Pan African Medical JournalPub Date : 2024-06-14eCollection Date: 2024-01-01DOI: 10.11604/pamj.2024.48.61.39880
André Arsène Bita Fouda, Verdiane Félécité Metagne Kengne, Dieudonné Adiogo, Léon Jules Owona Manga
{"title":"[Refusal and hesitation regarding vaccination against COVID-19 in Douala, Cameroon].","authors":"André Arsène Bita Fouda, Verdiane Félécité Metagne Kengne, Dieudonné Adiogo, Léon Jules Owona Manga","doi":"10.11604/pamj.2024.48.61.39880","DOIUrl":"10.11604/pamj.2024.48.61.39880","url":null,"abstract":"<p><strong>Introduction: </strong>vaccination is one of the strategies the World Health Organization recommends to reduce the burden of COVID-19. However, many African countries like Cameroon have low COVID-19 vaccination coverage. The purpose of this study was to investigate the reasons for the refusal of the population of the city of Douala to be vaccinated against COVID-19.</p><p><strong>Methods: </strong>we conducted a cross-sectional and analytical study in Douala from February 10 to May 31, 2022. Participants, aged at least 21 years and residing in the city of Douala, were interviewed. Associations between the variables of interest were measured using Chi-square and Fisher tests, with a 95% confidence interval.</p><p><strong>Results: </strong>a total of 1555 people were included in the study. Only 168 (11%) had been vaccinated. The proportion of vaccine refusal was high, with 711 (45.7%) refusing, 640 participants (41.1%) hesitating, and 204 people (13.2%) being in favor of COVID-19 vaccination. The main reasons for refusing anti-COVID-19 vaccination were fear of adverse effects (406; 44.8%), lack of information about vaccines (331; 36.5%), and lack of confidence (302; 33.3%). Factors associated with vaccine refusal were religion (p=0.026) and level of education (p=0.002).</p><p><strong>Conclusion: </strong>this study revealed low COVID-19 vaccination coverage in Douala, with a significant proportion of refusal and hesitation towards vaccination. Communication strategies should take into account the reasons and factors associated with refusal.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11444086/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pan African Medical JournalPub Date : 2024-06-14eCollection Date: 2024-01-01DOI: 10.11604/pamj.2024.48.60.37918
Innocent Okoacha, Patrick Ifeanyi Okonta, Osamudia Okhionkpamwonyi
{"title":"A randomized comparative study of serial membrane sweeping at term for vaginal birth after caesarean section in two tertiary hospitals in Delta State.","authors":"Innocent Okoacha, Patrick Ifeanyi Okonta, Osamudia Okhionkpamwonyi","doi":"10.11604/pamj.2024.48.60.37918","DOIUrl":"10.11604/pamj.2024.48.60.37918","url":null,"abstract":"<p><strong>Introduction: </strong>postdate pregnant women with one previous caesarean section that are planned for vaginal birth after caesarean sections are faced with adverse pregnancy outcomes. This trial was conducted to determine the effect of serial membrane sweeping from 38 weeks gestation in pregnant women planned for vaginal birth after caesarean section.</p><p><strong>Methods: </strong>this randomized controlled trial (RCT) was conducted on 90 women at 38 weeks with one previous caesarean section. In the study group, membranes sweeping commenced at 38 weeks and repeated weekly till labour onset. If no labour onset at 41 weeks and 3 days, elective caesarean section was done. In the control group, patients awaited labour onset till 41 weeks and 3 days, after which elective caesarean section was done. Data collected were analyzed using the Statistical Package for Social Sciences (SPSS ver. 22). All analyses were done at p<0.05.</p><p><strong>Results: </strong>labour onset before 41 weeks and 3 days was statistically significantly higher in the study group compared to the control group (RR= 1.5; 95% CI: 1.1 - 2.0; P=0.006). Likewise, successful vaginal birth after caesarean section was statistically significantly higher in the study group (RR=1.7; 95% CI: 1.2-2.5; P = 0.001).</p><p><strong>Conclusion: </strong>serial membrane sweeping from 38 weeks gestation has significant beneficial effect on labour onset and successful vaginal delivery in women with one previous caesarean section.