npj Flexible Electronics最新文献

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Real-time deep learning-assisted mechano-acoustic system for respiratory diagnosis and multifunctional classification 用于呼吸诊断和多功能分类的实时深度学习辅助机械声学系统
IF 12.3 1区 材料科学
npj Flexible Electronics Pub Date : 2024-10-21 DOI: 10.1038/s41528-024-00355-7
Hee Kyu Lee, Sang Uk Park, Sunga Kong, Heyin Ryu, Hyun Bin Kim, Sang Hoon Lee, Danbee Kang, Sun Hye Shin, Ki Jun Yu, Juhee Cho, Joohoon Kang, Il Yong Chun, Hye Yun Park, Sang Min Won
{"title":"Real-time deep learning-assisted mechano-acoustic system for respiratory diagnosis and multifunctional classification","authors":"Hee Kyu Lee, Sang Uk Park, Sunga Kong, Heyin Ryu, Hyun Bin Kim, Sang Hoon Lee, Danbee Kang, Sun Hye Shin, Ki Jun Yu, Juhee Cho, Joohoon Kang, Il Yong Chun, Hye Yun Park, Sang Min Won","doi":"10.1038/s41528-024-00355-7","DOIUrl":"10.1038/s41528-024-00355-7","url":null,"abstract":"Epidermally mounted sensors using triaxial accelerometers have been previously used to monitor physiological processes with the implementation of machine learning (ML) algorithm interfaces. The findings from these previous studies have established a strong foundation for the analysis of high-resolution, intricate signals, typically through frequency domain conversion. In this study we integrate a wireless mechano-acoustic sensor with a multi-modal deep learning system for the real-time analysis of signals emitted by the laryngeal prominence area of the thyroid cartilage at frequency ranges up to 1 kHz. This interface provides real-time data visualization and communication with the ML server, creating a system that assesses severity of chronic obstructive pulmonary disease and analyzes the user’s speech patterns.","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":" ","pages":"1-12"},"PeriodicalIF":12.3,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41528-024-00355-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142452075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Correction: Stretchable wireless optoelectronic synergistic patches for effective wound healing 作者更正:用于伤口有效愈合的可伸缩无线光电协同贴片
IF 12.3 1区 材料科学
npj Flexible Electronics Pub Date : 2024-10-21 DOI: 10.1038/s41528-024-00358-4
Qian Wang, Siyuan Cai, Guang Yao, Liyuan Zhang, Wenhao Lou, Youxin Chen, Qingqing Li, Maowen Xie, Xingyi Gan, Chenzheng Zhou, Taisong Pan, Min Gao, Kangning Zhao, Zhen Cai, Yuan Lin
{"title":"Author Correction: Stretchable wireless optoelectronic synergistic patches for effective wound healing","authors":"Qian Wang, Siyuan Cai, Guang Yao, Liyuan Zhang, Wenhao Lou, Youxin Chen, Qingqing Li, Maowen Xie, Xingyi Gan, Chenzheng Zhou, Taisong Pan, Min Gao, Kangning Zhao, Zhen Cai, Yuan Lin","doi":"10.1038/s41528-024-00358-4","DOIUrl":"10.1038/s41528-024-00358-4","url":null,"abstract":"","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":" ","pages":"1-1"},"PeriodicalIF":12.3,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41528-024-00358-4.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142451822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metallization of leaf-derived lignocellulose scaffolds for high-performance flexible electronics and oligodynamic disinfection 将源自树叶的木质纤维素支架金属化,用于高性能柔性电子器件和低聚消毒剂
IF 12.3 1区 材料科学
npj Flexible Electronics Pub Date : 2024-10-18 DOI: 10.1038/s41528-024-00353-9
Rakesh Rajendran Nair, Mihai Nita-Lazar, Valeriu Robert Badescu, Cristina Iftode, Jakob Wolansky, Tobias Antrack, Hans Kleemann, Karl Leo
{"title":"Metallization of leaf-derived lignocellulose scaffolds for high-performance flexible electronics and oligodynamic disinfection","authors":"Rakesh Rajendran Nair, Mihai Nita-Lazar, Valeriu Robert Badescu, Cristina Iftode, Jakob Wolansky, Tobias Antrack, Hans Kleemann, Karl Leo","doi":"10.1038/s41528-024-00353-9","DOIUrl":"10.1038/s41528-024-00353-9","url":null,"abstract":"Vascular tubules in natural leaves form quasi-fractal networks that can be metallized. Traditional metallization techniques for these lignocellulose structures are complex, involving metal sputtering, nanoparticle solutions, or multiple chemical