IDCases最新文献

{"title":"Skin abscess caused by Trueperella bernardiae: Case report and literature review","authors":"Rasha M. Abddelgader ,&nbsp;Sarvenaz Karamooz ,&nbsp;Hosoon Choi ,&nbsp;Munok Hwang ,&nbsp;Chetan Jinadatha ,&nbsp;Dhammika H. Navarathna","doi":"10.1016/j.idcr.2024.e01985","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01985","url":null,"abstract":"<div><p>We investigated a skin abscess caused by <em>Trueperella bernardiae</em> in a patient with comorbidities. Initial empirical therapy with Clindamycin did not yield a response, and follow-up culture revealed the presence of <em>T. bernardiae</em> through MALDI-TOF and NGS. Since no CLSI or FDA breakpoints have been published for this strain, resistant gene screening of the genetic sequence showed the presence of the erm(X) gene (with 95 % identity). This gene confers resistance to erythromycin, clindamycin, lincomycin, pristinamycin, quinupristin, and virginiamycin. Subsequent therapy with oral amoxicillin/clavulanate led to complete healing.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01985"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000611/pdfft?md5=ef2e8b2146d0e0ecb619af5b3ec71846&pid=1-s2.0-S2214250924000611-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141068249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circulating microaggregates as biomarkers for the Post‐COVID syndrome","authors":"M. Hermann ,&nbsp;C. Lisch ,&nbsp;R. Gerth ,&nbsp;G. Wick ,&nbsp;D. Fries ,&nbsp;N. Wick","doi":"10.1016/j.idcr.2024.e02000","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02000","url":null,"abstract":"<div><p>CoVID-19 can develop into Post-COVID syndrome of potentially high morbidity, with procoagulation and reactivation of dormant viral infections being hypothesized pathophysiological mechanisms. We report on a patient suffering from fatigue, post exertional malaise, pain and neurological symptoms as a consequence of the second CoVID infection. Using live confocal microscopy on native whole blood samples we detected microaggregates of thrombocytes, leukocytes and plasma proteins in peripheral blood. In addition, there was specific cellular immunological reactivity to EBV. Upon anticoagulatory and virustatic pharmacological therapy we observed dissolution of microaggregates and significant stable clinical remission. We suggest to consider circulating microaggregates as a morphological indicator of chronic post-COVID syndrome.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e02000"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000763/pdfft?md5=22b13d83bcbdda1ace49932d7034a290&pid=1-s2.0-S2214250924000763-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141095191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pyopericardium progressing to cardiac tamponade in a patient with dengue fever","authors":"Bikash Khadka ,&nbsp;Kishor Khanal ,&nbsp;Ashim Regmi ,&nbsp;Anup Ghimire ,&nbsp;Shirish KC ,&nbsp;Rohini Nepal ,&nbsp;on behalf of Doctors on Wheels","doi":"10.1016/j.idcr.2024.e01996","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e01996","url":null,"abstract":"<div><p>Pyopericardium is a rare cause of cardiac tamponade. We present a case of a dengue fever patient who presented with cellulitis of the upper limbs, later manifesting cardiac tamponade, which was fatal. Although echocardiography on admission revealed a small pericardial effusion only, it later manifested as tamponade, causing cardiogenic shock. Staphylococcus pyopericardium was found later. Early identification could be possible with bedside point-of-care ultrasonography and echocardiography. Emergent pericardiocentesis or pig tail drain placement is life saving.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"36 ","pages":"Article e01996"},"PeriodicalIF":1.5,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000726/pdfft?md5=c0e260f49ca5e2ed20ea7f22cabe140c&pid=1-s2.0-S2214250924000726-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141242258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Graft versus histoplasma disease: A case of vascular graft infection","authors":"Racha Ghoussaini ,&nbsp;Omar Abu Saleh ,&nbsp;Hussam Tabaja","doi":"10.1016/j.idcr.2024.e02013","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02013","url":null,"abstract":"<div><p><em>Histoplasma</em> vascular graft infection (VGI) is rarely reported, with only a handful of instances documented in the existing literature. Reporting <em>Histoplasma</em> VGI cases is important as they demonstrate previous treatment strategies and their outcomes. In this paper, we report a case of disseminated <em>histoplasmosis</em> with ascending aortic graft infection. Conservative therapy was attempted initially but failed, and our patient eventually required surgical graft explantation. Our case demonstrates the challenges in diagnosing and managing VGI caused by <em>Histoplasma capsulatum</em>.