Journal of Global Health最新文献

{"title":"A successful response to the second wave of COVID-19 in the slums of Delhi.","authors":"John Peteet, Kiran Martin, Jean Peteet","doi":"10.7189/jogh.15.03032","DOIUrl":"10.7189/jogh.15.03032","url":null,"abstract":"<p><p>The second wave of the COVID-19 pandemic presented unprecedented challenges to India's slum communities. Although more COVID-related deaths occurred in slum neighbourhoods, the 91 slum communities served by the non-profit Asha Society India experienced only one death case during this period. Key factors contributing to this outcome included the mobilisation of educational, quarantine, and preventive measures, as well as an emergency protocol that was used for early proactive identification and treatment of patients presenting with fever and cough before experiencing shortness of breath indicative of a developing cytokine storm and its life-threatening complications. This retrospective description is limited by the incompleteness of data collected during the chaos of the pandemic.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"03032"},"PeriodicalIF":4.3,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12333568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Countdown to 2030: overview of current and planned health financing reforms for universal health coverage in the WHO African Region.","authors":"Doris Osei Afriyie, Diane Karenzi Muhongerwa, Juliet Nabyonga-Orem, Ogochukwu Chukwujekwu","doi":"10.7189/jogh.15.04233","DOIUrl":"10.7189/jogh.15.04233","url":null,"abstract":"<p><strong>Background: </strong>Countries in the World Health Organization (WHO) African region are lagging behind in the global push toward universal health coverage (UHC), a core component of the 2030 Agenda for Sustainable Development. As the target year steadily approaches, it is crucial to assess countries' current and planned health financing reforms to understand their path towards UHC. We examine both current and planned health financing reforms in the WHO African region and assess their implications for UHC.</p><p><strong>Methods: </strong>We sent a survey to all 47 Member States of the WHO African Region in August 2024 about their current and planned health financing reforms in the three health financing functions of revenue raising, pooling, and purchasing, as well as public finance management. We used responses from 43 countries, of which 18 countries had a current endorsed national health financing strategy to assess the implications of their reforms based on current literature on using health financing to progress towards UHC goals.</p><p><strong>Results: </strong>Of the 43 countries in the WHO African Region that responded to our survey, 33 (77%) have current or planned health financing reforms across the various health financing functions. A major focus of these reforms is on establishing contributory health insurance schemes, despite their limited potential to address the region's challenges. Additionally, countries are prioritising expanding performance-based financing and provider payment mechanisms. These purchasing strategies could improve service coverage and quality of care if implemented within robust public finance management structures.</p><p><strong>Conclusions: </strong>Countries in the WHO African Region are adopting and planning various health financing reforms to achieve UHC. To ensure success, they will require support in effectively implementing evidence-based reforms in the areas of purchasing and reducing fragmentation from various coverage schemes.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04233"},"PeriodicalIF":4.3,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12333570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The burden of common mental disorders and their association with diabetes in rural Bangladesh: findings from a population-based cross-sectional study.","authors":"Malini Pires, Carina King, Sanjit Shaha, Abdul Kuddus, Naveed Ahmed, Joanna Morrison, Andrew Copas, Sarker Ashraf Uddin Ahmed, Tasmin Nahar, Hassan Haghparast-Bidgoli, Kishwar Azad, Edward Fottrell","doi":"10.7189/jogh.15.04220","DOIUrl":"10.7189/jogh.15.04220","url":null,"abstract":"<p><strong>Background: </strong>Type 2 diabetes mellitus (T2DM) and common mental disorders (CMDs), including depression and anxiety, are significant public health challenges, particularly in low- and middle-income countries (LMICs). However, evidence on the distribution and associations between T2DM and CMDs in rural LMIC populations remains limited. We aimed to examine this relationship in a sample of adults from rural Bangladesh.