Journal of Global Health最新文献

筛选
英文 中文
Global epidemiology, viral evolution, and public health responses: a systematic review on Mpox (1958-2024). 全球流行病学、病毒演变和公共卫生反应:关于m痘的系统综述(1958-2024)。
IF 4.5 3区 医学
Journal of Global Health Pub Date : 2025-03-07 DOI: 10.7189/jogh.15.04061
Vivekanand Jadhav, Arundhuti Paul, Vivek Trivedi, Ritu Bhatnagar, Rahul Bhalsinge, Savita V Jadhav
{"title":"Global epidemiology, viral evolution, and public health responses: a systematic review on Mpox (1958-2024).","authors":"Vivekanand Jadhav, Arundhuti Paul, Vivek Trivedi, Ritu Bhatnagar, Rahul Bhalsinge, Savita V Jadhav","doi":"10.7189/jogh.15.04061","DOIUrl":"10.7189/jogh.15.04061","url":null,"abstract":"<p><strong>Background: </strong>Monkeypox (Mpox), a zoonotic viral disease caused by the Mpox virus (MPOXV), was first identified in 1958 and remained largely confined to Central and West Africa for decades. While it usually exhibited limited international transmission, recent outbreaks, including in the USA in 2003 and globally in 2024, highlight significant epidemiological shifts. We aimed to systematically evaluate the evolution of Mpox from 1958 to 2024, focussing on its epidemiology, viral evolution, and public health responses.</p><p><strong>Methods: </strong>We conducted a systematic review using data from global health reports, surveillance databases, and published literature. The analysis covered key outbreaks, transmission patterns, geographic distribution, public health responses, and the roles of viral mutations and vaccination in disease management.</p><p><strong>Results: </strong>The 2022 Mpox outbreak, declared a Public Health Emergency of International Concern by the World Health Organization (WHO), was characterised by an unprecedented international spread of the virus. By July 2024, a total of 102 997 confirmed cases and 223 deaths were reported across 121 countries. Two distinct viral clades were identified: Central African (clade I) and West African (clade II), with the latter being the primary agent of global transmission. Research on Mpox has highlighted the protective effects of smallpox vaccination and emerging risk factors such as human-animal interactions and international travel.</p><p><strong>Conclusions: </strong>Mpox has evolved from a regionally contained zoonotic disease to a global public health challenge. Enhanced surveillance, international collaboration, and targeted interventions in non-endemic regions are critical for mitigating future outbreaks and managing ongoing epidemiological changes.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04061"},"PeriodicalIF":4.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11893143/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Universal health coverage in Cambodia: current status and future prospects. 柬埔寨全民健康覆盖:现状和未来前景。
IF 4.5 3区 医学
Journal of Global Health Pub Date : 2025-03-07 DOI: 10.7189/jogh.15.03016
Virak Sorn
{"title":"Universal health coverage in Cambodia: current status and future prospects.","authors":"Virak Sorn","doi":"10.7189/jogh.15.03016","DOIUrl":"10.7189/jogh.15.03016","url":null,"abstract":"<p><p>Despite improvements in health indices over the past decades, Cambodia faces significant challenges in achieving universal health coverage (UHC). With an effective UHC score of 58 in 2021 - lower than regional neighbours - the country struggles with disparities in health care access, urban-rural inequalities, and rising non-communicable diseases. The health care system continues to be heavily privatised, with out-of-pocket charges accounting for 55% of overall health expenditures in 2021. Although they have increased financial protection, government programs like the National Social Security Fund and Health Equity Funds are still insufficient. Strengthening public health care, decentralising governance, adopting digital health solutions, and establishing a Public Health Commission are crucial steps toward an equitable and effective UHC by 2035.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"03016"},"PeriodicalIF":4.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Care cascades of diabetes and hypertension among late adolescents in India. 印度晚期青少年糖尿病和高血压的护理级联。
IF 4.5 3区 医学
