Journal of Oral & Facial Pain and Headache最新文献

{"title":"Comparative analysis of pain experience and quality of life in patients with oral lichen planus and burning mouth syndrome.","authors":"Ji-Won Kim, Hyo-Jung Jung, Je-Hyun Eom, Jong-Hoon Choi, Jeong-Seung Kwon, Mu-Yeol Cho, Yunwoo Kim, Young-Youn Kim, Hanseung Baek, Hye-Sung Kim, Hyung-Joon Ahn","doi":"10.22514/jofph.2026.060","DOIUrl":"https://doi.org/10.22514/jofph.2026.060","url":null,"abstract":"<p><strong>Background: </strong>Oral lichen planus (OLP) and burning mouth syndrome (BMS) are chronic oral conditions associated with persistent pain, but direct comparisons of their pain profiles and contributing factors remain limited. This study compared factors influencing pain perception between OLP and BMS.</p><p><strong>Methods: </strong>This cross-sectional study included 46 patients with OLP and 50 with BMS. Pain characteristics, pain catastrophizing, and quality of life were assessed using the Brief Pain Inventory-Korean version, Pain Catastrophizing Scale-Korean version, and a Korean-language Oral Potentially Malignant Disorders Quality of Life questionnaire. Normality was assessed using the Shapiro-Wilk test; Mann-Whitney U or independent <i>t</i>-tests were applied accordingly, and effect sizes were calculated using Cohen's <i>d</i>. Pain intensity predictors were identified using stepwise multiple linear regression.</p><p><strong>Results: </strong>Patients with BMS reported higher pain intensity (<i>p</i> ≤ 0.003, <i>d</i> = -1.22 to -0.63) and catastrophizing (<i>p</i> = 0.005, <i>d</i> = -0.56) than those with OLP, whereas patients with OLP showed greater mastication-related pain interference (<i>p</i> = 0.002, <i>d</i> = 0.74) and poorer quality of life (<i>p</i> = 0.020, <i>d</i> = 0.50). Regression identified mastication and rumination in OLP (adjusted <i>R</i>² = 0.419) and sleep disturbance, rumination, and magnification in BMS (adjusted <i>R</i>² = 0.454) as primary predictors. Age stratification revealed an opposite age-pain relationship: older patients with BMS (>60 years) had higher pain intensity (<i>p</i> < 0.001), whereas younger patients with OLP (≤60 years) reported higher pain intensity (<i>p</i> = 0.037). Pain interference was more interconnected across life domains in OLP (27 correlations with |<i>r</i>| > 0.5) than in BMS (6 correlations).</p><p><strong>Conclusions: </strong>OLP and BMS exhibit distinct pain profiles, with OLP characterized by widespread functional interference influenced by mastication-related and cognitive factors, and BMS marked by higher pain intensity with prominent psychological contributors. Condition-specific strategies incorporating cognitive behavioral therapy targeting rumination may improve pain-related outcomes.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"40 5","pages":"54-64"},"PeriodicalIF":2.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resting-state fMRI correlates of acupuncture in migraine: a coordinate-based meta-analysis.","authors":"Guo-Yun Liu, Ling-Hua Li, Zi-Min Cao, Zhe Chen, Zi-Chen Wang, Yi-Kun Yuan, Chao-Qun Yan, Jun Wang","doi":"10.22514/jofph.2026.058","DOIUrl":"10.22514/jofph.2026.058","url":null,"abstract":"<p><strong>Background: </strong>Although acupuncture has shown prophylactic benefits for migraine, its neural mechanisms remain elusive. This study systematically synthesized whole-brain resting-state functional magnetic resonance imaging (fMRI) evidence to characterize changes in spontaneous brain activity after acupuncture treatment in patients with migraine.</p><p><strong>Methods: </strong>We systematically searched eight databases for resting-state fMRI studies that used whole-brain analyses to compare patients with migraine before and after acupuncture. Only studies reporting amplitude of low-frequency fluctuation (ALFF) or regional homogeneity (ReHo) were eligible for quantitative meta-analysis. Seed-based d Mapping with Permutation of Subject Images (SDM-PSI) was used to conduct the coordinate-based meta-analysis. Meta-regression analyses explored associations between regional brain changes and clinical outcomes.