Journal of Addictive Diseases最新文献_第4页

Levels of vitamin D and a bone resorption marker in the sera of young women with alcohol use disorder. 患有酒精使用障碍的年轻女性血清中维生素D和骨吸收标志物的水平。

IF 1.6 4区医学

Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-11-11 DOI: 10.1080/10550887.2023.2264999

Kayo Masuko, Chie Iwahara, Shigemi Kamiya, Seiji Sakate, Yuki Mizukami

{"title":"Levels of vitamin D and a bone resorption marker in the sera of young women with alcohol use disorder.","authors":"Kayo Masuko, Chie Iwahara, Shigemi Kamiya, Seiji Sakate, Yuki Mizukami","doi":"10.1080/10550887.2023.2264999","DOIUrl":"10.1080/10550887.2023.2264999","url":null,"abstract":"Background: Excessive alcohol drinking negatively affects bone metabolism and leads to a risk of decreased bone mass, which is a major component of the pathogenesis of osteoporosis. However, the potential influence of alcohol on bones has not been fully recognized, particularly among the young to middle-aged generation.Objectives: This study aimed to investigate the status of serum markers related to bone metabolism in young to middle-aged women with alcohol use disorder (AUD).Methods: Levels of vitamin D and the bone-resorption marker tartrate-resistant acid phosphatase 5b were measured in the sera of 25 women with AUD (mean age, 39.5 ± 7.5 years) who were enrolled in an AUD rehabilitation program. Data of samples obtained on admission and those after eight weeks were compared.Results: Of the 25 women with AUD, 19 (76%) had vitamin D deficiency (<20 ng/mL), and most of the patients showed relatively higher tartrate-resistant acid phosphatase 5b levels at baseline considering their premenopausal age. Although the levels did not change significantly at week eight of the AUD rehabilitation program, vitamin D levels tended to increase initially in patients with vitamin D deficiency. Although further investigations and detailed nutritional assessment are necessary, the results of this study may support the presence of a relatively unknown influence of AUD on the bone health of the young to middle-aged population. Along with psychological and physical care, persons with AUD should be treated as a high-risk group for future osteoporosis regardless of age.","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"447-455"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72211326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex differences in variables affecting short-term success in substance use disorder treatment. 影响药物使用障碍治疗短期成功的变量的性别差异。

IF 1.6 4区医学

Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-08-25 DOI: 10.1080/10550887.2023.2247949

Kishan Desai, Vivian Hagerty, Varun Hariharan, Monica Perdomo, Elie Levy, Deepak Berwal, Ximena Levy, Julie Pilitsis

{"title":"Sex differences in variables affecting short-term success in substance use disorder treatment.","authors":"Kishan Desai, Vivian Hagerty, Varun Hariharan, Monica Perdomo, Elie Levy, Deepak Berwal, Ximena Levy, Julie Pilitsis","doi":"10.1080/10550887.2023.2247949","DOIUrl":"10.1080/10550887.2023.2247949","url":null,"abstract":"Because of the stigma surrounding patients with substance use disorder (SUD) and difficulties with follow-up, data on outcomes is limited. We explore real-world data from a prospectively collected database to determine characteristics that contribute to the completion of acute treatment. Our cohort consisted of data from 1039 patients treated at a single facility. Success was defined as successful discharge from the program. Failure was defined as relapse or signing out against medical advice during treatment. We examined 43 distinct features collected at time of treatment using multivariate analysis. In the total cohort and both sexes, longer length of stay (p ≤ 0.01) was linked to treatment failure. When we examined the cohort by sex, variables associated with success and failure differed between groups. Among females, goal-directed thinking (p ≤ 0.05) correlated with treatment success. Taking unnecessary risks (p < 0.05), having a detailed suicide plan (p ≤ 0.001), and constricted thinking (p ≤ 0.01) predicted treatment failure. In males, prior arrest for driving under the influence (p ≤ 0.05), and presence of phobias, paranoias, and delusions (p ≤ 0.05) were associated with treatment failure. Identifying patients prone to acute therapy failure may guide more personalized treatment, thereby increasing success rates. When considering SUD treatments for patients, we must stratify based on patient characteristics.","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"400-409"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10063012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of psilocybin use in vaping and associated factors: a study among amphetamine-type stimulants (ATS) use disorder in Malaysia. 在吸食中使用迷幻药的流行率及相关因素：一项关于马来西亚苯丙胺类兴奋剂（ATS）使用障碍的研究。

