IDCases最新文献_第2页

A case of disseminated blastomycosis in New England

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02139

Cole Royer , Matthew Owens , Kenrick Wysong , Michael Madrid , Katrina Moreau

{"title":"A case of disseminated blastomycosis in New England","authors":"Cole Royer , Matthew Owens , Kenrick Wysong , Michael Madrid , Katrina Moreau","doi":"10.1016/j.idcr.2024.e02139","DOIUrl":"10.1016/j.idcr.2024.e02139","url":null,"abstract":"<div><div><em>Blastomyces</em> infections are classified as dimorphic fungal infections commonly seen geographically throughout the Mississippi and Ohio River Valleys, St. Laurence Seaways, as well as the Canadian providences of Ontario Manitoba, and Saskatchewan. Although primarily endemic in the Midwestern United States, there has been a rise in cases throughout New England. Factors that could contribute to this rise of blastomycosis include a changing climate, increasing use of immunosuppressive medications as well as a greater recognition of this disease. Initial presentation of blastomycosis follows the inhalation of fungal spores which can cause flu-like symptoms or mimic acute pneumonia. Blastomycosis can also present as a disseminated infection through extrapulmonary spread in both immunocompromised and immunocompetent hosts and cases present at similar rates within the population. Here we present a case of disseminated blastomycosis in a patient from New England with no reported pre-existing risk factors. The patient developed blastomycosis osteomyelitis in the left elbow which prompted surgical intervention as well as a 12-month regimen of voriconazole therapy. This case outlines the need to adopt better surveillance practices for blastomycosis in non-endemic areas as well as highlights the imperative role of healthcare staff in implementing proper reporting measures to track the spread of blastomycosis.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02139"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11750486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143025290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fatal case of sepsis caused by Raoultella ornithinolytica: A rare opportunistic pathogen

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02156

Rifah Anwar Assadi , Husain Abdulaziz AlAwadhi , Nageeb Hussein Abdulla Hasson , Rizah Anwar Assadi

引用次数: 0

Necrotic erythema nodosum leprosum – A case of severe lepromatous reaction in a multibacillary leprosy patient

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02152

Hrithik Dakssesh Putta Nagarajan , Balakrishnan Kamaraj , Keerthivasan Selvanathan , Shubham Kumar , Shilpa Gaidhane , Sanjit Sah , Prakasini Satapathy , Rachana Mehta , Rodrigue Ndabashinze , Amogh Verma

引用次数: 0

Acute peritonitis secondary to spontaneous rupture of hepatic hydatid cyst: A case report and literature review

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02166

Imen Ben Ismail , Elmontassar Belleh Zaafouri, Hakim Zenaidi, Saber Rebii, Ayoub Zoghlami

{"title":"Acute peritonitis secondary to spontaneous rupture of hepatic hydatid cyst: A case report and literature review","authors":"Imen Ben Ismail , Elmontassar Belleh Zaafouri, Hakim Zenaidi, Saber Rebii, Ayoub Zoghlami","doi":"10.1016/j.idcr.2025.e02166","DOIUrl":"10.1016/j.idcr.2025.e02166","url":null,"abstract":"<div><div>Spontaneous intraperitoneal rupture of hepatic hydatid cysts is a rare but serious complication that can lead to significant morbidity and mortality due to risks such as anaphylactic shock and secondary peritoneal hydatidosis. This report presents the case of a 59-year-old male farmer from a rural area of Tunisia who presented with severe abdominal pain, nausea, and vomiting. Diagnostic imaging revealed a large hepatic cyst with free peritoneal fluid, indicating a ruptured hydatid cyst. Emergency surgery involved cyst evacuation, peritoneal lavage, and drainage. Postoperatively, the patient developed a transient biliary fistula but recovered well with albendazole therapy to prevent recurrence. Six months post-surgery, the patient remains asymptomatic. The case underscores the importance of considering hydatid disease in acute abdomen diagnoses in endemic regions and highlights the critical role of imaging and timely surgical intervention. The literature review indicates variability in the prevalence of cyst rupture and emphasizes the need for a comprehensive approach combining surgery and antiparasitic treatment for effective management and recurrence prevention.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02166"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Babesiosis with low parasitemia as a cause of secondary hemophagocytic lymphohistiocytosis in a previously healthy adult

