Polish Journal of Radiology最新文献

{"title":"Efficacy of the endovascular ovarian vein embolization technique in pelvic venous congestion syndrome.","authors":"Sinan Sozutok,&nbsp;Ferhat Can Piskin,&nbsp;Huseyin Tugsan Balli,&nbsp;Hasan Bilen Onan,&nbsp;Omer Kaya,&nbsp;Erol Huseyin Aksungur","doi":"10.5114/pjr.2022.119807","DOIUrl":"https://doi.org/10.5114/pjr.2022.119807","url":null,"abstract":"<p><strong>Purpose: </strong>Pelvic pain, either related or unrelated to menstruation, is especially common in women of reproductive age. Thirty-nine per cent of all women suffer from chronic pelvic pain at some point in their lives, and pelvic venous congestion syndrome (PVCS) is the cause of this pain in 30% of cases. The aim of this study was to determine factors affecting the success of endovascular venous embolization used in the treatment of PVCS, and to present the long-term treatment results.</p><p><strong>Material and methods: </strong>The data of 144 female patients who underwent endovascular ovarian vein embolization for PVCS between January 2012 and July 2020 were retrospectively analysed.</p><p><strong>Results: </strong>Pain management was determined to be very successful in 37 (25.6%) patients, successful in 55 (38.1%), and unsuccessful in 52 (35.3%). Treatments using a coil alone were significantly more successful in pain management than those involving the use of different materials in addition to the coil (<i>p</i> = 0.036). In addition, patients with unilateral insufficiency before the procedure were found to have more successful pain management than those with bilateral insufficiency (<i>p</i> = 0.041). Reproductive/postmenopausal state and parity did not have a statistically significant effect on treatment efficacy (<i>p</i> = 0.250 and <i>p</i> = 0.573, respectively).</p><p><strong>Conclusions: </strong>Endovascular pelvic venous embolization is an important option in the treatment of PVCS due its less invasive and reproducible nature.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/44/fe/PJR-87-47889.PMC9536205.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33516880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prevalence of isolated tentorial hypoplasia on magnetic resonance imaging.","authors":"Özkan Ünal,&nbsp;Halil İbrahim Şara","doi":"10.5114/pjr.2022.119483","DOIUrl":"https://doi.org/10.5114/pjr.2022.119483","url":null,"abstract":"<p><strong>Purpose: </strong>The tent shape of the tentorium cerebelli helps preserve brain anatomy by providing cerebellum protection against pressure caused by the brain's gravity effect. In the absence of this support structure of the tentorium, herniation occurs in the brain. Isolated tentorial hypoplasia (TH) is extremely rare. In this study, we aimed to calculate the prevalence of this entity, which is reported to be rare in the literature.</p><p><strong>Material and methods: </strong>Magnetic resonance imaging (MRI) images of 5163 patients who applied to the training and research hospital for various reasons between 1 September 2020, and 31 August 2021, who underwent brain MRI, were reviewed retrospectively.</p><p><strong>Results: </strong>The prevalence of TH among patients screened during a period of one year was calculated as 2.22%. Of these, 76.59% were female (<i>n</i> = 72) and 23.41% were male (<i>n</i> = 22). The rates of presentation of complaints among TH patients were 60.63% headache, 17.02% vertigo, 4.25% seizures, 3.19% tremor, 3.19% syncope, 7.44% forgetfulness, and 2.12% visual impairment. Five patients (11.76%) were admitted for metastasis investigation due to their primary malignancy; they did not have any complaints. Localization of TH: 18.08% (<i>n</i> = 17) were observed on the right side, 28.72% (<i>n</i> = 27) on the left side, and 53.19% (<i>n</i> = 50) on the bilateral tentorium leaf.</p><p><strong>Conclusions: </strong>Being aware of TH during brain MRI evaluation will help prevent possible misdiagnoses. We hope that this study with a large number of patients will increase awareness about TH, because there are no studies other than cadaver studies and a few case reports.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ec/74/PJR-87-47792.PMC9536207.