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02013"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000891/pdfft?md5=3dc43cec3783c41c5775b83eb11e98f8&pid=1-s2.0-S2214250924000891-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141487669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antiretroviral therapeutic drug monitoring in a patient with small bowel resection and new HIV diagnosis","authors":"Leigh Cervino Ahern ,&nbsp;Daniel Nixon ,&nbsp;Patricia Pecora Fulco","doi":"10.1016/j.idcr.2024.e02017","DOIUrl":"https://doi.org/10.1016/j.idcr.2024.e02017","url":null,"abstract":"<div><p>Antiretroviral (ARV) absorption in persons living with human immunodeficiency virus (PLWH, HIV) with short bowel syndrome is limited. We describe a case of a 28-year-old male with newly diagnosed HIV and plasmablastic lymphoma with proximal jejunostomy necessitating parenteral nutrition. ARV therapy with dolutegravir 50 mg twice daily and once daily tenofovir/emtricitabine was initiated with documented malabsorption and delayed virologic suppression (VS). Dolutegravir dose titration with therapeutic drug monitoring (TDM) resulted in VS at month 12. ARV TDM with dose titration is an option for PLWH with malabsorptive states to maintain VS.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02017"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924000933/pdfft?md5=b70e807f77b2bc9af6b238b14be4df48&pid=1-s2.0-S2214250924000933-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141487725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical Imagery: Cytomegalovirus sialadenitis in a patient with B-cell acute lymphoblastic leukemia","authors":"Javier A. Baena-Del Valle ,&nbsp;Sergio D. Cruz-Romero ,&nbsp;Martha L. Romero-Prieto ,&nbsp;Adriana A. Flórez-Vargas ,&nbsp;Diana M. Palacios-Ortiz ,&nbsp;Guillermo E. Quintero-Vega ,&nbsp;Mauricio A. Palau-Lázaro","doi":"10.1016/j.idcr.2024.e02043","DOIUrl":"10.1016/j.idcr.2024.e02043","url":null,"abstract":"<div><p>Cytomegalovirus (CMV) can cause a broad range of diseases, with severity depending on immune status, comorbidities, and age. Initial CMV infection usually occurs in childhood and is typically asymptomatic, leading to lifelong latency. In immunocompromised patients, CMV can affect multiple organs, but salivary gland infections are rare. This study presents a case of a 66-year-old woman with B-cell acute lymphoblastic leukemia who developed swelling and pain in the right preauricular region during pre-transplant consolidation therapy. Despite a recent bone marrow biopsy indicating morphological remission and a flow cytometry analysis detecting only 0.04 % B lymphoblasts, she exhibited these symptoms. A CT scan revealed enlargement, hyperdensity, and enhancement of the right parotid glands, with accompanying subcutaneous edema. A biopsy of the right parotid gland showed a dense interstitial lymphoplasmacytic infiltrate with numerous Cowdry bodies and smaller granular cytoplasmic inclusions, all testing positive for CMV immunohistochemistry. The findings confirm the diagnosis of CMV sialadenitis in an immunocompromised patient. This case underscores the importance of considering CMV infections in similar clinical scenarios, particularly in patients with compromised immune systems.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02043"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001197/pdfft?md5=e9a7c6dad47f33eba12e39c79101f6a2&pid=1-s2.0-S2214250924001197-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mycobacterium cosmeticum catheter-related bloodstream infection in an immunocompetent patient: A case report and review of the literature","authors":"Julia S. Turock ,&nbsp;Colette J. Matysiak Match ,&nbsp;Kristina Adachi ,&nbsp;Karin Nielsen-Saines ,&nbsp;Shangxin Yang ,&nbsp;Sanchi Malhotra","doi":"10.1016/j.idcr.2024.e02051","DOIUrl":"10.1016/j.idcr.2024.e02051","url":null,"abstract":"<div><h3>Background</h3><p><em>Mycobacterium cosmeticum</em> is an emerging rapidly growing mycobacteria (RGM) species that has been rarely reported to cause human disease. RGM catheter-related bloodstream infections (CRBSI) are often challenging to treat given the need for line removal, variable species-dependent antimicrobial susceptibility, combination antimicrobial treatment, and historically longer courses of antibiotics.</p></div><div><h3>Case presentation</h3><p>We present a case of an immunocompetent pediatric patient with severe hemophilia B and <em>M. cosmeticum</em> CRBSI. While the patient’s hemophilia B precluded a standard line holiday, he successfully cleared his infection with two line exchanges followed by two weeks of antibiotics.</p></div><div><h3>Conclusions</h3><p>RGM, including emerging species <em>M. cosmeticum</em>, may be considered in patients with an indolent presentation of CRBSI. Our case suggests source control with shorter courses of antimicrobials can be successful.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02051"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001276/pdfft?md5=9b886bd4bcb567e6fbf91d8d92fd4bd7&pid=1-s2.0-S2214250924001276-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound findings of Fitz-Hugh-Curtis Syndrome (FHCS) associated with splenic tuberculosis in an HIV-positive male patient","authors":"Ibrahima Niang ,&nbsp;Daouda Thioub ,&nbsp;Mamadou Ly ,&nbsp;Abdourahmane Ndong ,&nbsp;Fallou Galass Niang ,&nbsp;Abdoulaye Dione Diop ,&nbsp;Sokhna Ba","doi":"10.1016/j.idcr.2024.e02036","DOIUrl":"10.1016/j.idcr.2024.e02036","url":null,"abstract":"<div><p>Fitz-Hugh-Curtis (FHCS) is characterized by an inflammation of the hepatic capsule concomitant or following pelvic infection due to <em>Chlamydia trachomatis</em> or <em>Neisseria gonorrhea</em>. It is a rare condition occurring most often in a woman of childbearing age and very rare in male patients. Splenic involvement is also a rare form of abdominal tuberculosis. The association of these two conditions is very uncommon. We report the exceptional case of a 58- year-old HIV-positive male patient, with whom abdominal ultrasound helped diagnose FHCS associated with abdominal tuberculosis invovlving the spleen.