared to previous reports. This disparity may be due to our higher diagnostic rate, as CT scans were used for patients with unexplained sensorineural hearing loss, and the longer disease course related to delayed specialist access caused by structural issues in the Brazilian health system. Relevant CT findings are presented and compared with similar otopathology specimens.</div></div><div><h3>Conclusions</h3><div>Our study highlights a higher prevalence of mixed and sensorineural hearing loss in patients with otosclerosis than previously reported, suggesting that otosclerosis may be associated with more significant auditory impairment than commonly recognized. However, given the limitations of our retrospective design and the potential influence of co-morbidities, these findings should be interpreted with caution.</div></div><div><h3>Level of evidence</h3><div>2.</div></div>","PeriodicalId":49099,"journal":{"name":"Brazilian Journal of Otorhinolaryngology","volume":"91 3","pages":"Article 101569"},"PeriodicalIF":1.7,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}