</p><p><strong>Results: </strong>Thirteen studies comprising 19 datasets and 312 patients were included. At the prespecified uncorrected SDM-PSI threshold, acupuncture treatment was associated with increased ALFF in the right middle frontal gyrus and increased ReHo in the left angular gyrus and right superior temporal gyrus, together with decreased ReHo in the right precuneus. Exploratory meta-regression suggested that greater pain reduction was associated with smaller ReHo increases in the right superior temporal gyrus, whereas greater reduction in attack frequency was associated with greater ReHo increases in the left angular gyrus.</p><p><strong>Conclusions: </strong>Acupuncture may be associated with altered spontaneous neural activity in regions of the executive control network, default mode network, and multisensory processing regions. These findings provide preliminary neuroimaging evidence for the central correlates of acupuncture in migraine. However, they should be interpreted cautiously given the limited evidence base, methodological heterogeneity, and exploratory nature of the meta-regression analyses.</p><p><strong>The prospero registration: </strong>The review was registered in PROSPERO (CRD420251145641).</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"40 5","pages":"24-38"},"PeriodicalIF":2.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of climatic factors on headache patterns: a 14-year time series analysis of cluster and tension-type headaches in primary care.","authors":"Juan Nicolás Cuenca-Zaldívar, Carmen Corral Del Villar, Silvia García Torres, Rafael Araujo Zamora, Paula Gragera Peña, Tiago José Gomes de Oliveira, Filipa Paisana Ricardo, Erika Meléndez-Oliva, Ada María González-González, Eleuterio A Sánchez-Romero","doi":"10.22514/jofph.2026.045","DOIUrl":"10.22514/jofph.2026.045","url":null,"abstract":"<p><strong>Background: </strong>Weather-related influences on pain and neurological symptoms are widely discussed in biometeorology. However, the long-term impact of climatic variables on primary care headache consultations remains unclear. This study aimed to examine whether climatic variables are associated with consultations for cluster headaches, tension-type headaches (TTH), and unspecified headaches over 14 years.</p><p><strong>Methods: </strong>Data (2010-2023) were extracted from medical records using International Classification of Primary Care, Second Edition (ICPC-2) codes. Meteorological variables (temperature, rainfall, wind direction, barometric pressure, and sunshine hours) were obtained from the State Meteorological Agency. Time-series analyses used Exponential Smoothing State Space Model with External Regressors (ETSX) and AutoRegressive Integrated Moving Average Models with External Regressors (ARIMAX) using age, sex, and meteorological factors as external regressors. Model accuracy was evaluated using the Root Mean Squared Error (RMSE), Symmetric Mean Absolute Percentage Error (SMAPE), and Mean Absolute Scaled Error (MASE).</p><p><strong>Results: </strong>A total of 5127 headache consultations were analyzed (mean age, 45.0 ± 19.9 years; 68.9% female). ETSX models best fit the overall, unspecified, and cluster headache series, whereas the ARIMAX model provided optimal performance for TTH. Sex was the strongest predictor across all models. In TTH, female sex increased consultations (<i>p</i> < 0.001), whereas higher temperature (<i>p</i> = 0.031) and wind direction (cosine component; <i>p</i> = 0.027) were associated with fewer consultations. For cluster headache, male sex was associated with fewer consultations (<i>p</i> = 0.020), and no climatic variables showed a significant association. Meteorological variables were not independently associated with unspecified headache consultations.</p><p><strong>Conclusions: </strong>Climatic variables showed limited, subtype-specific associations, with only temperature and wind direction independently associated with TTH. No weather variables predicted cluster headache or unspecified consultations. Demographic factors appeared to be more strongly associated with healthcare utilization than climatic variables, although ETSX and ARIMAX models may support forecasting and resource planning.