IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02230

Rahel T. Zewude , Matheus O. Bastos , May AlFalahi , Coleman M.F. Rotstein , Carson K.L. Lo

{"title":"Holy water not so holy: Potential source of Elizabethkingia pneumonia and bacteremia in an immunocompromised host","authors":"Rahel T. Zewude , Matheus O. Bastos , May AlFalahi , Coleman M.F. Rotstein , Carson K.L. Lo","doi":"10.1016/j.idcr.2025.e02230","DOIUrl":"10.1016/j.idcr.2025.e02230","url":null,"abstract":"<div><div><em>Elizabethkingia</em> species are Gram-negative, glucose-non-fermenting bacilli predominantly found in soil and water, with <em>Elizabethkingia anophelis</em> increasingly recognized as a human pathogen. <em>E. anophelis</em> has also been reported in hospital outbreaks, suggesting the potential role of contaminated institutional water sources. Conventional microbiological methods often lead to misidentifying this pathogen for other members of the genus <em>Elizabethkingia</em>, suggesting a role for molecular methods for identification.</div><div>We report a 67-year-old female who developed multiorgan failure requiring intensive care unit admission and mechanical ventilation while being treated with chemotherapy for Burkitt lymphoma. She developed pneumonia with Gram-negative bacilli isolated from her endotracheal aspirate culture, later identified as <em>E. anophelis</em>. She later developed bacteremia due to the same pathogen, which was confirmed by MALDI-TOF and whole genome sequencing. Waterborne transmission via holy water administration was postulated to be potential source of infection.</div><div>Our case report highlights that <em>E. anophelis</em> may cause significant infection and should not be disregarded as contaminant, especially in immunosuppressed individuals. As a waterborne pathogen that may be brought into hospital environments, emphasis on educating family members, close nursing monitoring, and reporting of suspected, unsupervised manipulation of medical equipment should be undertaken to prevent contamination by this organism from outside sources.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02230"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143839061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Septic shock caused by emphysematous hepatitis complicated with intracranial infection 肺气肿性肝炎致感染性休克并发颅内感染

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02159

Miao Chen , Jianbo Chen , Zhengzhi Zhuang , Xiaojun He , Yue Wang , Junwen Liang , Runpei Lin , Gengxin Cai

{"title":"Septic shock caused by emphysematous hepatitis complicated with intracranial infection","authors":"Miao Chen , Jianbo Chen , Zhengzhi Zhuang , Xiaojun He , Yue Wang , Junwen Liang , Runpei Lin , Gengxin Cai","doi":"10.1016/j.idcr.2025.e02159","DOIUrl":"10.1016/j.idcr.2025.e02159","url":null,"abstract":"<div><h3>Purpose</h3><div>Emphysematous hepatitis is an uncommon and life-threatening hepatic infection, characterized by the presence of gas within the liver and high mortality. There are few reports of this condition.</div></div><div><h3>Method</h3><div>We report a case of septic shock caused by emphysematous hepatitis complicated with intracranial infection, and review the current literature on emphysematous hepatitis.</div></div><div><h3>Results</h3><div>A 57-year-old male with uncontrolled diabetes mellitus developed emphysematous hepatitis complicated with intracranial infection, which progressed to septic shock. The patient was treated with antibiotics and received percutaneous liver puncture drainage early and was discharged preferably in remission. From the literature review, we found 16 previously published cases of emphysematous hepatitis.</div></div><div><h3>Conclusion</h3><div>Given our experience and the literature review, percutaneous liver puncture drainage or surgical treatment in the early stage may be beneficial to patients with emphysematous hepatitis.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02159"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143341018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influenza A Virus Complicated by Myopericarditis with Pericardial Effusion 甲型流感病毒并发心包炎伴心包积液。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02158

Dhara Rana , Anson Marsh , Mahum Sami , Hiral Shukla , Dimitris Barbouletos , Nicholas Calder

