Indian Journal of Critical Care Medicine最新文献

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C-reactive Protein-to-albumin Ratio (CAR) in Polytrauma-Early Warning or Marker of Disease Evolution? c反应蛋白与白蛋白比(CAR)是多伤早期预警还是疾病演变的标志?
IF 1.5
Indian Journal of Critical Care Medicine Pub Date : 2026-02-01 Epub Date: 2026-02-13 DOI: 10.5005/jp-journals-10071-25138
Khushboo Saran, Bodhisatwa Choudhuri, Shio Priye, Jay Prakash
{"title":"C-reactive Protein-to-albumin Ratio (CAR) in Polytrauma-Early Warning or Marker of Disease Evolution?","authors":"Khushboo Saran, Bodhisatwa Choudhuri, Shio Priye, Jay Prakash","doi":"10.5005/jp-journals-10071-25138","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-25138","url":null,"abstract":"<p><p><b>How to cite this article:</b> Saran K, Choudhuri B, Priye S, Prakash J. C-reactive Protein-to-albumin Ratio (CAR) in Polytrauma-Early Warning or Marker of Disease Evolution? Indian J Crit Care Med 2026;30(2):182-183.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"30 2","pages":"182-183"},"PeriodicalIF":1.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Response: Letter in Response to the Article: Utility of Extracellular Nicotinamide Phosphoribosyl Transferase as a Novel Biomarker in Predicting Early Severe Organ Dysfunction and Mortality in Acute Respiratory Distress Syndrome: A Prospective Observational Study. 细胞外烟酰胺磷酸核糖转移酶作为预测急性呼吸窘迫综合征早期严重器官功能障碍和死亡率的新型生物标志物的应用:一项前瞻性观察研究。
IF 1.5
Indian Journal of Critical Care Medicine Pub Date : 2026-02-01 Epub Date: 2026-02-13 DOI: 10.5005/jp-journals-10071-25151
Shwethapriya Rao, Souvik Chaudhuri
{"title":"Author Response: Letter in Response to the Article: Utility of Extracellular Nicotinamide Phosphoribosyl Transferase as a Novel Biomarker in Predicting Early Severe Organ Dysfunction and Mortality in Acute Respiratory Distress Syndrome: A Prospective Observational Study.","authors":"Shwethapriya Rao, Souvik Chaudhuri","doi":"10.5005/jp-journals-10071-25151","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-25151","url":null,"abstract":"<p><p><b>How to cite this article:</b> Rao S, Chaudhuri S. Author Response: Letter in Response to the Article: Utility of Extracellular Nicotinamide Phosphoribosyl Transferase as a Novel Biomarker in Predicting Early Severe Organ Dysfunction and Mortality in Acute Respiratory Distress Syndrome: A Prospective Observational Study. Indian J Crit Care Med 2026;30(2):175-176.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"30 2","pages":"175-176"},"PeriodicalIF":1.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Hand Massage on Pain, Anxiety, and Comfort Levels of Intensive Care Patients: A Randomized Controlled Trial. 手部按摩对重症病人疼痛、焦虑和舒适度的影响:一项随机对照试验。
IF 1.5
Indian Journal of Critical Care Medicine Pub Date : 2026-02-01 Epub Date: 2026-02-13 DOI: 10.5005/jp-journals-10071-25129
Havva Sert, Busra Gurcay, Ferhat Koc, Merve Gulbahar Eren, Bilgehan A Acar, Yagmur Toprak
{"title":"The Effect of Hand Massage on Pain, Anxiety, and Comfort Levels of Intensive Care Patients: A Randomized Controlled Trial.","authors":"Havva Sert, Busra Gurcay, Ferhat Koc, Merve Gulbahar Eren, Bilgehan A Acar, Yagmur Toprak","doi":"10.5005/jp-journals-10071-25129","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-25129","url":null,"abstract":"<p><strong>Background and aims: </strong>Hand massage is a nonpharmacological nursing intervention that reduces pain, anxiety, and discomfort. This study aimed to evaluate the effects of hand massage on pain, anxiety, and comfort levels in neurological intensive care unit (ICU) patients, contributing to evidence-based nursing practice.