IDCases最新文献

{"title":"Severe invasive streptococcal infection in a patient with COVID-19: A case report","authors":"Yuki Matsuura ,&nbsp;Mone Murashita ,&nbsp;Takayoshi Oyasu ,&nbsp;Akira Kodate ,&nbsp;Yoshihiro Sadamoto ,&nbsp;Akio Endo ,&nbsp;Hisako Sageshima ,&nbsp;Takumi Tsuchida","doi":"10.1016/j.idcr.2025.e02169","DOIUrl":"10.1016/j.idcr.2025.e02169","url":null,"abstract":"<div><div>A 63-year-old male with a history of hypertension had contracted Coronavirus Disease-2019 (COVID-19) five days before visiting our hospital and was recovering at home. He was brought to the hospital for emergency care because of bilateral leg pain, diarrhea, and shortness of breath. On arrival to the hospital, the patient was already suffering from multiple organ failure and was admitted to the intensive care unit. <em>Streptococcus dysgalactiae</em> subsp<em>. equisimilis</em> (SDSE) was detected in blood and sputum cultures, and we started antimicrobial therapy for septic shock/streptococcal toxic shock syndrome. However, multiple organ failure progressed, and the patient died one day after admission. This case suggests the possibility of immunosuppression due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The patient had no history of immunodeficiency, and COVID-19 may have contributed to the poor outcome. COVID-19 combined with SDSE sepsis has not been previously reported. Therefore, this case was considered rare.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02169"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transmission of human herpesvirus-8 through liver transplantation and development of post-transplantation Kaposi sarcoma: A case report","authors":"Julius Leander Ross Clemmesen ,&nbsp;Nicoline Arentoft ,&nbsp;Nicolai Aagaard Schultz ,&nbsp;Moises Alberto Suarez-Zdunek ,&nbsp;Annika Loft ,&nbsp;Nikolai Kirkby ,&nbsp;Jens Georg Hillingsø ,&nbsp;Gro Linno Willemoe ,&nbsp;Michael Perch ,&nbsp;Christian Ross Pedersen ,&nbsp;Susanne Dam Nielsen","doi":"10.1016/j.idcr.2025.e02263","DOIUrl":"10.1016/j.idcr.2025.e02263","url":null,"abstract":"<div><h3>Introduction</h3><div>Kaposi sarcoma is a vascular tumour associated with human herpesvirus-8 (HHV-8) infection. Due to immunosuppressive treatment, solid organ transplant recipients infected with HHV-8 have increased risk of Kaposi sarcoma. The risk of being infected with HHV-8 is associated with higher age, male sex, non-White ethnicity, being a man who has sex with men (MSM) and use of recreational drugs. Post-transplant Kaposi sarcoma is rare in HHV-8 low-prevalence areas. We report the first case of a liver transplant recipient developing Kaposi sarcoma following donor-transmitted HHV-8 infection in Denmark.</div></div><div><h3>Case presentation</h3><div>A 51-year-old male underwent uncomplicated liver transplantation at Copenhagen University Hospital – Rigshospitalet, and received standard immunosuppressive treatment with tacrolimus, mycophenolate mofetil and prednisolone. Five months post-transplantation the patient was admitted with abdominal pain, diarrhoea, and dehydration. Ultrasound imaging and PET/CT scan revealed multiple liver tumours. Biopsy from liver tumour diagnosed visceral post-transplantation Kaposi sarcoma. Kaposi sarcoma was successfully treated with reduction of immunosuppressive treatment and conversion from tacrolimus to everolimus, resulting in viral clearance and complete metabolic and structural tumour response. A review of the donor post-transplantation revealed multiple risk factors for being infected with HHV-8, with subsequent analysis confirming the donor was positive for HHV-8.</div></div><div><h3>Discussion</h3><div>Even in low-prevalence areas, there are benefits of targeted screening for HHV-8 in high-risk organ donors and recipients described in the literature and highlighted in the current case. Post-transplantation Kaposi sarcoma due to HHV-8 may be managed with reduction in immunosuppressive treatment and conversion from calcineurin inhibitors to mTOR inhibitors.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02263"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144068646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulmonary mass with actinomyces infection mimicking malignancy: A case illustrated","authors":"Hidenori Takahashi ,&nbsp;Satomi Fujihara ,&nbsp;Saori Shimizu","doi":"10.1016/j.idcr.2025.e02264","DOIUrl":"10.1016/j.idcr.2025.e02264","url":null,"abstract":"<div><div>We encountered a case of pulmonary actinomycosis diagnosed through bronchoscopy, initially suspected as lung cancer originating from the bullae, and the PET-CT findings did not rule out malignancy. Pulmonary actinomycosis is a rare lung infection that often mimics cancer. Its anaerobic nature and prolonged culture time make diagnosis challenging without strong clinical suspicion.