Journal of Oral & Facial Pain and Headache最新文献_第9页

Taste and Pain Response in Burning Mouth Syndrome With and Without Geographic Tongue. 有无地理舌头灼口综合征的味觉和疼痛反应。

IF 2.5 3区医学

Journal of Oral & Facial Pain and Headache Pub Date : 2020-06-01 DOI: 10.11607/ofph.2565

Nan Su, Renee Poon, Cindy Liu, Crystal Dewan, Mark Darling, Miriam Grushka

{"title":"Taste and Pain Response in Burning Mouth Syndrome With and Without Geographic Tongue.","authors":"Nan Su, Renee Poon, Cindy Liu, Crystal Dewan, Mark Darling, Miriam Grushka","doi":"10.11607/ofph.2565","DOIUrl":"https://doi.org/10.11607/ofph.2565","url":null,"abstract":"Aims: To assess the effect of geographic tongue (GT) on taste, salivary flow, and pain characteristics in burning mouth syndrome (BMS) to determine whether GT is a contributing factor to BMS and whether BMS and GT represent similar patient populations.Methods: A retrospective chart study was conducted. Patients with a diagnosis of BMS or BMS/GT were included. Data regarding smell testing, spatial taste-testing, salivary flow, oral pH, and subjective pain rating on a generalized labeled magnitude scale (gLMS) were collected.Results: No significant differences in age, gender, oral pH, smell, or pain were found between groups. Stimulated and unstimulated salivary flow were significantly lower in BMS/GT. Taste responses to all taste stimuli and to ethanol were significantly lower in BMS, with the exception of sour at the fungiform papillae.Conclusion: BMS and BMS/GT present with similar clinical pain phenotype and demographics; however, taste was more intact in BMS/GT, suggesting that GT may be a contributing factor in the development of BMS through a mechanism that does not involve taste.","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"34 3","pages":"217-221"},"PeriodicalIF":2.5,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11607/ofph.2565","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38427135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Can the Measurement of Jaw-Opening Forces Assist in the Diagnosis of Temporomandibular Disorders? 下颌张开力的测量是否有助于颞下颌疾病的诊断?

IF 2.5 3区医学

Journal of Oral & Facial Pain and Headache Pub Date : 2020-06-01 DOI: 10.11607/ofph.2587

Jithendra Ratnayake, Guangzhao Guan, Ajith Polonowita, Kai Chun Li, Andrew R Gray, J Neil Waddell, Carolina Loch, Paul A Brunton

{"title":"Can the Measurement of Jaw-Opening Forces Assist in the Diagnosis of Temporomandibular Disorders?","authors":"Jithendra Ratnayake, Guangzhao Guan, Ajith Polonowita, Kai Chun Li, Andrew R Gray, J Neil Waddell, Carolina Loch, Paul A Brunton","doi":"10.11607/ofph.2587","DOIUrl":"https://doi.org/10.11607/ofph.2587","url":null,"abstract":"Aims: To investigate the effectiveness of a novel jaw-opening-force measuring device as a screening tool to aid in the diagnosis of temporomandibular disorders (TMD).Methods: Symptomatic TMD patients (n = 58) and control TMD-free participants (n = 56) were screened by an oral medicine specialist according to the Diagnostic Criteria for TMD (DC/TMD). TMD patients were divided into three subcategories based on TMD symptoms (myofascial pain, disc displacement, and both combined). Jaw-opening forces were measured in both groups with an adjustable head device connected to a 1,000-N-load cell. Seven attempts were recorded at 10-second intervals by a data-capturing system. The geometric mean force values were obtained after discarding the first and last attempts.Results: TMD-free participants had greater jaw-opening forces than TMD patients both without and with adjustments for age, sex, height, and weight (both P < .001). The geometric mean ± standard deviation values for TMD patients were 18.5 ± 1.62 N and 47.7 ± 1.53 N for TMD-free participants. Differences in jaw-opening forces among the three TMD subcategories were not statistically significant; however, patients with disc displacement (23.7 ± 1.46 N) had greater jaw forces than patients with myofascial pain (17.0 ± 1.74 N) and both myofascial pain and disc displacement (17.0 ± 1.56 N).Conclusion: This study demonstrated that differences in jaw-opening forces could be used as a diagnostic tool for TMD. Future studies should explore the potential of this device to measure improvement in jaw-opening forces following TMD treatment.","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"34 3","pages":"199-205"},"PeriodicalIF":2.5,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11607/ofph.2587","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38330907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