Journal of Global Health Pub Date : 2025-03-07 DOI: 10.7189/jogh.15.04101
Bijaya Kumar Malik, Amit Kumar Goyal, Suraj Maiti, Sanjay K Mohanty
{"title":"Care cascades of diabetes and hypertension among late adolescents in India.","authors":"Bijaya Kumar Malik, Amit Kumar Goyal, Suraj Maiti, Sanjay K Mohanty","doi":"10.7189/jogh.15.04101","DOIUrl":"10.7189/jogh.15.04101","url":null,"abstract":"<p><strong>Background: </strong>Diabetes and hypertension are the most prevalent morbidities in India and are quickly becoming common among the younger age groups. Adolescents aged 10-19 years, accounting for one-fifth of the country's population, are at an increasing risk of developing these conditions. We aim to examine the prevalence, awareness, treatment, and control (ATC) of diabetes and hypertension among late adolescents (15-19 years) in India.</p><p><strong>Methods: </strong>We used microdata of 204 346 late adolescents from India's fifth round of the National Family and Health Survey, 2019-21. We defined hypertensive adolescents as those diagnosed with hypertension or those with a systolic blood pressure (BP) measurement of ≥130 mm Hg, diastolic BP measurements of levels ≥80 mm Hg, or those who used medication to lower BP at the time of the survey. Diabetic adolescents were those diagnosed as such by health professionals, those with glucose levels above 140 mg/dL, or those taking any medication to control high blood glucose levels at the time of the survey. We estimated the age-sex-adjusted prevalence of both conditions and their ATC rates, referred to as cascade care. We used the Erreygers' Concentration Index to examine the socioeconomic inequality in cascade care. We used multivariable logistic regression to estimate the average marginal effects while controlling for sociodemographic characteristics.</p><p><strong>Results: </strong>Of 204 346 late adolescents, 27.8% (95% confidence interval (CI) = 27.6, 28.2) had either of the two conditions, with 3.5% (95% CI = 3.4, 3.6) being diabetic and 24.3% (95% CI = 24.0, 24.6) having hypertension. The ATC rate of diabetes was 13.5% (95% CI = 12.4, 14.7), 13.1% (95% CI = 11.9, 14.2), and 12.1% (95% CI = 11.0, 13.3), respectively. For hypertension, the ATC rate was extremely low at 6.2% (95% CI = 5.8, 6.5), 3.5% (95% CI = 3.3, 3.7), and 3.3% (95% CI = 3.1, 3.5), respectively. There was a pro-rich socioeconomic inequality in the prevalence of hypertension and a pro-poor inequality in the prevalence of diabetes among late adolescents. We observed significant variations in both conditions across the regions of India.</p><p><strong>Conclusions: </strong>The high prevalence and low care cascade levels of diabetes and hypertension among late adolescents in India are concerning. A multipronged strategy that includes screening, diagnosis, and timely interventions at school and home can reduce the burden of hypertension and diabetes among the prospective workforce in India. Sensitising adolescents through school curricula under the New Education Policy (2020) is recommended to reduce the burden of these conditions. We also recommend that longitudinal and intervention studies focussed on this age group be undertaken in the future to help reduce the disease burden.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04101"},"PeriodicalIF":4.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Benefits and challenges of cervical cancer screening since the implementation of the 'two cancer' screening programme in China: findings from Shangyu, Zhejiang in 2019-23. 自中国实施“两癌”筛查计划以来,宫颈癌筛查的益处和挑战:2019-23年浙江上虞市的调查结果
IF 4.5 3区 医学
Journal of Global Health Pub Date : 2025-03-07 DOI: 10.7189/jogh.15.04064
Yinfang Wu, Jianqiao Luo, Danping Ye, Shujun Gao
