npj Flexible Electronics最新文献

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Long-term stability strategies of deep brain flexible neural interface 脑深部柔性神经界面的长期稳定策略
IF 14.6 1区 材料科学
npj Flexible Electronics Pub Date : 2025-05-08 DOI: 10.1038/s41528-025-00410-x
Shiya Lv, Zhaojie Xu, Fan Mo, Yu Wang, Yiming Duan, Yaoyao Liu, Luyi Jing, Jin Shan, Qianli Jia, Mingchuan Wang, Siyu Zhang, Yu Liu, Juntao Liu, Jinping Luo, Yirong Wu, Mixia Wang, Yilin Song, Xinxia Cai
{"title":"Long-term stability strategies of deep brain flexible neural interface","authors":"Shiya Lv, Zhaojie Xu, Fan Mo, Yu Wang, Yiming Duan, Yaoyao Liu, Luyi Jing, Jin Shan, Qianli Jia, Mingchuan Wang, Siyu Zhang, Yu Liu, Juntao Liu, Jinping Luo, Yirong Wu, Mixia Wang, Yilin Song, Xinxia Cai","doi":"10.1038/s41528-025-00410-x","DOIUrl":"https://doi.org/10.1038/s41528-025-00410-x","url":null,"abstract":"<p>Flexible deep brain neural interfaces, as an important research direction in the field of neural engineering, have broad application prospects in areas such as neural signal detection, treatment of neurological diseases, and intelligent control systems. However, chronic inflammatory responses caused by long-term implantation and the resulting electrode failure seriously hinder the clinical development of this technology. This review systematically explores the long-term stability issues of flexible deep brain neural interfaces, with a focus on analyzing the synergistic optimization of electrode geometric morphology and implantation strategies in regulating inflammatory responses. Additionally, this paper delves into innovative strategies, such as passive enhancement of biocompatibility through electrode surface functionalization and active inhibition of inflammation through drug-controlled release systems, offering new technical paths to extend electrode lifespan. By integrating and reviewing existing innovative methods for deep brain flexible electrodes, this study provides an important theoretical foundation and technical guidance for the development of high-stability neural interface devices.</p>","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":"63 1","pages":""},"PeriodicalIF":14.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vertical textile microfluidics: advancing on-garment sweat sampling for real-time biosensing 垂直纺织微流体:推进服装汗液采样实时生物传感
IF 14.6 1区 材料科学
npj Flexible Electronics Pub Date : 2025-05-08 DOI: 10.1038/s41528-025-00416-5
Marina Galliani, Esma Ismailova, Pooya Azizian, Anatolii Makhinia, Joan M. Cabot
{"title":"Vertical textile microfluidics: advancing on-garment sweat sampling for real-time biosensing","authors":"Marina Galliani, Esma Ismailova, Pooya Azizian, Anatolii Makhinia, Joan M. Cabot","doi":"10.1038/s41528-025-00416-5","DOIUrl":"https://doi.org/10.1038/s41528-025-00416-5","url":null,"abstract":"<p>The identification of novel physiological biomarkers in sweat requires real-time sampling and analysis. Here, we present the microfabrication of epidermal microfluidics within textiles via stereolithography (SLA) 3D printing. Flexible SLA resin defines impermeable fluid-guiding microstructures in textile microfluidic modules. Their vertical stacking reduces device footprint and required sample volume, and facilitates on-body fluid collection, storage, and transport. Embedded internal modules act as a reservoir and injection valve, releasing a defined volume of sweat to the sensing unit. The pressure gradient across the modules provides a vertically distributed, capillary-driven sweat flow, guided by the wicking power of the textile structure. Their full integration into apparels offers non-cumulative flow through an extended air-liquid interface, ensuring continuous sweat transfer and evaporation. For real-time sweat analysis, we use a remotely screen-printed potassium (K<sup>+</sup>) ion detector. This modular approach provides fabric-integrated, mechanically ergonomic microfluidics with multi-parameter detection through rapid additive manufacturing for advanced point-of-care diagnostics.</p>","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":"12 1","pages":""},"PeriodicalIF":14.6,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
End-of-Life usefulness of degradation by products from transient electronics 瞬态电子产品降解的终寿命有用性
