Journal of Addictive Diseases最新文献

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Trends in maternal opioid use: Statewide differences by sociodemographic characteristics in Florida from 2000 to 2019. 产妇使用阿片类药物的趋势:2000 年至 2019 年佛罗里达州按社会人口特征划分的全州差异。
IF 1.6 4区 医学
Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2024-02-18 DOI: 10.1080/10550887.2024.2302285
Amanda L Elmore, Nansi S Boghossian, Alexander C McLain, Suzanne McDermott, Jason L Salemi
{"title":"Trends in maternal opioid use: Statewide differences by sociodemographic characteristics in Florida from 2000 to 2019.","authors":"Amanda L Elmore, Nansi S Boghossian, Alexander C McLain, Suzanne McDermott, Jason L Salemi","doi":"10.1080/10550887.2024.2302285","DOIUrl":"10.1080/10550887.2024.2302285","url":null,"abstract":"<p><strong>Background: </strong>Maternal opioid use (MOU) remains a public health concern. Studies have demonstrated significant increases in MOU, but estimates using ICD-10-CM or stratified by sociodemographic variables are limited.</p><p><strong>Objectives: </strong>Using a statewide, population-based dataset of Florida resident deliveries from 2000 to 2019, we examined the trend of MOU by age, race/ethnicity, education level, and insurance.</p><p><strong>Methods: </strong>Florida administrative data was used to conduct a retrospective cohort study. MOU was identified using opioid-related hospital discharge diagnoses documented prenatally or at delivery. Maternal sociodemographic variables were obtained from Florida vital statistics. Joinpoint regression was used to identify statistically significant changes in the trends overall and stratified by sociodemographic variables. Results are presented as annual percentage changes (APC) and 95% confidence intervals.</p><p><strong>Results: </strong>Our sample included over 3.6 million Florida resident mothers; of which, MOU was identified in 1% (<i>n</i> = 22,828) of the sample. From 2000 to 2019, MOU increased over ten-fold from 8.7 to 94.7 per 10,000 live birth deliveries. MOU increased significantly from 2000 to 2011 (APC: 32.8; 95% CI: 29.4, 36.2), remained stable from 2011 to 2016, and decreased significantly from 2016 to 2019 (APC: 3.9; 95% CI: -6.6, -1.0). However, from 2016 to 2019, MOU increased among non-Hispanic Black mothers (APC: 9.2; 95% CI: 7.5, 11.0), and those ages 30-34 (APC: 2.9; 95% CI: 1.2, 4.6) and 35-39 (APC: 6.4; 95% CI: 4.3, 8.4).</p><p><strong>Conclusions: </strong>Accurate prevalence estimates of MOU by sociodemographic factors are necessary to fully understand prevalence trends, describe the burden among sub-populations, and develop targeted interventions.</p>","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"524-534"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11330537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139900707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Co-occurring pain and addiction: prognostic implications for healthcare professionals in residential treatment for substance use disorder. 疼痛与成瘾并发症:对住院治疗药物使用障碍的医护人员的预后影响。
IF 1.6 4区 医学
Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-06-28 DOI: 10.1080/10550887.2023.2223505
Apollonia E Lysandrou, Scott A Teitelbaum, Lisa Merlo, Ben Phalin, Amanda Janner, Laurie Solomon, Jason Hunt, Ben Lewis
{"title":"Co-occurring pain and addiction: prognostic implications for healthcare professionals in residential treatment for substance use disorder.","authors":"Apollonia E Lysandrou, Scott A Teitelbaum, Lisa Merlo, Ben Phalin, Amanda Janner, Laurie Solomon, Jason Hunt, Ben Lewis","doi":"10.1080/10550887.2023.2223505","DOIUrl":"10.1080/10550887.2023.2223505","url":null,"abstract":"<p><p><b><i>Objectives</i></b>: Chronic pain is both an important antecedent and consequence of substance use. Although evidence suggests healthcare professionals may be uniquely vulnerable to chronic pain, this vulnerability remains largely unexamined in the context of recovery from substance use disorders (SUDs). We characterized pain in a sample of treatment-seeking individuals, examined potential differences in pain trajectories between healthcare professionals and non-healthcare patients, and interrogated potential pain-related vulnerabilities in treatment outcomes between these groups. <b><i>Methods</i></b>: Patients with SUDs (<i>n</i> = 663; 251 women) completed questionnaires indexing pain intensity, craving, and abstinence self-efficacy (including self-efficacy in pain-related contexts). Assessments were conducted at treatment entry, 30 days, and discharge. Analyses included chi-square and longitudinal mixed models. <b><i>Results</i></b>: The proportion of healthcare and non-healthcare patients endorsing recent pain was equivalent (χ<sup>2</sup>=1.78, <i>p=.