Indian Journal of Critical Care Medicine最新文献

{"title":"Message from the New Editor-in-Chief: Continuity and Change, Impact and Visibility.","authors":"Jigeeshu V Divatia","doi":"10.5005/jp-journals-10071-24976","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24976","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"401"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative Recovery from a Cardiac Anesthesiologists' Perspective.","authors":"Rohan Magoon, Poonam Malhotra Kapoor","doi":"10.5005/jp-journals-10071-24944","DOIUrl":"10.5005/jp-journals-10071-24944","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"466"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101986/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Response: 5'-Nucleotidase for Predicting Snakebite Outcomes-A Biomarker Breakthrough?","authors":"Shivakumar Belur","doi":"10.5005/jp-journals-10071-24965","DOIUrl":"10.5005/jp-journals-10071-24965","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"465"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ventilator-associated Pneumonia: A Persistent Menace in the ICU.","authors":"Jeetendra Sharma, Shakya Mohanty","doi":"10.5005/jp-journals-10071-24945","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24945","url":null,"abstract":"<p><p>Sharma J, Mohanty S. Ventilator-associated Pneumonia: A Persistent Menace in the ICU. Indian J Crit Care Med 2025;29(4):285-286.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"285-286"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Position Statement of ISCCM on Intrahospital Transport of Critically Ill Patients.","authors":"Kapil G Zirpe, Anand M Tiwari, Atul P Kulkarni, Deepak Govil, Srinivas Samavedam, Jeetendra Sharma, Subhal B Dixit, Manish Munjal, Sharmili Sinha, Yogendra P Singh, Arunachala Sumalatha, Swarna D Kaurgayala, Shweta R Chandankhede, Syed Ahmed, Susruta Bandyopadhyay, Sunil Karanth, Vijay Mishra, Anand Dongre, Bikram Gupta, Pragyan Routray, Rakesh Nongthombam, Bharat Jagiasi, Pradip Bhattacharya, Subhash Todi","doi":"10.5005/jp-journals-10071-24939","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24939","url":null,"abstract":"<p><strong>Background and purpose: </strong>Intrahospital transport (IHT) of critically ill patients is essential for diagnostic and therapeutic indications, requiring thorough assessment and careful preparation of patients, staff, and equipment throughout the process. Variability in practices among hospitals can affect patient safety and may result in adverse events (AEs). This position statement is designed to provide guidance to multidisciplinary critical care teams in the adoption of evidence-based recommendations aimed at mitigating risks and improving safety during patient transport.</p><p><strong>Method: </strong>This position statement has been drafted by an expert committee on IHT constituted by the Indian Society of Critical Care Medicine. The process involved thorough review of literature from electronic database using PubMed services. Recommendations made are tailored with considerations for Indian setting; the units may further modify these as per local needs and equipment and staffing available. The final manuscript was written after achieving consensus among members, and final draft was accepted by all the committee members.</p><p><strong>Results: </strong>This position statement offers a compilation of 38 strategic recommendations, which are comprehensive and deal with all aspects of IHT of the critically ill. Recommendations provided in this document are, therefore, applicable for routine use during the IHT. They cover all phases of transport and answer questions pertaining to pre-, intra-, and post-transport considerations. It will help to achieve uniformity, minimize AEs, and enhance safety.</p><p><strong>Conclusions: </strong>This is a standard set of 38 evidence-based recommendations to ensure safety for IHT, tailored for implementation in various criticalcare settings across India. Science is ever-changing, and periodic review will be needed to keep it up to date with emerging evidence and standards.</p><p><strong>How to cite this article: </strong>Zirpe KG, Tiwari AM, Kulkarni AP, Govil D, Samavedam S, Sharma J, <i>et al</i>. Position Statement of ISCCM on Intrahospital Transport of Critically Ill Patients. Indian J Crit Care Med 2025;29(4):291-300.