</p><p><strong>Patients and methods: </strong>This randomized controlled trial was conducted in a neurology ICU in Turkey. A total of 66 patients were randomly assigned to intervention and control groups. The intervention group received 12 hand massage sessions over six consecutive days (twice daily). Pain, anxiety, and comfort were assessed using the visual analog scale (VAS), the Spielberger state-trait anxiety inventory (STAI), and the general comfort scale-short form (GCS-SF). The control group received standard care. Data were analyzed using one-way ANOVA, the Kruskal-Wallis <i>H</i> test, and the Bonferroni <i>post-hoc</i> analysis.</p><p><strong>Results: </strong>Patients in the intervention group demonstrated significantly reduced pain and anxiety levels and increased comfort at both 15 and 60 minutes postintervention compared with the control group (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>Hand massage based on Kolcaba's comfort theory is a safe, low-cost, and effective intervention that reduces pain and anxiety while enhancing comfort in neurological ICU patients. Integrating hand massage into routine care may support holistic symptom management in critical care settings.</p><p><strong>How to cite this article: </strong>Sert H, Gurcay B, Koc F, Eren MG, Acar BA, Toprak Y. The Effect of Hand Massage on Pain, Anxiety, and Comfort Levels of Intensive Care Patients: A Randomized Controlled Trial. Indian J Crit Care Med 2026;30(2):140-147.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"30 2","pages":"140-147"},"PeriodicalIF":1.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999703/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual Harassment in Intensive Care Unit Settings. 重症监护病房环境中的性骚扰。
IF 1.5
Indian Journal of Critical Care Medicine Pub Date : 2026-02-01 Epub Date: 2026-02-13 DOI: 10.5005/jp-journals-10071-25139
Prakash Gondode, Christopher Dass, Ram Singh, Puneet Khanna
{"title":"Sexual Harassment in Intensive Care Unit Settings.","authors":"Prakash Gondode, Christopher Dass, Ram Singh, Puneet Khanna","doi":"10.5005/jp-journals-10071-25139","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-25139","url":null,"abstract":"<p><strong>Background and aims: </strong>Sexual harassment in intensive care units (ICUs) is a critical yet underreported issue affecting staff and patients alike. This review examines the prevalence, typologies, risk factors, legal frameworks, and barriers to reporting within ICU environments.</p><p><strong>Data sources: </strong>Peer-reviewed literature from PubMed, Scopus, and Google Scholar, along with verified media reports and legal documents, were reviewed.</p><p><strong>Study selection: </strong>Included sources focused on ICU-specific sexual harassment involving healthcare workers and patients. Studies and sources addressing legal responses, institutional mechanisms, and vulnerable populations were prioritized.</p><p><strong>Data synthesis: </strong>Intensive care unit harassment stems from peers, superiors, patients, and attendants, manifesting across verbal, physical, and digital forms. Female, LGBTQ+ (Lesbian, Gay, Bisexual, Transgender, and Queer+), and junior staff, as well as sedated patients, face heightened risk. Barriers to reporting include fear of retaliation, cultural stigma, and ineffective institutional redressal. Legal mandates like India's POSH Act remain poorly enforced.