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Acute gonococcal urethritis 急性淋球菌性尿道炎。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02130
H. Shatikkulamin , Chandana Shajil
{"title":"Acute gonococcal urethritis","authors":"H. Shatikkulamin ,&nbsp;Chandana Shajil","doi":"10.1016/j.idcr.2024.e02130","DOIUrl":"10.1016/j.idcr.2024.e02130","url":null,"abstract":"<div><div>Gonococcal urethritis is a sexually transmitted infection caused by obligate gram-negative diplococci, Neisseria gonorrhoeae. In a patient complaining of dysuria and urethral discharge, the diagnosis is typically confirmed by identifying the bacteria in mucosal secretions. Inadequately treated or untreated cases are at a risk of developing epididymo-orchitis, prostatitis and serious complications like disseminated gonococcal infection, meningitis, and endocarditis.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02130"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of acute community-acquired pneumonia caused by Tropheryma whipplei in pregnant woman without predisposing medical conditions 一例由 Tropheryma whipplei 引起的急性社区获得性肺炎病例，孕妇无诱发疾病。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02123
Hao Wang , Hongna Yang
{"title":"A case of acute community-acquired pneumonia caused by Tropheryma whipplei in pregnant woman without predisposing medical conditions","authors":"Hao Wang ,&nbsp;Hongna Yang","doi":"10.1016/j.idcr.2024.e02123","DOIUrl":"10.1016/j.idcr.2024.e02123","url":null,"abstract":"<div><div><em>Tropheryma whipplei</em> (<em>T. whipplei</em>) is extensively known as the etiological bacterium of Whipple’s disease (WD). Here, we reported a case of community-acquired pneumonia caused by <em>T. whipplei</em> in a young pregnant woman without predisposing medical conditions. This case indicated that <em>T. whipplei</em> might be also transmitted via respiratory droplet.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02123"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11683261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142907780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The cruciality of increasing index of suspicion for atypical Bartonella henselae in pediatric patients: A case series 儿童非典型亨selae巴尔通体怀疑指数增加的重要性：一个病例系列
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02192
Victoria Vazquez , Lorraine Bermudez-Rivera , Arino Neto , Vanessa Perez , Adriana Cadilla , Linette Sande
{"title":"The cruciality of increasing index of suspicion for atypical Bartonella henselae in pediatric patients: A case series","authors":"Victoria Vazquez ,&nbsp;Lorraine Bermudez-Rivera ,&nbsp;Arino Neto ,&nbsp;Vanessa Perez ,&nbsp;Adriana Cadilla ,&nbsp;Linette Sande","doi":"10.1016/j.idcr.2025.e02192","DOIUrl":"10.1016/j.idcr.2025.e02192","url":null,"abstract":"<div><div><em>Bartonella henselae</em>, a gram-negative rod, is the etiologic agent of cat scratch disease, which may manifest as a self-limiting local infection or as an atypical, invasive disease. Establishing <em>B. henselae</em> as the causative organism can be challenging as it is a fastidious organism that does not grow on traditional media. Diagnosis is generally performed with serology, which has variable turnaround times, or microbial cell-free DNA (mcfDNA) sequencing, which has a high cost. Therefore, a high index of suspicion is necessary for timely diagnosis and management of these invasive infections. We depict a case series of nine atypical Bartonella infections in children. By highlighting these presentations, their diagnostic testing, and treatment, we emphasize the significance of an elevated index of suspicion of atypical bartonellosis for accurate diagnosis and timely antibiotic management. Our invasive Bartonella cases entail culture-negative subacute endocarditis, osteomyelitis, neuroretinitis, encephalitis, hepatosplenic disease, and lymphadenopathy with splenic involvement.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02192"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143593429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of recurrent Candida glabrata fungemia and successful treatment with rezafungin 一例复发性念珠菌菌血症和雷扎芬净的成功治疗
