IDCases最新文献

{"title":"Case report: Persistent COVID-19 in a patient with B cell lymphoma refractory to antiviral treatment due to resistance to Remdesivir","authors":"Luiz Eduardo Ceccon Calil de Assumpção ,&nbsp;Bruno Graciano Ponce Romeo ,&nbsp;João Carlos de Campos Guerra ,&nbsp;Luis Fernando Aranha Camargo ,&nbsp;Marcelo Akira Nagaoka ,&nbsp;Deyvid Emanuel Amgarten ,&nbsp;Erick Gustavo Dorlass ,&nbsp;Roberta Cardoso Petroni ,&nbsp;Afonso Celso Almeida Cardoso ,&nbsp;Renato de Mello Ruiz ,&nbsp;Carolina Devite Bittante ,&nbsp;Vanessa Damazio Teich ,&nbsp;João Renato Rebello Pinho ,&nbsp;André Mario Doi","doi":"10.1016/j.idcr.2025.e02199","DOIUrl":"10.1016/j.idcr.2025.e02199","url":null,"abstract":"<div><h3><em>Background</em></h3><div>There is a significant concern of the pandemic impact of SARS-CoV-2 infection in immunocompromised patients. These patients can develop long COVID-19 due to impairment of cellular and humoral immunity. On the other hand, prolonged infection can lead to mutations in the SARS CoV-2 genome that can impact on the resistance to antiviral therapy. Remdesivir cases have been reported in patients receiving antiviral drug treatment.</div></div><div><h3>Case presentation</h3><div>A 46-year-old male with previous mantle cell lymphoma resolved by autologous bone marrow transplantation without other comorbidities had SARS-CoV-2 detected in February 2022 and received the recommended antiviral treatment with Remdesivir. COVID-19 evolved in four months with worsening of the symptoms, despite an initial rapid improvements and high RT-PCR Ct values. The patient was relieved from hospital care stable and well but still maintaining positive test results.</div></div><div><h3>Conclusions</h3><div>the patient presented prolonged COVID-19 with persistence of virus detected by RT-PCR for several months. The strain sequenced presented a mutation different from all reported previously. Although it was no possible to sequence the initial strain without these mutations, our data suggests that immunocompromised patient with prolonged COVID-19 may serve as reservoir for strains of SARS-CoV-2 with resistant components in his genome.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02199"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143697278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eikenella corrodens in a patient with septic arthritis: A case report","authors":"Marrigje Jacoba Kreuger ,&nbsp;Anteneh Eshetu ,&nbsp;Ebenezer Gezahegn Fanta","doi":"10.1016/j.idcr.2025.e02222","DOIUrl":"10.1016/j.idcr.2025.e02222","url":null,"abstract":"<div><div><em>Eikenella corrodens</em>, a Gram-negative bacterium, is typically associated with fight-bite injuries and, in rare cases, with infective endocarditis. Infection may arise either through direct inoculation or through invasion of oral mucosa with subsequent bacteraemia. This bacterium is an unusual cause of infection in immunocompetent patients without direct injury. There are no studies published from Ethiopia on identification of <em>Eikenella corrodens</em> in humans. In this case report, we describe a patient with a septic arthritis and tibia bone abscess where <em>Eikenella corrodens</em> was identified. Recognition of septic arthritis was delayed and identification of the microorganism was challenging. This influenced the choice and duration of treatment and has likely affected the patient’s outcome. This case report emphasizes the significance of recognizing rare pathogens in complex cases, considering slow-growing microorganisms and anticipating treatment challenges when uncommon microorganisms are involved.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02222"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143820823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translucent colonies and gram-negative diplococci: Meningococcal pneumonia masquerading as Moraxella pneumonia","authors":"Ryuichi Minoda Sada","doi":"10.1016/j.idcr.2025.e02265","DOIUrl":"10.1016/j.idcr.2025.e02265","url":null,"abstract":"","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02265"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143941174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Minocycline-induced hyperpigmentation: Importance of early diagnosis” [ID Cases 34 (2023) e01901]","authors":"Tomohide Okinaka ,&nbsp;Kento Fukumitsu ,&nbsp;Nozomi Okamura ,&nbsp;Liya Wang ,&nbsp;Yoshihiro Ohishi ,&nbsp;Yoshiko Miyazaki ,&nbsp;Takashi Matono","doi":"10.1016/j.idcr.2024.e02129","DOIUrl":"10.1016/j.idcr.2024.e02129","url":null,"abstract":"","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02129"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144230303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Elizabethkingia Anophelis and Miricola in El Salvador: Report of the first three cases","authors":"Flor Castro-Rodriguez ,&nbsp;Carmen Albanez-Ayala ,&nbsp;Yakdiel Rodriguez-Gallo ,&nbsp;Rodrigo Amaya-Reyes ,&nbsp;Alfredo Merino-Luna","doi":"10.1016/j.idcr.2025.e02272","DOIUrl":"10.1016/j.idcr.2025.e02272","url":null,"abstract":"<div><div><em>Elizabethkingia spp.