IF 1.6 4区医学

Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-08-04 DOI: 10.1080/10550887.2023.2240932

Ruzmayuddin Mamat, Rusdi Abd Rashid, Sim Maw Shin, Baharudin Ibrahim, Suzaily Wahab, Azmir Ahmad

{"title":"Prevalence of psilocybin use in vaping and associated factors: a study among amphetamine-type stimulants (ATS) use disorder in Malaysia.","authors":"Ruzmayuddin Mamat, Rusdi Abd Rashid, Sim Maw Shin, Baharudin Ibrahim, Suzaily Wahab, Azmir Ahmad","doi":"10.1080/10550887.2023.2240932","DOIUrl":"10.1080/10550887.2023.2240932","url":null,"abstract":"Background: The emergence of New Psychoactive Substances (NPS), including synthetic psilocybin, has raised concern among health experts due to the numerous health and socioeconomic consequences. The current trend is shifting to the hazardous use of synthetic psilocybin in vaping, and little is known about the prevalence of use, specifically among amphetamine-type stimulants (ATS) users.Methods: Interviewer-administered questionnaires were conducted in drug detention centers between March and October 2022. The study was conducted using ASSIST 3.0 and obtained information on the respondents' socio-demographic characteristics and clinical profiles. N = 355 ATS users were enrolled in this study.Results: The results show a high prevalence of psilocybin vaping among ATS users (182/355, 53.1%). Most of the respondents were males (85.1%) and unmarried (69.3%), with a mean age of 29.2 (SD = 7.3). Across all respondents, five factors were associated with psilocybin vaping: tobacco smoking, aOR =5.790 (95% CI: 1.723, 8.183); cannabis uses, aOR= 9.152 (95% CI: 2.693, 10.396); and alcohol use, aOR= 3.137 (95% CI: 1.461, 5.817). Respondents of the Malay race had higher odds of being involved in psilocybin vaping compared to other races, with aOR= 1.638 (0.043, 2.459). Meanwhile, a reduction in age by 1.9 will increase the likelihood of involvement in psilocybin vaping with aOR = 1.897 (95% CI: 0.857, 1.938).Conclusion: Psilocybin in vaping is growing among ATS users and across all populations. Unfortunately, knowledge regarding the long-term effects on health is limited. Further studies should highlight the harmful effects of psilocybin and the potential risk of psilocybin vaping among the younger population.","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"360-372"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10318899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kratom use and mental health: A systematic literature review and case example. Kratom的使用与心理健康：系统的文献综述和案例分析。

IF 1.6 4区医学

Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-11-09 DOI: 10.1080/10550887.2023.2273192

Anil K Bachu, Prakamya Singal, Brittany Griffin, Lauren Harbaugh, Sakshi Prasad, Lakshit Jain, Syed Mohiuddin, Bhavani Nagendra Papudesi, Tarika Nagi, Nagy A Youssef, Amit Chopra, Saeed Ahmed

