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Influenza A Virus Complicated by Myopericarditis with Pericardial Effusion
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02158
Dhara Rana , Anson Marsh , Mahum Sami , Hiral Shukla , Dimitris Barbouletos , Nicholas Calder
{"title":"Influenza A Virus Complicated by Myopericarditis with Pericardial Effusion","authors":"Dhara Rana ,&nbsp;Anson Marsh ,&nbsp;Mahum Sami ,&nbsp;Hiral Shukla ,&nbsp;Dimitris Barbouletos ,&nbsp;Nicholas Calder","doi":"10.1016/j.idcr.2025.e02158","DOIUrl":"10.1016/j.idcr.2025.e02158","url":null,"abstract":"<div><div>Influenza A viral infection classically presents as pulmonary manifestations which often require symptomatic management. It can rarely be complicated by pericarditis with concurrent pericardial effusion. We present a unique case of myopericarditis with a pericardial effusion caused by Influenza A. Our patient was presented with elevated troponin and BNP. Chest x-ray showed an enlargement of the cardiac silhouette and clear lungs. CT angiography was remarkable for pericardial effusion. An echocardiogram was performed which demonstrated mild concentric left ventricular hypertrophy with small to moderate circumferential pericardial effusion, and no echocardiographic signs of cardiac tamponade. The significance of our case makes clinicians aware that acute myopericarditis with concurrent pericardial effusion can lead to fatal complications such as cardiac tamponade or cardiogenic shock if left untreated. Early diagnosis and treatment as presented in our case could reduce the risk of such severe cardiac events from occurring.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02158"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786201/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of ehrlichiosis with meningoencephalitis and multi-organ failure
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02165
Neaam Al-Bahadili, Ibrahim Shamasneh, Chinelo Meniru, Zola Nlandu
{"title":"A case of ehrlichiosis with meningoencephalitis and multi-organ failure","authors":"Neaam Al-Bahadili,&nbsp;Ibrahim Shamasneh,&nbsp;Chinelo Meniru,&nbsp;Zola Nlandu","doi":"10.1016/j.idcr.2025.e02165","DOIUrl":"10.1016/j.idcr.2025.e02165","url":null,"abstract":"<div><div>Ehrlichiosis is a bacterial illness primarily transmitted through the bite of an infected lone star tick. According to the Centers for Disease Control (CDC), the United States is experiencing a rising number of reported cases, with a case fatality rate of approximately 1 %. The disease typically manifests as a non-specific flu-like illness, however in rare cases, it can progress to severe disease with multi-organ failure and mortality. We present a case of a 70-year-old male who was transferred to the intensive care unit of our facility for the management of septic shock associated with multi-organ failure. He had a history of recent exposure to multiple tick-bites while performing yard work. He was diagnosed with Ehrlichiosis based on positive serum IgM and IgG antibodies against Ehrlichia chaffeenesis. A lumbar puncture also confirmed meningoencephalitis. The patient completed intravenous Doxycycline treatment for 14 days, resulting in clinical improvement. Identifying Ehrlichia as the causal organism for meningoencephalitis and severe disease is challenging due to its low prevalence. This case emphasizes the significance of promptly suspecting and identifying ehrlichiosis in patients who exhibit meningoencephalitis symptoms or end-organ failure and have a recent history of engaging in outdoor activities with a risk of exposure to ticks, especially in endemic regions. It also signifies the importance of empirically treating with doxycycline even before its diagnosis as delay in providing doxycycline can significantly lead to more complications compared with patients who receive it early on during hospital admission.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02165"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Septic shock caused by emphysematous hepatitis complicated with intracranial infection
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02159
Miao Chen , Jianbo Chen , Zhengzhi Zhuang , Xiaojun He , Yue Wang , Junwen Liang , Runpei Lin , Gengxin Cai
{"title":"Septic shock caused by emphysematous hepatitis complicated with intracranial infection","authors":"Miao Chen ,&nbsp;Jianbo Chen ,&nbsp;Zhengzhi Zhuang ,&nbsp;Xiaojun He ,&nbsp;Yue Wang ,&nbsp;Junwen Liang ,&nbsp;Runpei Lin ,&nbsp;Gengxin Cai","doi":"10.1016/j.idcr.2025.e02159","DOIUrl":"10.1016/j.idcr.2025.e02159","url":null,"abstract":"<div><h3>Purpose</h3><div>Emphysematous hepatitis is an uncommon and life-threatening hepatic infection, characterized by the presence of gas within the liver and high mortality. There are few reports of this condition.</div></div><div><h3>Method</h3><div>We report a case of septic shock caused by emphysematous hepatitis complicated with intracranial infection, and review the current literature on emphysematous hepatitis.</div></div><div><h3>Results</h3><div>A 57-year-old male with uncontrolled diabetes mellitus developed emphysematous hepatitis complicated with intracranial infection, which progressed to septic shock. The patient was treated with antibiotics and received percutaneous liver puncture drainage early and was discharged preferably in remission. From the literature review, we found 16 previously published cases of emphysematous hepatitis.</div></div><div><h3>Conclusion</h3><div>Given our experience and the literature review, percutaneous liver puncture drainage or surgical treatment in the early stage may be beneficial to patients with emphysematous hepatitis.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02159"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143341018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of infertility diagnosed with tuberculous endometritis
