IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2024.e02131
Sirine Ahmad , Mohammed Alsaeed
{"title":"An uncommon cause of osteomyelitis: Serratia fonticola A rare pathogen in human infections","authors":"Sirine Ahmad , Mohammed Alsaeed","doi":"10.1016/j.idcr.2024.e02131","DOIUrl":"10.1016/j.idcr.2024.e02131","url":null,"abstract":"<div><div>Osteomyelitis is a prevalent orthopedic condition. The most frequently associated pathogens are <em>Staphylococcus aureus</em>, coagulase-negative Staphylococci, and aerobic gram-negative bacilli. The treatment includes the administration of antibiotics targeting the pathogens and possible surgical debridement. Although <em>Serratia fonticola</em> has been isolated in various tissues, including the respiratory, gastrointestinal, urinary, and biliary tracts, as well as in wounds, human infections associated with <em>S. fonticola</em> have rarely been reported. Here, we present an uncommon case of osteomyelitis secondary to <em>S. fonticola</em> infection.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02131"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11722193/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142972582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From cradle to late life: Chicken pox in a sixty-one year old man","authors":"Milad Shemshadi , Lotfollah Davoodi , Amirmasoud Taheri","doi":"10.1016/j.idcr.2025.e02153","DOIUrl":"10.1016/j.idcr.2025.e02153","url":null,"abstract":"<div><h3>Objective</h3><div>This case report aims to highlight the rare occurrence of varicella infection in an elderly individual and emphasize the importance of early diagnosis and prompt treatment to prevent complications.</div></div><div><h3>Method</h3><div>A 61-year-old man with papulovesicular and pustular lesions was diagnosed with varicella based on his medical history and physical examination findings. He received valacyclovir and was instructed to avoid contact with unvaccinated individuals.</div></div><div><h3>Result</h3><div>The patient reported significant improvement after a week of treatment with valacyclovir, and the vesicles had begun to dehydrate without any new lesions.</div></div><div><h3>Conclusion</h3><div>While chickenpox is more common in children, adults can still be susceptible to the virus, especially in countries where vaccination efforts have not been thoroughly implemented. The case highlights the importance of promoting vaccination and public health initiatives to prevent the spread of infectious diseases and prompt diagnosis and treatment to reduce the risk of complications.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02153"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11787590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02224
Harris T. Feldman , Matthew Neale , Ajay Batra , Mark Mangano , Michael C. Newstein
{"title":"A rare case of acute liver failure due to disseminated Varicella-Zoster Virus (VZV) infection","authors":"Harris T. Feldman , Matthew Neale , Ajay Batra , Mark Mangano , Michael C. Newstein","doi":"10.1016/j.idcr.2025.e02224","DOIUrl":"10.1016/j.idcr.2025.e02224","url":null,"abstract":"<div><div>Varicella zoster virus (VZV) is a human alpha herpes virus that typically manifests in humans with two distinct cutaneous phenotypes: primary varicella, or chickenpox, and secondary reactivation, or Shingles, after establishing latency in the cranial and dorsal root ganglia. VZV infection can present with rarer manifestations including encephalitis, pneumonia, hepatitis, myocarditis, and nephritis. Immunocompromised populations are at the greatest risk for cutaneous and visceral dissemination. The progression of VZV hepatitis to acute liver failure is exceedingly rare, with very few published cases in the literature. In the following case, we report the initial presentation and clinical manifestations of an immunocompromised patient who presented with vesicular skin findings and elevated transaminases, who quickly progressed to acute liver failure, and had postmortem findings of disseminated VZV infection.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02224"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143833683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02189
J. Zintgraff , M. Peña , V. Di Matteo , R. Astesana , A. Fernández Garcés , G. Astudillo
{"title":"Unusual findings in diarrheal disease: Detection of a microscopic entity of unclear significance","authors":"J. Zintgraff , M. Peña , V. Di Matteo , R. Astesana , A. Fernández Garcés , G. Astudillo","doi":"10.1016/j.idcr.2025.e02189","DOIUrl":"10.1016/j.idcr.2025.e02189","url":null,"abstract":"<div><div>A 70-year-old woman presented with abdominal pain and diarrhea, with negative stool tests for common pathogens. Microscopy revealed a unique round structure with hyaline pseudopod-like extensions and a double membrane. While literature suggests a potential link to Urbanorum, a debated entity first reported in the 1990s, its classification remains uncertain. This case highlights the importance of rigorous methodologies to establish the clinical significance of such findings.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02189"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143535131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02163
