Giancarlo De la Torre Canales, Rodrigo Lorenzi Poluha, Yeidi Natalia Alvarez Pinzón, Paulo César Rodrigues Conti, Daniele Manfredini, Alfonso Sánchez-Ayala, Célia Marisa Rizzatti-Barbosa
{"title":"Effects of Botulinum Toxin Type A on the Psychosocial Features of Myofascial Pain TMD Subjects: A Randomized Controlled Trial.","authors":"Giancarlo De la Torre Canales, Rodrigo Lorenzi Poluha, Yeidi Natalia Alvarez Pinzón, Paulo César Rodrigues Conti, Daniele Manfredini, Alfonso Sánchez-Ayala, Célia Marisa Rizzatti-Barbosa","doi":"10.11607/ofph.2917","DOIUrl":"https://doi.org/10.11607/ofph.2917","url":null,"abstract":"<p><strong>Aims: </strong>To determine the effects of botulinum toxin type A (BoNT-A) on the psychosocial features of patients with masticatory myofascial pain (MFP).</p><p><strong>Methods: </strong>A total of 100 female subjects diagnosed with MFP were randomly assigned into five groups (n = 20 each): oral appliance (OA); saline solution (SS); and three groups with different doses of BoNT-A. Chronic pain-related disability and depressive and somatic symptoms were evaluated with the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) Axis II instruments at baseline and after 6 months of treatment. Differences in treatment effects within and between groups were compared using chi-square test, and Characteristic Pain Intensity (CPI) was compared using two-way ANOVA. A 5% probability level was considered significant in all tests.</p><p><strong>Results: </strong>Most patients presented low pain-related disability (58%), and 6% presented severely limiting, high pain-related disability. Severe depressive and somatic symptoms were found in 61% and 65% of patients, respectively. In the within-group comparison, BoNT-A and OA significantly improved (P < .001) scores of pain-related disability and depressive and somatic symptoms after 6 months. Only the scores for pain-related disability changed significantly over time in the SS group. In the between-group comparison, BoNT-A and OA significantly improved (P < .05) scores of all variables at the final follow-up when compared to the SS group. No significant difference was found between the BoNT-A and OA groups (P > .05) for all assessed variables over time.</p><p><strong>Conclusion: </strong>BoNT-A was at least as effective as OA in improving pain-related disability and depressive and somatic symptoms in patients with masticatory MFP.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"35 4","pages":"288-296"},"PeriodicalIF":2.5,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39651186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Experiences and Outcomes of Attending a Facial Pain Management Program: A Qualitative Study.","authors":"Christian Ainsley, Alison Bradshaw, Calum Murray, Nathan Goss, Samantha Harrison, Rajiv Chawla","doi":"10.11607/ofph.2858","DOIUrl":"https://doi.org/10.11607/ofph.2858","url":null,"abstract":"<p><strong>Aims: </strong>To understand the experiences of patients diagnosed with chronic facial pain (CFP) who attended a specialist facial pain management program (PMP); specifically, to explore how they experienced attending the facial PMP itself and how they felt it impacted their management of CFP.</p><p><strong>Methods: </strong>Qualitative methodology and focus groups were used to gather patients' views and experiences of attending a facial PMP. Two focus groups were conducted for patients who had all completed the facial PMP. Discussions were recorded and transcribed. Data were then analyzed using thematic analysis to establish key themes relating to participants' experiences of the facial PMP.</p><p><strong>Results: </strong>Thematic analysis identified three main themes, with numerous subthemes within them. The theme \"psychologic change\" had subthemes of self-compassion, acceptance, and reflection. The theme \"behavioral change\" contained subthemes of re-engagement with valued activity, medication, and communication. The theme \"structure and process\" contained subthemes of concentration, need for one-on-one time with the clinician, meeting others, and not enough time (clinical and nonclinical).</p><p><strong>Conclusion: </strong>Facial PMPs may provide a valuable treatment to support long-term coping and adaptation for patients with CFP. Positive changes to coping include both psychologic and behavioral elements. Further research is necessary to clarify how group-based facial PMPs should be structured and delivered.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"35 3","pages":"208-217"},"PeriodicalIF":2.5,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39486226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrew Young, Samantha Gallia, John F Ryan, Atsushi Kamimoto, Olga A Korczeniewska, Mythili Kalladka, Junad Khan, Noboru Noma