{"title":"Kratom use and mental health: A systematic literature review and case example.","authors":"Anil K Bachu, Prakamya Singal, Brittany Griffin, Lauren Harbaugh, Sakshi Prasad, Lakshit Jain, Syed Mohiuddin, Bhavani Nagendra Papudesi, Tarika Nagi, Nagy A Youssef, Amit Chopra, Saeed Ahmed","doi":"10.1080/10550887.2023.2273192","DOIUrl":"10.1080/10550887.2023.2273192","url":null,"abstract":"Objective: This review aims to synthesize and critically evaluate the existing literature on kratom use and its possible association with induction of psychotic and manic symptoms, in order to identify potential areas for future research that would improve our understanding of the risks of kratom consumption.Methods: An electronic search was performed using five major databases: including PubMed, Scopus, Google Scholar, Web of Science, and PsycINFO. keywords such as kratom, Mitragyna speciosa, mania, psychosis, bipolar disorder, schizophrenia, schizoaffective, case report, and case series. The retrieved articles on initial search were screened based on predefined inclusion and exclusion criteria for this study, and then data synthesis was performed to analyze relevant information from the included studies.Results: Six prior papers were found using (1 case series and 5 case reports). These included 10 cases, involving kratom use association with mania and psychosis. The ages of patients ranged from 28 to 55 years mean age was 38, and (SD 13.74), the majority were males (8 out of 11). Patients had durations of kratom use ranging from 2 wk to 15 years. Significant association was found between kratom use and the worsening of psychotic and manic symptoms in individuals with psychiatric conditions.Conclusions: Our research highlights the possibility of worsening preexisting psychiatric conditions in the context of kratom use. This study emphasizes the need for clinical evaluation of patients for kratom use. Additional research is required to gain a deeper understanding of the potential mental health implications of kratom use, especially among vulnerable populations.","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"301-312"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71522962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Operationalizing person-centered care in residential substance use disorder treatment. 在住院药物使用障碍治疗中落实以人为本的护理。

IF 1.6 4区医学

Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-08-21 DOI: 10.1080/10550887.2023.2247810

Barbara Andraka-Christou, Olivia K Golan, Rachel Totaram, Morgan C Shields, Kendall Cortelyou, Danielle N Atkins, Glenn W Lambie, Olena Mazurenko

{"title":"Operationalizing person-centered care in residential substance use disorder treatment.","authors":"Barbara Andraka-Christou, Olivia K Golan, Rachel Totaram, Morgan C Shields, Kendall Cortelyou, Danielle N Atkins, Glenn W Lambie, Olena Mazurenko","doi":"10.1080/10550887.2023.2247810","DOIUrl":"10.1080/10550887.2023.2247810","url":null,"abstract":"Introduction: Person-centered care (PCC) is an ethical imperative with eight domains, but operation of some PCC domains in substance use disorder (SUD) treatment has been underexplored.Objective: We sought to identify strategies for operationalizing eight PCC domains in SUD treatment facilities and themes across these strategies.Methods: We recruited 36 clients and staff from a large publicly funded behavioral health system for individual, semi-structured qualitative interviews. Interviews explored preferences and care experiences for each PCC domain. We analyzed data using iterative categorization, identifying specific operationalization strategies and themes across operationalization strategies within each domain.Results: PCC operationalization themes for residential SUD treatment included addressing social vulnerability of clients (e.g., through assistance with housing and navigation of criminal/legal systems), involving peer support specialists (e.g., to provide emotional support and aid transition out of care), supporting the client's family throughout treatment (e.g., providing progress updates; increasing visitation opportunities in residential treatment), and facilitating patient choice within each domain (e.g., treatment type; housing type; roommate preferences in residential treatment.).Discussion & conclusion: Some PCC operationalization strategies are unique to SUD treatment. Several PCC operationalization strategies applied to multiple domains, suggesting conceptual overlap between domains.","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"384-399"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10388224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barriers to seeking treatment for alcohol use disorders among males in a tertiary care center in South India - a cross-sectional study. 南印度一家三级医疗中心男性寻求酒精使用障碍治疗的障碍——一项横断面研究。

IF 1.6 4区医学

Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-10-13 DOI: 10.1080/10550887.2023.2265804