</p><p><strong>Conclusion: </strong>Harassment in ICUs threatens staff safety and patient dignity. Addressing it demands ICU-specific policy, trauma-informed reporting systems, and cultural change toward accountability and protection.</p><p><strong>How to cite this article: </strong>Gondode P, Dass C, Singh R, Khanna P. Sexual Harassment in Intensive Care Unit Settings. Indian J Crit Care Med 2026;30(2):165-172.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"30 2","pages":"165-172"},"PeriodicalIF":1.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Accuracy of Point-of-care Ultrasonography for Confirming Endotracheal Tube Placement in Adults: An Updated Systematic Review and Meta-analysis. 成人气管插管置放的即时超声诊断准确性:最新的系统回顾和荟萃分析。
IF 1.5
Indian Journal of Critical Care Medicine Pub Date : 2026-02-01 Epub Date: 2026-02-13 DOI: 10.5005/jp-journals-10071-25152
Mohammed Alsabri, Ahmed B Elsnhory, Mohammed T Hasan, Christopher H McClean, Khaled Abouelmagd, Eslam Abady, Abdelrahman M Tawfik, Michael Lajeunesse, Amira A Aboali, Patrick Yoo, Aysha Hasan
{"title":"Diagnostic Accuracy of Point-of-care Ultrasonography for Confirming Endotracheal Tube Placement in Adults: An Updated Systematic Review and Meta-analysis.","authors":"Mohammed Alsabri, Ahmed B Elsnhory, Mohammed T Hasan, Christopher H McClean, Khaled Abouelmagd, Eslam Abady, Abdelrahman M Tawfik, Michael Lajeunesse, Amira A Aboali, Patrick Yoo, Aysha Hasan","doi":"10.5005/jp-journals-10071-25152","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-25152","url":null,"abstract":"<p><strong>Background: </strong>Point-of-care ultrasonography (POCUS) is increasingly used to confirm endotracheal tube (ETT) placement; however, its overall diagnostic accuracy and speed compared with standard methods in adult emergency and critical care settings remain uncertain.</p><p><strong>Methods: </strong>We conducted a systematic review and meta-analysis of observational studies through May 2025 that evaluated POCUS for confirming ETT placement in adults (≥18 years) in emergency departments (EDs) and intensive care units (ICUs).</p><p><strong>Results: </strong>Thirty studies met the inclusion criteria. Point-of-care ultrasonography achieved a pooled sensitivity of 0.91 and a specificity of 0.98. The area under the curve (AUC) was 0.96 [95% confidence interval (CI): 0.88-1.00]. The mean time-to-confirmation was 19.62 seconds for POCUS vs 22.46 seconds for standard methods; however, this finding should be interpreted with caution due to extreme heterogeneity (<i>I</i>² > 99%).</p><p><strong>Conclusion: </strong>Point-of-care ultrasonography is a highly accurate, rapid, and reliable method for confirming ETT placement in adult ED and ICU settings. It demonstrates diagnostic performance comparable to previously reported capnography performance and provides unique advantages as an adjunctive tool, especially in scenarios where capnography may be unreliable.</p><p><strong>How to cite this article: </strong>Alsabri M, Elsnhory AB, Hasan MT, McClean CH, Abouelmagd K, Abady E, <i>et al</i>. Diagnostic Accuracy of Point-of-care Ultrasonography for Confirming Endotracheal Tube Placement in Adults: An Updated Systematic Review and Meta-analysis. Indian J Crit Care Med 2026;30(2):155-164.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"30 2","pages":"155-164"},"PeriodicalIF":1.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
C-reactive Protein/Albumin Ratio in Septic Polytrauma: Predictive Marker or Concurrent Indicator? c反应蛋白/白蛋白比率在脓毒性多发伤中:预测指标还是并发指标?
