IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02013
Racha Ghoussaini , Omar Abu Saleh , Hussam Tabaja
{"title":"Graft versus histoplasma disease: A case of vascular graft infection","authors":"Racha Ghoussaini , Omar Abu Saleh , Hussam Tabaja","doi":"10.1016/j.idcr.2024.e02013","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02013","url":null,"abstract":"<div><p><em>Histoplasma</em> vascular graft infection (VGI) is rarely reported, with only a handful of instances documented in the existing literature. Reporting <em>Histoplasma</em> VGI cases is important as they demonstrate previous treatment strategies and their outcomes. In this paper, we report a case of disseminated <em>histoplasmosis</em> with ascending aortic graft infection. Conservative therapy was attempted initially but failed, and our patient eventually required surgical graft explantation. Our case demonstrates the challenges in diagnosing and managing VGI caused by <em>Histoplasma capsulatum</em>.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000891/pdfft?md5=3dc43cec3783c41c5775b83eb11e98f8&pid=1-s2.0-S2214250924000891-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141487669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02043
Javier A. Baena-Del Valle , Sergio D. Cruz-Romero , Martha L. Romero-Prieto , Adriana A. Flórez-Vargas , Diana M. Palacios-Ortiz , Guillermo E. Quintero-Vega , Mauricio A. Palau-Lázaro
{"title":"Medical Imagery: Cytomegalovirus sialadenitis in a patient with B-cell acute lymphoblastic leukemia","authors":"Javier A. Baena-Del Valle , Sergio D. Cruz-Romero , Martha L. Romero-Prieto , Adriana A. Flórez-Vargas , Diana M. Palacios-Ortiz , Guillermo E. Quintero-Vega , Mauricio A. Palau-Lázaro","doi":"10.1016/j.idcr.2024.e02043","DOIUrl":"10.1016/j.idcr.2024.e02043","url":null,"abstract":"<div><p>Cytomegalovirus (CMV) can cause a broad range of diseases, with severity depending on immune status, comorbidities, and age. Initial CMV infection usually occurs in childhood and is typically asymptomatic, leading to lifelong latency. In immunocompromised patients, CMV can affect multiple organs, but salivary gland infections are rare. This study presents a case of a 66-year-old woman with B-cell acute lymphoblastic leukemia who developed swelling and pain in the right preauricular region during pre-transplant consolidation therapy. Despite a recent bone marrow biopsy indicating morphological remission and a flow cytometry analysis detecting only 0.04 % B lymphoblasts, she exhibited these symptoms. A CT scan revealed enlargement, hyperdensity, and enhancement of the right parotid glands, with accompanying subcutaneous edema. A biopsy of the right parotid gland showed a dense interstitial lymphoplasmacytic infiltrate with numerous Cowdry bodies and smaller granular cytoplasmic inclusions, all testing positive for CMV immunohistochemistry. The findings confirm the diagnosis of CMV sialadenitis in an immunocompromised patient. This case underscores the importance of considering CMV infections in similar clinical scenarios, particularly in patients with compromised immune systems.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001197/pdfft?md5=e9a7c6dad47f33eba12e39c79101f6a2&pid=1-s2.0-S2214250924001197-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02051
Julia S. Turock , Colette J. Matysiak Match , Kristina Adachi , Karin Nielsen-Saines , Shangxin Yang , Sanchi Malhotra
{"title":"Mycobacterium cosmeticum catheter-related bloodstream infection in an immunocompetent patient: A case report and review of the literature","authors":"Julia S. Turock , Colette J. Matysiak Match , Kristina Adachi , Karin Nielsen-Saines , Shangxin Yang , Sanchi Malhotra","doi":"10.1016/j.idcr.2024.e02051","DOIUrl":"10.1016/j.idcr.2024.e02051","url":null,"abstract":"<div><h3>Background</h3><p><em>Mycobacterium cosmeticum</em> is an emerging rapidly growing mycobacteria (RGM) species that has been rarely reported to cause human disease. RGM catheter-related bloodstream infections (CRBSI) are often challenging to treat given the need for line removal, variable species-dependent antimicrobial susceptibility, combination antimicrobial treatment, and historically longer courses of antibiotics.</p></div><div><h3>Case presentation</h3><p>We present a case of an immunocompetent pediatric patient with severe hemophilia B and <em>M. cosmeticum</em> CRBSI. While the patient’s hemophilia B precluded a standard line holiday, he successfully cleared his infection with two line exchanges followed by two weeks of antibiotics.</p></div><div><h3>Conclusions</h3><p>RGM, including emerging species <em>M. cosmeticum</em>, may be considered in patients with an indolent presentation of CRBSI. Our case suggests source control with shorter courses of antimicrobials can be successful.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001276/pdfft?md5=9b886bd4bcb567e6fbf91d8d92fd4bd7&pid=1-s2.0-S2214250924001276-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02029