An Operational Clinical Approach in the Diagnosis and Management of Sleep Bruxism: A First Step Towards Validation. 一种可操作的临床方法在诊断和管理睡眠磨牙症:迈向验证的第一步。

IF 2.5 3区医学

Journal of Oral & Facial Pain and Headache Pub Date : 2020-06-01 DOI: 10.11607/ofph.2616

Thays Crosara Abrahão Cunha, Cibele Dal Fabbro, Eduardo Januzzi, Paulo Afonso Cunali, Miguel Meira E Cruz

{"title":"An Operational Clinical Approach in the Diagnosis and Management of Sleep Bruxism: A First Step Towards Validation.","authors":"Thays Crosara Abrahão Cunha, Cibele Dal Fabbro, Eduardo Januzzi, Paulo Afonso Cunali, Miguel Meira E Cruz","doi":"10.11607/ofph.2616","DOIUrl":"https://doi.org/10.11607/ofph.2616","url":null,"abstract":"Exacerbation of nighttime sleep-related oromotor activity is often recognized as a relevant clinical entity commonly known as sleep bruxism (SB). Many pragmatic issues about SB diagnosis and management remain controversial. Therefore, within a critical review of the literature, this article proposes an operational clinical approach for SB diagnosis and management, with a focus on three comorbidities frequently occurring in relation to sleep: obstructive sleep apnea (OSA), gastroesophageal reflux disease (GERD), and insomnia. In the absence of any comorbidities, and if clinically justified, short-term medication and/or splints may be considered. If a comorbid condition is suspected, then the patient should be screened for OSA, GERD, and insomnia. For OSA screening, the Epworth Sleepiness Scale, STOP-Bang, and NoSAS questionnaires are available validated tools. For GERD screening, a positive patient report, whether associated or not with clinical signs and symptoms of heartburn and/or regurgitation, can be tested. For insomnia screening, report of difficulties initiating or maintaining sleep or of early morning awakening more than three times a week may be useful for diagnosis clarification. An adequate clinical approach for comorbid SB requires that both SB and the related comorbid condition be properly assessed and managed. Very often, improvement of SB with treatment of the associated condition will confirm the relationship and establish a more precise diagnosis (ie, secondary SB). Clinicians intending to manage SB should be able to identify these possible clinical interactions, and, if needed, perform an integrative multidimensional approach. Some approaches will benefit from a multidisciplinary approach for achieving therapeutic success.","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"34 3","pages":"236-239"},"PeriodicalIF":2.5,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11607/ofph.2616","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38331815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

The Association Between Self-Reported Awake Oral Behaviors and Orofacial Pain Depends on the Belief of Patients That These Behaviors Are Harmful to the Jaw. 自我报告的清醒口腔行为与口面部疼痛之间的关联取决于患者认为这些行为对颌骨有害的信念。

IF 2.5 3区医学

Journal of Oral & Facial Pain and Headache Pub Date : 2020-06-01 DOI: 10.11607/ofph.2629

Maurits Ka van Selms, Corine M Visscher, Wendy Knibbe, Magdalini Thymi, Frank Lobbezoo

