Journal of Eating Disorders最新文献

{"title":"Requests for support by pregnant women with eating disorder symptoms: a systematic literature review of qualitative studies.","authors":"Cecilia Brundin Pettersson, Klara Lundvik, Martina Isaksson, Mia Ramklint","doi":"10.1186/s40337-025-01251-9","DOIUrl":"https://doi.org/10.1186/s40337-025-01251-9","url":null,"abstract":"<p><strong>Background: </strong>During the peripartum period, four to 13 percent of women may be affected by eating disorders (ED). Previous reviews of qualitative studies in pregnant women with ED have mainly focused on the women's experiences during pregnancy and not on their expressed needs. This systematic review aimed to identify which types of support were requested by pregnant women with ED.</p><p><strong>Methods: </strong>The review was conducted in accordance with the \"Enhancing transparency in reporting the synthesis of qualitative research\" (ENTREQ) guidelines. Search for studies published between 1/1 2011- 14/3 2023 and 14/3 2023-9/1 2025, were performed in the following databases: PubMed, CINAHL, PsycInfo and Scopus. Studies were included if (1) the study population was pregnant women with ED symptoms /ED/ problems with food and eating, and (2) the study was an original qualitative study, and (3) the article was written in English. Rayyan, the AI-powered tool for systematic reviews, was used. Inclusion criteria were based on the SPICE-format. The CASP tool was used to assess quality in the included studies. Selected studies were read and critically appraised by two independent reviewers and a descriptive synthesis was conducted of expressed wishes for support based on quotes from the included studies. This review was preregistered in Prospero, 1/9 2023, (CRD42023456326).</p><p><strong>Results: </strong>Of 992 studies, only five fulfilled the inclusion criteria. From these studies three themes emerged: wish for support from health care, wish to get support from a partner and wish to use self-help strategies.</p><p><strong>Conclusion: </strong>This review found a knowledge gap regarding the type of support requested by pregnant women with ED symptoms. In this study, we aimed to explore the existing literature on the needs of support expressed by pregnant women with eating disorders. We reviewed studies published between 2011 and 2025, and found only five that partially addressed these needs. Three main themes emerged: wish for support, self-help strategies, and support from a partner. Our findings showed that the women expressed a desire for their midwives to have enough knowledge about eating disorders to bring up the topic and talk about it with them. We also identified a gap in the literature, highlight the need for more qualitative research to better understand the specific support these women want and need during pregnancy. The role of the partner in providing support should also be addressed in future research.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"71"},"PeriodicalIF":3.5,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12023643/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meanings of recovery and post-traumatic growth in people with lived experience of eating disorders: a qualitative study.","authors":"Chiara Tosi, Davide Patanè, Ludovica Natali, Valentina Meregalli, Valentina Cardi","doi":"10.1186/s40337-025-01258-2","DOIUrl":"https://doi.org/10.1186/s40337-025-01258-2","url":null,"abstract":"<p><strong>Background: </strong>Conceptualizations of recovery from an Eating Disorder (ED) have focused traditionally on symptom alleviation and restoration of physical health. In recent years, through patient involvement, this definition has been broadened to incorporate changes in psychological processes and overall wellbeing. This study used a qualitative approach to explore the meanings of recovery among people with lived experience of an ED. Areas of personal growth after the illness were explored, with reference to the theoretical framework of Post-Traumatic Growth (PTG).</p><p><strong>Methods: </strong>Nineteen participants (mean age 24.37; range: 18-50), who self-identified as recovered from an ED (mean time since recovery = 33.68 months, standard deviation = 31.67 months; range = 5-130 months), completed a demographic questionnaire and were asked to discuss their experiences of recovery and areas of PTG in a structured interview. Reflexive Thematic Analysis (TA) was used to identify common themes and sub themes.</p><p><strong>Results: </strong>Four overarching themes and 14 sub themes were identified. Recovery was defined as a non-linear process marked by changes in eating behaviours (e.g., greater flexibility), and more effective abilities to manage painful thoughts and emotions. Elements of PTG were included in the experience of recovery, particularly through a reconstituted, authentic and meaningful sense of self following the ED.</p><p><strong>Conclusions: </strong>People with lived experience of an ED provided a broad definition of recovery, which encompassed symptom restoration, as well as significant changes in psychological processes and elements of PTG. These findings have the potential to inform the development or refinement of recovery-focused treatments.