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02233
Divya Chandramohan , Samantha Aguilar , Gerard Gawrys , Nathan P. Wiederhold , Kristi Traugott , Thomas F. Patterson
{"title":"A case of recurrent Candida glabrata fungemia and successful treatment with rezafungin","authors":"Divya Chandramohan ,&nbsp;Samantha Aguilar ,&nbsp;Gerard Gawrys ,&nbsp;Nathan P. Wiederhold ,&nbsp;Kristi Traugott ,&nbsp;Thomas F. Patterson","doi":"10.1016/j.idcr.2025.e02233","DOIUrl":"10.1016/j.idcr.2025.e02233","url":null,"abstract":"<div><div>Antifungal resistance in <em>Candida glabrata</em> can develop to different classes of drugs, including the azoles and echinocandins. This organism is known to cause infective endocarditis with a particular predilection for prosthetic valves. Herein we present a case of recurrent fungemia with <em>C. glabrata</em> in a middle-aged woman with Tetralogy of Fallot who had a right ventricle to pulmonary artery conduit, and a transcatheter pulmonary valve replacement in the past. Her isolate showed increasing minimum inhibitory concentrations (MIC) to various antifungals with higher MICs to azoles, including resistance to fluconazole, resulting in limited treatment options. She had affliction of her prosthetic pulmonic valve with <em>C. glabrata</em> and was treated with the second-generation echinocandin, rezafungin, for six months. This case illustrates the tolerability profile of long-term treatment with rezafungin.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02233"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143859505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two patients with endometriosis require peripregnancy surgical treatment for pelvic abscesses after egg collection and embryo transfer 2例子宫内膜异位症患者在取卵和胚胎移植后需要围妊娠期手术治疗盆腔脓肿
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02184
Tatsunori Shiraishi , Masafumi Toyoshima , Masao Ichikawa , Shigeo Akira
{"title":"Two patients with endometriosis require peripregnancy surgical treatment for pelvic abscesses after egg collection and embryo transfer","authors":"Tatsunori Shiraishi ,&nbsp;Masafumi Toyoshima ,&nbsp;Masao Ichikawa ,&nbsp;Shigeo Akira","doi":"10.1016/j.idcr.2025.e02184","DOIUrl":"10.1016/j.idcr.2025.e02184","url":null,"abstract":"<div><div>Assisted reproductive technology procedures infrequently cause pelvic abscesses, but the risk is higher in patients with endometriosis. If antibiotic treatment of a pelvic abscess is unsuccessful, surgery is required—even during pregnancy. We report two patients with endometriosis who suffered from pelvic abscesses formed after egg collection and embryo transfer. Patient 1 underwent laparoscopic resection of the left adnexa and right ovarian cystectomy after diagnosis of the implantation failure. Surgical findings showed severe adhesions in the pelvis due to endometriosis. Patient 2 underwent open drainage surgery at 11 weeks of pregnancy due to pan-peritonitis caused by a pelvic abscess. The patient delivered at 36 weeks of gestation. We conclude that egg collection and embryo transfer in patients with endometriosis confers a high risk for pelvic infection. An accurate diagnosis and appropriate treatment, including surgery, are mandatory in case of severe pelvic abscesses during pregnancy to save both mother and fetus.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02184"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143386998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Blasto-ing through the chest wall: Empyema necessitans due to pulmonary blastomycosis 胸壁破胚：肺芽菌病引起的必要脓胸
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02185
Cameron G. Gmehlin , Nicholas P. Bergeron , Vaishnavi Ramesh , Haris Akhtar , Zelalem Temesgen