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02154
Yukiko Fukui-Watanabe , Mai Suzuki , Asako Ochiai , Karin Ashizawa , Harumi Saeki , Toshio Naito
{"title":"A case of infertility diagnosed with tuberculous endometritis","authors":"Yukiko Fukui-Watanabe ,&nbsp;Mai Suzuki ,&nbsp;Asako Ochiai ,&nbsp;Karin Ashizawa ,&nbsp;Harumi Saeki ,&nbsp;Toshio Naito","doi":"10.1016/j.idcr.2025.e02154","DOIUrl":"10.1016/j.idcr.2025.e02154","url":null,"abstract":"<div><div>A 30-year-old woman presented with infertility and irregular menstruation. Physical examination revealed obesity and slightly pale conjunctivae. Transvaginal ultrasound revealed polycystic ovary, bilateral hydrosalpinx, and endometrial thickening. Magnetic resonance imaging of the pelvis showed several large cystic lesions and elongated fallopian tubes. An endometrial biopsy was performed to investigate the endometrial thickening. Pathological findings included small non-caseating epithelioid cell granulomas with scattered plasma cell infiltration. The microbiological analysis of the endometrial biopsy sample showed a negative result for Ziehl–Neelsen staining; however, after four weeks, the Mycobacterium culture was positive for <em>Mycobacterium tuberculosis</em>. Thus, a definitive diagnosis of tuberculous endometritis was made. The patient was effectively treated with the standard treatment comprising isoniazid, rifampicin, ethambutol, and pyrazinamide for 6 months.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02154"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare encounter: Fusarium falciformis and the challenges of ocular infection in the context of biologic therapy
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02144
Kelly Larimore , Claudia R. Libertin
{"title":"A rare encounter: Fusarium falciformis and the challenges of ocular infection in the context of biologic therapy","authors":"Kelly Larimore ,&nbsp;Claudia R. Libertin","doi":"10.1016/j.idcr.2024.e02144","DOIUrl":"10.1016/j.idcr.2024.e02144","url":null,"abstract":"<div><div>This case report presents a patient with exogenous endophthalmitis caused by <em>Fusarium falciformis</em>, highlighting the risks associated with immunosuppressive therapy using Adalimumab for rheumatoid arthritis. The patient's compromised immune system, likely exacerbated by gardening exposure, facilitated the fungal infection, marking the first documented instance of <em>Fusarium</em>-related endophthalmitis linked to Adalimumab. <em>Fusarium</em> species are prevalent in the environment but are infrequently recognized as pathogens in humans, particularly in immunocompromised individuals. The differentiation between infectious and non-infectious ocular inflammation poses a significant challenge for clinicians. In this case, early involvement of ophthalmology was critical, leading to effective treatment strategies. Notably, in vitro testing revealed unexpected sensitivity of the isolated <em>Fusarium</em> strain to amphotericin B, which, combined with posaconazole, proved beneficial when combined with intravitreal injections of amphotericin B. This underscores the importance of tailored therapeutic approaches for rare ocular fungal infections and the necessity for increased awareness among healthcare providers regarding potential ocular adverse effects of biologic therapies. Ultimately, this case serves as a vital reminder of the complexities in managing ocular infections in patients receiving immunomodulatory treatments, advocating for vigilant assessment and prompt intervention to preserve vision.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02144"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An unusual case of varicella zoster encephalitis mimicking a glioblastoma on magnetic resonance imaging and magnetic resonance spectroscopy 一个不寻常的水痘带状疱疹脑炎模拟胶质母细胞瘤的磁共振成像和磁共振波谱。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02124
Brenden Nago , Jeffrey E. Liu
{"title":"An unusual case of varicella zoster encephalitis mimicking a glioblastoma on magnetic resonance imaging and magnetic resonance spectroscopy","authors":"Brenden Nago ,&nbsp;Jeffrey E. Liu","doi":"10.1016/j.idcr.2024.e02124","DOIUrl":"10.1016/j.idcr.2024.e02124","url":null,"abstract":"<div><div>The authors report a case of varicella zoster encephalitis, mimicking a glioblastoma on Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS). The limitations of MRI/MRS, may lead to delayed treatment with antiviral agents, which can result in increased morbidity and mortality. The possibility of viral encephalitis should remain in the differential diagnosis of all patients presenting with headaches and confusion, even when imaging results are indicative of a neoplastic process.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02124"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11667170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rare case of Gardnerella vaginalis spondylodiscitis 罕见的阴道加德纳菌性脊柱炎1例。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02126
Alex Belote, Kassem Hammoud