Makram Tbini , Chaima Ben Ammar , Ines Riahi , Mabrouk Chamakh , Mamia Ben Salah
{"title":"Otomyiasis caused by Lucilia Sericata: A case report","authors":"Makram Tbini , Chaima Ben Ammar , Ines Riahi , Mabrouk Chamakh , Mamia Ben Salah","doi":"10.1016/j.idcr.2025.e02163","DOIUrl":"10.1016/j.idcr.2025.e02163","url":null,"abstract":"<div><div>Otomysis is the infestation of human ears with dipterous larvae. It is a rare medical issue, primarily observed in individuals with underlying vulnerabilities residing in tropical and subtropical regions.</div><div>A 56-year-old farmer, with a history of chronic otitis media, presented to our emergency department for otalgia and pruritus of the right ear. Otoscopic examination revealed numerous whitish larvae. Management was based on abundant irrigation using saline solution</div><div>Otomyiasis is a rare disease that should be considered in the differential diagnosis of patients presenting with unexplained otological symptoms, particularly in rural areas.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02163"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143550857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A case report of discordant Chikungunya manifestations in a married couple: From acute undifferentiated fever to fatal sepsis with purpura fulminans","authors":"Ditthawat Pathomchareansukchai , Navin Horthongkham , Pinyo Rattanaumpawan","doi":"10.1016/j.idcr.2025.e02182","DOIUrl":"10.1016/j.idcr.2025.e02182","url":null,"abstract":"<div><div>Chikungunya virus, an alphavirus transmitted by mosquitoes, causes chikungunya fever, a non-fatal febrile illness characterized by severe arthralgia and rash. We are reporting on two Chikungunya cases who recently returned from the Thailand-Cambodia border. The first case involved a man who presented with atypical manifestations, including purpura fulminans and multi-organ failure, ultimately leading to death. Conversely, the subsequent case pertains to the spouse of the deceased, who exhibited typical symptoms.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02182"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143360097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02146
Ashlyn Lipnicky , Praveen Subramanian , Wissam El Atrouni
{"title":"A case of W. chitiniclastica bacteremia in a 38-year-old homeless male originating from a maggot-infested amputated foot","authors":"Ashlyn Lipnicky , Praveen Subramanian , Wissam El Atrouni","doi":"10.1016/j.idcr.2025.e02146","DOIUrl":"10.1016/j.idcr.2025.e02146","url":null,"abstract":"<div><div><em>Wohlfahrtiimonas</em> (<em>W.</em>) <em>chitiniclastica</em> was first isolated from the larval stage of the fly vector <em>Wohlfahrtia magnifica.</em> It is a gram-negative, non-motile, strictly aerobic rod that thrives in temperatures between 28º C and 37º C. Its strong chitinase activity aids in metamorphosis, which suggests a symbiotic relationship with the fly. Although rare, <em>W. chitiniclastica</em> has been implicated in human infections, like bacteremia and osteomyelitis, typically transmitted through fly larvae in skin wounds. Over the past decade, there have been 12 documented human infections, including five confirmed cases of bacteremia. We present a case involving a 38-year-old homeless male with <em>W. chitiniclastica</em> bacteremia secondary to maggot-infested wounds. The patient had a medical history of late latent syphilis and previous frostbite requiring right transmetatarsal amputation and presented with a stump infection on the right foot, featuring maggots. He was afebrile with stable signs and blood cultures revealed <em>W. chitiniclastica</em>. The pathogen was susceptible to various antibiotics, including cefepime, piperacillin/tazobactam, meropenem, trimethoprim-sulfamethoxazole, and levofloxacin. The patient was treated with piperacillin/tazobactam and later transitioned to oral trimethoprim-sulfamethoxazole but left against medical advice. This case underscores the intersection of infectious diseases and social inequalities, highlighting the need for clinicians to consider <em>W. chitiniclastica</em> in patients with poor hygiene, alcoholism, peripheral vascular disease, and open wounds. It also emphasizes the dual role of maggots in wound care, capable of both cleaning necrotic tissue and introducing pathogenic bacteria.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02146"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2024.e02130