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02172

Max W. Jacobs , Joseph M. Rocco , Lisa K. Andersen , Thomas E. Robertson

引用次数: 0

Isolated tuberculoma involving multiple paranasal sinuses with aggressive features in an immunocompetent individual masquerading as a malignant neoplasm: A rarity unveiled with review of literature

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02179

Shaivy Malik , Rajat , Charanjeet Ahluwalia

{"title":"Isolated tuberculoma involving multiple paranasal sinuses with aggressive features in an immunocompetent individual masquerading as a malignant neoplasm: A rarity unveiled with review of literature","authors":"Shaivy Malik , Rajat , Charanjeet Ahluwalia","doi":"10.1016/j.idcr.2025.e02179","DOIUrl":"10.1016/j.idcr.2025.e02179","url":null,"abstract":"<div><div>Isolated primary tuberculoma of the paranasal sinuses is an exceedingly rare form of extra-pulmonary tuberculosis (EPTB), particularly in immunocompetent individuals. Its presentation is often atypical, mimicking aggressive neoplasms due to features such as local bone destruction, which complicates diagnosis and may lead to unnecessary invasive interventions. We report the case of a 32-year-old immunocompetent male presenting with chronic right nasal obstruction, rhinorrhoea, facial puffiness, hyposmia, and intermittent fever. Imaging revealed a heterogeneous mass in the right frontal, ethmoidal, and maxillary sinuses, with extensive bony erosion suggestive of a malignant etiology. Histopathological examination of biopsy tissue, however, demonstrated granulomatous inflammation with Langhans giant cells, necrosis, and acid-fast bacilli on Ziehl-Neelsen staining, confirming tuberculoma. Anti-tubercular treatment (ATT) was promptly initiated post-biopsy, leading to complete symptom resolution and no recurrence. This case sheds light on the importance of including tuberculoma in the differential diagnosis of aggressive sinonasal lesions in immunocompetent patients despite their rarity, and highlights the critical role of histopathology and ATT in effective management, potentially preventing extensive surgical resections and associated morbidity.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02179"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143386996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Black tongue caused by linezolid in children: One case report and literature review

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02181

Chunyu Zhang , Hongxia Shen , Jing Zhang , Lujie Xu , Meixing Yan , Chang Liu

引用次数: 0

Tropheryma whipplei infection presenting as indolent endophthalmitis

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02178

Rami Waked , Jeffrey K. Moore , Brandon Winward , Sophia Ham , Howard W. Hoyt , Leyla Azis

{"title":"Tropheryma whipplei infection presenting as indolent endophthalmitis","authors":"Rami Waked , Jeffrey K. Moore , Brandon Winward , Sophia Ham , Howard W. Hoyt , Leyla Azis","doi":"10.1016/j.idcr.2025.e02178","DOIUrl":"10.1016/j.idcr.2025.e02178","url":null,"abstract":"<div><div><em>Tropheryma whipplei</em> (<em>T. whipplei</em>) infection can be difficult to diagnose due to its variable clinical manifestations and the limitations of standard diagnostic tests. This case describes a 78-year-old male with blurry vision and floaters in his right eye five months after cataract surgery, along with new onset weight loss and arthralgias. Ophthalmologic examination revealed inflammation and posterior vitritis, and vitreous biopsy identified <em>T. whipplei</em> via broad-range bacterial PCR, despite negative vitreous cultures and unremarkable flow cytometry. Gastrointestinal endoscopic and cerebrospinal fluid studies revealed no pathological or molecular evidence of the disease, complicating the diagnosis. Treatment with intravenous ceftriaxone followed by oral trimethoprim-sulfamethoxazole for 12 months resulted in resolution of symptoms and inflammation, with normalization of laboratory markers. This case underscores the diagnostic utility of broad-range bacterial PCR in atypical infections and highlights Whipple infection as a differential diagnosis in ocular presentations. Comprehensive interdisciplinary evaluation was critical for effective management.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02178"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143360430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tuberculous pericarditis in a 71-year-old immunocompetent patient: Case report 一名 71 岁免疫功能正常患者的结核性心包炎：病例报告。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02122

