Indian Journal of Critical Care Medicine最新文献

{"title":"Role of Antimicrobial Air Purifier in Reducing the Microbial Load in the Critical Care Unit in Oncology Center: An Intervention Study.","authors":"Vijeta B Batra, Jyotirmay Kirtania, Shashank Tiwari, Priyanshu Kumar, Amit Kumar, Subarna Chakraborty","doi":"10.5005/jp-journals-10071-24910","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24910","url":null,"abstract":"<p><strong>Introduction: </strong>High quality and effective ventilation system operation plays a major role in maintaining indoor air quality in critical care unit (CCU). Aim of this study was to detect the role of antimicrobial-air-purifier in reducing the colony counts of microbes in air and high surface.</p><p><strong>Methods: </strong>This prospective study was conducted in CCU over a period of 18 months from November 2022 to May 2024 after approval from Hospital Ethics Committee. Microbial load was tested in CCU in the presence of and absence of purifier and air/high touch surface sampling was done by using settle-plate method on consecutive days in two phases (with/without purifier). Microorganism culture and identification was done using VITEK-2, and colony counting was performed using Omeliansky formula.</p><p><strong>Results: </strong>The comparison of microbial load in the CCUs between two phases revealed significant difference in the air and surface on days 1, 7, 14, 30, and 60 (<i>p</i> < 0.0001). Among gram-positive cocci (GPC), the most common isolate identified was coagulase-negative <i>Staphylococcus</i> species [35 (92.10%)], followed by <i>Micrococcus luteus</i> [5 (13.15%)] and <i>Staphylococcus aureus</i> [1 (2.63%)]. All GPC were resistant to methicillin and erythromycin while 1 (5%) strain was resistant to vancomycin, teicoplanin, and linezolid. Among gram-negative bacilli (GNB), the most common isolate was <i>Acinetobacter</i> species [8/23 (34.78%)], followed by <i>P</i>. species [5 (21.74%)]. About 19-23 (85-100%) GNB strains were resistant to third-generation cephalosporins and beta-lactam and beta-lactamase inhibitors. About 9-15 (42.3-67.64%) were resistant to tigecycline and carbapenems. Decreased bloodstream infections/catheter-associated urinary tract infections (CAUTI) rate of 3.49-2.92/3.97-1.95/1,000 patient-days was observed in CCU, while the device utilization ratio was same.</p><p><strong>Conclusion: </strong>Antimicrobial air purifier showed an effective role in decreasing the central line-associated blood stream infections and CAUTI rates in CCU.</p><p><strong>How to cite this article: </strong>Batra VB, Kirtania J, Tiwari S, Kumar P, Kumar A, Chakraborty S. Role of Antimicrobial Air Purifier in Reducing the Microbial Load in the Critical Care Unit in Oncology Center: An Intervention Study. Indian J Crit Care Med 2025;29(4):327-332.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"327-332"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Early Use of HFNC through Improved Study Design Make a Statistically Significant Difference in the Rate of Intubation in Patients with Post-traumatic Lung Contusion?","authors":"Sachit Sharma, Pramesh S Shrestha, Subhash P Acharya","doi":"10.5005/jp-journals-10071-24943","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24943","url":null,"abstract":"<p><p>Sharma S, Shrestha PS, Acharya SP. Can Early Use of HFNC through Improved Study Design Make a Statistically Significant Difference in the Rate of Intubation in Patients with Post-traumatic Lung Contusion? Indian J Crit Care Med 2025;29(4):396-397.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"396-397"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045052/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utility of Clinical Frailty Scale in Intensive Care Unit.","authors":"K M Ganesh, Bhuvana Krishna","doi":"10.5005/jp-journals-10071-24959","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24959","url":null,"abstract":"<p><p><b>How to cite this article:</b> Ganesh KM, Krishna B. Utility of Clinical Frailty Scale in Intensive Care Unit. Indian J Crit Care Med 2025;29(4):289-290.