Anoushka Sinha, Rebecca K Tsevat, May Lin, Amanda E Downey, Sara M Buckelew
{"title":"\"Name it to tame it\": piloting a narrative medicine clinical intervention for adolescents and young adults with anorexia nervosa.","authors":"Anoushka Sinha, Rebecca K Tsevat, May Lin, Amanda E Downey, Sara M Buckelew","doi":"10.1186/s40337-026-01612-y","DOIUrl":"https://doi.org/10.1186/s40337-026-01612-y","url":null,"abstract":"<p><strong>Purpose: </strong>Anorexia nervosa (AN) is highly morbid, particularly in adolescence. Narrative-based interventions, which employ storytelling and self-reflection, have improved outcomes for patients with various conditions, but narrative medicine specifically has not been studied in adolescents with AN. This study piloted and evaluated a narrative medicine clinical intervention for adolescents and young adults (AYAs) with AN in an outpatient setting.</p><p><strong>Methods: </strong>Participants (ages 16-25), stable for outpatient care and in therapy for AN, were recruited through eating disorder clinics and community referrals. The clinical intervention consisted of a 6-week narrative medicine workshop series around themes including identity, embodiment, and resilience. Surveys assessed the intervention's acceptability, while clinical instruments assessed mental health and eating disorder symptoms; Wilcoxon signed-rank tests evaluated pre- and post-intervention differences. Semi-structured interviews elucidated participants' experiences of the intervention, and thematic analysis identified emergent themes.</p><p><strong>Results: </strong>Eight participants enrolled, and seven completed the study. The mean age was 21 ± 4 years, and 75% were female. All participants found the intervention highly acceptable. Mean PHQ-9 scores improved after the intervention (13 to 10, p = 0.046). In qualitative analysis, four themes emerged: gaining insight into one's condition, connecting over shared experiences, recognizing progress to be made, and viewing the workshops as a different type of treatment.</p><p><strong>Conclusions: </strong>This clinical intervention represents a novel application of narrative medicine for AYAs with AN. Narrative medicine was highly acceptable to participants, who derived meaning and social connection. Future studies may expand the intervention to larger, more diverse populations and further elucidate clinical outcomes and mechanisms for change.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov (Identifier: NCT06849830).</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A unified theory of restrictive and addictive eating: a life course model integrating generational transmission, neurodevelopmental risk, and ultra-processed food use disorder-a theoretical review.","authors":"David A Wiss, Alan C Logan","doi":"10.1186/s40337-026-01618-6","DOIUrl":"https://doi.org/10.1186/s40337-026-01618-6","url":null,"abstract":"<p><strong>Background: </strong>Eating disorders (EDs) and ultra-processed food use disorder (UPFUD) have traditionally been examined as separate entities, resulting in ongoing tension between two primary perspectives: (1) dietary restraint as the main driver of loss-of-control eating pathology, and (2) the influence of the contemporary food environment, combined with stressors, as the driver of addiction-like food consumption. Both perspectives acknowledge developmental trauma as a key predisposing factor.</p><p><strong>Methods: </strong>Drawing from relevant articles in the PubMed, Scopus, PsycINFO, and Google Scholar databases, this theoretical review combines evidence from trauma, neurodevelopmental, eating disorder, and addiction research. Relevant articles are synthesized to propose a unified life course model. The model integrates these perspectives by outlining developmental trajectories that originate from shared risk factors, diverge along distinct pathways, and may ultimately converge into similar behavioral presentations.</p><p><strong>Results: </strong>The Restrictive Eating Pathway typically progresses from generational trauma through parental symptoms of rigid/disordered eating patterns and/or obsessive-compulsive disorder (OCD) familial traits. In this context, adverse childhood experiences (ACEs) may further influence conditions conducive to dieting and eating disorder (ED) symptoms. This may culminate in pathologically restrictive eating patterns, which may include addictive processes. The Addictive Eating Pathway similarly progresses from generational trauma through parental symptoms of substance use disorders (SUDs) and/or attention-deficit/hyperactivity disorder (ADHD) familial traits. In this context, ACEs may further influence conditions conducive to hedonic eating, which can progress to UPFUD symptoms and other addictive processes, such as SUDs. Both pathways share generational trauma and ACEs as foundational risk factors. Familial OCD symptoms versus familial ADHD symptoms represent divergent predisposing legacies that can highlight differential risk when parental mental health assessment is available. Individual-level SUD frequently co-occurs in both pathways and, when present, may serve as a point of convergence or crossover, connecting or reflecting trajectories.