Aalia Karamat, Jared G Smith, Lydia Nabil Fouad Melek, Tara Renton
{"title":"Psychologic Impact of Chronic Orofacial Pain: A Critical Review.","authors":"Aalia Karamat, Jared G Smith, Lydia Nabil Fouad Melek, Tara Renton","doi":"10.11607/ofph.3010","DOIUrl":"10.11607/ofph.3010","url":null,"abstract":"<p><strong>Aims: </strong>To explore the prevalence of clinically significant anxiety and depression in adult patients with chronic orofacial pain (COFP) conditions.</p><p><strong>Methods: </strong>A systematic online search of the Medline (PubMed) and Ovid databases was performed for articles published from 2006 to 2019. Observational studies- including cross-sectional, case-control, and case series-and longitudinal prospective studies were included. A total of 118 articles were selected for inclusion, and the prevalence rates of clinically significant anxiety and depression were summarized.</p><p><strong>Results: </strong>Most studies focused on temporomandibular disorder (TMD) pain and less often on neuropathic COFP conditions. Prevalence rates varied widely across studies according to OFP condition and assessment measure; most questionnaire-based assessments yielded rates of clinically significant depression and anxiety in, respectively, 40% to 60% and 40% to 65% of individuals with TMD and in 20% to 50% and 25% to 55% of patients with neuropathic, mixed, or idiopathic/atypical COFP conditions. Rates of anxiety and depression were lower in studies using diagnostic instruments and in TMD studies with nonpatient samples. Most controlled studies showed a higher prevalence of anxiety and depression in individuals with COFP than in those without. Higher COFP pain levels and the presence of comorbid conditions such as migraines or widespread pain increased the likelihood of anxiety and/or depressive symptoms in individuals.</p><p><strong>Conclusion: </strong>Clinically significant anxiety and depression were commonly observed in patients with COFP, were present at higher rates than in pain-free participants in controlled studies, and were closely linked to pain severity. More research is needed to evaluate the psychologic impact of multiple COFP conditions in an individual and the prevalence of precondition psychologic morbidity.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"36 2","pages":"103-140"},"PeriodicalIF":2.5,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40596598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Anxiety Levels in Children and Their Mothers and Appearance of Sleep Bruxism in Turkish Children and Associated Risk Factors: A Cross-Sectional Study.","authors":"İffet Yazıcıoğlu, Perihan Çam Ray","doi":"10.11607/ofph.3011","DOIUrl":"10.11607/ofph.3011","url":null,"abstract":"<p><strong>Aims: </strong>To evaluate the anxiety of children and their mothers in relation to sleep bruxism (SB) and associated risk factors.</p><p><strong>Methods: </strong>A total of 96 children (48 with and 48 without bruxism) and their mothers participated in this study. A form with comprehensive history and oral and parafunctional habits associated with SB was used. Screen for Child Anxiety and Related Disorders (SCARED) was used to measure anxiety in children. The anxiety levels of the mothers were evaluated with the State-Trait Anxiety Inventory (STAI). SPSS version 21.0 was used for the analyses. Chi-square test was used to compare categorical data. Student t test or Mann-Whitney U test was used for the comparison of continuous data, and multiple logistic regression model was applied to detect the real factors associated with SB.</p><p><strong>Results: </strong>The comparisons of SCARED total (P = .005), factor 3 (separation anxiety; P = .015), factor 4 (social anxiety; P = .011) and factor 5 (school fear; P = .005) showed significant differences between groups. State anxiety scores of the mothers were significantly higher in the bruxism group (P < .001). Statistically significant differences were seen for learning/behavioral/anger problems, mouth breathing, snoring, bad breath, parasitic infections, sleep difficulty, chewing a pen or pencil, and sleeping in their own room (P < .05). The real risk factors associated with SB were learning/behavioral/anger problems, an experience causing stress, snoring, and increased anxiety levels of mothers and children.</p><p><strong>Conclusion: </strong>Elevated anxiety levels of mother or children, learning/behavioral/anger problems, experience causing stress, and snoring increased the risk of having SB in children.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"36 2","pages":"147-154"},"PeriodicalIF":2.5,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40596600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sowmya Ananthan, Amey G Patil, Deepika Jaiswal, Cibele Nasri-Heir, Gary M Heir, Rafael Benoliel