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33516878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the plantar fascia in patients with diabetes mellitus: the role of sonoelastography.","authors":"Sneha Harish C,&nbsp;Rashmi Dixit,&nbsp;Sapna Singh,&nbsp;Sandeep Garg","doi":"10.5114/pjr.2022.119474","DOIUrl":"https://doi.org/10.5114/pjr.2022.119474","url":null,"abstract":"<p><strong>Purpose: </strong>It has been postulated that hyperglycaemic non-enzymatic glycation of proteins with subsequent accumulation of glycosylated end-products in tissues like the plantar fascia (PF) contributes to the development of foot ulcers in diabetics. The present study evaluates the spectrum of sonoelastographic findings in the plantar fascia in patients with type 2 diabetes mellitus (DM).</p><p><strong>Material and methods: </strong>A total of 81 patients and 32 healthy volunteers were included in the study. PF thickness was registered 1 cm distal to the attachment at the calcaneus. Greyscale ultrasonographic examination was followed by strain elastography of the PF based on which PF were qualitatively categorized into 3 grades (hard, intermediate, soft) depending on their predominant colour.</p><p><strong>Results: </strong>Patients were found to have thicker PF than healthy volunteers (<i>p</i> < 0.0001). Grade 2 (intermediate elasticity) PF was the most common type seen in both groups (48.44% of healthy volunteers and 57.25% of patients). However, a greater number of patients (36.64%) had grade 3, i.e. soft PF as compared to healthy volunteers (9.38%).</p><p><strong>Conclusions: </strong>To conclude, there is thickening and softening of the PF in patients with type 2 DM, supporting the hypo-thesis that diabetes-induced changes occur in the tissues of the foot.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/12/PJR-87-47791.PMC9536209.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33516800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Texture analysis of low-flow vascular malformations in the oral and maxillofacial region: venous malformation vs. lymphatic malformation.","authors":"Kotaro Ito,&nbsp;Hirotaka Muraoka,&nbsp;Naohisa Hirahara,&nbsp;Eri Sawada,&nbsp;Satoshi Tokunaga,&nbsp;Takashi Kaneda","doi":"10.5114/pjr.2022.119473","DOIUrl":"https://doi.org/10.5114/pjr.2022.119473","url":null,"abstract":"<p><strong>Purpose: </strong>It is challenging for radiologists to distinguish between venous malformations (VMs) and lymphatic malformations (LMs) using magnetic resonance imaging (MRI). Thus, this study aimed to differentiate VMs from LMs using non-contrast-enhanced MRI texture analysis.</p><p><strong>Material and methods: </strong>This retrospective case-control study included 12 LM patients (6 men and 6 women; mean age 43.58, range 7-85 years) and 29 VM patients (7 men and 22 women; mean age 53.10, range 19-76 years) who underwent MRI for suspected vascular malformations. LM and VM patients were identified by histopathological examination of tissues excised during surgery. The texture features of VM and LM were analysed using the open-access software MaZda version 3.3. Seventeen texture features were selected using the Fisher and probability of error and average correlation coefficient methods in MaZda from 279 original parameters calculated for VM and LM.</p><p><strong>Results: </strong>Among 17 selected texture features, the patients with LM and VM revealed significant differences in 1 histogram feature, 8 grey-level co-occurrence matrix (GLCM) features, and 1 grey-level run-length matrix feature. At the cut-off values of the histogram feature [skewness ≤ -0.131], and the GLCM features [S(0, 2) correlation ≥ 0.667, S(0, 3) correlation ≥ 0.451, S(0, 4) correlation ≥ 0.276, S(0, 5) correlation ≥ 0.389, S(1, 1) correlation ≥ 0.739, S(2, 2) correlation ≥ 0.446, S(2, -2) correlation ≥ 0.299, S(3, -3) correlation ≥ 0.091] had area under the curves of 0.724, 0.764, 0.773, 0.747, 0.733, 0.759, 0.730, 0.744 and 0.727, respectively.</p><p><strong>Conclusions: </strong>Non-contrast-enhanced MRI texture analysis allows us to differentiate between LMs and VMs.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3f/79/PJR-87-47790.PMC9536206.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33516879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of percutaneous endobilliary radiofrequency ablation with a novel temperature-controlled catheter in malignant biliary strictures.","authors":"Gulsah Yildirim,&nbsp;Hakki Muammer Karakas","doi":"10.5114/pjr.2022.119218","DOIUrl":"https://doi.org/10.5114/pjr.2022.119218","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to evaluate the efficacy and safety of temperature-controlled endobilliary radio-frequency ablation (EB-RFA) followed by metal stent placement for nonresectable malignant biliary strictures.