IF 14.6 1区 材料科学
npj Flexible Electronics Pub Date : 2025-05-07 DOI: 10.1038/s41528-025-00411-w
Sofia Sandhu, Ravinder Dahiya
{"title":"End-of-Life usefulness of degradation by products from transient electronics","authors":"Sofia Sandhu, Ravinder Dahiya","doi":"10.1038/s41528-025-00411-w","DOIUrl":"https://doi.org/10.1038/s41528-025-00411-w","url":null,"abstract":"<p>Transient electronics, comprising of degradable devices that disintegrate and disappear after their operational life, has received considerable interest in recent years because of the concerns related to the rapidly growing electronic waste (e-waste). However, the degradability or biodegradability of electronic devices alone is insufficient to ascertain environmental safety. The evaluation of the nature of degradation by-products is also essential to assess the environmental impact of a degradable device. Herein, we investigate systematically the hydrolytic degradation by-products of two different types of devices viz. a capacitive pressure sensor and a photodetector, using liquid chromatograph mass spectrometry. The findings reveal that, despite the inherent degradability of constituent materials used in an electronic device, the released by-products can be toxic or could be complex molecules with unknown chemistry such as carcinogenic or contain almost non-degradable polystyrene derivatives/microplastic (e.g., from PEDOT:PSS), or have copper complexes resulting from degraded silk fibroin and poly(ethylene oxide) mass fragments. This analysis underlines the need for careful selection and reassessment of materials employed in transient electronics, as an important factor, to mitigate the end-of-life issues associated with electronics and its environmental impact.</p>","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":"37 1","pages":""},"PeriodicalIF":14.6,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Engineering flexible dopamine biosensors: blended EGylated conjugated and radical polymers in organic electrochemical transistors 工程柔性多巴胺生物传感器:有机电化学晶体管中混合的乙二醇化共轭聚合物和自由基聚合物
IF 14.6 1区 材料科学
npj Flexible Electronics Pub Date : 2025-05-02 DOI: 10.1038/s41528-025-00412-9
Dinh Cung Tien Nguyen, Quyen Vu Thi, Quynh H. Nguyen, Jaehyoung Ko, Hoyeon Lee, Bryan Boudouris, Seung-Yeol Jeon, Yongho Joo
{"title":"Engineering flexible dopamine biosensors: blended EGylated conjugated and radical polymers in organic electrochemical transistors","authors":"Dinh Cung Tien Nguyen, Quyen Vu Thi, Quynh H. Nguyen, Jaehyoung Ko, Hoyeon Lee, Bryan Boudouris, Seung-Yeol Jeon, Yongho Joo","doi":"10.1038/s41528-025-00412-9","DOIUrl":"https://doi.org/10.1038/s41528-025-00412-9","url":null,"abstract":"<p>We demonstrate an enhancement in the figure of merit (μC*) of a flexible organic electrochemical transistor (OECT) and its dopamine (DA) biosensor by blending various open-shell, non-conjugated radical polymers featuring nitroxide radical active sites as pendant groups with closed-shell, ethylene glycol (EG)-functionalized conjugated polymers as a macromolecular active layer system. The precisely controlled ionic transport of the OECT by the radical polymer modulated the doping level of the EGylated polymer, ensuring well-regulated redox activity and resulting in <i>μC</i>* values exceeding 192 F V<sup>-</sup>¹ cm<sup>-</sup>¹ s<sup>-</sup>¹, along with an on/off ratio of 10<sup>4</sup>. Additionally, we achieved an ultrasensitive detection limit for DA at the clinically relevant level of 1 pM, along with exceptional specificity, effectively distinguishing DA even in the presence of a substantial excess of interfering substances. These findings underscore the potential of a systematic design approach for developing an advanced, flexible OECT-based biosensor platform through the strategic selection and processing of open- and closed-shell macromolecules.</p>","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":"55 1","pages":""},"PeriodicalIF":14.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143901455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advanced textile-based OLEDs utilizing parylene-C planarization for enhanced flexibility and stability in true wearing displays 先进的基于纺织品的oled,利用聚苯乙烯- c平面化,增强了真正佩戴显示器的灵活性和稳定性
IF 14.6 1区 材料科学
