{"title":"The Quality and Significance of a Study on the Validity of the CAM-ICU Depends Heavily on their Inclusion and Exclusion Criteria.","authors":"Josef Finsterer","doi":"10.5005/jp-journals-10071-24923","DOIUrl":"10.5005/jp-journals-10071-24923","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"472-473"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"High-dose Vitamin D may Have No Effect on Mortality in Vitamin D-deficient Pediatric ICU Patients because the Study Design is Inappropriate.","authors":"Fulvio A Scorza, Carla A Scorza, Josef Finsterer","doi":"10.5005/jp-journals-10071-24942","DOIUrl":"10.5005/jp-journals-10071-24942","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"468-469"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Serum Uric Acid in Sepsis: A Hidden Prognostic Clue or Just Another Red Herring?","authors":"Sahil Kataria, Deven Juneja, Prashant Nasa","doi":"10.5005/jp-journals-10071-24975","DOIUrl":"10.5005/jp-journals-10071-24975","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"402-403"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Author Response: The Quality and Significance of a Study on the Validity of the CAM-ICU Depends Heavily on their Inclusion and Exclusion Criteria.","authors":"Rashmi Salhotra, Abhirup Bose","doi":"10.5005/jp-journals-10071-24967","DOIUrl":"10.5005/jp-journals-10071-24967","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"474-475"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101989/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vetriselvan Parasuraman, Rahul K Anand, Puneet Khanna, Rakupathy Shanmugam, Bikash Ranjan Ray
{"title":"Effect of High Protein Normocaloric Nutrition on Skeletal Muscle Wasting in Critically Ill Mechanically Ventilated Patients: A Randomized Double-blind Study.","authors":"Vetriselvan Parasuraman, Rahul K Anand, Puneet Khanna, Rakupathy Shanmugam, Bikash Ranjan Ray","doi":"10.5005/jp-journals-10071-24966","DOIUrl":"10.5005/jp-journals-10071-24966","url":null,"abstract":"<p><strong>Background and aims: </strong>Muscle wasting in critically ill patients is associated with poor outcomes. During intensive care unit (ICU) stay, delivering appropriate nutritional support helps minimize muscle loss. We sought to evaluate the impact of high-dose protein on muscle thickness and cross-sectional area (CSA), as well as to track changes in muscle echogenicity and pennation angle (PA) using bedside ultrasound in this population.</p><p><strong>Patients and methods: </strong>We conducted a randomized, prospective, double-blind trial in which 30 patients mechanically ventilated for more than 48 hours and receiving enteral feed were enrolled. Patients were divided into two groups, and all patients received enteral feeds with total calories of about 25 kcal/kg/day. In the high-protein feed (HPF) group, patients were targeted to receive 1.5 gm/kg/day of protein, whereas in the standard feed (SF) group, patients received 1 gm/kg/day of protein. After ICU admission, muscle thickness, CSA, echogenicity, and PA were measured in all mechanically ventilated patients on days 1, 3, 5, and 7 using bedside ultrasound. The right lower limb vastus lateralis (VL) and the medial head of the gastrocnemius were investigated.</p><p><strong>Results: </strong>We found a progressive decrease in muscle mass from day 1 to day 7 in all patients. Our study showed that muscle thickness and CSA were significantly higher in the HPF group than the SF group over 7 days, whereas muscle echogenicity and PA changes were not statistically significant.</p><p><strong>Conclusion: </strong>High-protein feeds prevent muscle wasting in critically ill patients compared to patients receiving SFs during the first week of ICU stay. The qualitative muscle parameters, like muscle echogenicity and PA changes, were not significant.</p><p><strong>How to cite this article: </strong>Parasuraman V, Anand RK, Khanna P, Shanmugam R, Ray BK. Effect of High Protein Normocaloric Nutrition on Skeletal Muscle Wasting in Critically Ill Mechanically Ventilated Patients: A Randomized Double-blind Study. Indian J Crit Care Med 2025;29(5):431-440.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"431-440"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101975/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Md Parwaj H Ansari, Nidhi Arun, Anand Dev, Ankita Verma
{"title":"Accidental Endotracheal Tube Displacement in Intensive Care Unit Patients: A Randomized Comparison of Three Different Endotracheal Tube-securing Tapes.","authors":"Md Parwaj H Ansari, Nidhi Arun, Anand Dev, Ankita Verma","doi":"10.5005/jp-journals-10071-24960","DOIUrl":"10.5005/jp-journals-10071-24960","url":null,"abstract":"<p><strong>Background and aims: </strong>Several materials and techniques are used for securing the endotracheal tube (ETT). This randomized, controlled trial was conducted to compare three different types of fixation tapes: (1) Cloth-based, nonadhesive, nonelastic tape (gauze tape); (2) Silk-based, adhesive, nonelastic tape (Durapore™); and (3) Cloth-based, adhesive, elastic tape (Dynaplast™), with the primary objective to compare the incidence of displacement (≥1 cm) of ETT in intensive care unit (ICU) patients.