H. Shatikkulamin , Chandana Shajil
{"title":"Acute gonococcal urethritis","authors":"H. Shatikkulamin , Chandana Shajil","doi":"10.1016/j.idcr.2024.e02130","DOIUrl":"10.1016/j.idcr.2024.e02130","url":null,"abstract":"<div><div>Gonococcal urethritis is a sexually transmitted infection caused by obligate gram-negative diplococci, Neisseria gonorrhoeae. In a patient complaining of dysuria and urethral discharge, the diagnosis is typically confirmed by identifying the bacteria in mucosal secretions. Inadequately treated or untreated cases are at a risk of developing epididymo-orchitis, prostatitis and serious complications like disseminated gonococcal infection, meningitis, and endocarditis.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02130"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Concurrent pseudogout and septic arthritis in native knee joint by ESBL-producing E. coli: Successful management with cefmetazole and surgery","authors":"Yoshihiro Aoki , Yutaka Tsukamoto , Junichiro Maeda , Atsuko Tachikawa , Daisuke Sugawara , Kensuke Takahashi , Shuhei Yamano , Koichi Hayakawa , Osamu Tasaki","doi":"10.1016/j.idcr.2025.e02262","DOIUrl":"10.1016/j.idcr.2025.e02262","url":null,"abstract":"<div><div>Septic arthritis in native joints due to extended-spectrum beta-lactamase (ESBL)-producing bacteria is rare, and there is limited information in the current literature. An 85-year-old woman with rheumatoid arthritis experienced persistent left knee pain and mobility issues for several days. Initially, the patient was diagnosed with pseudogout by calcium pyrophosphate deposition and leukocytes in the aspiration fluid. However, joint puncture fluid culture on admission revealed the presence of ESBL-producing <em>Escherichia coli</em>, whereas magnetic resonance imaging showed effusion in the left knee joint and abnormal signal changes in the surrounding soft tissue. Cefmetazole was administered and the patient underwent orthopedic surgery involving arthritis scraping, debridement, and drainage. Post-intervention, she experienced alleviation of knee pain, leading to transfer to a rehabilitation facility on the 35th day of hospitalization. This case highlights an unusual septic arthritis case caused by ESBL-producing bacteria in a nonprosthetic pseudogout-affected joint, underscoring cefmetazole’s therapeutic potential.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02262"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143935042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02237
Kazuhiro Ishikawa, Nobuyoshi Mori
{"title":"Recurrent paradoxical reactions as non-communicating hydrocephalus and basal meningitis in a non-HIV patient with tuberculous meningitis and tuberculoma","authors":"Kazuhiro Ishikawa, Nobuyoshi Mori","doi":"10.1016/j.idcr.2025.e02237","DOIUrl":"10.1016/j.idcr.2025.e02237","url":null,"abstract":"<div><h3>Background</h3><div>Tuberculosis meningitisis the most devastating form of Tuberculosis, causing high mortality or disability. Paradoxical neuro-inflammatory reactions, which occur despite appropriate anti-TB chemotherapy, may reflect the host response to dead and dying bacterial.</div></div><div><h3>Case report</h3><div>We report a case involving paradoxical reaction, effectively managed with emergent external ventricular drainage (EVD). The patient, a healthy 30-year-old Burmese woman, was diagnosed with disseminated tuberculosis involving pulmonary disease, vertebral osteomyelitis, and meningitis. Treatment included isoniazid (INH) 300 mg/day, rifampicin (RFP) 450 mg/day, ethambutol (EB) 750 mg/day, pyrazinamide (PZA) 1250 mg/day, levofloxacin (LVFX) 500 mg/day, and Dexamethasone (DEX) 0.4 mg/kg/day. A week after treatment initiation, she experienced the a paradoxical reaction but found relief with symptomatic treatment. Due to susceptibility of tuberculosis, we transitioned her to INH+RFP+LVFX, and DEXA was discontinued after two months. On day 66, she was readmitted with worsening symptoms and was diagnosed with a second paradoxical reaction and hydrocephalus. Neurosurgery inserted an EVD tube and resumed DEXA. The patient showed significant improvement, and the EVD was subsequently removed. DEXA was stopped after 4 months.There was no recurrence in one year.</div></div><div><h3>Conclusion</h3><div>During the treatment of TBM, a paradoxical reaction can occur at any time. Therefore, we recommend the necessity of collaborating with a neurosurgeon to facilitate emergency EVD drainage for the management of hydrocephalus.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02237"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143902604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}