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"70"},"PeriodicalIF":3.5,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12016052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A look in the mirror - body exposure in clinical practice.","authors":"Jessica Werthmann, Eva Naumann, Silja Vocks, Jennifer Svaldi, Andrea S Hartmann","doi":"10.1186/s40337-025-01262-6","DOIUrl":"https://doi.org/10.1186/s40337-025-01262-6","url":null,"abstract":"<p><strong>Background: </strong>The dissemination of evidence-based techniques is critical for the successful treatment of eating disorders in clinical practice. A growing number of studies suggests that body exposure is an effective technique to treat body image disturbance in eating disorders. However, the dissemination of body exposure among psychotherapists in clinical practice remains unclear.</p><p><strong>Methods: </strong>An online survey was conducted among licensed psychotherapists in Germany. The dissemination of body exposure in clinical practice, psychotherapists' characteristics (such as clinical training, attitudes towards exposure, confidence), and therapists' experiences with benefits and side-effects of body exposure were assessed.</p><p><strong>Results: </strong>Data of 230 psychotherapists were analysed. More than half of them (58.3%) applied body exposure in their clinical practice. Yet, body exposure was only offered to 37.3% of their eating disorder patients. Moreover, 56.7% of psychotherapists delivering body exposure indicated that they have not received any training in this technique. Self-reported confidence in delivering body exposure correlated significantly with the number of patients treated with body exposure. Psychotherapists who applied body exposure reported minor side-effects and that the majority of their patients profited from this technique.</p><p><strong>Conclusions: </strong>Our results offer insights into the dissemination of body exposure in clinical practice in Germany. Overall, body exposure is still underused considering the empirical evidence demonstrating the potential of body exposure to treat body image disturbances effectively. Moreover, with regard to potential barriers of using body exposure, our data suggest that training opportunities for clinicians may facilitate the dissemination of this technique in clinical practice.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"69"},"PeriodicalIF":3.5,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12007345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment outcomes for adolescent bulimia nervosa: a systematic scoping review of quantitative findings.","authors":"Madeleine Love, Julian Baudinet","doi":"10.1186/s40337-025-01236-8","DOIUrl":"https://doi.org/10.1186/s40337-025-01236-8","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to systematically scope the available quantitative evidence for adolescent Bulimia Nervosa (BN) interventions. Specifically, the study aimed to review psychological and behavioural symptoms outcomes, as well as changes in comorbid psychiatric and caregiver factors.</p><p><strong>Method: </strong>Five main and three grey literature databases were searched on 4th September 2024. Eligible peer-reviewed journal articles, dissertations and book chapters were included. Studies included children and adolescents with primary diagnoses of Bulimia Nervosa, Eating Disorder Not Otherwise Specified (EDNOS-BN) and Other Specified Feeding and Eating Disorder (OSFED-BN).</p><p><strong>Results: </strong>Findings from 18 studies (seven randomised controlled trials, three secondary analyses, eight single-arm studies) encompassing 710 participants were synthesised. All studies were conducted in the USA (10/18, 55.6%), UK (4/18, 22.2%), and mainland Europe (4/18, 22.2%). Most were conducted in an outpatient setting (14/18, 77.8%), with the remainder conducted in a day hospital (2/18, 11.1%), mixed outpatient/day hospital (1/18, 5.6%), or residential (1/18, 5.6%) setting. Family-focused therapies (10/18, 55.6%) and cognitive behavioural therapies (10/18, 55.6%) were most represented. Both were associated with improvements in BN psychopathology, comorbid difficulties and parent/caregiver factors. Weak evidence in favour of adjunctive therapies and Fluoxetine were reported.</p><p><strong>Discussion: </strong>There is a striking paucity in adolescent bulimia nervosa intervention research. Whilst family-focused and cognitive behavioural therapies show promise, the evidence base is relatively small. Most studies had small sample sizes and were conducted with predominately White, female participants. Very little data are available regarding parent/caregiver outcomes. Future research focusing on theory-driven mechanisms that target the broader presentation of BN are needed.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"68"},"PeriodicalIF":3.5,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12004555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143991542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An online educational resource addressing eating disorders during the menopause transition: a brief evaluation study.","authors":"Gemma Sharp, Lauren Bruce, Belinda Caldwell, Isabella McGrath, Susan R Davis, Alisha Randhawa","doi":"10.1186/s40337-025-01256-4","DOIUrl":"https://doi.org/10.1186/s40337-025-01256-4","url":null,"abstract":"<p><p>The biological, psychological and social changes that occur during the menopause transition can contribute to increased risk of eating disorder onset, re-emergence or exacerbation of a pre-existing eating disorder. Owing to a substantial lack of available evidence-based information addressing the intersection of eating disorders and menopause, we co-designed