{"title":"Blasto-ing through the chest wall: Empyema necessitans due to pulmonary blastomycosis","authors":"Cameron G. Gmehlin ,&nbsp;Nicholas P. Bergeron ,&nbsp;Vaishnavi Ramesh ,&nbsp;Haris Akhtar ,&nbsp;Zelalem Temesgen","doi":"10.1016/j.idcr.2025.e02185","DOIUrl":"10.1016/j.idcr.2025.e02185","url":null,"abstract":"<div><div>Empyema necessitans is a rare complication of empyema and often associated with chronic, untreated infections. Here we report a case of a 28-year-old male who presented with cough, fever, pleuritic chest pain, and left chest wall mass who was found to have empyema necessitans caused by <em>Blastomycosis dermatiditis</em>. He was neither immunocompromised nor had exposures to soil or freshwater sources. Empyema necessitans caused by Blastomyces is rare, with only three other case reports published in the literature. We write to raise awareness of this phenomenon and highlight the importance of maintaining strong clinical suspicion for fungal etiologies of chronic constitutional and pulmonary symptoms, especially when unresponsive to empiric antibiotics.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02185"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143396274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intracellular but not undetectable: A case of Francisella tularensis pericarditis 细胞内但未检出：土拉菌性心包炎1例。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02145
Nicholas P. Bergeron , Cameron G. Gmehlin , Haris Akhtar , Kemar O. Barrett , Sara S. Inglis , Lawrence J. Sinak , Charanjit S. Rihal , Daniel C. DeSimone
{"title":"Intracellular but not undetectable: A case of Francisella tularensis pericarditis","authors":"Nicholas P. Bergeron ,&nbsp;Cameron G. Gmehlin ,&nbsp;Haris Akhtar ,&nbsp;Kemar O. Barrett ,&nbsp;Sara S. Inglis ,&nbsp;Lawrence J. Sinak ,&nbsp;Charanjit S. Rihal ,&nbsp;Daniel C. DeSimone","doi":"10.1016/j.idcr.2024.e02145","DOIUrl":"10.1016/j.idcr.2024.e02145","url":null,"abstract":"<div><div><em>Francisella tularensis</em> is a facultatively intracellular, gram-negative bacillus and a rare cause of infection in the United States. We report a case of a 45-year-old male who presented with ongoing fever, shortness of breath, and was found to have a pericardial effusion and pulmonic infiltrates due to <em>F. tularensis</em>. Though tularemia is classically associated with rabbits and rodents, we note the patient in our case had no clear infectious exposure. Tularemia pericarditis is extremely rare, and this will be only the second report since 1957. We highlight the possible benefits of microbial cell-free DNA next generation sequencing when infection is suspected without obvious cause to reduce the morbidity and mortality from underlying infection.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02145"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143048154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A fatal case of disseminated Cladophialophora bantiana infection in a renal transplant recipient 肾移植受者弥散性班提亚氏克氏菌感染1例死亡。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02128
Kali Maniam , Rabeeya Sabzwari , Daniel Carlsen
{"title":"A fatal case of disseminated Cladophialophora bantiana infection in a renal transplant recipient","authors":"Kali Maniam ,&nbsp;Rabeeya Sabzwari ,&nbsp;Daniel Carlsen","doi":"10.1016/j.idcr.2024.e02128","DOIUrl":"10.1016/j.idcr.2024.e02128","url":null,"abstract":"<div><div>Dematiaceous molds often cause noninvasive disease but have the potential to cause disseminated infection, particularly in immunosuppressed hosts. <em>Cladophialophora bantiana</em> is the most neurotropic of dematiaceous molds and is associated with brain abscesses, but disseminated infection is quite rare. Here we present a case of disseminated <em>C. bantiana</em> in a 67-year-old renal transplant recipient with multifocal soft tissue, bone and presumed central nervous system involvement. <em>C. bantiana</em> infections have been associated with significant mortality and our patient had progression of his disease despite intensive dual antifungal therapy with close therapeutic drug monitoring. There was a delay in diagnosis and initiation of antifungal therapy as the multifocal disease was presumed to represent a malignant process. This case review highlights the importance of having a high index of suspicion for disseminated fungal infection in immunocompromised patients and the need for tissue biopsy to aid in the prompt and timely diagnosis and initiation of empiric antifungal therapy, with concomitant surgical management whenever possible to improve patient outcomes.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02128"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11728889/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142979898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary hydatid cyst misdiagnosed as lung cancer 肺水瘤囊肿被误诊为肺癌。