</p><p><strong>Conclusions: </strong>This model emphasizes bidirectionality across constructs, conceptualizes eating pathology as a dimensional continuum rather than discrete categories, and acknowledges that individuals may transition between pathways throughout the lifespan. Implications for clinical assessment, treatment planning, prevention strategies, and the emerging fields of precision neurodiversity and metabolic psychiatry are discussed. This framework establishes a foundation for the understanding of mixed restrictive-addictive presentations and offers testable hypotheses for future longitudinal and mechanistic research.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anders Ohnstad, KariAnne Vrabel, Yngvild Sørebø Danielsen, Per-Einar Binder, Ingrid Dundas
{"title":"Self-compassion in flux: a four-year longitudinal study of intraindividual variations in self-compassion and disordered eating.","authors":"Anders Ohnstad, KariAnne Vrabel, Yngvild Sørebø Danielsen, Per-Einar Binder, Ingrid Dundas","doi":"10.1186/s40337-026-01605-x","DOIUrl":"https://doi.org/10.1186/s40337-026-01605-x","url":null,"abstract":"","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Matteo Aloi, Marianna Rania, Elvira Anna Carbone, Renato de Filippis, Ettore D'Onofrio, Lavinia Rotella, Daria Quirino, Antonino Carcione, Cristina Segura-Garcia
{"title":"Disentangling food addiction-related symptom profiles in anorexia nervosa: a latent class analysis and clinical implications.","authors":"Matteo Aloi, Marianna Rania, Elvira Anna Carbone, Renato de Filippis, Ettore D'Onofrio, Lavinia Rotella, Daria Quirino, Antonino Carcione, Cristina Segura-Garcia","doi":"10.1186/s40337-026-01611-z","DOIUrl":"https://doi.org/10.1186/s40337-026-01611-z","url":null,"abstract":"<p><strong>Background: </strong>The construct of Food Addiction (FA) has generated growing interest in the context of Anorexia Nervosa (AN), especially for its potential clinical implications. While AN is traditionally associated with restrictive eating patterns, recent findings suggest that FA symptoms may also be present in this population, complicating the clinical picture. This study aimed to explore FA symptomatology in individuals with AN using a person-centered approach and to identify psychological variables associated with different FA profiles.</p><p><strong>Methods: </strong>A sample of 202 individuals with a diagnosis of AN (including AN-R, AN-BP, and Atypical AN) completed the YFAS 2.0. A Latent Class Analysis (LCA) was performed to identify subgroups based on FA symptoms. Chi-square tests assessed associations between latent classes and AN subtypes. Binary logistic regressions explored psychological predictors of class membership, including eating psychopathology (EDE-Q), depressive symptoms (BDI-II), emotion dysregulation (DERS), and metacognitive abilities (MSAS).</p><p><strong>Results: </strong>LCA identified three latent classes: Class 1 (Addicted, 11.4%), characterized by high endorsement of FA symptoms; Class 2 (High-Risk, 33.7%), displaying moderate FA symptom severity; and Class 3 (Non-Addicted, 54.9%), showing minimal FA symptomatology. No significant association emerged between class membership and AN diagnostic subtype (χ²(4) = 3.085, p=.544). Logistic regressions revealed that impulsivity significantly predicted membership in the Addicted class (OR = 4.119, p<.05), while membership in the Non-Addicted class was associated with lower eating psychopathology, better metacognitive skills, and reduced impulsivity. Belonging to the High-Risk class was predicted by higher eating concern (OR = 2.618, p<.05), lower metacognition (OR=0.566, p<.05) and greater difficulties with emotional awareness (OR = 1.62; p<.01).</p><p><strong>Conclusions: </strong>These findings highlight the presence of distinct FA profiles within AN, independent of traditional diagnostic categories. The Addicted and High-Risk classes showed greater psychopathology and dysregulation. Notably, the High-Risk group also exhibited impaired metacognition, suggesting potential vulnerability despite moderate symptom expression. In contrast, the Non-Addicted class showed a more adaptive profile. LCA may support the development of personalized treatment strategies by targeting FA-related features, including interventions to improve emotion regulation and metacognitive functioning.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147724309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Vuillier, Ido Shalev, Rachel Louise Moseley, Florina Uzefovsky