{"title":"Sensory Changes Related to Dental Implant Placement: A Scoping Review.","authors":"Sowmya Ananthan, Amey G Patil, Deepika Jaiswal, Cibele Nasri-Heir, Gary M Heir, Rafael Benoliel","doi":"10.11607/ofph.3027","DOIUrl":"10.11607/ofph.3027","url":null,"abstract":"<p><strong>Aims: </strong>To perform a scoping review of the literature to elucidate the occurrence of nerve damage related to dental implant placement and the factors causing the sensory changes.</p><p><strong>Methods: </strong>An extensive electronic search was conducted using the Cochrane Library, Medline via Ovid, PubMed, Wiley Online, Science Direct, CINAHL, and the Google Scholar databases from the year 1950 to 2020.</p><p><strong>Results: </strong>The search resulted in 1,067 articles, out of which 76 were selected for this review. The articles were categorized as literature review articles, retrospective studies, prospective studies, and case series/case reports. Altogether, 2,526 subjects were assessed retrospectively, with 5.27% transient and 1.39% persistent sensory changes, and a cohort of 2,750 subjects were followed prospectively, with 6.22% transient and 1.31% persistent sensory changes. A total of 336 subjects were enrolled in various case reports and case series, with 5.95% transient sensory changes and 84.52% persistent neurosensory changes. The articles included were not of high quality and have variations in their study designs and reporting procedures, with limited sensory change data to include in this study.</p><p><strong>Conclusion: </strong>After surgical placement of dental implants in 5,612 patients, the incidence of transient sensory changes was 5.63%, and the incidence of persistent sensory changes was 6.33%. Factors affecting the incidence were: mandibular location of the implant, with the inferior alveolar nerve as the most commonly affected nerve. The common symptoms reported were paresthesia and dysesthesia. Age and gender were among other factors, for which data were not available in all the articles.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"36 2","pages":"165-186"},"PeriodicalIF":1.9,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586583/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40613033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ian A Boggero, Hannah M Pickerill, Christopher D King
{"title":"Fatigue in Adults with Chronic Arthralgia/Myalgia in the Temporomandibular Region: Associations with Poor Sleep Quality, Depression, Pain Intensity, and Future Pain Interference.","authors":"Ian A Boggero, Hannah M Pickerill, Christopher D King","doi":"10.11607/ofph.2944","DOIUrl":"10.11607/ofph.2944","url":null,"abstract":"<p><strong>Aims: </strong>To examine associations between fatigue and poor sleep quality, depression symptoms, and pain intensity in an adult population with chronic arthralgia/myalgia in the temporomandibular region and to test whether fatigue predicted future pain-related interference above and beyond these other constructs.</p><p><strong>Methods: </strong>The sample included 40 participants with chronic arthralgia and/or myalgia in the temporomandibular region and 21 healthy controls. Participants self-reported fatigue (PROMIS fatigue score), sleep quality (PSQI), depression symptoms (PROMIS depression score), and average pain intensity and completed four weekly surveys of pain-related interference with daily activities.</p><p><strong>Results: </strong>The chronic arthralgia/myalgia group reported greater fatigue than healthy controls (t = 4.85, P < .001). Fatigue was significantly correlated with poor sleep quality (r = .46), higher depression symptoms (r = .41), and higher pain intensity (r = .46) in the chronic arthralgia/myalgia group, and these three variables together explained 39% of variance in fatigue. Greater fatigue-above and beyond sleep quality, depression symptoms, and average pain intensity-was associated with a higher average level of pain-related interference (β = 0.56, t score = 3.30, P = .002) over the following month. Depression symptoms, poor sleep quality, and pain intensity did not significantly predict pain interference above and beyond fatigue (all P > .05).