Mathew Veena, Johnson-Pradeep Ruben, Nisha Chacko Kunjumon, Harshad Devarbhavi

{"title":"Barriers to seeking treatment for alcohol use disorders among males in a tertiary care center in South India - a cross-sectional study.","authors":"Mathew Veena, Johnson-Pradeep Ruben, Nisha Chacko Kunjumon, Harshad Devarbhavi","doi":"10.1080/10550887.2023.2265804","DOIUrl":"10.1080/10550887.2023.2265804","url":null,"abstract":"Background: There are limited studies on barriers to seeking treatment for Alcohol Use Disorders (AUD) among males in tertiary care centers in India and abroad. Identification of these factors can aid in addressing the barriers to seeking treatment for AUD in low-and-middle-income countries.Objective: To investigate the barriers to seeking treatment for AUD among males in a tertiary care center in South India.Methods: The study design was cross-sectional. We employed a semi-structured interview proforma, Barriers Questionnaire (Alcohol), and assessed the age of onset of initiation of alcohol, problem drinking, and AUD.Results: The majority (73.3%) belonged to Low-Barrier group. Individual items such as \"Denial of Alcoholism\", \"avoid others counseling\", \"don't like to talk in groups\", \"Worried about what others will think for taking help or made fun of by others\", \"Self or Family embarrassed of taking treatment\", \"cannot afford treatment due to various reasons\", \"Fear of losing job\", \"Fear of losing friends\" and \"Fear of seeing people\" were significantly higher in High-Barrier group.Conclusions: Our study has helped to identify some of the important impediments. Psychoeducation and reducing the stereotypes related to the treatment of AUD can increase trust in the treatment process, resulting in greater help-seeking, early intervention, and improved quality of life.","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"456-463"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41216057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison between cytisine and Nicotine Replacement Therapy in smoking cessation among inpatient psychiatric patients. 比较胞二磷胆碱和尼古丁替代疗法在精神病住院患者中的戒烟效果。

IF 1.6 4区医学

Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-08-11 DOI: 10.1080/10550887.2023.2237395

Maria Tavakoli-Ardakani, Zeinab Gholamzadeh Sani, Narges Beyraghi, Shadi Najarimoghadam, Ali Kheradmand

{"title":"Comparison between cytisine and Nicotine Replacement Therapy in smoking cessation among inpatient psychiatric patients.","authors":"Maria Tavakoli-Ardakani, Zeinab Gholamzadeh Sani, Narges Beyraghi, Shadi Najarimoghadam, Ali Kheradmand","doi":"10.1080/10550887.2023.2237395","DOIUrl":"10.1080/10550887.2023.2237395","url":null,"abstract":"Introduction: Smoking is more common among people with mental disorders and is associated with adverse effects. Some compounds, including nicotine and cytisine, have been used in many individuals to increase success in smoking cessation. In this study, the effect of cytisine on the smoking status of patients hospitalized in the psychiatry department was investigated.Method: Forty-seven patients, hospitalized in the psychiatry ward, motivated to quit smoking, participated in this open-label randomized trial. Thirty patients used nicotine gums 2 mg (Nicolife®) for eight weeks, and the remaining took cytisine pills (Tabex®) according to the manufacturer's instructions for 25 days. All patients were followed up for six months. The primary outcome was smoking cessation, measured by the mood and physical symptoms scale (MPSS), the AUDIT alcohol consumption questions (AUDIT-C), confirmatory factor analyses, and reliability of the modified cigarette evaluation questionnaire at the end of the 1st week and at 1st, 2nd and 6th months after quit day.Findings: Only two out of 30 patients (6.66%) in the group taking Nicotine Replacement Therapy (NRT) could quit smoking entirely (no cigarettes after six months). In contrast, three out of 17 patients (17.64%) managed to do so in the cytisine group. The number of cigarettes smoked by the patients in both groups decreased, but the reduction was significant in the cytisine group.Conclusion: Cytisine is an effective and suitable agent for smoking cessation in patients with psychological problems, with fewer adverse effects and more success rate compared to NRT.","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"352-359"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9974389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction. 更正。

IF 1.6 4区医学

Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-08-18 DOI: 10.1080/10550887.2023.2243084

引用次数: 0

Suicidal ideations and self-dehumanization in recently detoxified patients with severe alcohol use disorder: an experimental exploration through joint explicit-implicit measures. 新近戒毒的严重酒精使用障碍患者的自杀意念和自我非人化：通过显性和隐性联合测量法进行的实验探索。

IF 1.6 4区医学

Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-12-19 DOI: 10.1080/10550887.2023.2292303

