IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02225
Ka Lip Chew, Ker Xin Tan, Jeanette Teo
{"title":"Mycoplasma hominis chorioamnionitis associated with preterm delivery: A case report","authors":"Ka Lip Chew, Ker Xin Tan, Jeanette Teo","doi":"10.1016/j.idcr.2025.e02225","DOIUrl":"10.1016/j.idcr.2025.e02225","url":null,"abstract":"<div><div>This case report highlights a <em>Mycoplasma hominis</em> infection associated with chorioamnionitis following preterm premature rupture of membranes (PPROM) in a 43-year-old pregnant woman at 30 weeks gestation. The patient presented with a mild fever and increased white cell count, leading to the diagnosis of chorioamnionitis. Empiric antibiotic treatment with ampicillin and gentamicin was initiated, later switched to ceftriaxone. <em>Mycoplasma hominis</em> was identified through routine placental cultures on CDC Anaerobic Blood Agar, and confirmed by whole-genome sequencing (WGS) using the Illumina HiSeq platform. The WGS revealed no resistance mutations to macrolides, quinolones, or tetracyclines, and predicted susceptibility to these antimicrobials. The isolate exhibited a high number of SNP differences (5471–8074) compared to publicly available <em>M. hominis</em> genomes. No specific anti-<em>Mycoplasma</em> treatment was administered, and both mother and newborn had favourable outcomes. This case underscores the importance of considering <em>Mycoplasma</em> infections in pregnancy complications and the need for specialized testing, as routine cultures may fail to detect these organisms. WGS offers a comprehensive approach to pathogen identification and drug resistance profiling, though the clinical impact of targeted antimicrobial therapy for <em>Mycoplasma</em> infections in such cases remains uncertain.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02225"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02208
Maria Del Pilar Morel Almonte , Jose Guillermo Castro
{"title":"A case of isolated meningitis caused by Bartonella henselae","authors":"Maria Del Pilar Morel Almonte , Jose Guillermo Castro","doi":"10.1016/j.idcr.2025.e02208","DOIUrl":"10.1016/j.idcr.2025.e02208","url":null,"abstract":"<div><div>Central nervous manifestations of bartonella infection are uncommon and can vary from encephalitis, meningitis, nerve palsy as well as ocular involvement. Most of these manifestations are described in immunocompromised individuals. We report a case of a previously healthy 42-year-old male who presented to the hospital with 4-weeks of fever and headache and found with meningeal signs on physical exam. He reported been scratched by a stray cat at work some days before his symptoms started. He remained febrile in the hospital. Initial work up was unrevealing, but CSF analysis showed pleocytosis, elevated protein and low CSF glucose- plasma glucose ratio consistent with CNS bacterial infection. Blood and CSF cultures were negative. <em>Bartonella henselae</em> titers in serum were found to be elevated. No other source of infection was identified. Patient was diagnosed with isolated aseptic meningitis secondary to <em>Bartonella henselae infection</em>. Treatment with doxycycline and rifampin was started with good response and resolution of symptoms.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02208"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143792794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02223
Chunyan Gao, Wujun Jiang, Chuangli Hao, Yuqing Wang
{"title":"Laryngitis caused by Talaromyces marneffei in a child","authors":"Chunyan Gao, Wujun Jiang, Chuangli Hao, Yuqing Wang","doi":"10.1016/j.idcr.2025.e02223","DOIUrl":"10.1016/j.idcr.2025.e02223","url":null,"abstract":"<div><div>In this report evaluated a child was diagnosed with Talaromyces marneffei laryngitis with typical pictures.The classical laryngeal lesions caused by Talaromyces marneffei in our case are both educational and interesting.This report would help clinicians recognize laryngitis which caused by Talaromyces marneffei.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02223"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143843719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02205
YunTao Gu , Yuan Zhou , TianQiong Hu , Hai Zhao , YongPing Wang , YongXiong He
{"title":"Abscesses of the spine and iliac fossa caused by infection with the opportunistic bacterium Fusobacterium nucleatum","authors":"YunTao Gu , Yuan Zhou , TianQiong Hu , Hai Zhao , YongPing Wang , YongXiong He","doi":"10.1016/j.idcr.2025.e02205","DOIUrl":"10.1016/j.idcr.2025.e02205","url":null,"abstract":"<div><div>We present a case of spinal and iliac fossa infection caused by <em>Fusobacterium nucleatum</em> in a 52-year-old male patient with unexplained back pain. Notably, the patient had no history of periodontal infections.Magnetic resonance imaging (MRI) revealed abscesses at the L3-4 vertebrae and hip, with dura mater and cauda equina compression.Next-generation sequencing (NGS) of the aspirate confirmed the presence of <em>Fusobacterium nucleatum</em>. The patient was treated with antibiotics (carbapenems, and metronidazole) and underwent surgical procedures for abscess drainage and internal fixation, resulting in the removal of 1000 ml of pus. Following a 46-day recovery period, the patient made a full recovery.This rare infection poses a significant diagnostic challenge due to its insidious onset and low blood culture sensitivity. The role of next-generation sequencing (NGS) in this context is paramount, as it has been instrumental in arriving at an accurate diagnosis and formulating an effective treatment plan. In view of the challenges posed by this infection, NGS emerges as a crucial tool for the diagnosis and management of unexplained infections.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02205"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143724710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02198
Malleswari Ravi , Cristine Arcilla , Gurjit Kaeley