</p><p><strong>Material and methods: </strong>From May 2017 to March 2021, 18 patients with malignant biliary obstruction who had undergone percutaneous EB-RFA and stent placement (<i>n</i> = 9) or stent placement only (<i>n</i> = 9) were included in this retrospective study. Outcomes were stent patency, technical and clinical success, overall survival, and 30-day complication rate. Kaplan-Meier and Cox regression analyses were performed to examine the relationship of EB-RFA with stent patency and overall survival.</p><p><strong>Results: </strong>The clinical and technical success rate for each group was 100%. The median stent patency was 128 days (95% CI: 122.2-133.8) in the EB-RFA group and 86 days (95% CI: 1.2-170.7) in the control group. It was significantly longer in the study group (<i>p</i> = 0.012). The mean overall survival was 267.7 ± 68.5 days (95% CI: 133.3-402.2) in the study group and 239.6 ± 33.9 days (95% CI: 173.1-306.2) in the control group. Log-rank test showed there was not a statistically significant difference in overall survival rates (<i>p</i> = 0.302). There were no major complications and no statistically significant difference in cholangitis rates (<i>p</i> = 0.620).</p><p><strong>Conclusions: </strong>Percutaneous temperature-controlled EB-RFA combined with biliary stent placement for malignant biliary obstruction can be safe and feasible, and effectively increase stent patency.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/0e/b8/PJR-87-47740.PMC9453241.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33466131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated deep learning-based segmentation of COVID-19 lesions from chest computed tomography images.","authors":"Mohammad Salehi, Mahdieh Afkhami Ardekani, Alireza Bashari Taramsari, Hamed Ghaffari, Mohammad Haghparast","doi":"10.5114/pjr.2022.119027","DOIUrl":"10.5114/pjr.2022.119027","url":null,"abstract":"<p><strong>Purpose: </strong>The novel coronavirus COVID-19, which spread globally in late December 2019, is a global health crisis. Chest computed tomography (CT) has played a pivotal role in providing useful information for clinicians to detect COVID-19. However, segmenting COVID-19-infected regions from chest CT results is challenging. Therefore, it is desirable to develop an efficient tool for automated segmentation of COVID-19 lesions using chest CT. Hence, we aimed to propose 2D deep-learning algorithms to automatically segment COVID-19-infected regions from chest CT slices and evaluate their performance.</p><p><strong>Material and methods: </strong>Herein, 3 known deep learning networks: U-Net, U-Net++, and Res-Unet, were trained from scratch for automated segmenting of COVID-19 lesions using chest CT images. The dataset consists of 20 labelled COVID-19 chest CT volumes. A total of 2112 images were used. The dataset was split into 80% for training and validation and 20% for testing the proposed models. Segmentation performance was assessed using Dice similarity coefficient, average symmetric surface distance (ASSD), mean absolute error (MAE), sensitivity, specificity, and precision.</p><p><strong>Results: </strong>All proposed models achieved good performance for COVID-19 lesion segmentation. Compared with Res-Unet, the U-Net and U-Net++ models provided better results, with a mean Dice value of 85.0%. Compared with all models, U-Net gained the highest segmentation performance, with 86.0% sensitivity and 2.22 mm ASSD. The U-Net model obtained 1%, 2%, and 0.66 mm improvement over the Res-Unet model in the Dice, sensitivity, and ASSD, respectively. Compared with Res-Unet, U-Net++ achieved 1%, 2%, 0.1 mm, and 0.23 mm improvement in the Dice, sensitivity, ASSD, and MAE, respectively.</p><p><strong>Conclusions: </strong>Our data indicated that the proposed models achieve an average Dice value greater than 84.0%. Two-dimensional deep learning models were able to accurately segment COVID-19 lesions from chest CT images, assisting the radiologists in faster screening and quantification of the lesion regions for further treatment. Nevertheless, further studies will be required to evaluate the clinical performance and robustness of the proposed models for COVID-19 semantic segmentation.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2022-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/de/c0/PJR-87-47700.PMC9453472.