{"title":"Diagnostic Tool Using the Diagnostic Criteria for Temporomandibular Disorders: A Randomized Crossover-Controlled, Double-Blinded, Two-Center Study.","authors":"Andrew Young, Samantha Gallia, John F Ryan, Atsushi Kamimoto, Olga A Korczeniewska, Mythili Kalladka, Junad Khan, Noboru Noma","doi":"10.11607/ofph.3008","DOIUrl":"https://doi.org/10.11607/ofph.3008","url":null,"abstract":"<p><strong>Aims: </strong>To assess the speed and accuracy of a checklist user interface for the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD).</p><p><strong>Methods: </strong>A diagnostic tool formatted as a checklist was developed and compared to an existing diagnostic tool, the DC/TMD diagnsostic decision trees. Both types of tools use the DC/TMD and were tested by dental students, interns, and residents in the USA and Japan for diagnosis of hypothetical patients. The comparisons were done in a randomized, crossover, controlled, double-blinded trial.</p><p><strong>Results: </strong>Overall, subjects using the experimental tool answered 25% more correct diagnoses (P < .001) and missed 27% fewer diagnoses (P < .01). They were also able to finalize their diagnoses faster than those using the control tool, in 16% less time (P < .05). The difference in accuracy was more pronounced in complex cases, while the difference in speed was more pronounced in simple cases.</p><p><strong>Conclusion: </strong>This checklist is an alternative user interface for the DC/TMD.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"35 3","pages":"241-252"},"PeriodicalIF":2.5,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39486124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Commentary: Temporomandibular Disorders: Priorities for Research and Care. A New Milestone for the Specialty of Orofacial Pain","authors":"R. Ohrbach, C. Greene","doi":"10.11607/ofph.2021.3.commentary","DOIUrl":"https://doi.org/10.11607/ofph.2021.3.commentary","url":null,"abstract":"","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"24 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78455624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"NASEM Announcement: Recently Released Report by Major Scientific Academy Proposes Significant Changes in Understanding and Managing Temporomandibular Disorders","authors":"C. Greene, J. Kusiak, Terrie Cowley, A. Cowley","doi":"10.11607/ofph.2021.3.announcement","DOIUrl":"https://doi.org/10.11607/ofph.2021.3.announcement","url":null,"abstract":"","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"29 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76359060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editorial: Managing Orofacial Pain: Co-Designing The Way Forward","authors":"C. Peck","doi":"10.11607/ofph.2021.3.e","DOIUrl":"https://doi.org/10.11607/ofph.2021.3.e","url":null,"abstract":"","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"3 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89951467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marco Cabras, Alessio Gambino, Roberto Broccoletti, Simona De Paola, Savino Sciascia, Paolo G Arduino
{"title":"Effectiveness of Nonpharmacologic Treatments of Burning Mouth Syndrome: A Systematic Review.","authors":"Marco Cabras, Alessio Gambino, Roberto Broccoletti, Simona De Paola, Savino Sciascia, Paolo G Arduino","doi":"10.11607/ofph.2868","DOIUrl":"https://doi.org/10.11607/ofph.2868","url":null,"abstract":"AIMS\u0000To assess the efficacy of nonpharmacologic treatments for burning mouth syndrome (BMS).\u0000\u0000\u0000METHODS\u0000PubMed, Scopus, Web of Science, and the Cochrane Central Register of Controlled Trials were systematically searched. Reference lists from the latest systematic reviews (2015 to 2020) on BMS treatment in the PubMed, Scopus, Web of Science, and Cochrane Library databases were also scrutinized. Randomized controlled trials (RCTs) or clinical controlled trials (CCTs) in English were considered eligible. Trials on photobiomodulation were excluded to avoid redundancy with recent publications. Risk of bias was established through the Cochrane Risk of Bias tool for RCTs and the Risk of Bias in Nonrandomized Studies of Interventions (ROBINS-I) tool for CCTs.