{"title":"The Association Between Self-Reported Awake Oral Behaviors and Orofacial Pain Depends on the Belief of Patients That These Behaviors Are Harmful to the Jaw.","authors":"Maurits Ka van Selms, Corine M Visscher, Wendy Knibbe, Magdalini Thymi, Frank Lobbezoo","doi":"10.11607/ofph.2629","DOIUrl":"https://doi.org/10.11607/ofph.2629","url":null,"abstract":"Aims: To examine if the existence of an association between self-reported awake oral behaviors and orofacial pain depends on the belief of patients that these behaviors are harmful to the jaw and to investigate if an additional variable (ie, somatic symptoms, depression, and/or anxiety) indirectly affects the association between the causal attribution belief and the report of awake oral behaviors.Methods: Prior to the first clinical visit, patients referred to a specialized clinic for complaints of orofacial pain and dysfunction completed a digital questionnaire. Data of 329 patients diagnosed with myalgia according to the Diagnostic Criteria for Temporomandibular Disorders (82.4% women; mean ± SD age = 41.9 ± 14.7 years) were analyzed.Results: Causal attribution belief moderated the association between awake oral behaviors and orofacial pain intensity. In addition, the relationship between causal attribution belief and self-reported oral behaviors was partially mediated by the presence of somatic symptoms (8%), depression (9%), and anxiety (16%).Conclusion: Awake oral behaviors were positively associated with orofacial pain, but only under the condition of a strong belief of the patients in causal attribution of these behaviors to the jaw pain complaint. No such association was present in case of a low causal attribution belief. It appeared that, within this patient cohort, the relationship between causal attribution belief and self-reported oral behaviors was (in part) the result of shared psychologic risk factors.","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"34 3","pages":"273-280"},"PeriodicalIF":2.5,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11607/ofph.2629","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38331813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Treating Temporomandibular Disorders in the 21st Century: Can We Finally Eliminate the "Third Pathway"? 21世纪颞下颌疾病的治疗:我们能最终消除“第三途径”吗?

IF 2.5 3区医学

Journal of Oral & Facial Pain and Headache Pub Date : 2020-06-01 DOI: 10.11607/ofph.2608

Charles S Greene, Daniele Manfredini

{"title":"Treating Temporomandibular Disorders in the 21st Century: Can We Finally Eliminate the \"Third Pathway\"?","authors":"Charles S Greene, Daniele Manfredini","doi":"10.11607/ofph.2608","DOIUrl":"https://doi.org/10.11607/ofph.2608","url":null,"abstract":"Within the orofacial pain discipline, the most common group of afflictions is temporomandibular disorders (TMD). The pathologic and functional disorders included in this condition closely resemble those that are seen in the orthopedic medicine branch of the medical profession, so it would be expected that the same principles of orthopedic diagnosis and treatment are applied. Traditional orthopedic therapy relies on a \"Two Pathway\" approach involving conservative and/or surgical treatments. However, over the course of the 20th century, some members of the dental community have created another way of approaching these disorders- referred to in this paper as the \"Third Pathway\"-based on the assumption that signs and symptoms of TMD are due to a \"bad\" relationship between the mandible and skull, leading to a variety of irreversible occlusal or surgical corrective treatments. Since no other human joint is discussed in these terms within the orthopedic medicine communities, it has become progressively clear that the Third Pathway is a unique and artificial conceptual creation of the dental profession. However, many clinical studies have utilized the medically oriented conservative/surgical Two-Pathway model to diagnose and treat TMD within a biopsychosocial model of pain. These studies have shown that TMD comprise another domain of orthopedic illness that requires a medically oriented approach for good outcomes while avoiding the irreversible aspects of the Third Pathway. This review presents historical and current evidence that the Third Pathway is an example of unorthodox medicine that leads to unnecessary overtreatment and further proposes that it is time to abandon this approach as we move forward in the TMD field.","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"34 3","pages":"206-216"},"PeriodicalIF":2.5,"publicationDate":"2020-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.11607/ofph.2608","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38427134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 19

Entrustable Professional Activities in Postgraduate Orofacial Pain Programs. 研究生口腔面部疼痛项目中可信赖的专业活动。

IF 2.5 3区医学

Journal of Oral & Facial Pain and Headache Pub Date : 2020-06-01 DOI: 10.11607/ofph.2640

James Hawkins, Gary Heir, Jeffrey Okeson, Jeffry Shaefer

引用次数: 3

The Efficacy of Botulinum Toxin in Cluster Headache: A Systematic Review. 肉毒毒素治疗丛集性头痛的疗效:系统评价。

IF 2.5 3区医学

Journal of Oral & Facial Pain and Headache Pub Date : 2020-04-01 DOI: 10.11607/ofph.2444