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"291-300"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045056/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence Risk Factors and Drug Resistance Patterns of Bacterial Isolates in Patients with Catheter-associated Urinary Tract Infections.","authors":"Tushar Jha, Mayuri Khaparde, Tejas S Parkhe, Bharat Purandare, Rutika Lavate","doi":"10.5005/jp-journals-10071-24932","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24932","url":null,"abstract":"<p><strong>Introduction: </strong>Catheter-associated urinary tract infections (CAUTIs) account for 80% of nosocomial UTIs and 40% of hospital-acquired infections, making them the most common healthcare-associated infections globally. Despite the rise of quinolone-resistant <i>Escherichia coli</i> and extended-spectrum β-lactamase-producing gram-negative bacteria, fluoroquinolones remain a common empirical treatment. Understanding antimicrobial resistance (AMR) associated with CAUTIs is critical.</p><p><strong>Methods: </strong>A prospective observational study was conducted from November 2023 to July 2024 at Deenanath Mangeshkar Hospital, Maharashtra, India. The study included catheterized patients in the intensive care unit (ICU) with a duration of over 48 hours showing UTI symptoms, including fever, suprapubic discomfort, urgency, or dysuria. Among 80 patients (mean age 56.75 ± 23.65 years; 53% male), bacterial isolates, resistance patterns, and risk factors were analyzed.</p><p><strong>Results: </strong>Catheter-associated UTIs developed in 59 patients (73.75% prevalence; 83.1 per 1,000 catheter days). Patients aged over 60, hospitalized for more than 10 days, or with comorbidities like diabetes (51.3%), hypertension (HTN) (37.5%), or chronic kidney disease (10%) were at higher risk. <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> were the most common pathogens (34.14%), with gram-negative bacilli constituting 84.74% of isolates. <i>Candida</i> species, particularly <i>C. tropicalis</i> (34.78%) and <i>C. auris</i> (26%), were also significant.</p><p><strong>Conclusion: </strong>This study identifies <i>E. coli</i>, <i>K. pneumoniae</i>, and <i>Candida</i> species as major CAUTI pathogens, with substantial multidrug resistance among gram-negative bacteria. Regular AMR surveillance and targeted infection control strategies are essential to combat CAUTI-related challenges and improve clinical outcomes.</p><p><strong>How to cite this article: </strong>Jha T, Khaparde M, Parkhe TS, Purandare B, Lavate R. Incidence Risk Factors and Drug Resistance Patterns of Bacterial Isolates in Patients with Catheter-associated Urinary Tract Infections. Indian J Crit Care Med 2025;29(4):338-344.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"338-344"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045042/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Novel \"RISC\" Score as a Risk-prediction Model of Carbapenem-resistant Hospital-acquired Infections in Adult Sepsis Patients - A Prospective Observational Study.","authors":"Abhilash B Mareguddi, Souvik Chaudhuri, Sagar M Shanmukhappa, Vishwas Parampalli, Margiben T Bhatt, Roshan Fernandes, Shwethapriya Rao, Poornima S Birajdar","doi":"10.5005/jp-journals-10071-24953","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24953","url":null,"abstract":"<p><strong>Aim and background: </strong>Antimicrobial sensitivity (AMS) reports are often available after 72 hours of identification of gram-negative (GN) hospital-acquired infection (HAI). Prediction of carbapenem-resistant infection (CRI) among GN strains is important even before AMS reports are available, for judicious use of empirical antibiotics. We aimed to study the predictors of CRI in patients with HAI.</p><p><strong>Materials and methods: </strong>We conducted a single-center prospective observational study between April 2023 and September 2024 on patients of GN sepsis with HAI. The use of empirical carbapenem antibiotics, organ dysfunction scores, the modified nutritional risk in critically ill (mNUTRIC) score, blood-count-derived inflammation indices, type of HAI, AMS reports, and in-hospital mortality were noted.</p><p><strong>Results: </strong>A total of 935 sepsis patients with HAI were screened, and there were 195 patients with GN infection. Among the 195 patients, 145 (74.4%) had CRI and 50 (25.6%) had non-CRI. Multivariable logistic regression revealed that the length of intensive care unit (ICU) stay before the day of HAI (<i>p</i> = 0.009, adjusted odds ratio (OR) 1.155, 95% confidence interval (CI) 1.037-1.286), presence of ventilator-associated pneumonia (VAP) (<i>p</i>-value < 0.001, adjusted OR 4.170, 95% CI: 1.858-9.361), empirical carbapenem antibiotics before the day of HAI (<i>p</i>-value = 0.004, adjusted OR 3.164, 95% CI: 1.439-6.957), and septic shock on the day of HAI (<i>p</i>-value 0.012, adjusted OR 4.162, 95% CI: 1.366-12.677) were the independent risk factors of CRI.</p><p><strong>Conclusion: </strong>In GN sepsis patients with HAI, respiratory infection (VAP), length of ICU stay prior to HAI, septic shock, and empirical carbapenem antibiotic administration are risk factors of CRI.