{"title":"Benefits and challenges of cervical cancer screening since the implementation of the 'two cancer' screening programme in China: findings from Shangyu, Zhejiang in 2019-23.","authors":"Yinfang Wu, Jianqiao Luo, Danping Ye, Shujun Gao","doi":"10.7189/jogh.15.04064","DOIUrl":"10.7189/jogh.15.04064","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Cervical cancer is the fourth most common cancer in women worldwide. The World Health Organization has long targeted its elimination and stressed the need for enhanced screening coverage and improved treatment rates. The Chinese government initiated the 'two cancer' screening programme for cervical and breast cancer in 2009 for women aged 35-64 years, which Shangyu fully implemented in 2017. We evaluated the programme's progress in Shangyu using data from 2019-23, aiming to suggest feasible improvements and provide general recommendations for regions facing similar challenges.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We used data collected and shared by the Shaoxing Shangyu Maternal and Child Health Hospital from 2019 to 2023. The study sample included 59 201 unemployed women aged 35-64 residing in Shangyu, Shaoxing with no previous cervical cancer histories. Following international guidance, we sent their cervical samples for HPV genotyping and liquid cytology testing and asked them to receive colposcopy as needed for eventual diagnosis, which was subsequently categorised into normal, low-grade cervical intraepithelial neoplasia (CIN 1), high-grade cervical intraepithelial neoplasia (CIN 2-3), squamous cell carcinoma (SCC), adenocarcinoma in situ (AIS), and adenocarcinoma (AA). We used logistic regressions to investigate potential associations between participants' demographic characteristics, risks of HPV positivity, and eventual diagnosis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The prevalence of HPV was 11.65% between 2019 and 2023. The three most common subtypes were HPV-52, HPV-16, and HPV-59. Among those who tested positive and received colposcopy, 97.05% had a normal diagnosis, 1.68% had CIN 1, 0.64% had CIN 2-3, 5.74‱ had SCC, 0.68‱ had AIS, and 0.51‱ had AA. Participants aged 50-54 years (adjusted odds ratio (aOR) = 1.19; 95% confidence interval (CI) = 1.02-1.38), 60-64 years (aOR = 1.33; 95% CI = 1.13-1.57), and those who took birth control pills alone (aOR = 2.35; 95% CI = 1.24-4.46) were associated with an increased likelihood of being tested HPV-positive. Older ages, specifically 55-59 years (aOR = 0.53; 95% CI = 0.29-0.96) and 60-64 years (aOR = 0.46; 95% CI = 0.25-0.85), were associated with a decreased likelihood of developing CIN 2-3. Contraceptive use of intrauterine devices alone was associated with an increased likelihood of developing CIN 2-3 (aOR = 1.41; 95% CI = 1.00-1.99). Being in menopause was associated with a decreased likelihood of developing SCC (aOR = 0.2; 95% CI = 0.06-0.65).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;As the pilot city of the 'two cancer' screening programme, Shangyu saw a gradual yearly increase in cervical cancer screening coverage. However, lack of awareness, reluctance to receive screening and later colposcopy, and underutilisation of screening alternatives undermined further progress. Future medical services and policies should prioritise health education and target neglected groups i","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04064"},"PeriodicalIF":4.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11884646/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of intensive health education on influenza vaccination and acute exacerbations in outpatients with chronic obstructive pulmonary disease: a real-world study. 强化健康教育对流感疫苗接种和慢性阻塞性肺疾病门诊患者急性加重的影响:一项真实世界的研究
IF 4.5 3区 医学
Journal of Global Health Pub Date : 2025-03-07 DOI: 10.7189/jogh.15.04047
Cong Liu, Qing Song, Ling Lin, Tao Li, Ping Zhang, Yuqin Zeng, Yating Peng, Yan Chen, Shan Cai, Ping Chen
{"title":"Impact of intensive health education on influenza vaccination and acute exacerbations in outpatients with chronic obstructive pulmonary disease: a real-world study.","authors":"Cong Liu, Qing Song, Ling Lin, Tao Li, Ping Zhang, Yuqin Zeng, Yating Peng, Yan Chen, Shan Cai, Ping Chen","doi":"10.7189/jogh.15.04047","DOIUrl":"10.7189/jogh.15.04047","url":null,"abstract":"<p><strong>Background: </strong>The influenza vaccination rate of chronic obstructive pulmonary disease (COPD) patients in China was very low. In this study, we aimed to evaluate the effect of clinician-led intensive health education on influenza vaccination in outpatients with COPD and the effect of influenza vaccination on the risk of acute exacerbations in the real world.