</i>18). Healthcare professionals reported lower pain intensity (<i>p</i> = 0.02) and higher abstinence self-efficacy (<i>p</i> < 0.001). Profession by pain interactions (<i>p</i>s <.040) revealed that among medical professionals, associations between pain and all three treatment outcomes of interest were more robust relative to the non-healthcare group. <b><i>Conclusions</i></b>: Results suggest that although healthcare professionals endorse similar rates of pain and lower average pain intensity, they may be uniquely vulnerable to pain-related disruptions in craving and abstinence self-efficacy.</p>","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"335-344"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9694695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Causal inference in tobacco research: a public health challenge. 烟草研究中的因果推论:公共卫生挑战。
IF 1.6 4区 医学
Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-08-31 DOI: 10.1080/10550887.2023.2252305
Mohammad Ebrahimi Kalan, Kenneth D Ward, Paul T Harrell, Ziyad Ben Taleb
{"title":"Causal inference in tobacco research: a public health challenge.","authors":"Mohammad Ebrahimi Kalan, Kenneth D Ward, Paul T Harrell, Ziyad Ben Taleb","doi":"10.1080/10550887.2023.2252305","DOIUrl":"10.1080/10550887.2023.2252305","url":null,"abstract":"<p><p>Causal inference represents a rapidly expanding interdisciplinary subfield that involves various assumptions, study designs, and estimation strategies, allowing researchers to establish causal relationships from both clinical trials and observational data. In tobacco research, numerous studies address causal questions, including the contentious issue of whether vaping in nonsmoking youth leads to smoking initiation, known as the \"gateway effect.\" Determining the effectiveness and safety of many health interventions will continue to rely on observational [mainly longitudinal] data because randomized trials are not always feasible, ethical, or timely. Therefore, review articles that are synthesizing evidence on the gateway effects of electronic nicotine delivery systems [ENDS] on subsequent cigarette smoking must also consider observational studies as first-rate evidence that can help bring together the polarized tobacco research community and help better understand the \"gateway effect.\" In addition, this will help ongoing efforts to rigorously prevent ENDS use by youth while expanding the cessation potential of ENDS among adult established smokers who are unwilling to quit otherwise. In this commentary, we discuss causal inference tobacco research as one of the public health challenges and provide some recommendations/implications.</p>","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"582-585"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10177514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterizing safer drinking strategies among hospitalized adults with severe alcohol use disorder; a cross-sectional secondary analysis. 在患有严重酒精使用障碍的住院成人中描述更安全的饮酒策略;横断面二次分析。
IF 1.6 4区 医学
Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-11-09 DOI: 10.1080/10550887.2023.2275555
Jennifer Lyden, Ryan Loh, Hannan Braun, Dale Terasaki
{"title":"Characterizing safer drinking strategies among hospitalized adults with severe alcohol use disorder; a cross-sectional secondary analysis.","authors":"Jennifer Lyden, Ryan Loh, Hannan Braun, Dale Terasaki","doi":"10.1080/10550887.2023.2275555","DOIUrl":"10.1080/10550887.2023.2275555","url":null,"abstract":"<p><strong>Background: </strong>Safer drinking strategies (SDS) reduce alcohol-related harms in outpatient settings. Little is known about SDS among hospitalized patients.</p><p><strong>Objective: </strong>Evaluate SDS among hospitalized patients with alcohol use disorder (AUD) and assess for association with past-year acute-care utilization.