</em> is an emerging bacterium posing a global threat, causing potentially fatal infections often associated with high mortality rates. This study reports the first three patients with <em>Elizabethkingia Anophelis</em> and <em>Miricola</em> infections in El Salvador, Central America. Cultures conducted using MALDI-TOF MS Biotyper technology confirmed the presence of these pathogens. The method of infection in the patients is still unclear, although in one of them, it could have been through nosocomial transmission. In the other two patients, transmission through mosquitoes, endemic to the region, is not ruled out. Efforts to prevent and enhance the understanding of infections caused by <em>Elizabethkingia spp.,</em> as well as to restrict their spread, must be effectively intensified in the face of this new challenge.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02272"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144147092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retropharyngeal abscess caused by Streptococcus agalactiae: A case report and literature review","authors":"Naoko Iwai-Kumashiro,&nbsp;Masamitsu Kono,&nbsp;Yohei Morita,&nbsp;Shunji Tamagawa,&nbsp;Muneki Hotomi","doi":"10.1016/j.idcr.2025.e02276","DOIUrl":"10.1016/j.idcr.2025.e02276","url":null,"abstract":"<div><div>A previously healthy 79-year-old man who developed a retropharyngeal abscess secondary to Group B <em>Streptococcus</em> (GBS) infections is reported. Comprehensive imaging evaluation revealed a retropharyngeal abscess due to pyogenic spondylitis was made, which progressed to an epidural abscess and descending necrotizing mediastinitis. Successful treatment with surgical drainage and antimicrobial chemotherapy suggests that with prompt diagnosis and appropriate management, outcomes can be favorable even in severe presentations. The pathogenesis of invasive GBS infection in the elderly is multifactorial. Immune senescence and bacterial translocation may play an important role. This case report highlights an important shift in the microbiological landscape of invasive GBS infections, particularly in adults.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02276"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144222422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous rupture of a subcapsular hepatic hematoma due to fascioliasis: A rare parasitic complication managed conservatively – Case report","authors":"José Caballero-Alvarado ,&nbsp;Ana Tapia-Beltrán ,&nbsp;Paula Tirado-López ,&nbsp;Víctor Lau-Torres ,&nbsp;Carlos Zavaleta-Corvera","doi":"10.1016/j.idcr.2025.e02287","DOIUrl":"10.1016/j.idcr.2025.e02287","url":null,"abstract":"<div><h3>Background</h3><div>Fascioliasis is a parasitic zoonosis endemic to South America, caused by <em>Fasciola hepatica</em>. During the acute migratory phase, the parasite affects the liver parenchyma, potentially leading to complications such as abscesses or necrosis. However, spontaneous rupture of a hepatic subcapsular hematoma related to <em>Fasciola hepatica</em> infection is exceptionally rare and poorly documented in the literature. The aim of the present study is to report an unusual presentation of <em>Fasciola hepatica</em> infection and to highlight the diagnostic relevance of parasitic etiologies in patients with eosinophilia and atypical hepatic imaging findings in endemic areas or in patients with travel history.</div></div><div><h3>Case presentation</h3><div>A 38-year-old man from a rural area endemic for Fasciola hepatica presented with progressive right upper quadrant abdominal pain, dizziness, and fatigue. Physical examination revealed pallor and localized tenderness. Laboratory studies showed severe normocytic anemia (hemoglobin: 6.8 g/dL) and marked eosinophilia (2600 cells/μL). Abdominal CT revealed a large subcapsular hepatic hematoma with hemoperitoneum. Given the eosinophilia and epidemiological background, a parasitic cause was suspected. Western blot serology confirmed <em>Fasciola hepatica</em> infection. Liver function tests were normal, and there was no history of trauma or coagulopathy. The patient received conservative management, including fluid resuscitation, blood transfusion, and antiparasitic treatment with triclabendazole (10 mg/kg, repeated after 12 h). Follow-up imaging demonstrated gradual hematoma resolution. He was discharged after 10 days in stable condition and remained asymptomatic during outpatient follow-up.</div></div><div><h3>Conclusion</h3><div>This case underscores the need to consider parasitic infections in the differential diagnosis of unexplained hepatic lesions with eosinophilia, especially in endemic areas. Early recognition enables effective non-surgical management.