Kevin Kurator , Leona Mason , David Bruckner , Hongying Tan , Glenn Mathisen
{"title":"诊断囊异孢子虫病的患者与艾滋病毒和适度降低CD4计数","authors":"Kevin Kurator , Leona Mason , David Bruckner , Hongying Tan , Glenn Mathisen","doi":"10.1016/j.idcr.2025.e02259","DOIUrl":null,"url":null,"abstract":"<div><div>Cystoisosporiasis is caused by a coccidian parasite that is found worldwide and can cause diarrheal illness. It is more common in the immunocompromised, in whom it can cause extended and severe disease courses. Diagnosis is not always straightforward as oocytes are not always present in routine stool samples, but it is possible to visualize the organism with specialized staining techniques as well as within enterocytes on intestinal biopsies. We present a case in which this mode of diagnosis was crucial for determining the cause of diarrhea in a patient with HIV and CD4 count above 200 cells/mm<sup>3</sup>.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02259"},"PeriodicalIF":1.1000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diagnosis of cystoisosporiasis in a patient with HIV and modestly decreased CD4 counts\",\"authors\":\"Kevin Kurator , Leona Mason , David Bruckner , Hongying Tan , Glenn Mathisen\",\"doi\":\"10.1016/j.idcr.2025.e02259\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Cystoisosporiasis is caused by a coccidian parasite that is found worldwide and can cause diarrheal illness. It is more common in the immunocompromised, in whom it can cause extended and severe disease courses. Diagnosis is not always straightforward as oocytes are not always present in routine stool samples, but it is possible to visualize the organism with specialized staining techniques as well as within enterocytes on intestinal biopsies. We present a case in which this mode of diagnosis was crucial for determining the cause of diarrhea in a patient with HIV and CD4 count above 200 cells/mm<sup>3</sup>.</div></div>\",\"PeriodicalId\":47045,\"journal\":{\"name\":\"IDCases\",\"volume\":\"40 \",\"pages\":\"Article e02259\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IDCases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214250925001155\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IDCases","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214250925001155","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Diagnosis of cystoisosporiasis in a patient with HIV and modestly decreased CD4 counts
Cystoisosporiasis is caused by a coccidian parasite that is found worldwide and can cause diarrheal illness. It is more common in the immunocompromised, in whom it can cause extended and severe disease courses. Diagnosis is not always straightforward as oocytes are not always present in routine stool samples, but it is possible to visualize the organism with specialized staining techniques as well as within enterocytes on intestinal biopsies. We present a case in which this mode of diagnosis was crucial for determining the cause of diarrhea in a patient with HIV and CD4 count above 200 cells/mm3.
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