Sullivan Fontesse, Tina Chevallereau, Florence Stinglhamber, Stéphanie Demoulin, Anna Fiorito, Armand Chatard, Nemat Jaafari, Pierre Maurage

{"title":"Suicidal ideations and self-dehumanization in recently detoxified patients with severe alcohol use disorder: an experimental exploration through joint explicit-implicit measures.","authors":"Sullivan Fontesse, Tina Chevallereau, Florence Stinglhamber, Stéphanie Demoulin, Anna Fiorito, Armand Chatard, Nemat Jaafari, Pierre Maurage","doi":"10.1080/10550887.2023.2292303","DOIUrl":"10.1080/10550887.2023.2292303","url":null,"abstract":"Background: Metadehumanization (the feeling of being considered as less than human by others) is a pervasive phenomenon in psychiatric states, notably promoting self-dehumanization and suicide antecedents. However, its role in suicidal ideations among patients with addictive disorders remains unexplored. We thus investigated the involvement of metadehumanization/self-dehumanization in suicidal ideations and suicidal thoughts interference in severe alcohol use disorder.Methods: We measured metadehumanization, suicidal ideations, and desire for social contact through questionnaires among 35 recently detoxified patients with severe alcohol use disorder (26 males). We measured animalistic/mechanistic self-dehumanization using an Implicit Association Task, and suicidal thoughts interference using a Stroop Task with suicide-related words. We performed regression analyses while controlling for depression/anxiety.Results: Animalistic self-dehumanization was positively associated with suicidal thoughts interference and with decreased desire for social interactions, such link being absent for metadehumanization or mechanistic self-dehumanization.Conclusions: This link between self-dehumanization and suicide-related factors suggests that a reduced sense of belonging to humanity is associated with self-harm antecedents. Results also emphasize the importance of using indirect measures to investigate sensitive variables, such as self-dehumanization and suicidal thoughts.","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"500-507"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138808697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Buprenorphine: two adolescent case reports of bridging the transmucosal form to the extended-release subcutaneous injectable form. 丁丙诺啡：两例青少年经口服剂型与缓释皮下注射剂型衔接的病例报告。

IF 1.6 4区医学

Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2024-01-25 DOI: 10.1080/10550887.2023.2251366

Vivek Velagapudi, Luke Schuster, Roopa Sethi

{"title":"Buprenorphine: two adolescent case reports of bridging the transmucosal form to the extended-release subcutaneous injectable form.","authors":"Vivek Velagapudi, Luke Schuster, Roopa Sethi","doi":"10.1080/10550887.2023.2251366","DOIUrl":"10.1080/10550887.2023.2251366","url":null,"abstract":"According to the Centers for Disease Control and Prevention (CDC), 100,306 drug overdose deaths occurred in the US during a 12-month period ending in April 2021. Opioids were involved in 75% of these related deaths. Opioid Use Disorder (OUD) is a constantly evolving public health crisis with potentially lethal consequences. In 2017, 900 adolescents began to misuse opioids every day. Nearly 10% of high school seniors reported using opioids nonmedically. Additionally, the incidence for hospitalizations for adolescents among children 1-19 years of age increased nearly 2-fold from 1997 to 2012. This data emphasizes the dangers associated with the increasing accessibility of pharmaceutical and non-pharmaceutical opioids, particularly for adolescents. All three of the currently FDA approved medications for OUD have shown clear efficacy in decreasing all-cause mortality in adults. It is proposed that the same effects should be seen in adolescents but limited data is present. A recent study analyzed buprenorphine and naltrexone treatment amongst OUD in adolescents between 2001-2014; only 1 in 4 youth received any medication therapy within six months of diagnosis. Adolescents under 16 were the most likely to receive medications. However, even adolescents aged 17, for whom buprenorphine is FDA approved for, were less likely to receive therapy than adults over 18 years of age. The following case report aims to demonstrate how subcutaneous extended release buprenorphine treatment can be initiated effectively as an outpatient in an adolescent with OUD. It is critical that clinicians work to expand access to pharmacotherapy for adolescents struggling with OUD to ensure proper management and reduction of opioid-related overdoses.","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"426-431"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139547238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0