</p><p><strong>Methods: </strong>We conducted a cross-sectional, secondary analysis of hospitalized adults with AUD at a safety-net hospital in Colorado from January-December 2021. Participants completed a questionnaire on SDS and were categorized as low (≤2 reported) or high SDS (≥3 reported). Past-year emergency department visits and hospital admissions were identified using the electronic health record. A Mann-Whitney test compared encounters between low and high SDS groups.</p><p><strong>Results: </strong>Among 43 hospitalized adults with AUD, 38 (88.4%) reported ≥1 SDS and 21 (48.8%) reported ≥3 SDS. The low SDS group had fewer past-year admissions than the high SDS group (<i>U</i> = 145.0, <i>p</i> = 0.015).</p><p><strong>Conclusion: </strong>SDS are frequently identified by patients and may be an acceptable form of inpatient AUD management.</p>","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"551-555"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72015708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of depression and smoking cessation: outcomes of an 18-year retrospective cohort study. 抑郁症与戒烟的关系:一项18年回顾性队列研究的结果。
IF 1.6 4区 医学
Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-10-18 DOI: 10.1080/10550887.2023.2270369
Haruyuki Kawai, Jun Kondo, Kenji Kuwaki, Maiko Hayashibara, Aguri Nakamura, Naoko Sato, Mari Fujii, Mihoko Kato, Tomomi Ohara, Naomi Wakimoto, Mika Honiden, Shinji Takata
{"title":"Association of depression and smoking cessation: outcomes of an 18-year retrospective cohort study.","authors":"Haruyuki Kawai, Jun Kondo, Kenji Kuwaki, Maiko Hayashibara, Aguri Nakamura, Naoko Sato, Mari Fujii, Mihoko Kato, Tomomi Ohara, Naomi Wakimoto, Mika Honiden, Shinji Takata","doi":"10.1080/10550887.2023.2270369","DOIUrl":"10.1080/10550887.2023.2270369","url":null,"abstract":"<p><strong>Background: </strong>Depression is frequently associated with unsuccessful smoking cessation.</p><p><strong>Objective: </strong>In this study, we investigated the impact of depression history on smoking cessation success in a clinical setting.</p><p><strong>Methods: </strong>This retrospective study included 726 patients who visited our smoking cessation clinic between January 1, 2001, and December 31, 2018. Kaplan-Meier analyses and Cox proportional hazards regression models were used to perform univariate and multivariate analyses of smoking cessation success factors.</p><p><strong>Results: </strong>Among the 726 patients, 76 had a history of depression and demonstrated significantly lower 12-week quit rate compared to those without (33.6% vs. 69.6%, <i>p</i> < .001). Multivariate Cox analysis revealed a significant association between abstinence rate and history of depression (hazard ratio 2.251, 95% CI 1.505-3.315, <i>p</i> < .001), history of schizophrenia (hazard ratio 2.716, 95% CI 1.427-4.840, <i>p</i> = .003), and Fagerström Nicotine Dependence Test scores (hazard ratio 1.519, 95% CI 1.053-2.197, <i>p</i> = .025).</p><p><strong>Conclusions: </strong>Our findings suggested that a history of depression is a significant prognostic factor for smoking cessation, underscoring the need for targeted interventions for patients with a history of depression. The findings of this study are subject to potential selection bias due to recruitment from a single hospital, which may limit the generalizability of our results. This study highlights the necessity for novel, specialized smoking cessation therapies to support patients with a history of depression in their cessation journey.</p>","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"472-480"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic factors linked to aberrant neural activity of individuals with substance use disorder phenotypes: A systematic review and meta-analysis of EEG studies. 与药物使用障碍表型个体异常神经活动有关的遗传因素:脑电图研究的系统回顾和荟萃分析。
IF 1.6 4区 医学
Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-07-09 DOI: 10.1080/10550887.2023.2232252
Marco Cavicchioli, Andrea Galbiati, Valentina Tobia, Anna Ogliari