a novel online resource with people with a lived experience of an eating disorder during the menopause transition and other key stakeholders. We previously demonstrated preliminary acceptability and feasibility of this resource. The aim of our study was to conduct a brief evaluation of the online resource with \"real world\" users. In an approximately 7-month period during 2024, with the resource being hosted on Eating Disorders Victoria's LearnED platform, 279 people enrolled in the resource. The most common resource users were health professionals, particularly dietitians and psychologists. Of these users, almost 40% completed a brief online evaluation survey included within the resource which showed that participants were primarily seeking to understand the intersection of eating disorders and menopause as well as find services for support as their reasons for engaging with the resource. According to the evaluation results, the feedback from users was very positive - they had their learning needs met, were satisfied with the experience and would recommend the resource to others. Although more comprehensive resource evaluation should be completed in the future, our brief evaluation helps to pave the way for expansion of much needed research and resource development in the neglected field of eating disorders intersecting with menopause.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"67"},"PeriodicalIF":3.5,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11998430/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"United States-based practice guidelines for children and adolescents with eating disorders : Synthesis of clinical practice guidelines.","authors":"Cara Bohon, Daniel Le Grange, Evelyn Attia, Neville H Golden, Dori Steinberg","doi":"10.1186/s40337-025-01254-6","DOIUrl":"https://doi.org/10.1186/s40337-025-01254-6","url":null,"abstract":"<p><strong>Introduction: </strong>Several practice guidelines exist from professional organizations in the United States to support the assessment and management of eating disorders in children and adolescents. This manuscript synthesizes the key areas of overlap from these guidelines and provides directions for future research and alignment to improve care.</p><p><strong>Recommendations: </strong>Consistent screening for eating disorders in primary care is recommended to ensure early identification and referral to treatment. Outpatient treatment supported by families, including family based treatment, is the first line of care recommended by guidelines. Multidisciplinary treatment teams benefit patients in covering the variety of aspects of health that eating disorders impact, including mental health, nutritional health, and physical health. Patients may require hospitalization under certain medical criteria such as bradycardia or specific lab abnormalities.</p><p><strong>Conclusions: </strong>Guidelines show consensus on the importance of early identification and treatment access, involvement of family in treatment, and the use of a multidisciplinary treatment team. However, future work is needed to guide care of Avoidant/Restrictive Food Intake Disorder (ARFID), as well as the impact of weight inclusive care and the development of validated screening tools for children and adolescents for all eating disorders.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"66"},"PeriodicalIF":3.5,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body image flexibility and embodiment in eating disorders: a mixed-methods approach combining network analysis and pilot exposure protocol.","authors":"Paolo Meneguzzo, Chiara Cazzola, Francesca Buscaglia, Anna Pillan, Filippo Pettenuzzo, Patrizia Todisco","doi":"10.1186/s40337-025-01249-3","DOIUrl":"https://doi.org/10.1186/s40337-025-01249-3","url":null,"abstract":"<p><strong>Objective: </strong>Body image (BI) disturbances are central to the psychopathology of eating disorders (EDs), where body dissatisfaction and disembodiment often co-occur, exacerbating negative body image experiences. We aimed to examine body image flexibility and embodiment in women with EDs and a general population (GP) sample.</p><p><strong>Method: </strong>Data were collected from 172 participants, including 103 GP women and 69 women with EDs. Standardized questionnaires measuring body uneasiness, interoceptive awareness, and body image acceptance were administered. Additionally, a pilot group therapy intervention targeting body image concerns was evaluated with 24 ED participants.</p><p><strong>Results: </strong>Findings suggest that significant differences in embodiment-related features emerged (self-regulation and body trust), while both groups reported similar levels of interoceptive awareness. Network analysis revealed distinct patterns of partial correlations between variables within each group, with higher centrality for body image concerns and weight phobia in EDs. In contrast, the GP group exhibited stronger connections between embodiment features such as attention regulation and body image acceptance. The pilot intervention showed promise in improving body image flexibility and reducing body image concerns.</p><p><strong>Conclusions: </strong>These results underscore the importance of fostering body image flexibility and embodiment in the clinical treatment of EDs, suggesting potential pathways for enhancing therapeutic interventions.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"64"},"PeriodicalIF":3.