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"289-290"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045055/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Muscle Wasting in ICU Patients is Multifactorial and Requires Thorough Workup.","authors":"Josef Finsterer, Walter Strobl","doi":"10.5005/jp-journals-10071-24829","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24829","url":null,"abstract":"<p><p>Finsterer J, Strobl W. Muscle Wasting in ICU Patients is Multifactorial and Requires Thorough Workup. Indian J Crit Care Med 2025;29(4):394.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"394"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045061/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the Clinical Frailty Score on Outcomes of Critically Ill Patients in a Tertiary Care ICU.","authors":"Sulekha Saxena, Priyamvada Gupta, Puneet Panwar, Ashish Jain, Srishti S Jain, Rohit Jain, Divyansh Gupta, Munesh Meena, Hemraj Acharya, Ravi Jain","doi":"10.5005/jp-journals-10071-24949","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24949","url":null,"abstract":"<p><strong>Background: </strong>Advanced age is a known marker of vulnerability, but frailty is an independent predictor of poor outcomes in critically ill patients. The clinical frailty score (CFS) facilitates rapid assessment, aiding prognostication, care improvement, and resource allocation, particularly in resource-limited intensive care units (ICUs).</p><p><strong>Materials and methods: </strong>A prospective observational cohort study was conducted from April to September 2023 at a tertiary care ICU. The study included 166 patients aged ≥50 years with ICU stays longer than 48 hours, excluding those with contraindications for care escalation. Data were collected on demographics, Clinical parameters, and scoring systems including acute physiological and chronic health evaluation II (APACHE-II), sequential organ failure assessment (SOFA), Charlson comorbidity index (CCI), and CFS. Predictive analyses were performed using receiver operating curve (ROC) curves, cut-offs, and logistic regression.</p><p><strong>Results: </strong>The median age of patients was 65 years, with an APACHE-II score of 18 and a CFS of 4. In-hospital mortality was 46.4%. The CFS outperformed other scoring systems in predicting both in-hospital mortality [Area under the receiver operating characteristic curve (AUC-ROC) 0.73] and net negative outcomes (AUC ROC 0.75). Frailty (CFS ≥6) was present in 39.75% of patients, with each unit increase in CFS associated with a 41.8% higher odds of mortality and a 50.7% higher odds of net negative outcomes. The optimal CFS cut-offs were 4 for 80% sensitivity and 6 for 80% specificity.</p><p><strong>Conclusion: </strong>The CFS is a practical and reliable tool for predicting ICU outcomes, outperforming traditional scoring systems. It supports improved decision-making and resource allocation. Further multicenter studies are necessary to validate its broader use in critical care practice.</p><p><strong>How to cite this article: </strong>Saxena S, Gupta P, Panwar P, Jain A, Jain SS, Jain R, <i>et al</i>. Impact of the Clinical Frailty Score on Outcomes of Critically Ill Patients in a Tertiary Care ICU. Indian J Crit Care Med 2025;29(4):320-326.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"320-326"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence, Risk Factors, Microbiology and Outcomes of VAP at an NCU in India: A Prospective Observational Study.","authors":"Kapil Zirpe, Upendra Kapse, Akansha Sharma, Atul P Kulkarni, Sushma Gurav, Anand Tiwari, Chaitanya Bhujbal, Abhijeet Deshmukh, Prasad Suryawanshi, Prajakta Pote, Abhaya Bhoyar, Kaustubh Zirpe, Rupali Suryawanshi, Rahul Sharma, Piyush Dhawad, Hrishikesh Vaidya","doi":"10.5005/jp-journals-10071-24948","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24948","url":null,"abstract":"<p><strong>Background: </strong>Ventilator-associated pneumonia (VAP) remains a major challenge while managing ventilated critically ill patients in neurocritical care units (NCUs).</p><p><strong>Materials and methods: </strong>This was a prospective, single-center, observational study. All adult patients admitted to our NCU requiring mechanical ventilation (MV) for >48 hours were screened for VAP as per clinical pulmonary infectious score (CPIS) criteria. The primary outcome was the incidence of VAP in the ICU. Secondary outcomes were risk factors, microbiology, percentage of MDR/XDR organisms, mortality, and length of stay (LOS) of VAP.