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Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges 揭露结核性关节炎在假体关节:诊断和治疗的挑战。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02134
Asbah Rahman, Aastha Randhawa, Yu Shia Lin
{"title":"Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges","authors":"Asbah Rahman,&nbsp;Aastha Randhawa,&nbsp;Yu Shia Lin","doi":"10.1016/j.idcr.2024.e02134","DOIUrl":"10.1016/j.idcr.2024.e02134","url":null,"abstract":"<div><div>An 85-year-old woman with a history of total knee replacements for osteoarthritis in the past, presented with left knee swelling and pain that persisted for 14 months. An initial diagnosis of synovial cyst was made, and she underwent multiple aspirations and symptomatic treatments without improvement. Repeat arthrocentesis showed a WBC of 56,000/μL with 61 % neutrophils and 34 % lymphocytes. Synovial fluid bacterial and fungal cultures were negative. The acid-fast bacilli (AFB) culture revealed the Mycobacterium tuberculosis complex and was confirmed by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) Mass Spectrometry. This case highlights the challenges of diagnosing tuberculous prosthetic joint infection in an elderly individual with knee pain.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02134"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11722171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis of disseminated cryptococcosis via iliac bone marrow aspirate analysis 髂骨髓抽吸分析诊断播散性隐球菌病。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02136
Weibu Chen, Xueyan Chen
{"title":"Diagnosis of disseminated cryptococcosis via iliac bone marrow aspirate analysis","authors":"Weibu Chen,&nbsp;Xueyan Chen","doi":"10.1016/j.idcr.2024.e02136","DOIUrl":"10.1016/j.idcr.2024.e02136","url":null,"abstract":"<div><div>HIV infection frequently affects multiple systems, with hematological manifestations being the most prevalent. In some cases, cryptococcosis serves as the initial manifestation and a cause of infection involving HIV-positive patients. This case report describes a patient with thrombocytopenia who incidentally discovered <em>Cryptococcus</em> infiltrating the bone marrow upon bone marrow smear examination, highlighting that examining bone marrow is essential in diagnosing pancytopenia resulting from opportunistic fungal infections like cryptococcosis, especially in individuals with compromised immune systems.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02136"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142979803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergence of Coccidioides posadasii in an asymptomatic Ecuadorian patient with diabetes: A case report 厄瓜多尔无症状糖尿病患者出现波萨达球虫一例报告。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02137
Zanny Bastidas , Jeannete Zurita , Gabriela Sevillano , Jesus-Elias Dawaher , Pablo Cáceres , César Delgado
{"title":"Emergence of Coccidioides posadasii in an asymptomatic Ecuadorian patient with diabetes: A case report","authors":"Zanny Bastidas ,&nbsp;Jeannete Zurita ,&nbsp;Gabriela Sevillano ,&nbsp;Jesus-Elias Dawaher ,&nbsp;Pablo Cáceres ,&nbsp;César Delgado","doi":"10.1016/j.idcr.2024.e02137","DOIUrl":"10.1016/j.idcr.2024.e02137","url":null,"abstract":"<div><div>Coccidioidomycosis is a potentially serious but poorly studied mycosis in Ecuador. It is not a notifiable infection; therefore, its true incidence and prevalence in Ecuador remain unknown. Because primary lung disease due to coccidioidomycoses is typically self-limiting, it does not usually require treatment. Here, we present the first case of <em>Coccidioides posadasii</em> infection in an asymptomatic patient with diabetes without a history of travel to an endemic area. This is the first case reported in Ecuador in the last half-century.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02137"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of disseminated blastomycosis in New England
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02139
Cole Royer , Matthew Owens , Kenrick Wysong , Michael Madrid , Katrina Moreau
{"title":"A case of disseminated blastomycosis in New England","authors":"Cole Royer ,&nbsp;Matthew Owens ,&nbsp;Kenrick Wysong ,&nbsp;Michael Madrid ,&nbsp;Katrina Moreau","doi":"10.1016/j.idcr.2024.e02139","DOIUrl":"10.1016/j.idcr.2024.e02139","url":null,"abstract":"<div><div><em>Blastomyces</em> infections are classified as dimorphic fungal infections commonly seen geographically throughout the Mississippi and Ohio River Valleys, St. Laurence Seaways, as well as the Canadian providences of Ontario Manitoba, and Saskatchewan. Although primarily endemic in the Midwestern United States, there has been a rise in cases throughout New England. Factors that could contribute to this rise of blastomycosis include a changing climate, increasing use of immunosuppressive medications as well as a greater recognition of this disease. Initial presentation of blastomycosis follows the inhalation of fungal spores which can cause flu-like symptoms or mimic acute pneumonia. Blastomycosis can also present as a disseminated infection through extrapulmonary spread in both immunocompromised and immunocompetent hosts and cases present at similar rates within the population. Here we present a case of disseminated blastomycosis in a patient from New England with no reported pre-existing risk factors. The patient developed blastomycosis osteomyelitis in the left elbow which prompted surgical intervention as well as a 12-month regimen of voriconazole therapy. This case outlines the need to adopt better surveillance practices for blastomycosis in non-endemic areas as well as highlights the imperative role of healthcare staff in implementing proper reporting measures to track the spread of blastomycosis.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02139"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fatal case of sepsis caused by Raoultella ornithinolytica: A rare opportunistic pathogen