</p><p><strong>Methods: </strong>In this cross-sectional study, we analysed baseline data from a cluster-randomised controlled trial conducted in rural Faridpur, Bangladesh in 2021. A total of 1392 randomly sampled adults aged ≥30 years participated in the original trial. Here, we identified T2DM through fasting glucose levels and post-glucose load results, or self-reported healthcare diagnosis. We assessed depression and anxiety using the Bangla versions of the Patient Health Questionnaire and Generalized Anxiety Disorder 7 scales. Among others, we also collected data on sociodemographic factors. We assessed the prevalence of different CMDs and T2DM, and estimated the association between the two through multivariate logistic regression adjusted for sociodemographic variables.</p><p><strong>Results: </strong>We found a prevalence of 6.0% for depression, 4.0% for anxiety, and 2.2% for the comorbid depression and anxiety. Compared to those without T2DM, participants with T2DM had higher odds of having depression (adjusted odds ratio (aOR) = 1.93; 95% confidence interval (CI) = 1.37-2.73) and comorbid depression and anxiety (aOR = 1.99; 95% CI = 1.13-3.50). No significant association was found between T2DM and anxiety (aOR = 1.38; 95%CI = 0.87-2.19). Age, marital status, and employment also influenced CMD risk.</p><p><strong>Conclusions: </strong>There is a significant association between T2DM, depression, and comorbid depression and anxiety in rural Bangladesh, with gender potentially playing a modifying role. Integrated, gender-sensitive care models addressing both mental health and diabetes are essential in rural healthcare settings.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04220"},"PeriodicalIF":4.3,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12333571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Respiratory viral infections: when and where? A scoping review of spatiotemporal methods.","authors":"Jingyi Liang, Daniel Horvath, Saturnino Luz, You Li, Harish Nair","doi":"10.7189/jogh.15.04213","DOIUrl":"10.7189/jogh.15.04213","url":null,"abstract":"<p><strong>Background: </strong>Respiratory viral infections pose a substantial disease burden worldwide. Spatiotemporal techniques help identify transmission patterns of these infections, thereby supporting timely control and prevention efforts. We aimed to synthesise the current state of evidence on quantitative methodologies for investigating the spatiotemporal characteristics of respiratory viral infections.</p><p><strong>Methods: </strong>We conducted a scoping review using the PRISMA-ScR guidelines. We searched three biomedical bibliographic databases, EMBASE, MEDLINE, and Web of Science, identifying studies that analysed spatiotemporal transmission of viral respiratory infectious diseases (published before 1 March 2023).</p><p><strong>Results: </strong>We identified 8466 articles from database searches, of which 152 met our inclusion criteria and were qualitatively synthesised. Most included articles (n = 140) were published during the COVID-19 pandemic, with 131 articles specifically analysing COVID-19. Exploratory research (n = 77) investigated the spatiotemporal transmission characteristics of respiratory infectious diseases, focussing on transmission patterns (n = 16), and influencing factors (n = 61). Forecasting research (n = 75) aimed to predict the disease trends using either univariate (n = 57) or multivariate models (n = 18), predominantly using machine learning methods (n = 41). The application of advanced deep learning models (n = 20) in disease forecasting analysis was often constrained by the quality of the available disease data.</p><p><strong>Conclusions: </strong>There is a growing body of research on spatiotemporal analyses of respiratory viral infections, particularly during the COVID-19 pandemic. The acquisition of high-quality data remains important for effectively leveraging sophisticated models in disease forecasting research. Concurrently, although advanced modelling techniques are widely applied, future studies should consider capturing the complex spatiotemporal interactions in disease trajectory modelling.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04213"},"PeriodicalIF":4.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the burden of respiratory tract infections among mortality cases in Karachi, Pakistan: a post-pandemic surveillance analysis.","authors":"Furqan Kabir, Raheel Allana, Inci Yildirim, Aneeta Hotwani, Sameer M Belgaumi, Fatima Aziz, Fauzia Aman Malik, Saima Jamal, Obianuju Aguolu, Nazia Ahsan, Zahra Hasan, Shabina Ariff, Saad B Omer, Abdul Momin Kazi","doi":"10.7189/jogh.15.04198","DOIUrl":"10.7189/jogh.15.04198","url":null,"abstract":"<p><strong>Background: </strong>Respiratory tract infections (RTIs) significantly impact global health, but particularly affect low- and middle-income countries. They contribute to morbidity and mortality, especially among vulnerable populations. We evaluated the burden of RTIs in mortality cases in an urban slum of Karachi, Pakistan, during the post-COVID-19 pandemic period.