IDCases最新文献_第10页

Ecthyma amidst the global monkeypox outbreak: A key differential? —A case series 全球猴痘爆发中的湿疹：一个关键的区别？-一个案例系列。

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02125

Houriah Y. Nukaly , Waseem K. Alhawsawi , Jumanah Y. Nassar , Aymen Alharbi , Sarah Tayeb , Nada Rabie , Moayad Alqurashi , Raghda Faraj , Rehab Fadag , Mohammed Samannodi

{"title":"Ecthyma amidst the global monkeypox outbreak: A key differential? —A case series","authors":"Houriah Y. Nukaly , Waseem K. Alhawsawi , Jumanah Y. Nassar , Aymen Alharbi , Sarah Tayeb , Nada Rabie , Moayad Alqurashi , Raghda Faraj , Rehab Fadag , Mohammed Samannodi","doi":"10.1016/j.idcr.2024.e02125","DOIUrl":"10.1016/j.idcr.2024.e02125","url":null,"abstract":"<div><h3>Background</h3><div>Ecthyma is a deeper form of impetigo involving the epidermis and dermis causing ulcerative plaques. Pathogens commonly responsible for the disease (group A beta-hemolytic streptococcus and Staphylococcus aureus) typically afflicts children, presenting during early stages with skin lesions that can closely resemble other vesicular and ulcerative dermatoses, such as those observed in mpox infection. The ongoing global outbreak of monkeypox has escalated the urgency for clinicians to accurately differentiate between these conditions due to their overlapping dermatological manifestations. Through this series, we intend to demonstrate the diverse clinical presentations of ecthyma observed in non-endemic regions, which may closely mimic those of monkeypox.</div></div><div><h3>Case presentation</h3><div>The first case describes a 12- year-old male with a history of atopic dermatitis, presenting with a vesicular rash initially suspected to be monkeypox. However, diagnosis via skin punch biopsy and cultures revealed ecthyma. The second case involved an 18-year-old male with acute, rapidly progressing ulcerated lesions and systemic symptoms. Differential diagnosis included toxic shock syndrome and necrotizing fasciitis, but histopathological findings confirmed ecthyma. The third case featured a 55-year-old woman with rapidly developing skin lesions on her hand, resolved through empirical antibiotic therapy, further confirming the diagnosis.</div></div><div><h3>Conclusion</h3><div>misdiagnosis and thus, delayed treatment of ecthyma leads to severe unfavourable outcomes. Given its rare occurrence yet fatal potential, and the current global vigilance due to the monkeypox outbreak, it is vital for healthcare providers to include ecthyma in the differential diagnosis of necrotic and ulcerative skin lesions.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02125"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurobrucellosis manifested by recurrent aseptic meningitis: A case report 以复发性无菌性脑膜炎为表现的神经布鲁氏菌病1例

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02193

Reza Razaghi , Fatemeh Kourkinejad_Gharaei , Forough Faroughi

{"title":"Neurobrucellosis manifested by recurrent aseptic meningitis: A case report","authors":"Reza Razaghi , Fatemeh Kourkinejad_Gharaei , Forough Faroughi","doi":"10.1016/j.idcr.2025.e02193","DOIUrl":"10.1016/j.idcr.2025.e02193","url":null,"abstract":"<div><div>Brucellosis is an endemic zoonotic disease in LMIC countries. Neurobrucellosis is a rare and serious complication that affects 3–5 % of cases worldwide. We report the successful treatment of a 31-year-old woman who presented with a chief complaint of headache and nausea. Headache was started six months before admission in the frontal and occipital area with radiation to the neck. The patient hospitalized three times within last six months with diagnosis of aseptic meningitis. Brucellosis, tuberculosis, and syphilis tests and CSF fluid analysis were requested. Neutrophilia and pleocytosis in CSF fluid. Analysis of CSF fluid for cytology and PCR test for HSV-1&2 was negative. Rheumatologic tests for SLE, Behcet's disease and sarcoidosis were also negative. Test results was as follow: Wright: 1/320, Coombs Wright: 1/640, 2ME: 1/160, Brucella IgG: 25(Positive). According to the test results, combined treatment with rifampin, Co-trimoxazole, and ceftriaxone was performed for neurobrucellosis for nine months. Considering the endemic prevalence of brucellosis in this region, the rare manifestations of this disease should be considered.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02193"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fusobacterium necrophorum associated with pelvic infections: A case series and literature review 与盆腔感染相关的坏死杆菌：病例系列和文献综述