\u0000\u0000\u0000RESULTS\u0000This review included 27 RCTs and 6 open clinical trials (OCTs) describing 14 different nonpharmacologic interventions. Eleven trials experimented with 600 to 800 mg/day of alpha-lipoic acid for 30 to 120 days, with 7 placebo-controlled studies showing significant pain relief. Four trials tested topical and systemic capsaicin for 7 to 30 days, with 2 placebo-controlled studies revealing significant efficacy. Four of the 5 trials testing acupuncture offered favorable evidence of pain relief. Two trials reported significant pain relief after a 2- to 3-month regimen with tongue protectors and showed no difference after aloe vera addition. Short-term pain relief was reported in anecdotal placebo-controlled trials deploying tocopherol, catuama, ultramicronized palmitoylethanolamide, group psychotherapy, cognitive therapy, and repetitive transcranial magnetic stimulation of the prefrontal cortex. Most therapies were safe.\u0000\u0000\u0000CONCLUSION\u0000Evidence was collected from highly biased, short-term, heterogenous studies mainly focused on BMS-related pain, with scarce data on quality of life, psychologic status, dysgeusia, and xerostomia. Long-term effectiveness of nonpharmacologic treatments should be further investigated, with a more rigorous, bias-proof study design.","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"35 3","pages":"175-198"},"PeriodicalIF":2.5,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39486223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isabel Carreño-Hernández, Juliana Cassol-Spanemberg, Eugenia Rodríguez de Rivera-Campillo, Albert Estrugo-Devesa, José López-López
{"title":"Is Burning Mouth Syndrome a Neuropathic Pain Disorder? A Systematic Review.","authors":"Isabel Carreño-Hernández, Juliana Cassol-Spanemberg, Eugenia Rodríguez de Rivera-Campillo, Albert Estrugo-Devesa, José López-López","doi":"10.11607/ofph.2861","DOIUrl":"https://doi.org/10.11607/ofph.2861","url":null,"abstract":"<p><strong>Aims: </strong>To conduct a systematic review compiling an update on the pathophysiology of burning mouth syndrome (BMS) by reviewing the theories and studies published in the last 5 years that consider BMS a neuropathic disease.</p><p><strong>Methods: </strong>A literature review was carried out in April 2020 on the PubMed database by using the following MeSH terms: \"(burning mouth OR burning mouth syndrome OR burning mouth pain OR sore mouth OR burning tongue OR oral neuropathic pain OR glossodynia OR stomatopyrosis) AND (etiopathogenesis OR etiopathological factors OR etiology).\"</p><p><strong>Results: </strong>The research carried out according to the methodology found 19 case-control studies (1 of which was in vivo) and 1 RCT. Of the 19 included studies, 8 showed an evidence score of 2-; 8 showed 2+; another 2 showed 2++; and 1 showed 1+. Quality studies on this topic are insufficient and heterogenous.</p><p><strong>Conclusion: </strong>In the pathogenesis of BMS, both peripheral and central neuropathies appear to play a pivotal role. Nevertheless, the balance between them varies from case to case and tends to overlap. BMS does not seem to be a result of direct damage to the somatosensory nervous system, but a dysfunction in it and in the brain network.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"35 3","pages":"218-229"},"PeriodicalIF":2.5,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39486227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Juliana Araújo Oliveira Buosi, Sandra Maria Abreu Nogueira, Morgana Pinheiro Sousa, Carla Soraya Costa Maia, Romulo Rocha Regis, Karina Matthes de Freitas Pontes, Leonardo Rigoldi Bonjardim, Lívia Maria Sales Pinto Fiamengui