Gabriel A. Godart, Sammer M. Elwasila, Ravindra V. Durvasula
{"title":"A rare case of candida osteomyelitis of the mandible associated with osteoradionecrosis and biofilm formation","authors":"Gabriel A. Godart, Sammer M. Elwasila, Ravindra V. Durvasula","doi":"10.1016/j.idcr.2024.e02029","DOIUrl":"10.1016/j.idcr.2024.e02029","url":null,"abstract":"<div><p><em>Candida</em> osteomyelitis, in general, is a relatively rare manifestation compared to its bacterial counterparts. The mandible's involvement is rarer, lacking established management and fewer guidelines. Herein, we aim to illustrate the significant challenge in treatment, namely due to the persistent and resistant nature of <em>Candida albicans</em>-associated biofilm. A multidisciplinary approach involving adjunctive use of antifungals with surgical interventions is typically necessary and feasible in this case. However, surgical interventions may not always be possible in challenging instances in which the patient may be structurally (including osteoradionecrosis) and vascularly compromised, raising questions about the feasibility of standard-of-care as well as the success of alternative therapies aimed at disrupting biofilm formation. Clinicians should maintain a high index of suspicion for complicating, deep-seated Candidiasis in at-risk populations and endeavor to treat as aggressively as possible to limit recurrent disease owing to persistence.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001057/pdfft?md5=28b58305e182e75a7496dbc9d447e7ed&pid=1-s2.0-S2214250924001057-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141729088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02057
S. Jawad Zafar , Zachary Wynne , Thomas John , Lauren Groft Buzzalino , Akira A. Shishido , David J. Riedel
{"title":"Cefazolin-induced hemolytic anemia in septic arthritis: A case report","authors":"S. Jawad Zafar , Zachary Wynne , Thomas John , Lauren Groft Buzzalino , Akira A. Shishido , David J. Riedel","doi":"10.1016/j.idcr.2024.e02057","DOIUrl":"10.1016/j.idcr.2024.e02057","url":null,"abstract":"<div><p>A 50-year-old woman living with untreated HIV and injection drug use presented with right shoulder pain. The shoulder exam and computed tomography (CT) scan were concerning for septic arthritis. She was started on empiric vancomycin and cefepime and underwent right shoulder debridement and humeral head resection. Bone cultures grew methicillin sensitive <em>Staphylococcus aureus</em> (MSSA); empiric broad-spectrum antibiotics were changed to cefazolin. The patient subsequently developed severe anemia refractory to blood transfusions approximately 6 days later. Further evaluation disclosed hemolytic anemia attributable to cefazolin. Antibiotic therapy was switched from cefazolin to daptomycin, and the patient was started on prednisone. She had sustained improvement in hemoglobin values above 6 g/dL without requiring further transfusions prior to hospital discharge. Drug-induced immune hemolytic anemia from cefazolin is rare but has been reported primarily in the perioperative setting. Here, we present a case following initiation of treatment for septic arthritis.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001331/pdfft?md5=fc10850bc36aaf21a9b683eaecf81019&pid=1-s2.0-S2214250924001331-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141985033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound findings of Fitz-Hugh-Curtis Syndrome (FHCS) associated with splenic tuberculosis in an HIV-positive male patient","authors":"Ibrahima Niang , Daouda Thioub , Mamadou Ly , Abdourahmane Ndong , Fallou Galass Niang , Abdoulaye Dione Diop , Sokhna Ba","doi":"10.1016/j.idcr.2024.e02036","DOIUrl":"10.1016/j.idcr.2024.e02036","url":null,"abstract":"<div><p>Fitz-Hugh-Curtis (FHCS) is characterized by an inflammation of the hepatic capsule concomitant or following pelvic infection due to <em>Chlamydia trachomatis</em> or <em>Neisseria gonorrhea</em>. It is a rare condition occurring most often in a woman of childbearing age and very rare in male patients. Splenic involvement is also a rare form of abdominal tuberculosis. The association of these two conditions is very uncommon. We report the exceptional case of a 58- year-old HIV-positive male patient, with whom abdominal ultrasound helped diagnose FHCS associated with abdominal tuberculosis invovlving the spleen.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001124/pdfft?md5=a4fb7863f78bfd6f08eb04bfa5b99aec&pid=1-s2.0-S2214250924001124-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141963007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02073
Ashton D. Hall , Joshua M. Ferreri , Jennifer E. Baker , Eleanor A. Powell , Imran Ahmed , Timothy T. Klostermeier , Keith M. Luckett