Brin Freund, Ivan S. Kotchetkov, Aruna S Rao

{"title":"The Efficacy of Botulinum Toxin in Cluster Headache: A Systematic Review.","authors":"Brin Freund, Ivan S. Kotchetkov, Aruna S Rao","doi":"10.11607/ofph.2444","DOIUrl":"https://doi.org/10.11607/ofph.2444","url":null,"abstract":"AIMS\u0000To conduct a systematic review of the literature on the use of botulinum toxin for the treatment of cluster headache.\u0000\u0000\u0000METHODS\u0000A systematic review and data quality analysis were performed using PRISMA and GRADE guidelines, respectively. Inclusion and exclusion criteria were outlined prior to the search and aimed to select prospective studies that examined the use of botulinum toxin for the treatment of cluster headache.\u0000\u0000\u0000RESULTS\u0000Three studies resulted from the search that each included 10 to 17 subjects. All three demonstrated significant improvement in the frequency of headaches that occurred as quickly as 1 week following treatment. There was low-quality evidence that botulinum toxin was effective in reducing headache frequency and severity by at least 50%. Injections into the sphenopalatine ganglion may have a higher incidence of adverse events.\u0000\u0000\u0000CONCLUSION\u0000This review summarizes the only prospectively collected efficacy and safety data regarding the use of botulinum toxin in cluster headache. Off-label use should be considered in certain cases. Further study is warranted to better characterize injection paradigms and patient selection, given the encouraging but limited data available.","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74312989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Sphenopalatine Ganglion Block with Botulinum Neurotoxin for Treating Trigeminal Neuralgia Using CAD/CAM-Derived Injection Guide. 肉毒毒素阻断蝶腭神经节治疗三叉神经痛的CAD/ cam注射指南。

IF 2.5 3区医学

Journal of Oral & Facial Pain and Headache Pub Date : 2020-04-01 DOI: 10.11607/ofph.2510

Kazuya Yoshida

{"title":"Sphenopalatine Ganglion Block with Botulinum Neurotoxin for Treating Trigeminal Neuralgia Using CAD/CAM-Derived Injection Guide.","authors":"Kazuya Yoshida","doi":"10.11607/ofph.2510","DOIUrl":"https://doi.org/10.11607/ofph.2510","url":null,"abstract":"AIMS\u0000To examine the effectiveness and safety of using a CAD/CAM-derived injection guide for botulinum neurotoxin block of the sphenopalatine ganglion for trigeminal neuralgia treatment.\u0000\u0000\u0000METHODS\u0000Ten patients with second-division trigeminal neuralgia who did not respond to submucosal administration of botulinum neurotoxin were enrolled in this study. The target point around the sphenopalatine fossa was determined after fusion of computed tomography data with a scan of a maxillary model using a software program for dental implant surgery. A CAD/CAM-derived injection guide was fabricated. The guide was affixed to the patient's maxilla, and a needle was inserted to an exactly analyzed depth. Subsequently, 50 units of botulinum neurotoxin were injected. Pain intensity evaluated using a visual analog scale and pain frequency were measured.\u0000\u0000\u0000RESULTS\u0000By using the guides, sphenopalatine ganglion block with botulinum toxin was performed 18 times without any complications. The visual analog scale score (8.1 ± 1.0) and pain frequency (19.4 ± 8.8 times/day) decreased (to 1.9 ± 1.4 and 4.9 ± 5.4 times/day, respectively) significantly (P < .001). After 4 weeks, the mean subjective improvement achieved was 77.5% ± 13.8%, and all patients responded to treatment.\u0000\u0000\u0000CONCLUSION\u0000Even without prior experience of sphenopalatine ganglion block, the CAD/CAM-derived guide enabled the accurate and safe administration of botulinum neurotoxin to the sphenopalatine ganglion for the treatment of trigeminal neuralgia.","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"1 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83853073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Features of Neurovascular Orofacial Pain Compared to Painful Posttraumatic Trigeminal Neuropathy. 神经血管性口面部疼痛与创伤后疼痛性三叉神经病变的特征比较。

IF 2.5 3区医学

Journal of Oral & Facial Pain and Headache Pub Date : 2020-04-01 DOI: 10.11607/ofph.2448