IF 1.5
Indian Journal of Critical Care Medicine Pub Date : 2026-02-01 Epub Date: 2026-02-13 DOI: 10.5005/jp-journals-10071-25137
Chinmaya K Panda, Habib Mr Karim
{"title":"C-reactive Protein/Albumin Ratio in Septic Polytrauma: Predictive Marker or Concurrent Indicator?","authors":"Chinmaya K Panda, Habib Mr Karim","doi":"10.5005/jp-journals-10071-25137","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-25137","url":null,"abstract":"<p><p><b>How to cite this article:</b> Panda CK, Karim HMR. C-reactive Protein/Albumin Ratio in Septic Polytrauma: Predictive Marker or Concurrent Indicator? Indian J Crit Care Med 2026;30(2):181.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"30 2","pages":"181"},"PeriodicalIF":1.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and Psychometric Validation of the Intensive Care Unit Caregiver Distress Scale. 重症监护室照顾者痛苦量表的编制与心理计量学验证。
IF 1.5
Indian Journal of Critical Care Medicine Pub Date : 2026-02-01 Epub Date: 2026-02-13 DOI: 10.5005/jp-journals-10071-25117
Usha Chivukula, Kirtideepa Subhadarsani
{"title":"Development and Psychometric Validation of the Intensive Care Unit Caregiver Distress Scale.","authors":"Usha Chivukula, Kirtideepa Subhadarsani","doi":"10.5005/jp-journals-10071-25117","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-25117","url":null,"abstract":"<p><strong>Background and aims: </strong>Family caregivers of intensive care unit (ICU) patients experience significant psychological distress; however, existing general caregiver measurement instruments fail to capture the unique stressors inherent to intensive care settings. This study aimed to develop a self-report instrument to measure psychological distress specific to ICU family caregivers, explore its core dimensional structure, and evaluate its psychometric properties.</p><p><strong>Patients and methods: </strong>The ICU Caregiver Distress Scale (ICU-CDS) was developed and validated in multiple phases, including item generation, content validation, and pilot testing. A sample of 313 family caregivers of ICU patients participated in the study. Exploratory and confirmatory factor analyses were conducted to identify and confirm the scale's dimensional structure and psychometric properties.</p><p><strong>Results: </strong>The ICU-CDS demonstrated a clear multidimensional structure with a Cronbach's <i>α</i> coefficient of 0.72. Additionally, the scale showed satisfactory convergent validity through positive correlations with the Mishel Uncertainty in Illness Scale.</p><p><strong>Conclusion: </strong>The ICU-CDS provides a robust, contextually sensitive measure of psychological distress among ICU family caregivers. By capturing specific stressors unique to the ICU setting, this scale addresses critical limitations of existing general caregiver instruments and can be utilized to assess distress among ICU patient family caregivers.</p><p><strong>How to cite this article: </strong>Chivukula U, Subhadarsani K. Development and Psychometric Validation of the Intensive Care Unit Caregiver Distress Scale. Indian J Crit Care Med 2026;30(2):128-133.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"30 2","pages":"128-133"},"PeriodicalIF":1.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Point-of-care Ultrasonography for Endotracheal Tube Confirmation: An Essential Adjunct in Airway Management. 即时超声检查用于气管插管确认:气道管理的重要辅助手段。
IF 1.5
Indian Journal of Critical Care Medicine Pub Date : 2026-02-01 Epub Date: 2026-02-13 DOI: 10.5005/jp-journals-10071-25156
Neeraj Kumar
{"title":"Point-of-care Ultrasonography for Endotracheal Tube Confirmation: An Essential Adjunct in Airway Management.","authors":"Neeraj Kumar","doi":"10.5005/jp-journals-10071-25156","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-25156","url":null,"abstract":"<p><p><b>How to cite this article:</b> Kumar N. Point-of-care Ultrasonography for Endotracheal Tube Confirmation: An Essential Adjunct in Airway Management. Indian J Crit Care Med 2026;30(2):92-94.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"30 2","pages":"92-94"},"PeriodicalIF":1.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999692/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Paraquat Poisoning: When Intensive Care Meets the Limits of Medicine. 百草枯中毒:当重症监护遇到医学极限。