{"title":"A rare case of aortitis and occlusive iliac thrombus due to Campylobacter fetus bacteremia","authors":"Malleswari Ravi , Cristine Arcilla , Gurjit Kaeley","doi":"10.1016/j.idcr.2025.e02198","DOIUrl":"10.1016/j.idcr.2025.e02198","url":null,"abstract":"<div><div>A 66-year-old male presented with 1-week of fever and generalized weakness. Workup revealed <em>Campylobacter fetus</em> bacteremia. Further investigation with imaging showed distal abdominal aortitis with occlusive thrombus in the right common iliac artery. <em>C. fetus</em> bacteremia with endovascular localization is clinically very rare but with high mortality rate.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02198"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143726049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02191
Bing Tian , Pan Wang , Chun Shan , Cheng Gao , Qun Zhang
{"title":"Organizing pneumonia in a patient following treatment of chronic hepatitis B with pegylated interferon alfa-2b: A case report","authors":"Bing Tian , Pan Wang , Chun Shan , Cheng Gao , Qun Zhang","doi":"10.1016/j.idcr.2025.e02191","DOIUrl":"10.1016/j.idcr.2025.e02191","url":null,"abstract":"<div><div>Chronic hepatitis B is a major cause of liver disease in China. One of the treatments currently recommended is interferon (IFN). Although uncommon, there have been some case reviews on patients with hepatitis C with pulmonary adverse effects following treatment with IFN. Our case report is of a patient who acquired organizing pneumonia after he was treated for hepatitis B with pegylated IFN alfa-2b. We aim to raise awareness of the pulmonary toxicity of interferon, especially as it is increasingly used to treat patients with chronic hepatitis B.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02191"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143519872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02173
Charles W. Ryan , Rajesh C. Rao
{"title":"Bilateral acute macular neuroretinopathy following influenza A infection","authors":"Charles W. Ryan , Rajesh C. Rao","doi":"10.1016/j.idcr.2025.e02173","DOIUrl":"10.1016/j.idcr.2025.e02173","url":null,"abstract":"<div><div>A previously healthy 18-year-old female presented with bilateral cecocentral scotomas two-days after onset of confirmed Influenza A infection, consistent with a post-viral acute macular neuroretinopathy (AMN). Fundoscopy revealed bilateral small petaloid lightening in the nasal macula, and optical coherence tomography revealed thinning of the interdigitation zone, ellipsoid zone, and outer nuclear layer bilaterally. Scotomas and associated imaging findings showed partial improvement in the weeks following diagnosis. This case demonstrates that AMN may be triggered Influenza A infection, and that resulting scotomas and retinal thinning may improve in the weeks following the initial insult.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02173"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143340490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2024.e02142
Anne Schneider , Jannik Fasse , Dennis Tappe , Christoph Lübbert , Henning Trawinski
{"title":"Case report: Dirofilarial infection of the face","authors":"Anne Schneider , Jannik Fasse , Dennis Tappe , Christoph Lübbert , Henning Trawinski","doi":"10.1016/j.idcr.2024.e02142","DOIUrl":"10.1016/j.idcr.2024.e02142","url":null,"abstract":"<div><div>An 18-year-old male patient from Ukraine, living in Germany for 2 years, presented with a painless subcutaneous swelling on the left cheek that had been present for several months. Finally, the diagnosis of subcutaneous dirofilariasis caused by <em>Dirofilaria repens</em> was confirmed by 12S rRNA gene PCR and sequencing from tissue by nematode-specific PCRs followed by sequencing after surgical resection of the lesion. Microfilaremia was ruled out and no further treatment was required. Subcutaneous filariasis continues to spread in Central Europe due to climate change, the expansion of vector mosquitoes and the mobility of humans and dogs.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02142"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
IDCasesPub Date : 2025-01-01DOI: 10.1016/j.idcr.2025.e02236
Mercedes Martinez-Gil , Mohammed Wajid Hussain , Lindsey R. Theut , Maria Miller , Ashley Ezekpo , William D. Dachman
{"title":"Fever of unknown origin: Unravelling the mystery of Q fever and coccidioidomycosis coinfection – Case report","authors":"Mercedes Martinez-Gil , Mohammed Wajid Hussain , Lindsey R. Theut , Maria Miller , Ashley Ezekpo , William D. Dachman","doi":"10.1016/j.idcr.2025.e02236","DOIUrl":"10.1016/j.idcr.2025.e02236","url":null,"abstract":"<div><div>In this case, we present a rare occurrence of a zoonotic infection, Q fever, coexisting with a fungal infection, coccidioidal meningitis. When patients present with ambiguous symptoms, it becomes challenging to attribute their presentation to a particular disorder or disease, especially when they test negative for common infectious etiologies. This case highlights both the importance of considering rare infections early on and the possibility that multiple infectious agents can coexist, simultaneously contributing to a patient’s illness.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02236"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143890564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Human parvovirus B19 as an unusual cause of Guillain-Barré syndrome: A case report","authors":"Elisa Creuzet , Wendy Pulby , Claire Dupuis , Christine Archimbaud , Amélie Brebion , Hélène Chabrolles , Mathilde Picard , Christel Regagnon , Audrey Mirand , Bertrand Souweine , Cécile Henquell","doi":"10.1016/j.idcr.2024.e02135","DOIUrl":"10.1016/j.idcr.2024.e02135","url":null,"abstract":"<div><div>Human Parvovirus B19 (B19V) is rarely observed in patients with Guillain-Barré syndrome. We report the case of a patient with rapidly progressive functional impotence of the limbs. B19V was detected in both blood and CSF samples. The patient improved clinically after plasma exchanges, but mild functional impotence persisted 2 months later.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02135"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}