npj Flexible Electronics Pub Date : 2025-05-02 DOI: 10.1038/s41528-025-00413-8
Ha-Eun Cho, Myeong Ji Kim, Jaehyeock Chang, Jingi An, Yunha Na, Seungyeop Choi, So Yeong Jeong, Kyung Cheol Choi
{"title":"Advanced textile-based OLEDs utilizing parylene-C planarization for enhanced flexibility and stability in true wearing displays","authors":"Ha-Eun Cho, Myeong Ji Kim, Jaehyeock Chang, Jingi An, Yunha Na, Seungyeop Choi, So Yeong Jeong, Kyung Cheol Choi","doi":"10.1038/s41528-025-00413-8","DOIUrl":"https://doi.org/10.1038/s41528-025-00413-8","url":null,"abstract":"<p>Wearable electronic devices are gaining popularity, with textiles serving as a highly flexible platform. Organic electronic devices, known for their ultra-thin and flexible properties, are also attracting attention. This study presents a reliable fabrication method for textile-based organic light-emitting diodes (OLEDs) using a parylene-C planarization layer. The process creates a smooth surface with sub-nanometer roughness through a simple transfer and thermal annealing, forming a self-supporting planarization layer without immersion in water or chemicals. The parylene-C film enhances crystallinity and stiffness, ensuring mechanical stability. The fabricated OLEDs operate reliably under extreme deformations such as bending and wrinkling. Additionally, a 3×3 textile-based OLED array was demonstrated for display applications, and a scarf-based OLED verified its potential in fashion. This approach highlights the seamless integration of advanced electronics into textiles, offering promising applications across industries and marking a significant advancement in wearable display technology.</p>","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":"15 1","pages":""},"PeriodicalIF":14.6,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143901456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tactile near-sensor computing systems incorporating hourglass-shaped microstructured capacitive sensors for bio-realistic energy efficiency 触觉近传感器计算系统,结合沙漏形微结构电容传感器,实现生物逼真的能源效率
IF 14.6 1区 材料科学
npj Flexible Electronics Pub Date : 2025-05-01 DOI: 10.1038/s41528-025-00415-6
Jae-Yeong Cho, Seong Eun Kim, Chang-Jae Beak, Jihwan Lee, Wonjeong Suh, Bo-Yeon Lee, Sin-Hyung Lee
{"title":"Tactile near-sensor computing systems incorporating hourglass-shaped microstructured capacitive sensors for bio-realistic energy efficiency","authors":"Jae-Yeong Cho, Seong Eun Kim, Chang-Jae Beak, Jihwan Lee, Wonjeong Suh, Bo-Yeon Lee, Sin-Hyung Lee","doi":"10.1038/s41528-025-00415-6","DOIUrl":"https://doi.org/10.1038/s41528-025-00415-6","url":null,"abstract":"<p>Bio-inspired near-sensor computing, which integrates sensing and processing functions, presents a promising strategy to enhance efficiency and reduce latency in such applications. Here, we introduce tactile sensory nerve systems with biologically realistic energy efficiency, utilizing starfish-inspired capacitive pressure sensors integrated with flexible memristors. These starfish-inspired sensors, with their high aspect ratio (~3) and stress-focusing, hourglass-shaped dielectric microstructures, enable highly sensitive tactile detection across a broad pressure range, effectively mimicking the properties of human skin. Artificial tactile sensory nerves, which integrate the capacitive sensor with a flexible memristor exhibiting synaptic plasticity, function reliably as energy-efficient near-sensor computing systems by bio-realistically transducing mechanical stimuli into transient electrical signals. The developed system operates as both an artificial nociceptor and a tactile near-sensor computing unit, with energy consumption approaching biological levels at approximately 140 pJ and 2.2 fJ, respectively. This neuro-inspired localized computing strategy offers a physical platform for advanced smart user interface applications.</p>","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":"274 1","pages":""},"PeriodicalIF":14.6,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143893600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A magnetic soft robotic system for intelligent bladder volume control 一种用于智能膀胱体积控制的磁性软机器人系统
IF 14.6 1区 材料科学
npj Flexible Electronics Pub Date : 2025-04-26 DOI: 10.1038/s41528-025-00401-y