</p><p><strong>Conclusion: </strong>The results suggest that fatigue is a clinically relevant symptom distinct from depression, poor sleep quality, or pain intensity and may be related to worse pain outcomes over the following month in adults with chronic temporomandibular arthralgia/myalgia. Clinicians should assess, monitor, and treat fatigue to the best of their abilities when working with this population.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"36 2","pages":"155-163"},"PeriodicalIF":2.5,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40613032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Double-Puncture Versus Single-Puncture Arthrocentesis: A Randomized Controlled Trial with 3 Years of Follow-Up.","authors":"Eduardo Grossmann, Rodrigo Lorenzi Poluha","doi":"10.11607/ofph.3074","DOIUrl":"10.11607/ofph.3074","url":null,"abstract":"<p><strong>Aims: </strong>To compare the clinical effectiveness of conventional double-puncture vs single-puncture type 2 arthrocentesis for management of temporomandibular joint (TMJ) disc displacement without reduction (DDWOR) after 3 years of follow-up.</p><p><strong>Methods: </strong>A total of 26 patients with DDWOR were randomly and blindly allocated into two treatment groups (n = 13 each): group 1 = conventional double-puncture arthrocentesis; group 2 = single-puncture type 2 arthrocentesis. Data on gender, side of painful joint complaint, age (years), duration of joint pain (months), maximum interincisal distance (MID, mm), and pain intensity (self-reported with a 0-10 visual analog scale [VAS]) were collected. VAS scores and MID were measured before (baseline) and 3 years after (final) the arthrocentesis.</p><p><strong>Results: </strong>Twenty-three patients completed the study (group 1, n = 11; group 2, n = 12). Both techniques resulted in significantly reduced VAS scores and increased MID (P = .001) after the 3 years of follow-up; however, there were no statistically significant differences between techniques (P > 0.05).</p><p><strong>Conclusion: </strong>The two arthrocentesis methods tested were both effective in reducing VAS scores and increasing MID in patients with DDWOR.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"36 2","pages":"141-146"},"PeriodicalIF":2.5,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40596599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cibele Dal Fabbro, Philippe Harris, Eric Dufresne, Alberto Herrero Babiloni, Pierre Mayer, Houda Bahig, Edith Filion, Felix Nguyen, Julien Ghannoum, Matthieu Schmittbuhl, Gilles Lavigne
{"title":"Orofacial Pain and Snoring/Obstructive Sleep Apnea in Individuals with Head and Neck Cancer: A Critical Review.","authors":"Cibele Dal Fabbro, Philippe Harris, Eric Dufresne, Alberto Herrero Babiloni, Pierre Mayer, Houda Bahig, Edith Filion, Felix Nguyen, Julien Ghannoum, Matthieu Schmittbuhl, Gilles Lavigne","doi":"10.11607/ofph.3176","DOIUrl":"10.11607/ofph.3176","url":null,"abstract":"<p><strong>Aims: </strong>(1) To summarize current knowledge on the prevalence, intensity, and descriptors of orofacial pain and snoring/obstructive sleep apnea (OSA) before and after head and neck cancer (HNC) treatment; and (2) to propose future directions for research.</p><p><strong>Methods: </strong>The median prevalence for each condition was estimated from the most recent systematic reviews (SRs) and updated with new findings retrieved from the PubMed, Web of Science, Embase, and Cochrane databases up to December 2021.</p><p><strong>Results: </strong>The prevalence of HNC pain seems relatively stable over time, with a median of 31% before treatment in three studies to a median of 39% at 1 month to 16 years after treatment in six studies. HNC pain intensity remains mild to moderate. There was a threefold increase in temporomandibular pain prevalence after surgery (median 7.25% before to 21.3% after). The data for snoring prevalence are unreliable. The OSA/HNC prevalence seems relatively stable over time, with a median of 72% before treatment in three studies to 77% after treatment in 14 studies.</p><p><strong>Conclusion: </strong>With the exception of temporomandibular pain, the prevalence of HNC pain and OSA seems to be stable over time. Future studies should: (1) compare the trajectory of change over time according to each treatment; (2) compare individuals with HNC to healthy subjects; (3) use a standardized and comparable method of data collection; and (4) assess tolerance to oral or breathing devices, since HNC individuals may have mucosal sensitivity or pain.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"36 2","pages":"85-102"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40596597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matteo Cotta Ramusino, Giulia Perini, Marco Capelli, Gloria Vaghi, Roberto Fogari, Daniele Bosone, Alfredo Costa