</p><p><strong>Results: </strong>A total of 24.94% (114 of 457) patients developed VAP. The incidence of VAP was 39.43/1000 ventilator days. Multivariate analysis of the risk factors identified, male gender, low Glasgow coma scale (GCS) of 3-8, prolonged ventilation, and diabetes mellitus as significant risk factors for the development of VAP (<i>p</i> < 0.05). <i>Acinetobacter baumannii</i> (31.58%), <i>Klebsiella pneumoniae</i> (28.95%), and <i>Pseudomonas aeruginosa</i> (13.16%) were the most common organisms responsible for VAP. Most of these isolates were multidrug resistant (MDR) (81.58%), and extensively drug-resistant (XDR) organisms (12.28%). Although VAP patients had longer ICU-LOS (26.2 ± 24.2 vs 11.8 ± 6.9 days, <i>p</i> < 0.0001), it did not affect the mortality (18.4% for VAP vs 14.3% for non-VAP, <i>p</i> = 0.5).</p><p><strong>Conclusion: </strong>Ventilator-associated pneumonia has a high incidence of 39.43 per 1,000 ventilator days in the Indian neurocritical care setting.</p><p><strong>How to cite this article: </strong>Zirpe K, Kapse U, Sharma A, Kulkarni AP, Gurav S, Tiwari A, <i>et al</i>. Incidence, Risk Factors, Microbiology and Outcomes of VAP at an NCU in India: A Prospective Observational Study. Indian J Crit Care Med 2025;29(4):308-313.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"308-313"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Risk Factors, and Clinical Outcomes of Hypervirulent <i>Klebsiella pneumoniae</i> Strains among <i>Klebsiella pneumoniae</i> Infections: A Systematic Review and Meta-analysis.","authors":"Danavath Nagendra, Souvik Chaudhuri, Nitin Gupta, Vishal Shanbhag, Vandana K Eshwara, Shwethapriya Rao, Muralidhar Varma, Thejesh Srinivas, Pratibha Todur, P S Priya, Vinutha R Bhat","doi":"10.5005/jp-journals-10071-24957","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24957","url":null,"abstract":"<p><strong>Aim and background: </strong>Hypervirulent <i>Klebsiella pneumoniae</i> (HvKp) is a virulent strain associated with invasive infections. While initially community-acquired, hospital-acquired HvKp (HA-HvKp) and carbapenem-resistant HvKp (CR-HvKp) are increasingly reported. This meta-analysis evaluates the prevalence, risk factors, and clinical outcomes associated with HvKp, including CR-HvKp and HA-HvKp, among Kp infections.</p><p><strong>Methodology: </strong>A systematic search of PubMed, Scopus, Embase, and Cochrane Library was conducted until December 2024. Observational studies comparing HvKp vs classical Kp (cKp), CR-HvKp vs carbapenem-sensitive HvKp (CS-HvKp), and HA-HvKp vs community-acquired HvKp (CA-HvKp) were included. Quality was assessed using the Joanna Briggs Critical Appraisal Tool, and pooled prevalence and odds ratios (ORs) with 95% confidence intervals (CIs) were calculated.</p><p><strong>Results: </strong>Fifty studies with 6,663 participants were included. The HvKp prevalence was 33.0%, with most studies from Asia, predominantly China. Temporal analysis revealed an increase in HvKp prevalence (27.7% in 2006-2018 to 38.5% in 2019-2024). The CR-HvKp prevalence rose from 9.5% to 16.5% (2016-2024). The HA-HvKp prevalence increased from 25.9 to 47.1%. Key risk factors included diabetes mellitus (OR = 1.56), CA-Kp (OR = 2.59), and hypermucoviscous (HM)-phenotype (OR = 29.79). Complications included liver abscess (OR = 6.35), metastatic spread (OR = 4.74), meningitis (OR = 11.14), and septic shock (OR = 1.30). Mortality was higher in HvKp infections but not statistically significant (<i>p</i> = 0.219). HA-HvKp and immunosuppression were significant CR-HvKp risk factors, with CR-HvKp showing higher mortality.</p><p><strong>Conclusions: </strong>Diabetes mellitus, CA-Kp infections, and HM-phenotype are significant risk factors for HvKp. The rising prevalence of CR-HvKp and HA-HvKp highlights the need for early detection, infection control, and targeted treatment strategies.</p><p><strong>How to cite this article: </strong>Nagendra D, Chaudhuri S, Gupta N, Shanbhag V, Eshwara VK, Rao S, <i>et al</i>. Prevalence, Risk Factors, and Clinical Outcomes of Hypervirulent <i>Klebsiella pneumoniae</i> Strains among <i>Klebsiella pneumoniae</i> Infections: A Systematic Review and Meta-analysis. Indian J Crit Care Med 2025;29(4):370-393.