{"title":"Genetic factors linked to aberrant neural activity of individuals with substance use disorder phenotypes: A systematic review and meta-analysis of EEG studies.","authors":"Marco Cavicchioli, Andrea Galbiati, Valentina Tobia, Anna Ogliari","doi":"10.1080/10550887.2023.2232252","DOIUrl":"10.1080/10550887.2023.2232252","url":null,"abstract":"<p><strong>Background: </strong>Alterations in EEG activity have been considered valid endophenotypes of substance use disorders (SUDs). Empirical evidence has supported the association between genetic factors (e.g., genes, single nucleotide polymorphisms [SNPs]) and SUDs, considering both clinical samples and individuals with a positive family history of SUDs [F<sup>+</sup>SUD]). Nevertheless, the relationship between genetic factors and intermediate phenotypes (i.e., altered EEG activity) among individuals with SUD phenotypes remains unclear.</p><p><strong>Objective(s): </strong>The current study aims at summarizing genetic factors linked to aberrant EEG activity among individuals with SUDs and those with F<sup>+</sup>SUD.</p><p><strong>Methods: </strong>Sixteen studies (5 [<i>N</i> = 986] + 11 from the <i>Collaborative Studies On Genetics of Alcoholism</i> [COGA] sample [432 ≤ <i>N</i> ≤ 8810]) were included for a qualitative systematic review. Thirteen studies (5 + 8 studies from the COGA sample) were used for multi-level meta-analytic procedures.</p><p><strong>Results: </strong>Qualitative analyses highlighted a multivariate genetic architecture linked to alterations in EEG waves among individuals with SUD phenotypes (i.e., augmented resting-state beta waves; reduced resting-state alpha waves; reduced resting-state and task-dependent theta waves). The most recurrent genetic factors were involved in cellular energy homeostasis, modulation of inhibitory and excitatory neural activity together with neural cell growth. Meta-analytic results showed a moderate association between genetic factors and altered resting-state and task-dependent EEG activity. Meta-analytic results also suggested non-additive genetic effects on altered EEG activity.</p><p><strong>Conclusions: </strong>Complex genetic interactions mediating neural activity and brain development might constitute a causal pathway toward intermediate phenotypes associated with phenotypic features, which in turn are linked to SUDs.</p>","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"289-300"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9761057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Substance use disorders after natural disasters: a narrative review. 自然灾害后的药物使用失调:叙述性综述。
IF 1.6 4区 医学
Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-07-30 DOI: 10.1080/10550887.2023.2242073
Gamze Zengin İspir, Mustafa Danışman, Kübra Sezer Katar
{"title":"Substance use disorders after natural disasters: a narrative review.","authors":"Gamze Zengin İspir, Mustafa Danışman, Kübra Sezer Katar","doi":"10.1080/10550887.2023.2242073","DOIUrl":"10.1080/10550887.2023.2242073","url":null,"abstract":"<p><p>Natural disasters significantly impact individuals and communities, including damage to infrastructure, injuries, loss of life, and psychological distress. Factors contributing to the development of substance use disorders (SUDs) during and after these events include trauma and stress, disruption of social support networks, availability of substances, and lack of access to mental health services. This paper aims to draw attention to the relationship between SUDs and natural disasters. Thus, we reviewed the literature by following SANRA guidelines. Prevention and intervention strategies to reduce the risk of SUDs during and after natural disasters are providing mental health services, strengthening social support networks, limiting access to substances, and providing education and training to healthcare providers, emergency responders, and community members. Considering the mental health needs of individuals affected by natural disasters is essential to mitigate the risk of SUDs and other mental health conditions.</p>","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"578-581"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9952342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors related to opioid misuse among patients undergoing elective surgery in Poland. 波兰择期手术患者中阿片类药物滥用的相关因素。
IF 1.6 4区 医学
Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-09-30 DOI: 10.1080/10550887.2023.2252721
Jakub Klimkiewicz, Maria Wysocka, Martyna Hordowicz, Jerzy Jarosz, Mateusz Gutowski, Kamil Paryż, Anna Kieszkowska-Grudny, Anna Klimkiewicz