{"title":"Potential Contribution of Hypertension to Evolution of Chronic Migraine and Related Mechanisms.","authors":"Matteo Cotta Ramusino, Giulia Perini, Marco Capelli, Gloria Vaghi, Roberto Fogari, Daniele Bosone, Alfredo Costa","doi":"10.11607/ofph.3174","DOIUrl":"10.11607/ofph.3174","url":null,"abstract":"<p><strong>Aims: </strong>To investigate the potential contributions of diastolic and systolic blood pressure (BP) and the circadian rhythm of BP to chronic migraine evolution.</p><p><strong>Methods: </strong>This cross-sectional study included four groups of patients selected based on migraine frequency (high frequency ≥ 10 days per month and low frequency < 10) and on the presence of hypertension. Among-group and pairwise comparisons were carried out to investigate potential neurophysiologic differences in the cerebral vessel reactivity to a nitroglycerin test, in autonomic balance (tilting test), and BP circadian rhythm.</p><p><strong>Results: </strong>A more marked decrease in cerebral blood flow velocity was observed in hypertensive high-frequency migraineurs compared to all other groups (P = .037). Moreover, a smaller decrease in vagal tone was recorded in the orthostatic position in hypertensive subjects, whether they were high- (P = .032) or low-frequency migraineurs (P = .014), with a consistently higher vagal to sympathetic tone ratio (P = .033). Finally, in nonhypertensive subjects, a higher but not significant prevalence of systolic nondippers was detected in high-frequency migraineurs (67%) compared to low-frequency subjects (25%; P = .099).</p><p><strong>Conclusion: </strong>These findings suggest that hypertension may contribute to the chronic evolution of headache with mechanisms shared with migraine; ie, vascular tone alteration and autonomic dysregulation.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"36 3-4","pages":"221–228"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10353012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy and Safety of Melatonin as Prophylaxis for Migraine in Adults: A Meta-analysis.","authors":"Haridas Mundot Puliappadamb, Rituparna Maiti, Archana Mishra, Monalisa Jena, Biswa Ranjan Mishra","doi":"10.11607/ofph.3211","DOIUrl":"10.11607/ofph.3211","url":null,"abstract":"<p><strong>Aims: </strong>To evaluate the efficacy and safety of melatonin for migraine prophylaxis in adults.</p><p><strong>Methods: </strong>After a comprehensive literature search in the MEDLINE, Cochrane Database, and International Clinical Trial Registry Platform databases, reviewers extracted data from three relevant articles. PRISMA guidelines were followed in the selection, analysis, and reporting of the findings. Quality assessment was performed using the Cochrane risk of bias assessment tool. A random-effects model was used to estimate the effect size, and meta-regression was performed for variables with a likely influence on effect size. Subgroup analysis was performed based on the comparison used in the included studies.</p><p><strong>Results: </strong>Melatonin therapy in migraine was associated with a significantly higher responder rate when compared to both placebo and standard therapy (OR = 1.84; 95% CI: 1.08 to 3.14; P = .03). The results of the meta-analyses indicated that melatonin can achieve a significant reduction in frequency of migraine attacks (MD = 1.00; 95% CI: 0.02 to 1.98; P = .04), migraine attack duration (MD = 5.02; 95% CI: 0. 91 to 9.13; P = .02), use of analgesics (MD = 1.43; 95% CI: 0.38 to 2.48; P = .008), and migraine severity (MD = 1.93; 95% CI: 1.23 to 2.63; P < .0001) over placebo, but had no significant effects in comparison to amitriptyline or valproate. There was no significant difference in the occurrence of common adverse drug reactions, such as drowsiness and fatigue, between the melatonin group and the comparison groups.</p><p><strong>Conclusions: </strong>Melatonin showed a beneficial prophylactic role in migraine, with a better responder rate in comparison to placebo in reducing migraine severity, mean attack duration, mean attack frequency, and analgesic use, but did not show significant effects in comparison to amitriptyline or valproate.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"36 3-4","pages":"207–219"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10413313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolina Venda Nova, Joanna M Zakrzewska, Richeal Ni Riordain, Sarah R Baker