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"370-393"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacteremia Caused by Rare NFGNB in the ICU: A Single-center Experience.","authors":"Parikshit S Prayag, Prasad Rajhans, Nilesh Mahale, Sampada A Patwardhan, Pruthu N Dhekane, Rajeev N Soman, Deepak Sethia, Mousami Dalvi, Surabhi Dhupad, Surabhi Tyagi, Rasika S Joshi, Abhishek Deshmukh, Madhavi Wavhal, Priyamvada Sharma, Amrita P Prayag","doi":"10.5005/jp-journals-10071-24940","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-24940","url":null,"abstract":"<p><strong>Introduction: </strong>Amongst the non-fermenting gram-negative bacteria (NFGNB), <i>Pseudomonas</i> (<i>P</i>.) and <i>Acinetobacter species</i> predominate the landscape. However, less common NFGNB such as <i>Burkholderia</i>, <i>Stenotrophomonas</i>, <i>Achromobacter</i>, <i>Ralstonia</i> and <i>Elizabethkingia</i> species, amongst others, are assuming increasing importance. We describe a single-center experience of <i>bacteremia</i> caused by rare NFGNBs in an Indian intensive care unit (ICU).</p><p><strong>Materials and methods: </strong>A retrospective study of adult patients with <i>bacteremia</i> caused by rare NFGNB in the ICU.</p><p><strong>Results: </strong>Of the total 205 cases, <i>Burkholderia</i> <i>(B.)</i> species (43.4%, <i>n</i> = 89) were the commonest, followed by <i>Stenotrophomonas</i> species (20.4%, <i>n</i> = 42). The <i>bacteremia</i> was related to an indwelling catheter in 42.9 % of the patients. The median duration of hospitalization preceding the <i>bacteremia</i> was 16 days. Except for <i>B. Achromobacter</i> and <i>Aeromonas</i> <i>species</i>, meropenem showed high rates of resistance. Overall, cotrimoxazole, levofloxacin and minocycline were the most effective antibiotics active <i>in vitro;</i> with some differences noted specific to different organisms. The overall day 28 mortality was 34.1%. On multivariate analysis, the presence of shock (<i>p</i> = 0.008, CI: 1.188-5.052) and receipt of steroids (<i>p</i> = 0.015, CI: 1.032-3.891) were significantly associated with mortality.</p><p><strong>Conclusions: </strong>This is one of the largest studies from India, describing the landscape of NFGNB causing <i>bacteremia</i> in the ICU. Our study shows that these infections are acquired late during the course of hospitalization, have limited therapeutic options, and can be associated with significant mortality. Implementation of stringent infection control practices is needed to reduce this threat.</p><p><strong>How to cite this article: </strong>Prayag PS, Rajhans P, Mahale N, Patwardhan SA, Dhekane PN, Soman RN, <i>et al</i>. Bacteremia Caused by Rare NFGNB in the ICU: A Single-center Experience. Indian J Crit Care Med 2025;29(4):345-351.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 4","pages":"345-351"},"PeriodicalIF":1.5,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12045046/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143988231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Two-year Retrospective Observational Cohort Study of Benzodiazepine Overdose Cases in the Emergency Department.","authors":"John Giftson, Darpanarayan Hazra, Gina M Chandy","doi":"10.5005/jp-journals-10071-24925","DOIUrl":"10.5005/jp-journals-10071-24925","url":null,"abstract":"<p><strong>Background: </strong>Deliberate self-harm (DSH) is a significant health concern in developing countries, associated with high morbidity and mortality. Several factors influence patient outcomes. This study aimed to better understand the profile and outcomes of patients with benzodiazepine (BZD) overdose.</p><p><strong>Materials and methods: </strong>This two-year analysis conducted in the Emergency Department (ED) focused on patients with DSH and BZD toxicity. Key factors and outcomes were recorded and analyzed.