IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02002
Julia Brigagão de Carvalho Sugai , Nayara Pelizaro Di Rito , Alexandre Lourenço , Ronei Luciano Mamoni , Ana Carolina Da Mota Falleiros , Celia Antonia Xavier de Moraes Alves , Glaucos Ricardo Paraluppi
{"title":"White piedra on pediatric scalp: A case report","authors":"Julia Brigagão de Carvalho Sugai , Nayara Pelizaro Di Rito , Alexandre Lourenço , Ronei Luciano Mamoni , Ana Carolina Da Mota Falleiros , Celia Antonia Xavier de Moraes Alves , Glaucos Ricardo Paraluppi","doi":"10.1016/j.idcr.2024.e02002","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02002","url":null,"abstract":"<div><p>This case report describes a rare fungal infection, piedra alba, in a 5-year-old female initially misdiagnosed. Treatment with 2 % ketoconazole shampoo led to significant regression within a week, without the need for hair cutting. We discuss the importance of early and accurate diagnosis, highlighting potential hair damage and complications in immunocompromised cases. Dermatoscopy aided diagnosis, and 2 % ketoconazole demonstrated efficacy, emphasizing the need for a multidisciplinary approach and dermatological follow-up.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02002"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000787/pdfft?md5=97a44a822528279e68498c672478fea3&pid=1-s2.0-S2214250924000787-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141313682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02029
Gabriel A. Godart, Sammer M. Elwasila, Ravindra V. Durvasula
{"title":"A rare case of candida osteomyelitis of the mandible associated with osteoradionecrosis and biofilm formation","authors":"Gabriel A. Godart, Sammer M. Elwasila, Ravindra V. Durvasula","doi":"10.1016/j.idcr.2024.e02029","DOIUrl":"10.1016/j.idcr.2024.e02029","url":null,"abstract":"<div><p><em>Candida</em> osteomyelitis, in general, is a relatively rare manifestation compared to its bacterial counterparts. The mandible's involvement is rarer, lacking established management and fewer guidelines. Herein, we aim to illustrate the significant challenge in treatment, namely due to the persistent and resistant nature of <em>Candida albicans</em>-associated biofilm. A multidisciplinary approach involving adjunctive use of antifungals with surgical interventions is typically necessary and feasible in this case. However, surgical interventions may not always be possible in challenging instances in which the patient may be structurally (including osteoradionecrosis) and vascularly compromised, raising questions about the feasibility of standard-of-care as well as the success of alternative therapies aimed at disrupting biofilm formation. Clinicians should maintain a high index of suspicion for complicating, deep-seated Candidiasis in at-risk populations and endeavor to treat as aggressively as possible to limit recurrent disease owing to persistence.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02029"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001057/pdfft?md5=28b58305e182e75a7496dbc9d447e7ed&pid=1-s2.0-S2214250924001057-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141729088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e01948
Ana Paula Ramírez-Acosta , Lilian Danae Acosta-Yebra , Mariela Guadalupe Macedo-Montero , Gilberto Flores-Vargas , Nicolás Padilla-Raygoza
{"title":"Survival in a pediatric patient with cerebral aspergillosis: A case report","authors":"Ana Paula Ramírez-Acosta , Lilian Danae Acosta-Yebra , Mariela Guadalupe Macedo-Montero , Gilberto Flores-Vargas , Nicolás Padilla-Raygoza","doi":"10.1016/j.idcr.2024.e01948","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01948","url":null,"abstract":"<div><p>Aspergillosis is an infrequent infection in the Central Nervous System with a mortality rate higher than 95 %. Early diagnosis is challenging and crucial. In this report, we present the case of a six-year-old female with an intense headache accompanied by left hemiparesis, gaze deviation, horizontal nystagmus, and vomiting of mucous content on five occasions. After several approaches, a cerebrospinal fluid PCR resulted positive for <em>Aspergillus</em> spp., and then management started with amphotericin B at 2.6 mg/kg/day and was managed to have voriconazole. She survived, and two years after her first hospital admission, she suffered from cerebral aspergillosis sequelae. An area of improvement is the coordination between the request and delivery of studies outside the institution. In this case, the patient´s mother did not report the analysis results on time, delaying the diagnosis.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01948"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000246/pdfft?md5=d094d59ad0529dd6463d3d1419e6f002&pid=1-s2.0-S2214250924000246-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140618547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e01985
Rasha M. Abddelgader , Sarvenaz Karamooz , Hosoon Choi , Munok Hwang , Chetan Jinadatha , Dhammika H. Navarathna