pretreatments. Here we present a novel, facile, and reliable method for metallizing leaf-derived lignocellulose scaffolds using silver microparticles. The method achieves properties on-par with the state-of-the-art, such as broadband optical transmittance of over 80%, sheet resistances below 1 Ω/sq., and a current-carrying capacity exceeding 6 A over a 2.5 × 2.5 cm² quasi-fractal electrode. We also demonstrate copper electrodeposition as a cost-effective approach towards fabricating such conductive, biomimetic quasi-fractals. Additionally, we show that these metallized structures can effectively eliminate pathogenic microorganisms like fecal coliforms and E. coli, which are bacterial indicators of microbiological contamination of water. We finally show that these oligodynamic properties can be significantly enhanced with a small externally applied voltage, indicating the noteworthy potential of such structures for water purification and pollution control.","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":" ","pages":"1-8"},"PeriodicalIF":12.3,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41528-024-00353-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142447854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identification of gas-liquid two-phase flow patterns based on flexible ultrasound array and machine learning 基于柔性超声阵列和机器学习的气液两相流模式识别
IF 12.3 1区 材料科学
npj Flexible Electronics Pub Date : 2024-10-18 DOI: 10.1038/s41528-024-00354-8
Hang Liu, Jinhui Fan, Xinyi Lin, Kai Lin, Suhao Wang, Songyuan Liu, Fei Wang, Jizhou Song
{"title":"Identification of gas-liquid two-phase flow patterns based on flexible ultrasound array and machine learning","authors":"Hang Liu, Jinhui Fan, Xinyi Lin, Kai Lin, Suhao Wang, Songyuan Liu, Fei Wang, Jizhou Song","doi":"10.1038/s41528-024-00354-8","DOIUrl":"10.1038/s41528-024-00354-8","url":null,"abstract":"Ultrasound technology has been recognized as the mainstream approach for the identification of gas-liquid two-phase flow patterns, which holds great value in engineering domain. However, commercial rigid probes are bulky, limiting their adaptability to curved surfaces. Here, we propose a strategy for autonomous identification of flow patterns based on flexible ultrasound array and machine learning. The array features high-performance 1–3 piezoelectric composite material, stretchable serpentine wires, soft Eco-flex layers and a polydimethylsiloxane (PDMS) adhesive layer. The resulting ultrasound array exhibits excellent electromechanical characteristics and offers a large stretchability for an intimate interfacial contact to curved surface without the need of ultrasound coupling agents. We demonstrated that the flexible ultrasound array combined with machine learning can accurately identify gas-liquid two-phase flow patterns, in a circular pipeline. This work presents an effective tool for recognizing gas-liquid two-phase flow patterns, offering engineering opportunities in petroleum extraction and natural gas transportation.","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":" ","pages":"1-10"},"PeriodicalIF":12.3,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41528-024-00354-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142449626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Active-type piezoelectric smart textiles with antifouling performance for pathogenic control 用于病原体控制的具有防污性能的主动型压电智能纺织品
IF 12.3 1区 材料科学
npj Flexible Electronics Pub Date : 2024-10-09 DOI: 10.1038/s41528-024-00350-y
Su Eon Lee, Hanna Lee, Jang Hwan Kim, Jae Chul Park, Sooah Kyung, Hayoung Choi, Su Hyun Baek, Jun Hyun Park, Sohyun Park, Jeong-Min Kim, Hye-Jun Jo, Seung Hyeon Cho, Jiwoong Kim, Hojun Kim, Seung Ho Han, Jun Kyun Oh, Bong Hoon Kim