Y. Haviv, A. Zini, N. Keshet, G. Almoznino, R. Benoliel, Y. Sharav

{"title":"Features of Neurovascular Orofacial Pain Compared to Painful Posttraumatic Trigeminal Neuropathy.","authors":"Y. Haviv, A. Zini, N. Keshet, G. Almoznino, R. Benoliel, Y. Sharav","doi":"10.11607/ofph.2448","DOIUrl":"https://doi.org/10.11607/ofph.2448","url":null,"abstract":"AIMS\u0000To test and re-examine the diagnostic criteria for neurovascular orofacial pain (NVOP) compared to posttraumatic trigeminal neuropathy (PTTN).\u0000\u0000\u0000METHODS\u0000Pain and patient characteristics were compared in patients with NVOP, PTTN, and NVOP initiated by trauma (PT-NVOP). NVOP criteria were based on prior studies, and PTTN was defined according to the International Classification of Headache Disorders, version 3 beta.\u0000\u0000\u0000RESULTS\u0000Of the 170 patients in the cohort, 90 had PTTN, 51 had NVOP, and 29 had PT-NVOP. None of the tested parameters in the NVOP and PT-NVOP patients were significantly different, and therefore these patients were combined into one group (T-NVOP). T-NVOP differed significantly from PTTN (P < .001) in periodic pain patterns, presence of autonomic and systemic signs, throbbing pain quality, and frequency of bilaterality. Pain quality in PTTN was more burning/stabbing than in NVOP (P = .003). Pain severity, waking from sleep, muscle sensitivity to palpation, and demographics were comparable.\u0000\u0000\u0000CONCLUSION\u0000NVOP differs from PTTN in parameters essential to diagnosis: periodicity of pain, presence of autonomic and systemic accompanying signs, throbbing pain quality, and bilateral presentation. NVOP is amenable to abortive and prophylactic antimigraine therapies, distinguishing NVOP from PTTN in clinical features, treatment, and prognosis.","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"15 1","pages":""},"PeriodicalIF":2.5,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84332265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Effect of Platelet-Rich Plasma Injections on Pain Reduction in Patients with Temporomandibular Joint Osteoarthrosis: A Meta-Analysis of Randomized Controlled Trials. 富血小板血浆注射对减轻颞下颌关节骨关节病患者疼痛的效果：随机对照试验的元分析》。

IF 2.5 3区医学

Journal of Oral & Facial Pain and Headache Pub Date : 2020-02-01 DOI: 10.11607/ofph.2470

Fulong Li, Chuanbin Wu, Haijiang Sun, Qing Zhou

{"title":"Effect of Platelet-Rich Plasma Injections on Pain Reduction in Patients with Temporomandibular Joint Osteoarthrosis: A Meta-Analysis of Randomized Controlled Trials.","authors":"Fulong Li, Chuanbin Wu, Haijiang Sun, Qing Zhou","doi":"10.11607/ofph.2470","DOIUrl":"10.11607/ofph.2470","url":null,"abstract":"Aims: To study the effect of platelet-rich plasma (PRP) injections on pain reduction in patients with temporomandibular joint osteoarthritis (TMJ OA).Methods: The authors performed a comprehensive search of the MEDLINE, PubMed, and Web of Science databases to retrieve RCTs published up to July 2018. Pain outcomes (visual analog scale scores) were extracted to assess the effect of PRP injections on TMJ OA. All data analyses were conducted using RevMan 5.3.Results: Six studies were included. According to the results of these trials, intra-articular injections of PRP were more effective than placebo for pain reduction (6 months postinjection: mean difference [MD] -2.82, 95% CI -3.39 to -2.25, P < .00001; 12 months postinjection: MD -3.29; 95% CI -4.07 to -2.52, P < .00001). Additionally, the comparison between PRP and hyaluronic acid injections showed a statistically significant difference in pain reduction in support of PRP (MD -0.81; 95% CI -1.22 to -0.40; P = .0001) at 12 months postinjection. All trials revealed a moderate risk of bias.Conclusion: Based on current evidence, PRP injections may reduce pain more effectively than placebo injections in TMJ OA at 6 months (level of evidence: moderate) and 12 months (level of evidence: moderate) postinjection. This significant difference in pain reduction could also be seen when PRP was compared to hyaluronic acid at 12 months postinjection (level of evidence: low). It can be cautiously interpreted that PRP has a beneficial effect on the relief of TMJ OA pain. Large-scale, low-bias RCTs are needed to test whether PRP injection should be a routine treatment for patients with TMJ OA.","PeriodicalId":48800,"journal":{"name":"Journal of Oral & Facial Pain and Headache","volume":"34 2","pages":"149-156"},"PeriodicalIF":2.5,"publicationDate":"2020-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37807196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0