</p><p><strong>Patients and methods: </strong>This randomized prospective comparative trial was conducted on 150 ICU patients, of either gender between 16 and 80 years of age requiring endotracheal intubations. All patients were randomly allocated into groups A, B, and C. Endotracheal tube was secured with gauze tape, Durapore™, and Dynaplast™ in groups A, B, and C, respectively, with uniform technique. The final insertion depth of the ETT was marked, and displacement ≥ 1 cm was recorded. Ease of fixation, time taken, need for assistance, adhesive quality, and skin changes were also recorded and compared.</p><p><strong>Results: </strong>Endotracheal tube displacement ≥ 1 cm over 24 hours was recorded in 58.7, 35.4, and 29.8% of patients in tape gauze, Durapore™, and Dynaplast™, respectively (<i>χ</i> <sup>2</sup> = 11.372, <i>p</i> = 0.011). Durapore™ and Dynaplast™ were quicker and easier to apply, but with a high incidence of skin complications.</p><p><strong>Conclusion: </strong>Although no single material emerged superior in all aspects, our findings highlight the trade-offs between ease of application, risk of skin complications, and fixation security. The ideal fixation material may vary depending on patient characteristics, clinical context, and institutional resources.</p><p><strong>How to cite this article: </strong>Md Ansari PH, Arun N, Dev A, Verma A. Accidental Endotracheal Tube Displacement in Intensive Care Unit Patients: A Randomized Comparison of Three Different Endotracheal Tube-securing Tapes. Indian J Crit Care Med 2025;29(5):418-423.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"418-423"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Author Response: Postoperative Recovery from a Cardiac Anesthesiologists' Perspective.","authors":"André L Cordeiro, Luiz A Forgiarini","doi":"10.5005/jp-journals-10071-24963","DOIUrl":"10.5005/jp-journals-10071-24963","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"467"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gauri Kumar, Muralidhar Varma, Chiranjay Mukhopadhyay, Vandana K Eshwara
{"title":"Is Enterococcal Bacteremia a Cause or Corollary of Severe Illness? 5 Years' Experience from an Indian Teaching Hospital.","authors":"Gauri Kumar, Muralidhar Varma, Chiranjay Mukhopadhyay, Vandana K Eshwara","doi":"10.5005/jp-journals-10071-24969","DOIUrl":"10.5005/jp-journals-10071-24969","url":null,"abstract":"<p><strong>Background and aims: </strong>Enterococci have emerged as successful pathogens in healthcare-associated infections due to their hardiness and survival ability in environments with high background antimicrobial pressure. Enterococcal bacteremia (EB) present an intriguing link between the host, environmental and healthcare practices. We present here the detailed clinical epidemiology of EB from an Indian hospital.</p><p><strong>Patients and methods: </strong>We retrospectively studied adult patients diagnosed with bacteremia by Enterococcal species for 5 years. The details of clinical characteristics, implicated species, factors contributing to the development of bacteremia and the underlying source were analyzed. All the clinical and laboratory findings and antimicrobial therapy associated with clinical outcome were assessed.</p><p><strong>Results: </strong><i>Enterococcus faecium</i> was the predominant pathogen in 82(42.5%) of the total 193 cases. Prior healthcare exposure was evident in 136(70.46%). Direct admission to intensive care during initial presentation was noted in 107(55.4%) of study cohort. Among 82(42.5%) of EB, source could be identified and central line infection was the commonest source in 45(23.3%). In-hospital mortality was 47, 23%, while 40(21%) left the hospital due to poor clinical outcome. Multivariate analysis indicated age >60 years, intra-abdominal disease as initial presentation, staying in the ICU during bacteremia, presence of central line and invasive mechanical ventilation as independent risk factors for fatality and poor clinical outcome.</p><p><strong>Conclusion: </strong>Enterococcal bacteremia can present both as cause and outcome of severe illness. Multiple comorbidities, healthcare acquisition, and limited therapy options suggest the need for strategies to prevent the invasive infections by enterococci.</p><p><strong>How to cite this article: </strong>Kumar G, Varma M, Mukhopadhyay C, Eshwara VK. Is Enterococcal Bacteremia a Cause or Corollary of Severe Illness? 5 Years' Experience from an Indian Teaching Hospital. Indian J Crit Care Med 2025;29(5):441-448.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"441-448"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Author Response: High-dose Vitamin D may Have No Effect on Mortality in Vitamin D-deficient Pediatric ICU Patients because the Study Design is Inappropriate.","authors":"Mrityunjay Sakkarwal, Pallavi Pallavi, Urmila Jhamb, Romit Saxena","doi":"10.5005/jp-journals-10071-24964","DOIUrl":"10.5005/jp-journals-10071-24964","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"470-471"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimizing the Treatment of Critically Ill Patients Utilizing Beta-D-glucan: The Time is Now.","authors":"Anjali Shetty","doi":"10.5005/jp-journals-10071-24974","DOIUrl":"10.5005/jp-journals-10071-24974","url":null,"abstract":"","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"29 5","pages":"404-406"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12101972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}