Qiyun Hu, Zikun Wu, Ye Tian, Jiaxin Wang, Zhangqi Pan, Yang Yu, Yifan Cheng, Yueying Yang, Hanchuan Tang, Jianfeng Zang
{"title":"A magnetic soft robotic system for intelligent bladder volume control","authors":"Qiyun Hu, Zikun Wu, Ye Tian, Jiaxin Wang, Zhangqi Pan, Yang Yu, Yifan Cheng, Yueying Yang, Hanchuan Tang, Jianfeng Zang","doi":"10.1038/s41528-025-00401-y","DOIUrl":"https://doi.org/10.1038/s41528-025-00401-y","url":null,"abstract":"<p>Underactive bladder (UAB) patients experience straining to void and typically cannot sense bladder fullness. Previous closed-loop bladder volume control systems are limited in neurogenic UAB patients and face infection risk due to wired connections. Here, we propose an intelligent bladder volume control system (IBCS) combining an implantable meshed magnetic soft robot (MMR) with a wearable magnetic field sensor. The MMR, tightly sutured to the bladder, compresses the bladder to facilitate urination under magnetic actuation, achieving a voiding efficiency of 94.8%. The wearable magnetic field sensor outside the abdomen achieves continuous and wireless monitoring of bladder volume with a 4.8% error in time. The MMR was validated on a UAB pig model, demonstrating a pressure increase of up to 33 cmH<sub>2</sub>O and voiding efficiency of over 83%. Our IBCS provides a biocompatible solution for wireless and continuous bladder volume management by integrating wearable sensors and magnetic robotics.</p>","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":"4 1","pages":""},"PeriodicalIF":14.6,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143875891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flexible perovskite light-emitting diodes: recent progress, applications and challenges 柔性钙钛矿发光二极管:最新进展、应用和挑战
IF 14.6 1区 材料科学
npj Flexible Electronics Pub Date : 2025-04-21 DOI: 10.1038/s41528-025-00408-5
Ying Li, Tingyi Gao, Ziquan He, Chenxi Shen, Siqian Zhou, Mingze Li, Daquan Zhang, Qianpeng Zhang, Yu Fu, Xiaoliang Mo, Zhaoyu Zhang, Wengang Bi, Zhiyong Fan
{"title":"Flexible perovskite light-emitting diodes: recent progress, applications and challenges","authors":"Ying Li, Tingyi Gao, Ziquan He, Chenxi Shen, Siqian Zhou, Mingze Li, Daquan Zhang, Qianpeng Zhang, Yu Fu, Xiaoliang Mo, Zhaoyu Zhang, Wengang Bi, Zhiyong Fan","doi":"10.1038/s41528-025-00408-5","DOIUrl":"https://doi.org/10.1038/s41528-025-00408-5","url":null,"abstract":"<p>Significant progress has been made in perovskite light-emitting diodes (PeLEDs) over the past decade, with external quantum efficiencies (EQEs) exceeding 30% for green and red emissions, and 20% for blue emissions. However, the performance and device area of flexible PeLEDs remains constrained due to issues such as crack formation and short circuits that occur during device deformation. These challenges limit their applicability in flexible, stretchable, and wearable displays and lighting solutions. This review systematically summarizes recent advancements in flexible PeLEDs, focusing on various strategies to improve their flexibility and performance. We first discuss the use of flexible substrates and electrodes in these devices. Next, we examine the fabrication methods and the mechanical and optoelectronic properties of different perovskite materials used in flexible PeLEDs, including three-dimensional (3D) thin films, low-dimensional nanomaterials, and perovskite/polymer composites. Finally, we highlight the extensive applications of flexible PeLEDs in wearable optoelectronics and provide an outlook on the future development of high-performance flexible PeLEDs to facilitate their commercialization.</p>","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":"56 1","pages":""},"PeriodicalIF":14.6,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143853224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanically stable screen-printed flexible perovskite solar cells via selective self-assembled siloxane coupling agents 通过选择性自组装硅氧烷偶联剂实现机械稳定的丝网印刷柔性过氧化物太阳能电池
IF 14.6 1区 材料科学
npj Flexible Electronics Pub Date : 2025-04-11 DOI: 10.1038/s41528-025-00407-6
Meiru Duan, Jinxian Yang, Tai Li, Junlin Wen, Biyun Ren, Kaiyu Wang, Yingdong Xia, Hui Zhang, Yonghua Chen