</p><p><strong>Methods: </strong>Participants were from the Real World Research of Diagnosis and Treatment of COPD study, a real-world prospective cohort study. COPD patients were included from December 2016 to April 2023 and followed up for one year. In January 2022, clinicians began strengthening health education for outpatients with COPD. We identified patients visiting the clinic from January 2022 to April 2023 as the intensive health education group and those visiting from December 2016 to December 2021 as the control group. We analysed factors associated with influenza vaccination and the effect of influenza vaccine on acute exacerbations by multivariate analysis.</p><p><strong>Results: </strong>7834 patients were included. Compared with the control group, the intensive health education group had a higher rate of influenza vaccination (1.6% vs. 12.2%, P < 0.01). Smoking cessation, high school education or above, influenza vaccination in the past year and intensive health education were independently associated with influenza vaccination. Influenza vaccination reduced the incidence of future acute exacerbations (adjusted odds ratio (aOR) = 0.48; 95% confidence interval (CI) = 0.33-0.68, P < 0.01), frequent acute exacerbations (aOR = 0.47; 95% CI = 0.27-0.82, P = 0.01), and severe acute exacerbation (aOR = 0.38; 95% CI = 0.23-0.63, P < 0.01) in COPD patients.</p><p><strong>Conclusions: </strong>Influenza vaccination reduced the risk of future acute exacerbations in patients with COPD. Clinician-led intensive health education can improve the influenza vaccination of outpatients with COPD, and clinicians and policymakers should pay attention to and apply this method.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04047"},"PeriodicalIF":4.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11886753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum: Akter E, Hossain AT, Ahamed B, Rahman MH, Hossain AKMT, Barua U, Islam MS, Manna RM, Hossain MA, Ara T, Usmani NG, Chandra P, Ameen S, Jabeen S, Ahmed A, Rahman TZ, Hassan MMU, Islam A, Barr BT, Rahman QS, Arifeen SE, Rahman AE. Excess mortality during COVID-19 and prediction of mortality in Bangladesh: an analysis based on death records in urban graveyards. J Glob Health. 2025;15:04050. 勘误:Akter E, Hossain AT, Ahmed B, Rahman MH, Hossain AKMT, Barua U, Islam MS, Manna RM, Hossain MA, Ara T, Usmani NG, Chandra P, Ameen S, Jabeen S, Ahmed A, Rahman TZ, Hassan MMU, Islam A, Barr BT, Rahman QS, Arifeen SE, Rahman AE孟加拉国2019冠状病毒病期间的超额死亡率和死亡率预测:基于城市墓地死亡记录的分析[J] .全球健康杂志,2015;15:04050。
IF 4.5 3区 医学
Journal of Global Health Pub Date : 2025-03-07 DOI: 10.7189/jogh.15.1504050err1
{"title":"Erratum: Akter E, Hossain AT, Ahamed B, Rahman MH, Hossain AKMT, Barua U, Islam MS, Manna RM, Hossain MA, Ara T, Usmani NG, Chandra P, Ameen S, Jabeen S, Ahmed A, Rahman TZ, Hassan MMU, Islam A, Barr BT, Rahman QS, Arifeen SE, Rahman AE. Excess mortality during COVID-19 and prediction of mortality in Bangladesh: an analysis based on death records in urban graveyards. J Glob Health. 2025;15:04050.","authors":"","doi":"10.7189/jogh.15.1504050err1","DOIUrl":"10.7189/jogh.15.1504050err1","url":null,"abstract":"","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"1504050err1"},"PeriodicalIF":4.5,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11900886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Excess mortality during COVID-19 and prediction of mortality in Bangladesh: an analysis based on death records in urban graveyards. 孟加拉国2019冠状病毒病期间的超额死亡率和死亡率预测:基于城市墓地死亡记录的分析
IF 4.5 3区 医学
Journal of Global Health Pub Date : 2025-02-28 DOI: 10.7189/jogh.15.04050
Ema Akter, Aniqa Tasnim Hossain, Bibek Ahamed, Md Hafizur Rahman, Tanvir Hossain Akm, Uchchash Barua, Md Shahidul Islam, Ridwana Maher Manna, Md Alamgir Hossain, Tasnu Ara, Nasimul Ghani Usmani, Pradip Chandra, Shafiqul Ameen, Sabrina Jabeen, Anisuddin Ahmed, Taufiq Zahidur Rahman, Mohammad Mamun-Ul-Hassan, Atiqul Islam, Beth Tippett Barr, Qazi Sadeq-Ur Rahman, Shams El Arifeen, Ahmed Ehsanur Rahman