{"title":"Active-type piezoelectric smart textiles with antifouling performance for pathogenic control","authors":"Su Eon Lee, Hanna Lee, Jang Hwan Kim, Jae Chul Park, Sooah Kyung, Hayoung Choi, Su Hyun Baek, Jun Hyun Park, Sohyun Park, Jeong-Min Kim, Hye-Jun Jo, Seung Hyeon Cho, Jiwoong Kim, Hojun Kim, Seung Ho Han, Jun Kyun Oh, Bong Hoon Kim","doi":"10.1038/s41528-024-00350-y","DOIUrl":"10.1038/s41528-024-00350-y","url":null,"abstract":"Recently, an investigation into preventive measures for coronavirus disease 2019 (COVID-19) has garnered considerable attention. Consequently, strategies for the proactive prevention of viral pathogens have also attracted significant interest in the field of wearable devices and electronic textiles research, particularly due to their potential applications in personal protective equipment. In this study, we introduce smart textiles designed with optimized piezoelectric devices that exhibit antifouling performance against microorganisms and actively inactivate viruses. These active-type smart textiles, which incorporate advanced lead zirconate titanate (PZT) ceramics, a stretchable interconnector array, and polymeric fabric, demonstrate effective antifouling capabilities, detaching approximately 90% of Escherichia coli and 75% of SARS-CoV-2. Furthermore, they inactivate viruses, releasing ~26.8 ng of N protein from ruptured SARS-CoV-2, using ultrasonic waves within the wearable platform. Experimental results show that piezoelectric smart textiles significantly reduce the spread of COVID-19 by leveraging the electrical and acoustic properties of PZT ceramics.","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":" ","pages":"1-10"},"PeriodicalIF":12.3,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41528-024-00350-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142385005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Stretchable wireless optoelectronic synergistic patches for effective wound healing 用于伤口有效愈合的可伸缩无线光电协同贴片
IF 12.3 1区 材料科学
npj Flexible Electronics Pub Date : 2024-10-08 DOI: 10.1038/s41528-024-00351-x
Qian Wang, Siyuan Cai, Guang Yao, Liyuan Zhang, Wenhao Lou, Youxin Chen, Qingqing Li, Maowen Xie, Xingyi Gan, Chenzheng Zhou, Taisong Pan, Min Gao, Kangning Zhao, Zhen Cai, Yuan Lin
{"title":"Stretchable wireless optoelectronic synergistic patches for effective wound healing","authors":"Qian Wang, Siyuan Cai, Guang Yao, Liyuan Zhang, Wenhao Lou, Youxin Chen, Qingqing Li, Maowen Xie, Xingyi Gan, Chenzheng Zhou, Taisong Pan, Min Gao, Kangning Zhao, Zhen Cai, Yuan Lin","doi":"10.1038/s41528-024-00351-x","DOIUrl":"10.1038/s41528-024-00351-x","url":null,"abstract":"Physiotherapies play a crucial role in noninvasive tissue engineering for wound healing. However, challenges such as the implementation of complex interventions and unsatisfactory treatment outcomes impede widespread application. Here, we proposed a stretchable and wirelessly-powered optoelectronic synergistic patch with a dual-layer serpentine wireless receiver circuit to drive the optoelectronic modulation component. Optimized structure and impedance matching enable the patch to seamlessly attach to irregular skin surfaces and operate robustly over a 30% tensile strain range. Based on Sprague-Dawley rat wound model. The wound closure rate of the optoelectronic synergistic group significantly outperformed both monointervention and blank control groups. Mechanistically, optoelectronic synergistic intervention enhances the secretion of vascular endothelial marker proteins and growth factors, and stabilizes mitochondrial function during oxidative stress. Overall, the scalable amalgamation of flexible electronics, wireless transmission, and synergistic interventions promise to improve wound care.","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":" ","pages":"1-10"},"PeriodicalIF":12.3,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41528-024-00351-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142384432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Facile strategy for uniform gold coating on silver nanowires embedded PDMS for soft electronics 在嵌入 PDMS 的银纳米线上均匀镀金以制造软电子器件的简便策略
IF 12.3 1区 材料科学
npj Flexible Electronics Pub Date : 2024-10-04 DOI: 10.1038/s41528-024-00349-5
Haechan Park, Sehyun Kim, Juyeong Lee, Kwangmin Kim, Hanah Na, Yeeun Kim, Daeun Kim, Donghyung Shin, BongSoo Kim, Kyoseung Sim