{"title":"Influenza A Virus Complicated by Myopericarditis with Pericardial Effusion","authors":"Dhara Rana , Anson Marsh , Mahum Sami , Hiral Shukla , Dimitris Barbouletos , Nicholas Calder","doi":"10.1016/j.idcr.2025.e02158","DOIUrl":"10.1016/j.idcr.2025.e02158","url":null,"abstract":"<div><div>Influenza A viral infection classically presents as pulmonary manifestations which often require symptomatic management. It can rarely be complicated by pericarditis with concurrent pericardial effusion. We present a unique case of myopericarditis with a pericardial effusion caused by Influenza A. Our patient was presented with elevated troponin and BNP. Chest x-ray showed an enlargement of the cardiac silhouette and clear lungs. CT angiography was remarkable for pericardial effusion. An echocardiogram was performed which demonstrated mild concentric left ventricular hypertrophy with small to moderate circumferential pericardial effusion, and no echocardiographic signs of cardiac tamponade. The significance of our case makes clinicians aware that acute myopericarditis with concurrent pericardial effusion can lead to fatal complications such as cardiac tamponade or cardiogenic shock if left untreated. Early diagnosis and treatment as presented in our case could reduce the risk of such severe cardiac events from occurring.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02158"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Veillonella atypica bacteraemia: Case report and literature review 非典型细孔菌血症1例报告并文献复习

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02194

Miguel Franco Álvarez , Andrea Jardi Cuadrado , Mariño Francisco Fernández Cambeiro , Adrián Domínguez Lago , José Antonio Díaz Peromingo

引用次数: 0

Diagnosis of cystoisosporiasis in a patient with HIV and modestly decreased CD4 counts 诊断囊异孢子虫病的患者与艾滋病毒和适度降低CD4计数

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02259

Kevin Kurator , Leona Mason , David Bruckner , Hongying Tan , Glenn Mathisen

引用次数: 0

Severe fever with thrombocytopenia syndrome (Dabie bandavirus infection) 发热伴血小板减少综合征（大别班达病毒感染）

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02254

Zhuo Wang

引用次数: 0

Bloodstream infection caused by Erysipelothrix rhusiopathiae serotype 6: Case report and literature review 6型红喉丹毒致血液感染1例并文献复习

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02329

Asumi Suzuki, Mariko Hakamata, Syunya Tanikawa, Naoto Kanno, Ikumi Yamagishi, Masahiro Ui, Hayato Tsuruma, Yuuki Bamba, Hideyuki Ogata, Satoshi Shibata, Hiromi Cho, Mizuho Sato, Nobumasa Aoki, Hiroshi Moro, Toshiaki Kikuchi

{"title":"Bloodstream infection caused by Erysipelothrix rhusiopathiae serotype 6: Case report and literature review","authors":"Asumi Suzuki, Mariko Hakamata, Syunya Tanikawa, Naoto Kanno, Ikumi Yamagishi, Masahiro Ui, Hayato Tsuruma, Yuuki Bamba, Hideyuki Ogata, Satoshi Shibata, Hiromi Cho, Mizuho Sato, Nobumasa Aoki, Hiroshi Moro, Toshiaki Kikuchi","doi":"10.1016/j.idcr.2025.e02329","DOIUrl":"10.1016/j.idcr.2025.e02329","url":null,"abstract":"<div><div><em>Erysipelothrix rhusiopathiae</em> is a zoonotic, facultatively anaerobic, non-spore-forming, gram-positive bacillus. Although the serotypes and phylogenetic clades of <em>E. rhusiopathiae</em> strains isolated from animals have been shown to be closely related, the serotype identification of clinical isolates from human patients remains limited. We report a case of a 66-year-old woman with bacteremia caused by <em>E. rhusiopathiae</em> serotype 6. The patient had been admitted with aspiration pneumonia and heat stroke. She had no animal-related occupational history and had been receiving long-term oral prednisolone therapy for mixed connective tissue disease. Upon confirmation of <em>E. rhusiopathiae</em> positivity on blood cultures, she was treated with intravenous ampicillin for 10 days and achieved complete recovery. Agar gel precipitation and polymerase chain reaction tests identified the isolate as serotype 6. Surface protective antigen (Spa) typing by sequence analysis suggested a marine animal origin of infection. To the best of our knowledge, this is the first reported case of bacteremia caused by <em>E. rhusiopathiae</em> serotype 6 in humans. Spa typing through sequence analysis may provide variable information for identifying the infection source. <em>E. rhusiopathiae</em> carrying the <em>SpaB</em> gene should be considered in immunosuppressed patients, regardless of animal exposure history. Further studies are needed to elucidate the epidemiological distribution of serotypes among human clinical isolates.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02329"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144704006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular diagnosis of campylobacter splenic abscess in an immunocompetent adolescent: A case report and literature review 免疫功能正常青少年弯曲杆菌性脾脓肿的分子诊断：1例报告及文献复习