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987398/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"'Do no harm' - the impact of an intervention for addictive eating on disordered eating behaviours in Australian adults: secondary analysis of the TRACE randomised controlled trial.","authors":"Janelle A Skinner, Mark Leary, Megan Whatnall, Phillipa J Hay, Susan J Paxton, Clare E Collins, Tracy L Burrows","doi":"10.1186/s40337-025-01241-x","DOIUrl":"https://doi.org/10.1186/s40337-025-01241-x","url":null,"abstract":"<p><strong>Background: </strong>Designing interventions to change addictive eating behaviours is a complex process and understanding the treatment effect on co-occurring disordered eating behaviours is of importance. This study aimed to explore treatment effects of the TRACE (Targeted Research for Addictive and Compulsive Eating) intervention for addictive eating on eating disorder psychopathology, binge eating, reward driven eating and grazing behaviours.</p><p><strong>Methods: </strong>This study involved secondary analysis of data from a randomised control trial among 175 participants (18-85 yrs) endorsing ≥ 3 Yale Food Addiction Scale (YFAS) symptoms who were randomly allocated to (1) active intervention, (2) passive intervention, or (3) control group. Change in YFAS, EDE-Q 6.0, Binge Eating Scale, RED-X5 and Short Inventory of Grazing scores were assessed at 3-months (immediate post-intervention) and 6-months (3-months post-intervention) follow-up.</p><p><strong>Results: </strong>Using Linear Mixed Models, from baseline to 3-months there was a significant reduction in eating disorder global scores in the active intervention [mean decrease - 0.6 (95% CI: -0.8, -0.4)], but not in the passive intervention [-0.2 (95% CI: -0.5, 0.1)] or control groups [-0.1 (95% CI: -0.3, 0.1)]. In the active and passive intervention groups there were significant reductions in reward driven eating [-3.8 (95% CI: -4.9, -2.7; -2.5 (95% CI: -3.9, -1.1), respectively], compulsive grazing (-1.8 (95% CI: -2.4, -1.3); -1.1 (95% CI: -1.7, -0.5), respectively] and non-compulsive grazing scores (-1.4 (95% CI: -1.9, -1.0); -1.1 (95% CI: -1.7, -0.4), respectively], but not in the control group. The reduction in binge eating scores over time was similar for all groups. The reduction in addictive eating symptoms from baseline to 3-months was positively associated with the reduction in eating disorder global scores, binge eating, reward driven eating and grazing behaviours (r_s ranged from 0.23 to 0.69).</p><p><strong>Conclusion: </strong>The dietitian-led TRACE intervention which adopted a weight-neutral, harm reduction approach for the management of addictive eating in adults demonstrated positive effects on some co-occurring disordered eating behaviours. Importantly the intervention did not cause any adverse changes in the eating disorder pathologies measured.</p><p><strong>Trial registration: </strong>Australia New Zealand Clinical Trial Registry ACTRN12621001079831.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"65"},"PeriodicalIF":3.5,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987355/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treating the individual: moving towards personalised eating disorder care.","authors":"Emma Bryant, Peta Marks, Kristi Griffiths, Stephanie Boulet, Melissa Pehlivan, Sarah Barakat, Stephen Touyz, Sarah Maguire","doi":"10.1186/s40337-025-01246-6","DOIUrl":"https://doi.org/10.1186/s40337-025-01246-6","url":null,"abstract":"<p><p>Eating disorders (EDs) are complex and heterogeneous conditions, which are often not resolved with conventional, manualised treatments. Arguments for the development of holistic, person-centred treatments accounting for individual variability have been mounting amongst researchers, clinicians and people with lived experience alike. This review explores the transformative potential of personalised medicine in ED care, emphasising the integration of precision diagnostics and tailored interventions based on individual genetic, biological, psychological and environmental profiles. Building on advancements in genomics, neurobiology, and computational technologies, it advocates for a shift from categorical diagnostic frameworks to symptom-based and dimensional approaches. The paper summarises emerging evidence supporting precision psychiatry, including the development of biomarkers, patient-reported outcomes, predictive modelling, and staging models, and discusses their application in ED research and clinical care. It highlights the utility of machine learning and idiographic statistical methods in optimising therapeutic outcomes and identifies key challenges, such as ethical considerations, scalability and implementation.</p>","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"63"},"PeriodicalIF":3.5,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11983806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144020280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Redefining prevention and early intervention to include longstanding and severe eating disorders.","authors":"James Leonard Downs","doi":"10.1186/s40337-025-01247-5","DOIUrl":"10.1186/s40337-025-01247-5","url":null,"abstract":"","PeriodicalId":48605,"journal":{"name":"Journal of Eating Disorders","volume":"13 1","pages":"61"},"PeriodicalIF":3.5,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11978142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143804587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}