{"title":"Feeling more than understanding: empathic disequilibrium and emotional reactivity in eating psychopathology.","authors":"Laura Vuillier, Ido Shalev, Rachel Louise Moseley, Florina Uzefovsky","doi":"10.1186/s40337-026-01600-2","DOIUrl":"https://doi.org/10.1186/s40337-026-01600-2","url":null,"abstract":"<p><strong>Background: </strong>Emotional dysregulation is a core feature of eating disorders, yet research has predominantly focused on intrapersonal emotion processes rather than interpersonal emotional mechanisms. Empathy comprises affective empathy (AE; feeling others' emotions) and cognitive empathy (CE; understanding others' emotions), with recent research suggesting that empathic disequilibrium-imbalances between AE and CE-may contribute to psychopathology. We hypothesized that empathic disequilibrium characterized by AE-dominance underlies emotional difficulties in eating disorders through heightened emotional reactivity.</p><p><strong>Methods: </strong>We conducted a two-phase investigation. Study 1 examined empathy and eating disorder symptoms in 345 undergraduate students using the Interpersonal Reactivity Index (IRI) and Eating Disorder Examination Questionnaire (EDE-Q). Study 2 replicated findings in 835 participants (including 103 with eating disorder diagnoses) and tested emotional reactivity as a mediator using the Emotional Reactivity Scale (ERS).</p><p><strong>Results: </strong>Both studies demonstrated consistent associations between empathic disequilibrium characterized by AE-dominance and eating disorder pathology (Study 1) and diagnosis (Study 2), with CE being unrelated to eating disorder symptoms. Mediation analyses revealed that emotional reactivity mediated the relationship between empathic disequilibrium and eating disorder symptoms, with sensitivity analyses supporting pathway robustness.</p><p><strong>Conclusions: </strong>This study provides first comprehensive evidence that empathic disequilibrium, rather than specific empathic deficits, represents a potential risk factor for eating psychopathology. AE-dominance appears to create emotional hyper-arousal when encountering others' emotions, which may be regulated using disordered eating behaviours. These findings challenge traditional empathy approaches in psychopathology and highlight the importance of interpersonal emotional processes in eating disorder conceptualization and treatment, opening new therapeutic avenues targeting both intrapersonal and interpersonal emotional functioning.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147718713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toward a triadic approach in eating disorders: investigating the contribution of the reflexive, affective and interoceptive systems in a clinical data cohort.","authors":"Flaudias Valentin, Gonthier Corentin, Cornil Aurélien, Seneque Maude, Lakritz Clara, Iceta Sylvain, Guillaume Sébastien","doi":"10.1186/s40337-026-01602-0","DOIUrl":"https://doi.org/10.1186/s40337-026-01602-0","url":null,"abstract":"<p><strong>Background: </strong>Eating disorders (ED) are disabling conditions increasingly conceptualized as addictive disorders. While food addiction (FA) is well documented in bulimia nervosa (BN) and binge-eating disorder (BED), its mechanisms in anorexia nervosa (AN) remain unclear. The triadic model of addiction-encompassing reflexive, affective, and interoceptive systems-offers a relevant framework to investigate FA across EDs. The current study aimed to test to what extent these three components of addiction contribute to FA in patients with ED.</p><p><strong>Methods: </strong>The sample included 115 patients (mean age = 28.41 years, SD = 11.64; 91% female) diagnosed with either AN (restrictive: n = 38; binge-eating/purging type: n = 32), BN (n = 29), or BED (n = 16). Participants completed the Emotional Appetite Questionnaire, the interoceptive subscale of the Eating Disorder Inventory-2, the Detail and Flexibility Questionnaire, and the Yale Food Addiction Scale 2.0. In the present analyses, FA was operationalized using the continuous total score reflecting FA symptom severity. Additional analyses using the symptom-count and diagnostic scoring procedures yielded comparable results. Linear and multinomial logistic regressions were used to test the associations between FA and the three systems, and their ability to distinguish diagnostic groups.</p><p><strong>Results: </strong>When considered separately, interoceptive difficulties (r = .54), negative emotions (r = .47), and cognitive inflexibility (r = .33) were all associated with higher FA (all ps < 0.001). However, in the joint model, only interoception (β = 0.39, p < .001) and negative emotions (β = 0.33, p = .005) remained significant predictors, whereas cognitive flexibility had no significant effect. These effects did not differ significantly between diagnostic groups. The affective system predicted diagnostic (χ²(3) = 21.78, p < .001), but the effect was inconsistent and the overall predictive value was modest (McFadden's R² = 0.11, classification accuracy = 50%).</p><p><strong>Conclusion: </strong>Interoceptive and affective systems appear to significantly predict FA across various ED; the reflexive system, as currently measured, seems to play a more limited role. These results highlight the need for more sensitive assessment tools and refined models of ED-related addictive dimensions. Trial Registration NCT03160443, first post 2017-05-03.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147692264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristin Stedal, Christina E Wierenga, Stephanie Knatz Peck, Laura Hill