{"title":"Skin abscess caused by Trueperella bernardiae: Case report and literature review","authors":"Rasha M. Abddelgader , Sarvenaz Karamooz , Hosoon Choi , Munok Hwang , Chetan Jinadatha , Dhammika H. Navarathna","doi":"10.1016/j.idcr.2024.e01985","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01985","url":null,"abstract":"<div><p>We investigated a skin abscess caused by <em>Trueperella bernardiae</em> in a patient with comorbidities. Initial empirical therapy with Clindamycin did not yield a response, and follow-up culture revealed the presence of <em>T. bernardiae</em> through MALDI-TOF and NGS. Since no CLSI or FDA breakpoints have been published for this strain, resistant gene screening of the genetic sequence showed the presence of the erm(X) gene (with 95 % identity). This gene confers resistance to erythromycin, clindamycin, lincomycin, pristinamycin, quinupristin, and virginiamycin. Subsequent therapy with oral amoxicillin/clavulanate led to complete healing.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01985"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000611/pdfft?md5=ef2e8b2146d0e0ecb619af5b3ec71846&pid=1-s2.0-S2214250924000611-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141068249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02000
M. Hermann , C. Lisch , R. Gerth , G. Wick , D. Fries , N. Wick
{"title":"Circulating microaggregates as biomarkers for the Post‐COVID syndrome","authors":"M. Hermann , C. Lisch , R. Gerth , G. Wick , D. Fries , N. Wick","doi":"10.1016/j.idcr.2024.e02000","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02000","url":null,"abstract":"<div><p>CoVID-19 can develop into Post-COVID syndrome of potentially high morbidity, with procoagulation and reactivation of dormant viral infections being hypothesized pathophysiological mechanisms. We report on a patient suffering from fatigue, post exertional malaise, pain and neurological symptoms as a consequence of the second CoVID infection. Using live confocal microscopy on native whole blood samples we detected microaggregates of thrombocytes, leukocytes and plasma proteins in peripheral blood. In addition, there was specific cellular immunological reactivity to EBV. Upon anticoagulatory and virustatic pharmacological therapy we observed dissolution of microaggregates and significant stable clinical remission. We suggest to consider circulating microaggregates as a morphological indicator of chronic post-COVID syndrome.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e02000"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000763/pdfft?md5=22b13d83bcbdda1ace49932d7034a290&pid=1-s2.0-S2214250924000763-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141095191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e01996
Bikash Khadka , Kishor Khanal , Ashim Regmi , Anup Ghimire , Shirish KC , Rohini Nepal , on behalf of Doctors on Wheels
{"title":"Pyopericardium progressing to cardiac tamponade in a patient with dengue fever","authors":"Bikash Khadka , Kishor Khanal , Ashim Regmi , Anup Ghimire , Shirish KC , Rohini Nepal , on behalf of Doctors on Wheels","doi":"10.1016/j.idcr.2024.e01996","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01996","url":null,"abstract":"<div><p>Pyopericardium is a rare cause of cardiac tamponade. We present a case of a dengue fever patient who presented with cellulitis of the upper limbs, later manifesting cardiac tamponade, which was fatal. Although echocardiography on admission revealed a small pericardial effusion only, it later manifested as tamponade, causing cardiogenic shock. Staphylococcus pyopericardium was found later. Early identification could be possible with bedside point-of-care ultrasonography and echocardiography. Emergent pericardiocentesis or pig tail drain placement is life saving.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01996"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000726/pdfft?md5=c0e260f49ca5e2ed20ea7f22cabe140c&pid=1-s2.0-S2214250924000726-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141242258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02013
Racha Ghoussaini , Omar Abu Saleh , Hussam Tabaja
{"title":"Graft versus histoplasma disease: A case of vascular graft infection","authors":"Racha Ghoussaini , Omar Abu Saleh , Hussam Tabaja","doi":"10.1016/j.idcr.2024.e02013","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02013","url":null,"abstract":"<div><p><em>Histoplasma</em> vascular graft infection (VGI) is rarely reported, with only a handful of instances documented in the existing literature. Reporting <em>Histoplasma</em> VGI cases is important as they demonstrate previous treatment strategies and their outcomes. In this paper, we report a case of disseminated <em>histoplasmosis</em> with ascending aortic graft infection. Conservative therapy was attempted initially but failed, and our patient eventually required surgical graft explantation. Our case demonstrates the challenges in diagnosing and managing VGI caused by <em>Histoplasma capsulatum</em>.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02013"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000891/pdfft?md5=3dc43cec3783c41c5775b83eb11e98f8&pid=1-s2.0-S2214250924000891-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141487669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02017