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33460195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of diffusion-weighted imaging in the evaluation of adnexal lesions.","authors":"Annapurna Srirambhatla,&nbsp;Roopa Devi Hosamani,&nbsp;Eshwar Chandra Nandury","doi":"10.5114/pjr.2022.119064","DOIUrl":"https://doi.org/10.5114/pjr.2022.119064","url":null,"abstract":"<p><strong>Purpose: </strong>Magnetic resonance imaging (MRI) has been used as a problem-solving tool in the diagnosis of adnexal lesions. Both benign and malignant ovarian masses can present as complex adnexal lesions. Preoperative diagnosis of malignancy is essential for planning the surgical approach and appropriate treatment regimen. The aim of our study was to determine the role of diffusion-weighted MRI (DWI) in differentiating benign from malignant adnexal lesions.</p><p><strong>Material and methods: </strong>Fifty-five patients (constituting 67 lesions) referred to MRI for evaluation of adnexal lesions were studied using 1.5 T MRI. The signal on DWI (qualitative) and ADC values (quantitative DWI) of the solid and cystic components of the lesions were analysed separately. Chi-square test, cross tabulation, and ROC curves were used to determine features on DWI that could distinguish benign from malignant lesions.</p><p><strong>Results: </strong>Of the 67 lesions, 50 were benign and 17 were malignant. There was a significant association of hyperintense signal of solid components on T2W and DWI with malignancy, with a p-value of 0.003 and 0.001, respectively. Benign lesions showed hypointense signal on T2W and DWI. ADC values of the solid components could not distinguish benign from malignant lesions; p = 0.290. The signal intensity and ADC values of the cystic fluid in benign and malignant lesions showed a significant overlap.</p><p><strong>Conclusions: </strong>Qualitative DWI acts as an adjunct to conventional MRI in differentiating benign from malignant adnexal lesions showing solid/mixed morphology. It plays no role in distinguishing lesions based on their cystic components. ADC values play no role in differentiating benign from malignant adnexal lesions irrespective of lesion morphology.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/49/1e/PJR-87-47712.PMC9453242.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33460194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An investigation of the efficacy of shear wave elastography in the characterization of benign and malignant liver lesions.","authors":"Suat Keskin,&nbsp;Ozan Babaoglu,&nbsp;Zeynep Keskin","doi":"10.5114/pjr.2022.119060","DOIUrl":"https://doi.org/10.5114/pjr.2022.119060","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate whether shear wave elastography (SWE) examination, which has recently been proposed as an accessory radiological examination technique, is effective in characterizing focal liver lesions (FLLs).</p><p><strong>Material and methods: </strong>A total of 105 patients, comprising 48 males and 57 females, underwent SWE examination. The mean age of the patients was 53.31 ± 1.59 (age range 5-87) years. The SWE measurements were obtained from FLLs that were approximately 2 to 8 cm in depth in a box that was approximately 0.5 × 1 cm wide on an ultrasonography (USG) screen from approximately 2 different locations. Receiver operating characteristic (ROC) curve analysis was performed to determine the diagnostic SWE values in the differentiation of benign and malignant lesions. Sensitivity, specificity, and positive predictive and negative predictive values were calculated in the presence of significant limit values.</p><p><strong>Results: </strong>The SWE values, in kPa and m/s, in the malignant lesions were significantly higher than those in the benign lesions (<i>p</i> = 0.006, <i>p</i> = 0.011). In the ROC curve analysis, the cut-off value was calculated as 9.005 kPa in the differentiation of malignant lesions from benign lesions. The area under the ROC curve was calculated as 0.656 in the range of 0.551-0.761 with 95% reliability. Sensitivity was calculated as 64.2%, specificity as 61.5%, positive predictive value as 63%, and negative predictive value as 62.7%.</p><p><strong>Conclusions: </strong>In addition to providing little contribution to the differentiation of benign and malignant lesions, the SWE technique is thought to contribute to a certain extent, especially in suspected cases, during the diagnosis with cross-sectional methods.