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02036"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001124/pdfft?md5=a4fb7863f78bfd6f08eb04bfa5b99aec&pid=1-s2.0-S2214250924001124-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141963007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cefazolin-induced hemolytic anemia in septic arthritis: A case report","authors":"S. Jawad Zafar ,&nbsp;Zachary Wynne ,&nbsp;Thomas John ,&nbsp;Lauren Groft Buzzalino ,&nbsp;Akira A. Shishido ,&nbsp;David J. Riedel","doi":"10.1016/j.idcr.2024.e02057","DOIUrl":"10.1016/j.idcr.2024.e02057","url":null,"abstract":"<div><p>A 50-year-old woman living with untreated HIV and injection drug use presented with right shoulder pain. The shoulder exam and computed tomography (CT) scan were concerning for septic arthritis. She was started on empiric vancomycin and cefepime and underwent right shoulder debridement and humeral head resection. Bone cultures grew methicillin sensitive <em>Staphylococcus aureus</em> (MSSA); empiric broad-spectrum antibiotics were changed to cefazolin. The patient subsequently developed severe anemia refractory to blood transfusions approximately 6 days later. Further evaluation disclosed hemolytic anemia attributable to cefazolin. Antibiotic therapy was switched from cefazolin to daptomycin, and the patient was started on prednisone. She had sustained improvement in hemoglobin values above 6 g/dL without requiring further transfusions prior to hospital discharge. Drug-induced immune hemolytic anemia from cefazolin is rare but has been reported primarily in the perioperative setting. Here, we present a case following initiation of treatment for septic arthritis.</p></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"37 ","pages":"Article e02057"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2214250924001331/pdfft?md5=fc10850bc36aaf21a9b683eaecf81019&pid=1-s2.0-S2214250924001331-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141985033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wound infection with multidrug-resistant Providencia rettgeri: About a case report and littérature review","authors":"S. Belmahi ,&nbsp;A. Saddari ,&nbsp;H. Zrouri ,&nbsp;Y. Sbibih ,&nbsp;C. Ben moussa ,&nbsp;O. Abdesselami ,&nbsp;K. Ghomari ,&nbsp;I. Alla ,&nbsp;S. Kaddouri ,&nbsp;A. Idrissi ,&nbsp;S. Ezrari ,&nbsp;E. Benaissa ,&nbsp;Y. Ben Lahlou ,&nbsp;M. Elouenass ,&nbsp;A. Maleb","doi":"10.1016/j.idcr.2024.e02115","DOIUrl":"10.1016/j.idcr.2024.e02115","url":null,"abstract":"<div><h3>Introduction and importance</h3><div><em>Providencia rettgeri</em>, a member of the <em>Morganellaceae</em> family within the <em>Enterobacterales</em> order, is predominantly associated with urinary tract infections in hospitalized individuals, particularly those with indwelling urinary catheters. However, wound infections caused by <em>P. rettgeri</em> are exceedingly rare, with an estimated incidence of around 0.1 %. Here, we present a case of wound infection in a healthy child caused by <em>P. rettgeri</em>, highlighting the rarity of the organism and emphasizing the importance of prompte identification and appropriate antibiotic therapy.</div></div><div><h3>Case report</h3><div>A 4-year-old child presented with a soft tissue abscess in the left calf, following an injury sustained from a tree trunk a few days prior. The patient underwent wound debridement and abscess drainage, followed by empirical antibiotic therapy with amoxicillin and clavulanic acid. Bacteriological samples collected intraoperatively revealed colonies of <em>P. rettgeri,</em> identified with high certainty using the BD Phoenix™ 100 automated system. Antimicrobial susceptibility testing showed resistance to several antibiotics but sensitivity to third-generation cephalosporins, amikacin, and aztreonam. Antibiotic therapy was adjusted accordingly, leading to clinical improvement and discharge after ten days of hospitalization</div></div><div><h3>Discussion</h3><div><em>P. rettgeri</em>, a Gram-negative bacillus, is a rare causative agent of wound infections. While predominantly associated with nosocomial urinary tract infections, it can rarely lead to various other infections, including wound infections, particularly in hospitalized or immunocompromised individuals. Resistance to multiple antibiotics, including carbapenems, poses challenges in treatment selection.</div></div><div><h3>Conclusion</h3><div>This case underscores the importance of considering <em>P. rettgeri</em> as a potential pathogen in wound infections, even in healthy individuals. Awareness of its presence and antibiotic susceptibility patterns is crucial for appropriate management and prevention of complications. Further studies are warranted to elucidate the epidemiology and clinical significance of <em>P. rettgeri</em> infections in different patient populations.</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"38 ","pages":"Article e02115"},"PeriodicalIF":1.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142700050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}