IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02158

Dhara Rana , Anson Marsh , Mahum Sami , Hiral Shukla , Dimitris Barbouletos , Nicholas Calder

{"title":"Influenza A Virus Complicated by Myopericarditis with Pericardial Effusion","authors":"Dhara Rana , Anson Marsh , Mahum Sami , Hiral Shukla , Dimitris Barbouletos , Nicholas Calder","doi":"10.1016/j.idcr.2025.e02158","DOIUrl":"10.1016/j.idcr.2025.e02158","url":null,"abstract":"<div><div>Influenza A viral infection classically presents as pulmonary manifestations which often require symptomatic management. It can rarely be complicated by pericarditis with concurrent pericardial effusion. We present a unique case of myopericarditis with a pericardial effusion caused by Influenza A. Our patient was presented with elevated troponin and BNP. Chest x-ray showed an enlargement of the cardiac silhouette and clear lungs. CT angiography was remarkable for pericardial effusion. An echocardiogram was performed which demonstrated mild concentric left ventricular hypertrophy with small to moderate circumferential pericardial effusion, and no echocardiographic signs of cardiac tamponade. The significance of our case makes clinicians aware that acute myopericarditis with concurrent pericardial effusion can lead to fatal complications such as cardiac tamponade or cardiogenic shock if left untreated. Early diagnosis and treatment as presented in our case could reduce the risk of such severe cardiac events from occurring.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02158"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Veillonella atypica bacteraemia: Case report and literature review 非典型细孔菌血症1例报告并文献复习

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02194

Miguel Franco Álvarez , Andrea Jardi Cuadrado , Mariño Francisco Fernández Cambeiro , Adrián Domínguez Lago , José Antonio Díaz Peromingo

引用次数: 0

Diagnosis of cystoisosporiasis in a patient with HIV and modestly decreased CD4 counts 诊断囊异孢子虫病的患者与艾滋病毒和适度降低CD4计数

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02259

Kevin Kurator , Leona Mason , David Bruckner , Hongying Tan , Glenn Mathisen

引用次数: 0

Severe fever with thrombocytopenia syndrome (Dabie bandavirus infection) 发热伴血小板减少综合征（大别班达病毒感染）

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02254

Zhuo Wang

引用次数: 0

Prolonged acyclovir therapy for Herpes simplex virus (HSV)-1–associated hepatitis in an immunocompetent man 延长阿昔洛韦治疗单纯疱疹病毒(HSV)-1相关肝炎的免疫功能正常的人

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02293

Oulfa Boussetta-Charfi , François Duprey , Rémi Balluet , Marie-France Lutz , Sylvie Gonzalo , Anne-Camille Faure , Annie Evers , Sara Chenafi-Adham , Elisabeth Botelho-Nevers , Guillaume Dupont , Thomas Bourlet , David Boutolleau , Sylvie Pillet

{"title":"Prolonged acyclovir therapy for Herpes simplex virus (HSV)-1–associated hepatitis in an immunocompetent man","authors":"Oulfa Boussetta-Charfi , François Duprey , Rémi Balluet , Marie-France Lutz , Sylvie Gonzalo , Anne-Camille Faure , Annie Evers , Sara Chenafi-Adham , Elisabeth Botelho-Nevers , Guillaume Dupont , Thomas Bourlet , David Boutolleau , Sylvie Pillet","doi":"10.1016/j.idcr.2025.e02293","DOIUrl":"10.1016/j.idcr.2025.e02293","url":null,"abstract":"<div><div>Herpes simplex virus (HSV)-associated hepatitis (HH) has rarely been reported in immunocompetent patients. In the absence of mucocutaneous lesions and because of nonspecific biological features such as hepatic cytolysis, its diagnosis can be missed, leading to delayed acyclovir initiation and potentially poor outcomes. We report a case of a 62-year-old immunocompetent man who developed severe HH following a primary HSV-1 infection, diagnosed by a very high plasma HSV-1 DNA load. His condition was complicated by macrophage activation syndrome, which was managed using chemotherapy and corticosteroids. Acyclovir therapy (10 mg/kg every 8 ,h) was extended to Day 74 to a persistently detectable plasma HSV-1 DNA load, despite the normalisation of liver function tests. However, the optimal duration of antiviral therapy for HH remains unclear, as prolonged treatment may increase the risk of nephrotoxicity, whereas premature discontinuation may lead to fatal outcomes. Overall, this case illustrates that discontinuation of acyclovir did not result in a rebound of HSV-1 viraemia despite the persistent detection of low viral DNA load. Clinical and biological resolution of hepatitis may be helpful in guiding the decision to discontinue antiviral therapy. This case highlights the importance of early molecular diagnosis in atypical presentations of HH and contributes to guiding management strategies, particularly regarding antiviral treatment duration.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02293"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144330717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An unusual case of varicella zoster encephalitis mimicking a glioblastoma on magnetic resonance imaging and magnetic resonance spectroscopy 一个不寻常的水痘带状疱疹脑炎模拟胶质母细胞瘤的磁共振成像和磁共振波谱。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02124

Brenden Nago , Jeffrey E. Liu

引用次数: 0

A rare case of Gardnerella vaginalis spondylodiscitis 罕见的阴道加德纳菌性脊柱炎1例。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02126

Alex Belote, Kassem Hammoud

{"title":"A rare case of Gardnerella vaginalis spondylodiscitis","authors":"Alex Belote, Kassem Hammoud","doi":"10.1016/j.idcr.2024.e02126","DOIUrl":"10.1016/j.idcr.2024.e02126","url":null,"abstract":"<div><div>A 55-year-old-male with a chronic left uretero-pelvic junction (UPJ) obstruction managed with intermittent stent exchanges presented with low midline back pain. CT Abdomen/Pelvis revealed spondylodiscitis at L4-L5, further demonstrated on MRI Lumbar spine. Imaging also revealed the left nephro-ureteral stent was mispositioned, with some mild wall thickening of the left ureter. He was not systemically ill, and antimicrobials were held. He underwent a L4/5 disc biopsy, and pathology revealed acute discitis. Blood and biopsy cultures remained negative through hospital day 5. He then underwent repeat L4/5 disc biopsy. Cultures of repeat biopsy resulted in <em>Gardnerella vaginalis</em>. IV antimicrobials were stopped, and oral Metronidazole was started. He completed 10 weeks of Metronidazole therapy, with significant clinical improvement.</div><div><em>G. vaginalis</em> is a rare cause of bone and joint infections. It is difficult to culture and is less virulent than common bacteria associated with native vertebral osteomyelitis. There have been few case reports of <em>G. vaginalis</em> osteomyelitis or prosthetic joint infection, especially in males. <em>G. vaginalis</em> can rarely colonize the urethra in men and has been known to form biofilm on foreign material in the female genitourinary system. We suspect our patient had developed colonization of his ureteral stent, predisposing him to osteomyelitis. Were repeat biopsy not pursued in this case, our patient likely could have developed empiric treatment failure. Holding antibiotics after initial biopsy proved highly beneficial.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02126"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges 揭露结核性关节炎在假体关节：诊断和治疗的挑战。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02134

Asbah Rahman, Aastha Randhawa, Yu Shia Lin

引用次数: 0

Diagnosis of disseminated cryptococcosis via iliac bone marrow aspirate analysis 髂骨髓抽吸分析诊断播散性隐球菌病。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02136

Weibu Chen, Xueyan Chen

引用次数: 0

Emergence of Coccidioides posadasii in an asymptomatic Ecuadorian patient with diabetes: A case report 厄瓜多尔无症状糖尿病患者出现波萨达球虫一例报告。