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"40 4","pages":"63-75"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13434138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-cultural adaptation and psychometric validation of the Arabic version of the Orofacial Awakening Symptoms Questionnaire (OFASQ).","authors":"Christelle Haddad, Ziad Azar, Anthony Mathias, Lynn Fayad, Tia Azar, Tylor Cosgrove, Mirna Fawaz, Sahar Obeid, Feten Fekih-Romdhane, Souheil Hallit","doi":"10.22514/jofph.2026.050","DOIUrl":"10.22514/jofph.2026.050","url":null,"abstract":"<p><strong>Background: </strong>Making a measure of orofacial pain available for use among Arabic-speakers might contribute to the development of prevention and therapeutic programs that consider psychosocial and behavioral determinants of the Lebanese population. This study aimed to translate, culturally adapt, and validate the Arabic version of the Orofacial Awakening Symptoms Questionnaire (OFASQ) among Lebanese adults.</p><p><strong>Methods: </strong>A cross-sectional web-based survey was conducted during August-September 2025 and included 427 participants (mean age = 27.5 ± 10.6 years; 56% women). The OFASQ was translated to Arabic using the forward-backward translation protocol.</p><p><strong>Results: </strong>Confirmatory Factor Analysis (CFA) supported a single-factor structure with good fit indices (χ²/<i>df</i> = 2.67, Comparative Fit Index (CFI) = 0.970, Tucker-Lewis Index (TLI) = 0.941, Root Mean Square Error of Approximation (RMSEA) = 0.144 (90% Confidence Interval (CI): 0.086-0.207), and Standardized Root Mean Square Residual (SRMR) = 0.033). Internal consistency was good (Cronbach's α = 0.85). Measurement invariance across gender was established, with females scoring higher than males on the OFASQ. For criterion validity, higher OFASQ scores were significantly associated with worse sleep quality, more insomnia severity, and higher migraine.</p><p><strong>Conclusions: </strong>The Arabic OFASQ displayed reliability, validity, and cultural appropriateness for evaluating orofacial awakening indicators of bruxism and temporomandibular disorders in Arabic-speaking populations, validating its use in both clinical and research settings.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"40 4","pages":"76-83"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13434142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypnosis and relaxation techniques in the management of temporomandibular disorders: a scoping review.","authors":"Estelle Casazza, Benoit Ballester, Maxime Joncour, Yamina Benamara-Tlemsani, Jean-Philippe Ré, Anne Giraudeau","doi":"10.22514/jofph.2026.048","DOIUrl":"10.22514/jofph.2026.048","url":null,"abstract":"<p><p>Temporomandibular disorders (TMD) are common causes of orofacial pain, influenced by psychological and behavioural factors. Non-pharmacological interventions, such as hypnosis and relaxation techniques, have been proposed to modulate pain perception, reduce muscle hyperactivity, and improve coping. However, their role in TMD management remains unclear. We conducted a scoping review to synthesize the available evidence on the use of hypnosis and relaxation interventions in adolescents and adults with TMD. A systematic search of PubMed, Embase, Web of Science, Cochrane Library, PsycINFO, and Google Scholar databases from January 1992 to January 2026 identified a limited number of eligible studies (n = 10), comprising randomized controlled trials and quasi-experimental studies, with substantial methodological heterogeneity in study design. Methodological quality was appraised using a simplified Joanna Briggs Institute tool. Interventions included medical hypnosis, hypnosis combined with cognitive-behavioural therapy, and various relaxation techniques, delivered as stand-alone or adjunctive therapies. Findings for the 661 participants were inconsistent: hypnosis-based interventions suggested potential reductions in pain intensity and psychological distress, whereas relaxation techniques showed mixed results, particularly when compared to standard treatments such as occlusal splints. Methodological appraisal revealed variability in study quality, with three studies at low risk of bias, four at moderate risk, and three at high risk. Overall, the small number of studies and their marked heterogeneity substantially limit the interpretability and comparability of findings, thereby constraining their integration into a robust evidence-based biopsychosocial model for TMD management. Consequently, current evidence remains preliminary and insufficient to support firm clinical recommendations. Nevertheless, these approaches are conceptually aligned with the biopsychosocial model of TMD, and preliminary results suggest that hypnosis and relaxation may represent low-risk adjunctive strategies within multimodal TMD management, particularly for patients with stress-sensitive or centrally sensitized pain profiles. Future well-designed, adequately powered trials with standardized interventions and multidimensional outcomes are needed to clarify their clinical utility.