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02287"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144306154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rapidly progressive case of tuberculous pleurisy and pericarditis in a patient with non-small cell lung cancer that developed one month after receiving pembrolizumab monotherapy","authors":"Saori Ikeda ,&nbsp;Kageaki Watanabe ,&nbsp;Kazuhito Misawa ,&nbsp;Noriyo Yanagawa ,&nbsp;Yukio Hosomi","doi":"10.1016/j.idcr.2025.e02234","DOIUrl":"10.1016/j.idcr.2025.e02234","url":null,"abstract":"<div><div>We report a rapidly progressive case of tuberculous pleurisy and pericarditis. A 59-year-old, male patient with non-small-cell lung cancer commenced pembrolizumab monotherapy one month before but soon thereafter had fevers and dyspnea. Radiography revealed increased right pleural effusion, novel left pleural effusion and cardiomegaly, which had been absent 10 days earlier when a reduction in the target lesion was confirmed. Computed tomography revealed the presence of pericardial fluid. Analysis of the pleural effusion didn’t detect malignancy; however, the culture was positive for tuberculosis. It suggests that pembrolizumab may have induced severe inflammation leading to the rapid progression of the disease.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02234"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Autoimmune encephalitis associated with anti-SOX1 autoantibodies in COVID-19: A case report","authors":"Peter Sabaka ,&nbsp;Gabriela Timárová ,&nbsp;Mohammad Dababseh ,&nbsp;Eliška Marešová ,&nbsp;Igor Straka","doi":"10.1016/j.idcr.2025.e02220","DOIUrl":"10.1016/j.idcr.2025.e02220","url":null,"abstract":"<div><div>Coronavirus disease 2019 (COVID-19) might be complicated by various non-respiratory conditions, including encephalitis. Encephalitis in COVID-19 represents a heterogenous group of diseases with variable aetiology. Autoimmune encephalitis (AIE) is the least common but one of the most severe causes of encephalopathy in COVID-19. AIE is a rare disease that is associated with different types of autoantibodies mostly directed against various neuronal antigens. Anti-Sry-like high mobility group box (SOX1) autoantibodies have been described in various clinical conditions, including Lambert-Eaton myasthenic syndrome, paraneoplastic cerebellar degeneration and rare cases of paraneoplastic AIE. We present the case of 28-year-old female patient with COVID-19 confirmed by the polymerase chain reaction (PCR) test. She was admitted with fever, headache, disorientation and new-onset refractory status epilepticus. Computed tomography and magnetic resonance imaging of the brain were unremarkable. Cerebrospinal fluid analysis showed pleocytosis, an increased total protein concentration and increased albumin and immunoglobulin G. Electroencephalography revealed findings suggestive of AIE. Serologic examination of antineuronal antibodies showed anti-SOX1 autoantibodies. A course of parenteral methylprednisolone and intravenous immunoglobulin led to rapid clinical improvement. The patient was discharged free of seizures as well as neurologic and psychiatric symptoms. After discharge, an oncologic screening was performed and ruled out a paraneoplastic aetiology.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02220"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143855842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare neurological complication of dengue: Guillain-Barré Syndrome in a dengue fever patient","authors":"Ibrahim Nagmeldin Hassan ,&nbsp;Siddig Yaqub ,&nbsp;Mohamed Ibrahim ,&nbsp;Ghada Aljaili ,&nbsp;Nagmeldin Abuassa","doi":"10.1016/j.idcr.2025.e02160","DOIUrl":"10.1016/j.idcr.2025.e02160","url":null,"abstract":"<div><h3>Background</h3><div>Dengue fever is a common viral illness in tropical and subtropical regions, typically presenting with fever, myalgia, and hemorrhagic symptoms. While neurological complications are rare, Guillain-Barré Syndrome (GBS) is a known but uncommon sequelae of viral infections, including dengue.</div></div><div><h3>Case presentation</h3><div>We report the case of a previously healthy 32-year-old male who developed acute flaccid paralysis secondary to GBS following a dengue fever infection. The patient initially presented with classic dengue symptoms—fever, severe headache, retro-orbital pain, and myalgia. Following resolution of the acute dengue phase, he developed ascending muscle weakness, areflexia, and numbness in both legs. Electromyography confirmed a diagnosis of GBS, and cerebrospinal fluid analysis revealed albuminocytologic dissociation. The patient was treated with intravenous immunoglobulin (IVIG), leading to significant clinical improvement, with gradual recovery of motor function.</div></div><div><h3>Discussion</h3><div>This case highlights the rare but significant neurological complication of GBS following dengue fever. Clinicians should maintain a high index of suspicion for GBS in patients recovering from dengue, especially in endemic regions. Early diagnosis and treatment with IVIG or plasmapheresis are critical for improving outcomes in these patients.</div></div><div><h3>Conclusion</h3><div>Dengue fever can lead to severe neurological sequelae such as GBS, and early recognition and intervention can prevent long-term disability. This case underscores the need for vigilance in identifying such complications in patients recovering from viral infections.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02160"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}