{"title":"Mechanically stable screen-printed flexible perovskite solar cells via selective self-assembled siloxane coupling agents","authors":"Meiru Duan, Jinxian Yang, Tai Li, Junlin Wen, Biyun Ren, Kaiyu Wang, Yingdong Xia, Hui Zhang, Yonghua Chen","doi":"10.1038/s41528-025-00407-6","DOIUrl":"https://doi.org/10.1038/s41528-025-00407-6","url":null,"abstract":"<p>Owing to unique advantages of patternability and high substrate compatibility, screen-printing allows for the fabrication of flexible perovskite solar cells (f-PSCs) with designable device patterns, while the defective and fragile contact at the buried interface seriously restricted the device performance. Herein, a series of siloxane coupling agents (SCAs) with different ending groups i.e., –SH, –NH<sub>2</sub>, and –CN were incorporated at the SnO<sub>2</sub>/perovskite interface, which can selectively interact with MA<sup>+</sup> and Pb<sup>2+</sup> via hydrogen and coordination bonding, respectively. It was revealed that the selection of (3-Cyanopropyl)Triethoxysilane (CN-PTES) can regulate perovskite crystallization with accelerated nucleation and retarded crystal growth, leading to improved crystallinity with released residual lattice strain. Moreover, the incorporated CN-PTES aligned the energy structure of the underlying SnO<sub>2</sub> and boosted the interfacial adhesion between perovskite and SnO<sub>2</sub>, resulting in facilitated electron extraction and enhanced interfacial fracture energy. Consequently, the first screen-printed f-PSCs with improved mechanical resistance were finally obtained.</p>","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":"14 1","pages":""},"PeriodicalIF":14.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143822499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hexagonal metal complex based mechanically robust transparent ultrathin gold µECoG for electro-optical neural interfaces 基于六方金属复合物的机械坚固透明超薄金 µECoG 用于电光神经接口
IF 14.6 1区 材料科学
npj Flexible Electronics Pub Date : 2025-04-11 DOI: 10.1038/s41528-025-00403-w
Duhee Kim, Murali Bissannagari, Boil Kim, Nari Hong, Jaeu Park, Hyeongtae Lim, Junhee Lee, Jungha Lee, Yoon Kyoung Kim, Youngjae Cho, Kwang Lee, Junghyup Lee, Jong-Hyeok Yoon, Jae Eun Jang, David Tsai, Sanghoon Lee, Hyuk-Jun Kwon, Han Kyoung Choe, Hongki Kang
{"title":"Hexagonal metal complex based mechanically robust transparent ultrathin gold µECoG for electro-optical neural interfaces","authors":"Duhee Kim, Murali Bissannagari, Boil Kim, Nari Hong, Jaeu Park, Hyeongtae Lim, Junhee Lee, Jungha Lee, Yoon Kyoung Kim, Youngjae Cho, Kwang Lee, Junghyup Lee, Jong-Hyeok Yoon, Jae Eun Jang, David Tsai, Sanghoon Lee, Hyuk-Jun Kwon, Han Kyoung Choe, Hongki Kang","doi":"10.1038/s41528-025-00403-w","DOIUrl":"https://doi.org/10.1038/s41528-025-00403-w","url":null,"abstract":"<p>Transparent electro-optical neural interfacing technologies offer simultaneous high-spatial-resolution microscopic imaging, and high-temporal-resolution electrical recording and stimulation. However, fabricating transparent, flexible, and mechanically robust neural electrodes with high electrochemical performance remains challenging. In this study, we fabricated transparent (72.7% at 570 nm), mechanically robust (0.05% resistance change after 50k bending cycles) ultrathin Au microelectrodes for micro-electrocorticography (µECoG) using a hexadentate metal-polymer ligand bonding with an EDTA/PSS seed layer. These transparent µECoG arrays, fabricated with biocompatible gold, exhibit excellent electrochemical properties (0.73 Ω·cm<sup>2</sup>) for neural recording and stimulation with long-term stability. We recorded brain surface waves in vivo, maintaining a low baseline noise and a high signal-to-noise ratio during acute and two-week recordings. In addition, we successfully performed optogenetic modulation without light-induced artifacts at 7.32 mW/mm<sup>2</sup> laser power density. This approach shows great potential for scalable, implantable neural electrodes and wearable optoelectronic devices in digital healthcare systems.</p>","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":"183 1","pages":""},"PeriodicalIF":14.6,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143822836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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