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02264"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic invasive fungal rhinosinusitis in a patient with chronic migraine","authors":"Mengfan Sun,&nbsp;Yang Liu","doi":"10.1016/j.idcr.2025.e02281","DOIUrl":"10.1016/j.idcr.2025.e02281","url":null,"abstract":"<div><div>Chronic invasive fungal rhinosinusitis (CIFRS) is a rare disease caused by fungal infection and has an insidious course, which generally presents with headache at first, resulting in misdiagnosis and underestimation. Migraine is the most common primary headache and has symptoms mimicking rhinosinusitis. As a result, this may contribute to confusion of diagnosis when we consider the reason of headache, especially in patients suffering from migraine and rhinosinusitis at the same time. Here, we report a patient diagnosed with CIFRS and chronic migraine with the help of next-generation sequencing examination, to provide a reference in clinical treatment.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02281"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144239985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new approach to treat carbapenem resistant Acinetobacter baumannii (CRAB) bacteremia using sulbactam-avibactam combination: A case report","authors":"Sameer Alzaidi,&nbsp;Manahil Alharthi,&nbsp;Hams Alshammamri,&nbsp;Yasir Almalki,&nbsp;Osama Almalki,&nbsp;Shahad Alqahtani,&nbsp;Mohammed Alosaimi,&nbsp;Nouran Althumali","doi":"10.1016/j.idcr.2025.e02296","DOIUrl":"10.1016/j.idcr.2025.e02296","url":null,"abstract":"<div><div>Carbapenem resistant <em>Acinetobacter baumannii</em> (CRAB) infections are serious disease that can be fatal. Only a few therapeutic options are available, with conflicting data for their meaningful clinical outcomes. Here, we report a case of 83-year-old female CRAB bacteremia that was successfully treated with ceftazidime-avibactam and ampicillin-sulbactam combination after failing guidelines directed therapy.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02296"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144365696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Black mold in the bag room: First case of Arthrocladium tropicale peritonitis in a peritoneal dialysis patient","authors":"Rutchanee Chieochanthanakij ,&nbsp;Thunvarat Saejew ,&nbsp;Panthira Passorn ,&nbsp;Dhammika Leshan Wannigama ,&nbsp;Talerngsak Kanjanabuch","doi":"10.1016/j.idcr.2025.e02383","DOIUrl":"10.1016/j.idcr.2025.e02383","url":null,"abstract":"<div><div>We report the first human case of <em>Arthrocladium tropicale</em> peritonitis in a PD patient presenting with abdominal pain and low effluent cell counts. Diagnosis was confirmed by rDNA sequencing. The isolate was resistant to posaconazole but susceptible to amphotericin B. Treatment with intravenous amphotericin B, in conjunction with prompt catheter removal, resulted in full recovery, consistent with ISPD guideline principles. Environmental findings of damp walls and ant infestation near PD supplies highlight the importance of strict environmental control to prevent contamination from opportunistic fungi in PD.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"42 ","pages":"Article e02383"},"PeriodicalIF":1.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145221859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycotic cyst: Case report","authors":"Oviya Selvam ,&nbsp;Yogindher Singh R. ,&nbsp;M.D. Gowthaman ,&nbsp;Manobalan K. ,&nbsp;K. Subashree","doi":"10.1016/j.idcr.2024.e02120","DOIUrl":"10.1016/j.idcr.2024.e02120","url":null,"abstract":"<div><div>Phaeohyphomycotic cyst is a common subcutaneous form of phaeohyphomycosis in which patients can present with subcutaneous plaques, nodules, etc., It is an infrequent presentation and is most reported in immunocompromised individuals. Diagnosis is confirmed by histopathological and mycological demonstration of the organism. The treatment is by surgical excision with systemic antifungals. We report a rare case of asymptomatic Mycotic cyst in an immunocompetent individual.