</p><p><strong>Methods: </strong>We conducted a prospective observational study from September 2022 to October 2023 in Ali Akbar Shah, Karachi. We collected 350 nasal swabs from deceased individuals and tested them for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other respiratory pathogens using reverse transcription polymerase chain reaction (RT-PCR) and the TaqMan Array Card (TAC) assay. Additionally, we performed verbal autopsies to determine the cause of death.</p><p><strong>Results: </strong>Most deaths occurred at home (n/N = 234/350, 66.8%). Hospital-based deaths were more common among children under five years of age (n/N = 81/132, 61.3%), while individuals over five were more likely to die at home (n/N = 180/211, 85.3%). In the post-pandemic period, 6% (n/N = 21/350) of deceased individuals tested positive for COVID-19. The TAC assay analysis found Klebsiella pneumoniae (n/N = 150/350, 42.8%), Staphylococcus aureus (n/N = 141/350, 40.3%), and Streptococcus pneumoniae (n/N = 106/350, 30.3%) to be the most common pathogens. Co-infections were common, with 90.4% of COVID-19-positive cases also harbouring other respiratory pathogens.</p><p><strong>Conclusions: </strong>We observed a high burden of RTIs in Karachi, with Klebsiella pneumoniae playing a major role in overall mortality across all age groups. Co-infections with multiple respiratory pathogens were common, underscoring the need for better diagnostic and treatment strategies. Improved surveillance and potential vaccine development for Klebsiella pneumoniae and other notable pathogens could reduce mortality in similar settings. However, limitations such as post-mortem colonisation, contamination, and the absence of histopathologic confirmation necessitate cautious interpretation of pathogen-related mortality.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04198"},"PeriodicalIF":4.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319414/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of an innovative, competency-based, multi-speciality training programme in global health for graduate medical education.","authors":"Elizabeth S Rose, Rondi M Kauffmann, Marie H Martin, J Matthew Kynes, Lipika Narisetti, Ryan H Belcher, Christopher M Bonfield, Kristen B Dettorre, Michael C Dewan, Joseline Haizel-Cobbina, Merranda D Holmes, Tolulope O Kehinde, Jonathan A Niconchuk, Kush Chaudhari, Annesa Dey, Jada S Sims, Teresa Y Xu, Lindsey E Zamora","doi":"10.7189/jogh.15.03029","DOIUrl":"10.7189/jogh.15.03029","url":null,"abstract":"<p><p>Physicians increasingly care for ethnically diverse populations. Demand for global health training in graduate medical education (GME) is increasing, but there is variability across specialities. We developed a multi-speciality GME course for trainees seeking to integrate global health into their careers. The Consortium of Universities in Global Health's Toolkit was the foundation for creating this course. The course includes eleven modules taught by faculty across specialities. Trainees completed pre- and post-course online surveys to measure their knowledge, skills, and attitudes on these global health competencies and to gather course feedback. We compared pre- and post-course data to determine change in global health competencies and course perceptions. In the first two years, 62 residents participated. Overall, trainees' knowledge of international health concepts increased by 51%. The course was well received; 95% would recommend the course to a colleague. There was no fee to participate. Faculty donated their effort to developing and teaching the course. Faculty worked in pairs to maintain feasibility of implementation and were responsible for one module. Analyses showed the course had high levels of effectiveness in increasing learners' knowledge, acceptability by learners, and feasibility of implementation. This programme collaborates across specialities and is a model for other GME programmes.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"03029"},"PeriodicalIF":4.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The contribution of minimally invasive tissue sampling compared to antemortem-derived cause of death determination among inpatient child deaths: the minimally invasive tissue sampling in Malawi study.","authors":"Wieger P Voskuijl, Dennis Chasweka, Sarah Lawrence, Daniella Brals, Steve Kamiza, Robert Bandsma, James A Berkley, Emmie Mbale, Charalampos Attipa, Chisomo Eneya, Cornelius Huwa, Stanley Khoswe, Christopher Moxon, Isabel Potani, Jessica L Waller, Maureen H Diaz, Judd Walson, Jaume Ordi, Donna M Denno","doi":"10.7189/jogh.15.04210","DOIUrl":"10.7189/jogh.15.04210","url":null,"abstract":"<p><strong>Background: </strong>Improved causes of death (CoD) understanding in low- and middle-income countries is needed to reduce child mortality. Compared to full autopsy, minimally invasive tissue sampling (MITS), using transcutaneous needle sampling, is a feasible, socially acceptable, and validated method. We aimed to quantify the additional contribution of MITS to CoD attribution based on clinical records and inpatient research data with intensive patient characterisation.