{"title":"Bridging the gap between neuroscience and clinical practice: a review of the development of Temperament Based Therapy with Support (TBT-S).","authors":"Kristin Stedal, Christina E Wierenga, Stephanie Knatz Peck, Laura Hill","doi":"10.1186/s40337-026-01592-z","DOIUrl":"https://doi.org/10.1186/s40337-026-01592-z","url":null,"abstract":"<p><p>Temperament Based Therapy with Support (TBT-S) is an emerging, personalized treatment approach for eating disorders (EDs) that integrates patients' temperamental traits and neurobiological research into therapeutic strategies to reduce symptoms. While research on the efficacy of TBT-S is still in its infancy, the development of TBT-S as a treatment for EDs spans over two decades. The approach is unique in that it was formulated from neurobiological research, and utilizes treatment tools which were created collaboratively with individuals with lived experience. Hence, the aim of this review of the development of TBT-S is to share how clinical interventions can evolve from basic science through collaboration with the target population. The review provides a structured synthesis of how TBT-S progressed and explores the most current evidence and avenues for future research.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147677823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Collaboration in team outpatient eating disorder care: clinician's perspectives.","authors":"Megan Bray, Gabriella Heruc, Olivia R L Wright","doi":"10.1186/s40337-026-01593-y","DOIUrl":"https://doi.org/10.1186/s40337-026-01593-y","url":null,"abstract":"","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147663406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Introducing the Diathesis-Compassion Layered Care Model (DCLCM): an IPA study of dissociation and complex trauma in eating disorders in Iran.","authors":"Devendra Singh, Mohadeseh Bita","doi":"10.1186/s40337-026-01584-z","DOIUrl":"https://doi.org/10.1186/s40337-026-01584-z","url":null,"abstract":"<p><strong>Background: </strong>Eating disorders (EDs) frequently co-occur with trauma-related symptomatology, including dissociative experiences. While international research has examined associations between EDs and trauma frameworks such as the dissociative subtype of Post-Traumatic Stress Disorder and Complex Post-Traumatic Stress Disorder, little is known about how therapists in non-Western contexts conceptualize the trauma-dissociation-ED linkage or integrate trauma-informed and compassion-focused approaches in practice.</p><p><strong>Method: </strong>Interpretative Phenomenological Analysis (IPA) was applied to explore Iranian therapists' lived experiences in managing ED presentations involving dissociation comorbidity, with a focus on the therapeutic role of self-compassion. Semi-structured interviews were conducted with three therapists working with adolescents and young adults.</p><p><strong>Results: </strong>Analysis generated 11 superordinate and 58 subordinate themes. Findings were organized in five interlinked layers: Symptom Recognition, describing multifaceted ED presentations with dissociative features such as trance-like eating, emotional numbing, depersonalization, and identity disruption; Trauma and Vulnerability, highlighting early relational adversity, chronic invalidation, and dispositional traits including perfectionism and low self-esteem; Cultural and Social Context, reflecting body-surveillance norms, gendered expectations, family hierarchy, and stigma; Therapeutic interventions, capturing phased, safety-oriented, integrative treatment strategies; and Self-Compassion as a Transformative Healing Pathway, emphasizing compassion-focused processes for reducing shame and enhancing affect regulation. A Cross Layer Reflective Theme, appraised the utility of stress-vulnerability formulation in structuring case-conceptualisation and psychoeducation within Iranian practice. These themes informed the Diatheses-Compassion Layered Care Model (DCLCM), a five-layer conceptual framework grounded in therapists' narratives.</p><p><strong>Conclusions: </strong>Therapists frequently interpreted ED presentations involving dissociative features through trauma-informed and diatheses-stress lens. DCLCM offers a culturally embedded conceptual framework that integrates symptom recognition, trauma and vulnerability pathways, sociocultural context, therapeutic sequencing, and self-compassion processes. The model is intended to organize clinical reasoning in culturally sensitive settings and requires empirical evaluation in future research.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":" ","pages":""},"PeriodicalIF":4.5,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147655168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}