{"title":"A rare case of Gardnerella vaginalis spondylodiscitis","authors":"Alex Belote,&nbsp;Kassem Hammoud","doi":"10.1016/j.idcr.2024.e02126","DOIUrl":"10.1016/j.idcr.2024.e02126","url":null,"abstract":"<div><div>A 55-year-old-male with a chronic left uretero-pelvic junction (UPJ) obstruction managed with intermittent stent exchanges presented with low midline back pain. CT Abdomen/Pelvis revealed spondylodiscitis at L4-L5, further demonstrated on MRI Lumbar spine. Imaging also revealed the left nephro-ureteral stent was mispositioned, with some mild wall thickening of the left ureter. He was not systemically ill, and antimicrobials were held. He underwent a L4/5 disc biopsy, and pathology revealed acute discitis. Blood and biopsy cultures remained negative through hospital day 5. He then underwent repeat L4/5 disc biopsy. Cultures of repeat biopsy resulted in <em>Gardnerella vaginalis</em>. IV antimicrobials were stopped, and oral Metronidazole was started. He completed 10 weeks of Metronidazole therapy, with significant clinical improvement.</div><div><em>G. vaginalis</em> is a rare cause of bone and joint infections. It is difficult to culture and is less virulent than common bacteria associated with native vertebral osteomyelitis. There have been few case reports of <em>G. vaginalis</em> osteomyelitis or prosthetic joint infection, especially in males. <em>G. vaginalis</em> can rarely colonize the urethra in men and has been known to form biofilm on foreign material in the female genitourinary system. We suspect our patient had developed colonization of his ureteral stent, predisposing him to osteomyelitis. Were repeat biopsy not pursued in this case, our patient likely could have developed empiric treatment failure. Holding antibiotics after initial biopsy proved highly beneficial.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02126"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11699804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges 揭露结核性关节炎在假体关节:诊断和治疗的挑战。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02134
Asbah Rahman, Aastha Randhawa, Yu Shia Lin
{"title":"Unmasking tuberculous arthritis in a prosthetic joint: Diagnostic and therapeutic challenges","authors":"Asbah Rahman,&nbsp;Aastha Randhawa,&nbsp;Yu Shia Lin","doi":"10.1016/j.idcr.2024.e02134","DOIUrl":"10.1016/j.idcr.2024.e02134","url":null,"abstract":"<div><div>An 85-year-old woman with a history of total knee replacements for osteoarthritis in the past, presented with left knee swelling and pain that persisted for 14 months. An initial diagnosis of synovial cyst was made, and she underwent multiple aspirations and symptomatic treatments without improvement. Repeat arthrocentesis showed a WBC of 56,000/μL with 61 % neutrophils and 34 % lymphocytes. Synovial fluid bacterial and fungal cultures were negative. The acid-fast bacilli (AFB) culture revealed the Mycobacterium tuberculosis complex and was confirmed by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) Mass Spectrometry. This case highlights the challenges of diagnosing tuberculous prosthetic joint infection in an elderly individual with knee pain.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02134"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11722171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis of disseminated cryptococcosis via iliac bone marrow aspirate analysis 髂骨髓抽吸分析诊断播散性隐球菌病。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02136
Weibu Chen, Xueyan Chen
{"title":"Diagnosis of disseminated cryptococcosis via iliac bone marrow aspirate analysis","authors":"Weibu Chen,&nbsp;Xueyan Chen","doi":"10.1016/j.idcr.2024.e02136","DOIUrl":"10.1016/j.idcr.2024.e02136","url":null,"abstract":"<div><div>HIV infection frequently affects multiple systems, with hematological manifestations being the most prevalent. In some cases, cryptococcosis serves as the initial manifestation and a cause of infection involving HIV-positive patients. This case report describes a patient with thrombocytopenia who incidentally discovered <em>Cryptococcus</em> infiltrating the bone marrow upon bone marrow smear examination, highlighting that examining bone marrow is essential in diagnosing pancytopenia resulting from opportunistic fungal infections like cryptococcosis, especially in individuals with compromised immune systems.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02136"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142979803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emergence of Coccidioides posadasii in an asymptomatic Ecuadorian patient with diabetes: A case report 厄瓜多尔无症状糖尿病患者出现波萨达球虫一例报告。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02137
Zanny Bastidas , Jeannete Zurita , Gabriela Sevillano , Jesus-Elias Dawaher , Pablo Cáceres , César Delgado
{"title":"Emergence of Coccidioides posadasii in an asymptomatic Ecuadorian patient with diabetes: A case report","authors":"Zanny Bastidas ,&nbsp;Jeannete Zurita ,&nbsp;Gabriela Sevillano ,&nbsp;Jesus-Elias Dawaher ,&nbsp;Pablo Cáceres ,&nbsp;César Delgado","doi":"10.1016/j.idcr.2024.e02137","DOIUrl":"10.1016/j.idcr.2024.e02137","url":null,"abstract":"<div><div>Coccidioidomycosis is a potentially serious but poorly studied mycosis in Ecuador. It is not a notifiable infection; therefore, its true incidence and prevalence in Ecuador remain unknown. Because primary lung disease due to coccidioidomycoses is typically self-limiting, it does not usually require treatment. Here, we present the first case of <em>Coccidioides posadasii</em> infection in an asymptomatic patient with diabetes without a history of travel to an endemic area. This is the first case reported in Ecuador in the last half-century.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02137"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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