{"title":"\"They Could Have Cut My Head Off and I Wouldn't Have Cared\"-A Qualitative Study of Patient Experiences and the Impact of Trigeminal Neuralgia.","authors":"Carolina Venda Nova, Joanna M Zakrzewska, Richeal Ni Riordain, Sarah R Baker","doi":"10.11607/ofph.3110","DOIUrl":"https://doi.org/10.11607/ofph.3110","url":null,"abstract":"<p><strong>Aims: </strong>To understand, from the patient perspective, the meaning of living with trigeminal neuralgia (TN) and what the patient-desired outcomes of treatment are.</p><p><strong>Methods: </strong>A qualitative study involving focus group work with 14 participants with a diagnosis of TN was conducted. The discussions were recorded and transcribed verbatim and analyzed using framework analysis.</p><p><strong>Results: </strong>Four themes and 14 subthemes were identified. Theme 1 reflects the uncertainty about TN etiology and prognosis; theme 2 includes descriptions of the mental, social, and physical impacts of TN that contrast with coping mechanisms developed over time; theme 3 reflects participants' views of what a successful treatment means and the specific outcomes they expect following treatment, as well as patient willingness to self-manage their conditions while supported; and theme 4 highlights the importance of appropriate and timely access to health care and the importance of peer support.</p><p><strong>Conclusion: </strong>This study confirms the need to move beyond the biologic models of disease to patient-centered care and research approaches.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"36 3-4","pages":"189–205"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10413312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yasmin Fadol, Yoly Gonzalez, Heidi C Crow, W D McCall
{"title":"Immediate Effect of Ultrasound on Bilateral Masseter Myalgia: A Randomized Dose-Response Clinical Trial.","authors":"Yasmin Fadol, Yoly Gonzalez, Heidi C Crow, W D McCall","doi":"10.11607/ofph.2836","DOIUrl":"10.11607/ofph.2836","url":null,"abstract":"<p><strong>Aims: </strong>(1) To determine the dose-response relationship of therapeutic ultrasound for TMD-related pain in the masseter muscle among four doses comprised of two intensities (0.4 W/cm<sup>2</sup> and 0.8 W/cm<sup>2</sup>) and two duty cycles (50% and 100%); and (2) to determine if therapeutic ultrasound applied to the masseter muscle would elicit a segmental effect on the ipsilateral temporalis muscle.</p><p><strong>Methods: </strong>A total of 28 adult women with bilateral myalgia were randomly allocated to one of the four intervention doses. Therapeutic ultrasound was applied on each side of the masseter sequentially for 5 minutes. The following outcomes were measured before and immediately after each intervention: self-reported pain score, pressure pain thresholds for the masseter and temporalis muscles, and intraoral temperature adjacent to the treated masseter.</p><p><strong>Results: </strong>Self-reported pain scores showed neither significant main effects nor significant interaction among the intensity or duty cycle doses (all P > .05). The change in the pressure pain threshold of the masseter showed a significant interaction (P = .02) attributed to the 0.4 W/cm<sup>2</sup> and 100% duty cycle dose. Intraoral temperature was significantly increased and associated with the duty cycle (P = .01). A significant segmental effect of the pressure pain threshold of the temporalis was found for intensity (P = .01).</p><p><strong>Conclusion: </strong>There was an increase in the pressure pain threshold of the painful masticatory muscles and an increase in intraoral temperature adjacent to the treated area immediately after the use of ultrasound at 0.4 W/cm<sup>2</sup> with a 100% duty cycle.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"36 3-4","pages":"263–271"},"PeriodicalIF":2.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10586568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10413314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}