Carlos Mejia Irias , Odalis Cerrato , Estephany Díaz Mairena

{"title":"Tuberculous pericarditis in a 71-year-old immunocompetent patient: Case report","authors":"Carlos Mejia Irias , Odalis Cerrato , Estephany Díaz Mairena","doi":"10.1016/j.idcr.2024.e02122","DOIUrl":"10.1016/j.idcr.2024.e02122","url":null,"abstract":"<div><div>Tuberculosis is a transmissible disease caused by the bacterium <em>Mycobacterium tuberculosis</em>. It is the leading cause of mortality due to infectious diseases. Tuberculous pericarditis is one of the manifestations of extrapulmonary tuberculosis and represents the primary cause of pericardial effusion in developing countries. We present the case of a 71-year-old male patient with a history of 1 month of dyspnea, accompanied by paroxysmal nocturnal dyspnea and unintentional weight loss. An echocardiogram revealed the presence of severe pericardial effusion, for which pericardiocentesis was performed, and the pericardial fluid was analyzed using the Xpert MTB/RIF test, which confirmed the presence of <em>Mycobacterium tuberculosis</em> without resistance to Rifampicin. This is a case of Tuberculous Pericarditis as the cause of pericardial effusion, in which the etiological diagnosis was made possible through molecular biological analysis of the pericardial fluid. The importance of disseminating such cases lies in emphasizing that, even in the 21st century, in developing countries like Honduras, it is crucial not to dismiss tuberculosis infection, as it remains the leading cause of pericardial effusion in endemic regions.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02122"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11664178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142883320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe dual fungal infection after bispecific antibody therapy: A case of invasive aspergillosis and mucormycosis in immunocompromised patient 双特异性抗体治疗后严重双重真菌感染：免疫功能低下患者侵袭性曲霉病和毛霉病1例。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02140

Sarah Sakalihasan , Frédéric Lifrange , Mathieu Czajkowski , Veronique Goncette , Bernard Duysinx , Pierre Lovinfosse , Damla Can , Raphael Schils , Marie-Pierre Hayette , Adrien De Voeght

{"title":"Severe dual fungal infection after bispecific antibody therapy: A case of invasive aspergillosis and mucormycosis in immunocompromised patient","authors":"Sarah Sakalihasan , Frédéric Lifrange , Mathieu Czajkowski , Veronique Goncette , Bernard Duysinx , Pierre Lovinfosse , Damla Can , Raphael Schils , Marie-Pierre Hayette , Adrien De Voeght","doi":"10.1016/j.idcr.2024.e02140","DOIUrl":"10.1016/j.idcr.2024.e02140","url":null,"abstract":"<div><div>Bispecific antibody is a new treatment for hematological disease, especially for lymphoma, myeloma and acute lymphoblastic leukemia. This class of treatment presents the same kind of side effect as CAR-T cell which are immune-mediated. Nevertheless, infectious complication remains a major concerns with related mortality. Fungal infection are rarely reported in clinical trial but remains a major concern. We report a case of a co-infection of <em>Aspergillus</em> and <em>Mucorales</em> in a patient with diffuse large B-cell lymphoma (DLBCL) following treatment with the bispecific antibody epcoritamab. The patient developed severe cytokine release syndrome (CRS) and subsequent fungal infections, which were challenging to diagnose and treat due to the complexities of managing immunocompromised patients and co-infection. Advanced diagnostics, including PET-CT, and a combination of antifungal therapies were crucial in achieving remission. The case underscores the need for early diagnosis, multidisciplinary management, and innovative treatment strategies in similar high-risk patients.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02140"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0