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/c9/PJR-87-47711.PMC9453240.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33460197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance imaging of endometriosis: a common but often hidden, missed, and misdiagnosed entity.","authors":"Mohammad Zuber,&nbsp;Mohammad Shoaib,&nbsp;Surbhi Kumari","doi":"10.5114/pjr.2022.119032","DOIUrl":"https://doi.org/10.5114/pjr.2022.119032","url":null,"abstract":"<p><p>Endometriosis is a common benign and chronic inflammatory gynaecological disease due to functional endometrial glands and stroma in an ectopic location outside the uterine cavity. It affects 5-10% of reproductive age group women in the peak age of 24-29 years. However, women with infertility and chronic pelvic pain have an even greater prevalence, accounting for 30-50% and 90% of cases, respectively. Although it is a common entity, patients often get a delayed diagnosis because it is often subtle (hidden), missed, or confused with mimics, leading to misdiagnosis, which significantly affects patients' quality of life because they live in constant pain from undiagnosed endometriosis. Laparoscopy followed by histopathological confirmation is the gold standard for diagnosis, but it is an invasive procedure. MRI is an excellent non-invasive modality that helps in non-invasive diagnosis, with excellent delineation of the disease extent, and thus provides a presurgical mapping of the disease, which is helpful for the operating surgeon. Radiologists should be aware of all possible spectrum and diagnose this early and provide a detailed structured report mapping the entire extent of the disease process, which helps in effective treatment planning and successful outcomes in improving patients' quality of life.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/38/bb/PJR-87-47701.PMC9453474.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33460192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of apparent diffusion coefficient (ADC) in the evaluation of lymph node status in patients with locally advanced cervical cancer: our experience and a review.","authors":"Benedetta Gui,&nbsp;Luca Russo,&nbsp;Laura Minordi,&nbsp;Maura Miccò,&nbsp;Salvatore Persiani,&nbsp;Giacomo Avesani,&nbsp;Vittoria Rufini,&nbsp;Valentina Fuoco,&nbsp;Rosa Autorino,&nbsp;Gabriella Ferrandina,&nbsp;Giovanni Scambia,&nbsp;Riccardo Manfredi","doi":"10.5114/pjr.2022.118914","DOIUrl":"https://doi.org/10.5114/pjr.2022.118914","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the role of apparent diffusion coefficient (ADC) value measurement in the diagnosis of meta-static lymph nodes (LNs) in patients with locally advanced cervical cancer (LACC) and to present a systematic review of the literature.</p><p><strong>Material and methods: </strong>Magnetic resonance imaging (MRI) exams of patients with LACC were retrospectively eva-luated. Mean ADC, relative ADC (rADC), and correct ADC (cADC) values of enlarged LNs were measured and compared between positron emission tomography (PET)-positive and PET-negative LNs. Comparisons were made using the Mann-Whitney <i>U</i>-test and Student's <i>t</i>-test. ROC curves were generated for each parameter to identify the optimal cut-off value for differentiation of the LNs. A systematic search in the literature was performed, exploring several databases, including PubMed, Scopus, the Cochrane library, and Embase.</p><p><strong>Results: </strong>A total of 105 LNs in 34 patients were analysed. The median ADC value of PET-positive LNs (0.907 × 10^-3 mm²/s [0.780-1.080]) was lower than that in PET-negative LNs (1.275 × 10^-3 mm²/s [1.063-1.525]) (<i>p</i> < 0.05). rADC and cADC values were lower in PET-positive LNs (rADC: 0.120 × 10^-3 mm²/s [-0.060-0.270]; cADC: 1.130 [0.980-1.420]) than in PET-negative LNs (rADC: 0.435 × 10^-3 mm²/s [0.225-0.673]; cADC: 1.615 [1.210-1.993]) LNs (<i>p</i> < 0.05). ADC showed the highest area under the curve (AUC 0.808).</p><p><strong>Conclusions: </strong>Mean ADC, rADC, and cADC were significantly lower in the PET-positive group than in the PET-negative group. The ADC cut-off value of 1.149 × 10-3 mm²/s showed the highest sensitivity. These results confirm the usefulness of ADC in differentiating metastatic from non-metastatic LNs in LACC.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/3d/27/PJR-87-47671.PMC9453471.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33460196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}