</p><p><strong>Methods: </strong>We enrolled children aged seven days to 59 months who died while on admission for acute illness and/or severe malnutrition to Queen Elizabeth Central Hospital in Blantyre, Malawi. Standard MITS procedures included histologic, immunohistochemical, and microbiologic testing. Phase 1 CoD determination was based on medical records alone, Phase 2 also included research data, and Phase 3 included all data, including from MITS.</p><p><strong>Results: </strong>We enrolled 29 children. Based on clinical notes alone (Phase 1), we identified 60 causal and 39 contributing conditions. Of the 45 (45%) infectious conditions, pathogens were identified in 15 (33%). Only one patient's (3%) CoD was unchanged compared to including all data (Phase 3). Further, we identified 69 new (n = 43) or adjusted (n = 26) diagnoses among 28 cases (97%); the majority were undernutrition-related (n = 22, 32%) or infectious (n = 41, 59%) conditions. Overall, the majority of final Phase 3 conditions were also undernutrition-related (n = 46, 32%) or infectious (n = 61, 43%) and a pathogen was identified in 54 (89%) of the infectious conditions. Klebsiella pneumoniae was the most prevalent aetiology in both pneumonia and sepsis.</p><p><strong>Conclusions: </strong>The addition of MITS to clinical and inpatient research data led to almost all (97%) of cases receiving new and/or refined diagnoses, including microbe identification in infectious conditions. Pathogens not specifically addressed by current clinical guidelines, such as Klebisiella pneumoniae, were commonly identified. Our findings support the utility of MITS to understand CoD even after thorough clinical characterisation of children during hospitalisation.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04210"},"PeriodicalIF":4.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319396/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management and outcomes of chest-indrawing pneumonia among children aged 2-59 months in a programme setting in Ethiopia: a prospective observational study.","authors":"Zemene Tigabu, Alemayehu Teklu Toni, Tadesse Guadu, Tesfahun Melese Yilma, Tadesse Awoke, Garedew Tadege Engdaw, Ashenafi Tazebew, Shamim Ahmad Qazi, Yasir Bin Nisar","doi":"10.7189/jogh.15.04217","DOIUrl":"10.7189/jogh.15.04217","url":null,"abstract":"<p><strong>Background: </strong>Pneumonia is a leading cause of morbidity and mortality in children under five years of age. In 2012, the World Health Organization revised its guidelines for managing childhood pneumonia and recommended oral amoxicillin for the outpatient treatment of chest indrawing pneumonia in children aged 2-59 months. While the Ethiopian government subsequently adopted these revised pneumonia guidelines, the level of their implementation and of the related treatment outcomes remains less known. We aimed to determine the outcomes of this approach at primary healthcare facilities in Ethiopia.</p><p><strong>Methods: </strong>We conducted a prospective, observational cohort study at five health centres in Northern Ethiopia from November 2022 to November 2023. Trained health workers screened all children aged 2-59 months who had cough or difficult breathing and managed them according to the integrated management of childhood illness chart booklet. Children with chest indrawing pneumonia who lived in the study catchment area and whose parents or guardians consented were enrolled. An independent data collector conducted a follow-up visit on day 15 to collect information on their survival status and the treatment received after enrolment. The primary outcome was case fatality risk (CFR), calculated as the proportion of children who died by day 15 after enrolment among all enrolled children.</p><p><strong>Results: </strong>We screened 3492 children aged 2-59 months, enrolling 345 with chest indrawing pneumonia. All were prescribed oral amoxicillin. The majority (n = 340, 98.6%), received a five-day prescription, while the remaining five were prescribed a seven-day course. We assessed 333 children on day 15 for study outcomes. Twelve (3.5%) were lost to follow-up. Two children died, resulting in a CFR of 0.6 (95% confidence interval = 0.35, 0.85). Most children (n = 315, 94.6%), adhered to the five-day course of amoxicillin, while 18 (5.4%) did not complete the entire course. Thirteen (3.9%) children were taken to a hospital between days two and 15, six received outpatient treatment, and seven were hospitalised. All 13 were alive and well on day 15.