{"title":"Clostridial gas gangrene involving the brain, gallbladder, heart, and soft tissue: A case report and literature review","authors":"Ashton D. Hall , Joshua M. Ferreri , Jennifer E. Baker , Eleanor A. Powell , Imran Ahmed , Timothy T. Klostermeier , Keith M. Luckett","doi":"10.1016/j.idcr.2024.e02073","DOIUrl":"10.1016/j.idcr.2024.e02073","url":null,"abstract":"<div><p>Clostridial gas gangrene (CGG) is among the most rapidly spreading infections in humans, with mortality rates approaching 100 % if not treated promptly. Most cases follow traumatic inoculation, although spontaneous infections occur in a minority of patients with immunodeficiency. Spontaneous CGG is primarily caused by <em>Clostridium septicum</em>, whereas traumatic infection is associated with <em>Clostridium perfringens</em>. Patients with CGG present abruptly with rapidly progressive symptoms, underscoring the importance of early recognition, prompt surgical intervention, and appropriate antimicrobial therapy. We describe an illustrative case of spontaneous CGG caused by <em>C. perfringens</em> in a polymorbid 73-year-old female patient. Despite aggressive medical and surgical management, she succumbed to metastatic infection within 48 h of presentation.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001495/pdfft?md5=0f086d239b55083580bb1cff5f7ad56d&pid=1-s2.0-S2214250924001495-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142171761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02026
Nathan B. Price , Emily S. Cormack , Kathryn R. Matthias , Kareem W. Shehab
{"title":"Chronic paronychia associated with fluconazole use in two pediatric patients with coccidioidomycosis","authors":"Nathan B. Price , Emily S. Cormack , Kathryn R. Matthias , Kareem W. Shehab","doi":"10.1016/j.idcr.2024.e02026","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02026","url":null,"abstract":"<div><p>Azoles are frequently used to treat systemic mycoses but have been associated with a number of adverse effects of the skin and skin appendages. Herein we describe two cases of chronic paronychia in pediatric patients receiving fluconazole for coccidioidomycosis. Their clinical characteristics are described, and the literature reviewed.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001021/pdfft?md5=aa5a9af2af549bff7c108e1acc30ebe0&pid=1-s2.0-S2214250924001021-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141596509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e02019
Abdullah Balkhair , Badriya Al Adawi , Prashanth Kumar , Saja Mohammed , Saleh Baawain , Ruqaiya Al Harrasi , Glenneth Gallenero
{"title":"Melioidosis in a returned traveler: Case report and review of the imported cases in Oman","authors":"Abdullah Balkhair , Badriya Al Adawi , Prashanth Kumar , Saja Mohammed , Saleh Baawain , Ruqaiya Al Harrasi , Glenneth Gallenero","doi":"10.1016/j.idcr.2024.e02019","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02019","url":null,"abstract":"<div><p>Melioidosis is an emerging tropical infectious disease in travelers. We present a case of travel related melioidosis in a 65-year-old man with chronic obstructive pulmonary disease and end stage renal disease following a two-week business trip to Thailand and attendance of the Songkran festival. This case emphasizes that vigilance, heightened clinical suspicion, and use of appropriate microbiology diagnostic tools are of paramount importance for a timely diagnosis and successful management. With the ever-increasing global travel, infectious diseases specialists, microbiologists, and public health professionals are constantly challenged by unfamiliar infections in returned travelers.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":null,"pages":null},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000957/pdfft?md5=5816a6cfcf7dffc6fbcd5a639847f24d&pid=1-s2.0-S2214250924000957-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141596511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2024-01-01DOI: 10.1016/j.idcr.2024.e01979
Angela McGaugh , William Russell , Erin Boswell
{"title":"Turicella otitidis hypoglossal nerve stimulator device associated infection","authors":"Angela McGaugh , William Russell , Erin Boswell","doi":"10.1016/j.idcr.2024.e01979","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01979","url":null,"abstract":"<div><p>71-year-old male with history of obstructive sleep apnea presented with persistent drainage from the surgical incision site over the recently implanted hypoglossal nerve stimulator. Wound cultures from device pocket identified the pathogen as <em>Turicella otitidis</em>. Clinical course included treatment with broad-spectrum intravenous antibiotics and device explantation. This case is the first known <em>T. otitidis</em> device associated infection.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000556/pdfft?md5=bf57345589c0cf2864c8355022845aaf&pid=1-s2.0-S2214250924000556-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140893385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}