{"title":"Excess mortality during COVID-19 and prediction of mortality in Bangladesh: an analysis based on death records in urban graveyards.","authors":"Ema Akter, Aniqa Tasnim Hossain, Bibek Ahamed, Md Hafizur Rahman, Tanvir Hossain Akm, Uchchash Barua, Md Shahidul Islam, Ridwana Maher Manna, Md Alamgir Hossain, Tasnu Ara, Nasimul Ghani Usmani, Pradip Chandra, Shafiqul Ameen, Sabrina Jabeen, Anisuddin Ahmed, Taufiq Zahidur Rahman, Mohammad Mamun-Ul-Hassan, Atiqul Islam, Beth Tippett Barr, Qazi Sadeq-Ur Rahman, Shams El Arifeen, Ahmed Ehsanur Rahman","doi":"10.7189/jogh.15.04050","DOIUrl":"10.7189/jogh.15.04050","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic significantly impacted global mortality, underscoring the need for reliable data to guide public health policy. In low- and middle-income countries, graveyard-based death records can offer valuable insights into COVID-19-related mortality, yet they remain limited. Additionally, data on mortality beyond the pandemic remains scarce as we approach the 2030 Sustainable Development Goals. We addressed this gap by using graveyard-based data to assess excess mortality during the pandemic (2020-23) and predict mortality trends through 2030.</p><p><strong>Methods: </strong>We analysed 70 585 deaths from six graveyards in Dhaka, Bangladesh, from January 2001 to December 2023. The data was divided into pre-COVID-19 (2001-19), peak-COVID-19 (2020-21), and end-of-COVID-19 (2022-23) phases. We assessed the excess mortality using the P-score and Bayesian approach. We estimated excess mortality with a log-linear Bayesian model and predicted death trends for 2024-30, reporting incidence rate ratio (IRR) with 95% credible intervals (CrI).</p><p><strong>Results: </strong>Overall, excess mortality was 69% greater in 2020 and 31% in 2023 compared to the 2018-19 average. The IRR for deaths during peak-COVID-19 was 1.66 times higher than pre-COVID-19 (95% CrI = 1.35-2.04). Neonates had significantly higher IRRs during both the peak (IRR = 1.45; 95% CrI = 1.02-2.05) and end-of-COVID-19 (IRR = 1.67; 95% CrI = 1.02-2.71). Individuals aged >40 years showed a significantly higher IRR during peak-COVID-19 (IRR = 1.79; 95% CrI = 1.46-2.18). Predictions using data between 2001-23 indicate rising mortality, with the number of adult deaths increasing from 3318 in 2023 to 5089 (95% CrI = 3871-6267) by 2030.</p><p><strong>Conclusions: </strong>We revealed a significant rise in mortality during the pandemic, with elevated death rates persisting at the end of the pandemic. Predictions indicate continued mortality increases through 2030, underscoring the pandemic's long-term health impacts. While further research is needed, these findings highlight the value of graveyard-based death registration data for tracking mortality trends and informing public health strategies.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04050"},"PeriodicalIF":4.5,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869516/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metabolomic characteristics and related pathways in patients with different severity of COVID-19: a systematic review and meta-analysis. 不同严重程度COVID-19患者的代谢组学特征及相关途径:系统综述和荟萃分析
IF 4.5 3区 医学
Journal of Global Health Pub Date : 2025-02-28 DOI: 10.7189/jogh.15.04056
Chenghao Bi, Junjie He, Yu Yuan, Shumei Che, Ting Cui, Li Ning, Yubo Li, Zhiying Dou, Liwen Han
{"title":"Metabolomic characteristics and related pathways in patients with different severity of COVID-19: a systematic review and meta-analysis.","authors":"Chenghao Bi, Junjie He, Yu Yuan, Shumei Che, Ting Cui, Li Ning, Yubo Li, Zhiying Dou, Liwen Han","doi":"10.7189/jogh.15.04056","DOIUrl":"10.7189/jogh.15.04056","url":null,"abstract":"<p><strong>Background: </strong>Despite advances in metabolomic research on COVID-19, existing studies have small sample sizes and few have comprehensively described the metabolic characteristics of patients with COVID-19 at each stage. In this systematic review, we aimed to summarise the similarities and differences of biomarkers in patients with COVID-19 of different severity and describe their metabolic characteristics at different stages.