IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02150

Hidenori Nakagawa , Akari Takagi , Takahiro Mitsueda , Michinori Shirano

引用次数: 0

Coinfection of Herpes Simplex virus 2 and Mycobacterium chelonae in acute hydrops associated with keratoconus: A case report

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02176

Pedro Marques-Couto , Ana Gama-Castro , Teresa Carvalho , Rodrigo Vilares-Morgado , João Pinheiro-Costa , Dolores Pinheiro , Ana Maria Cunha

{"title":"Coinfection of Herpes Simplex virus 2 and Mycobacterium chelonae in acute hydrops associated with keratoconus: A case report","authors":"Pedro Marques-Couto , Ana Gama-Castro , Teresa Carvalho , Rodrigo Vilares-Morgado , João Pinheiro-Costa , Dolores Pinheiro , Ana Maria Cunha","doi":"10.1016/j.idcr.2025.e02176","DOIUrl":"10.1016/j.idcr.2025.e02176","url":null,"abstract":"<div><h3>Purpose</h3><div>Acute hydrops is a characteristic complication of corneal ectatic diseases. While <em>Mycobacterium chelonae</em> is known to cause various ophthalmic infections, most commonly following surgery, there are no reported cases of infection by this microorganism in the context of acute hydrops, nor concurrent with <em>Herpes Simplex virus 2</em> infection.</div></div><div><h3>Observations</h3><div>A 33-year-old Portuguese woman of Caucasian ethnicity with a history of keratoconus presented with a red eye and ocular discomfort in the right eye at the Ophthalmology Emergency Department. Initial examination revealed acute hydrops with no epithelial defects nor signs of infection. Posteriorly, she developed dendritic epithelial lesions suggestive of <em>Herpes Simplex</em> virus infection. These lesions progressed, leading to a central corneal infiltrate and descemetocele. Due to perforation of the descemetocele, a tectonic penetrating keratoplasty was successfully performed, and coinfection of <em>Herpes Simplex virus 2</em> and <em>Mycobacterium chelonae</em> was later confirmed through microbiological examination.</div></div><div><h3>Conclusions and importance</h3><div>This is the first reported case of corneal coinfection with <em>Herpes Simplex virus 2</em> and <em>Mycobacterium chelonae</em> in the setting of acute hydrops. The combination of corneal edema, previous viral infection, and prolonged corticosteroid use likely created a “perfect storm” scenario, predisposing the patient to this unusual coinfection. Our findings highlight the need for heightened awareness of atypical infections in patients with acute hydrops and suggest that such complications may alter corneal barrier function. This case contributes to the understanding of complex interactions between corneal conditions and microbial infections.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02176"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143157746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A unique case of herpetic keratitis manifesting as recurrent preseptal cellulitis

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02187

Emily Miller , Maxwell Ward , Tasaduq Fazili , Ekta Bansal

引用次数: 0

Ictal vomiting as an unusual presentation of herpes simplex encephalitis ‐ Pathophysiological and therapeutic perspectives

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02186

Hosna Elshony , Abdelrahman Idris , Abdulaziz Al-Ghamdi , Rakan Almuhanna , Waleed Amsaib M. Ahmed

{"title":"Ictal vomiting as an unusual presentation of herpes simplex encephalitis ‐ Pathophysiological and therapeutic perspectives","authors":"Hosna Elshony , Abdelrahman Idris , Abdulaziz Al-Ghamdi , Rakan Almuhanna , Waleed Amsaib M. Ahmed","doi":"10.1016/j.idcr.2025.e02186","DOIUrl":"10.1016/j.idcr.2025.e02186","url":null,"abstract":"<div><h3>Introduction</h3><div>Herpes Simplex Encephalitis (HSE) is a formidable neurological infection that is often challenging to diagnose owing to its diverse clinical manifestations. This case report details the clinical odyssey of a sixty-year-old female with diabetes, hypothyroidism, and hypertension, who presented with fever, vomiting, and evolving neurological symptoms.</div></div><div><h3>Case Presentation</h3><div>The patient's initial admission failed to yield a diagnosis, and her condition worsened, marked by behavioral changes, cognitive decline, and focal seizures. Neuroimaging revealed characteristic findings, confirming non-hemorrhagic herpetic encephalitis. Despite antiviral and antiepileptic therapy, persistent vomiting prompted further investigations, uncovering infrequent right temporal sharp waves on EEG, leading to a diagnosis of \"ictus emiticus.\"</div></div><div><h3>Conclusion</h3><div>This case of Herpes Simplex Encephalitis (HSE) underscores the diverse clinical spectrum and challenges in management. The patient's atypical presentation underscores the importance of considering HSE in patients with fever and unexplained persistent vomiting for early diagnosis and better prognosis.</div><div>Diagnostic tools (neuroimaging, cerebrospinal fluid analysis, and electroencephalography) confirmed HSE involvement in the right temporal lobe, emphasizing the strong association between HSV encephalitis and seizures, which can be explained by various mechanisms.</div><div>Timely antiviral therapy and tailored antiepileptic strategies led to gradual clinical improvement, showcasing the potential of valproate beyond antiepileptic use.</div><div>This case prompts further exploration into HSE's pathophysiology and treatment. It emphasizes individualized patient care and vigilance for potential post-resolution sequelae, contributing to our evolving understanding of HSE.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02186"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143386997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Failure of Gallium-68 citrate to detect large, enhancing, intracerebral central nervous system tuberculomas: A cautionary tale