{"title":"Facile strategy for uniform gold coating on silver nanowires embedded PDMS for soft electronics","authors":"Haechan Park, Sehyun Kim, Juyeong Lee, Kwangmin Kim, Hanah Na, Yeeun Kim, Daeun Kim, Donghyung Shin, BongSoo Kim, Kyoseung Sim","doi":"10.1038/s41528-024-00349-5","DOIUrl":"10.1038/s41528-024-00349-5","url":null,"abstract":"Silver nanowires-embedded polydimethylsiloxane (AgNWs/PDMS) electrodes are promising components for various soft electronics, but face energy mismatch with organic semiconductors. Attempts at galvanic replacement, involving spontaneous gold (Au) formation on the electrodes, often result in non-uniform and particulate Au coatings, compromising device performance and stability. In this study, we introduce a novel approach for achieving a uniform and complete Au coating on AgNWs/PDMS electrodes by adding NaCl to the Au complex solution. This addition slows down the galvanic replacement process and prevents precipitation, enabling a uniform and complete Au coating on the AgNWs surface. Such coating significantly reduces contact resistance (RC), thereby enhancing the electrical characteristics of p-type organic transistors. Furthermore, the development of high-performance, fully soft organic transistors was achieved incorporating an organic semiconductor-elastomer blend. Additionally, reliable, mechanically stable soft glucose sensor was developed, taking advantage of the complete Au coating, which protects against oxidation during the glucose sensing process.","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":" ","pages":"1-10"},"PeriodicalIF":12.3,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41528-024-00349-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142374210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Self-adaptive epidermal blood flow sensor for high-flux vascular access monitoring of hemodialysis patients 用于血液透析患者高通量血管通路监测的自适应表皮血流传感器
IF 12.3 1区 材料科学
npj Flexible Electronics Pub Date : 2024-10-02 DOI: 10.1038/s41528-024-00342-y
Yuqi Tian, Kai Yang, Yicong Wang, Jie Wang, Andrea S. Carlini, Zhinan Zhang, Yujun Deng, Jinyun Tan, Linfa Peng, Bo Yu, Zhongqin Lin
{"title":"Self-adaptive epidermal blood flow sensor for high-flux vascular access monitoring of hemodialysis patients","authors":"Yuqi Tian, Kai Yang, Yicong Wang, Jie Wang, Andrea S. Carlini, Zhinan Zhang, Yujun Deng, Jinyun Tan, Linfa Peng, Bo Yu, Zhongqin Lin","doi":"10.1038/s41528-024-00342-y","DOIUrl":"10.1038/s41528-024-00342-y","url":null,"abstract":"Well-functioning vascular access (VA) is essential for hemodialysis treatment in patients with end-stage renal disease (ESRD). However, continuous and accurate monitoring of blood flow to assess high-flux VA during hospitalization or at home is not feasible for either clinical instruments or wearable sensors. Here, we report the design and preclinical validation of a high-precision, long-term, epidermal blood flow sensor that self-adapts to unavoidable sensor-mounting deviations on the skin and is compatible with individual tissue differences. Specifically, the technology is based on thermal dissipation of the skin, and improves the signal-to-error ratio surpassing 4 times when measuring high-flux blood (100–600 mL/min). In preclinical validation, the sensor is compared with the Doppler ultrasound and demonstrate a blood flow resolution of 10–50 mL/min. Furthermore, it is highly-integrated and wearable, measuring 36 × 50 mm2. The sensor paves the way for accurate, convenient, high-flux blood monitoring, offering significant potential to extend the lives of patients with ESRD.","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":" ","pages":"1-14"},"PeriodicalIF":12.3,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41528-024-00342-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flexible electronic-photonic 3D integration from ultrathin polymer chiplets 利用超薄聚合物芯片实现柔性电子-光子三维集成
IF 12.3 1区 材料科学
npj Flexible Electronics Pub Date : 2024-10-01 DOI: 10.1038/s41528-024-00344-w
Yunxiang Huang, Gen Li, Tianyu Bai, Yieljae Shin, Xiaoxin Wang, Alexander Ian More, Pierre Boucher, Chandramouli Chandrasekaran, Jifeng Liu, Hui Fang