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02190

Manasa Brown , Sabrina Imam , Jade Pagkas-Bather

引用次数: 0

Ictal vomiting as an unusual presentation of herpes simplex encephalitis ‐ Pathophysiological and therapeutic perspectives 发作性呕吐是单纯疱疹脑炎的一种不寻常的表现——病理生理和治疗观点

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02186

Hosna Elshony , Abdelrahman Idris , Abdulaziz Al-Ghamdi , Rakan Almuhanna , Waleed Amsaib M. Ahmed

{"title":"Ictal vomiting as an unusual presentation of herpes simplex encephalitis ‐ Pathophysiological and therapeutic perspectives","authors":"Hosna Elshony , Abdelrahman Idris , Abdulaziz Al-Ghamdi , Rakan Almuhanna , Waleed Amsaib M. Ahmed","doi":"10.1016/j.idcr.2025.e02186","DOIUrl":"10.1016/j.idcr.2025.e02186","url":null,"abstract":"<div><h3>Introduction</h3><div>Herpes Simplex Encephalitis (HSE) is a formidable neurological infection that is often challenging to diagnose owing to its diverse clinical manifestations. This case report details the clinical odyssey of a sixty-year-old female with diabetes, hypothyroidism, and hypertension, who presented with fever, vomiting, and evolving neurological symptoms.</div></div><div><h3>Case Presentation</h3><div>The patient's initial admission failed to yield a diagnosis, and her condition worsened, marked by behavioral changes, cognitive decline, and focal seizures. Neuroimaging revealed characteristic findings, confirming non-hemorrhagic herpetic encephalitis. Despite antiviral and antiepileptic therapy, persistent vomiting prompted further investigations, uncovering infrequent right temporal sharp waves on EEG, leading to a diagnosis of \"ictus emiticus.\"</div></div><div><h3>Conclusion</h3><div>This case of Herpes Simplex Encephalitis (HSE) underscores the diverse clinical spectrum and challenges in management. The patient's atypical presentation underscores the importance of considering HSE in patients with fever and unexplained persistent vomiting for early diagnosis and better prognosis.</div><div>Diagnostic tools (neuroimaging, cerebrospinal fluid analysis, and electroencephalography) confirmed HSE involvement in the right temporal lobe, emphasizing the strong association between HSV encephalitis and seizures, which can be explained by various mechanisms.</div><div>Timely antiviral therapy and tailored antiepileptic strategies led to gradual clinical improvement, showcasing the potential of valproate beyond antiepileptic use.</div><div>This case prompts further exploration into HSE's pathophysiology and treatment. It emphasizes individualized patient care and vigilance for potential post-resolution sequelae, contributing to our evolving understanding of HSE.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02186"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143386997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A unique case of herpetic keratitis manifesting as recurrent preseptal cellulitis 一例独特的带状角膜炎表现为复发性隔膜蜂窝织炎

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02187

Emily Miller , Maxwell Ward , Tasaduq Fazili , Ekta Bansal

引用次数: 0

Pyogenic vertebral osteomyelitis and iliopsoas muscle abscess caused by non-typhoidal Salmonella rapidly identified by genetic testing in an immunocompetent teenage boy without hemoglobinopathies 由非伤寒沙门氏菌引起的化脓性椎体骨髓炎和髂腰肌脓肿，通过基因检测在无血红蛋白病的免疫功能正常的青少年中迅速鉴定出来

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02211

Jun Hirai , Nobuaki Mori , Daisuke Sakanashi , Yuichi Shibata , Nobuhiro Asai , Mao Hagihara , Hiroshige Mikamo