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02133
Houssem Messaoudi , Imen Ben Ismail , Wafa Ragmoun , Mokhles Lajmi , Bochra Zayène , Islam Mejri , Saber Hachicha
{"title":"Pulmonary hydatid cyst misdiagnosed as lung cancer","authors":"Houssem Messaoudi ,&nbsp;Imen Ben Ismail ,&nbsp;Wafa Ragmoun ,&nbsp;Mokhles Lajmi ,&nbsp;Bochra Zayène ,&nbsp;Islam Mejri ,&nbsp;Saber Hachicha","doi":"10.1016/j.idcr.2024.e02133","DOIUrl":"10.1016/j.idcr.2024.e02133","url":null,"abstract":"<div><div>Hydatid disease is endemic in Tunisia. Whereas uncomplicated pulmonary hydatid cysts are easily diagnosed on radiological findings, complicated and atypical forms may be misdiagnosed and confused with other pulmonary lesions, mainly lung malignancies. We report a case of a 47-year-old woman, who presented with a 3-month history of hemoptysis. Physical examination was normal. Chest x-ray and CT scan of the chest revealed a mass with speculated margins and central necrosis, located in the apical segment of the right lower lobe moderately contrast-enhanced. The scan guided biopsy showed inflammatory pulmonary parenchyma with no signs of malignancy. Fiberoptic bronchoscopy revealed significant bleeding from the superior segmental bronchus of right lower lobe. Pathology examination of the bronchial aspiration revealed a suggestive aspect of malignant cells. Regarding those findings, lung carcinoma was highly suspected and the importance of hemoptysis motivated an urgent hemostasis lobectomy. The patient underwent a right lower lobectomy with radical lymph node dissection via a right posterolateral thoracotomy. Histological examination showed a laminated membrane lined by a proligerous membrane made up of a layer of eosinophilic cells confirming the diagnosis of pulmonary hydatid cyst. It should be kept in mind that pulmonary hydatid disease can clinically, radiologically mimic lung cancer. Exceptionally, even cytology can lead to a diagnosis pitfall.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02133"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11729004/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142980026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hemophagocytic lymphohistiocytosis in a neonate with enterovirus infection: Case report and literature review 肠道病毒感染新生儿嗜血细胞淋巴组织细胞增多症：病例报告和文献综述
IF 1.1
IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02177
Hua Hu , Shukun Yu , Jing Zhang , Hongping Zhang
{"title":"Hemophagocytic lymphohistiocytosis in a neonate with enterovirus infection: Case report and literature review","authors":"Hua Hu ,&nbsp;Shukun Yu ,&nbsp;Jing Zhang ,&nbsp;Hongping Zhang","doi":"10.1016/j.idcr.2025.e02177","DOIUrl":"10.1016/j.idcr.2025.e02177","url":null,"abstract":"<div><div>Viruses are the most common organisms causing hemophagocytic lymphohistiocytosis (HLH), and enterovirus infection is the most frequently diagnosed virus infection in the newborn period. However, in recent years, there have been relatively few reports of enterovirus infection in Chinese neonates complicated by HLH. Here, we describe a female preterm infant who contracted echovirus 11 at day 4 and rapidly developed sepsis during the following three days, along with fever, lethargy, disseminated intravascular coagulation (DIC), and sepsis. She was ultimately identified as having echovirus 11 complicated by HLH. This report will contribute to increasing public awareness of the link between HLH and echo 11 infection, which can aid in early identification and treatment.</div><div><strong>What’s New:</strong> We reported female preterm infant who contracted echovirus 11 at day 4 and rapidly developed sepsis during the following three days, it was the first report from central China that we are aware of.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02177"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143593428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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