{"title":"Factors related to opioid misuse among patients undergoing elective surgery in Poland.","authors":"Jakub Klimkiewicz, Maria Wysocka, Martyna Hordowicz, Jerzy Jarosz, Mateusz Gutowski, Kamil Paryż, Anna Kieszkowska-Grudny, Anna Klimkiewicz","doi":"10.1080/10550887.2023.2252721","DOIUrl":"10.1080/10550887.2023.2252721","url":null,"abstract":"<p><p>In many countries, the consumption of illicit opioids is rising, becoming a major public health issue called the \"opioid crisis\". Many reasons contribute to this phenomenon. One of them is opioid misuse, defined as the use of legally prescribed opioids for a purpose different than pain treatment. This matter has not been well studied in Poland, where the opioid crisis has not been identified so far. This study was conducted among patients admitted for elective surgery with opioid-based postoperative pain treatment. The frequency of opioid misuse was found to be 10.8% in a sample comprising 92 patients. The group of individuals with potential opioid use disorder had a more frequent history of inadequately controlled postoperative pain compared to the group of non-misusers (<i>p</i> = 0.023). Furthermore, this group asked to receive additional pain treatment almost six times more often than the control group (<i>p</i> < 0.000). Also, patients declaring opioid misuse reported substantial differences concerning their knowledge and opinions about pain treatment and opioid analgesics: supporting the administration of opioids for pain when needed, finding opioids less harmful, and supporting messages that opioids are safe, effective, well-tolerated, easy to cutoff more often than control. There is an urgent need for the education of patients to avoid the spreading of the opioid crisis.</p>","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"438-446"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41148668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
President's message. 主席致辞
IF 1.6 4区 医学
Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2024-08-23 DOI: 10.1080/10550887.2024.2393024
Jon Lepley
{"title":"President's message.","authors":"Jon Lepley","doi":"10.1080/10550887.2024.2393024","DOIUrl":"10.1080/10550887.2024.2393024","url":null,"abstract":"","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"271-273"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiovascular health in kratom users; a narrative review. kratom使用者的心血管健康状况;叙述性评论
IF 1.6 4区 医学
Journal of Addictive Diseases Pub Date : 2024-10-01 Epub Date: 2023-11-20 DOI: 10.1080/10550887.2023.2282033
Fatemeh Chichagi, Reyhaneh Alikhani, Asghar Beigi Harchegani
{"title":"Cardiovascular health in kratom users; a narrative review.","authors":"Fatemeh Chichagi, Reyhaneh Alikhani, Asghar Beigi Harchegani","doi":"10.1080/10550887.2023.2282033","DOIUrl":"10.1080/10550887.2023.2282033","url":null,"abstract":"<p><strong>Background: </strong>Kratom, also known as Mitragyna speciosa, is a plant that originates in Southeast Asia and possesses unique pharmacological characteristics. It is commonly consumed in the form of tea made by boiling the leaves or using the leaves to create the powder. According to its pain-relieving effects, the prevalence of kratom use around the world has increased, which has various implications for healthcare providers. Mitragynine is a well-known active compound in kratom.</p><p><strong>Objective: </strong>This review aims to provide a comprehensive perspective on the cardiovascular effects of mitragynine and its potential cardiotoxicity through the literature.</p><p><strong>Method: </strong>Authors searched PubMed, Scopus, and Google Scholar databases using appropriate search strategies for each database. After the screening, all relevant studies were included.</p><p><strong>Results: </strong>Although kratom may have the potential for therapeutic benefits, it has been associated with multi-organ damage and cardiac toxicity in some cases. According to the available data, tachycardia and hypertension are the most common adverse effects. Other possible cardiovascular effects include atherosclerosis, ventricular arrhythmia, cardiomyopathy, dose-dependent prolonged QTc interval, myocarditis, cardiomegaly, and cardiopulmonary arrest.</p><p><strong>Conclusion: </strong>While prior research has indicated the possible negative effects of mitragynine overdose on the cardiovascular system, there are no definitive conclusions, and additional investigations are needed.</p>","PeriodicalId":47493,"journal":{"name":"Journal of Addictive Diseases","volume":" ","pages":"313-325"},"PeriodicalIF":1.6,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138048188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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