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419578/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metastatic myxoid round cell liposarcoma of the buttock: a case report.","authors":"Niare Ndour, Mamadou Sarr, Assane Diop, Mamadou Diouldé Kanté, Coumba Ndiaye, Astou Diouf, Fatou Diagne, Moussa Diallo, Fatimata Ly","doi":"10.11604/pamj.2024.48.56.40400","DOIUrl":"10.11604/pamj.2024.48.56.40400","url":null,"abstract":"<p><p>Liposarcoma is a rare primitive mesenchymal tumor, developed at the expense of adipose tissue and with a preferential location in the thigh. We report an observation of liposarcoma in the buttock. A 56-year-old man, presented with a tumor of the right buttock for 2 years. Examination revealed an inflammatory, ulcerated tumor in the upper-external quadrant of the right buttock, measuring about 8 cm. Bilateral inguinal adenopathies were associated. The diagnostic hypotheses were: a squamous cell carcinoma, a cutaneous lymphoma, and cutaneous metastases. An anatomical examination confirmed the diagnosis of myxoid round-cell liposarcoma. The extension work-up appeared compatible with secondary pleuropulmonary, hepatic, cutaneous, and lymph node neoplastic localizations. The patient was treated with chemotherapy with the Adriamycin-carboplatin protocol. The evolution was rapidly fatal after a few weeks after the first course of chemotherapy. It should be evoked in front of any ulcerated tumor of the buttock.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pan African Medical JournalPub Date : 2024-06-13eCollection Date: 2024-01-01DOI: 10.11604/pamj.2024.48.59.43884
Jay Dinesh Bhanushali
{"title":"A unique finding of Henoch-Schönlein purpura in adults.","authors":"Jay Dinesh Bhanushali","doi":"10.11604/pamj.2024.48.59.43884","DOIUrl":"10.11604/pamj.2024.48.59.43884","url":null,"abstract":"","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pan African Medical JournalPub Date : 2024-06-12eCollection Date: 2024-01-01DOI: 10.11604/pamj.2024.48.55.43770
Fabrice Humura, Theogene Uwizeyimana, Josiane Kabayundo, Eric Rucogoza
{"title":"Closing gaps in the oxygen supply chain in nations with limited resources.","authors":"Fabrice Humura, Theogene Uwizeyimana, Josiane Kabayundo, Eric Rucogoza","doi":"10.11604/pamj.2024.48.55.43770","DOIUrl":"10.11604/pamj.2024.48.55.43770","url":null,"abstract":"<p><p>Oxygen is an essential medication used across all levels of healthcare for conditions such as surgery, trauma, heart failure, asthma, pneumonia, and maternal and child care. Despite its critical importance and inclusion on the World Health Organization's list of essential medicines, many low- and middle-income countries (LMICs) face significant challenges in providing adequate oxygen supplies. These challenges are exacerbated by the COVID-19 pandemic, which has drastically increased global oxygen demand. This paper examines the current challenges and advancements in the oxygen supply chain within LMICs, focusing on availability, infrastructure, and usage. It highlights the innovative solutions being implemented to improve oxygen access and offers strategic recommendations for enhancing oxygen delivery and maintenance in resource-limited settings.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pan African Medical JournalPub Date : 2024-06-11eCollection Date: 2024-01-01DOI: 10.11604/pamj.2024.48.54.37911
Vincent Ganu, Oluwakemi Oladele, Emmanuella Amankwa, Rafiq Okine, Peter Puplampu
{"title":"Clinico-epidemiological characteristics of adolescents and young adults living with HIV in Ghana.","authors":"Vincent Ganu, Oluwakemi Oladele, Emmanuella Amankwa, Rafiq Okine, Peter Puplampu","doi":"10.11604/pamj.2024.48.54.37911","DOIUrl":"10.11604/pamj.2024.48.54.37911","url":null,"abstract":"<p><strong>Introduction: </strong>sub-Saharan Africa is experiencing a boom in the number of adolescents and young adults living with HIV (AYALHIV). Existing HIV intervention programs are mainly for children and adults living with HIV, with little attention paid to AYALHIV. Characterizing this population is necessary for planning, and designing, AYALHIV-centered HIV intervention programs.