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"40 4","pages":"19-31"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13434141/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Altered locus coeruleus functional connectivity in migraine without aura based on resting-state functional magnetic resonance imaging.","authors":"Wanting Han, Yaxuan Wang, Xiaobin Huang, Fengfang Li, Di Zhang, Yujia Gao, Lindong Liu, Tong Fu, Xinying Wu","doi":"10.22514/jofph.2026.054","DOIUrl":"10.22514/jofph.2026.054","url":null,"abstract":"<p><strong>Background: </strong>Accumulating evidence indicates that the locus coeruleus (LC) plays a pivotal role in pain modulation and related network dysfunction in migraine. This study aimed to examine functional connectivity (FC) between the LC and other brain regions in patients with migraine without aura (MwoA) compared with healthy controls (HCs).</p><p><strong>Methods: </strong>A total of 55 patients with MwoA and 50 age-, sex-, and education-matched HCs underwent resting-state functional magnetic resonance imaging (fMRI). Seed-to-voxel whole-brain FC analysis was performed using the bilateral LC as seed regions. Different clinical and neuropsychological assessments are included. Pearson correlation analysis was used to determine the relationships between altered FC and clinical variables, and receiver operating characteristic (ROC) analysis was further performed to evaluate the discriminatory performance of significant FC measures.</p><p><strong>Results: </strong>Compared with HCs, patients with MwoA exhibited increased FC between the left LC and the right superior temporal gyrus (STG)/left cerebellar posterior lobe (CPL), as well as between the right LC and the left STG/left inferior occipital gyrus (IOG) (<i>p</i> < 0.05). Decreased FC was observed between the bilateral LC and the right superior frontal gyrus (SFG) (<i>p</i> < 0.05). Positive correlations were identified between disease duration and FC of the left LC-right STG connection (<i>p</i> = 0.012, <i>r</i> = 0.341), and between SDS scores and FC of the right LC-left IOG connection (<i>p</i> = 0.011, <i>r</i> = 0.344). ROC analysis demonstrated that FC between the right LC and right SFG had the best discriminatory performance (sensitivity 81.82%, specificity 68.00%).</p><p><strong>Conclusions: </strong>Patients with MwoA exhibited altered LC-related resting-state FC involving brain regions associated with pain processing, sensory integration, and emotional regulation. By separately characterizing the whole-brain connectivity patterns of the bilateral LC, this study extends previous LC-related imaging findings in migraine and provides a more refined description of LC-centered network dysfunction in MwoA.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"40 4","pages":"120-129"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13434137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148671072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quantitative pupillometry as a marker of autonomic dysregulation in vestibular migraine.","authors":"Gokce Saygi Uysal, Zulkuf Kucuktag, Aykut Ozdogan, Mevlut Yilmaz, Tuba Kuz Teksut, Gulce Kirazli","doi":"10.22514/jofph.2026.053","DOIUrl":"10.22514/jofph.2026.053","url":null,"abstract":"<p><strong>Background: </strong>Vestibular migraine (VM) has been associated with altered central sensory processing; however, objective measures of autonomic involvement remain insufficiently characterized. Quantitative pupillometry enables standardized assessment of both static and dynamic pupil responses. This study compared pupillary parameters between patients with VM and healthy controls under controlled illumination conditions.</p><p><strong>Methods: </strong>Seventy participants were enrolled, including 40 patients diagnosed with VM according to the International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria, and 30 age- and sex-matched controls. Bilateral pupillometry was performed using an automated infrared system under scotopic, mesopic, low photopic, high photopic, and resting light conditions. Static pupil diameter and dynamic parameters (including constriction amplitude, latency, duration, velocity, and dilation metrics) were recorded. Between-group comparisons were conducted using parametric or nonparametric tests, as appropriate based on the data distribution.