</p><p><strong>How to cite this article: </strong>Mareguddi AB, Chaudhuri S, Shanmukhappa SM, Parampalli V, Bhatt MT, Fernandes R, <i>et al</i>. The Novel \"RISC\" Score as a Risk-prediction Model of Carbapenem-resistant Hospital-acquired Infections in Adult Sepsis Patients - A Prospective Observational Study. Indian J Crit Care Med 2025;29(4):352-362.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"352-362"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045060/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Hemodynamic Changes Induced by Physiotherapy in Critically Ill Patients: A Prospective Observational Study.","authors":"K J Priyanka, Dipali A Taggarsi, Bhuvana Krishna, Shiva K Narayan","doi":"10.5005/jp-journals-10071-24956","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24956","url":null,"abstract":"<p><strong>Background: </strong>The potential benefits of safe physiotherapy are immense, which may mitigate the devastating functional impairments caused by critical illness. However, there is sparse data on its safety with respect to hemodynamic changes, including the level of vasopressor therapy at which physiotherapy is deemed safe.</p><p><strong>Materials and methods: </strong>The hemodynamic parameters were recorded before, after, and every 5 minutes during physiotherapy in a total of 107 patients. Cardiac output was measured by Doppler ultrasound. Based on the type of physiotherapy, the study participants were grouped into active and passive groups. The frequencies of predefined adverse events were captured.</p><p><strong>Results: </strong>Of the 107 study participants, 65 received active physiotherapy (Group I) and 42 passive physiotherapy (Group II), with 29% on noradrenaline infusion. There was an increasing trend in each of the hemodynamic parameters after physiotherapy, as compared to rest. The mean changes in parameters before and after physiotherapy were heart rate 6.04/min; respiratory rate 3.9/min; systolic blood pressure 5 mm Hg; diastolic blood pressure 3.3 mm Hg; mean arterial pressure 3.4 mm Hg, cardiac output 0.752 L/min; and SpO₂ 0.44%. Despite being statistically significant, the small changes after physiotherapy lack clinical significance. Subgroup analysis between the active and passive physiotherapy groups was also done. The incidence of adverse events was 10.2%.</p><p><strong>Conclusion: </strong>Physiotherapy may be well tolerated in critically ill patients, even when there is a requirement for vasopressor support. Transient hemodynamic changes likely reflect physiological compensation for increased oxygen demand during physiotherapy, with low adverse event rates highlighting its safety in the intensive care unit (ICU).(CRTI Registration number: CTRI/2022/09/045766).</p><p><strong>How to cite this article: </strong>Priyanka KJ, Taggarsi DA, Krishna B, Narayan SK. Acute Hemodynamic Changes Induced by Physiotherapy in Critically Ill Patients: A Prospective Observational Study. Indian J Crit Care Med 2025;29(4):363-369.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"363-369"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045051/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Response: Can Early Use of High-flow Nasal Cannula with Improved Study Design Make a Statistically Significant Difference in the Rate of Intubation in Patients with Post-traumatic Lung Contusion?","authors":"Farouk Kamaleldeen","doi":"10.5005/jp-journals-10071-24951","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24951","url":null,"abstract":"<p><p><b>How to cite this article:</b> Kamaleldeen F. Author Response: Can Early Use of High-flow Nasal Cannula with Improved Study Design Make a Statistically Significant Difference in the Rate of Intubation in Patients with Post-traumatic Lung Contusion? Indian J Crit Care Med 2025;29(4):398-399.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"398-399"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045039/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author Response: Muscle Wasting in ICU Patients is Multifactorial and Requires thorough Workup.","authors":"Kiran Rajagopal","doi":"10.5005/jp-journals-10071-24954","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24954","url":null,"abstract":"<p><p><b>How to cite this article:</b> Rajagopal K. Author Response: Muscle Wasting in ICU Patients is Multifactorial and Requires thorough Workup. Indian J Crit Care Med 2025;29(4):395.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"395"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045043/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144006648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}