</p><p><strong>Results: </strong>The study included 95 patients with BZD overdoses, some of whom had also taken other drugs. The mean age was 36.52 (SD: 14.2) years, with a female predominance (59.9%). The most common reasons for DSH were interpersonal issues, such as relationship failure (<i>n</i> = 48; 50.5%) and domestic fights or abuse (<i>n</i> = 37; 38.9%). Single-drug BZD overdose was more frequent among individuals aged 46-60 years. The predominant symptoms were drowsiness (<i>n</i> = 45; 47.4%) and nausea or vomiting (<i>n</i> = 32; 33.7%). Six patients (6.3%) required definitive airway stabilization in the ED, while two patients (2.1%) required inotropic support. Flumazenil was administered to 19 (20%) patients with no reported side effects. A majority (<i>n</i> = 49; 51.6%) of patients were admitted to the hospital, of whom 30 (61.2%) were discharged in stable condition, while 19 (38.8%) left against medical advice. No deaths were reported.</p><p><strong>Conclusion: </strong>Middle-aged females were most frequently involved in DSH cases. Single-drug BZD overdose was more common in this age-group. The predominant symptoms included drowsiness and gastrointestinal complaints. Most patients required hospital admission.</p><p><strong>How to cite this article: </strong>Giftson J, Hazra D, Chandy GM. A Two-year Retrospective Observational Cohort Study of Benzodiazepine Overdose Cases in the Emergency Department. Indian J Crit Care Med 2025;29(3):230-235.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 3","pages":"230-235"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavior of the Perme Scale and Correlation with Clinical Outcomes in the Postoperative of Coronary Artery Bypass Grafting.","authors":"André Luiz Lisboa Cordeiro, Hayssa Mascarenhas, Lucas Oliveira Soares, Vitória Pimentel, Eduarda Gomes, Larissa Pinto, Gabriel Ferreira, Luiz Alberto Forgiarini Junior, André Guimarães","doi":"10.5005/jp-journals-10071-24922","DOIUrl":"10.5005/jp-journals-10071-24922","url":null,"abstract":"<p><strong>Background: </strong>There are limiting factors that influence the assessment of mobility after cardiac surgery. Therefore, the Perme intensive care unit mobility score scale becomes more appropriate because it analyzes physical and psychological limitations in the intensive care unit (ICU), taking into account extrinsic problems.</p><p><strong>Objective: </strong>Describe the behavior of the Perme scale and its correlation with clinical outcomes in the postoperative stage of cardiac surgery.</p><p><strong>Materials and methods: </strong>This is a prospective cohort study. The patients were evaluated in four moments, to analyze the perception of pain, the degree of dyspnea, muscle strength, and functionality according to the Perme scale which ranges from 0 to 32 points. It was applied at hospital admission, ICU discharge, admission to the ward (UI), and hospital discharge. Values expressed as Delta 1 (d1) and Delta 2 (d2) were used to determine the comparison of preoperative and hospital discharge, respectively.</p><p><strong>Results: </strong>Twenty-one patients were included. Among the correlation variables at the different moments, it was perceived that cardiopulmonary bypass time d1 (<i>r</i> = 0.19; <i>p</i> = 0.42); d2 (<i>r</i> = 0.07; <i>p</i> = 0.98); ICU time d1 (<i>r</i> = 0.34; <i>p</i> = 0.17); d2 (<i>r</i> = 0.35; <i>p</i> = 0.16); hospital time d1 (<i>r</i> = 0.17; <i>p</i> = 0.54); d2 (<i>r</i> = 0.21; <i>p</i> = 0.47) and mechanical ventilation (MV) time d1 (<i>r</i> = 0.09; <i>p</i> = 0.70); d2 (<i>r</i> = 0.44; <i>p</i> = 0.06) showed no statistically significant difference. The variables hospital admission (31 ± 1) and ICU discharge (20 ± 4) showed significant losses in the length of stay in these units.</p><p><strong>Conclusion: </strong>The evaluation performed with the Perme scale showed significance when comparing the values between ICU admission and discharge. However, in relation to the clinical outcomes of this study, no relevant correlations were proven.</p><p><strong>How to cite this article: </strong>Cordeiro ALL, Mascarenhas H, Soares LO, Pimentel V, Gomes E, Pinto L, <i>et al</i>. Behavior of the Perme Scale and Correlation with Clinical Outcomes in the Postoperative of Coronary Artery Bypass Grafting. Indian J Crit Care Med 2025;29(3):273-277.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 3","pages":"273-277"},"PeriodicalIF":1.5,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11915388/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}