</p><p><strong>Conclusions: </strong>In a programme setting, children aged 2-59 months with chest indrawing pneumonia managed at the primary healthcare facilities on an outpatient basis with oral amoxicillin had low CFR, low hospitalisation rates, and high adherence to treatment.</p><p><strong>Registration: </strong>ISRCTN: 12687253.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04217"},"PeriodicalIF":4.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systems-change approach to addressing the mortality surveillance gap in Pakistan.","authors":"Mohummad Hassan Raza Raja, Zahra Hoodbhoy, Sana Sheikh, Muhammad Imran Nisar, Sajid Bashir Soofi, Sameen Siddiqi, Zafar Mirza, Faiza Bashir, Mirza Tayyab Mehmood, Zainab Samad","doi":"10.7189/jogh.15.03027","DOIUrl":"10.7189/jogh.15.03027","url":null,"abstract":"<p><p>With a lack of cause of death estimation and an inadequate and fragmented Civil Registration and Vital Statistics system, Pakistan faces a significant gap in data on mortality. This poses significant challenges for health policy planning and monitoring. In this viewpoint, we draw on systems-change frameworks to examine and provide recommendations to improve mortality surveillance in Pakistan. We use the multiple cause diagram framework to understand the challenges and barriers to instituting a robust mortality surveillance system in Pakistan. We also examine current and future scenarios and what it will take to get to best future scenarios using the Theory of Change model. Through the multiple cause diagram mapping, we show that the poorly functioning mortality surveillance system in Pakistan is underlain by multiple complex and interrelated multisectoral challenges. However, a cost-effective, agile, and data-lean system of mortality surveillance can exist through strengthening already existing systems. This could be accompanied with context- and resource-sensitive use of different types of surveillance methods such as verbal autopsy tools implemented in the community and integrated into sample registration systems, as well as hospital-based surveillance in urban areas with government coordination. This can be achieved with cross-sectoral, cross-agency collaboration, capacity strengthening, and local stakeholder involvement.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"03027"},"PeriodicalIF":4.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beverage consumption on bone and joint disorders: an umbrella review.","authors":"Han Tan, Peiyuan Tang, Hua Chai, Wenbo Ma, Yangbin Cao, Bin Lin, Ying Zhu, Wenfeng Xiao, Ting Wen, Bangbao Lu, Yusheng Li","doi":"10.7189/jogh.15.04222","DOIUrl":"10.7189/jogh.15.04222","url":null,"abstract":"<p><strong>Background: </strong>Bone and joint disorders significantly contribute to disability worldwide. While meta-analyses have explored the relationship of these diseases and beverage consumption, the results remain inconsistent. In this umbrella review, we synthesised existing evidence to clarify these associations.</p><p><strong>Methods: </strong>We conducted a systematic search in PubMed, Embase, Cochrane, and Web of Science up to January 2025. Two independent reviewers screened studies and extracted data based on predefined criteria. We included meta-analyses and systematic review studies. We used the Graphical Representation of Overlap for Overviews tool to manage overlapping studies and assessed methodological quality and evidence levels using AMSTAR 2 tool and the GRADE system. We narratively synthesised the findings and summarised them in tables.</p><p><strong>Results: </strong>We included 20 meta-analyses. Tea consumption was associated with a reduced risk of osteoporosis (odds ratio (OR) = 0.71; 95% confidence interval (CI) = 0.60, 0.83; P < 0.0001; I² = 13%), while coffee showed mixed results. Alcohol intake increased osteoporosis risk (OR = 2.95; 95% CI = 1.78, 4.9; P < 0.0001; I² = 0%). Sugar-sweetened beverages raised gout risk (relative risk (RR) = 1.35; 95% CI = 1.18, 1.55, P < 0.05; I² = 40.1%) and serum uric acid levels, while coffee lowered gout risk (RR = 0.43; 95% CI = 0.31, 0.59; P < 0.001; I² = 0%). Coffee was associated with a higher risk of rheumatoid arthritis (RR = 1.3; 95% CI = 1.04, 1.62; P < 0.05; I² = 0%), while tea showed no significant effect.</p><p><strong>Conclusions: </strong>Tea may benefit bone and joint health, while alcohol and sugar-sweetened beverages are associated with a higher incidence of bone and joint conditions, such as osteoporosis, rheumatoid arthritis, and gout. These findings emphasise the importance of dietary choices in preventing bone and joint disorders.</p><p><strong>Registration: </strong>PROSPERO (CRD42024551504).</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04222"},"PeriodicalIF":4.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12319397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}