</p><p><strong>Methods: </strong>We retrieved studies from PubMed, Embase, Web of Science, and the Cochrane Library published by October 2022. We performed a meta-analysis on untargeted and targeted metabolomics research data, using the ratio of means as the effect size. We compared changes in metabolite levels between patients with varying severity and controls and investigated sources of heterogeneity through subgroup analyses and meta-regression analysis.</p><p><strong>Results: </strong>We included 22 cohorts from 21 studies, comprising 2421 participants, including COVID-19 patients of varying severity and healthy controls. We conducted meta-analysis and heterogeneity analysis on the 1058 metabolites included in the study. The results indicated that, compared to the healthy control group, 23 biomarkers were associated with mild cases (P < 0.05), 3 biomarkers with moderate cases (P < 0.05), and 37 biomarkers with severe cases (P < 0.05). Pathway enrichment analysis revealed significant disturbances in amino acid metabolism, aminoacyl-tRNA biosynthesis, primary bile acid biosynthesis, pantothenate and CoA biosynthesis, the tricarboxylic acid cycle, taurine and hypotaurine metabolism, and nitrogen metabolism in patients with mild, moderate, and severe disease. Additionally, we found that each severity stage exhibited unique metabolic patterns (all P < 0.05) and that the degree of metabolic dysregulation progressively worsened with increasing disease severity (P < 0.05).</p><p><strong>Conclusions: </strong>The results of our meta-analysis indicate the similarities and differences of biomarkers and metabolic characteristics of patients with different severity in COVID-19, thereby providing new pathways for the study of pathogenesis, the development precise treatment, and the formulation of comprehensive strategies.</p><p><strong>Registration: </strong>PROSPERO: CRD42022369937.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04056"},"PeriodicalIF":4.5,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869518/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design, development and implementation of a digital burial record-keeping and management system in Bangladesh. 孟加拉国数字埋葬记录保存和管理系统的设计、开发和实施。
IF 4.5 3区 医学
Journal of Global Health Pub Date : 2025-02-28 DOI: 10.7189/jogh.15.04086
Md Hafizur Rahman, Akm Tanvir Hossain, Uchchash Barua, Md Shahidul Islam, Ema Akter, Ridwana Maher Manna, Md Alamgir Hossain, Tasnu Ara, Nasimul Ghani Usmani, Pradip Chandra, Shafiqul Ameen, Sabrina Jabeen, Anisuddin Ahmed, Taufiq Zahidur Rahman, Mohammad Mamun-Ul-Hassan, Atiqul Islam, Beth Tippett Barr, Qazi Sadeq-Ur Rahman, Shams El Arifeen, Aniqa Tasnim Hossain, Ahmed Ehsanur Rahman
{"title":"Design, development and implementation of a digital burial record-keeping and management system in Bangladesh.","authors":"Md Hafizur Rahman, Akm Tanvir Hossain, Uchchash Barua, Md Shahidul Islam, Ema Akter, Ridwana Maher Manna, Md Alamgir Hossain, Tasnu Ara, Nasimul Ghani Usmani, Pradip Chandra, Shafiqul Ameen, Sabrina Jabeen, Anisuddin Ahmed, Taufiq Zahidur Rahman, Mohammad Mamun-Ul-Hassan, Atiqul Islam, Beth Tippett Barr, Qazi Sadeq-Ur Rahman, Shams El Arifeen, Aniqa Tasnim Hossain, Ahmed Ehsanur Rahman","doi":"10.7189/jogh.15.04086","DOIUrl":"10.7189/jogh.15.04086","url":null,"abstract":"<p><strong>Background: </strong>Digitalisation of death documentation in Bangladesh's graveyards is crucial for accurate mortality data and public health planning. Additionally, studying the usability, technology acceptance, and implementation aspects of the digital death record-keeping system, an innovative intervention that has not been previously explored, ensures the effectiveness, user adoption, and long-term sustainability. We designed, implemented, and evaluated a digital mortality surveillance system in graveyards in Dhaka city of Bangladesh.</p><p><strong>Methods: </strong>The study was conducted in six graveyards of the Dhaka North City Corporation (DNCC). First, we conducted formative research to understand the documentation process of the graveyard record-keeping and inform architecture for a digital record-keeping system. We then developed a digital record-keeping system for graveyard. A cross-sectional quantitative and qualitative study was conducted among web and app users, and graveyard managers and death records keepers.