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02155

Selwyn Selva Kumar , Adrian Keith Noronha , Julie Hephzibah , Harshad Arvind Vanjare , Abi Manesh

引用次数: 0

Fusobacterium necrophorum associated with pelvic infections: A case series and literature review 与盆腔感染相关的坏死杆菌：病例系列和文献综述

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02190

Manasa Brown , Sabrina Imam , Jade Pagkas-Bather

引用次数: 0

Neurobrucellosis manifested by recurrent aseptic meningitis: A case report

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02193

Reza Razaghi , Fatemeh Kourkinejad_Gharaei , Forough Faroughi

{"title":"Neurobrucellosis manifested by recurrent aseptic meningitis: A case report","authors":"Reza Razaghi , Fatemeh Kourkinejad_Gharaei , Forough Faroughi","doi":"10.1016/j.idcr.2025.e02193","DOIUrl":"10.1016/j.idcr.2025.e02193","url":null,"abstract":"<div><div>Brucellosis is an endemic zoonotic disease in LMIC countries. Neurobrucellosis is a rare and serious complication that affects 3–5 % of cases worldwide. We report the successful treatment of a 31-year-old woman who presented with a chief complaint of headache and nausea. Headache was started six months before admission in the frontal and occipital area with radiation to the neck. The patient hospitalized three times within last six months with diagnosis of aseptic meningitis. Brucellosis, tuberculosis, and syphilis tests and CSF fluid analysis were requested. Neutrophilia and pleocytosis in CSF fluid. Analysis of CSF fluid for cytology and PCR test for HSV-1&2 was negative. Rheumatologic tests for SLE, Behcet's disease and sarcoidosis were also negative. Test results was as follow: Wright: 1/320, Coombs Wright: 1/640, 2ME: 1/160, Brucella IgG: 25(Positive). According to the test results, combined treatment with rifampin, Co-trimoxazole, and ceftriaxone was performed for neurobrucellosis for nine months. Considering the endemic prevalence of brucellosis in this region, the rare manifestations of this disease should be considered.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"40 ","pages":"Article e02193"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143579986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Haemophilus Influenzae Type F as a rare cause of septic arthritis

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02204

Charles E. McCafferty , Luke McKinnon , Tristan Rappo

引用次数: 0

Fever for days: A challenging case of dalbavancin-induced fever

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2024.e02138

Mohamed A. Almahal , Claire Wan , Benjamin Albrecht , Sarah Green , Ahmed Babiker

引用次数: 0

Ceftazidime-resistance in pediatric melioidosis: A case report and literature review

IF 1.1

IDCases Pub Date : 2025-01-01 DOI: 10.1016/j.idcr.2025.e02149

Tonnii Loong-Loong Sia , Charles Dekun Lai , Kamilah Manan , Fu-Lung Khiu , Siti Zakiyyah Bakhtiar , Yek-Kee Chor , Su-Lin Chien , Lee-See Tan , Mong-How Ooi , Anand Mohan

{"title":"Ceftazidime-resistance in pediatric melioidosis: A case report and literature review","authors":"Tonnii Loong-Loong Sia , Charles Dekun Lai , Kamilah Manan , Fu-Lung Khiu , Siti Zakiyyah Bakhtiar , Yek-Kee Chor , Su-Lin Chien , Lee-See Tan , Mong-How Ooi , Anand Mohan","doi":"10.1016/j.idcr.2025.e02149","DOIUrl":"10.1016/j.idcr.2025.e02149","url":null,"abstract":"<div><div>We report a first case of ceftazidime-resistant pediatric melioidosis involving a previously healthy seven-year-old boy who presented with right lobar pneumonia complicated with a 5-cm lung abscess. Ceftazidime was initiated on Day-6 of admission when <em>Burkholderia pseudomallei</em> (ceftazidime-susceptible, minimum inhibitory concentration [MIC] 1.0 mcg/mL) was isolated from blood. Despite ceftazidime therapy at the recommended dosage, he developed fulminant septic shock and respiratory failure on Day-18 of hospitalization, requiring invasive ventilation, hemodynamic support, and continuous renal replacement therapy. His antibiotic was empirically escalated to meropenem; ceftazidime-resistant <em>B. pseudomallei</em> (MIC 32 mcg/mL) was subsequently isolated from blood and endotracheal secretions<em>.</em> He improved after two weeks of intensive care and was discharged well after two months of hospitalization. Our literature review on ceftazidime-resistant <em>B. pseudomallei</em> infection indicates that acquired resistance is a rare but potentially lethal treatment-related complication. All melioidosis patients should be carefully monitored during treatment with ceftazidime (or other β-lactams) for the development of antimicrobial resistance.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"39 ","pages":"Article e02149"},"PeriodicalIF":1.1,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773197/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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