</p><p><strong>Results: </strong>No significant differences were observed between groups in mean pupil diameter across illumination conditions (all <i>p</i> > 0.05). Dynamic pupillary parameters also did not differ significantly between the study groups. However, both groups demonstrated mild right-to-left asymmetry in static measurements, with a statistically significant interocular difference observed in the VM group under high-photopic conditions (<i>p</i> = 0.001). Dynamic asymmetries were minimal and not clinically meaningful.</p><p><strong>Conclusions: </strong>Interictal static and dynamic pupillary parameters did not differ significantly between patients with VM and healthy controls. Although minor light-dependent asymmetries were observed, their clinical significance remains uncertain. Further studies incorporating longitudinal designs and multimodal autonomic assessments are warranted to clarify the relationship between autonomic function and VM.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"40 4","pages":"110-119"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13434144/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of dizziness in patients with temporomandibular disorders: a systematic review and meta-analysis.","authors":"Rayan Ibrahim H Binduhayyim, Sunil Kumar Vaddamanu, Masroor Ahmed Kanji, Rajesh Vyas, Marco Di Blasio, Gabriele Cervino, Maria Maddalena Marrapodi, Giuseppe Minervini","doi":"10.22514/jofph.2026.044","DOIUrl":"10.22514/jofph.2026.044","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular disorders (TMDs) are characterised by pain and dysfunction in the temporomandibular joints and surrounding muscles. Dizziness is a frequent symptom reported by TMD patients, but the prevalence of dizziness in this population remains unclear.</p><p><strong>Methods: </strong>A systematic review and meta-analysis was conducted to identify relevant studies assessing the prevalence of dizziness in TMD patients. Seven electronic databases were searched using a combination of Boolean operators and Medical Subject Headings (MeSH) keywords to maximise sensitivity and specificity.</p><p><strong>Results: </strong>The meta-analysis revealed a significant association between TMDs and dizziness in descriptive studies (pooled odds ratio (OR): 0.42, 95% confidence interval (CI): 0.20-0.88) but found a non-significant association in analytical studies (pooled OR: 0.55, 95% CI: 0.19-1.59). Heterogeneity was low in analytical studies (0%), while descriptive studies showed higher heterogeneity (96%). The studies included in the review generally reported a significant prevalence of vertigo and other aural symptoms in TMD patients. Some investigations highlighted the value of sociodemographic characteristics and the statistical association between TMD and vestibular symptoms. Furthermore, dizziness was quantitatively attributed to TMDs in some studies, while others reported a correlation between TMDs and otolaryngological symptoms.</p><p><strong>Conclusions: </strong>The current review demonstrated that TMDs are associated with increased dizziness and vestibular symptoms, particularly in descriptive research. A causal relationship could not be established due to the heterogeneity and observational nature of the studies included. These findings emphasise the need for careful interpretation and recommend prospective studies to clarify the relationship. When diagnosing and treating TMD patients, clinicians should consider these symptoms together.</p><p><strong>The prospero registration: </strong>CRD420251026371.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"40 4","pages":"52-62"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13434147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of psychological stress on masticatory muscle electromyography-a scoping review.","authors":"Alexander Weden, Michail Koutris, Hedwig van der Meer","doi":"10.22514/jofph.2026.047","DOIUrl":"10.22514/jofph.2026.047","url":null,"abstract":"<p><p>Temporomandibular disorders (TMDs) are the second most common reason for orofacial pain with myalgia being the most prevalent diagnosis. Overuse of the masticatory muscles and the presence of stress are both risk factors for myalgia. The extent to