Clinical outcomes of high-frequency electrocautery surgery and proton pump inhibitor therapy for refractory laryngeal contact granuloma

IF 1.8 4区医学 Q2 OTORHINOLARYNGOLOGY

Brazilian Journal of Otorhinolaryngology Pub Date : 2025-07-29 DOI:10.1016/j.bjorl.2025.101690

Zelong Wang, Xianbin Lan, Yuan Fang, Shaoping Peng, Riqun Jin, Dongming Deng, Zhiheng Song

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引用次数: 0

Abstract

Objective

To evaluate the clinical efficacy of high-frequency electrocautery under electronic laryngoscopy combined with acid-suppressing drugs (Proton Pump Inhibitor, PPI) in the treatment of Refractory Laryngeal Contact Granuloma (RLCG).

Methods

A total of 42 patients with RLCG, treated at our hospital from January 2019 to January 2024 were included in this study. The patients underwent high-frequency electrocautery to excise laryngeal granulomas under local anesthesia using electronic laryngoscopy, followed by PPI therapy. Follow-up started one-month post-surgery and lasted for 6–12 months (average of 8.5 months), to assess the cure rate and overall efficacy.

Results

The cure rate was 76.19%, and the overall efficacy rate was 92.86%. On average, each patient underwent 1.79 procedures. The combined treatment of high-frequency electrocautery under local anesthesia with electronic laryngoscopy and PPI therapy demonstrated significant therapeutic effects for RLCG. The treatment was simple, well-tolerated by patients, cost-effective, and resulted in rapid symptom improvement, all without the need for general anesthesia or intubation.

Conclusion

The combined approach of high-frequency electrocautery under local anesthesia with electronic laryngoscopy and PPI therapy is effective in treating refractory laryngeal contact granuloma. This method offers the advantages of a straightforward surgical procedures, high patient tolerance, low cost, quick symptom relief, and no requirement for general anesthesia or intubation.

Level of evidence

Level 4-Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence.

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高频电切联合质子泵抑制剂治疗难治性喉部接触性肉芽肿的临床效果

目的评价电子喉镜下高频电灼联合抑酸药物（质子泵抑制剂，PPI）治疗难治性喉接触性肉芽肿（RLCG）的临床疗效。方法选取2019年1月至2024年1月在我院治疗的42例RLCG患者作为研究对象。患者在局麻下采用电子喉镜下高频电切切除喉部肉芽肿，然后进行PPI治疗。术后1个月开始随访，随访6 ~ 12个月（平均8.5个月），评估治愈率和总疗效。结果治愈率为76.19%，总有效率为92.86%。平均每位患者接受1.79次手术。局麻高频电灼联合电子喉镜和PPI治疗RLCG疗效显著。该治疗方法简单，患者耐受性好，成本效益高，症状改善迅速，无需全身麻醉或插管。结论局麻高频电灼联合电子喉镜治疗难治性喉部接触性肉芽肿疗效显著。该方法具有手术操作简单、患者耐受性高、费用低、症状缓解快、不需要全身麻醉或插管等优点。证据水平4级牛津循证医学中心2011证据水平。

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来源期刊

Brazilian Journal of Otorhinolaryngology OTORHINOLARYNGOLOGY-

CiteScore

3.00

自引率

0.00%

发文量

205

审稿时长

4-8 weeks

期刊介绍： Brazilian Journal of Otorhinolaryngology publishes original contributions in otolaryngology and the associated areas (cranio-maxillo-facial surgery and phoniatrics). The aim of this journal is the national and international divulgation of the scientific production interesting to the otolaryngology, as well as the discussion, in editorials, of subjects of scientific, academic and professional relevance. The Brazilian Journal of Otorhinolaryngology is born from the Revista Brasileira de Otorrinolaringologia, of which it is the English version, created and indexed by MEDLINE in 2005. It is the official scientific publication of the Brazilian Association of Otolaryngology and Cervicofacial Surgery. Its abbreviated title is Braz J Otorhinolaryngol., which should be used in bibliographies, footnotes and bibliographical references and strips.