Leigh Cervino Ahern , Daniel Nixon , Patricia Pecora Fulco
{"title":"Antiretroviral therapeutic drug monitoring in a patient with small bowel resection and new HIV diagnosis","authors":"Leigh Cervino Ahern , Daniel Nixon , Patricia Pecora Fulco","doi":"10.1016/j.idcr.2024.e02017","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02017","url":null,"abstract":"<div><p>Antiretroviral (ARV) absorption in persons living with human immunodeficiency virus (PLWH, HIV) with short bowel syndrome is limited. We describe a case of a 28-year-old male with newly diagnosed HIV and plasmablastic lymphoma with proximal jejunostomy necessitating parenteral nutrition. ARV therapy with dolutegravir 50 mg twice daily and once daily tenofovir/emtricitabine was initiated with documented malabsorption and delayed virologic suppression (VS). Dolutegravir dose titration with therapeutic drug monitoring (TDM) resulted in VS at month 12. ARV TDM with dose titration is an option for PLWH with malabsorptive states to maintain VS.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02017"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000933/pdfft?md5=b70e807f77b2bc9af6b238b14be4df48&pid=1-s2.0-S2214250924000933-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141487725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02043
Javier A. Baena-Del Valle , Sergio D. Cruz-Romero , Martha L. Romero-Prieto , Adriana A. Flórez-Vargas , Diana M. Palacios-Ortiz , Guillermo E. Quintero-Vega , Mauricio A. Palau-Lázaro
{"title":"Medical Imagery: Cytomegalovirus sialadenitis in a patient with B-cell acute lymphoblastic leukemia","authors":"Javier A. Baena-Del Valle , Sergio D. Cruz-Romero , Martha L. Romero-Prieto , Adriana A. Flórez-Vargas , Diana M. Palacios-Ortiz , Guillermo E. Quintero-Vega , Mauricio A. Palau-Lázaro","doi":"10.1016/j.idcr.2024.e02043","DOIUrl":"10.1016/j.idcr.2024.e02043","url":null,"abstract":"<div><p>Cytomegalovirus (CMV) can cause a broad range of diseases, with severity depending on immune status, comorbidities, and age. Initial CMV infection usually occurs in childhood and is typically asymptomatic, leading to lifelong latency. In immunocompromised patients, CMV can affect multiple organs, but salivary gland infections are rare. This study presents a case of a 66-year-old woman with B-cell acute lymphoblastic leukemia who developed swelling and pain in the right preauricular region during pre-transplant consolidation therapy. Despite a recent bone marrow biopsy indicating morphological remission and a flow cytometry analysis detecting only 0.04 % B lymphoblasts, she exhibited these symptoms. A CT scan revealed enlargement, hyperdensity, and enhancement of the right parotid glands, with accompanying subcutaneous edema. A biopsy of the right parotid gland showed a dense interstitial lymphoplasmacytic infiltrate with numerous Cowdry bodies and smaller granular cytoplasmic inclusions, all testing positive for CMV immunohistochemistry. The findings confirm the diagnosis of CMV sialadenitis in an immunocompromised patient. This case underscores the importance of considering CMV infections in similar clinical scenarios, particularly in patients with compromised immune systems.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02043"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001197/pdfft?md5=e9a7c6dad47f33eba12e39c79101f6a2&pid=1-s2.0-S2214250924001197-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02051
Julia S. Turock , Colette J. Matysiak Match , Kristina Adachi , Karin Nielsen-Saines , Shangxin Yang , Sanchi Malhotra
{"title":"Mycobacterium cosmeticum catheter-related bloodstream infection in an immunocompetent patient: A case report and review of the literature","authors":"Julia S. Turock , Colette J. Matysiak Match , Kristina Adachi , Karin Nielsen-Saines , Shangxin Yang , Sanchi Malhotra","doi":"10.1016/j.idcr.2024.e02051","DOIUrl":"10.1016/j.idcr.2024.e02051","url":null,"abstract":"<div><h3>Background</h3><p><em>Mycobacterium cosmeticum</em> is an emerging rapidly growing mycobacteria (RGM) species that has been rarely reported to cause human disease. RGM catheter-related bloodstream infections (CRBSI) are often challenging to treat given the need for line removal, variable species-dependent antimicrobial susceptibility, combination antimicrobial treatment, and historically longer courses of antibiotics.</p></div><div><h3>Case presentation</h3><p>We present a case of an immunocompetent pediatric patient with severe hemophilia B and <em>M. cosmeticum</em> CRBSI. While the patient’s hemophilia B precluded a standard line holiday, he successfully cleared his infection with two line exchanges followed by two weeks of antibiotics.</p></div><div><h3>Conclusions</h3><p>RGM, including emerging species <em>M. cosmeticum</em>, may be considered in patients with an indolent presentation of CRBSI. Our case suggests source control with shorter courses of antimicrobials can be successful.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02051"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001276/pdfft?md5=9b886bd4bcb567e6fbf91d8d92fd4bd7&pid=1-s2.0-S2214250924001276-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}