IF 1.5
Indian Journal of Critical Care Medicine Pub Date : 2026-02-01 Epub Date: 2026-02-13 DOI: 10.5005/jp-journals-10071-25155
Ashok K Pannu, Ashish Bhalla
{"title":"Paraquat Poisoning: When Intensive Care Meets the Limits of Medicine.","authors":"Ashok K Pannu, Ashish Bhalla","doi":"10.5005/jp-journals-10071-25155","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-25155","url":null,"abstract":"<p><p><b>How to cite this article:</b> Pannu AK, Bhalla A. Paraquat Poisoning: When Intensive Care Meets the Limits of Medicine. Indian J Crit Care Med 2026;30(2):88-89.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"30 2","pages":"88-89"},"PeriodicalIF":1.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Temporal Analysis of Diastolic Shock Index in Patients with Septic Shock and Its Correlation with Clinical Outcomes in an Indian Setting: A Prospective Observational Study. 印度脓毒性休克患者舒张期休克指数的时间分析及其与临床结果的相关性:一项前瞻性观察研究
IF 1.5
Indian Journal of Critical Care Medicine Pub Date : 2026-02-01 Epub Date: 2026-02-13 DOI: 10.5005/jp-journals-10071-25130
Soumya Sarkar, Ashish K Sharma, Afzal Azim, Jitendra S Chahar, Sangam Yadav, Pv Sai Saran, Prabhakar Mishra, Mohan Gurjar, Banani Poddar
{"title":"Temporal Analysis of Diastolic Shock Index in Patients with Septic Shock and Its Correlation with Clinical Outcomes in an Indian Setting: A Prospective Observational Study.","authors":"Soumya Sarkar, Ashish K Sharma, Afzal Azim, Jitendra S Chahar, Sangam Yadav, Pv Sai Saran, Prabhakar Mishra, Mohan Gurjar, Banani Poddar","doi":"10.5005/jp-journals-10071-25130","DOIUrl":"https://doi.org/10.5005/jp-journals-10071-25130","url":null,"abstract":"<p><strong>Background: </strong>Diastolic shock index (DSI), the ratio of heart rate to diastolic arterial pressure, reflects vascular tone and sympathetic drive in septic shock. While baseline DSI correlates with mortality, its temporal evolution remains exploratory.</p><p><strong>Patients and methods: </strong>In this single-center prospective observational study, adult patients with septic shock (as per sepsis-3) were enrolled. Diastolic shock index, shock index (SI), and modified shock index (MSI) were recorded at 0, 6, 12, and 24 hours. Delta diastolic shock index (ΔDSI), lactate clearance, and vasoactive-inotropic score (VIS) were analyzed using repeated-measures ANOVA, receiver operating characteristic (ROC) analysis, Cox regression, and multivariable logistic regression (SPSS v23, MedCalc).</p><p><strong>Results: </strong>Of 157 patients screened, 90 were included. Median age was 40 years (male 64.4%) with median SOFA and APACHE II scores of 9 and 18, respectively. Nonsurvivors had higher lactate (24 mg/dL, <i>p</i> < 0.001) and lower platelet counts. Overall, 28-day mortality was 37.8%. Declining DSI, MSI, and SI over 24 hours were seen in the survivor group. Delta diastolic shock index correlated inversely with lactate clearance (<i>r</i> = -0.40, <i>p</i> < 0.01) and vasopressor-free days (<i>r</i> = -0.33, <i>p</i> = 0.001). Receiver operating characteristic analysis showed that ΔDSI (AUC = 0.684) outperformed baseline DSI (AUC = 0.402). A combined model (ΔDSI + VIS_0 + Lactate_0) improved discrimination (AUC = 0.781). In logistic regression, ΔDSI (OR 4.07, <i>p</i> = 0.006), Lactate_0 (OR 1.04, <i>p</i> = 0.012), and APACHE II (OR 1.14, <i>p</i> = 0.002) independently predicted mortality.</p><p><strong>Conclusion: </strong>Temporal improvement in DSI (ΔDSI) independently predicts ICU mortality and correlates with vascular recovery. Integrating ΔDSI with VIS and lactate enhances risk stratification in septic shock.</p><p><strong>How to cite this article: </strong>Sarkar S, Sharma AK, Azim A, Chahar JS, Yadav S, Sai Saran PV, <i>et al</i>. Temporal Analysis of Diastolic Shock Index in Patients with Septic Shock and Its Correlation with Clinical Outcomes in an Indian Setting: A Prospective Observational Study. Indian J Crit Care Med 2026;30(2):99-106.</p>","PeriodicalId":47664,"journal":{"name":"Indian Journal of Critical Care Medicine","volume":"30 2","pages":"99-106"},"PeriodicalIF":1.5,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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