</p><p><strong>Results: </strong>A total of 200 app and web users and 14 record-keepers and managers participated. App and web users had high levels of system usability (88%) and found them easy to use (100%) and well-integrated (100%), with disagreement on complexity (100%), inconsistency (100%), and technical support needs (100%). These users had high technology acceptance and agreed the tools help accomplish tasks quickly (100%), improve performance (100%), and were easy to learn (100%). Digital death record-keepers reported using the system frequently (71%) but found it somewhat complex (14%) and not consistently easy to use (28%), with some reported that the systems were well integration (50%) and easy to learn (43%). While technology acceptance varied, death record keepers generally agreed that the system helps with quick task completion (50%) and performance improvement (57%), increase productivity (43%), enhance effectiveness (57%), and easy to use (50%). The digital death record-keeping system received mixed reactions, with younger, tech-savvy operators being optimistic, while older supervisors were sceptical and uncomfortable with technology. Additionally, the system was found to be feasible to an extent, particularly by data entry operators and graveyard managers.</p><p><strong>Conclusions: </strong>The digital death record-keeping system was generally well-received by app and web users for its usability and integration, though graveyard supervisor found it somewhat complex, with mixed reactions based on tech-savviness; overall, the system was deemed feasible and sustainable.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04086"},"PeriodicalIF":4.5,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894443/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causes and preventive measures for fire-related injuries in intensive care units: a systematic review. 重症监护病房火灾相关伤害的原因和预防措施:系统回顾。
IF 4.5 3区 医学
Journal of Global Health Pub Date : 2025-02-28 DOI: 10.7189/jogh.15.04043
JiaFang Wu, YuQing Yao, XiuLing Shang
{"title":"Causes and preventive measures for fire-related injuries in intensive care units: a systematic review.","authors":"JiaFang Wu, YuQing Yao, XiuLing Shang","doi":"10.7189/jogh.15.04043","DOIUrl":"10.7189/jogh.15.04043","url":null,"abstract":"<p><strong>Background: </strong>Intensive care unit (ICU) fires are a significant public health concern which often receives insufficient attention. However, they notoriously challenging to manage, with a high risk of casualties and substantial economic damage. Despite their severity, research on ICU fires remains scarce.</p><p><strong>Methods: </strong>In this systematic review, we queried PubMed, Cochrane, Embase, Web of Science, and Web of Baidu Academic for studies on ICU or hospital fires published from the inception of each database to 5 July 2024. We then narratively summarised the causes of ICU fires and the details of ICU fire prevention and evacuation.</p><p><strong>Results: </strong>We examined 2602 articles, of which 30 met our inclusion criteria. We summarised the causes and injuries of 18 ICU fires. The most common causes were electrical faults and oxygen cylinder faults, while the prevention and response strategies for ICU fires included regular maintenance of electrical and oxygen equipment, installation of automatic fire fighting systems, reasonable arrangement of patient beds, vertical and horizontal evacuation route planning, online and offline fire safety training, and intelligent evacuation simulation.</p><p><strong>Conclusions: </strong>We found that the primary causes of fires in ICUs are electrical malfunctions and oxygen-related incidents. It is essential to implement preventive measures such as regular inspection of electrical equipment, proper maintenance of wiring, and ensuring all oxygen systems are handled according to strict safety protocols. Additionally, ensuring that all ICU staff are adequately trained in emergency response protocols can significantly improve patient outcomes in the event of a fire.</p>","PeriodicalId":48734,"journal":{"name":"Journal of Global Health","volume":"15 ","pages":"04043"},"PeriodicalIF":4.5,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869519/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信