</p><p><strong>Methods: </strong>a retrospective single-center, hospital-based chart review was conducted at the largest HIV clinic in Ghana. We examined routinely collected data for AYALHIV (aged 10-24 years) on antiretroviral therapy (ART) for at least 1 year and in active care from 1<sup>st</sup> January to 31<sup>st</sup> December 2019. Data was collected using a structured data extraction form. The Chi-square and the Student´s t-test were used to compare characteristics between adolescents and young adults.</p><p><strong>Results: </strong>of 252 AYALHIV, 68% (172/252) were adolescents with a median age of 17 years (IQR 13-19); 32% were young adults with a median age of 22 years (IQR: 20-24). Most (56.7% (143/252)) AYALHIV were female. Almost 40% were orphans. Eighty-six percent of AYALHIV had HIV type I infection. The commonest mode of HIV acquisition among adolescents was vertical transmission (70.5%) and that among young adults was via unprotected sex (31.3%). Eighty-eight percent (88%) of AYALHIV were on non-nucleoside reverse transcriptase inhibitors-based regimen. The viral suppression rate among AYALHIV was 78%.</p><p><strong>Conclusion: </strong>the study shows there is a growing population of AYALHIV most of which are adolescents. About two-fifths were orphans. Policymakers and HIV programs should ensure AYALHIV-centred interventions are developed for this vulnerable population.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142309720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pan African Medical JournalPub Date : 2024-06-10eCollection Date: 2024-01-01DOI: 10.11604/pamj.2024.48.53.35130
Gabriela Venade, Catarina Almeida, Nídia Oliveira, Luis Costa Matos
{"title":"Schmidt´s syndrome found by tan: a case report.","authors":"Gabriela Venade, Catarina Almeida, Nídia Oliveira, Luis Costa Matos","doi":"10.11604/pamj.2024.48.53.35130","DOIUrl":"10.11604/pamj.2024.48.53.35130","url":null,"abstract":"<p><p>Addison´s disease can form part of type 2 autoimmune polyglandular syndrome. The article reports the case of a 41-year-old female patient with hypothyroidism and vitiligo, who came to the emergency department complaining of asthenia that had worsened in recent months, as well as anorexia, nausea, and weight loss (6 kg in a year). Cutaneous hyperpigmentation was the main finding on physical examination, together with vitiligo lesions on the face, hands, and armpits. Further study revealed a low serum cortisol level, normal urine-free cortisol, and an elevated adrenocorticotropic hormone (ACTH). Antiperoxidase antibodies and 17-alpha-hidroxylase antibodies were both positive. Treatment was started with prednisolone and fludrocortisone, and a good clinical response was obtained. This case report aims to draw attention to the high level of clinical suspicion required to diagnose Addison´s disease and the need to screen actively for other potentially associated autoimmune diseases that may be associated.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aplasia cutis congenita of the trunk in a newborn: a rare case report.","authors":"El Mouloua Ahmed, Aballa Najoua, Foura Salma, Kamili Elouafi Elaouni, Fouraiji Karima, Oulad Saiad Mohamed","doi":"10.11604/pamj.2024.48.52.43784","DOIUrl":"10.11604/pamj.2024.48.52.43784","url":null,"abstract":"<p><p>Aplasia cutis congenita (ACC) is a rare congenital disorder defined as a congenital skin defect, characterized by the absence of all skin layers at birth. The most frequent presentation is a small erythematous ulcerated or scar-like alopecic ectodermal lesion on the scalp vertex. However, extensive cutis aplasia of the trunk is extremely uncommon. Clinical and radiological evaluation defined the appropriate treatment. We herein report a rare case of a large aplasia cutis congenita of the trunk occurring in a male newborn managed with sulfadiazine silver 1% dressing, complete healing was achieved in about a month. The report highlights that conservative treatment is a highly effective and practical option for managing non-scalp extensive ACC.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11419577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142308794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}