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02156
Rifah Anwar Assadi , Husain Abdulaziz AlAwadhi , Nageeb Hussein Abdulla Hasson , Rizah Anwar Assadi
{"title":"Fatal case of sepsis caused by Raoultella ornithinolytica: A rare opportunistic pathogen","authors":"Rifah Anwar Assadi ,&nbsp;Husain Abdulaziz AlAwadhi ,&nbsp;Nageeb Hussein Abdulla Hasson ,&nbsp;Rizah Anwar Assadi","doi":"10.1016/j.idcr.2025.e02156","DOIUrl":"10.1016/j.idcr.2025.e02156","url":null,"abstract":"<div><div>We present a rare case of sepsis caused by <em>Raoultella ornithinolytica</em>, a gram-negative, encapsulated bacterium. The patient, a 46-year-old male, was admitted to the intensive care unit with severe diabetic ketoacidosis, acute renal failure, and sepsis. Despite aggressive management, including continuous renal replacement therapy and high-dose inotropes, the patient's condition deteriorates rapidly, ultimately resulting in a fatal outcome. This case highlights the importance of considering <em>Raoultella ornithinolytica</em> in the differential diagnosis of sepsis, particularly in cases where the source of infection is unknown. The patient's clinical course underscores the challenges of managing sepsis in the intensive care unit and the need for continued research into the diagnosis, treatment, and prevention of sepsis caused by this rare opportunistic pathogen.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02156"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787684/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Necrotic erythema nodosum leprosum – A case of severe lepromatous reaction in a multibacillary leprosy patient
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02152
Hrithik Dakssesh Putta Nagarajan , Balakrishnan Kamaraj , Keerthivasan Selvanathan , Shubham Kumar , Shilpa Gaidhane , Sanjit Sah , Prakasini Satapathy , Rachana Mehta , Rodrigue Ndabashinze , Amogh Verma
{"title":"Necrotic erythema nodosum leprosum – A case of severe lepromatous reaction in a multibacillary leprosy patient","authors":"Hrithik Dakssesh Putta Nagarajan ,&nbsp;Balakrishnan Kamaraj ,&nbsp;Keerthivasan Selvanathan ,&nbsp;Shubham Kumar ,&nbsp;Shilpa Gaidhane ,&nbsp;Sanjit Sah ,&nbsp;Prakasini Satapathy ,&nbsp;Rachana Mehta ,&nbsp;Rodrigue Ndabashinze ,&nbsp;Amogh Verma","doi":"10.1016/j.idcr.2025.e02152","DOIUrl":"10.1016/j.idcr.2025.e02152","url":null,"abstract":"<div><div>Necrotic erythema nodosum leprosum (ENL) is an uncommon and severe complication of multibacillary leprosy, characterized by intense systemic inflammation, ulcerative lesions, and significant morbidity. This case report describes a 32-year-old male presenting with recurrent type 2 lepra reactions and necrotic lesions exacerbated by inconsistent adherence to multidrug therapy (MDT). The patient’s management involved MDT, corticosteroids, thalidomide, and hydroxychloroquine, which led to a substantial clinical improvement. Emerging evidence and a multidisciplinary approach have been used to address this complex pathophysiology and clinical presentation. This report demonstrates the necessity for uninterrupted treatment, early recognition, and tailored therapeutic interventions for managing severe lepra reactions.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02152"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute peritonitis secondary to spontaneous rupture of hepatic hydatid cyst: A case report and literature review
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02166
Imen Ben Ismail , Elmontassar Belleh Zaafouri, Hakim Zenaidi, Saber Rebii, Ayoub Zoghlami
{"title":"Acute peritonitis secondary to spontaneous rupture of hepatic hydatid cyst: A case report and literature review","authors":"Imen Ben Ismail ,&nbsp;Elmontassar Belleh Zaafouri,&nbsp;Hakim Zenaidi,&nbsp;Saber Rebii,&nbsp;Ayoub Zoghlami","doi":"10.1016/j.idcr.2025.e02166","DOIUrl":"10.1016/j.idcr.2025.e02166","url":null,"abstract":"<div><div>Spontaneous intraperitoneal rupture of hepatic hydatid cysts is a rare but serious complication that can lead to significant morbidity and mortality due to risks such as anaphylactic shock and secondary peritoneal hydatidosis. This report presents the case of a 59-year-old male farmer from a rural area of Tunisia who presented with severe abdominal pain, nausea, and vomiting. Diagnostic imaging revealed a large hepatic cyst with free peritoneal fluid, indicating a ruptured hydatid cyst. Emergency surgery involved cyst evacuation, peritoneal lavage, and drainage. Postoperatively, the patient developed a transient biliary fistula but recovered well with albendazole therapy to prevent recurrence. Six months post-surgery, the patient remains asymptomatic. The case underscores the importance of considering hydatid disease in acute abdomen diagnoses in endemic regions and highlights the critical role of imaging and timely surgical intervention. The literature review indicates variability in the prevalence of cyst rupture and emphasizes the need for a comprehensive approach combining surgery and antiparasitic treatment for effective management and recurrence prevention.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02166"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Babesiosis with low parasitemia as a cause of secondary hemophagocytic lymphohistiocytosis in a previously healthy adult