which these risk factors interact remains unclear, including whether psychological stress contributes to increased masticatory muscle activity. The purpose of this scoping review was to identify, examine, and map the available literature exploring the relationship between psychological stress and masticatory muscle electromyography (EMG). Pre-clinical and clinical studies that studied adults with or without TMD who were exposed to psychological stress and had masticatory muscle electromyography recordings were included. The electronic databases CINAHL, EMBASE, Medline, and PsycINFO were searched in March 2025. Using a pre-defined data extraction sheet, basic study information and specific results regarding the research question were extracted. These were analysed and the results were described based on the type of study (pre-clinical <i>vs.</i> clinical), as well as the type of stress (experimental <i>vs.</i> clinical). Following screening, 38 studies (published between 1971 and 2025) were included: 29 clinical experimental studies, 3 cross-sectional studies and 6 pre-clinical studies. All pre-clinical and cross-sectional studies demonstrated that psychological stress increased masticatory muscle EMG. Among the clinical studies, 25 of the 29 studies reported that psychological stress increased masticatory muscle EMG. Psychological stress consistently increased masticatory muscle EMG in both human and animal models, although some caution is warranted given the paucity of manipulation checks in the included studies. Putative biological mechanisms are discussed herein. A trend towards greater EMG amplitude in response to stress in patients with TMD compared to healthy controls was demonstrated. Given the high prevalence of psychological stress in Western populations, these findings argue that the presence of psychological stress should be consistently evaluated when assessing patients with TMD.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"40 4","pages":"9-18"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13434148/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global, regional, and national burden of migraine in postmenopausal women: a 32-year analysis from the global burden of disease study 1990-2021.","authors":"Yufeng Ding, Kegang Cao, Nannan Qian, Yulong Yang, Xuran Zhang","doi":"10.22514/jofph.2026.052","DOIUrl":"10.22514/jofph.2026.052","url":null,"abstract":"<p><strong>Background: </strong>Migraine is a major cause of disability globally, yet its epidemiological impact on postmenopausal women (aged ≥55 years) is not well understood. This study aims to fill this knowledge gap by analyzing long-term trends in migraine burden from 1990 to 2021.</p><p><strong>Methods: </strong>Data from the Global Burden of Disease (GBD) 2021 study were utilized to estimate prevalence, incidence, and disability-adjusted life years (DALYs), stratified by age group, Socio-demographic Index (SDI), and geographical region. Temporal trends were assessed using the estimated annual percentage change (EAPC), while socioeconomic inequalities were evaluated through the Slope Index of Inequality (SII) and Concentration Index (CIX).</p><p><strong>Results: </strong>The number of prevalent cases of migraine among postmenopausal women increased by 118.3% globally, rising from 55.29 million to 120.68 million between 1990 and 2021. Age-standardized rates (ASRs) in this population displayed contrasting trends: while age-standardized prevalence and incidence rates experienced slight increases (EAPC: 0.07-0.17), the age-standardized DALY rate (ASDR) remained stable. Middle-SDI regions faced the highest absolute burden of migraine in postmenopausal women and showed the most rapid growth in ASRs. Inequality analyses highlighted persistent socioeconomic disparities, revealing significant efficiency gaps in health resource utilization in high-SDI countries.</p><p><strong>Conclusions: </strong>This study highlights the increasing absolute burden of migraine among postmenopausal women, despite stable age-standardized rates. This underscores the need for context-specific interventions across SDI strata to reduce health inequities and optimize resource allocation in migraine care.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"40 4","pages":"97-109"},"PeriodicalIF":2.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13434146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}