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02316

Sabeen Zara , Junais Koleri , Maisa Ali , Fatma Abid , Jabeed Parengal , Manal Mahmoud Hamed , Muna Al Maslamani

引用次数: 0

Limited efficacy of adjunctive therapy in a case of severe herpes simplex virus encephalitis: A case report and literature review 1例严重单纯疱疹病毒脑炎的辅助治疗效果有限：1例报告及文献复习

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02307

Xiao-Ling Zhong, Chen-Li Yang, Xiao-Long Yu, Ling Wang

{"title":"Limited efficacy of adjunctive therapy in a case of severe herpes simplex virus encephalitis: A case report and literature review","authors":"Xiao-Ling Zhong, Chen-Li Yang, Xiao-Long Yu, Ling Wang","doi":"10.1016/j.idcr.2025.e02307","DOIUrl":"10.1016/j.idcr.2025.e02307","url":null,"abstract":"<div><div>Herpes simplex virus-1 (HSV-1) encephalitis is a severe neurological disease with high mortality and morbidity despite antiviral therapy. The role of adjunctive immunomodulatory treatments like intravenous immunoglobulin (IVIG) and glucocorticoids remains uncertain. We report a fatal case of severe HSV-1 encephalitis in a 59-year-old man who developed hemorrhagic necrosis despite combined treatment with acyclovir, IVIG (0.4 g/kg/day), and methylprednisolone (80 mg/day). CSF PCR and MRI confirmed the diagnosis, with subsequent imaging showing progressive left hemispheric hemorrhage requiring surgical evacuation. The patient deteriorated neurologically and died on day 56. This case adds to growing evidence questioning the efficacy of adjunctive IVIG/steroids in advanced HSV-1 encephalitis, particularly with hemorrhagic complications. While some studies suggest potential benefits during the inflammatory phase, our experience highlights their limitations in critical cases. More research is needed to identify which patients might benefit from immunomodulation and optimal treatment timing.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02307"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144523901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An unusual clinical presentation of Cryptococcal meningitis: The importance of a detailed history and physical 隐球菌性脑膜炎的罕见临床表现：详细病史和体格检查的重要性

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02311

Shay Nakahira , Marcus Yamamoto , Terry Wood

{"title":"An unusual clinical presentation of Cryptococcal meningitis: The importance of a detailed history and physical","authors":"Shay Nakahira , Marcus Yamamoto , Terry Wood","doi":"10.1016/j.idcr.2025.e02311","DOIUrl":"10.1016/j.idcr.2025.e02311","url":null,"abstract":"<div><h3>Purpose</h3><div>Cryptococcal meningitis is a severe fungal infection that can present with a highly variable range of neuro-ophthalmic and systemic symptoms. Although more classically associated with immunocompromised individuals, it has increasingly been reported in immunocompetent hosts. Cryptococcus neoformans is typically linked to opportunistic infections in immunosuppressed populations, whereas Cryptococcus gattii more commonly affects immunocompetent individuals.</div></div><div><h3>Observations</h3><div>A healthy 40-year-old female presented with new onset recurrent headaches. After a normal MRI, she was re-assured by multiple physicians and given a presumptive diagnosis of stress induced migraine, as she had recently experienced the sudden unexpected death of her husband. Persistent and progressive headaches, focusing difficulties, and extreme photosensitivity prompted her to seek further evaluation by an ophthalmologist, who diagnosed her with Cryptococcal meningitis based on her lumbar puncture results.</div></div><div><h3>Discussion and importance</h3><div>Despite the initial clinical impression being suggestive of migraines, the patient was ultimately diagnosed with cryptococcal meningitis one month from the initial onset of her symptoms, with rapid advancement to an emergent situation ultimately resulting in two hospitalizations where she received numerous spinal fluid drainages, anti-fungal medications and a lumbar shunt. This case underscores the importance of comprehensive history-taking, clinical vigilance, and maintaining a broad differential diagnosis in the workup of any patient. Ocular symptoms, in this instance, served as an early manifestation of cryptococcal meningitis in an immunocompetent patient, highlighting the need for heightened awareness in clinical practice to ensure timely diagnosis and appropriate management.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02311"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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