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02172
Max W. Jacobs , Joseph M. Rocco , Lisa K. Andersen , Thomas E. Robertson
{"title":"Babesiosis with low parasitemia as a cause of secondary hemophagocytic lymphohistiocytosis in a previously healthy adult","authors":"Max W. Jacobs ,&nbsp;Joseph M. Rocco ,&nbsp;Lisa K. Andersen ,&nbsp;Thomas E. Robertson","doi":"10.1016/j.idcr.2025.e02172","DOIUrl":"10.1016/j.idcr.2025.e02172","url":null,"abstract":"<div><div>The incidence of babesiosis is increasing and clinicians should have a high index of suspicion due to its diagnostic challenges and variable disease course, from asymptomatic infection to fulminant disease. We present a case of fatal secondary hemophagocytic lymphohistiocytosis (sHLH) due to acute babesiosis in a previously healthy adult. We also present a comprehensive review of previously reported sHLH cases triggered by babesiosis. Host factors, such as immunocompromising conditions or medications, appear to be a risk factor for developing sHLH while it is unclear if percent parasitemia of babesia correlates with development or outcomes of HLH. Increasing awareness to improve time to diagnosis is vital for treating both babesiosis and sHLH, while future studies should investigate the role for immunomodulator therapy in this setting.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02172"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Isolated tuberculoma involving multiple paranasal sinuses with aggressive features in an immunocompetent individual masquerading as a malignant neoplasm: A rarity unveiled with review of literature
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02179
Shaivy Malik , Rajat , Charanjeet Ahluwalia
{"title":"Isolated tuberculoma involving multiple paranasal sinuses with aggressive features in an immunocompetent individual masquerading as a malignant neoplasm: A rarity unveiled with review of literature","authors":"Shaivy Malik ,&nbsp;Rajat ,&nbsp;Charanjeet Ahluwalia","doi":"10.1016/j.idcr.2025.e02179","DOIUrl":"10.1016/j.idcr.2025.e02179","url":null,"abstract":"<div><div>Isolated primary tuberculoma of the paranasal sinuses is an exceedingly rare form of extra-pulmonary tuberculosis (EPTB), particularly in immunocompetent individuals. Its presentation is often atypical, mimicking aggressive neoplasms due to features such as local bone destruction, which complicates diagnosis and may lead to unnecessary invasive interventions. We report the case of a 32-year-old immunocompetent male presenting with chronic right nasal obstruction, rhinorrhoea, facial puffiness, hyposmia, and intermittent fever. Imaging revealed a heterogeneous mass in the right frontal, ethmoidal, and maxillary sinuses, with extensive bony erosion suggestive of a malignant etiology. Histopathological examination of biopsy tissue, however, demonstrated granulomatous inflammation with Langhans giant cells, necrosis, and acid-fast bacilli on Ziehl-Neelsen staining, confirming tuberculoma. Anti-tubercular treatment (ATT) was promptly initiated post-biopsy, leading to complete symptom resolution and no recurrence. This case sheds light on the importance of including tuberculoma in the differential diagnosis of aggressive sinonasal lesions in immunocompetent patients despite their rarity, and highlights the critical role of histopathology and ATT in effective management, potentially preventing extensive surgical resections and associated morbidity.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02179"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143386996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Black tongue caused by linezolid in children: One case report and literature review
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02181
Chunyu Zhang , Hongxia Shen , Jing Zhang , Lujie Xu , Meixing Yan , Chang Liu
{"title":"Black tongue caused by linezolid in children: One case report and literature review","authors":"Chunyu Zhang ,&nbsp;Hongxia Shen ,&nbsp;Jing Zhang ,&nbsp;Lujie Xu ,&nbsp;Meixing Yan ,&nbsp;Chang Liu","doi":"10.1016/j.idcr.2025.e02181","DOIUrl":"10.1016/j.idcr.2025.e02181","url":null,"abstract":"<div><div>Linezolid is commonly used to treat multidrug-resistant Gram-positive bacterial infections. Among children, the most common adverse reactions associated with linezolid administration encompass diarrhoea, vomiting, headache and thrombocytopenia. It is noted that tongue discoloration can occur with linezolid in the medication package insert. In this article, we present a case of a child with black tongue as a rare adverse reaction to linezolid and review of relevant literature.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02181"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143360429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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