{"title":"Pyogenic vertebral osteomyelitis and iliopsoas muscle abscess caused by non-typhoidal Salmonella rapidly identified by genetic testing in an immunocompetent teenage boy without hemoglobinopathies","authors":"Jun Hirai , Nobuaki Mori , Daisuke Sakanashi , Yuichi Shibata , Nobuhiro Asai , Mao Hagihara , Hiroshige Mikamo","doi":"10.1016/j.idcr.2025.e02211","DOIUrl":"10.1016/j.idcr.2025.e02211","url":null,"abstract":"<div><div>Vertebral osteomyelitis caused by non-typhoidal <em>Salmonella</em> spp. is exceedingly rare, particularly among immunocompetent children. This report presents an unusual case of lumbar osteomyelitis and an iliopsoas muscle abscess caused by non-typhoidal Salmonella in an immunocompetent pediatric patient with a multidrug allergy. A 13-year-old boy presented with fever and lumbar pain. Diagnostic imaging revealed lumbar osteomyelitis and an iliopsoas abscess. Blood culture and initial iliopsoas puncture tissue sample test results were negative. Therefore, cefazolin was administered as empirical therapy for covering typical organisms such as <em>Staphylococcus aureus</em> and <em>Streptococcus</em> species causing vertebral osteomyelitis in healthy children. However, genetic testing of the biopsy sample of the vertebral tissue subsequently identified <em>Salmonella</em> spp. as the causative agent. Culture of the vertebral tissue also yielded <em>Salmonella</em> spp., with the O-antigen identified as type 4. Antibiotic selection was challenging because of the patient's drug allergies and age. Treatment was commenced with ceftriaxone and later changed to ampicillin owing to adverse drug reactions. The side effects, such as rash, fever, and nausea, persisted after switching to oral sulfamethoxazole-trimethoprim, which was later changed to amoxicillin. Although the treatment duration of vertebral <em>Salmonella</em> osteomyelitis in children is not standardized, we treated the patient for 9 weeks based on previously reported evidence. Rapid identification of the causative organism is important because vertebral osteomyelitis requires long-term treatment and treatment options may be limited, particularly in pediatric patients. Physicians should consider genetic testing to identify the causative organism of osteomyelitis.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02211"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143817481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic granulomatous inflammation caused by latent tuberculosis presented as a subcutaneous mass: A case report with review of literature 由潜伏肺结核引起的慢性肉芽肿性炎症表现为皮下肿块：病例报告与文献综述

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02226

Hee Gyun Yang , Jungho Kim , Jung-Han Kim

引用次数: 0

Challenging infective endocarditis: A case of Pseudomonas aeruginosa with emergent antibiotic resistance 挑战性感染性心内膜炎：1例铜绿假单胞菌出现抗生素耐药性

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02231

Marc Pedrosa Aragón , Armand Sellas Farres , Sonia Calzado Isbert , Mateu Espasa-Soley

{"title":"Challenging infective endocarditis: A case of Pseudomonas aeruginosa with emergent antibiotic resistance","authors":"Marc Pedrosa Aragón , Armand Sellas Farres , Sonia Calzado Isbert , Mateu Espasa-Soley","doi":"10.1016/j.idcr.2025.e02231","DOIUrl":"10.1016/j.idcr.2025.e02231","url":null,"abstract":"<div><div>Infective endocarditis (IE) caused by gram-negative microorganisms, particularly Pseudomonas aeruginosa, is a rare but serious condition. This case report details a 76-year-old male who presented with fever and mild urinary symptoms following a recent bacteremia treated with ciprofloxacin. Initial evaluation revealed positive blood cultures for multi-susceptible <em>P. aeruginosa</em> and an abdominal abscess. Despite a favorable initial response to treatment, the patient developed a cerebral infarction due to a septic embolism. Subsequent cultures revealed resistance to piperacillin/tazobactam and ceftazidime, prompting escalation of antibiotic therapy. A transesophageal echocardiogram confirmed infective endocarditis with a vegetative mass on the aortic valve. The patient underwent surgical intervention, with positive cultures from the valve confirming the resistant strain. Following six weeks of targeted antibiotic therapy, he remained asymptomatic for over a year. This case underscores the importance of monitoring for endocarditis in patients with <em>P. aeruginosa</em> bacteremia and highlights the challenges posed by emerging antibiotic resistance.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02231"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Failure of Gallium-68 citrate to detect large, enhancing, intracerebral central nervous system tuberculomas: A cautionary tale 枸橼酸镓-68检测颅内中枢神经系统大的增强结核瘤失败：一个警示故事

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02155

Selwyn Selva Kumar , Adrian Keith Noronha , Julie Hephzibah , Harshad Arvind Vanjare , Abi Manesh

引用次数: 0

Haemophilus Influenzae Type F as a rare cause of septic arthritis F型流感嗜血杆菌是脓毒性关节炎的罕见病因

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02204

Charles E. McCafferty , Luke McKinnon , Tristan Rappo

引用次数: 0