{"title":"Gluten-Free Diet Reduces Pain in Women with Myofascial Pain in Masticatory Muscles: A Preliminary Randomized Controlled Trial.","authors":"Juliana Araújo Oliveira Buosi, Sandra Maria Abreu Nogueira, Morgana Pinheiro Sousa, Carla Soraya Costa Maia, Romulo Rocha Regis, Karina Matthes de Freitas Pontes, Leonardo Rigoldi Bonjardim, Lívia Maria Sales Pinto Fiamengui","doi":"10.11607/ofph.2823","DOIUrl":"https://doi.org/10.11607/ofph.2823","url":null,"abstract":"<p><strong>Aims: </strong>To evaluate the efficacy of a gluten-free diet (GFD) as a treatment modality for pain management in women with chronic myofascial pain in masticatory muscles.</p><p><strong>Methods: </strong>In this randomized controlled trial, 39 female subjects were evaluated according to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) and divided into three groups: a healthy group (n = 14; mean ± SD age = 34.57 ± 9.14 years); a control group (n = 12; age = 31.50 ± 7.38 years); and an experimental group (n = 13; age 30.00 ± 7.64 years). The outcome variables were: pain intensity, mechanical pain threshold (MPT), and pressure pain threshold (PPT). MPT was performed on the masseter muscle, and PPT was performed on both the masseter and anterior temporalis muscles. A nutritionist prescribed a 4-week individualized GFD for the experimental group. The healthy group was analyzed only initially, whereas the control and experimental groups were analyzed again after 4 weeks. Data were subjected to statistical analysis with a significance level of 5% (one-way analysis of variance followed by Bonferroni post hoc, paired t, Wilcoxon signed rank, Kruskal-Wallis/Dunn, and Pearson chi-square tests).</p><p><strong>Results: </strong>Participants who underwent a GFD showed reduction in pain intensity (P = .006) and an increase in PPT of the masseter (P = .017) and anterior temporalis (P = .033) muscles. The intervention did not influence the MPT of the masseter muscle (P = .26). In contrast, the control group showed no improvement in any parameter evaluated.</p><p><strong>Conclusion: </strong>GFD seemed to reduce pain sensitivity in women with TMD and may be beneficial as an adjunctive therapy for chronic myofascial pain in masticatory muscles; however, further studies in the fields of orofacial pain and nutrition are required.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"35 3","pages":"199-207"},"PeriodicalIF":2.5,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39486225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Headache Attributed to Temporomandibular Disorders: Axis I and II Findings According to the Diagnostic Criteria for Temporomandibular Disorders.","authors":"Shoshana Reiter, Alona Emodi-Perlman, Hanita Kasiel, Waseem Abboud, Pessia Friedman-Rubin, Orit Winocur Arias, Yifat Manor","doi":"10.11607/ofph.2863","DOIUrl":"https://doi.org/10.11607/ofph.2863","url":null,"abstract":"<p><strong>Aims: </strong>To analyze Axis I and II findings of patients diagnosed as having painful temporomandibular disorder (TMD) with headache attributed to TMD (HAattrTMD) in order to assess whether HAattrTMD is associated with a specific Axis I and II profile suggestive of the central sensitization process.</p><p><strong>Methods: </strong>This retrospective study included 220 patients with painful TMD divided into those with (n = 60) and those without (n = 160) HAattrTMD, and the patients were compared for Axis I and II results according to the Diagnostic Criteria for TMD (DC/TMD). A P value < .05 was considered statistically significant.</p><p><strong>Results: </strong>A total of 27.3% of the patients received a diagnosis of HAattrTMD. Myofascial pain with referral was significantly more common in the HAattrTMD group (P < .001), while local myalgia was significantly more common in the non-HAattrTMD group (P < .001). Characteristic pain intensity was significantly higher in the HAattrTMD group (P = .003), which also showed significantly higher levels of depression (P = .002), nonspecific physical symptoms (P = .004), graded chronic pain (P = .008), and pain catastrophizing (P = .013). Nonspecific physical symptoms were positively associated with HAattrTMD (odds ratio [OR] = 1.098, 95% CI = 1.006 to 1.200, P = .037). Local myalgia was negatively associated with HAattrTMD (OR = .295, 95% CI = 0.098 to 0.887, P = .030).</p><p><strong>Conclusions: </strong>Painful TMD patients who report headache in the temple area and are diagnosed as having local myalgia rather than myofascial pain with referral probably do not have HAattrTMD. The diagnosis of HAattrTMD may point to a central sensitization process and possible current/future chronic TMD conditions.</p>","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"35 2","pages":"119-128"},"PeriodicalIF":2.5,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39233266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}