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02120"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142933008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disseminated Mycobacterium Chelonae infection in an immunocompromised adult: An uncommon etiology of skin infection","authors":"Biruk Amare,&nbsp;Andrew Mangano,&nbsp;Moumita Sarker,&nbsp;Sagun Adhikari","doi":"10.1016/j.idcr.2024.e02132","DOIUrl":"10.1016/j.idcr.2024.e02132","url":null,"abstract":"<div><div><em>Mycobacterium Chelonae</em> is a rapidly growing nontuberculous mycobacterium (NTM) that is ubiquitous in the environment and is associated with skin and soft tissue infections (1). Because <em>Mycobacterium Chelonae</em> is an opportunistic infection, it can present as skin abscess, cellulitis, osteomyelitis, pulmonary infection or disseminated infections, particularly in individuals with compromised immune systems or underlying lung conditions such as cystic fibrosis or bronchiectasis. <em>M.Chelonae</em> is one of the most pathogenic rapidly growing mycobacteria (RGM). Diagnosing RGM and distinguishing it from Mycobacterium tuberculosis is important because public health tracking and management is different in these two organisms. Antibiotic susceptibility testing can also provide valuable clues to the species identification of RGM as each species has a specific in vitro antibiotic susceptibility pattern (2). Although incidence of <em>M. Chelonae</em> is increasing, these infections often remain misdiagnosed. This case report discusses the clinical presentation, diagnostic challenges, the rationale for early empiric treatment, and therapeutic options for <em>M. Chelonae</em> infection, emphasizing the importance of timely intervention in immunocompromised individuals.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02132"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11732071/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive management of actinomycetoma in a young male: A case report from Somalia","authors":"Mohamed Adam Mahamud ,&nbsp;Claude M. Muvunyi ,&nbsp;Ayman Ahmed ,&nbsp;Emmanuel Edwar Siddig","doi":"10.1016/j.idcr.2024.e02141","DOIUrl":"10.1016/j.idcr.2024.e02141","url":null,"abstract":"<div><div>Mycetoma is a neglected tropical disease that predominantly affects individuals in low socioeconomic strata, primarily in tropical and subtropical regions. This case report describes a 20-year-old male student from Bahdo City, Somalia, who presented with a persistent cervical mass following a history of trauma. The patient exhibited vital signs within normal limits, and imaging studies, including ultrasound and computed tomography, revealed well-defined cystic masses. A Fine Needle Aspiration cytology confirmed the diagnosis of actinomycetoma by revealing sheets of neutrophils, multinucleated giant cells, and branching filamentous bacteria structures. The patient was treated with co-trimoxazole and amikacin, resulting in significant improvement after three months, highlighting the critical role of early diagnosis and appropriate medical management in enhancing patient outcomes. This report emphasizes the importance of thorough clinical evaluation and the use of cytological methods, particularly in resource-limited settings, to expedite the diagnosis and treatment of actinomycetoma.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02141"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scrub typhus associated with reactive arthritis: A case report and literature review","authors":"Shinya Yamanaka ,&nbsp;Kazuhiro Ishikawa ,&nbsp;Miyako Kon ,&nbsp;Junko Aoki ,&nbsp;Kunimichi Saeki ,&nbsp;Junta Tanaka","doi":"10.1016/j.idcr.2024.e02143","DOIUrl":"10.1016/j.idcr.2024.e02143","url":null,"abstract":"<div><div>Scrub typhus (tsutsugamushi disease) is an acute febrile illness caused by <em>Orientia tsutsugamushi</em>, often found in Asia and Oceania. The presence of an eschar, characterized by a crust, is a key diagnostic finding. Many symptoms of this disease are already known, however reactive arthritis following scrub typhus is very rare. Here, we present a case of 79-year-old man who was referred to our hospital because of continuous fever and left shoulder pain. We found 4-fold rise in <em>Orientia tsutugamushi</em>-specific IgG titer using paired serum samples and <em>Orientia</em> sp. genes by real-time PCR from a crust of right thigh. And the left shoulder joint image was consistent with aseptic arthritis; thus we diagnosed as scrub typhus with reactive arthritis. This case highlights the importance of recognizing reactive arthritis as a symptom of scrub typhus. In this report, we also review published cases of reactive arthritis associated with scrub typhus, and we suppose that this arthritis related to this infection may recover after antibiotic use and have a good prognosis. Physicians' awareness of newly appeared arthritis may contribute to facilitate early diagnosis, and may improve the course of such patients.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02143"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11753909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}