{"title":"Flexible electronic-photonic 3D integration from ultrathin polymer chiplets","authors":"Yunxiang Huang, Gen Li, Tianyu Bai, Yieljae Shin, Xiaoxin Wang, Alexander Ian More, Pierre Boucher, Chandramouli Chandrasekaran, Jifeng Liu, Hui Fang","doi":"10.1038/s41528-024-00344-w","DOIUrl":"10.1038/s41528-024-00344-w","url":null,"abstract":"Integrating flexible electronics and photonics can create revolutionary technologies, but combining these components on a single polymer device has been difficult, particularly for high-volume manufacturing. Here, we present a robust chiplet-level heterogeneous integration of polymer-based circuits (CHIP), where ultrathin polymer electronic and optoelectronic chiplets are vertically bonded at room temperature and shaped into application-specific forms with monolithic Input/Output (I/O). This process was used to develop a flexible 3D integrated optrode with high-density microelectrodes for electrical recording, micro light-emitting diodes (μLEDs) for optogenetic stimulation, temperature sensors for bio-safe operations, and shielding designs to prevent optoelectronic artifacts. CHIP enables simple, high-yield, and scalable 3D integration, double-sided area utilization, and miniaturization of connection I/O. Systematic characterization demonstrated the scheme’s success and also identified frequency-dependent origins of optoelectronic artifacts. We envision CHIP being applied to numerous polymer-based devices for a wide range of applications.","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":" ","pages":"1-11"},"PeriodicalIF":12.3,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41528-024-00344-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142360074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Body-worn and self-powered flexible optoelectronic device for metronomic photodynamic therapy 用于节拍光动力疗法的体戴式自供电柔性光电设备
IF 12.3 1区 材料科学
npj Flexible Electronics Pub Date : 2024-09-30 DOI: 10.1038/s41528-024-00345-9
Jianhong Zhang, Xinhui Mao, Qingyan Jia, Renhao Nie, Yangyang Gao, Kai Tao, Honglong Chang, Peng Li, Wei Huang
{"title":"Body-worn and self-powered flexible optoelectronic device for metronomic photodynamic therapy","authors":"Jianhong Zhang, Xinhui Mao, Qingyan Jia, Renhao Nie, Yangyang Gao, Kai Tao, Honglong Chang, Peng Li, Wei Huang","doi":"10.1038/s41528-024-00345-9","DOIUrl":"10.1038/s41528-024-00345-9","url":null,"abstract":"Photodynamic therapy (PDT) as a clinical method relies on appropriate light delivery to activate photosensitizers, usually necessitates the utilization of cumbersome surgical instruments and high irradiation intensity, along with the requirement for hospitalization. To extend the applicability of PDT beyond hospital for better patient mobility, we design a wearable and self-powered metronomic PDT (mPDT) system for chronic wound infection treatment. A flexible alternative current electroluminescent (ACEL) device is constructed through sandwiching an emissive layer between conductive hydrogel electrodes. This ACEL device works as a therapeutic patch by loading photosensitizer (PS) in its bottom hydrogel electrode, thus aviods the intravenous administration to patients. Under the triboelectric nanogenerator generated AC pulse, the electroluminescence produced from emissive layer can be absorbed by the PS-loaded electrode to generate reactive oxygen species for mPDT. Benefited from its arbitrary tailorability, this device can be customized into on-demand shapes and sizes. Using diabetic infected wound as a model condition, this ACEL mPDT device effectively eliminates drug-resistant bacteria and accelerates wound healing. Thus, the body-worn optoelectronic device successfully avoids the utilization of extracorporeal physical light and power sources, providing a promising strategy for convenient, user-friendly, and prolonged treatment of superficial diseases.","PeriodicalId":48528,"journal":{"name":"npj Flexible Electronics","volume":" ","pages":"1-14"},"PeriodicalIF":12.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41528-024-00345-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142329694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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